GUTR - BACSU - GREMLIN Contacts

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GUTR - Transcription activator GutR

UniProt:	P39143	Sequences: MAELENRKQFAQMLAPGVKTLKLHPDYKVRRKKNEKTGQSYIDKIALQLGVSPNTIKSWIGQMGANYIPGRIDDGKLFGMIWIILEKTDLDIEWLTDLLEATTIPVIKPALPVWAASCLKKAKILRKDGLFGAPSEGEIENVVKRLFHDRPGQETNALTEQPITHNLPSRWSGRFIGRSFDMEAIRQWMLSPSPVCLITGWAGMGKTTIALEAAYSCVDDTSVWPAFNSIIWVSADWKGLSFSDFLNTIAYQLGRKEQIDKSINVKRFVVRNALANYTREKPILLIVDSIDTAERDIHEFITSLPQGVKVLLTARENVKQTYRESFGEMTAIQLSGLDQTDAHEFFQQEVHHCLQTCNLPRKREKLEQLLHLSSDLKNEFISATAGNPKAMALSIAYMSDDDIPAQQLIHELGKAGYSLLELFEFLFGRTWDRCNEDTRKLWQTLCFFSKPPDEKSLAAAAGLDARRFHYAMEQMRSYALIQPERSQGRTQYLAHQTVVAYGEQHLSEQHEYEKEARNRWAHYYIDYAETHLKREQPNSIYWSYLLGRNLDQMKQEWPNILKVIQWASETEQKEILIELITRISHFLSRINLPLRIEYGRKAADAAHHLGQHTREAYFRIDTSGWALMEVNDLDGALQQIEAGLKILEQSDAHDAYDLKVWGHALKARLFLKDGQQEKAETILNEIENQPISPTIQHRVLLVRGDLSFARGYHVEAIQLYEAANEISSTYGGEKTIEAYFNLGVAYVKCDQFEKAEEAFEQMLYDKHNANQVELIYYHYGMAQLLYRKGEKTKAVESNQKAIRLIDSWEPAIGIRGEVERLARATKENE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	829 (652)
Sequences:	3896 (3443)
Seq/√Len:	134.8

BACSU - GUTR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
675_Q	678_K	5.841	1.00
632_D	635_G	5.744	1.00
751_Q	754_K	5.601	1.00
712_Y	715_E	5.240	1.00
790_E	793_K	4.582	1.00
198_I	334_L	3.788	1.00
128_D	134_P	3.480	1.00
667_A	683_L	3.401	1.00
435_N	474_Q	3.215	1.00
408_L	412_L	3.040	1.00
424_E	504_Q	2.927	1.00
624_G	640_I	2.850	1.00
182_M	213_A	2.817	1.00
592_L	595_R	2.797	1.00
619_R	639_Q	2.718	1.00
408_L	415_A	2.707	1.00
412_L	415_A	2.692	1.00
648_E	659_K	2.685	1.00
186_R	216_S	2.685	1.00
782_A	798_N	2.669	1.00
704_G	720_Y	2.654	1.00
743_G	759_F	2.596	1.00
727_S	732_G	2.584	1.00
295_R	298_H	2.540	1.00
408_L	411_E	2.532	1.00
380_F	409_I	2.511	1.00
338_D	341_D	2.447	1.00
228_N	232_W	2.417	1.00
441_L	461_A	2.411	1.00
759_F	780_G	2.388	1.00
647_L	658_L	2.378	1.00
150_R	153_Q	2.373	1.00
746_Y	758_A	2.355	1.00
230_I	235_A	2.332	1.00
556_E	559_N	2.309	1.00
607_H	642_A	2.297	1.00
767_H	774_L	2.286	1.00
607_H	615_E	2.263	1.00
379_E	413_G	2.231	1.00
739_Y	758_A	2.229	1.00
756_E	781_M	2.206	1.00
691_I	696_Q	2.199	1.00
778_H	797_S	2.153	1.00
656_Y	692_S	2.153	1.00
663_H	682_I	2.131	1.00
229_S	232_W	2.110	1.00
728_S	732_G	2.084	1.00
717_I	742_L	2.083	1.00
717_I	745_A	2.059	1.00
438_T	474_Q	2.048	1.00
278_T	283_I	2.028	1.00
405_A	412_L	1.998	1.00
518_N	522_H	1.984	1.00
232_W	235_A	1.973	1.00
795_V	799_Q	1.931	1.00
186_R	213_A	1.931	1.00
228_N	245_F	1.926	1.00
756_E	788_K	1.905	1.00
124_I	127_K	1.899	1.00
210_A	313_T	1.881	1.00
198_I	210_A	1.852	1.00
573_K	608_H	1.849	1.00
229_S	235_A	1.847	1.00
656_Y	659_K	1.833	1.00
290_I	312_L	1.827	1.00
274_L	278_T	1.802	1.00
411_E	415_A	1.796	1.00
563_V	579_L	1.793	1.00
240_L	245_F	1.780	1.00
342_A	391_M	1.753	1.00
612_H	649_Q	1.750	1.00
513_E	517_R	1.735	1.00
128_D	131_F	1.734	1.00
129_G	134_P	1.728	1.00
228_N	235_A	1.724	1.00
126_R	130_L	1.715	1.00
690_P	695_I	1.703	1.00
611_Q	614_R	1.703	1.00
171_W	212_E	1.694	1.00
228_N	231_I	1.692	1.00
185_I	213_A	1.688	1.00
648_E	685_E	1.680	1.00
745_A	749_C	1.679	1.00
431_W	443_Q	1.677	1.00
596_I	600_R	1.673	1.00
554_K	590_I	1.670	1.00
464_D	467_R	1.660	1.00
680_E	710_R	1.660	1.00
368_Q	373_S	1.659	1.00
212_E	216_S	1.659	1.00
405_A	408_L	1.657	1.00
346_F	377_K	1.649	1.00
724_N	727_S	1.640	1.00
530_T	534_R	1.639	1.00
724_N	728_S	1.628	1.00
127_K	132_G	1.626	1.00
775_I	805_I	1.620	1.00
410_H	415_A	1.606	1.00
142_V	146_L	1.604	1.00
637_L	673_D	1.604	1.00
410_H	414_K	1.593	1.00
245_F	249_I	1.589	1.00
739_Y	761_Q	1.587	1.00
144_K	148_H	1.574	1.00
583_I	587_L	1.572	1.00
129_G	132_G	1.568	1.00
802_I	818_V	1.563	1.00
207_T	289_S	1.550	1.00
723_A	727_S	1.550	1.00
728_S	735_T	1.550	1.00
406_Q	410_H	1.543	1.00
728_S	731_G	1.543	1.00
442_W	498_V	1.540	1.00
680_E	684_N	1.540	1.00
141_N	144_K	1.538	1.00
746_Y	754_K	1.535	1.00
228_N	249_I	1.535	1.00
717_I	749_C	1.535	1.00
721_E	742_L	1.532	1.00
616_A	647_L	1.527	1.00
728_S	761_Q	1.521	1.00
127_K	131_F	1.514	1.00
602_A	618_F	1.513	1.00
533_K	536_Q	1.506	1.00
437_D	467_R	1.500	1.00
480_L	498_V	1.489	1.00
660_V	690_P	1.483	1.00
126_R	129_G	1.475	1.00
680_E	703_R	1.475	1.00
664_A	702_V	1.468	1.00
691_I	722_A	1.467	1.00
765_D	768_N	1.463	1.00
183_E	187_Q	1.460	1.00
370_L	377_K	1.458	1.00
785_L	797_S	1.458	1.00
296_D	302_T	1.455	1.00
175_F	212_E	1.454	1.00
670_F	678_K	1.454	1.00
707_S	715_E	1.453	1.00
707_S	712_Y	1.452	1.00
296_D	300_F	1.448	1.00
700_L	719_L	1.446	1.00
767_H	800_K	1.442	1.00
623_S	627_L	1.439	1.00
369_L	373_S	1.436	1.00
644_L	659_K	1.424	1.00
627_L	635_G	1.423	1.00
379_E	383_A	1.413	1.00
717_I	721_E	1.412	1.00
727_S	731_G	1.407	1.00
339_Q	378_N	1.404	1.00
463_L	468_F	1.400	1.00
179_S	341_D	1.400	1.00
127_K	130_L	1.396	1.00
746_Y	751_Q	1.390	1.00
136_E	140_E	1.386	1.00
691_I	700_L	1.386	1.00
778_H	800_K	1.386	1.00
230_I	233_V	1.384	1.00
229_S	234_S	1.381	1.00
612_H	615_E	1.380	1.00
792_T	800_K	1.379	1.00
682_I	685_E	1.376	1.00
181_D	209_I	1.372	1.00
697_H	727_S	1.372	1.00
722_A	725_E	1.362	1.00
707_S	719_L	1.359	1.00
441_L	471_A	1.356	1.00
724_N	738_A	1.355	1.00
446_C	503_E	1.354	1.00
141_N	145_R	1.353	1.00
753_E	788_K	1.349	1.00
408_L	414_K	1.349	1.00
344_E	348_Q	1.346	1.00
596_I	623_S	1.342	1.00
619_R	642_A	1.341	1.00
623_S	639_Q	1.340	1.00
744_V	747_V	1.332	1.00
231_I	235_A	1.324	1.00
756_E	784_L	1.322	1.00
531_H	534_R	1.318	1.00
199_T	333_Q	1.317	1.00
703_R	708_F	1.314	1.00
627_L	632_D	1.312	1.00
663_H	685_E	1.306	1.00
670_F	682_I	1.304	1.00
342_A	386_G	1.302	1.00
143_V	147_F	1.297	1.00
406_Q	412_L	1.291	1.00
760_E	781_M	1.288	1.00
681_T	685_E	1.285	1.00
132_G	135_S	1.284	1.00
793_K	796_E	1.283	1.00
481_I	494_A	1.279	1.00
708_F	720_Y	1.278	1.00
733_E	768_N	1.276	1.00
522_H	575_I	1.275	1.00
756_E	785_L	1.271	1.00
654_D	659_K	1.262	1.00
806_D	818_V	1.261	1.00
446_C	502_G	1.258	1.00
274_L	285_L	1.255	1.00
427_F	498_V	1.255	1.00
448_F	520_W	1.255	1.00
131_F	134_P	1.253	1.00
685_E	688_N	1.252	1.00
705_D	708_F	1.246	1.00
724_N	732_G	1.246	1.00
172_S	211_L	1.245	1.00
693_P	729_T	1.242	1.00
127_K	135_S	1.242	1.00
249_I	252_Q	1.240	1.00
706_L	710_R	1.239	1.00
213_A	217_C	1.239	1.00
124_I	128_D	1.237	1.00
572_Q	575_I	1.236	1.00
621_D	665_L	1.235	1.00
720_Y	741_N	1.235	1.00
405_A	415_A	1.234	1.00
343_H	381_I	1.230	1.00
228_N	233_V	1.223	1.00
411_E	414_K	1.222	1.00
723_A	728_S	1.221	1.00
128_D	132_G	1.217	1.00
644_L	663_H	1.215	1.00
701_L	741_N	1.215	1.00
717_I	746_Y	1.212	1.00
412_L	416_G	1.212	1.00
660_V	689_Q	1.204	1.00
408_L	416_G	1.203	1.00
814_I	818_V	1.199	1.00
202_A	426_L	1.195	1.00
600_R	623_S	1.192	1.00
703_R	707_S	1.192	1.00
635_G	638_Q	1.191	0.99
410_H	413_G	1.190	0.99
135_S	147_F	1.189	0.99
815_R	818_V	1.189	0.99
785_L	793_K	1.188	0.99
642_A	645_K	1.188	0.99
343_H	377_K	1.186	0.99
577_I	614_R	1.186	0.99
438_T	475_M	1.185	0.99
771_Q	774_L	1.185	0.99
405_A	410_H	1.184	0.99
339_Q	382_S	1.180	0.99
186_R	217_C	1.180	0.99
724_N	731_G	1.180	0.99
619_R	646_I	1.174	0.99
406_Q	415_A	1.171	0.99
684_N	703_R	1.168	0.99
295_R	302_T	1.164	0.99
445_L	452_P	1.164	0.99
142_V	153_Q	1.163	0.99
440_K	444_T	1.156	0.99
532_L	536_Q	1.156	0.99
520_W	524_Y	1.155	0.99
780_G	783_Q	1.154	0.99
743_G	758_A	1.153	0.99
532_L	535_E	1.152	0.99
603_A	615_E	1.146	0.99
414_K	417_Y	1.142	0.99
708_F	713_H	1.142	0.99
727_S	730_Y	1.140	0.99
723_A	731_G	1.140	0.99
260_D	264_N	1.138	0.99
431_W	439_R	1.135	0.99
212_E	215_Y	1.132	0.99
267_R	270_V	1.132	0.99
554_K	586_F	1.127	0.99
584_S	599_G	1.126	0.99
736_I	739_Y	1.125	0.99
519_R	522_H	1.123	0.99
680_E	706_L	1.123	0.99
377_K	405_A	1.123	0.99
747_V	784_L	1.119	0.99
531_H	535_E	1.117	0.99
124_I	130_L	1.117	0.99
671_L	679_A	1.116	0.99
530_T	535_E	1.114	0.99
458_A	468_F	1.114	0.99
637_L	669_L	1.112	0.99
786_Y	798_N	1.106	0.99
775_I	801_A	1.106	0.99
341_D	344_E	1.104	0.99
229_S	289_S	1.101	0.99
295_R	300_F	1.094	0.99
142_V	150_R	1.091	0.99
137_G	141_N	1.090	0.99
189_M	217_C	1.090	0.99
717_I	720_Y	1.089	0.99
756_E	760_E	1.088	0.99
696_Q	700_L	1.086	0.99
779_Y	805_I	1.083	0.99
700_L	722_A	1.082	0.99
641_E	666_K	1.079	0.99
670_F	675_Q	1.079	0.99
640_I	665_L	1.078	0.99
763_L	777_Y	1.072	0.99
648_E	663_H	1.072	0.99
627_L	639_Q	1.071	0.99
637_L	641_E	1.069	0.99
405_A	414_K	1.068	0.99
428_G	501_Y	1.065	0.99
528_A	533_K	1.061	0.99
696_Q	703_R	1.060	0.99
703_R	719_L	1.060	0.99
693_P	696_Q	1.059	0.99
534_R	537_P	1.059	0.99
655_A	658_L	1.057	0.99
125_L	128_D	1.056	0.99
181_D	335_S	1.056	0.99
441_L	468_F	1.055	0.99
602_A	605_A	1.055	0.99
740_F	744_V	1.054	0.99
700_L	707_S	1.054	0.99
757_E	761_Q	1.052	0.99
435_N	438_T	1.046	0.99
342_A	381_I	1.045	0.99
346_F	395_I	1.044	0.99
813_G	816_G	1.040	0.99
436_E	439_R	1.039	0.99
370_L	373_S	1.039	0.99
659_K	663_H	1.037	0.99
369_L	374_S	1.033	0.99
527_Y	533_K	1.033	0.99
124_I	129_G	1.031	0.99
407_Q	410_H	1.031	0.99
680_E	683_L	1.031	0.99
680_E	707_S	1.030	0.99
615_E	619_R	1.028	0.99
669_L	673_D	1.027	0.98
442_W	501_Y	1.026	0.98
725_E	729_T	1.024	0.98
125_L	129_G	1.018	0.98
463_L	471_A	1.017	0.98
683_L	702_V	1.015	0.98
130_L	135_S	1.013	0.98
529_E	533_K	1.012	0.98
557_W	592_L	1.011	0.98
616_A	658_L	1.010	0.98
190_L	220_D	1.009	0.98
406_Q	414_K	1.008	0.98
766_K	777_Y	1.007	0.98
343_H	378_N	1.006	0.98
607_H	619_R	1.005	0.98
793_K	797_S	1.004	0.98
759_F	777_Y	1.002	0.98
713_H	745_A	1.001	0.98
229_S	233_V	1.001	0.98
231_I	234_S	0.998	0.98
230_I	234_S	0.997	0.98
519_R	524_Y	0.993	0.98
574_E	578_E	0.990	0.98
233_V	236_D	0.988	0.98
189_M	309_K	0.984	0.98
458_A	465_A	0.984	0.98
232_W	236_D	0.982	0.98
295_R	299_E	0.981	0.98
247_N	270_V	0.981	0.98
702_V	706_L	0.981	0.98
230_I	236_D	0.979	0.98
684_N	688_N	0.978	0.98
742_L	746_Y	0.977	0.98
728_S	739_Y	0.971	0.98
406_Q	411_E	0.971	0.98
131_F	135_S	0.970	0.98
802_I	806_D	0.968	0.98
271_R	274_L	0.967	0.98
549_N	552_Q	0.967	0.98
698_R	701_L	0.966	0.98
792_T	796_E	0.965	0.98
654_D	662_G	0.962	0.98
146_L	149_D	0.961	0.98
576_L	580_I	0.961	0.98
687_E	696_Q	0.960	0.98
637_L	670_F	0.959	0.98
701_L	705_D	0.959	0.98
527_Y	530_T	0.957	0.98
742_L	758_A	0.957	0.98
296_D	299_E	0.956	0.98
126_R	131_F	0.956	0.98
214_A	286_I	0.953	0.98
381_I	391_M	0.952	0.98
270_V	277_Y	0.952	0.98
136_E	143_V	0.951	0.98
743_G	780_G	0.951	0.98
666_K	682_I	0.949	0.97
615_E	646_I	0.947	0.97
452_P	457_L	0.943	0.97
135_S	143_V	0.942	0.97
654_D	666_K	0.940	0.97
413_G	416_G	0.935	0.97
785_L	790_E	0.935	0.97
600_R	604_D	0.933	0.97
738_A	742_L	0.932	0.97
697_H	700_L	0.932	0.97
702_V	705_D	0.930	0.97
176_I	348_Q	0.930	0.97
349_E	392_A	0.927	0.97
640_I	666_K	0.926	0.97
181_D	184_A	0.924	0.97
185_I	196_C	0.923	0.97
273_A	277_Y	0.922	0.97
552_Q	556_E	0.921	0.97
724_N	742_L	0.921	0.97
777_Y	780_G	0.920	0.97
426_L	429_R	0.919	0.97
577_I	602_A	0.915	0.97
814_I	817_E	0.911	0.97
404_P	408_L	0.911	0.97
637_L	666_K	0.910	0.97
671_L	709_A	0.909	0.97
763_L	767_H	0.906	0.97
666_K	671_L	0.906	0.97
298_H	327_G	0.906	0.97
759_F	784_L	0.904	0.97
698_R	702_V	0.904	0.97
130_L	134_P	0.902	0.97
650_S	654_D	0.901	0.97
687_E	691_I	0.901	0.97
380_F	405_A	0.900	0.97
740_F	777_Y	0.900	0.97
587_L	592_L	0.898	0.96
596_I	627_L	0.897	0.96
453_D	456_S	0.895	0.96
811_A	815_R	0.891	0.96
195_V	301_I	0.889	0.96
697_H	703_R	0.888	0.96
146_L	153_Q	0.888	0.96
577_I	618_F	0.887	0.96
704_G	742_L	0.887	0.96
339_Q	343_H	0.885	0.96
247_N	251_Y	0.884	0.96
339_Q	386_G	0.881	0.96
557_W	595_R	0.879	0.96
802_I	814_I	0.879	0.96
139_I	143_V	0.877	0.96
270_V	273_A	0.876	0.96
535_E	538_N	0.874	0.96
723_A	730_Y	0.870	0.96
700_L	706_L	0.869	0.96
124_I	132_G	0.865	0.96
293_A	320_Q	0.864	0.96
460_A	516_A	0.864	0.96
490_T	493_L	0.864	0.96
719_L	722_A	0.863	0.96
667_A	682_I	0.860	0.96
456_S	523_Y	0.857	0.95
760_E	785_L	0.854	0.95
766_K	773_E	0.854	0.95
770_N	773_E	0.854	0.95
688_N	692_S	0.853	0.95
580_I	598_Y	0.853	0.95
145_R	150_R	0.852	0.95
760_E	793_K	0.851	0.95
660_V	686_I	0.849	0.95
704_G	723_A	0.847	0.95
199_T	331_A	0.847	0.95
561_L	595_R	0.846	0.95
374_S	378_N	0.846	0.95
404_P	407_Q	0.844	0.95
637_L	675_Q	0.844	0.95
659_K	666_K	0.844	0.95
444_T	516_A	0.843	0.95
544_Y	560_I	0.842	0.95
440_K	512_Y	0.841	0.95
670_F	673_D	0.841	0.95
666_K	670_F	0.839	0.95
398_M	405_A	0.839	0.95
763_L	774_L	0.838	0.95
762_M	777_Y	0.837	0.95
457_L	460_A	0.836	0.95
531_H	536_Q	0.834	0.95
270_V	274_L	0.830	0.95
650_S	655_A	0.830	0.95
446_C	506_L	0.829	0.95
442_W	502_G	0.829	0.95
268_F	271_R	0.829	0.95
727_S	734_K	0.829	0.95
126_R	132_G	0.829	0.95
210_A	286_I	0.829	0.95
518_N	572_Q	0.828	0.94
380_F	391_M	0.828	0.94
131_F	147_F	0.827	0.94
599_G	622_T	0.826	0.94
747_V	787_R	0.825	0.94
663_H	689_Q	0.824	0.94
771_Q	807_S	0.824	0.94
174_R	348_Q	0.823	0.94
752_F	784_L	0.823	0.94
548_R	582_R	0.823	0.94
704_G	708_F	0.822	0.94
743_G	762_M	0.819	0.94
586_F	590_I	0.819	0.94
531_H	549_N	0.819	0.94
739_Y	765_D	0.817	0.94
516_A	519_R	0.817	0.94
740_F	780_G	0.815	0.94
718_Q	722_A	0.814	0.94
596_I	626_A	0.812	0.94
231_I	236_D	0.811	0.94
667_A	686_I	0.811	0.94
437_D	471_A	0.811	0.94
314_A	318_V	0.810	0.94
132_G	136_E	0.810	0.94
805_I	813_G	0.807	0.94
149_D	153_Q	0.807	0.94
683_L	699_V	0.806	0.94
659_K	685_E	0.804	0.94
426_L	431_W	0.803	0.94
723_A	726_I	0.803	0.94
704_G	741_N	0.803	0.94
667_A	679_A	0.802	0.94
136_E	147_F	0.801	0.93
697_H	701_L	0.800	0.93
140_E	144_K	0.800	0.93
447_F	520_W	0.800	0.93
208_T	212_E	0.799	0.93
778_H	792_T	0.798	0.93
641_E	678_K	0.798	0.93
267_R	271_R	0.797	0.93
251_Y	269_V	0.797	0.93
538_N	544_Y	0.796	0.93
676_Q	706_L	0.795	0.93
744_V	780_G	0.794	0.93
350_V	395_I	0.791	0.93
445_L	457_L	0.790	0.93
373_S	376_L	0.790	0.93
774_L	804_L	0.790	0.93
724_N	730_Y	0.789	0.93
411_E	416_G	0.789	0.93
214_A	284_L	0.789	0.93
752_F	756_E	0.789	0.93
405_A	416_G	0.788	0.93
367_E	373_S	0.787	0.93
438_T	471_A	0.785	0.93
743_G	781_M	0.785	0.93
662_G	666_K	0.784	0.93
677_E	681_T	0.784	0.93
129_G	135_S	0.784	0.93
615_E	642_A	0.784	0.93
601_K	604_D	0.783	0.93
208_T	392_A	0.782	0.93
140_E	143_V	0.781	0.93
699_V	702_V	0.780	0.93
404_P	412_L	0.780	0.93
713_H	717_I	0.780	0.93
744_V	759_F	0.778	0.92
714_V	749_C	0.777	0.92
143_V	146_L	0.777	0.92
197_L	312_L	0.777	0.92
703_R	710_R	0.776	0.92
298_H	302_T	0.776	0.92
210_A	311_L	0.775	0.92
292_T	295_R	0.774	0.92
245_F	252_Q	0.772	0.92
695_I	699_V	0.772	0.92
568_S	571_E	0.772	0.92
337_L	345_F	0.771	0.92
644_L	648_E	0.769	0.92
204_M	336_G	0.765	0.92
557_W	587_L	0.764	0.92
720_Y	724_N	0.764	0.92
718_Q	721_E	0.764	0.92
563_V	567_A	0.764	0.92
756_E	790_E	0.764	0.92
183_E	186_R	0.764	0.92
127_K	134_P	0.764	0.92
813_G	817_E	0.763	0.92
295_R	303_S	0.763	0.92
752_F	788_K	0.762	0.92
296_D	301_I	0.762	0.92
565_Q	597_E	0.761	0.92
561_L	565_Q	0.761	0.92
147_F	150_R	0.759	0.92
211_L	215_Y	0.759	0.92
296_D	304_L	0.759	0.92
384_T	394_S	0.754	0.91
132_G	147_F	0.754	0.91
146_L	150_R	0.752	0.91
144_K	147_F	0.751	0.91
774_L	800_K	0.750	0.91
521_A	575_I	0.750	0.91
528_A	534_R	0.747	0.91
721_E	754_K	0.747	0.91
644_L	666_K	0.746	0.91
796_E	800_K	0.746	0.91
246_L	254_G	0.746	0.91
596_I	630_V	0.745	0.91
204_M	335_S	0.743	0.91
696_Q	708_F	0.742	0.91
645_K	648_E	0.742	0.91
346_F	380_F	0.740	0.90
761_Q	764_Y	0.740	0.90
700_L	703_R	0.737	0.90
202_A	291_D	0.737	0.90
782_A	801_A	0.736	0.90
641_E	645_K	0.734	0.90
533_K	537_P	0.734	0.90
524_Y	559_N	0.732	0.90
233_V	289_S	0.732	0.90
346_F	381_I	0.731	0.90
760_E	764_Y	0.730	0.90
181_D	334_L	0.729	0.90
521_A	567_A	0.729	0.90
731_G	734_K	0.725	0.90
242_F	249_I	0.723	0.89
410_H	416_G	0.723	0.89
667_A	701_L	0.720	0.89
394_S	420_L	0.720	0.89
145_R	149_D	0.718	0.89
714_V	717_I	0.718	0.89
147_F	151_P	0.718	0.89
521_A	524_Y	0.718	0.89
527_Y	531_H	0.716	0.89
667_A	671_L	0.716	0.89
124_I	147_F	0.715	0.89
811_A	814_I	0.715	0.89
556_E	560_I	0.715	0.89
476_R	481_I	0.715	0.89
125_L	130_L	0.714	0.89
709_A	720_Y	0.714	0.89
778_H	804_L	0.713	0.89
530_T	533_K	0.713	0.89
521_A	563_V	0.712	0.89
211_L	214_A	0.712	0.89
740_F	743_G	0.711	0.89
711_G	720_Y	0.711	0.89
746_Y	749_C	0.710	0.89
785_L	788_K	0.710	0.89
512_Y	515_E	0.710	0.89
784_L	788_K	0.709	0.89
428_G	505_H	0.709	0.89
124_I	131_F	0.708	0.88
406_Q	416_G	0.707	0.88
207_T	211_L	0.707	0.88
664_A	683_L	0.706	0.88
678_K	682_I	0.704	0.88
603_A	619_R	0.704	0.88
124_I	134_P	0.703	0.88
704_G	716_A	0.703	0.88
269_V	273_A	0.702	0.88
806_D	814_I	0.700	0.88
720_Y	723_A	0.700	0.88
576_L	579_L	0.699	0.88
138_E	142_V	0.698	0.88
671_L	706_L	0.697	0.88
747_V	780_G	0.697	0.88
228_N	282_P	0.694	0.87
609_L	614_R	0.694	0.87
463_L	467_R	0.693	0.87
402_D	412_L	0.692	0.87
678_K	681_T	0.692	0.87
638_Q	642_A	0.691	0.87
298_H	304_L	0.690	0.87
407_Q	411_E	0.689	0.87
643_G	662_G	0.689	0.87
697_H	702_V	0.689	0.87
550_L	554_K	0.686	0.87
184_A	187_Q	0.686	0.87
301_I	308_V	0.685	0.87
527_Y	535_E	0.685	0.87
337_L	386_G	0.683	0.87
676_Q	680_E	0.683	0.87
641_E	648_E	0.683	0.87
795_V	800_K	0.682	0.87
572_Q	576_L	0.681	0.86
810_P	813_G	0.680	0.86
754_K	757_E	0.680	0.86
527_Y	537_P	0.680	0.86
295_R	304_L	0.680	0.86
241_S	245_F	0.680	0.86
671_L	676_Q	0.679	0.86
438_T	441_L	0.677	0.86
779_Y	817_E	0.677	0.86
181_D	332_I	0.677	0.86
460_A	520_W	0.676	0.86
636_A	669_L	0.674	0.86
249_I	274_L	0.674	0.86
779_Y	813_G	0.673	0.86
202_A	289_S	0.672	0.86
505_H	508_E	0.672	0.86
256_K	260_D	0.669	0.85
783_Q	798_N	0.669	0.85
298_H	301_I	0.667	0.85
649_Q	654_D	0.666	0.85
699_V	705_D	0.664	0.85
784_L	787_R	0.663	0.85
124_I	135_S	0.663	0.85
264_N	273_A	0.662	0.85
532_L	538_N	0.660	0.85
739_Y	746_Y	0.660	0.85
181_D	198_I	0.660	0.85
227_F	231_I	0.659	0.85
204_M	388_P	0.657	0.84
529_E	532_L	0.656	0.84
368_Q	372_L	0.655	0.84
596_I	632_D	0.654	0.84
130_L	147_F	0.653	0.84
184_A	188_W	0.652	0.84
779_Y	798_N	0.652	0.84
741_N	744_V	0.652	0.84
781_M	797_S	0.651	0.84
254_G	260_D	0.650	0.84
448_F	452_P	0.649	0.84
702_V	710_R	0.648	0.84
299_E	303_S	0.648	0.84
242_F	245_F	0.648	0.84
171_W	215_Y	0.646	0.83
274_L	277_Y	0.646	0.83
444_T	461_A	0.646	0.83
660_V	666_K	0.646	0.83
767_H	778_H	0.646	0.83
227_F	230_I	0.646	0.83
142_V	149_D	0.644	0.83
796_E	799_Q	0.644	0.83
723_A	732_G	0.642	0.83
662_G	665_L	0.642	0.83
566_W	570_T	0.642	0.83
621_D	625_W	0.642	0.83
527_Y	534_R	0.641	0.83
454_E	458_A	0.640	0.83
720_Y	745_A	0.638	0.83
156_N	159_T	0.637	0.83
431_W	505_H	0.637	0.83
650_S	659_K	0.637	0.83
402_D	415_A	0.636	0.82
752_F	787_R	0.635	0.82
202_A	319_K	0.633	0.82
633_L	669_L	0.630	0.82
720_Y	738_A	0.630	0.82
677_E	710_R	0.630	0.82
686_I	689_Q	0.628	0.82
684_N	715_E	0.628	0.82
456_S	524_Y	0.628	0.82
393_L	396_A	0.627	0.82
195_V	312_L	0.625	0.81
379_E	382_S	0.624	0.81
564_I	580_I	0.623	0.81
701_L	720_Y	0.622	0.81
705_D	709_A	0.622	0.81
724_N	739_Y	0.622	0.81
747_V	752_F	0.620	0.81
139_I	147_F	0.620	0.81
643_G	646_I	0.620	0.81
742_L	745_A	0.619	0.81
701_L	708_F	0.618	0.81
202_A	315_R	0.618	0.81
800_K	804_L	0.617	0.81
783_Q	786_Y	0.617	0.81
404_P	415_A	0.615	0.80
188_W	196_C	0.613	0.80
744_V	748_K	0.613	0.80
577_I	606_A	0.613	0.80
776_Y	805_I	0.612	0.80
728_S	734_K	0.612	0.80
640_I	662_G	0.611	0.80
573_K	605_A	0.610	0.80
196_C	309_K	0.609	0.80
401_D	412_L	0.607	0.79
248_T	252_Q	0.607	0.79
411_E	469_H	0.606	0.79
402_D	406_Q	0.606	0.79
527_Y	532_L	0.606	0.79
295_R	301_I	0.606	0.79
381_I	386_G	0.605	0.79
168_P	211_L	0.605	0.79
408_L	413_G	0.605	0.79
564_I	598_Y	0.603	0.79
624_G	643_G	0.603	0.79
402_D	405_A	0.603	0.79
405_A	411_E	0.601	0.79
184_A	330_T	0.601	0.79
581_T	617_Y	0.601	0.79
151_P	154_E	0.600	0.79
560_I	582_R	0.599	0.79
712_Y	751_Q	0.597	0.78
175_F	341_D	0.596	0.78
346_F	391_M	0.595	0.78
124_I	133_A	0.595	0.78
346_F	350_V	0.595	0.78
270_V	279_R	0.594	0.78
805_I	810_P	0.594	0.78
143_V	149_D	0.593	0.78
530_T	536_Q	0.593	0.78
128_D	138_E	0.591	0.78
204_M	387_N	0.590	0.78
129_G	138_E	0.590	0.78
346_F	394_S	0.589	0.77
565_Q	569_E	0.589	0.77
373_S	377_K	0.588	0.77
135_S	140_E	0.586	0.77
428_G	432_D	0.586	0.77
505_H	509_Q	0.586	0.77
597_E	601_K	0.586	0.77
707_S	710_R	0.585	0.77
464_D	468_F	0.585	0.77
567_A	576_L	0.584	0.77
227_F	235_A	0.584	0.77
145_R	152_G	0.583	0.77
159_T	162_P	0.583	0.77
571_E	576_L	0.583	0.77
517_R	566_W	0.582	0.77
723_A	738_A	0.582	0.77
384_T	393_L	0.581	0.76
606_A	610_G	0.581	0.76
289_S	390_A	0.580	0.76
613_T	655_A	0.577	0.76
533_K	538_N	0.577	0.76
721_E	725_E	0.577	0.76
804_L	807_S	0.577	0.76
383_A	413_G	0.576	0.76
705_D	720_Y	0.575	0.76
689_Q	692_S	0.575	0.76
600_R	635_G	0.574	0.76
175_F	208_T	0.573	0.76
136_E	149_D	0.573	0.76
702_V	707_S	0.572	0.75
166_N	249_I	0.572	0.75
528_A	535_E	0.572	0.75
727_S	738_A	0.572	0.75
786_Y	791_K	0.571	0.75
171_W	211_L	0.570	0.75
369_L	372_L	0.570	0.75
708_F	748_K	0.570	0.75
595_R	598_Y	0.568	0.75
427_F	442_W	0.568	0.75
125_L	131_F	0.568	0.75
413_G	417_Y	0.568	0.75
347_Q	371_H	0.567	0.75
528_A	532_L	0.567	0.75
289_S	429_R	0.567	0.75
519_R	523_Y	0.567	0.75
130_L	133_A	0.567	0.75
213_A	311_L	0.566	0.75
577_I	584_S	0.565	0.74
805_I	808_W	0.564	0.74
646_I	649_Q	0.564	0.74
132_G	143_V	0.564	0.74
777_Y	781_M	0.563	0.74
271_R	275_A	0.562	0.74
659_K	689_Q	0.562	0.74
367_E	370_L	0.562	0.74
516_A	524_Y	0.561	0.74
758_A	761_Q	0.561	0.74
297_I	300_F	0.561	0.74
165_H	218_V	0.561	0.74
367_E	371_H	0.560	0.74
645_K	649_Q	0.560	0.74
606_A	615_E	0.560	0.74
681_T	684_N	0.560	0.74
634_D	673_D	0.559	0.74
494_A	498_V	0.558	0.74
764_Y	768_N	0.558	0.74
204_M	334_L	0.558	0.74
684_N	712_Y	0.557	0.73
624_G	639_Q	0.556	0.73
126_R	134_P	0.556	0.73
402_D	416_G	0.556	0.73
553_M	556_E	0.555	0.73
349_E	395_I	0.555	0.73
402_D	408_L	0.554	0.73
373_S	406_Q	0.554	0.73
716_A	723_A	0.553	0.73
466_R	512_Y	0.552	0.73
603_A	623_S	0.551	0.73
227_F	232_W	0.551	0.73
174_R	208_T	0.550	0.73
393_L	430_T	0.550	0.73
131_F	136_E	0.550	0.73
145_R	148_H	0.549	0.72
149_D	152_G	0.548	0.72
245_F	248_T	0.547	0.72
683_L	689_Q	0.547	0.72
201_W	385_A	0.546	0.72
544_Y	547_G	0.546	0.72
544_Y	548_R	0.545	0.72
440_K	443_Q	0.543	0.72
667_A	676_Q	0.543	0.72
680_E	712_Y	0.543	0.72
528_A	531_H	0.543	0.72
606_A	618_F	0.543	0.72
451_P	489_R	0.543	0.72
587_L	598_Y	0.542	0.71
142_V	152_G	0.542	0.71
423_F	497_T	0.542	0.71
666_K	672_K	0.541	0.71
781_M	785_L	0.541	0.71
443_Q	512_Y	0.538	0.71
444_T	460_A	0.538	0.71
455_K	465_A	0.538	0.71
613_T	616_A	0.538	0.71
699_V	703_R	0.538	0.71
588_S	593_P	0.537	0.71
345_F	391_M	0.537	0.71
655_A	660_V	0.536	0.71
747_V	759_F	0.536	0.71
398_M	403_I	0.536	0.71
135_S	146_L	0.535	0.70
137_G	147_F	0.533	0.70
576_L	586_F	0.533	0.70
624_G	666_K	0.532	0.70
280_E	307_G	0.532	0.70
520_W	523_Y	0.532	0.70
228_N	236_D	0.532	0.70
230_I	290_I	0.532	0.70
771_Q	804_L	0.532	0.70
676_Q	709_A	0.532	0.70
529_E	536_Q	0.531	0.70
719_L	723_A	0.531	0.70
298_H	303_S	0.531	0.70
267_R	277_Y	0.530	0.70
553_M	557_W	0.529	0.70
661_W	665_L	0.529	0.70
667_A	702_V	0.529	0.70
656_Y	689_Q	0.529	0.70
551_D	555_Q	0.527	0.69
704_G	710_R	0.527	0.69
667_A	703_R	0.526	0.69
724_N	733_E	0.526	0.69
407_Q	414_K	0.525	0.69
407_Q	416_G	0.525	0.69
772_V	805_I	0.525	0.69
666_K	687_E	0.524	0.69
296_D	303_S	0.523	0.69
736_I	743_G	0.523	0.69
288_D	496_Q	0.523	0.69
685_E	692_S	0.522	0.69
381_I	394_S	0.521	0.68
517_R	524_Y	0.521	0.68
245_F	254_G	0.520	0.68
654_D	660_V	0.520	0.68
339_Q	381_I	0.519	0.68
616_A	643_G	0.518	0.68
407_Q	412_L	0.518	0.68
459_A	526_D	0.517	0.68
469_H	473_E	0.517	0.68
461_A	471_A	0.516	0.68
744_V	783_Q	0.516	0.68
401_D	416_G	0.515	0.68
662_G	667_A	0.515	0.68
202_A	288_D	0.515	0.68
687_E	700_L	0.514	0.67
269_V	272_N	0.514	0.67
741_N	780_G	0.513	0.67
700_L	726_I	0.513	0.67
446_C	524_Y	0.512	0.67
442_W	446_C	0.511	0.67
684_N	707_S	0.511	0.67
550_L	590_I	0.511	0.67
662_G	668_R	0.511	0.67
174_R	392_A	0.511	0.67
662_G	683_L	0.510	0.67
555_Q	558_P	0.509	0.67
612_H	646_I	0.508	0.67
559_N	563_V	0.508	0.67
650_S	658_L	0.507	0.66
518_N	575_I	0.507	0.66
404_P	413_G	0.507	0.66
708_F	744_V	0.507	0.66
135_S	139_I	0.506	0.66
609_L	612_H	0.506	0.66
202_A	317_N	0.506	0.66
179_S	183_E	0.506	0.66
207_T	288_D	0.506	0.66
454_E	468_F	0.506	0.66
482_Q	493_L	0.505	0.66
647_L	662_G	0.505	0.66
124_I	137_G	0.505	0.66
302_T	310_V	0.504	0.66
378_N	382_S	0.504	0.66
401_D	405_A	0.503	0.66
639_Q	642_A	0.503	0.66
633_L	673_D	0.502	0.66
813_G	818_V	0.502	0.66
606_A	614_R	0.500	0.65
404_P	411_E	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1z6tA	1	0.6828	100	0.698	Contact Map
2a5yB	2	0.5609	100	0.72	Contact Map
3sfzA	1	0.6864	100	0.72	Contact Map
1vt4I	4	0.6526	100	0.748	Contact Map
2qenA	1	0.3691	100	0.807	Contact Map
4jhrA	2	0.2799	99.9	0.815	Contact Map
2fnaA	1	0.3643	99.9	0.817	Contact Map
3sf4A	1	0.3993	99.9	0.822	Contact Map
4a1sA	1	0.3703	99.9	0.824	Contact Map
3ulqA	1	0.3534	99.9	0.833	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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