PDP - BACSU - GREMLIN Contacts

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PDP - Pyrimidine-nucleoside phosphorylase

UniProt:	P39142	Sequences: MRMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAIFFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALDVPVAKMSGRGLGHTGGTIDKLEAIMGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMVRIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVVLAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAYQIDVPAKEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYANRENVDEVIAKVYDNIRIAAEAKAPKLIHTLITE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	433 (421)
Sequences:	2202 (1404)
Seq/√Len:	68.4

ECOLI - TYPH
BACSU - PDP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
41_L	45_I	4.776	1.00
15_E	51_S	4.219	1.00
215_A	429_T	3.831	1.00
13_G	48_Q	3.606	1.00
381_R	396_T	3.501	1.00
9_K	20_E	3.332	1.00
24_F	38_A	3.313	1.00
18_T	57_D	3.298	1.00
308_K	311_D	3.246	1.00
131_H	138_E	3.199	1.00
141_K	145_R	3.085	1.00
343_A	389_E	2.859	1.00
101_A	299_V	2.839	1.00
53_R	57_D	2.816	1.00
210_T	213_D	2.772	1.00
347_S	418_A	2.759	1.00
15_E	53_R	2.675	1.00
202_T	236_I	2.586	1.00
382_K	392_E	2.563	1.00
102_L	299_V	2.560	1.00
341_K	412_Y	2.530	1.00
247_I	354_I	2.420	1.00
298_E	302_N	2.415	1.00
299_V	302_N	2.375	1.00
246_A	379_M	2.361	1.00
92_T	150_V	2.283	1.00
343_A	390_K	2.270	1.00
67_E	156_N	2.260	1.00
135_T	138_E	2.234	1.00
342_E	419_A	2.219	1.00
98_L	296_L	2.194	1.00
6_I	24_F	2.133	1.00
121_I	132_V	2.128	1.00
354_I	411_V	2.110	1.00
52_D	223_R	2.110	1.00
209_K	352_D	2.110	1.00
286_A	292_A	2.106	1.00
276_G	296_L	2.099	1.00
219_K	223_R	2.096	1.00
24_F	41_L	2.085	1.00
258_D	263_E	2.066	1.00
142_L	146_D	2.052	1.00
339_P	393_P	2.032	1.00
56_A	227_N	2.016	1.00
277_S	292_A	2.015	1.00
213_D	216_E	1.989	1.00
337_D	396_T	1.979	1.00
273_L	296_L	1.967	1.00
350_V	353_E	1.956	1.00
367_T	370_D	1.949	1.00
18_T	53_R	1.948	1.00
99_V	279_M	1.938	1.00
63_V	189_I	1.920	1.00
146_D	315_N	1.888	1.00
26_N	30_D	1.882	1.00
18_T	22_Q	1.875	1.00
104_V	285_K	1.870	1.00
358_A	363_A	1.869	1.00
338_V	411_V	1.867	1.00
259_T	269_H	1.864	1.00
75_E	144_N	1.847	1.00
9_K	14_K	1.837	1.00
297_E	301_K	1.827	1.00
138_E	141_K	1.823	1.00
6_I	41_L	1.813	1.00
93_L	253_V	1.788	1.00
321_S	328_K	1.788	1.00
278_Q	430_L	1.763	1.00
346_V	349_I	1.745	1.00
366_A	370_D	1.736	1.00
373_D	400_N	1.735	1.00
28_Y	38_A	1.725	1.00
202_T	214_A	1.676	0.99
64_N	68_T	1.671	0.99
27_G	32_S	1.665	0.99
251_L	379_M	1.658	0.99
335_Q	396_T	1.648	0.99
345_V	421_A	1.642	0.99
94_V	268_L	1.628	0.99
299_V	304_K	1.613	0.99
225_G	232_T	1.612	0.99
12_N	46_F	1.601	0.99
349_I	415_I	1.596	0.99
298_E	304_K	1.590	0.99
63_V	68_T	1.590	0.99
293_R	297_E	1.582	0.99
56_A	228_V	1.570	0.99
127_I	313_L	1.555	0.99
79_V	195_A	1.506	0.99
98_L	276_G	1.498	0.99
91_T	268_L	1.480	0.99
8_I	12_N	1.469	0.99
307_E	311_D	1.457	0.99
181_A	220_A	1.456	0.99
376_V	399_A	1.451	0.98
102_L	280_V	1.449	0.98
98_L	299_V	1.448	0.98
142_L	315_N	1.445	0.98
198_L	221_M	1.433	0.98
269_H	297_E	1.421	0.98
336_I	408_I	1.421	0.98
134_L	142_L	1.417	0.98
189_I	228_V	1.413	0.98
253_V	256_A	1.408	0.98
50_M	178_P	1.406	0.98
42_A	164_L	1.406	0.98
251_L	398_Y	1.405	0.98
269_H	301_K	1.400	0.98
408_I	412_Y	1.397	0.98
261_K	306_L	1.393	0.98
379_M	398_Y	1.390	0.98
389_E	392_E	1.390	0.98
90_T	244_G	1.379	0.98
333_A	400_N	1.366	0.98
338_V	395_V	1.359	0.98
337_D	393_P	1.355	0.98
378_I	395_V	1.351	0.98
95_L	276_G	1.349	0.98
285_K	295_K	1.341	0.97
55_R	220_A	1.337	0.97
210_T	214_A	1.332	0.97
8_I	172_G	1.320	0.97
226_N	232_T	1.320	0.97
245_F	386_D	1.310	0.97
267_D	383_K	1.305	0.97
211_E	215_A	1.305	0.97
353_E	410_K	1.297	0.97
139_F	149_A	1.296	0.97
292_A	296_L	1.292	0.97
348_E	416_R	1.287	0.97
383_K	386_D	1.281	0.97
8_I	175_N	1.281	0.97
22_Q	64_N	1.278	0.97
314_K	320_S	1.275	0.97
254_K	327_S	1.273	0.97
287_D	291_E	1.259	0.96
76_G	105_P	1.259	0.96
90_T	255_E	1.257	0.96
125_E	132_V	1.256	0.96
181_A	224_I	1.256	0.96
60_M	63_V	1.252	0.96
94_V	259_T	1.252	0.96
235_V	430_L	1.234	0.96
55_R	178_P	1.226	0.96
73_A	140_I	1.226	0.96
375_A	400_N	1.225	0.96
22_Q	57_D	1.222	0.96
106_V	279_M	1.222	0.96
6_I	38_A	1.221	0.96
22_Q	26_N	1.214	0.95
215_A	219_K	1.210	0.95
395_V	411_V	1.209	0.95
254_K	258_D	1.205	0.95
185_M	225_G	1.201	0.95
331_Q	375_A	1.199	0.95
38_A	164_L	1.194	0.95
96_A	148_V	1.193	0.95
331_Q	398_Y	1.186	0.95
74_I	78_K	1.176	0.95
376_V	397_L	1.165	0.94
280_V	292_A	1.163	0.94
250_A	254_K	1.162	0.94
172_G	175_N	1.161	0.94
62_M	186_S	1.156	0.94
306_L	310_K	1.155	0.94
335_Q	398_Y	1.146	0.94
16_L	41_L	1.142	0.94
78_K	194_D	1.140	0.94
52_D	227_N	1.130	0.93
304_K	307_E	1.127	0.93
195_A	231_Q	1.126	0.93
294_A	297_E	1.120	0.93
270_E	293_R	1.113	0.93
204_A	350_V	1.112	0.93
345_V	387_K	1.107	0.93
259_T	265_P	1.104	0.92
247_I	380_L	1.104	0.92
202_T	428_H	1.099	0.92
12_N	175_N	1.093	0.92
143_V	149_A	1.088	0.92
60_M	64_N	1.087	0.92
330_P	375_A	1.087	0.92
251_L	332_A	1.084	0.92
49_D	178_P	1.080	0.92
354_I	378_I	1.080	0.92
22_Q	61_A	1.078	0.92
357_A	407_V	1.061	0.91
226_N	231_Q	1.048	0.90
373_D	401_R	1.046	0.90
92_T	108_K	1.045	0.90
273_L	293_R	1.039	0.90
238_D	424_P	1.027	0.89
60_M	228_V	1.026	0.89
379_M	396_T	1.026	0.89
334_Y	399_A	1.025	0.89
409_A	413_D	1.024	0.89
222_V	234_A	1.019	0.89
404_V	407_V	1.018	0.89
130_F	316_Q	1.017	0.89
150_V	312_F	1.015	0.89
18_T	60_M	1.015	0.89
334_Y	402_E	1.012	0.89
405_D	408_I	1.012	0.89
91_T	272_V	1.007	0.89
259_T	264_G	1.000	0.88
204_A	240_S	0.994	0.88
27_G	30_D	0.993	0.88
67_E	136_K	0.987	0.87
424_P	428_H	0.984	0.87
138_E	142_L	0.984	0.87
128_M	319_D	0.983	0.87
98_L	305_A	0.982	0.87
231_Q	284_K	0.978	0.87
340_A	343_A	0.977	0.87
246_A	251_L	0.977	0.87
91_T	271_L	0.977	0.87
353_E	414_N	0.975	0.87
79_V	283_A	0.974	0.87
360_L	410_K	0.973	0.87
49_D	55_R	0.971	0.87
357_A	411_V	0.970	0.87
233_M	278_Q	0.966	0.86
17_T	20_E	0.964	0.86
336_I	405_D	0.963	0.86
233_M	282_L	0.961	0.86
148_V	312_F	0.961	0.86
99_V	283_A	0.960	0.86
341_K	390_K	0.956	0.86
342_E	417_I	0.953	0.86
266_E	270_E	0.945	0.85
341_K	392_E	0.937	0.85
381_R	393_P	0.937	0.85
24_F	45_I	0.935	0.85
98_L	101_A	0.933	0.84
277_S	296_L	0.932	0.84
107_A	196_I	0.932	0.84
204_A	348_E	0.932	0.84
286_A	295_K	0.932	0.84
193_A	196_I	0.932	0.84
71_L	78_K	0.927	0.84
269_H	273_L	0.924	0.84
235_V	274_T	0.923	0.84
108_K	196_I	0.922	0.84
261_K	303_G	0.921	0.84
95_L	272_V	0.921	0.84
250_A	330_P	0.920	0.84
10_K	54_E	0.918	0.83
121_I	196_I	0.918	0.83
306_L	320_S	0.918	0.83
109_M	193_A	0.915	0.83
35_D	368_K	0.911	0.83
281_V	286_A	0.907	0.83
91_T	275_L	0.905	0.83
319_D	328_K	0.904	0.82
63_V	228_V	0.902	0.82
195_A	282_L	0.899	0.82
313_L	318_G	0.897	0.82
11_Q	175_N	0.897	0.82
254_K	379_M	0.895	0.82
202_T	211_E	0.891	0.82
25_V	160_A	0.891	0.82
360_L	366_A	0.889	0.81
196_I	230_R	0.887	0.81
109_M	153_Q	0.886	0.81
342_E	390_K	0.884	0.81
238_D	241_Q	0.883	0.81
79_V	104_V	0.883	0.81
211_E	428_H	0.882	0.81
332_A	375_A	0.881	0.81
102_L	295_K	0.881	0.81
105_P	147_K	0.879	0.81
16_L	21_I	0.879	0.81
240_S	348_E	0.876	0.80
277_S	289_L	0.876	0.80
250_A	375_A	0.872	0.80
237_S	271_L	0.869	0.80
121_I	130_F	0.860	0.79
345_V	418_A	0.855	0.79
241_Q	384_V	0.854	0.79
77_I	195_A	0.853	0.79
93_L	97_P	0.851	0.78
336_I	402_E	0.847	0.78
387_K	421_A	0.844	0.78
244_G	255_E	0.842	0.78
96_A	312_F	0.840	0.78
4_V	172_G	0.839	0.77
235_V	278_Q	0.839	0.77
356_V	360_L	0.839	0.77
76_G	194_D	0.834	0.77
137_D	141_K	0.832	0.77
57_D	60_M	0.832	0.77
281_V	292_A	0.830	0.77
283_A	286_A	0.824	0.76
250_A	329_L	0.823	0.76
49_D	176_S	0.822	0.76
370_D	374_L	0.822	0.76
38_A	41_L	0.821	0.76
359_M	366_A	0.813	0.75
146_D	311_D	0.812	0.75
211_E	214_A	0.812	0.75
104_V	280_V	0.803	0.74
185_M	224_I	0.800	0.74
272_V	276_G	0.799	0.74
185_M	198_L	0.798	0.74
21_I	61_A	0.797	0.74
201_K	271_L	0.796	0.74
21_I	25_V	0.794	0.73
67_E	155_G	0.788	0.73
274_T	278_Q	0.785	0.73
8_I	11_Q	0.783	0.72
259_T	268_L	0.782	0.72
211_E	429_T	0.782	0.72
10_K	50_M	0.781	0.72
363_A	376_V	0.778	0.72
90_T	383_K	0.774	0.72
23_F	27_G	0.773	0.71
382_K	386_D	0.773	0.71
346_V	415_I	0.772	0.71
343_A	416_R	0.771	0.71
121_I	312_F	0.771	0.71
269_H	300_M	0.769	0.71
25_V	29_T	0.767	0.71
274_T	293_R	0.767	0.71
295_K	299_V	0.765	0.71
95_L	275_L	0.764	0.71
180_I	208_M	0.764	0.71
346_V	384_V	0.762	0.70
40_A	172_G	0.762	0.70
340_A	391_G	0.760	0.70
75_E	78_K	0.760	0.70
99_V	276_G	0.760	0.70
247_I	358_A	0.758	0.70
98_L	300_M	0.757	0.70
104_V	283_A	0.757	0.70
52_D	216_E	0.752	0.69
304_K	308_K	0.749	0.69
336_I	404_V	0.749	0.69
212_E	215_A	0.746	0.69
90_T	246_A	0.744	0.69
226_N	229_G	0.744	0.69
406_E	409_A	0.743	0.68
21_I	50_M	0.740	0.68
108_K	193_A	0.740	0.68
107_A	272_V	0.738	0.68
11_Q	46_F	0.738	0.68
126_A	374_L	0.737	0.68
31_G	163_K	0.736	0.68
307_E	310_K	0.734	0.68
338_V	412_Y	0.731	0.67
331_Q	335_Q	0.730	0.67
99_V	104_V	0.730	0.67
98_L	292_A	0.728	0.67
209_K	213_D	0.727	0.67
286_A	291_E	0.724	0.66
375_A	398_Y	0.723	0.66
332_A	398_Y	0.722	0.66
289_L	292_A	0.722	0.66
28_Y	167_L	0.721	0.66
246_A	254_K	0.719	0.66
218_A	234_A	0.719	0.66
100_A	308_K	0.716	0.66
181_A	185_M	0.716	0.66
254_K	329_L	0.716	0.66
384_V	424_P	0.716	0.66
133_E	154_S	0.715	0.65
387_K	417_I	0.710	0.65
94_V	256_A	0.708	0.65
195_A	283_A	0.708	0.65
55_R	58_L	0.706	0.65
382_K	388_V	0.706	0.65
29_T	61_A	0.705	0.64
240_S	428_H	0.704	0.64
94_V	272_V	0.703	0.64
6_I	23_F	0.702	0.64
247_I	378_I	0.702	0.64
277_S	293_R	0.701	0.64
277_S	281_V	0.699	0.64
155_G	162_K	0.698	0.64
47_F	55_R	0.698	0.64
46_F	175_N	0.698	0.64
266_E	269_H	0.698	0.64
71_L	139_F	0.695	0.63
344_G	417_I	0.695	0.63
73_A	144_N	0.694	0.63
291_E	294_A	0.693	0.63
200_V	234_A	0.692	0.63
63_V	230_R	0.689	0.63
273_L	277_S	0.687	0.62
337_D	381_R	0.687	0.62
393_P	396_T	0.687	0.62
215_A	236_I	0.687	0.62
397_L	411_V	0.685	0.62
273_L	297_E	0.684	0.62
339_P	412_Y	0.683	0.62
45_I	58_L	0.683	0.62
237_S	274_T	0.682	0.62
339_P	391_G	0.681	0.62
271_L	426_L	0.680	0.62
411_V	415_I	0.678	0.61
246_A	255_E	0.678	0.61
333_A	402_E	0.677	0.61
264_G	269_H	0.676	0.61
94_V	98_L	0.676	0.61
397_L	404_V	0.675	0.61
29_T	160_A	0.675	0.61
108_K	121_I	0.674	0.61
74_I	105_P	0.674	0.61
101_A	302_N	0.673	0.61
339_P	390_K	0.673	0.61
353_E	413_D	0.673	0.61
198_L	232_T	0.672	0.61
177_I	216_E	0.672	0.61
143_V	192_G	0.672	0.61
254_K	398_Y	0.672	0.61
278_Q	289_L	0.671	0.61
274_T	277_S	0.671	0.61
270_E	274_T	0.670	0.60
339_P	392_E	0.670	0.60
240_S	424_P	0.669	0.60
310_K	320_S	0.668	0.60
36_Y	39_S	0.667	0.60
126_A	331_Q	0.666	0.60
235_V	275_L	0.666	0.60
107_A	312_F	0.664	0.60
291_E	295_K	0.663	0.60
38_A	167_L	0.662	0.60
334_Y	404_V	0.662	0.60
34_P	39_S	0.661	0.59
340_A	417_I	0.658	0.59
140_I	144_N	0.658	0.59
211_E	236_I	0.657	0.59
367_T	371_E	0.656	0.59
242_P	246_A	0.656	0.59
134_L	316_Q	0.654	0.59
9_K	17_T	0.653	0.58
399_A	404_V	0.652	0.58
101_A	308_K	0.651	0.58
25_V	232_T	0.650	0.58
68_T	230_R	0.649	0.58
45_I	50_M	0.648	0.58
56_A	60_M	0.647	0.58
143_V	191_A	0.647	0.58
96_A	214_A	0.646	0.58
107_A	143_V	0.646	0.58
245_F	379_M	0.645	0.58
28_Y	163_K	0.645	0.58
143_V	157_L	0.642	0.57
350_V	414_N	0.641	0.57
395_V	415_I	0.640	0.57
349_I	384_V	0.637	0.57
153_Q	157_L	0.637	0.57
52_D	220_A	0.636	0.57
238_D	428_H	0.635	0.56
380_L	383_K	0.632	0.56
6_I	16_L	0.632	0.56
92_T	184_I	0.631	0.56
37_Q	43_M	0.631	0.56
109_M	221_M	0.628	0.56
131_H	134_L	0.627	0.55
354_I	407_V	0.627	0.55
109_M	196_I	0.626	0.55
71_L	74_I	0.624	0.55
254_K	331_Q	0.624	0.55
72_S	78_K	0.622	0.55
27_G	33_I	0.621	0.55
109_M	151_I	0.618	0.54
96_A	150_V	0.617	0.54
68_T	158_T	0.617	0.54
34_P	47_F	0.614	0.54
134_L	138_E	0.613	0.54
259_T	267_D	0.613	0.54
52_D	56_A	0.612	0.54
69_I	363_A	0.612	0.54
240_S	384_V	0.612	0.54
298_E	301_K	0.611	0.54
29_T	158_T	0.611	0.54
276_G	279_M	0.610	0.53
87_V	116_H	0.608	0.53
102_L	312_F	0.607	0.53
209_K	214_A	0.604	0.53
273_L	300_M	0.603	0.53
121_I	152_G	0.603	0.53
74_I	144_N	0.602	0.52
294_A	298_E	0.602	0.52
352_D	356_V	0.601	0.52
388_V	394_L	0.600	0.52
401_R	404_V	0.599	0.52
107_A	191_A	0.598	0.52
154_S	240_S	0.598	0.52
75_E	105_P	0.597	0.52
39_S	42_A	0.597	0.52
258_D	261_K	0.596	0.52
245_F	381_R	0.596	0.52
389_E	417_I	0.594	0.52
408_I	411_V	0.591	0.51
4_V	366_A	0.589	0.51
150_V	363_A	0.587	0.51
25_V	28_Y	0.587	0.51
134_L	151_I	0.586	0.51
110_S	121_I	0.586	0.51
4_V	8_I	0.586	0.51
107_A	230_R	0.583	0.50
71_L	193_A	0.583	0.50
281_V	296_L	0.582	0.50
58_L	182_S	0.581	0.50
19_E	22_Q	0.581	0.50
145_R	311_D	0.580	0.50
19_E	23_F	0.577	0.49
53_R	227_N	0.577	0.49
28_Y	32_S	0.576	0.49
102_L	296_L	0.574	0.49
29_T	163_K	0.573	0.49
108_K	191_A	0.572	0.49
5_D	356_V	0.572	0.49
191_A	196_I	0.572	0.49
13_G	47_F	0.572	0.49
112_R	125_E	0.569	0.49
372_I	376_V	0.567	0.48
257_I	306_L	0.567	0.48
277_S	286_A	0.567	0.48
94_V	309_F	0.567	0.48
336_I	399_A	0.566	0.48
380_L	386_D	0.565	0.48
7_I	50_M	0.565	0.48
116_H	201_K	0.564	0.48
98_L	273_L	0.563	0.48
345_V	420_E	0.561	0.48
208_M	214_A	0.560	0.47
327_S	331_Q	0.559	0.47
67_E	392_E	0.558	0.47
158_T	228_V	0.557	0.47
387_K	405_D	0.557	0.47
289_L	293_R	0.557	0.47
90_T	267_D	0.556	0.47
124_L	253_V	0.555	0.47
130_F	312_F	0.555	0.47
282_L	363_A	0.555	0.47
394_L	415_I	0.555	0.47
204_A	352_D	0.553	0.47
197_V	280_V	0.553	0.47
21_I	270_E	0.553	0.47
343_A	387_K	0.551	0.46
25_V	164_L	0.549	0.46
387_K	419_A	0.549	0.46
92_T	109_M	0.549	0.46
241_Q	376_V	0.547	0.46
360_L	406_E	0.546	0.46
250_A	292_A	0.545	0.46
62_M	164_L	0.544	0.46
108_K	221_M	0.544	0.46
151_I	191_A	0.543	0.45
46_F	172_G	0.541	0.45
95_L	296_L	0.540	0.45
141_K	144_N	0.539	0.45
419_A	427_I	0.539	0.45
347_S	416_R	0.539	0.45
214_A	219_K	0.536	0.45
52_D	178_P	0.535	0.44
342_E	387_K	0.535	0.44
147_K	308_K	0.535	0.44
179_L	182_S	0.535	0.44
71_L	224_I	0.534	0.44
397_L	408_I	0.534	0.44
127_I	309_F	0.533	0.44
275_L	282_L	0.532	0.44
300_M	416_R	0.532	0.44
309_F	313_L	0.532	0.44
402_E	405_D	0.532	0.44
264_G	267_D	0.531	0.44
416_R	421_A	0.530	0.44
37_Q	40_A	0.530	0.44
119_G	122_D	0.529	0.44
127_I	312_F	0.529	0.44
95_L	98_L	0.529	0.44
254_K	330_P	0.529	0.44
132_V	391_G	0.529	0.44
156_N	162_K	0.527	0.44
141_K	387_K	0.527	0.44
103_D	285_K	0.527	0.44
18_T	61_A	0.526	0.43
28_Y	368_K	0.526	0.43
216_E	220_A	0.525	0.43
413_D	425_K	0.524	0.43
126_A	250_A	0.524	0.43
260_L	305_A	0.524	0.43
418_A	421_A	0.524	0.43
380_L	395_V	0.523	0.43
108_K	256_A	0.522	0.43
77_I	284_K	0.522	0.43
130_F	149_A	0.522	0.43
423_A	427_I	0.521	0.43
15_E	18_T	0.521	0.43
158_T	363_A	0.520	0.43
35_D	39_S	0.520	0.43
138_E	145_R	0.520	0.43
62_M	161_D	0.520	0.43
94_V	276_G	0.518	0.42
108_K	368_K	0.516	0.42
425_K	428_H	0.516	0.42
245_F	266_E	0.516	0.42
167_L	368_K	0.515	0.42
123_K	179_L	0.515	0.42
72_S	76_G	0.515	0.42
90_T	256_A	0.514	0.42
10_K	49_D	0.514	0.42
121_I	151_I	0.512	0.42
223_R	227_N	0.512	0.42
101_A	304_K	0.512	0.42
197_V	282_L	0.512	0.42
16_L	54_E	0.511	0.42
287_D	294_A	0.510	0.42
338_V	408_I	0.509	0.41
92_T	363_A	0.509	0.41
164_L	167_L	0.509	0.41
204_A	351_A	0.508	0.41
272_V	426_L	0.507	0.41
146_D	312_F	0.506	0.41
193_A	230_R	0.506	0.41
89_D	179_L	0.505	0.41
107_A	221_M	0.504	0.41
96_A	151_I	0.504	0.41
311_D	314_K	0.503	0.41
258_D	327_S	0.502	0.41
12_N	48_Q	0.501	0.40
161_D	377_G	0.501	0.40
222_V	232_T	0.501	0.40
185_M	355_G	0.501	0.40
113_G	170_V	0.501	0.40
336_I	403_N	0.501	0.40
291_E	304_K	0.500	0.40
202_T	238_D	0.500	0.40
56_A	220_A	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3h5qA	2	1	100	0.271	Contact Map
1brwA	2	0.9977	100	0.272	Contact Map
4eadA	2	1	100	0.282	Contact Map
2dsjA	2	0.9769	100	0.284	Contact Map
1uouA	2	0.9769	100	0.297	Contact Map
4ga6A	2	0.9307	100	0.385	Contact Map
1vquA	2	0.6905	100	0.601	Contact Map
2elcA	4	0.6859	100	0.613	Contact Map
4giuA	2	0.6882	100	0.613	Contact Map
1khdA	2	0.6744	100	0.618	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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