GREMLIN Database
PRKA - Protein PrkA
UniProt: P39134 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 631 (605)
Sequences: 488 (169)
Seq/√Len: 6.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
614_N617_S9.6331.00
429_S617_S8.9551.00
327_S382_D7.6791.00
429_S614_N7.4761.00
167_S170_N6.2961.00
29_I36_V5.9481.00
44_V84_F5.2170.99
313_S410_D5.0780.99
111_L362_T4.7000.98
147_P151_R4.6590.98
38_Q46_N4.6260.98
62_Y67_R3.6520.93
61_K67_R3.5930.92
20_E134_K3.5090.91
325_K328_E3.4090.90
167_S429_S3.2880.88
276_F410_D3.0940.85
381_Y404_E3.0760.84
64_F67_R3.0690.84
130_V192_F3.0660.84
362_T623_K2.8270.79
173_R177_E2.8120.78
63_S67_R2.7920.78
165_S250_M2.6930.75
61_K64_F2.6770.75
181_R184_D2.6720.75
167_S614_N2.6580.74
383_G388_G2.6130.73
132_A135_G2.5880.72
167_S617_S2.5750.72
62_Y80_V2.5300.70
136_C167_S2.4720.68
346_H614_N2.4680.68
48_I80_V2.3810.65
276_F313_S2.2760.62
136_C170_N2.2650.61
105_S410_D2.2280.60
503_C524_M2.1670.58
387_E607_L2.1510.57
151_R155_Y2.1430.57
121_A365_K2.1250.56
67_R353_K2.1250.56
216_L479_A2.1180.56
360_I460_F2.1090.56
388_G567_L2.0680.54
105_S351_T2.0300.53
362_T417_R2.0290.52
326_V382_D2.0190.52
321_P333_Y2.0150.52
499_V618_A2.0120.52
133_I185_V2.0020.51
149_H605_A1.9350.49
528_E542_R1.9060.48
152_D155_Y1.8940.47
269_S410_D1.8760.47
137_P264_L1.8580.46
255_E310_A1.8310.45
254_Q313_S1.8280.45
147_P150_L1.8020.44
218_G255_E1.7760.43
549_I553_A1.7660.43
360_I612_G1.7640.42
510_D514_G1.7510.42
8_E12_E1.7340.41
476_V625_V1.7310.41
28_E32_E1.7280.41
593_D596_Q1.7180.41
140_E170_N1.7170.41
418_I435_V1.7150.41
25_D356_A1.7150.41
497_D501_A1.7090.40
175_E196_K1.7050.40
356_A361_L1.7050.40
375_V378_M1.7020.40
61_K66_D1.6940.40
400_E611_H1.6780.39
35_M46_N1.6740.39
90_R161_R1.6700.39
318_M388_G1.6590.39
11_R15_Q1.6430.38
413_Y442_G1.6380.38
54_E63_S1.6220.37
8_E518_N1.6180.37
132_A188_E1.6160.37
318_M410_D1.6100.37
383_G389_Y1.6000.37
296_E510_D1.5960.36
58_G62_Y1.5790.36
139_H277_K1.5760.36
216_L273_E1.5750.36
318_M486_E1.5750.36
254_Q410_D1.5740.36
365_K407_S1.5740.36
25_D557_K1.5690.35
362_T610_E1.5600.35
201_G234_P1.5450.35
360_I380_L1.5420.34
290_I384_E1.5410.34
322_Y329_E1.5370.34
170_N429_S1.5340.34
491_L622_L1.5210.34
313_S351_T1.5000.33
245_K289_L1.5000.33
28_E334_E1.4980.33
161_R392_V1.4810.32
105_S313_S1.4790.32
121_A557_K1.4770.32
22_T496_L1.4730.32
102_G108_K1.4700.32
68_E132_A1.4690.32
128_G151_R1.4550.32
351_T505_K1.4530.31
292_A484_Y1.4510.31
90_R459_N1.4500.31
156_R362_T1.4480.31
329_E363_R1.4180.30
194_E281_F1.4170.30
12_E605_A1.4120.30
62_Y66_D1.4120.30
256_M326_V1.4060.30
360_I558_R1.4030.30
207_D273_E1.4000.30
289_L359_S1.3990.30
160_I170_N1.3910.29
121_A605_A1.3860.29
205_P333_Y1.3860.29
357_M378_M1.3820.29
9_K13_E1.3790.29
152_D461_I1.3780.29
234_P310_A1.3650.29
92_D283_L1.3590.28
137_P541_F1.3570.28
264_L310_A1.3530.28
119_L200_I1.3510.28
409_I517_M1.3510.28
141_D160_I1.3490.28
168_P264_L1.3470.28
170_N614_N1.3450.28
46_N362_T1.3440.28
430_I457_Y1.3320.28
58_G402_N1.3280.28
420_S461_I1.3200.27
9_K12_E1.3180.27
330_E334_E1.3180.27
205_P321_P1.3120.27
48_I62_Y1.3110.27
515_E590_K1.3080.27
19_W157_E1.3030.27
242_E461_I1.2820.26
377_K404_E1.2820.26
58_G394_V1.2750.26
27_L292_A1.2740.26
11_R409_I1.2730.26
362_T457_Y1.2720.26
256_M477_Q1.2680.26
379_R384_E1.2610.26
150_L155_Y1.2590.25
250_M352_L1.2590.25
62_Y364_L1.2500.25
365_K403_D1.2440.25
99_L257_L1.2420.25
244_N478_K1.2400.25
441_E607_L1.2360.25
247_N287_D1.2350.25
409_I501_A1.2350.25
67_R289_L1.2320.25
264_L541_F1.2280.25
280_R317_V1.2260.25
350_H353_K1.2230.24
380_L517_M1.2200.24
128_G277_K1.2190.24
550_S553_A1.2170.24
141_D617_S1.2160.24
532_G617_S1.2110.24
532_G614_N1.2100.24
81_E121_A1.2090.24
334_E560_D1.2090.24
147_P152_D1.2030.24
269_S313_S1.2000.24
274_G359_S1.1900.24
597_L601_N1.1870.23
85_H179_G1.1840.23
248_R287_D1.1820.23
396_D607_L1.1800.23
508_L607_L1.1800.23
225_I239_F1.1760.23
205_P412_R1.1760.23
201_G380_L1.1680.23
545_I597_L1.1650.23
63_S66_D1.1620.23
90_R475_E1.1570.23
115_L118_G1.1560.23
207_D216_L1.1560.23
523_L584_K1.1540.23
558_R605_A1.1520.23
594_E598_K1.1430.22
405_G495_Y1.1430.22
314_R405_G1.1430.22
142_P405_G1.1430.22
295_N405_G1.1430.22
349_P405_G1.1430.22
204_S311_L1.1230.22
295_N495_Y1.1230.22
142_P295_N1.1230.22
349_P495_Y1.1230.22
295_N314_R1.1230.22
142_P495_Y1.1230.22
295_N349_P1.1230.22
314_R495_Y1.1230.22
314_R349_P1.1230.22
142_P314_R1.1230.22
142_P349_P1.1230.22
8_E156_R1.1190.22
211_Q264_L1.1190.22
151_R199_G1.1180.22
16_R560_D1.1160.22
257_L411_P1.1150.22
16_R28_E1.1090.21
390_N438_S1.1080.21
212_D309_E1.1060.21
222_F313_S1.1060.21
299_Y303_I1.1010.21
289_L292_A1.1000.21
141_D614_N1.0980.21
501_A574_K1.0960.21
140_E617_S1.0940.21
24_A615_S1.0940.21
232_S277_K1.0900.21
616_T620_E1.0860.21
165_S341_D1.0840.21
303_I311_L1.0820.21
104_V211_Q1.0820.21
381_Y544_E1.0820.21
61_K73_E1.0810.21
154_F339_E1.0810.21
173_R179_G1.0800.21
351_T410_D1.0790.21
103_P108_K1.0780.21
120_E193_S1.0770.21
510_D515_E1.0720.20
14_E362_T1.0710.20
105_S269_S1.0610.20
163_E166_L1.0600.20
66_D152_D1.0600.20
431_N504_N1.0580.20
48_I396_D1.0540.20
12_E250_M1.0520.20
140_E144_H1.0470.20
459_N463_A1.0470.20
274_G544_E1.0450.20
431_N574_K1.0450.20
202_T411_P1.0450.20
145_L185_V1.0430.20
292_A337_I1.0430.20
20_E25_D1.0410.20
254_Q269_S1.0400.20
18_K391_S1.0400.20
364_L541_F1.0390.20
92_D133_I1.0390.20
139_H245_K1.0390.20
149_H360_I1.0370.20
431_N486_E1.0360.20
239_F420_S1.0350.20
70_F521_E1.0320.19
96_R128_G1.0320.19
160_I389_Y1.0310.19
393_D593_D1.0310.19
31_K154_F1.0300.19
382_D568_R1.0290.19
508_L539_K1.0260.19
189_R281_F1.0250.19
210_S243_L1.0250.19
19_W263_F1.0240.19
41_H231_E1.0230.19
234_P255_E1.0230.19
170_N617_S1.0230.19
252_E293_H1.0210.19
166_L362_T1.0200.19
237_Y378_M1.0160.19
13_E18_K1.0140.19
222_F410_D1.0140.19
347_I565_E1.0100.19
141_D429_S1.0070.19
387_E390_N1.0070.19
362_T514_G1.0070.19
367_P547_I1.0040.19
207_D264_L1.0020.19
208_P386_V1.0020.19
459_N601_N1.0000.19
431_N616_T0.9910.19
267_L356_A0.9900.19
46_N353_K0.9900.19
13_E16_R0.9900.19
147_P155_Y0.9890.18
520_D525_R0.9880.18
12_E148_H0.9830.18
193_S439_L0.9830.18
59_R63_S0.9820.18
390_N532_G0.9800.18
58_G61_K0.9710.18
94_R246_A0.9710.18
401_Y425_K0.9650.18
236_A267_L0.9650.18
278_A292_A0.9640.18
140_E205_P0.9620.18
136_C144_H0.9600.18
221_D302_F0.9600.18
524_M552_Y0.9580.18
71_G102_G0.9580.18
282_A400_E0.9570.18
427_M557_K0.9540.18
276_F359_S0.9500.18
69_L86_P0.9490.18
87_A104_V0.9490.18
475_E523_L0.9480.18
180_G302_F0.9460.18
254_Q276_F0.9460.18
481_V624_Y0.9460.18
198_T246_A0.9460.18
161_R341_D0.9460.18
16_R25_D0.9440.17
362_T430_I0.9430.17
388_G485_E0.9430.17
39_S42_S0.9420.17
263_F277_K0.9420.17
32_E455_E0.9380.17
267_L311_L0.9370.17
430_I475_E0.9360.17
267_L329_E0.9360.17
205_P332_I0.9360.17
34_P157_E0.9350.17
607_L618_A0.9330.17
252_E296_E0.9320.17
57_D341_D0.9310.17
576_F600_V0.9300.17
218_G310_A0.9290.17
12_E149_H0.9280.17
28_E156_R0.9270.17
189_R263_F0.9270.17
330_E594_E0.9270.17
34_P128_G0.9250.17
105_S357_M0.9240.17
262_K434_D0.9240.17
225_I390_N0.9190.17
441_E514_G0.9130.17
109_S377_K0.9120.17
96_R209_K0.9100.17
257_L294_T0.9070.17
22_T558_R0.9060.17
87_A298_E0.9050.17
79_L338_A0.9040.17
116_K293_H0.9030.17
315_I484_Y0.9020.17
42_S435_V0.8990.17
173_R185_V0.8960.16
579_L596_Q0.8960.16
285_S418_I0.8940.16
606_R610_E0.8930.16
168_P255_E0.8930.16
325_K452_E0.8930.16
88_A234_P0.8910.16
48_I607_L0.8900.16
186_K457_Y0.8890.16
21_G163_E0.8880.16
75_S509_R0.8870.16
318_M590_K0.8860.16
483_S606_R0.8840.16
473_K625_V0.8830.16
108_K405_G0.8830.16
280_R593_D0.8820.16
102_G363_R0.8790.16
331_R598_K0.8780.16
120_E410_D0.8780.16
209_K299_Y0.8770.16
33_N148_H0.8740.16
274_G557_K0.8730.16
168_P309_E0.8710.16
571_I621_L0.8700.16
98_L320_V0.8690.16
374_L589_T0.8680.16
362_T501_A0.8650.16
108_K495_Y0.8650.16
108_K295_N0.8650.16
108_K142_P0.8650.16
108_K314_R0.8650.16
108_K349_P0.8650.16
327_S461_I0.8640.16
12_E459_N0.8610.16
247_N322_Y0.8610.16
255_E272_Q0.8600.16
404_E544_E0.8570.16
488_A571_I0.8550.16
413_Y543_E0.8540.16
299_Y307_K0.8540.16
117_K334_E0.8490.15
351_T354_V0.8490.15
351_T432_S0.8420.15
26_Y75_S0.8390.15
252_E333_Y0.8380.15
168_P310_A0.8380.15
97_I290_I0.8350.15
32_E334_E0.8350.15
59_R320_V0.8320.15
166_L287_D0.8320.15
18_K565_E0.8310.15
424_R511_P0.8290.15
578_D596_Q0.8250.15
350_H478_K0.8250.15
256_M262_K0.8250.15
271_T418_I0.8240.15
178_Y331_R0.8240.15
510_D513_T0.8230.15
341_D515_E0.8230.15
254_Q359_S0.8220.15
444_D515_E0.8210.15
339_E569_E0.8200.15
41_H488_A0.8180.15
210_S270_L0.8170.15
242_E358_F0.8170.15
121_A148_H0.8170.15
534_S571_I0.8160.15
301_S599_K0.8140.15
12_E452_E0.8130.15
33_N540_A0.8130.15
460_F569_E0.8120.15
273_E544_E0.8100.15
378_M557_K0.8100.15
304_S509_R0.8080.15
147_P329_E0.8080.15
475_E486_E0.8060.15
598_K605_A0.8050.15
241_G520_D0.8030.15
342_V383_G0.8030.15
364_L501_A0.8020.15
78_R460_F0.8010.15
96_R331_R0.8000.15
341_D418_I0.8000.15
121_A334_E0.7990.15
109_S322_Y0.7980.15
196_K360_I0.7980.15
360_I452_E0.7960.14
15_Q595_Q0.7950.14
444_D486_E0.7940.14
427_M560_D0.7910.14
111_L391_S0.7910.14
243_L262_K0.7880.14
269_S320_V0.7880.14
236_A255_E0.7870.14
186_K362_T0.7860.14
88_A310_A0.7860.14
190_I454_R0.7860.14
34_P103_P0.7850.14
167_S371_D0.7840.14
150_L153_D0.7830.14
244_N593_D0.7820.14
304_S499_V0.7820.14
105_S254_Q0.7810.14
74_E334_E0.7790.14
579_L616_T0.7790.14
28_E362_T0.7780.14
9_K18_K0.7780.14
53_I560_D0.7780.14
40_A520_D0.7760.14
152_D394_V0.7760.14
405_G408_G0.7740.14
25_D250_M0.7730.14
242_E411_P0.7720.14
74_E398_K0.7700.14
84_F472_A0.7690.14
431_N475_E0.7670.14
120_E147_P0.7660.14
74_E356_A0.7660.14
333_Y572_Q0.7660.14
24_A343_A0.7650.14
211_Q310_A0.7640.14
202_T257_L0.7640.14
177_E403_D0.7640.14
199_G329_E0.7640.14
285_S432_S0.7620.14
244_N491_L0.7620.14
223_S438_S0.7610.14
327_S352_L0.7590.14
50_D462_S0.7590.14
103_P408_G0.7580.14
257_L263_F0.7570.14
16_R35_M0.7560.14
142_P408_G0.7550.14
295_N408_G0.7550.14
349_P408_G0.7550.14
314_R408_G0.7550.14
408_G495_Y0.7550.14
351_T459_N0.7540.14
474_K484_Y0.7520.14
65_F102_G0.7520.14
266_H313_S0.7510.14
38_Q265_W0.7510.14
137_P168_P0.7510.14
457_Y539_K0.7490.14
237_Y251_M0.7490.14
271_T289_L0.7490.14
87_A137_P0.7490.14
285_S410_D0.7480.14
92_D285_S0.7460.14
98_L221_D0.7460.14
444_D454_R0.7450.14
40_A290_I0.7450.14
199_G322_Y0.7440.14
449_I569_E0.7420.13
194_E578_D0.7420.13
373_D463_A0.7420.13
250_M594_E0.7420.13
149_H327_S0.7410.13
33_N304_S0.7400.13
79_L217_T0.7400.13
290_I382_D0.7390.13
290_I328_E0.7380.13
389_Y394_V0.7360.13
558_R594_E0.7350.13
430_I436_L0.7350.13
266_H410_D0.7330.13
149_H454_R0.7330.13
417_R554_R0.7320.13
109_S128_G0.7320.13
578_D616_T0.7300.13
28_E63_S0.7290.13
96_R299_Y0.7290.13
68_E135_G0.7280.13
179_G250_M0.7280.13
443_L499_V0.7270.13
622_L626_G0.7260.13
30_I304_S0.7220.13
148_H343_A0.7200.13
15_Q331_R0.7180.13
24_A360_I0.7180.13
491_L593_D0.7180.13
87_A381_Y0.7170.13
44_V48_I0.7150.13
120_E332_I0.7150.13
59_R362_T0.7150.13
337_I580_K0.7130.13
24_A605_A0.7130.13
165_S418_I0.7120.13
139_H330_E0.7110.13
524_M535_E0.7110.13
362_T560_D0.7110.13
101_M515_E0.7090.13
264_L273_E0.7090.13
433_L440_K0.7070.13
38_Q42_S0.7060.13
490_T499_V0.7060.13
501_A593_D0.7060.13
137_P216_L0.7050.13
530_Q577_A0.7050.13
409_I452_E0.7050.13
17_L150_L0.7050.13
61_K74_E0.7050.13
41_H417_R0.7020.13
608_I615_S0.7000.13
417_R442_G0.6970.13
260_D311_L0.6960.13
186_K496_L0.6960.13
582_V585_I0.6950.13
276_F285_S0.6950.13
414_V449_I0.6940.13
121_A178_Y0.6940.13
32_E75_S0.6930.13
201_G228_Y0.6910.13
486_E574_K0.6910.13
282_A545_I0.6890.13
57_D148_H0.6890.13
34_P147_P0.6880.13
206_S286_A0.6880.13
64_F201_G0.6880.13
427_M605_A0.6870.13
221_D238_R0.6860.13
143_L319_P0.6850.12
203_F299_Y0.6830.12
203_F277_K0.6820.12
492_M518_N0.6810.12
501_A509_R0.6810.12
132_A237_Y0.6810.12
384_E438_S0.6800.12
116_K288_E0.6790.12
96_R294_T0.6790.12
354_V432_S0.6780.12
79_L250_M0.6780.12
431_N547_I0.6770.12
92_D418_I0.6760.12
515_E624_Y0.6760.12
109_S310_A0.6760.12
153_D160_I0.6750.12
410_D447_P0.6750.12
211_Q216_L0.6750.12
228_Y610_E0.6740.12
164_G189_R0.6740.12
330_E597_L0.6740.12
103_P109_S0.6730.12
31_K100_L0.6730.12
148_H152_D0.6720.12
246_A361_L0.6710.12
342_V418_I0.6710.12
298_E510_D0.6700.12
29_I407_S0.6700.12
234_P612_G0.6690.12
107_G358_F0.6680.12
603_V621_L0.6670.12
215_D292_A0.6670.12
221_D231_E0.6650.12
63_S192_F0.6640.12
46_N621_L0.6640.12
182_I455_E0.6640.12
286_A564_H0.6640.12
342_V508_L0.6640.12
100_L333_Y0.6630.12
568_R623_K0.6630.12
285_S313_S0.6620.12
79_L84_F0.6610.12
25_D428_E0.6600.12
118_G171_V0.6600.12
348_A432_S0.6580.12
189_R202_T0.6580.12
339_E518_N0.6570.12
64_F480_F0.6560.12
461_I507_K0.6560.12
392_V438_S0.6550.12
121_A156_R0.6540.12
67_R409_I0.6530.12
294_T492_M0.6520.12
316_I326_V0.6510.12
200_I264_L0.6510.12
67_R390_N0.6500.12
120_E205_P0.6490.12
439_L606_R0.6490.12
8_E330_E0.6490.12
70_F328_E0.6470.12
80_V216_L0.6470.12
57_D117_K0.6460.12
443_L553_A0.6460.12
32_E153_D0.6450.12
45_F418_I0.6440.12
147_P322_Y0.6440.12
515_E587_T0.6430.12
34_P109_S0.6410.12
212_D216_L0.6410.12
318_M398_K0.6410.12
289_L337_I0.6400.12
105_S215_D0.6390.12
67_R121_A0.6380.12
398_K509_R0.6380.12
128_G189_R0.6370.12
76_L398_K0.6370.12
287_D520_D0.6370.12
364_L458_L0.6360.12
481_V488_A0.6360.12
322_Y363_R0.6350.12
156_R451_S0.6350.12
97_I107_G0.6350.12
91_L95_K0.6340.12
259_C266_H0.6330.12
67_R343_A0.6330.12
379_R594_E0.6320.12
572_Q612_G0.6320.12
350_H497_D0.6310.12
334_E610_E0.6310.12
200_I273_E0.6290.12
139_H328_E0.6290.12
99_L411_P0.6280.12
97_I243_L0.6280.12
140_E614_N0.6280.12
342_V470_D0.6280.12
64_F422_I0.6270.12
216_L544_E0.6270.12
164_G491_L0.6260.12
296_E299_Y0.6260.12
362_T460_F0.6260.12
579_L597_L0.6260.12
32_E516_E0.6250.12
120_E322_Y0.6250.12
140_E167_S0.6240.12
175_E499_V0.6240.12
231_E273_E0.6220.11
168_P234_P0.6220.11
141_D170_N0.6220.11
25_D149_H0.6220.11
36_V79_L0.6210.11
173_R403_D0.6200.11
483_S493_D0.6190.11
52_G166_L0.6190.11
243_L532_G0.6170.11
89_K341_D0.6160.11
332_I410_D0.6150.11
210_S224_T0.6150.11
441_E459_N0.6150.11
321_P332_I0.6140.11
61_K479_A0.6110.11
596_Q616_T0.6100.11
166_L501_A0.6070.11
249_G363_R0.6070.11
491_L596_Q0.6050.11
59_R75_S0.6050.11
26_Y62_Y0.6040.11
84_F527_I0.6020.11
351_T371_D0.6020.11
33_N227_E0.6010.11
216_L234_P0.6000.11
134_K334_E0.6000.11
23_F365_K0.6000.11
39_S285_S0.5990.11
215_D432_S0.5970.11
12_E362_T0.5970.11
372_I563_S0.5970.11
203_F472_A0.5970.11
307_K472_A0.5950.11
217_T239_F0.5950.11
332_I412_R0.5940.11
97_I505_K0.5940.11
222_F292_A0.5920.11
300_R481_V0.5920.11
151_R400_E0.5910.11
198_T557_K0.5910.11
196_K454_R0.5880.11
501_A519_P0.5880.11
216_L255_E0.5860.11
73_E85_H0.5850.11
156_R343_A0.5850.11
36_V75_S0.5840.11
8_E63_S0.5840.11
25_D558_R0.5830.11
31_K398_K0.5820.11
143_L556_G0.5820.11
11_R183_E0.5810.11
76_L479_A0.5810.11
12_E568_R0.5810.11
362_T604_V0.5810.11
593_D620_E0.5810.11
236_A240_D0.5800.11
214_A432_S0.5790.11
65_F71_G0.5790.11
53_I598_K0.5780.11
11_R503_C0.5770.11
215_D464_A0.5770.11
94_R374_L0.5770.11
9_K75_S0.5760.11
277_K578_D0.5760.11
254_Q283_L0.5750.11
421_T497_D0.5740.11
210_S413_Y0.5740.11
269_S447_P0.5740.11
11_R163_E0.5740.11
206_S279_G0.5730.11
345_V424_R0.5730.11
143_L541_F0.5710.11
96_R411_P0.5710.11
280_R431_N0.5700.11
270_L564_H0.5700.11
60_K356_A0.5690.11
161_R459_N0.5690.11
137_P310_A0.5670.11
362_T507_K0.5660.11
26_Y30_I0.5660.11
428_E607_L0.5650.11
178_Y185_V0.5640.11
290_I375_V0.5640.11
298_E302_F0.5640.11
388_G560_D0.5630.11
354_V447_P0.5630.11
148_H155_Y0.5630.11
545_I614_N0.5620.11
236_A310_A0.5620.11
504_N547_I0.5610.11
10_Y182_I0.5610.11
25_D165_S0.5610.11
65_F363_R0.5600.11
212_D221_D0.5590.11
496_L510_D0.5580.11
35_M360_I0.5580.11
227_E362_T0.5570.11
461_I614_N0.5570.11
366_E459_N0.5570.11
78_R289_L0.5560.11
95_K310_A0.5560.11
83_Y98_L0.5550.10
58_G64_F0.5540.10
556_G572_Q0.5530.10
34_P108_K0.5530.10
61_K178_Y0.5520.10
25_D63_S0.5520.10
425_K615_S0.5520.10
40_A156_R0.5510.10
287_D465_R0.5500.10
346_H617_S0.5490.10
355_A464_A0.5490.10
410_D432_S0.5470.10
345_V443_L0.5460.10
119_L199_G0.5460.10
53_I499_V0.5460.10
109_S333_Y0.5460.10
274_G410_D0.5460.10
451_S508_L0.5440.10
338_A478_K0.5430.10
425_K430_I0.5430.10
147_P520_D0.5430.10
15_Q382_D0.5420.10
465_R484_Y0.5420.10
12_E153_D0.5420.10
290_I310_A0.5420.10
41_H47_M0.5410.10
47_M411_P0.5410.10
106_G182_I0.5410.10
449_I453_D0.5400.10
222_F283_L0.5390.10
239_F267_L0.5370.10
26_Y140_E0.5370.10
277_K625_V0.5360.10
128_G147_P0.5360.10
89_K360_I0.5360.10
359_S410_D0.5350.10
216_L309_E0.5350.10
303_I554_R0.5350.10
151_R277_K0.5340.10
109_S329_E0.5340.10
504_N509_R0.5340.10
258_K302_F0.5330.10
109_S151_R0.5320.10
59_R156_R0.5320.10
78_R161_R0.5320.10
523_L624_Y0.5320.10
485_E607_L0.5320.10
102_G329_E0.5310.10
233_D538_K0.5300.10
10_Y251_M0.5300.10
134_K230_S0.5300.10
8_E593_D0.5290.10
218_G273_E0.5280.10
428_E616_T0.5270.10
330_E344_D0.5270.10
287_D445_Q0.5270.10
333_Y410_D0.5250.10
351_T599_K0.5250.10
402_N489_K0.5240.10
273_E432_S0.5240.10
104_V299_Y0.5240.10
263_F294_T0.5240.10
109_S252_E0.5230.10
56_I384_E0.5230.10
620_E626_G0.5220.10
155_Y471_I0.5220.10
206_S270_L0.5220.10
16_R63_S0.5220.10
179_G353_K0.5220.10
293_H576_F0.5220.10
105_S447_P0.5220.10
70_F304_S0.5210.10
228_Y595_Q0.5190.10
334_E338_A0.5180.10
330_E362_T0.5180.10
239_F419_S0.5170.10
30_I508_L0.5170.10
512_L611_H0.5170.10
61_K327_S0.5150.10
311_L564_H0.5140.10
35_M334_E0.5140.10
397_M443_L0.5140.10
262_K276_F0.5140.10
14_E373_D0.5140.10
338_A610_E0.5140.10
227_E461_I0.5130.10
574_K626_G0.5130.10
179_G453_D0.5130.10
365_K401_Y0.5130.10
168_P293_H0.5120.10
168_P218_G0.5110.10
36_V232_S0.5110.10
212_D381_Y0.5110.10
238_R294_T0.5100.10
320_V509_R0.5100.10
188_E562_N0.5100.10
547_I579_L0.5100.10
189_R257_L0.5090.10
116_K252_E0.5090.10
237_Y267_L0.5080.10
93_V99_L0.5080.10
119_L197_R0.5070.10
99_L128_G0.5070.10
36_V46_N0.5070.10
291_V611_H0.5070.10
254_Q285_S0.5070.10
97_I567_L0.5060.10
135_G184_D0.5060.10
240_D311_L0.5060.10
164_G258_K0.5050.10
507_K531_I0.5050.10
153_D157_E0.5040.10
255_E264_L0.5040.10
177_E185_V0.5040.10
63_S558_R0.5030.10
350_H394_V0.5030.10
117_K615_S0.5030.10
510_D517_M0.5020.10
384_E389_Y0.5020.10
128_G257_L0.5010.10
33_N394_V0.5010.10
538_K559_F0.5010.10
97_I224_T0.5010.10
103_P332_I0.5010.10
217_T397_M0.5010.10
267_L625_V0.5000.10
218_G234_P0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1g8pA 1 0.4612 99.5 0.931 Contact Map
2r44A 1 0.4754 99.3 0.938 Contact Map
4r7yA 3 0.5182 99.2 0.94 Contact Map
1g41A 3 0.4548 99.2 0.94 Contact Map
3pxiA 3 0.4532 99.2 0.94 Contact Map
3k1jA 4 0.6926 99.2 0.941 Contact Map
1ofhA 3 0.4311 99.1 0.942 Contact Map
3ja82 1 0.5483 99.1 0.942 Contact Map
3sylA 2 0.4279 99.1 0.944 Contact Map
1um8A 1 0.3914 99 0.944 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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