LPLD - BACSU - GREMLIN Contacts

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LPLD - Alpha-galacturonidase

UniProt:	P39130	Sequences: MFHISTLDQIKIAYIGGGSQGWARSLMSDLSIDERMSGTVALYDLDFEAAQKNEVIGNHSGNGRWRYEAVSTLKKALSAADIVIISILPGSLDDMEVDVHLPERCGIYQSVGDTVGPGGIIRGLRAVPIFAEIARAIRDYAPESWVINYTNPMSVCTRVLYKVFPGIKAIGCCHEVFGTQKLLAEMVTERLGIEVPRREDIRVNVLGINHFTWITKASYRHIDLLPIFREFSAHYGESGYELEGECWRDSVFCSAHRVAFDLFETYGAIPAAGDRHLAEFLPGPYLKQPEVWKFHLTPISFRKQDRAEKRQETERLIVQQRGVAEKASGEEGVNIIAALLGLGELVTNVNMPNQGQVLNLPIQAIVETNAFITRNRVQPILSGALPKGVEMLAARHISNQEAVADAGLTKDTGLAFQAFLNDPLVQIDRSDAEQLFNDMLQCIMQS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	446 (410)
Sequences:	1740 (1005)
Seq/√Len:	49.6

ECOLI - AGAL CHBF GLVG
BACSU - LPLD GLVA AGAL LICH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
74_K	139_D	5.612	1.00
200_D	220_R	4.279	1.00
77_L	141_A	4.002	1.00
82_I	340_L	3.950	1.00
73_L	136_A	3.824	1.00
104_R	438_D	3.402	1.00
137_I	146_V	3.330	1.00
54_E	69_A	3.272	1.00
373_T	378_Q	3.170	1.00
412_T	437_N	3.119	1.00
72_T	75_K	3.092	1.00
216_K	223_D	3.081	1.00
416_F	436_F	3.049	1.00
137_I	167_I	2.993	1.00
74_K	136_A	2.987	1.00
338_A	345_L	2.980	1.00
107_I	435_L	2.856	1.00
349_V	372_I	2.807	1.00
39_T	68_E	2.735	1.00
39_T	66_R	2.731	1.00
222_I	227_I	2.548	1.00
358_L	384_A	2.540	1.00
415_A	436_F	2.535	1.00
54_E	58_N	2.518	1.00
11_K	41_A	2.452	1.00
356_Q	366_V	2.400	1.00
385_L	393_A	2.392	1.00
138_R	165_P	2.366	1.00
170_I	377_V	2.357	1.00
41_A	68_E	2.339	1.00
409_T	414_L	2.302	1.00
135_R	138_R	2.301	1.00
194_E	200_D	2.297	1.00
120_I	403_V	2.255	1.00
349_V	370_A	2.228	1.00
89_P	129_I	2.215	1.00
51_Q	55_V	2.208	1.00
137_I	141_A	2.123	1.00
285_Y	293_K	2.099	1.00
134_A	160_L	2.098	1.00
132_E	135_R	2.091	1.00
219_Y	224_L	2.063	1.00
360_L	393_A	2.056	1.00
107_I	117_P	2.034	1.00
162_K	405_D	2.032	1.00
138_R	166_G	2.006	1.00
127_V	159_V	1.967	0.99
354_Q	362_I	1.966	0.99
194_E	199_E	1.962	0.99
105_C	434_Q	1.961	0.99
105_C	438_D	1.943	0.99
359_N	390_E	1.911	0.99
51_Q	54_E	1.890	0.99
224_L	227_I	1.882	0.99
355_G	362_I	1.845	0.99
74_K	140_Y	1.823	0.99
161_Y	352_P	1.807	0.99
34_E	337_A	1.805	0.99
27_M	40_V	1.791	0.99
131_A	159_V	1.786	0.99
41_A	70_V	1.775	0.99
127_V	155_V	1.764	0.99
145_W	168_K	1.747	0.99
405_D	409_T	1.737	0.99
75_K	78_S	1.727	0.99
339_L	342_L	1.726	0.99
405_D	414_L	1.715	0.99
11_K	39_T	1.697	0.98
97_V	442_C	1.679	0.98
411_D	414_L	1.678	0.98
295_H	298_P	1.673	0.98
82_I	339_L	1.665	0.98
297_T	317_I	1.643	0.98
126_A	129_I	1.632	0.98
371_F	380_I	1.626	0.98
337_A	341_G	1.615	0.98
344_E	373_T	1.607	0.98
55_V	58_N	1.592	0.98
227_I	231_F	1.575	0.97
204_N	216_K	1.574	0.97
108_Y	277_L	1.547	0.97
68_E	75_K	1.543	0.97
414_L	417_Q	1.527	0.97
244_G	247_W	1.521	0.97
96_E	288_Q	1.512	0.97
81_D	143_E	1.504	0.97
191_L	228_F	1.499	0.96
130_F	160_L	1.495	0.96
120_I	399_N	1.494	0.96
47_F	51_Q	1.476	0.96
160_L	169_A	1.475	0.96
358_L	383_G	1.472	0.96
256_H	260_F	1.466	0.96
93_D	292_W	1.453	0.96
230_E	234_H	1.452	0.96
143_E	168_K	1.446	0.96
115_V	396_H	1.446	0.96
346_V	371_F	1.437	0.96
213_W	267_G	1.428	0.95
13_A	80_A	1.425	0.95
18_G	44_D	1.421	0.95
359_N	383_G	1.417	0.95
105_C	435_L	1.412	0.95
373_T	376_R	1.405	0.95
134_A	137_I	1.396	0.95
35_R	336_I	1.394	0.95
298_P	302_R	1.393	0.95
406_A	415_A	1.392	0.95
127_V	407_G	1.374	0.94
407_G	410_K	1.372	0.94
300_S	303_K	1.369	0.94
390_E	394_A	1.366	0.94
70_V	76_A	1.343	0.94
101_L	442_C	1.338	0.93
96_E	289_P	1.333	0.93
131_A	408_L	1.331	0.93
93_D	96_E	1.326	0.93
117_P	425_V	1.322	0.93
293_K	297_T	1.321	0.93
358_L	362_I	1.315	0.93
13_A	41_A	1.306	0.93
20_Q	299_I	1.293	0.92
316_L	319_Q	1.285	0.92
347_T	372_I	1.283	0.92
373_T	377_V	1.277	0.92
34_E	343_G	1.269	0.91
46_D	91_S	1.263	0.91
301_F	317_I	1.261	0.91
107_I	431_D	1.256	0.91
265_T	433_E	1.236	0.90
193_I	219_Y	1.230	0.90
247_W	250_S	1.229	0.90
85_I	130_F	1.224	0.90
435_L	439_M	1.223	0.90
296_L	300_S	1.223	0.90
13_A	77_L	1.221	0.90
419_F	439_M	1.221	0.90
200_D	219_Y	1.220	0.90
79_A	143_E	1.205	0.89
38_G	66_R	1.198	0.89
78_S	140_Y	1.196	0.89
219_Y	222_I	1.193	0.89
12_I	35_R	1.193	0.89
202_R	218_S	1.187	0.88
96_E	100_H	1.182	0.88
441_Q	444_M	1.175	0.88
83_V	137_I	1.168	0.88
128_P	407_G	1.166	0.88
301_F	304_Q	1.165	0.87
359_N	394_A	1.164	0.87
229_R	263_F	1.162	0.87
419_F	432_A	1.161	0.87
375_N	378_Q	1.154	0.87
206_L	215_T	1.154	0.87
51_Q	69_A	1.146	0.87
206_L	385_L	1.146	0.87
346_V	380_I	1.144	0.87
289_P	292_W	1.143	0.86
294_F	298_P	1.142	0.86
211_F	396_H	1.138	0.86
83_V	144_S	1.130	0.86
412_T	436_F	1.129	0.86
98_D	125_R	1.124	0.86
77_L	140_Y	1.121	0.85
302_R	305_D	1.112	0.85
358_L	381_L	1.111	0.85
130_F	156_C	1.109	0.85
10_I	340_L	1.107	0.85
256_H	259_A	1.107	0.85
97_V	443_I	1.103	0.84
387_K	398_S	1.096	0.84
399_N	419_F	1.093	0.84
88_L	95_M	1.093	0.84
256_H	261_D	1.086	0.84
276_H	280_F	1.079	0.83
102_P	105_C	1.072	0.83
356_Q	368_T	1.072	0.83
43_Y	76_A	1.068	0.82
15_I	146_V	1.059	0.82
420_L	429_R	1.058	0.82
388_G	417_Q	1.045	0.81
223_D	226_P	1.044	0.81
416_F	432_A	1.040	0.81
351_M	370_A	1.040	0.81
135_R	139_D	1.038	0.81
278_A	282_P	1.030	0.80
87_I	133_I	1.029	0.80
416_F	433_E	1.025	0.80
107_I	426_Q	1.023	0.80
57_G	67_Y	1.022	0.80
342_L	374_R	1.020	0.79
301_F	305_D	1.018	0.79
227_I	230_E	1.013	0.79
102_P	439_M	1.009	0.79
158_R	401_E	1.008	0.79
357_V	366_V	1.007	0.79
121_I	440_L	1.004	0.78
154_S	400_Q	1.004	0.78
211_F	392_L	1.003	0.78
415_A	440_L	0.990	0.77
120_I	419_F	0.990	0.77
138_R	167_I	0.989	0.77
95_M	99_V	0.988	0.77
277_L	280_F	0.985	0.77
216_K	225_L	0.982	0.77
123_G	365_I	0.975	0.76
47_F	71_S	0.973	0.76
205_V	214_I	0.968	0.76
136_A	140_Y	0.966	0.76
371_F	378_Q	0.966	0.76
278_A	281_L	0.958	0.75
50_A	69_A	0.956	0.75
180_Q	203_V	0.953	0.75
156_C	159_V	0.952	0.75
134_A	166_G	0.940	0.74
275_R	279_E	0.939	0.74
243_E	246_C	0.938	0.73
364_A	397_I	0.936	0.73
426_Q	431_D	0.936	0.73
202_R	346_V	0.935	0.73
346_V	369_N	0.934	0.73
173_C	210_H	0.934	0.73
178_G	182_L	0.933	0.73
251_V	254_S	0.932	0.73
87_I	153_M	0.932	0.73
262_L	266_Y	0.928	0.73
164_F	167_I	0.928	0.73
135_R	164_F	0.926	0.72
15_I	133_I	0.919	0.72
13_A	43_Y	0.918	0.72
82_I	336_I	0.911	0.71
412_T	433_E	0.911	0.71
96_E	292_W	0.910	0.71
359_N	366_V	0.908	0.71
295_H	302_R	0.903	0.71
119_G	125_R	0.901	0.70
93_D	97_V	0.900	0.70
109_Q	118_G	0.897	0.70
420_L	432_A	0.897	0.70
205_V	212_T	0.896	0.70
419_F	435_L	0.894	0.70
298_P	301_F	0.893	0.70
425_V	432_A	0.893	0.70
105_C	280_F	0.893	0.70
412_T	416_F	0.892	0.70
158_R	162_K	0.892	0.70
23_A	86_S	0.891	0.70
299_I	303_K	0.890	0.69
412_T	440_L	0.889	0.69
231_F	235_Y	0.887	0.69
334_N	345_L	0.885	0.69
80_A	141_A	0.885	0.69
242_L	248_R	0.884	0.69
351_M	372_I	0.883	0.69
249_D	253_C	0.883	0.69
114_T	119_G	0.880	0.69
294_F	301_F	0.880	0.69
77_L	83_V	0.879	0.68
247_W	251_V	0.878	0.68
315_R	321_R	0.872	0.68
194_E	219_Y	0.871	0.68
117_P	419_F	0.870	0.68
396_H	422_D	0.862	0.67
162_K	401_E	0.857	0.66
288_Q	291_V	0.856	0.66
294_F	297_T	0.856	0.66
260_F	263_F	0.853	0.66
115_V	422_D	0.852	0.66
58_N	75_K	0.847	0.66
439_M	442_C	0.844	0.65
146_V	160_L	0.843	0.65
100_H	289_P	0.837	0.65
248_R	251_V	0.835	0.64
364_A	401_E	0.835	0.64
391_M	398_S	0.834	0.64
372_I	377_V	0.832	0.64
149_Y	332_G	0.831	0.64
434_Q	437_N	0.829	0.64
26_L	86_S	0.826	0.64
337_A	343_G	0.826	0.64
88_L	99_V	0.824	0.63
58_N	66_R	0.821	0.63
10_I	38_G	0.818	0.63
89_P	126_A	0.816	0.63
297_T	301_F	0.816	0.63
14_Y	84_I	0.815	0.63
293_K	296_L	0.814	0.62
177_F	335_I	0.811	0.62
204_N	382_S	0.810	0.62
175_E	260_F	0.809	0.62
123_G	127_V	0.809	0.62
295_H	301_F	0.808	0.62
29_D	174_H	0.808	0.62
370_A	379_P	0.806	0.62
244_G	250_S	0.802	0.61
132_E	136_A	0.794	0.61
164_F	408_L	0.792	0.60
170_I	339_L	0.789	0.60
294_F	302_R	0.787	0.60
402_A	417_Q	0.787	0.60
102_P	435_L	0.786	0.60
193_I	200_D	0.781	0.59
145_W	339_L	0.780	0.59
226_P	230_E	0.773	0.58
101_L	438_D	0.768	0.58
11_K	80_A	0.768	0.58
357_V	383_G	0.766	0.58
153_M	176_V	0.765	0.58
17_G	432_A	0.765	0.58
158_R	397_I	0.764	0.58
114_T	155_V	0.760	0.57
398_S	401_E	0.751	0.56
147_I	336_I	0.749	0.56
129_I	132_E	0.749	0.56
41_A	193_I	0.749	0.56
135_R	165_P	0.748	0.56
117_P	435_L	0.744	0.56
98_D	119_G	0.742	0.55
243_E	248_R	0.741	0.55
121_I	141_A	0.740	0.55
315_R	318_V	0.738	0.55
180_Q	214_I	0.737	0.55
40_V	437_N	0.737	0.55
48_E	355_G	0.733	0.54
120_I	415_A	0.732	0.54
280_F	283_G	0.731	0.54
179_T	212_T	0.731	0.54
115_V	211_F	0.730	0.54
121_I	439_M	0.729	0.54
73_L	77_L	0.729	0.54
47_F	230_E	0.728	0.54
157_T	171_G	0.727	0.54
51_Q	378_Q	0.723	0.53
277_L	281_L	0.722	0.53
348_N	369_N	0.722	0.53
149_Y	154_S	0.721	0.53
48_E	51_Q	0.721	0.53
206_L	382_S	0.720	0.53
134_A	165_P	0.720	0.53
40_V	65_W	0.720	0.53
186_M	228_F	0.719	0.53
276_H	279_E	0.718	0.53
102_P	118_G	0.716	0.53
17_G	54_E	0.716	0.53
68_E	139_D	0.715	0.53
338_A	347_T	0.714	0.53
395_R	421_N	0.713	0.52
121_I	443_I	0.711	0.52
154_S	211_F	0.710	0.52
24_R	113_D	0.710	0.52
359_N	384_A	0.709	0.52
244_G	248_R	0.708	0.52
109_Q	400_Q	0.707	0.52
19_S	22_W	0.706	0.52
211_F	422_D	0.705	0.52
73_L	132_E	0.705	0.52
48_E	362_I	0.703	0.51
97_V	101_L	0.703	0.51
106_G	282_P	0.701	0.51
131_A	164_F	0.699	0.51
95_M	443_I	0.696	0.51
199_E	222_I	0.695	0.51
83_V	141_A	0.693	0.50
30_L	380_I	0.690	0.50
246_C	251_V	0.688	0.50
173_C	209_N	0.687	0.50
134_A	167_I	0.687	0.50
53_N	69_A	0.685	0.50
113_D	122_R	0.682	0.49
218_S	223_D	0.682	0.49
146_V	169_A	0.681	0.49
58_N	143_E	0.679	0.49
416_F	419_F	0.677	0.49
42_L	57_G	0.676	0.49
154_S	396_H	0.675	0.49
29_D	330_E	0.675	0.49
261_D	422_D	0.675	0.49
388_G	393_A	0.673	0.48
434_Q	438_D	0.673	0.48
397_I	400_Q	0.672	0.48
80_A	83_V	0.672	0.48
315_R	323_V	0.671	0.48
436_F	440_L	0.670	0.48
294_F	305_D	0.669	0.48
151_N	209_N	0.667	0.48
361_P	364_A	0.667	0.48
109_Q	112_G	0.666	0.48
302_R	306_R	0.666	0.48
275_R	278_A	0.666	0.48
53_N	57_G	0.664	0.47
403_V	419_F	0.664	0.47
88_L	400_Q	0.664	0.47
303_K	306_R	0.662	0.47
32_I	64_R	0.662	0.47
70_V	75_K	0.659	0.47
60_S	312_E	0.658	0.47
201_I	219_Y	0.657	0.47
194_E	220_R	0.657	0.47
77_L	136_A	0.657	0.47
205_V	348_N	0.656	0.47
199_E	220_R	0.656	0.47
161_Y	169_A	0.655	0.47
246_C	250_S	0.654	0.46
440_L	444_M	0.652	0.46
126_A	407_G	0.652	0.46
66_R	220_R	0.650	0.46
314_E	318_V	0.649	0.46
295_H	299_I	0.648	0.46
102_P	121_I	0.647	0.46
435_L	438_D	0.646	0.46
243_E	247_W	0.643	0.45
87_I	323_V	0.643	0.45
75_K	441_Q	0.642	0.45
261_D	276_H	0.641	0.45
84_I	168_K	0.641	0.45
313_T	316_L	0.640	0.45
88_L	122_R	0.640	0.45
362_I	384_A	0.639	0.45
38_G	64_R	0.638	0.45
149_Y	331_E	0.637	0.45
183_L	217_A	0.637	0.45
15_I	77_L	0.637	0.45
242_L	246_C	0.637	0.45
99_V	113_D	0.637	0.45
94_D	443_I	0.637	0.45
402_A	418_A	0.636	0.45
147_I	170_I	0.634	0.44
12_I	336_I	0.633	0.44
134_A	164_F	0.632	0.44
257_R	260_F	0.630	0.44
394_A	398_S	0.630	0.44
359_N	385_L	0.630	0.44
32_I	338_A	0.630	0.44
295_H	304_Q	0.629	0.44
117_P	161_Y	0.628	0.44
55_V	69_A	0.628	0.44
387_K	394_A	0.624	0.43
22_W	339_L	0.624	0.43
99_V	109_Q	0.623	0.43
203_V	214_I	0.622	0.43
399_N	403_V	0.622	0.43
213_W	417_Q	0.620	0.43
259_A	262_L	0.619	0.43
19_S	25_S	0.617	0.43
430_S	434_Q	0.614	0.42
159_V	407_G	0.614	0.42
225_L	229_R	0.614	0.42
215_T	384_A	0.612	0.42
180_Q	198_R	0.612	0.42
169_A	365_I	0.612	0.42
51_Q	252_F	0.611	0.42
339_L	343_G	0.611	0.42
123_G	159_V	0.609	0.42
50_A	71_S	0.608	0.42
25_S	329_G	0.607	0.42
13_A	78_S	0.606	0.42
126_A	156_C	0.604	0.41
262_L	318_V	0.604	0.41
104_R	280_F	0.603	0.41
115_V	399_N	0.601	0.41
78_S	135_R	0.600	0.41
16_G	19_S	0.600	0.41
369_N	386_P	0.600	0.41
302_R	307_A	0.597	0.41
194_E	198_R	0.596	0.41
181_K	185_E	0.595	0.40
15_I	45_L	0.593	0.40
12_I	30_L	0.592	0.40
47_F	139_D	0.591	0.40
114_T	125_R	0.591	0.40
419_F	425_V	0.591	0.40
356_Q	363_Q	0.590	0.40
184_A	193_I	0.590	0.40
193_I	220_R	0.589	0.40
368_T	382_S	0.588	0.40
164_F	169_A	0.588	0.40
58_N	93_D	0.586	0.40
151_N	210_H	0.586	0.40
259_A	263_F	0.586	0.40
392_L	402_A	0.585	0.40
175_E	261_D	0.585	0.40
43_Y	70_V	0.583	0.39
15_I	73_L	0.583	0.39
109_Q	113_D	0.582	0.39
270_P	274_D	0.581	0.39
88_L	109_Q	0.581	0.39
410_K	438_D	0.580	0.39
131_A	135_R	0.579	0.39
133_I	146_V	0.579	0.39
396_H	400_Q	0.578	0.39
40_V	222_I	0.578	0.39
393_A	417_Q	0.577	0.39
23_A	26_L	0.577	0.39
344_E	371_F	0.575	0.39
312_E	316_L	0.574	0.38
61_G	335_I	0.574	0.38
202_R	216_K	0.574	0.38
363_Q	407_G	0.574	0.38
43_Y	77_L	0.573	0.38
78_S	354_Q	0.572	0.38
344_E	374_R	0.571	0.38
31_S	36_M	0.571	0.38
175_E	179_T	0.570	0.38
61_G	67_Y	0.569	0.38
371_F	381_L	0.568	0.38
175_E	212_T	0.568	0.38
230_E	339_L	0.567	0.38
140_Y	200_D	0.567	0.38
109_Q	153_M	0.565	0.38
175_E	331_E	0.565	0.38
204_N	215_T	0.563	0.37
95_M	114_T	0.563	0.37
85_I	169_A	0.563	0.37
151_N	173_C	0.563	0.37
263_F	270_P	0.562	0.37
99_V	400_Q	0.562	0.37
22_W	92_L	0.560	0.37
134_A	350_N	0.559	0.37
219_Y	227_I	0.559	0.37
301_F	306_R	0.558	0.37
336_I	383_G	0.558	0.37
99_V	112_G	0.558	0.37
85_I	150_T	0.558	0.37
121_I	394_A	0.557	0.37
319_Q	441_Q	0.556	0.37
85_I	146_V	0.556	0.37
122_R	126_A	0.555	0.37
242_L	245_E	0.555	0.37
337_A	370_A	0.555	0.37
161_Y	350_N	0.555	0.37
12_I	106_G	0.553	0.36
88_L	103_E	0.553	0.36
184_A	363_Q	0.553	0.36
54_E	67_Y	0.551	0.36
115_V	155_V	0.551	0.36
52_K	410_K	0.549	0.36
202_R	384_A	0.549	0.36
402_A	421_N	0.548	0.36
354_Q	381_L	0.546	0.36
386_P	389_V	0.546	0.36
276_H	330_E	0.545	0.36
101_L	435_L	0.542	0.35
143_E	194_E	0.541	0.35
127_V	403_V	0.540	0.35
98_D	116_G	0.539	0.35
132_E	139_D	0.539	0.35
14_Y	91_S	0.537	0.35
155_V	404_A	0.537	0.35
361_P	401_E	0.537	0.35
11_K	79_A	0.535	0.35
101_L	105_C	0.535	0.35
145_W	170_I	0.534	0.35
184_A	213_W	0.533	0.35
161_Y	363_Q	0.532	0.34
135_R	166_G	0.532	0.34
390_E	401_E	0.530	0.34
413_G	417_Q	0.530	0.34
20_Q	92_L	0.528	0.34
171_G	423_P	0.528	0.34
97_V	104_R	0.528	0.34
51_Q	132_E	0.528	0.34
11_K	38_G	0.527	0.34
265_T	323_V	0.527	0.34
57_G	86_S	0.527	0.34
176_V	348_N	0.527	0.34
368_T	379_P	0.525	0.34
362_I	441_Q	0.525	0.34
392_L	396_H	0.525	0.34
56_I	415_A	0.525	0.34
363_Q	381_L	0.524	0.34
170_I	372_I	0.524	0.34
130_F	134_A	0.524	0.34
231_F	234_H	0.522	0.34
213_W	393_A	0.521	0.33
363_Q	437_N	0.521	0.33
297_T	302_R	0.521	0.33
141_A	167_I	0.520	0.33
30_L	40_V	0.518	0.33
22_W	331_E	0.517	0.33
289_P	293_K	0.517	0.33
124_L	407_G	0.516	0.33
88_L	443_I	0.516	0.33
332_G	336_I	0.516	0.33
77_L	133_I	0.515	0.33
115_V	365_I	0.514	0.33
226_P	256_H	0.512	0.33
215_T	386_P	0.512	0.33
85_I	137_I	0.511	0.33
363_Q	401_E	0.511	0.33
77_L	115_V	0.511	0.33
15_I	43_Y	0.511	0.33
206_L	386_P	0.510	0.32
307_A	320_Q	0.509	0.32
414_L	420_L	0.508	0.32
191_L	227_I	0.508	0.32
156_C	407_G	0.508	0.32
22_W	86_S	0.508	0.32
321_R	329_G	0.508	0.32
289_P	405_D	0.507	0.32
56_I	204_N	0.507	0.32
399_N	422_D	0.507	0.32
112_G	400_Q	0.507	0.32
58_N	68_E	0.506	0.32
235_Y	242_L	0.506	0.32
120_I	123_G	0.506	0.32
350_N	365_I	0.505	0.32
89_P	133_I	0.503	0.32
81_D	145_W	0.503	0.32
242_L	247_W	0.502	0.32
24_R	56_I	0.502	0.32
44_D	112_G	0.502	0.32
50_A	53_N	0.501	0.32
298_P	305_D	0.501	0.32
13_A	68_E	0.501	0.32
116_G	125_R	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1obbA	2	0.9305	100	0.372	Contact Map
3fefA	3	0.9619	100	0.393	Contact Map
1s6yA	1	0.8901	100	0.406	Contact Map
1up7A	3	0.9148	100	0.407	Contact Map
1u8xX	1	0.9193	100	0.407	Contact Map
3u95A	2	0.9372	100	0.429	Contact Map
1pzgA	4	0.7108	100	0.711	Contact Map
4rorA	4	0.6996	100	0.72	Contact Map
3p7mA	4	0.6996	100	0.723	Contact Map
4plzA	4	0.6525	100	0.724	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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