GREMLIN Database
GLGB - 1,4-alpha-glucan branching enzyme GlgB
UniProt: P39118 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 627 (537)
Sequences: 9014 (5983)
Seq/√Len: 258.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
178_P232_Q4.2211.00
170_K224_K4.1501.00
228_E231_Q3.9341.00
170_K221_D3.8911.00
497_D579_Y3.7891.00
182_K496_Q3.7021.00
453_V533_F3.2811.00
67_M78_L3.2111.00
181_K232_Q3.2041.00
223_M300_F3.1701.00
188_I229_C3.0301.00
222_L226_V2.9591.00
287_H335_K2.9131.00
467_A491_A2.9081.00
500_R504_K2.7951.00
448_L495_T2.7561.00
218_P221_D2.7131.00
341_R372_H2.7021.00
228_E232_Q2.6271.00
159_K175_T2.6171.00
38_G79_F2.5791.00
479_D482_L2.4811.00
525_N528_Q2.4481.00
296_Y301_Y2.4091.00
134_W302_H2.3381.00
298_A347_V2.2881.00
224_K228_E2.2141.00
417_F464_S2.1921.00
190_L193_V2.1751.00
190_L225_F2.1731.00
222_L303_I2.1721.00
288_S292_S2.1671.00
177_I232_Q2.1631.00
453_V546_I2.1101.00
242_P293_N2.0981.00
153_L158_W2.0741.00
50_E66_V2.0711.00
173_S224_K2.0671.00
172_L225_F2.0641.00
220_H223_M2.0291.00
149_F499_L2.0001.00
147_P509_Y1.9481.00
260_L263_Y1.9411.00
493_V496_Q1.9161.00
148_V187_H1.9151.00
39_Y83_I1.9091.00
258_E264_K1.9081.00
520_W523_V1.9071.00
230_H304_D1.8941.00
50_E94_V1.8891.00
505_S542_E1.8881.00
52_R92_E1.8791.00
170_K173_S1.8571.00
193_V222_L1.8541.00
340_M347_V1.8411.00
261_Y264_K1.8401.00
92_E102_L1.8381.00
84_G87_E1.8301.00
174_Q228_E1.8241.00
452_T499_L1.8241.00
182_K492_S1.8151.00
299_E343_A1.8101.00
221_D224_K1.8071.00
54_A102_L1.8061.00
258_E263_Y1.8051.00
222_L225_F1.8031.00
339_T342_E1.7981.00
28_S39_Y1.7981.00
225_F229_C1.7941.00
51_V93_I1.7901.00
137_K302_H1.7621.00
534_I543_A1.7521.00
476_E479_D1.7391.00
497_D500_R1.7361.00
505_S544_L1.7211.00
477_Q482_L1.7181.00
473_K476_E1.7091.00
227_D231_Q1.7061.00
30_Y39_Y1.7021.00
52_R94_V1.7001.00
210_Y293_N1.7001.00
155_L172_L1.6911.00
436_D439_Q1.6871.00
153_L180_I1.6781.00
258_E262_E1.6751.00
148_V348_M1.6731.00
43_V51_V1.6651.00
501_F571_V1.6431.00
43_V93_I1.6371.00
173_S228_E1.6331.00
477_Q481_F1.6281.00
534_I545_V1.6271.00
519_E536_Y1.6241.00
570_E573_N1.6241.00
529_S551_T1.6171.00
515_A523_V1.6151.00
247_K270_E1.6121.00
180_I234_I1.6111.00
42_C77_T1.5991.00
521_I545_V1.5971.00
83_I87_E1.5951.00
260_L264_K1.5921.00
88_R112_E1.5891.00
65_H78_L1.5811.00
332_F336_L1.5771.00
112_E116_N1.5681.00
441_F488_H1.5651.00
295_L339_T1.5611.00
258_E261_Y1.5421.00
296_Y300_F1.5421.00
127_Y227_D1.5311.00
150_I414_V1.5251.00
466_F478_L1.5191.00
362_G366_E1.5151.00
41_F91_Y1.5131.00
111_S208_G1.5071.00
489_Q493_V1.4891.00
180_I188_I1.4871.00
492_S496_Q1.4871.00
493_V497_D1.4821.00
52_R66_V1.4761.00
30_Y85_E1.4741.00
294_A336_L1.4731.00
62_G92_E1.4721.00
31_R79_F1.4581.00
172_L190_L1.4531.00
54_A92_E1.4531.00
279_F286_V1.4521.00
163_D166_H1.4411.00
49_S96_N1.4381.00
64_E92_E1.4351.00
331_D334_K1.4341.00
405_L409_F1.4301.00
298_A340_M1.4281.00
395_R527_E1.4171.00
195_E214_S1.4161.00
212_P222_L1.4141.00
445_R494_F1.3991.00
482_L488_H1.3971.00
49_S94_V1.3961.00
359_Q362_G1.3851.00
42_C75_I1.3841.00
532_S547_I1.3771.00
494_F574_S1.3741.00
448_L460_I1.3671.00
165_R171_E1.3671.00
104_A111_S1.3581.00
187_H237_I1.3571.00
170_K174_Q1.3401.00
404_S454_H1.3301.00
295_L299_E1.3181.00
229_C234_I1.3171.00
194_Y293_N1.3171.00
521_I534_I1.3131.00
179_Y492_S1.3111.00
195_E213_T1.3051.00
210_Y292_S1.3041.00
379_W454_H1.3001.00
65_H80_I1.2991.00
52_R64_E1.2961.00
56_D87_E1.2951.00
153_L188_I1.2941.00
259_P264_K1.2931.00
337_N341_R1.2921.00
153_L172_L1.2921.00
425_G444_Y1.2901.00
95_T101_R1.2891.00
280_D283_K1.2841.00
285_E288_S1.2791.00
262_E265_E1.2751.00
156_G160_K1.2721.00
131_D302_H1.2711.00
295_L343_A1.2631.00
40_E77_T1.2631.00
177_I228_E1.2621.00
69_R72_D1.2601.00
39_Y121_T1.2591.00
87_E121_T1.2471.00
240_W294_A1.2371.00
515_A518_F1.2351.00
437_Y469_F1.2341.00
390_P393_E1.2321.00
444_Y467_A1.2321.00
259_P262_E1.2311.00
291_I339_T1.2281.00
476_E482_L1.2281.00
148_V186_T1.2271.00
494_F572_L1.2261.00
237_I350_I1.2181.00
158_W176_L1.2131.00
260_L265_E1.2111.00
485_F488_H1.2101.00
448_L498_L1.2101.00
264_K267_R1.2091.00
187_H235_G1.2061.00
298_A344_Y1.2021.00
155_L190_L1.1931.00
135_Q227_D1.1921.00
31_R36_K1.1891.00
180_I184_G1.1881.00
338_Q364_V1.1871.00
291_I336_L1.1791.00
499_L503_Q1.1791.00
168_S171_E1.1761.00
537_G541_G1.1761.00
263_Y266_E1.1761.00
134_W137_K1.1751.00
259_P265_E1.1701.00
178_P182_K1.1691.00
259_P263_Y1.1621.00
178_P181_K1.1581.00
177_I229_C1.1541.00
387_M447_L1.1511.00
533_F546_I1.1511.00
94_V100_I1.1511.00
169_Y212_P1.1511.00
449_G494_F1.1471.00
427_K431_N1.1441.00
28_S91_Y1.1411.00
496_Q500_R1.1361.00
90_K102_L1.1361.00
263_Y267_R1.1301.00
281_L290_L1.1291.00
194_Y206_G1.1271.00
107_Y261_Y1.1261.00
460_I464_S1.1241.00
180_I185_F1.1211.00
40_E79_F1.1161.00
132_Q224_K1.1151.00
127_Y130_Q1.1101.00
497_D578_T1.1091.00
441_F445_R1.1081.00
189_E375_W1.1071.00
143_L187_H1.1051.00
111_S211_S1.1021.00
22_S25_L1.1021.00
336_L349_M1.1011.00
415_L418_S1.0971.00
337_N349_M1.0941.00
229_C236_V1.0921.00
212_P297_W1.0881.00
518_F521_I1.0861.00
132_Q135_Q1.0841.00
381_N385_K1.0841.00
385_K388_E1.0801.00
31_R37_S1.0781.00
441_F444_Y1.0761.00
183_H492_S1.0751.00
92_E100_I1.0691.00
108_A119_S1.0691.00
522_D525_N1.0681.00
31_R40_E1.0651.00
437_Y440_K1.0651.00
198_Y205_Q1.0641.00
108_A111_S1.0591.00
260_L266_E1.0581.00
222_L301_Y1.0571.00
335_K338_Q1.0551.00
193_V238_L1.0531.00
222_L238_L1.0531.00
26_F75_I1.0521.00
262_E266_E1.0511.00
399_Q402_S1.0501.00
39_Y84_G1.0451.00
258_E266_E1.0411.00
445_R491_A1.0391.00
385_K400_L1.0391.00
156_G216_F1.0391.00
36_K79_F1.0381.00
518_F523_V1.0351.00
445_R490_K1.0311.00
507_I544_L1.0301.00
278_N281_L1.0301.00
28_S41_F1.0291.00
335_K339_T1.0291.00
477_Q480_W1.0271.00
383_V447_L1.0261.00
80_I83_I1.0261.00
158_W172_L1.0261.00
489_Q492_S1.0251.00
338_Q342_E1.0211.00
53_V78_L1.0211.00
291_I295_L1.0211.00
478_L482_L1.0191.00
88_R120_L1.0081.00
56_D88_R1.0051.00
261_Y265_E1.0001.00
517_S520_W0.9991.00
295_L344_Y0.9991.00
238_L303_I0.9981.00
149_F503_Q0.9961.00
340_M343_A0.9951.00
124_L223_M0.9951.00
425_G429_L0.9921.00
331_D335_K0.9921.00
174_Q178_P0.9901.00
508_L544_L0.9901.00
494_F498_L0.9891.00
551_T555_Y0.9851.00
404_S407_Y0.9851.00
501_F572_L0.9841.00
271_N278_N0.9821.00
110_Y122_Y0.9781.00
460_I495_T0.9771.00
263_Y268_D0.9761.00
95_T99_E0.9751.00
135_Q138_Q0.9731.00
153_L462_M0.9731.00
264_K268_D0.9721.00
212_P296_Y0.9721.00
158_W179_Y0.9701.00
129_W132_Q0.9671.00
142_T145_E0.9661.00
250_H255_F0.9661.00
544_L571_V0.9661.00
26_F42_C0.9601.00
251_G255_F0.9581.00
452_T460_I0.9571.00
253_Y277_A0.9551.00
25_L42_C0.9521.00
536_Y543_A0.9511.00
282_G328_Y0.9501.00
450_Y548_C0.9471.00
29_H109_I0.9471.00
25_L40_E0.9431.00
155_L169_Y0.9421.00
446_L550_F0.9411.00
417_F447_L0.9401.00
22_S107_Y0.9401.00
396_H399_Q0.9381.00
294_A306_F0.9371.00
400_L406_L0.9371.00
124_L127_Y0.9371.00
278_N313_N0.9371.00
210_Y289_F0.9361.00
462_M478_L0.9321.00
172_L229_C0.9271.00
562_V568_Y0.9261.00
44_W285_E0.9251.00
446_L548_C0.9141.00
57_F61_S0.9121.00
167_Y175_T0.9111.00
126_G220_H0.9091.00
149_F452_T0.9061.00
515_A520_W0.9051.00
384_L388_E0.9011.00
416_P447_L0.9001.00
398_H402_S0.8991.00
382_D396_H0.8991.00
208_G211_S0.8971.00
47_H258_E0.8971.00
122_Y126_G0.8971.00
510_E538_Q0.8941.00
375_W380_M0.8911.00
150_I237_I0.8901.00
252_L255_F0.8901.00
57_F60_W0.8871.00
377_M380_M0.8861.00
244_H309_D0.8861.00
54_A64_E0.8851.00
165_R174_Q0.8841.00
389_T393_E0.8841.00
71_N77_T0.8841.00
448_L491_A0.8831.00
530_I558_Y0.8761.00
448_L464_S0.8761.00
309_D420_D0.8721.00
443_Q446_L0.8711.00
429_L448_L0.8681.00
46_P74_G0.8671.00
55_G65_H0.8661.00
330_V334_K0.8631.00
397_C400_L0.8621.00
449_G574_S0.8611.00
83_I121_T0.8581.00
55_G87_E0.8581.00
399_Q406_L0.8561.00
410_S414_V0.8550.99
30_Y36_K0.8520.99
109_I124_L0.8510.99
261_Y266_E0.8500.99
383_V450_Y0.8440.99
209_Y289_F0.8420.99
361_T364_V0.8390.99
174_Q224_K0.8390.99
488_H491_A0.8390.99
186_T234_I0.8390.99
68_H77_T0.8380.99
284_P288_S0.8370.99
194_Y303_I0.8370.99
309_D352_E0.8360.99
209_Y279_F0.8350.99
537_G540_H0.8350.99
411_E414_V0.8340.99
195_E211_S0.8320.99
380_M384_L0.8320.99
501_F505_S0.8290.99
109_I300_F0.8260.99
219_P301_Y0.8240.99
252_L256_D0.8230.99
250_H253_Y0.8220.99
294_A308_V0.8220.99
260_L267_R0.8210.99
114_R199_D0.8210.99
389_T400_L0.8200.99
132_Q137_K0.8180.99
137_K233_N0.8160.99
55_G60_W0.8150.99
401_I404_S0.8140.99
255_F289_F0.8110.99
287_H331_D0.8110.99
402_S405_L0.8100.99
486_P489_Q0.8090.99
466_F492_S0.8080.99
53_V80_I0.8070.99
515_A521_I0.8050.99
437_Y487_M0.8000.99
299_E344_Y0.7980.99
528_Q555_Y0.7980.99
334_K338_Q0.7960.99
395_R398_H0.7940.99
154_H191_L0.7930.99
444_Y491_A0.7920.99
107_Y292_S0.7890.99
151_Y465_E0.7880.99
294_A340_M0.7880.99
161_H167_Y0.7870.99
150_I413_F0.7870.99
31_R38_G0.7860.99
408_A413_F0.7860.99
173_S221_D0.7840.99
394_R397_C0.7830.99
425_G467_A0.7830.99
442_A445_R0.7820.99
41_F53_V0.7820.99
224_K227_D0.7820.99
400_L404_S0.7810.99
340_M349_M0.7810.99
237_I305_G0.7800.99
147_P503_Q0.7800.99
119_S123_D0.7780.99
85_E123_D0.7770.99
302_H344_Y0.7770.99
137_K141_K0.7770.99
293_N296_Y0.7760.99
449_G548_C0.7750.99
210_Y296_Y0.7740.99
401_I531_F0.7710.99
484_S489_Q0.7710.99
401_I405_L0.7700.99
259_P267_R0.7680.99
339_T343_A0.7680.99
159_K167_Y0.7660.99
472_W475_T0.7650.99
570_E576_S0.7650.99
519_E534_I0.7640.99
129_W134_W0.7620.99
537_G542_E0.7610.99
568_Y571_V0.7600.99
185_F234_I0.7590.99
245_F279_F0.7590.99
441_F490_K0.7580.99
144_Y147_P0.7540.99
307_R420_D0.7540.99
350_I459_L0.7540.99
265_E268_D0.7530.99
453_V548_C0.7520.99
131_D134_W0.7520.99
333_L336_L0.7490.99
511_H514_R0.7480.99
220_H224_K0.7440.99
449_G453_V0.7420.99
490_K493_V0.7410.99
359_Q366_E0.7410.99
206_G209_Y0.7410.99
274_W313_N0.7390.99
123_D126_G0.7370.99
167_Y171_E0.7370.99
145_E373_Y0.7360.98
24_Q300_F0.7360.98
385_K389_T0.7360.98
545_V568_Y0.7310.98
165_R168_S0.7300.98
104_A108_A0.7290.98
314_I329_A0.7290.98
530_I535_R0.7270.98
379_W383_V0.7270.98
352_E419_H0.7260.98
418_S459_L0.7250.98
449_G498_L0.7250.98
49_S98_G0.7220.98
416_P451_M0.7200.98
153_L176_L0.7190.98
132_Q136_K0.7190.98
298_A306_F0.7180.98
470_D479_D0.7150.98
58_N61_S0.7140.98
385_K390_P0.7090.98
85_E126_G0.7090.98
162_S165_R0.7050.98
66_V69_R0.7050.98
194_Y238_L0.7050.98
450_Y550_F0.7040.98
183_H499_L0.7040.98
230_H236_V0.7040.98
196_H199_D0.7020.98
169_Y225_F0.7010.98
388_E427_K0.7010.98
247_K275_G0.7000.98
226_V303_I0.7000.98
169_Y221_D0.6980.98
135_Q302_H0.6980.98
270_E275_G0.6960.98
263_Y269_R0.6950.98
270_E273_L0.6950.98
478_L481_F0.6940.98
186_T503_Q0.6870.98
155_L193_V0.6870.98
117_T120_L0.6860.98
395_R399_Q0.6840.98
387_M550_F0.6840.98
326_N332_F0.6820.98
58_N65_H0.6820.98
397_C401_I0.6820.98
284_P287_H0.6820.98
447_L450_Y0.6810.98
264_K269_R0.6810.98
170_K218_P0.6810.98
169_Y217_G0.6800.97
441_F491_A0.6790.97
130_Q227_D0.6780.97
179_Y466_F0.6780.97
481_F484_S0.6750.97
149_F185_F0.6730.97
492_S495_T0.6720.97
226_V236_V0.6700.97
137_K227_D0.6700.97
109_I296_Y0.6700.97
120_L123_D0.6690.97
173_S225_F0.6680.97
123_D127_Y0.6680.97
258_E265_E0.6670.97
438_W554_V0.6660.97
498_L572_L0.6650.97
223_M301_Y0.6640.97
338_Q365_E0.6620.97
131_D135_Q0.6610.97
311_V351_A0.6600.97
110_Y120_L0.6580.97
428_S431_N0.6580.97
116_N119_S0.6560.97
72_D77_T0.6540.97
161_H165_R0.6540.97
133_K136_K0.6520.97
165_R170_K0.6520.97
532_S545_V0.6520.97
394_R402_S0.6500.97
53_V91_Y0.6490.97
67_M91_Y0.6480.97
169_Y222_L0.6480.97
529_S550_F0.6480.97
130_Q231_Q0.6460.97
55_G58_N0.6460.97
547_I560_V0.6460.97
376_N380_M0.6460.97
491_A494_F0.6450.97
399_Q404_S0.6450.97
253_Y257_G0.6450.97
49_S95_T0.6440.97
152_E191_L0.6440.97
450_Y454_H0.6440.97
88_R118_A0.6430.96
201_S216_F0.6430.96
534_I537_G0.6420.96
469_F482_L0.6410.96
409_F414_V0.6400.96
26_F107_Y0.6390.96
387_M450_Y0.6390.96
423_V428_S0.6390.96
358_P361_T0.6390.96
326_N330_V0.6360.96
25_L29_H0.6360.96
50_E68_H0.6350.96
45_A74_G0.6340.96
295_L340_M0.6330.96
291_I335_K0.6320.96
254_M257_G0.6300.96
336_L341_R0.6300.96
82_G85_E0.6300.96
51_V91_Y0.6290.96
530_I555_Y0.6290.96
143_L146_K0.6290.96
486_P490_K0.6270.96
432_K435_G0.6270.96
517_S521_I0.6270.96
565_F568_Y0.6270.96
364_V368_G0.6260.96
352_E420_D0.6230.96
308_V349_M0.6220.96
258_E267_R0.6220.96
145_E148_V0.6210.96
184_G500_R0.6200.96
518_F522_D0.6200.96
364_V367_G0.6200.96
362_G365_E0.6190.96
196_H206_G0.6190.96
54_A90_K0.6190.96
105_D108_A0.6170.96
361_T365_E0.6170.96
386_Y550_F0.6170.96
532_S535_R0.6160.96
197_P207_T0.6160.96
29_H40_E0.6160.96
244_H352_E0.6150.95
394_R398_H0.6150.95
332_F337_N0.6150.95
188_I236_V0.6140.95
161_H171_E0.6140.95
493_V578_T0.6140.95
129_W302_H0.6130.95
497_D572_L0.6130.95
227_D302_H0.6130.95
145_E348_M0.6130.95
244_H420_D0.6110.95
555_Y558_Y0.6110.95
162_S176_L0.6100.95
500_R503_Q0.6090.95
244_H419_H0.6080.95
213_T216_F0.6080.95
496_Q499_L0.6070.95
161_H477_Q0.6060.95
245_F263_Y0.6060.95
476_E480_W0.6060.95
103_K106_P0.6060.95
169_Y193_V0.6040.95
487_M490_K0.6040.95
218_P224_K0.6040.95
252_L257_G0.6030.95
185_F465_E0.6020.95
309_D419_H0.6010.95
178_P228_E0.5990.95
373_Y513_H0.5960.95
517_S523_V0.5960.95
133_K137_K0.5960.95
45_A48_A0.5960.95
181_K233_N0.5950.95
531_F535_R0.5950.95
158_W180_I0.5940.95
338_Q341_R0.5920.94
409_F413_F0.5910.94
430_L467_A0.5900.94
151_Y183_H0.5890.94
180_I229_C0.5880.94
374_K377_M0.5880.94
205_Q276_T0.5880.94
172_L188_I0.5870.94
239_D309_D0.5860.94
22_S292_S0.5860.94
65_H69_R0.5850.94
244_H307_R0.5850.94
176_L179_Y0.5850.94
511_H538_Q0.5810.94
200_R474_D0.5810.94
38_G81_P0.5800.94
262_E267_R0.5790.94
68_H78_L0.5790.94
444_Y448_L0.5770.94
119_S122_Y0.5770.94
205_Q246_C0.5770.94
179_Y182_K0.5770.94
451_M454_H0.5760.94
250_H254_M0.5750.94
400_L403_F0.5750.94
245_F261_Y0.5740.94
251_G254_M0.5740.94
541_G544_L0.5740.94
177_I181_K0.5740.94
181_K234_I0.5730.93
468_Q478_L0.5730.93
135_Q231_Q0.5730.93
117_T124_L0.5720.93
402_S406_L0.5710.93
119_S126_G0.5700.93
467_A488_H0.5670.93
167_Y170_K0.5670.93
223_M296_Y0.5670.93
453_V501_F0.5660.93
379_W382_D0.5660.93
408_A411_E0.5650.93
143_L147_P0.5640.93
506_K510_E0.5640.93
114_R166_H0.5640.93
441_F467_A0.5630.93
398_H403_F0.5620.93
518_F535_R0.5610.93
243_G310_A0.5610.93
516_Q523_V0.5590.93
307_R352_E0.5570.92
191_L462_M0.5570.92
199_D246_C0.5570.92
56_D60_W0.5550.92
274_W310_A0.5540.92
336_L342_E0.5530.92
430_L433_M0.5530.92
201_S205_Q0.5520.92
66_V76_W0.5520.92
431_N436_D0.5510.92
241_V352_E0.5510.92
547_I558_Y0.5500.92
485_F492_S0.5500.92
397_C548_C0.5470.92
272_W313_N0.5470.92
398_H401_I0.5470.92
251_G257_G0.5460.92
196_H216_F0.5460.92
114_R214_S0.5460.92
326_N333_L0.5450.92
429_L432_K0.5450.92
54_A62_G0.5450.92
279_F289_F0.5450.92
207_T246_C0.5440.92
110_Y214_S0.5420.91
181_K503_Q0.5420.91
161_H164_G0.5420.91
399_Q405_L0.5400.91
397_C402_S0.5400.91
430_L469_F0.5400.91
136_K302_H0.5390.91
210_Y242_P0.5380.91
166_H171_E0.5370.91
340_M344_Y0.5370.91
167_Y174_Q0.5370.91
336_L340_M0.5360.91
259_P266_E0.5360.91
337_N340_M0.5350.91
289_F293_N0.5350.91
298_A343_A0.5340.91
530_I533_F0.5340.91
150_I187_H0.5340.91
329_A334_K0.5340.91
263_Y280_D0.5330.91
457_K512_D0.5330.91
545_V562_V0.5330.91
430_L434_P0.5330.91
466_F482_L0.5330.91
239_D307_R0.5320.91
385_K393_E0.5320.91
41_F80_I0.5310.91
241_V244_H0.5310.91
398_H404_S0.5310.91
120_L124_L0.5310.91
326_N331_D0.5310.91
307_R419_H0.5310.91
44_W283_K0.5300.91
495_T499_L0.5300.91
271_N274_W0.5300.91
94_V99_E0.5290.90
119_S124_L0.5290.90
116_N120_L0.5280.90
198_Y215_R0.5250.90
327_P330_V0.5240.90
433_M443_Q0.5200.90
394_R403_F0.5200.90
133_K227_D0.5190.90
235_G348_M0.5180.90
145_E538_Q0.5180.90
383_V397_C0.5170.89
204_Y419_H0.5170.89
374_K378_G0.5170.89
290_L314_I0.5160.89
273_L278_N0.5160.89
112_E120_L0.5160.89
153_L190_L0.5160.89
154_H216_F0.5150.89
533_F548_C0.5150.89
171_E174_Q0.5140.89
523_V531_F0.5140.89
435_G439_Q0.5130.89
333_L337_N0.5130.89
259_P268_D0.5130.89
522_D532_S0.5100.89
160_K166_H0.5090.89
241_V309_D0.5090.89
327_P331_D0.5070.89
408_A414_V0.5060.88
470_D476_E0.5040.88
312_A354_S0.5040.88
266_E271_N0.5040.88
380_M385_K0.5040.88
538_Q541_G0.5040.88
287_H291_I0.5030.88
272_W277_A0.5030.88
533_F537_G0.5030.88
229_C232_Q0.5030.88
360_V369_L0.5020.88
134_W227_D0.5010.88
146_K509_Y0.5010.88
441_F487_M0.5010.88
394_R400_L0.5010.88
458_K502_Y0.5010.88
265_E269_R0.5010.88
179_Y183_H0.5010.88
184_G503_Q0.5000.88
521_I532_S0.5000.88
397_C403_F0.5000.88
431_N434_P0.5000.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3k1dA 1 0.9761 100 0.226 Contact Map
1m7xA 1 0.9362 100 0.25 Contact Map
3amlA 1 0.9569 100 0.272 Contact Map
4bzyA 1 0.949 100 0.275 Contact Map
3wdhA 1 0.8931 100 0.325 Contact Map
2e8yA 1 0.8995 100 0.327 Contact Map
2wanA 1 0.9059 100 0.336 Contact Map
1bf2A 1 0.9155 100 0.339 Contact Map
1wzlA 2 0.8533 100 0.342 Contact Map
1ji1A 1 0.8724 100 0.347 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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