GREMLIN Database
YPFA - Uncharacterized protein YpfA
UniProt: P38491 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 217 (198)
Sequences: 583 (522)
Seq/√Len: 37.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
168_A186_L6.4831.00
206_R209_N4.8231.00
169_V187_E4.2281.00
111_V135_V4.0101.00
130_A200_L3.6831.00
193_A196_Q3.4861.00
105_T203_C3.0031.00
71_S86_L2.9291.00
35_I86_L2.7611.00
113_I121_I2.7571.00
71_S89_P2.6461.00
23_S38_P2.3030.99
135_V186_L2.2780.99
130_A196_Q2.2250.99
196_Q200_L2.0990.99
133_I186_L2.0320.99
8_V35_I2.0080.99
111_V125_S1.9900.99
69_F89_P1.9850.98
66_P99_R1.9630.98
170_V184_M1.9050.98
26_V36_A1.9040.98
89_P105_T1.8950.98
38_P204_I1.8380.97
110_D201_Q1.8270.97
102_Y196_Q1.8140.97
65_V96_R1.8010.97
89_P92_E1.7360.96
99_R131_G1.6670.95
58_E99_R1.6620.95
112_Q152_I1.6370.95
202_Y206_R1.6000.94
26_V83_M1.5870.94
32_E85_C1.5680.94
148_S167_E1.5310.93
192_A195_D1.4920.92
156_P169_V1.4770.91
72_R87_E1.4740.91
100_R104_R1.4670.91
134_A183_K1.4280.90
111_V153_I1.4060.89
10_L23_S1.4040.89
113_I135_V1.4010.89
24_K207_Q1.3880.89
38_P44_G1.3700.88
128_I202_Y1.3630.88
81_L140_G1.3590.88
199_L211_R1.3590.88
101_Q187_E1.3540.87
21_A47_V1.3510.87
55_V86_L1.3290.86
27_S205_R1.3250.86
112_Q122_R1.3110.86
21_A38_P1.2770.84
170_V186_L1.2730.84
144_Q147_E1.2630.83
4_I28_I1.2460.83
145_S189_S1.2430.82
56_T70_I1.2370.82
71_S87_E1.2220.81
57_V71_S1.2030.80
73_I99_R1.2020.80
114_Q120_E1.2000.80
10_L55_V1.2000.80
130_A199_L1.1920.80
23_S36_A1.1850.79
102_Y200_L1.1710.78
100_R132_G1.1700.78
53_M78_K1.1700.78
128_I171_R1.1660.78
137_L184_M1.1640.78
125_S153_I1.1470.77
148_S169_V1.1450.77
110_D122_R1.1370.76
151_L168_A1.1320.76
94_M103_V1.1200.75
39_V98_Q1.1110.75
130_A153_I1.0980.74
79_D133_I1.0860.73
104_R132_G1.0770.72
22_K211_R1.0760.72
5_G10_L1.0630.71
61_G96_R1.0630.71
204_I208_L1.0610.71
15_E19_K1.0570.71
116_G167_E1.0530.71
24_K105_T1.0520.71
101_Q130_A1.0450.70
113_I137_L1.0320.69
207_Q210_K1.0280.69
10_L57_V1.0270.69
149_L186_L1.0190.68
75_G79_D1.0080.67
105_T206_R0.9970.66
129_S132_G0.9940.66
170_V173_I0.9910.66
99_R197_Q0.9880.66
167_E190_E0.9830.65
26_V207_Q0.9830.65
150_R207_Q0.9790.65
130_A193_A0.9760.65
203_C208_L0.9730.64
5_G24_K0.9730.64
34_L83_M0.9490.62
33_L181_K0.9480.62
25_A28_I0.9450.62
25_A79_D0.9410.62
130_A204_I0.9380.62
115_P147_E0.9300.61
125_S128_I0.9290.61
27_S38_P0.9250.60
184_M207_Q0.9120.59
171_R185_T0.9080.59
136_V183_K0.9060.59
169_V189_S0.9060.59
65_V94_M0.9030.59
25_A101_Q0.8950.58
127_N169_V0.8910.58
34_L85_C0.8820.57
197_Q200_L0.8740.56
207_Q213_K0.8650.55
153_I188_Y0.8570.55
39_V211_R0.8570.55
118_E149_L0.8460.54
54_E72_R0.8460.54
113_I120_E0.8450.54
58_E66_P0.8450.54
59_F177_P0.8450.54
57_V194_G0.8440.53
102_Y118_E0.8430.53
75_G172_R0.8360.53
113_I139_D0.8350.53
23_S44_G0.8310.52
37_Y46_T0.8290.52
88_M170_V0.8280.52
69_F167_E0.8250.52
134_A185_T0.8230.52
50_H73_I0.8200.51
100_R129_S0.8160.51
19_K40_D0.8130.51
24_K36_A0.8120.51
186_L199_L0.8010.50
89_P103_V0.7960.49
73_I84_I0.7950.49
8_V202_Y0.7950.49
107_A125_S0.7940.49
55_V88_M0.7920.49
158_E188_Y0.7900.49
138_A181_K0.7820.48
69_F185_T0.7790.48
173_I184_M0.7780.48
27_S123_T0.7710.47
76_K98_Q0.7710.47
96_R201_Q0.7680.47
70_I187_E0.7660.47
101_Q198_A0.7660.47
57_V192_A0.7640.46
4_I12_Y0.7510.45
185_T209_N0.7460.45
54_E70_I0.7450.45
6_E83_M0.7440.45
10_L94_M0.7430.45
88_M94_M0.7420.44
39_V46_T0.7400.44
109_L143_F0.7390.44
81_L97_I0.7370.44
84_I133_I0.7290.43
71_S92_E0.7280.43
29_E34_L0.7220.43
151_L166_T0.7210.43
69_F172_R0.7190.42
6_E111_V0.7160.42
5_G209_N0.7140.42
104_R129_S0.7090.42
37_Y204_I0.7080.42
29_E89_P0.7050.41
126_Y194_G0.7040.41
96_R138_A0.7000.41
85_C103_V0.6990.41
48_I76_K0.6990.41
139_D145_S0.6980.41
8_V57_V0.6940.40
200_L204_I0.6940.40
25_A148_S0.6920.40
113_I152_I0.6910.40
27_S37_Y0.6890.40
100_R127_N0.6880.40
174_F186_L0.6850.40
128_I188_Y0.6850.40
172_R185_T0.6850.40
119_E169_V0.6750.39
28_I102_Y0.6720.38
103_V203_C0.6710.38
147_E170_V0.6700.38
48_I151_L0.6670.38
37_Y96_R0.6660.38
199_L212_R0.6660.38
81_L153_I0.6660.38
171_R204_I0.6600.37
135_V184_M0.6590.37
66_P197_Q0.6580.37
149_L170_V0.6520.37
22_K105_T0.6480.37
197_Q204_I0.6420.36
28_I199_L0.6410.36
36_A39_V0.6390.36
169_V198_A0.6380.36
15_E50_H0.6370.36
71_S105_T0.6350.35
97_I172_R0.6300.35
67_Y181_K0.6280.35
8_V23_S0.6270.35
12_Y19_K0.6270.35
98_Q204_I0.6260.35
25_A92_E0.6240.35
103_V197_Q0.6230.34
115_P149_L0.6210.34
44_G123_T0.6160.34
59_F76_K0.6130.34
107_A202_Y0.6110.34
30_N76_K0.6090.33
33_L168_A0.6080.33
36_A48_I0.6050.33
178_K198_A0.6040.33
8_V69_F0.6040.33
109_L125_S0.6000.33
125_S134_A0.5970.32
24_K37_Y0.5960.32
102_Y206_R0.5960.32
137_L173_I0.5940.32
46_T99_R0.5930.32
110_D163_Q0.5920.32
75_G166_T0.5880.32
168_A210_K0.5870.32
21_A49_L0.5860.32
77_V81_L0.5850.32
171_R201_Q0.5830.31
25_A189_S0.5820.31
73_I86_L0.5820.31
193_A199_L0.5810.31
78_K158_E0.5790.31
69_F103_V0.5770.31
10_L68_R0.5770.31
116_G213_K0.5770.31
34_L78_K0.5770.31
22_K99_R0.5740.31
109_L121_I0.5710.30
83_M166_T0.5620.30
27_S103_V0.5610.30
132_G188_Y0.5600.30
96_R102_Y0.5600.30
22_K153_I0.5590.30
187_E205_R0.5580.30
84_I134_A0.5560.29
128_I153_I0.5530.29
135_V175_N0.5530.29
10_L86_L0.5520.29
46_T211_R0.5520.29
123_T165_E0.5520.29
59_F94_M0.5510.29
127_N134_A0.5500.29
21_A204_I0.5490.29
117_N147_E0.5480.29
170_V185_T0.5470.29
103_V204_I0.5460.29
11_E56_T0.5440.28
140_G182_R0.5400.28
136_V181_K0.5400.28
8_V189_S0.5380.28
104_R127_N0.5360.28
79_D116_G0.5360.28
156_P184_M0.5360.28
27_S183_K0.5320.28
85_C199_L0.5280.27
112_Q195_D0.5260.27
12_Y53_M0.5240.27
131_G204_I0.5230.27
5_G45_R0.5220.27
98_Q103_V0.5220.27
170_V194_G0.5220.27
143_F184_M0.5190.27
57_V112_Q0.5190.27
102_Y130_A0.5190.27
12_Y17_E0.5180.27
171_R186_L0.5130.26
113_I123_T0.5130.26
119_E188_Y0.5120.26
26_V48_I0.5110.26
68_R95_K0.5070.26
199_L204_I0.5060.26
23_S204_I0.5050.26
109_L183_K0.5050.26
153_I157_E0.5040.26
165_E168_A0.5040.26
128_I197_Q0.5030.26
109_L202_Y0.5020.26
124_L175_N0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2rdeA 2 0.9447 100 0.379 Contact Map
3kyfA 2 0.9124 100 0.409 Contact Map
4rt1A 2 0.4885 99.7 0.663 Contact Map
4i86A 1 0.4654 99.7 0.667 Contact Map
4p02A 1 0.9078 99.5 0.707 Contact Map
3ph1A 3 0.7419 99.5 0.71 Contact Map
2l74A 1 0.5253 99.4 0.729 Contact Map
1ywuA 1 0.5346 99.3 0.737 Contact Map
3cnrA 1 0.4194 98.8 0.787 Contact Map
2l1tA 1 0.447 98.1 0.831 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.013 seconds.