DACF - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DACF - D-alanyl-D-alanine carboxypeptidase DacF

UniProt:	P38422	Sequences: MKRLLSTLLIGIMLLTFAPSAFAKQDGKRTSELAHEAKSAVLIERDTGKVLYNKNSNERLAPASMTKIMTMLLIMEALDKGKIKMSDKVRTSEHAASMGGSQIFLEPGEEMTVKEMLKGIAIASGNDASVAMAEFISGSEEEFVKKMNKKAKELGLKNTSFKNPTGLTEEGHYSSAYDMAIMAKELLKYESITKFTGTYEDYLRENTDKKFWLVNTNRLIKFYPGVDGVKTGYTGEAKYCLTASAKKGNMRAIAVVFGASTPKERNAQVTKMLDFAFSQYETHPLYKRNQTVAKVKVKKGKQKFIELTTSEPISILTKKGEDMNDVKKEIKMKDNISAPIQKGQELGTLVLKKDGEVLAESPVAAKEDMKKAGFITFLKRTMGDWTKFK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	389 (362)
Sequences:	4242 (3349)
Seq/√Len:	176.0

ECOLI - DACD DACC DACA PBP7
BACSU - DACF DACA DACB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
57_N	177_Y	3.765	1.00
53_N	56_S	3.736	1.00
137_S	146_K	3.006	1.00
113_V	132_M	2.948	1.00
92_S	134_E	2.944	1.00
88_K	110_E	2.940	1.00
74_I	132_M	2.790	1.00
348_T	360_E	2.741	1.00
42_L	276_A	2.633	1.00
55_N	58_E	2.574	1.00
183_A	229_V	2.558	1.00
87_D	135_F	2.550	1.00
227_D	251_R	2.541	1.00
93_E	107_P	2.493	1.00
156_L	182_M	2.482	1.00
150_K	153_E	2.446	1.00
252_A	276_A	2.433	1.00
345_E	362_P	2.420	1.00
118_K	198_T	2.411	1.00
76_E	150_K	2.383	1.00
120_I	132_M	2.372	1.00
225_G	247_K	2.339	1.00
59_R	173_Y	2.328	1.00
72_L	185_E	2.318	1.00
227_D	244_S	2.264	1.00
112_T	115_E	2.216	1.00
119_G	125_G	2.190	1.00
68_I	242_T	2.176	1.00
340_I	365_A	2.124	1.00
57_N	158_N	2.082	1.00
120_I	129_S	2.074	1.00
140_E	164_P	2.055	1.00
40_A	52_Y	2.050	1.00
69_M	159_T	2.045	1.00
284_P	287_K	2.032	1.00
246_K	249_N	1.992	1.00
45_R	253_I	1.991	1.00
90_R	110_E	1.964	1.00
302_Q	367_E	1.958	1.00
177_Y	181_I	1.948	1.00
254_A	269_V	1.928	1.00
142_E	145_K	1.911	1.00
308_T	366_K	1.889	1.00
139_S	142_E	1.849	1.00
336_I	346_L	1.815	1.00
352_K	357_V	1.815	1.00
145_K	149_K	1.803	1.00
59_R	158_N	1.802	1.00
69_M	151_A	1.785	1.00
245_A	277_F	1.781	1.00
268_Q	271_K	1.751	1.00
183_A	242_T	1.737	1.00
89_V	135_F	1.729	1.00
137_S	142_E	1.706	1.00
89_V	131_A	1.692	1.00
91_T	131_A	1.686	1.00
154_L	185_E	1.673	1.00
345_E	348_T	1.648	1.00
357_V	360_E	1.644	1.00
88_K	112_T	1.633	1.00
65_M	242_T	1.624	1.00
86_S	114_K	1.621	1.00
42_L	252_A	1.614	1.00
94_H	134_E	1.614	1.00
92_S	95_A	1.610	1.00
39_S	60_L	1.609	1.00
39_S	176_A	1.596	1.00
344_Q	365_A	1.592	1.00
329_E	352_K	1.589	1.00
156_L	181_I	1.588	1.00
65_M	179_M	1.578	1.00
159_T	174_S	1.573	1.00
70_T	129_S	1.572	1.00
71_M	121_A	1.571	1.00
191_S	194_K	1.564	1.00
310_S	362_P	1.561	1.00
44_E	250_M	1.554	1.00
160_S	173_Y	1.545	1.00
294_K	304_F	1.534	1.00
234_T	237_A	1.524	1.00
346_L	365_A	1.516	1.00
185_E	188_K	1.511	1.00
71_M	120_I	1.505	1.00
184_K	253_I	1.498	1.00
122_I	198_T	1.477	1.00
38_K	258_G	1.456	1.00
350_V	360_E	1.446	1.00
77_A	82_K	1.444	1.00
93_E	97_S	1.444	1.00
223_Y	274_D	1.442	1.00
176_A	257_F	1.439	1.00
149_K	153_E	1.431	1.00
114_K	118_K	1.422	1.00
91_T	105_L	1.421	1.00
168_T	236_E	1.415	1.00
331_K	350_V	1.409	1.00
200_E	212_W	1.408	1.00
162_K	171_G	1.389	1.00
114_K	195_F	1.389	1.00
62_P	174_S	1.381	1.00
119_G	128_A	1.380	1.00
114_K	194_K	1.379	1.00
74_I	113_V	1.378	1.00
84_K	87_D	1.378	1.00
341_Q	368_D	1.373	1.00
305_I	365_A	1.370	1.00
83_I	135_F	1.366	1.00
41_V	177_Y	1.334	1.00
342_K	368_D	1.333	1.00
350_V	357_V	1.331	1.00
162_K	169_E	1.331	1.00
179_M	242_T	1.323	1.00
78_L	113_V	1.323	1.00
341_Q	344_Q	1.313	1.00
118_K	201_D	1.303	1.00
184_K	188_K	1.302	1.00
71_M	117_L	1.299	1.00
65_M	257_F	1.296	1.00
66_T	172_H	1.294	1.00
226_V	243_A	1.290	1.00
85_M	117_L	1.290	1.00
61_A	168_T	1.280	1.00
41_V	56_S	1.273	1.00
95_A	134_E	1.256	1.00
243_A	269_V	1.252	1.00
42_L	254_A	1.245	1.00
329_E	350_V	1.243	1.00
284_P	314_S	1.242	1.00
85_M	114_K	1.230	1.00
202_Y	212_W	1.221	1.00
118_K	122_I	1.217	1.00
98_M	130_V	1.217	1.00
193_T	244_S	1.216	1.00
146_K	149_K	1.215	1.00
330_I	363_V	1.213	1.00
281_E	319_K	1.210	1.00
61_A	236_E	1.207	1.00
103_I	119_G	1.204	1.00
79_D	191_S	1.204	1.00
151_A	156_L	1.198	1.00
244_S	251_R	1.190	1.00
331_K	348_T	1.181	1.00
72_L	150_K	1.181	1.00
246_K	251_R	1.178	1.00
41_V	50_V	1.172	1.00
142_E	146_K	1.164	1.00
39_S	55_N	1.157	1.00
199_Y	221_K	1.157	1.00
77_A	146_K	1.156	1.00
124_S	230_K	1.148	1.00
40_A	54_K	1.140	1.00
306_E	366_K	1.136	1.00
372_A	376_T	1.128	1.00
68_I	229_V	1.126	1.00
223_Y	226_V	1.120	1.00
237_A	240_C	1.119	1.00
256_V	269_V	1.109	1.00
56_S	177_Y	1.108	1.00
150_K	185_E	1.105	1.00
261_T	264_E	1.102	1.00
365_A	368_D	1.102	1.00
287_K	290_Q	1.100	1.00
73_L	77_A	1.094	1.00
74_I	120_I	1.092	1.00
287_K	312_P	1.091	1.00
144_V	164_P	1.086	1.00
57_N	175_S	1.086	1.00
68_I	183_A	1.081	1.00
48_G	184_K	1.064	1.00
259_A	268_Q	1.060	1.00
270_T	274_D	1.059	1.00
327_K	352_K	1.058	1.00
43_I	180_A	1.053	1.00
301_K	370_K	1.051	1.00
83_I	113_V	1.049	1.00
144_V	148_N	1.040	0.99
295_V	307_L	1.039	0.99
162_K	172_H	1.032	0.99
37_A	259_A	1.021	0.99
321_E	325_D	1.020	0.99
94_H	141_E	1.017	0.99
83_I	132_M	1.015	0.99
284_P	312_P	1.010	0.99
245_A	273_L	1.010	0.99
226_V	273_L	1.009	0.99
129_S	164_P	0.997	0.99
196_T	229_V	0.997	0.99
243_A	273_L	0.995	0.99
300_G	338_A	0.993	0.99
77_A	136_I	0.993	0.99
373_G	376_T	0.990	0.99
310_S	364_A	0.983	0.99
318_K	321_E	0.983	0.99
193_T	251_R	0.979	0.99
247_K	277_F	0.975	0.99
294_K	306_E	0.965	0.99
74_I	83_I	0.963	0.99
282_T	316_L	0.962	0.99
96_A	107_P	0.958	0.99
91_T	111_M	0.957	0.99
187_L	193_T	0.952	0.99
62_P	257_F	0.951	0.99
124_S	231_T	0.948	0.99
46_D	282_T	0.946	0.99
59_R	175_S	0.942	0.99
38_K	60_L	0.940	0.99
75_M	192_I	0.936	0.99
151_A	182_M	0.936	0.99
79_D	87_D	0.934	0.99
307_L	346_L	0.933	0.99
372_A	380_R	0.932	0.99
158_N	175_S	0.929	0.99
286_Y	309_T	0.928	0.99
73_L	150_K	0.927	0.99
73_L	136_I	0.926	0.99
44_E	282_T	0.922	0.99
86_S	112_T	0.921	0.99
180_A	255_V	0.919	0.99
46_D	251_R	0.918	0.99
223_Y	245_A	0.909	0.99
89_V	113_V	0.906	0.99
94_H	140_E	0.903	0.99
157_K	177_Y	0.902	0.99
68_I	186_L	0.902	0.99
194_K	197_G	0.901	0.99
247_K	274_D	0.896	0.98
136_I	146_K	0.896	0.98
242_T	255_V	0.896	0.98
130_V	140_E	0.893	0.98
106_E	109_E	0.892	0.98
225_G	274_D	0.891	0.98
275_F	280_Y	0.891	0.98
305_I	340_I	0.891	0.98
306_E	367_E	0.888	0.98
260_S	264_E	0.885	0.98
149_K	152_K	0.885	0.98
160_S	171_G	0.883	0.98
78_L	192_I	0.879	0.98
72_L	189_Y	0.879	0.98
179_M	257_F	0.877	0.98
78_L	83_I	0.874	0.98
44_E	316_L	0.874	0.98
305_I	369_M	0.872	0.98
282_T	314_S	0.871	0.98
79_D	189_Y	0.871	0.98
125_G	128_A	0.868	0.98
46_D	314_S	0.864	0.98
204_R	210_K	0.860	0.98
352_K	355_G	0.857	0.98
91_T	116_M	0.853	0.98
313_I	359_A	0.852	0.98
288_R	312_P	0.850	0.98
13_M	16_T	0.850	0.98
371_K	377_F	0.848	0.98
223_Y	270_T	0.847	0.98
246_K	277_F	0.847	0.98
90_R	135_F	0.845	0.98
121_A	196_T	0.842	0.98
229_V	244_S	0.842	0.98
105_L	131_A	0.841	0.98
328_K	351_L	0.841	0.98
168_T	234_T	0.839	0.98
111_M	115_E	0.838	0.98
36_E	268_Q	0.836	0.98
203_L	213_L	0.835	0.98
85_M	195_F	0.834	0.98
111_M	116_M	0.832	0.98
74_I	136_I	0.828	0.97
275_F	279_Q	0.827	0.97
192_I	196_T	0.824	0.97
34_A	54_K	0.823	0.97
344_Q	368_D	0.823	0.97
63_A	237_A	0.822	0.97
148_N	160_S	0.820	0.97
313_I	361_S	0.819	0.97
193_T	196_T	0.817	0.97
68_I	121_A	0.816	0.97
64_S	230_K	0.815	0.97
181_I	184_K	0.815	0.97
339_P	369_M	0.813	0.97
38_K	58_E	0.807	0.97
43_I	184_K	0.807	0.97
200_E	214_V	0.803	0.97
179_M	183_A	0.801	0.97
116_M	128_A	0.800	0.97
349_L	361_S	0.800	0.97
254_A	273_L	0.799	0.97
69_M	147_M	0.796	0.97
174_S	179_M	0.794	0.97
81_G	84_K	0.793	0.97
75_M	189_Y	0.793	0.97
41_V	53_N	0.792	0.97
186_L	229_V	0.792	0.97
73_L	76_E	0.792	0.97
41_V	255_V	0.791	0.97
41_V	180_A	0.790	0.97
241_L	269_V	0.784	0.97
115_E	204_R	0.781	0.96
340_I	346_L	0.780	0.96
233_Y	239_Y	0.777	0.96
102_Q	105_L	0.775	0.96
115_E	118_K	0.772	0.96
291_T	306_E	0.770	0.96
326_V	353_K	0.768	0.96
161_F	179_M	0.768	0.96
109_E	211_F	0.768	0.96
283_H	322_D	0.762	0.96
51_L	280_Y	0.761	0.96
218_R	266_N	0.757	0.96
147_M	151_A	0.753	0.96
256_V	259_A	0.753	0.96
217_N	243_A	0.750	0.96
325_D	354_D	0.749	0.95
234_T	240_C	0.748	0.95
14_L	17_F	0.746	0.95
297_V	338_A	0.744	0.95
141_E	145_K	0.744	0.95
152_K	157_K	0.743	0.95
204_R	211_F	0.741	0.95
101_S	125_G	0.741	0.95
183_A	228_G	0.734	0.95
148_N	161_F	0.734	0.95
187_L	227_D	0.731	0.95
187_L	251_R	0.731	0.95
259_A	264_E	0.729	0.95
201_D	213_L	0.729	0.95
336_I	340_I	0.728	0.95
151_A	154_L	0.727	0.95
117_L	195_F	0.724	0.95
217_N	241_L	0.720	0.94
69_M	73_L	0.719	0.94
213_L	216_T	0.719	0.94
151_A	161_F	0.718	0.94
111_M	203_L	0.717	0.94
69_M	161_F	0.717	0.94
82_K	146_K	0.717	0.94
118_K	195_F	0.713	0.94
146_K	150_K	0.713	0.94
75_M	117_L	0.712	0.94
65_M	240_C	0.711	0.94
297_V	300_G	0.710	0.94
69_M	156_L	0.710	0.94
309_T	363_V	0.708	0.94
64_S	67_K	0.706	0.94
202_Y	210_K	0.702	0.94
186_L	192_I	0.700	0.94
39_S	257_F	0.700	0.94
300_G	369_M	0.699	0.94
78_L	132_M	0.696	0.93
123_A	216_T	0.693	0.93
223_Y	273_L	0.690	0.93
61_A	169_E	0.689	0.93
78_L	85_M	0.689	0.93
64_S	124_S	0.687	0.93
353_K	356_E	0.686	0.93
154_L	182_M	0.684	0.93
89_V	116_M	0.683	0.93
254_A	272_M	0.681	0.93
71_M	75_M	0.680	0.93
374_F	378_L	0.679	0.93
71_M	196_T	0.678	0.92
73_L	147_M	0.678	0.92
60_L	257_F	0.678	0.92
100_G	127_D	0.672	0.92
186_L	189_Y	0.671	0.92
103_I	123_A	0.670	0.92
343_G	365_A	0.669	0.92
264_E	267_A	0.662	0.92
103_I	111_M	0.659	0.91
250_M	282_T	0.657	0.91
53_N	177_Y	0.656	0.91
158_N	178_D	0.656	0.91
85_M	88_K	0.655	0.91
250_M	280_Y	0.654	0.91
18_A	21_A	0.654	0.91
92_S	131_A	0.654	0.91
353_K	358_L	0.650	0.91
121_A	192_I	0.650	0.91
192_I	229_V	0.648	0.91
307_L	363_V	0.648	0.91
98_M	167_L	0.646	0.91
64_S	232_G	0.645	0.90
243_A	254_A	0.645	0.90
159_T	178_D	0.643	0.90
83_I	89_V	0.642	0.90
69_M	182_M	0.641	0.90
225_G	245_A	0.640	0.90
35_H	40_A	0.639	0.90
68_I	182_M	0.637	0.90
327_K	355_G	0.637	0.90
115_E	201_D	0.634	0.90
144_V	159_T	0.633	0.90
76_E	153_E	0.631	0.90
123_A	213_L	0.629	0.89
63_A	66_T	0.627	0.89
49_K	316_L	0.626	0.89
328_K	349_L	0.626	0.89
330_I	349_L	0.625	0.89
148_N	152_K	0.624	0.89
53_N	57_N	0.624	0.89
94_H	98_M	0.622	0.89
122_I	201_D	0.622	0.89
162_K	170_E	0.621	0.89
43_I	253_I	0.620	0.89
26_D	29_R	0.619	0.89
49_K	356_E	0.617	0.88
78_L	136_I	0.617	0.88
73_L	159_T	0.614	0.88
271_K	274_D	0.613	0.88
300_G	339_P	0.611	0.88
99_G	102_Q	0.610	0.88
116_M	132_M	0.610	0.88
83_I	87_D	0.607	0.88
196_T	244_S	0.606	0.88
264_E	268_Q	0.605	0.87
196_T	228_G	0.604	0.87
157_K	181_I	0.603	0.87
43_I	181_I	0.599	0.87
44_E	47_T	0.599	0.87
67_K	126_N	0.596	0.87
75_M	191_S	0.595	0.87
309_T	313_I	0.595	0.87
73_L	146_K	0.594	0.87
233_Y	262_P	0.594	0.87
179_M	240_C	0.590	0.86
131_A	135_F	0.588	0.86
136_I	144_V	0.588	0.86
78_L	87_D	0.588	0.86
62_P	66_T	0.587	0.86
283_H	317_T	0.587	0.86
326_V	358_L	0.586	0.86
256_V	272_M	0.585	0.86
63_A	231_T	0.583	0.85
299_K	337_S	0.580	0.85
37_A	268_Q	0.580	0.85
65_M	68_I	0.578	0.85
223_Y	247_K	0.577	0.85
241_L	256_V	0.576	0.85
301_K	376_T	0.576	0.85
140_E	144_V	0.575	0.85
66_T	174_S	0.575	0.85
241_L	254_A	0.574	0.85
186_L	196_T	0.574	0.85
217_N	220_I	0.574	0.85
231_T	265_R	0.573	0.85
174_S	178_D	0.573	0.85
289_N	309_T	0.573	0.85
150_K	154_L	0.571	0.84
33_L	275_F	0.571	0.84
239_Y	262_P	0.570	0.84
10_I	16_T	0.569	0.84
50_V	53_N	0.569	0.84
49_K	321_E	0.568	0.84
376_T	379_K	0.567	0.84
156_L	178_D	0.567	0.84
42_L	272_M	0.565	0.84
285_L	315_I	0.565	0.84
226_V	245_A	0.565	0.84
16_T	20_S	0.565	0.84
62_P	179_M	0.564	0.84
216_T	233_Y	0.563	0.83
64_S	231_T	0.563	0.83
98_M	102_Q	0.563	0.83
272_M	276_A	0.561	0.83
9_L	12_I	0.560	0.83
75_M	196_T	0.560	0.83
376_T	380_R	0.559	0.83
160_S	172_H	0.559	0.83
279_Q	318_K	0.559	0.83
9_L	16_T	0.557	0.83
222_F	270_T	0.555	0.83
10_I	18_A	0.554	0.83
348_T	362_P	0.553	0.82
168_T	237_A	0.553	0.82
72_L	154_L	0.553	0.82
273_L	276_A	0.551	0.82
133_A	140_E	0.551	0.82
114_K	191_S	0.551	0.82
45_R	184_K	0.549	0.82
219_L	241_L	0.549	0.82
119_G	213_L	0.547	0.82
76_E	189_Y	0.547	0.82
100_G	104_F	0.544	0.81
63_A	124_S	0.543	0.81
172_H	240_C	0.543	0.81
62_P	172_H	0.542	0.81
286_Y	351_L	0.541	0.81
59_R	174_S	0.541	0.81
63_A	232_G	0.541	0.81
192_I	195_F	0.540	0.81
241_L	266_N	0.540	0.81
239_Y	265_R	0.537	0.81
45_R	188_K	0.536	0.80
227_D	246_K	0.535	0.80
223_Y	277_F	0.535	0.80
109_E	204_R	0.535	0.80
286_Y	349_L	0.533	0.80
77_A	83_I	0.532	0.80
55_N	60_L	0.532	0.80
103_I	125_G	0.532	0.80
286_Y	289_N	0.531	0.80
165_T	168_T	0.530	0.80
117_L	121_A	0.530	0.80
111_M	119_G	0.527	0.79
338_A	369_M	0.527	0.79
193_T	227_D	0.527	0.79
181_I	185_E	0.524	0.79
317_T	324_N	0.524	0.79
35_H	268_Q	0.524	0.79
102_Q	127_D	0.523	0.79
373_G	377_F	0.523	0.79
321_E	353_K	0.522	0.79
12_I	19_P	0.521	0.79
285_L	351_L	0.521	0.79
317_T	326_V	0.520	0.78
163_N	168_T	0.520	0.78
75_M	195_F	0.519	0.78
101_S	230_K	0.518	0.78
103_I	213_L	0.518	0.78
345_E	364_A	0.517	0.78
187_L	229_V	0.517	0.78
143_F	147_M	0.517	0.78
43_I	48_G	0.514	0.78
179_M	182_M	0.514	0.78
283_H	286_Y	0.513	0.77
68_I	75_M	0.512	0.77
375_I	379_K	0.511	0.77
297_V	305_I	0.510	0.77
197_G	227_D	0.509	0.77
298_K	335_N	0.509	0.77
289_N	308_T	0.509	0.77
101_S	231_T	0.507	0.77
29_R	33_L	0.506	0.77
71_M	186_L	0.506	0.77
193_T	197_G	0.506	0.77
357_V	361_S	0.505	0.76
122_I	195_F	0.505	0.76
250_M	316_L	0.505	0.76
199_Y	214_V	0.504	0.76
70_T	143_F	0.504	0.76
14_L	20_S	0.503	0.76
109_E	203_L	0.502	0.76
147_M	161_F	0.500	0.76

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mzfA	1	0.8895	100	0.248	Contact Map
3itaA	1	0.8766	100	0.263	Contact Map
4k91A	1	0.8792	100	0.265	Contact Map
3a3jA	1	0.8663	100	0.277	Contact Map
3mfdA	1	0.8226	100	0.286	Contact Map
1xp4A	3	0.8483	100	0.287	Contact Map
3hunA	1	0.8072	100	0.379	Contact Map
1tvfA	1	0.8355	100	0.41	Contact Map
4pprA	1	0.7481	100	0.482	Contact Map
4ryeA	1	0.6658	100	0.488	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0115 seconds.