NADB - BACSU - GREMLIN Contacts

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NADB - L-aspartate oxidase

UniProt:	P38032	Sequences: MSKKTIAVIGSGAAALSLAAAFPPSYEVTVITKKSVKNSNSVYAQGGIAAAYAKDDSIEAHLEDTLYAGCGHNNLAIVADVLHDGKMMVQSLLERGFPFDRNERGGVCLGREGAHSYNRIFHAGGDATGRLLIDYLLKRINSKIKLIENETAADLLIEDGRCIGVMTKDSKGRLKVRHADEVVLAAGGCGNLFLHHTNDLTVTGDGLSLAYRAGAELTDLEFTQFHPTLLVKNGVSYGLVSEAVRGEGGCLVDENGRRIMAERHPLGDLAPRDIVSRVIHEEMAKGNRVYIDFSAISDFETRFPTITAICEKAGIDIHSGKIPVAPGMHFLMGGVSVNRWGETTVPGLYAIGETACSGLHGANRLASNSLLEALVFGKRAAEHIIQKPVYNRQYQSGLETSVFYEVPDIEGHELQSKMTSHMSILREQSSLIELSIWLHTLPFQEVNVKDITIRQMELSHLWQTAKLMTFSALLREESRGAHFRTDFPHAEVSWQGRQIVHTKKGTKIRKNEGIWNNESFTAEKITESLFS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	531 (492)
Sequences:	5300 (2712)
Seq/√Len:	122.3

ECOLI - FRDA SDHA NADB
BACSU - NADB SDHA
HALSA - Q9HQ66 NADB
SULSO - Q97W79 NADB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
7_A	165_V	4.074	1.00
338_N	342_E	4.059	1.00
152_A	209_L	3.453	1.00
253_D	257_R	3.229	1.00
79_A	83_H	3.207	1.00
73_N	78_V	3.203	1.00
4_K	29_T	3.111	1.00
81_V	359_L	3.002	1.00
257_R	262_E	2.954	1.00
18_L	183_V	2.916	1.00
422_M	469_T	2.892	1.00
428_Q	476_E	2.827	1.00
442_P	466_K	2.731	1.00
253_D	282_E	2.627	1.00
349_Y	383_H	2.623	1.00
421_H	433_E	2.573	1.00
240_V	244_V	2.569	1.00
258_R	268_D	2.537	1.00
261_A	267_G	2.494	1.00
147_I	177_R	2.479	1.00
84_D	379_R	2.451	1.00
435_S	469_T	2.401	1.00
13_A	373_A	2.389	1.00
9_I	165_V	2.346	1.00
211_Y	467_L	2.341	1.00
139_R	142_S	2.314	1.00
476_E	487_F	2.312	1.00
427_E	485_T	2.300	1.00
428_Q	432_I	2.295	1.00
27_E	145_K	2.275	1.00
18_L	351_I	2.228	1.00
413_E	437_W	2.227	1.00
29_T	147_I	2.197	1.00
22_F	384_I	2.172	1.00
422_M	434_L	2.164	1.00
13_A	41_S	2.145	1.00
342_E	383_H	2.128	1.00
432_I	473_L	2.127	1.00
80_D	379_R	2.125	1.00
335_V	354_T	2.087	1.00
60_A	117_Y	2.078	1.00
31_I	167_T	2.076	1.00
439_H	466_K	2.075	1.00
350_A	354_T	2.060	1.00
154_D	212_R	2.058	1.00
207_L	217_L	2.041	1.00
229_L	327_G	2.030	1.00
22_F	381_A	2.022	1.00
252_V	321_K	2.003	1.00
81_V	376_F	1.982	1.00
216_E	344_T	1.973	1.00
294_S	321_K	1.958	1.00
131_L	134_D	1.950	1.00
279_I	289_V	1.939	1.00
184_L	354_T	1.920	1.00
184_L	335_V	1.904	1.00
427_E	430_S	1.895	1.00
167_T	177_R	1.889	1.00
307_T	311_E	1.875	1.00
417_K	434_L	1.848	1.00
5_T	180_D	1.840	1.00
422_M	431_L	1.835	1.00
343_T	350_A	1.819	1.00
438_L	469_T	1.807	1.00
102_N	106_G	1.800	1.00
418_M	422_M	1.797	1.00
29_T	177_R	1.796	1.00
41_S	133_I	1.784	1.00
216_E	336_S	1.784	1.00
183_V	384_I	1.778	1.00
160_G	346_P	1.751	1.00
88_M	91_S	1.748	1.00
252_V	294_S	1.742	1.00
189_C	331_L	1.738	1.00
250_C	258_R	1.730	1.00
435_S	466_K	1.720	1.00
75_L	79_A	1.705	1.00
210_A	335_V	1.704	1.00
70_C	490_A	1.699	1.00
212_R	460_H	1.698	1.00
69_G	73_N	1.677	1.00
38_N	43_Y	1.672	1.00
77_I	339_R	1.664	1.00
186_A	206_G	1.660	1.00
169_D	175_K	1.657	1.00
161_R	347_G	1.654	1.00
341_G	380_A	1.633	1.00
62_L	79_A	1.626	1.00
217_L	220_L	1.616	1.00
300_E	307_T	1.615	1.00
414_L	438_L	1.605	1.00
192_L	468_M	1.603	1.00
244_V	249_G	1.578	1.00
162_C	182_V	1.576	1.00
340_W	383_H	1.568	1.00
51_A	58_I	1.567	1.00
140_I	146_L	1.564	1.00
380_A	384_I	1.559	1.00
281_E	285_K	1.533	1.00
435_S	470_F	1.520	1.00
33_K	205_D	1.511	1.00
300_E	318_H	1.491	1.00
6_I	22_F	1.478	1.00
417_K	437_W	1.474	1.00
41_S	373_A	1.472	1.00
337_V	355_A	1.467	1.00
62_L	66_L	1.465	1.00
58_I	62_L	1.460	1.00
442_P	463_Q	1.459	1.00
413_E	444_Q	1.455	1.00
241_S	244_V	1.454	1.00
210_A	215_A	1.448	1.00
88_M	378_K	1.446	1.00
33_K	203_T	1.446	1.00
405_E	444_Q	1.444	1.00
197_T	229_L	1.443	1.00
4_K	7_A	1.442	1.00
77_I	81_V	1.429	1.00
434_L	469_T	1.420	1.00
293_F	296_I	1.413	1.00
14_A	351_I	1.410	1.00
428_Q	484_R	1.407	1.00
58_I	83_H	1.403	1.00
93_L	107_V	1.401	1.00
21_A	382_E	1.400	1.00
218_T	356_C	1.394	1.00
4_K	145_K	1.387	1.00
33_K	457_E	1.385	1.00
48_I	132_L	1.378	1.00
332_M	481_A	1.376	1.00
435_S	473_L	1.370	1.00
421_H	430_S	1.369	1.00
466_K	470_F	1.360	1.00
241_S	306_I	1.355	1.00
179_A	182_V	1.353	1.00
150_E	169_D	1.350	1.00
258_R	261_A	1.349	1.00
421_H	434_L	1.347	1.00
205_D	460_H	1.345	1.00
90_Q	94_E	1.343	1.00
437_W	440_T	1.340	1.00
49_A	367_S	1.338	1.00
193_F	422_M	1.333	1.00
156_L	176_V	1.332	1.00
147_I	150_E	1.327	1.00
218_T	336_S	1.326	1.00
9_I	184_L	1.324	1.00
84_D	87_M	1.323	1.00
4_K	27_E	1.322	1.00
6_I	26_Y	1.309	1.00
16_L	140_I	1.309	1.00
383_H	387_K	1.304	1.00
190_G	328_M	1.295	1.00
189_C	223_T	1.295	1.00
428_Q	473_L	1.294	1.00
183_V	351_I	1.289	1.00
161_R	346_P	1.289	1.00
152_A	165_V	1.289	1.00
280_H	284_A	1.285	1.00
184_L	348_L	1.285	1.00
181_E	387_K	1.284	1.00
307_T	318_H	1.276	1.00
58_I	82_L	1.275	1.00
84_D	88_M	1.267	1.00
298_D	318_H	1.266	1.00
6_I	183_V	1.264	1.00
277_R	483_F	1.262	1.00
155_L	162_C	1.255	1.00
150_E	167_T	1.251	0.99
152_A	167_T	1.246	0.99
184_L	210_A	1.246	0.99
31_I	165_V	1.244	0.99
30_V	146_L	1.235	0.99
491_E	494_W	1.229	0.99
77_I	359_L	1.225	0.99
85_G	371_L	1.221	0.99
140_I	144_I	1.218	0.99
156_L	166_M	1.218	0.99
4_K	147_I	1.213	0.99
17_S	21_A	1.210	0.99
416_S	420_S	1.210	0.99
63_E	67_Y	1.208	0.99
61_H	368_N	1.207	0.99
251_L	324_V	1.206	0.99
49_A	115_H	1.203	0.99
428_Q	487_F	1.203	0.99
11_S	32_T	1.198	0.99
422_M	468_M	1.196	0.99
97_F	131_L	1.193	0.99
349_Y	387_K	1.189	0.99
377_G	381_A	1.188	0.99
472_A	482_H	1.184	0.99
91_S	378_K	1.174	0.99
97_F	132_L	1.165	0.99
16_L	30_V	1.164	0.99
154_D	209_L	1.163	0.99
62_L	82_L	1.159	0.99
21_A	378_K	1.154	0.99
476_E	494_W	1.150	0.99
194_L	416_S	1.149	0.99
250_C	268_D	1.148	0.99
221_E	475_R	1.145	0.99
20_A	140_I	1.143	0.99
52_Y	121_F	1.138	0.99
282_E	285_K	1.126	0.99
207_L	331_L	1.124	0.99
212_R	463_Q	1.123	0.99
115_H	367_S	1.122	0.99
59_E	63_E	1.121	0.99
263_R	278_V	1.119	0.99
21_A	381_A	1.119	0.99
18_L	380_A	1.117	0.99
381_A	385_I	1.110	0.99
59_E	79_A	1.109	0.99
421_H	437_W	1.107	0.99
100_D	122_H	1.103	0.99
150_E	175_K	1.098	0.99
189_C	468_M	1.094	0.99
299_F	307_T	1.088	0.99
247_E	302_R	1.083	0.99
7_A	31_I	1.082	0.99
80_D	339_R	1.080	0.99
335_V	350_A	1.080	0.99
261_A	268_D	1.078	0.98
18_L	384_I	1.074	0.98
80_D	376_F	1.074	0.98
383_H	386_Q	1.072	0.98
9_I	152_A	1.070	0.98
207_L	464_T	1.068	0.98
492_V	495_Q	1.068	0.98
36_V	148_E	1.068	0.98
411_G	415_Q	1.061	0.98
61_H	65_T	1.059	0.98
378_K	382_E	1.059	0.98
48_I	89_V	1.055	0.98
215_A	348_L	1.052	0.98
315_I	320_G	1.047	0.98
95_R	139_R	1.044	0.98
342_E	387_K	1.042	0.98
384_I	388_P	1.041	0.98
6_I	384_I	1.039	0.98
151_T	456_M	1.037	0.98
62_L	75_L	1.036	0.98
30_V	140_I	1.035	0.98
432_I	435_S	1.034	0.98
80_D	84_D	1.030	0.98
359_L	376_F	1.029	0.98
97_F	135_Y	1.025	0.98
351_I	380_A	1.023	0.98
137_L	146_L	1.023	0.98
432_I	436_I	1.021	0.98
72_H	479_R	1.020	0.98
120_I	367_S	1.017	0.98
494_W	497_R	1.016	0.98
337_V	350_A	1.011	0.98
259_I	279_I	1.009	0.98
130_R	134_D	1.009	0.98
412_H	416_S	1.007	0.98
111_R	118_N	1.006	0.98
158_E	163_I	1.005	0.98
141_N	148_E	1.005	0.98
20_A	95_R	1.001	0.98
7_A	179_A	0.995	0.97
60_A	116_S	0.995	0.97
300_E	311_E	0.992	0.97
417_K	441_L	0.990	0.97
78_V	82_L	0.990	0.97
215_A	345_V	0.985	0.97
316_D	319_S	0.982	0.97
127_A	305_T	0.980	0.97
114_A	332_M	0.979	0.97
308_A	312_K	0.974	0.97
263_R	282_E	0.974	0.97
155_L	182_V	0.974	0.97
86_K	90_Q	0.972	0.97
166_M	174_L	0.972	0.97
23_P	26_Y	0.968	0.97
262_E	282_E	0.964	0.97
426_R	472_A	0.962	0.97
260_M	267_G	0.961	0.97
299_F	318_H	0.954	0.97
220_L	464_T	0.951	0.97
21_A	91_S	0.951	0.97
166_M	176_V	0.949	0.97
65_T	368_N	0.947	0.97
181_E	349_Y	0.946	0.97
252_V	292_D	0.943	0.96
62_L	78_V	0.943	0.96
36_V	137_L	0.941	0.96
381_A	384_I	0.940	0.96
5_T	27_E	0.939	0.96
417_K	421_H	0.938	0.96
115_H	120_I	0.938	0.96
411_G	461_L	0.937	0.96
249_G	293_F	0.936	0.96
118_N	247_E	0.936	0.96
414_L	458_L	0.935	0.96
66_L	78_V	0.932	0.96
7_A	29_T	0.932	0.96
437_W	441_L	0.931	0.96
439_H	470_F	0.930	0.96
107_V	121_F	0.929	0.96
157_I	162_C	0.927	0.96
315_I	322_I	0.926	0.96
290_Y	321_K	0.926	0.96
151_T	457_E	0.924	0.96
448_V	452_T	0.923	0.96
42_V	130_R	0.916	0.96
155_L	165_V	0.915	0.96
98_P	131_L	0.908	0.96
310_C	317_I	0.906	0.96
209_L	212_R	0.906	0.96
194_L	419_T	0.905	0.96
471_S	498_Q	0.905	0.96
425_L	485_T	0.903	0.95
490_A	494_W	0.900	0.95
220_L	468_M	0.897	0.95
232_K	313_A	0.895	0.95
66_L	73_N	0.894	0.95
414_L	462_W	0.891	0.95
110_G	247_E	0.890	0.95
40_N	43_Y	0.890	0.95
76_A	339_R	0.889	0.95
433_E	437_W	0.884	0.95
87_M	90_Q	0.880	0.95
181_E	388_P	0.879	0.95
337_V	357_S	0.878	0.95
138_K	142_S	0.876	0.95
91_S	95_R	0.871	0.95
250_C	295_A	0.870	0.94
309_I	312_K	0.869	0.94
158_E	161_R	0.865	0.94
101_R	107_V	0.865	0.94
17_S	88_M	0.863	0.94
22_F	26_Y	0.862	0.94
113_G	266_L	0.859	0.94
337_V	376_F	0.858	0.94
7_A	177_R	0.858	0.94
270_A	275_V	0.857	0.94
93_L	101_R	0.851	0.94
180_D	388_P	0.850	0.94
208_S	212_R	0.846	0.94
48_I	371_L	0.844	0.94
283_M	288_R	0.842	0.93
157_I	160_G	0.840	0.93
8_V	28_V	0.839	0.93
262_E	285_K	0.837	0.93
81_V	371_L	0.836	0.93
82_L	85_G	0.834	0.93
479_R	487_F	0.833	0.93
258_R	267_G	0.833	0.93
215_A	344_T	0.832	0.93
40_N	199_D	0.827	0.93
204_G	464_T	0.827	0.93
410_E	458_L	0.826	0.93
438_L	466_K	0.824	0.93
284_A	420_S	0.824	0.93
208_S	464_T	0.824	0.93
254_E	287_N	0.823	0.93
123_A	131_L	0.819	0.92
414_L	441_L	0.818	0.92
51_A	82_L	0.816	0.92
310_C	322_I	0.816	0.92
259_I	263_R	0.815	0.92
203_T	457_E	0.814	0.92
310_C	315_I	0.814	0.92
98_P	135_Y	0.813	0.92
259_I	268_D	0.811	0.92
493_S	496_G	0.809	0.92
185_A	351_I	0.808	0.92
19_A	144_I	0.806	0.92
50_A	89_V	0.801	0.92
252_V	290_Y	0.800	0.92
385_I	388_P	0.800	0.92
77_I	80_D	0.797	0.91
63_E	75_L	0.797	0.91
220_L	471_S	0.796	0.91
418_M	465_A	0.795	0.91
17_S	91_S	0.795	0.91
244_V	293_F	0.794	0.91
340_W	379_R	0.793	0.91
411_G	458_L	0.793	0.91
231_V	288_R	0.793	0.91
191_N	415_Q	0.790	0.91
431_L	469_T	0.789	0.91
479_R	488_P	0.788	0.91
84_D	378_K	0.786	0.91
18_L	22_F	0.785	0.91
40_N	202_V	0.783	0.91
66_L	75_L	0.779	0.91
435_S	439_H	0.779	0.91
181_E	384_I	0.778	0.90
58_I	86_K	0.777	0.90
180_D	392_R	0.772	0.90
169_D	173_R	0.767	0.90
181_E	347_G	0.766	0.90
283_M	286_G	0.766	0.90
160_G	345_V	0.765	0.90
7_A	182_V	0.764	0.90
263_R	281_E	0.763	0.90
193_F	468_M	0.761	0.89
289_V	324_V	0.760	0.89
223_T	468_M	0.759	0.89
217_L	467_L	0.759	0.89
180_D	393_Q	0.758	0.89
112_E	120_I	0.757	0.89
157_I	163_I	0.757	0.89
110_G	122_H	0.754	0.89
27_E	143_K	0.753	0.89
477_E	488_P	0.751	0.89
307_T	317_I	0.751	0.89
8_V	18_L	0.750	0.89
91_S	94_E	0.748	0.89
120_I	366_A	0.742	0.88
74_N	356_C	0.742	0.88
197_T	327_G	0.741	0.88
293_F	299_F	0.741	0.88
441_L	462_W	0.740	0.88
57_S	60_A	0.739	0.88
242_E	245_R	0.737	0.88
48_I	374_L	0.736	0.88
299_F	317_I	0.735	0.88
280_H	425_L	0.735	0.88
20_A	139_R	0.735	0.88
387_K	391_N	0.735	0.88
88_M	374_L	0.734	0.88
259_I	282_E	0.733	0.88
440_T	444_Q	0.732	0.88
183_V	380_A	0.731	0.88
190_G	196_H	0.726	0.87
337_V	341_G	0.726	0.87
191_N	461_L	0.723	0.87
316_D	320_G	0.723	0.87
112_E	367_S	0.721	0.87
490_A	493_S	0.719	0.87
6_I	25_S	0.718	0.87
264_H	271_P	0.718	0.87
259_I	262_E	0.718	0.87
425_L	483_F	0.716	0.86
189_C	207_L	0.715	0.86
60_A	63_E	0.713	0.86
478_S	483_F	0.713	0.86
342_E	349_Y	0.711	0.86
133_I	137_L	0.710	0.86
49_A	82_L	0.708	0.86
195_H	419_T	0.708	0.86
34_K	38_N	0.706	0.86
13_A	374_L	0.705	0.86
257_R	282_E	0.704	0.85
186_A	354_T	0.704	0.85
165_V	179_A	0.704	0.85
13_A	136_L	0.704	0.85
254_E	288_R	0.704	0.85
167_T	175_K	0.703	0.85
494_W	498_Q	0.702	0.85
351_I	377_G	0.702	0.85
31_I	177_R	0.700	0.85
270_A	274_I	0.700	0.85
470_F	474_L	0.700	0.85
36_V	146_L	0.699	0.85
20_A	144_I	0.698	0.85
342_E	346_P	0.697	0.85
5_T	26_Y	0.697	0.85
426_R	482_H	0.696	0.85
382_E	386_Q	0.696	0.85
134_D	138_K	0.695	0.85
278_V	282_E	0.694	0.85
98_P	101_R	0.693	0.85
49_A	120_I	0.693	0.85
228_T	245_R	0.693	0.85
92_L	132_L	0.692	0.85
157_I	346_P	0.690	0.84
222_F	475_R	0.690	0.84
206_G	354_T	0.688	0.84
161_R	387_K	0.687	0.84
281_E	425_L	0.687	0.84
367_S	372_E	0.686	0.84
208_S	460_H	0.686	0.84
446_V	450_D	0.686	0.84
421_H	469_T	0.686	0.84
183_V	388_P	0.682	0.84
409_I	413_E	0.681	0.84
163_I	178_H	0.681	0.84
442_P	462_W	0.681	0.84
273_D	277_R	0.679	0.83
98_P	134_D	0.677	0.83
192_L	464_T	0.676	0.83
93_L	121_F	0.676	0.83
43_Y	199_D	0.675	0.83
254_E	286_G	0.675	0.83
149_N	170_S	0.674	0.83
226_H	245_R	0.673	0.83
50_A	121_F	0.673	0.83
405_E	409_I	0.671	0.83
240_V	306_I	0.671	0.83
34_K	201_T	0.668	0.82
260_M	263_R	0.667	0.82
240_V	324_V	0.665	0.82
150_E	177_R	0.665	0.82
429_S	433_E	0.664	0.82
77_I	357_S	0.663	0.82
244_V	306_I	0.663	0.82
72_H	222_F	0.662	0.82
347_G	387_K	0.661	0.82
253_D	258_R	0.661	0.82
264_H	270_A	0.660	0.82
245_R	248_G	0.659	0.82
87_M	378_K	0.659	0.82
353_E	364_R	0.658	0.81
108_C	122_H	0.658	0.81
401_S	404_Y	0.657	0.81
51_A	61_H	0.656	0.81
219_D	497_R	0.656	0.81
8_V	384_I	0.655	0.81
311_E	318_H	0.654	0.81
351_I	381_A	0.651	0.81
433_E	436_I	0.651	0.81
190_G	331_L	0.650	0.81
463_Q	466_K	0.648	0.80
49_A	61_H	0.647	0.80
39_S	133_I	0.647	0.80
192_L	465_A	0.645	0.80
90_Q	93_L	0.645	0.80
190_G	198_N	0.644	0.80
453_I	457_E	0.643	0.80
31_I	147_I	0.643	0.80
208_S	463_Q	0.642	0.80
29_T	145_K	0.640	0.80
162_C	345_V	0.640	0.80
203_T	460_H	0.640	0.80
226_H	242_E	0.640	0.80
407_P	455_Q	0.640	0.80
430_S	434_L	0.639	0.80
412_H	415_Q	0.638	0.79
223_T	331_L	0.637	0.79
410_E	413_E	0.637	0.79
35_S	149_N	0.636	0.79
218_T	357_S	0.636	0.79
58_I	79_A	0.634	0.79
63_E	66_L	0.634	0.79
153_A	174_L	0.633	0.79
25_S	28_V	0.632	0.79
189_C	192_L	0.632	0.79
432_I	470_F	0.632	0.79
405_E	413_E	0.632	0.79
429_S	432_I	0.631	0.79
294_S	317_I	0.628	0.78
72_H	221_E	0.628	0.78
293_F	297_S	0.628	0.78
278_V	281_E	0.623	0.78
51_A	62_L	0.622	0.78
109_L	121_F	0.622	0.78
154_D	213_A	0.620	0.77
283_M	325_A	0.620	0.77
18_L	377_G	0.619	0.77
240_V	322_I	0.619	0.77
97_F	374_L	0.619	0.77
492_V	496_G	0.616	0.77
153_A	168_K	0.615	0.77
225_F	423_S	0.614	0.77
386_Q	390_Y	0.614	0.77
211_Y	463_Q	0.614	0.77
376_F	379_R	0.614	0.77
329_H	365_L	0.613	0.77
418_M	421_H	0.611	0.76
477_E	487_F	0.611	0.76
4_K	177_R	0.610	0.76
309_I	313_A	0.610	0.76
40_N	44_A	0.610	0.76
44_A	47_G	0.609	0.76
221_E	471_S	0.608	0.76
283_M	287_N	0.608	0.76
26_Y	385_I	0.608	0.76
112_E	303_F	0.607	0.76
420_S	433_E	0.605	0.76
151_T	453_I	0.604	0.76
253_D	259_I	0.603	0.76
413_E	416_S	0.602	0.75
448_V	451_I	0.602	0.75
180_D	394_Y	0.602	0.75
244_V	299_F	0.600	0.75
45_Q	303_F	0.600	0.75
23_P	91_S	0.600	0.75
434_L	437_W	0.599	0.75
478_S	488_P	0.596	0.75
112_E	366_A	0.595	0.75
239_L	242_E	0.594	0.74
156_L	178_H	0.594	0.74
222_F	362_A	0.594	0.74
21_A	377_G	0.593	0.74
239_L	245_R	0.593	0.74
206_G	213_A	0.592	0.74
259_I	330_F	0.592	0.74
66_L	71_G	0.590	0.74
272_R	276_S	0.590	0.74
225_F	328_M	0.590	0.74
264_H	274_I	0.589	0.74
26_Y	384_I	0.589	0.74
280_H	325_A	0.589	0.74
102_N	108_C	0.589	0.74
489_H	492_V	0.589	0.74
205_D	457_E	0.589	0.74
47_G	245_R	0.588	0.74
65_T	78_V	0.586	0.73
47_G	226_H	0.586	0.73
190_G	223_T	0.586	0.73
280_H	283_M	0.585	0.73
242_E	246_G	0.584	0.73
195_H	325_A	0.584	0.73
440_T	443_F	0.582	0.73
406_V	410_E	0.581	0.73
251_L	260_M	0.581	0.73
431_L	472_A	0.580	0.73
163_I	346_P	0.580	0.73
449_K	452_T	0.579	0.73
349_Y	384_I	0.579	0.73
457_E	461_L	0.577	0.72
260_M	270_A	0.577	0.72
17_S	377_G	0.576	0.72
319_S	395_Q	0.575	0.72
153_A	166_M	0.575	0.72
496_G	499_I	0.575	0.72
131_L	135_Y	0.574	0.72
411_G	457_E	0.573	0.72
112_E	115_H	0.571	0.72
215_A	343_T	0.571	0.72
162_C	347_G	0.571	0.72
22_F	25_S	0.571	0.72
439_H	443_F	0.570	0.71
438_L	462_W	0.570	0.71
11_S	30_V	0.570	0.71
155_L	220_L	0.569	0.71
398_L	401_S	0.567	0.71
127_A	131_L	0.566	0.71
339_R	376_F	0.566	0.71
476_E	493_S	0.566	0.71
155_L	184_L	0.566	0.71
420_S	430_S	0.565	0.71
82_L	376_F	0.565	0.71
395_Q	432_I	0.564	0.71
35_S	148_E	0.564	0.71
296_I	299_F	0.564	0.71
20_A	97_F	0.562	0.70
168_K	172_G	0.560	0.70
110_G	302_R	0.559	0.70
17_S	95_R	0.558	0.70
211_Y	217_L	0.558	0.70
110_G	303_F	0.558	0.70
32_T	146_L	0.558	0.70
8_V	183_V	0.557	0.70
18_L	28_V	0.557	0.70
280_H	424_I	0.557	0.70
227_P	273_D	0.556	0.70
160_G	163_I	0.555	0.69
408_D	454_R	0.555	0.69
406_V	409_I	0.553	0.69
436_I	439_H	0.552	0.69
254_E	290_Y	0.552	0.69
329_H	364_R	0.552	0.69
417_K	438_L	0.552	0.69
252_V	256_G	0.550	0.69
274_I	277_R	0.549	0.69
330_F	333_G	0.549	0.69
377_G	384_I	0.549	0.69
30_V	36_V	0.549	0.69
409_I	420_S	0.548	0.68
375_V	379_R	0.548	0.68
340_W	382_E	0.547	0.68
466_K	469_T	0.544	0.68
253_D	262_E	0.543	0.68
137_L	141_N	0.543	0.68
228_T	242_E	0.543	0.68
224_Q	364_R	0.542	0.68
384_I	387_K	0.542	0.68
411_G	454_R	0.542	0.68
266_L	274_I	0.542	0.68
8_V	19_A	0.541	0.67
22_F	28_V	0.541	0.67
39_S	43_Y	0.540	0.67
298_D	319_S	0.540	0.67
109_L	367_S	0.537	0.67
305_T	309_I	0.537	0.67
256_G	321_K	0.537	0.67
297_S	318_H	0.536	0.67
156_L	163_I	0.534	0.66
31_I	150_E	0.534	0.66
414_L	461_L	0.533	0.66
284_A	485_T	0.533	0.66
33_K	461_L	0.533	0.66
230_L	233_N	0.532	0.66
326_P	330_F	0.530	0.66
253_D	268_D	0.530	0.66
182_V	347_G	0.530	0.66
55_D	117_Y	0.529	0.66
260_M	269_L	0.528	0.66
135_Y	139_R	0.528	0.66
38_N	41_S	0.528	0.66
327_G	330_F	0.528	0.66
494_W	499_I	0.527	0.65
303_F	310_C	0.527	0.65
413_E	440_T	0.527	0.65
472_A	478_S	0.527	0.65
162_C	179_A	0.525	0.65
42_V	134_D	0.525	0.65
26_Y	388_P	0.524	0.65
23_P	28_V	0.524	0.65
39_S	46_G	0.524	0.65
151_T	460_H	0.523	0.65
386_Q	391_N	0.522	0.65
341_G	376_F	0.522	0.65
329_H	332_M	0.522	0.65
288_R	323_P	0.521	0.65
299_F	306_I	0.520	0.64
259_I	267_G	0.519	0.64
100_D	125_G	0.519	0.64
59_E	400_T	0.517	0.64
407_P	458_L	0.516	0.64
41_S	44_A	0.513	0.63
47_G	239_L	0.513	0.63
276_S	424_I	0.512	0.63
62_L	83_H	0.511	0.63
79_A	82_L	0.510	0.63
68_A	271_P	0.510	0.63
209_L	213_A	0.509	0.63
272_R	363_N	0.508	0.63
162_C	348_L	0.508	0.63
474_L	498_Q	0.507	0.62
469_T	473_L	0.506	0.62
153_A	167_T	0.505	0.62
97_F	134_D	0.504	0.62
47_G	369_S	0.504	0.62
8_V	25_S	0.503	0.62
24_P	382_E	0.502	0.62
53_A	109_L	0.502	0.62
294_S	297_S	0.501	0.62
476_E	484_R	0.501	0.62
11_S	35_S	0.501	0.62
88_M	375_V	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bs2A	2	0.9925	100	0.274	Contact Map
2h88A	2	0.9887	100	0.279	Contact Map
1kf6A	1	0.9774	100	0.285	Contact Map
2wdqA	1	0.9774	100	0.294	Contact Map
1chuA	2	0.8475	100	0.321	Contact Map
2e5vA	1	0.8851	100	0.339	Contact Map
3gyxA	2	0.9492	100	0.362	Contact Map
1jnrA	2	0.9435	100	0.401	Contact Map
4c3xA	4	0.7006	100	0.571	Contact Map
4at0A	2	0.6911	100	0.627	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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