UVRB - BACSU - GREMLIN Contacts

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UVRB - UvrABC system protein B

UniProt:	P37954	Sequences: MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVSLRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDHVAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGSTPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYEIEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSMEIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAKALDFERAAELRDLLLELKAEG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	661 (649)
Sequences:	2701 (1155)
Seq/√Len:	45.3

ECOLI - UVRB
BACSU - UVRB
HALSA - UVRB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
6_E	83_N	5.340	1.00
49_V	336_V	4.974	1.00
271_L	286_L	4.316	1.00
40_A	43_T	4.259	1.00
561_E	565_N	3.887	1.00
25_V	55_E	3.527	1.00
359_Q	363_D	3.477	1.00
576_R	580_E	3.265	1.00
264_E	298_R	3.250	1.00
54_K	57_N	3.210	1.00
434_L	450_V	3.163	1.00
200_V	216_F	3.134	1.00
202_I	214_V	3.128	1.00
526_G	529_R	3.093	1.00
317_P	320_S	3.078	1.00
34_H	391_Y	3.077	1.00
270_Q	273_V	3.067	1.00
355_Q	359_Q	3.026	1.00
488_I	511_I	2.994	1.00
526_G	530_S	2.985	1.00
22_E	55_E	2.964	1.00
134_R	332_D	2.889	1.00
435_I	470_I	2.845	1.00
8_V	83_N	2.838	1.00
36_T	404_T	2.789	1.00
637_E	641_A	2.756	1.00
527_F	530_S	2.755	1.00
262_N	312_H	2.750	1.00
63_I	347_V	2.744	1.00
53_I	137_I	2.694	1.00
446_E	515_S	2.692	1.00
631_M	654_L	2.662	1.00
90_V	481_T	2.637	1.00
551_M	554_D	2.593	1.00
529_R	532_R	2.529	1.00
272_K	276_E	2.504	1.00
266_E	312_H	2.475	1.00
7_L	51_N	2.457	1.00
274_M	286_L	2.446	1.00
632_E	658_K	2.420	1.00
446_E	544_N	2.398	1.00
473_N	496_Y	2.371	1.00
267_L	271_L	2.358	1.00
28_I	390_V	2.349	1.00
287_E	291_R	2.334	1.00
275_H	287_E	2.323	1.00
441_R	546_E	2.318	1.00
214_V	221_I	2.316	1.00
62_V	77_F	2.312	1.00
572_E	576_R	2.309	1.00
418_L	575_E	2.299	1.00
575_E	579_E	2.272	1.00
558_K	562_I	2.260	1.00
51_N	54_K	2.237	1.00
489_R	493_L	2.225	1.00
321_T	385_H	2.198	1.00
27_G	32_K	2.198	1.00
542_A	587_T	2.193	1.00
527_F	562_I	2.184	1.00
549_V	552_Y	2.176	1.00
60_T	334_M	2.175	1.00
103_P	360_V	2.172	1.00
646_R	649_E	2.155	1.00
7_L	54_K	2.125	1.00
273_V	277_N	2.111	1.00
60_T	336_V	2.107	1.00
260_I	294_L	2.106	1.00
530_S	533_S	2.096	1.00
425_R	433_D	2.093	1.00
490_D	495_K	2.092	1.00
172_L	200_V	2.085	1.00
547_G	550_I	2.040	0.99
383_E	399_Y	2.039	0.99
529_R	533_S	2.028	0.99
545_A	549_V	2.022	0.99
528_L	532_R	2.018	0.99
536_Q	539_G	1.982	0.99
550_I	553_A	1.975	0.99
26_K	30_E	1.970	0.99
337_V	344_I	1.967	0.99
172_L	216_F	1.958	0.99
28_I	56_V	1.952	0.99
19_K	22_E	1.945	0.99
525_E	559_S	1.943	0.99
537_T	541_A	1.925	0.99
566_E	569_R	1.917	0.99
545_A	548_R	1.894	0.99
536_Q	541_A	1.893	0.99
425_R	437_E	1.874	0.99
441_R	446_E	1.868	0.99
173_L	200_V	1.864	0.99
441_R	515_S	1.854	0.99
568_K	572_E	1.845	0.99
19_K	23_K	1.845	0.99
558_K	561_E	1.841	0.99
440_A	443_E	1.840	0.99
528_L	533_S	1.836	0.99
560_M	564_I	1.831	0.99
653_L	656_E	1.816	0.99
13_P	21_I	1.805	0.99
271_L	287_E	1.800	0.99
634_E	646_R	1.799	0.99
526_G	532_R	1.798	0.99
352_N	356_A	1.797	0.99
264_E	291_R	1.794	0.98
280_L	284_Q	1.790	0.98
223_R	237_D	1.790	0.98
526_G	533_S	1.789	0.98
628_V	657_L	1.782	0.98
535_I	563_A	1.768	0.98
187_D	456_K	1.768	0.98
14_Q	577_F	1.752	0.98
586_K	589_N	1.743	0.98
437_E	440_A	1.724	0.98
422_I	564_I	1.723	0.98
527_F	533_S	1.711	0.98
22_E	26_K	1.695	0.98
266_E	370_S	1.690	0.98
527_F	532_R	1.686	0.98
29_Q	55_E	1.685	0.98
355_Q	372_L	1.680	0.98
434_L	518_A	1.680	0.98
638_A	650_L	1.668	0.98
211_C	227_V	1.656	0.97
87_E	125_S	1.651	0.97
533_S	536_Q	1.646	0.97
545_A	550_I	1.641	0.97
34_H	403_H	1.638	0.97
383_E	403_H	1.636	0.97
335_I	389_I	1.634	0.97
153_E	252_R	1.630	0.97
533_S	537_T	1.624	0.97
47_F	51_N	1.611	0.97
435_I	468_I	1.605	0.97
554_D	557_T	1.604	0.97
643_D	646_R	1.584	0.97
32_K	406_E	1.581	0.97
550_I	554_D	1.572	0.96
534_L	539_G	1.561	0.96
344_I	348_R	1.560	0.96
421_L	546_E	1.552	0.96
530_S	534_L	1.542	0.96
533_S	539_G	1.527	0.96
534_L	537_T	1.515	0.96
546_E	549_V	1.514	0.96
23_K	406_E	1.510	0.96
25_V	29_Q	1.500	0.95
161_L	221_I	1.499	0.95
262_N	266_E	1.494	0.95
24_L	27_G	1.488	0.95
423_D	546_E	1.487	0.95
444_R	544_N	1.485	0.95
311_R	373_D	1.471	0.95
527_F	534_L	1.471	0.95
49_V	390_V	1.470	0.95
260_I	298_R	1.467	0.95
270_Q	274_M	1.463	0.95
362_V	372_L	1.462	0.95
465_L	500_V	1.459	0.95
159_V	179_I	1.454	0.95
36_T	391_Y	1.454	0.95
58_K	388_N	1.451	0.94
470_I	498_V	1.448	0.94
257_E	298_R	1.441	0.94
442_I	471_K	1.437	0.94
533_S	541_A	1.436	0.94
548_R	551_M	1.433	0.94
212_V	241_V	1.427	0.94
256_M	297_M	1.409	0.94
549_V	553_A	1.404	0.93
329_F	333_F	1.401	0.93
529_R	534_L	1.400	0.93
537_T	545_A	1.397	0.93
188_F	211_C	1.397	0.93
159_V	172_L	1.391	0.93
326_L	335_I	1.390	0.93
27_G	35_Q	1.390	0.93
536_Q	545_A	1.386	0.93
162_R	165_M	1.384	0.93
386_M	389_I	1.381	0.93
65_H	343_T	1.380	0.93
496_Y	499_L	1.374	0.93
539_G	545_A	1.373	0.93
627_V	630_Q	1.367	0.93
634_E	650_L	1.362	0.92
552_Y	555_K	1.362	0.92
127_T	248_H	1.354	0.92
442_I	470_I	1.351	0.92
528_L	534_L	1.347	0.92
359_Q	372_L	1.346	0.92
541_A	545_A	1.343	0.92
421_L	575_E	1.338	0.92
547_G	551_M	1.335	0.92
534_L	541_A	1.333	0.92
273_V	286_L	1.330	0.91
24_L	390_V	1.329	0.91
52_L	336_V	1.324	0.91
85_A	133_R	1.323	0.91
537_T	542_A	1.316	0.91
632_E	636_K	1.316	0.91
572_E	580_E	1.315	0.91
530_S	536_Q	1.313	0.91
25_V	56_V	1.312	0.91
576_R	579_E	1.307	0.91
6_E	54_K	1.302	0.91
536_Q	542_A	1.296	0.90
530_S	537_T	1.295	0.90
279_K	282_E	1.295	0.90
548_R	552_Y	1.293	0.90
441_R	445_N	1.292	0.90
253_A	257_E	1.289	0.90
538_I	541_A	1.288	0.90
532_R	537_T	1.286	0.90
532_R	536_Q	1.282	0.90
447_R	494_G	1.280	0.90
281_L	286_L	1.273	0.90
471_K	495_K	1.273	0.90
268_E	272_K	1.272	0.90
351_F	378_R	1.265	0.89
336_V	390_V	1.264	0.89
546_E	550_I	1.260	0.89
440_A	444_R	1.259	0.89
526_G	534_L	1.258	0.89
564_I	568_K	1.256	0.89
398_P	402_E	1.251	0.89
624_R	654_L	1.247	0.89
49_V	392_V	1.246	0.89
539_G	542_A	1.240	0.88
62_V	139_I	1.237	0.88
58_K	134_R	1.236	0.88
182_A	192_T	1.233	0.88
530_S	539_G	1.229	0.88
175_K	178_D	1.222	0.88
532_R	539_G	1.216	0.87
630_Q	634_E	1.213	0.87
271_L	275_H	1.211	0.87
125_S	129_A	1.202	0.87
161_L	172_L	1.200	0.87
173_L	195_V	1.198	0.86
25_V	52_L	1.195	0.86
167_I	172_L	1.195	0.86
620_T	623_E	1.194	0.86
261_Q	265_K	1.194	0.86
545_A	551_M	1.190	0.86
58_K	332_D	1.185	0.86
283_A	287_E	1.182	0.86
81_F	137_I	1.181	0.86
337_V	389_I	1.181	0.86
271_L	274_M	1.176	0.85
529_R	536_Q	1.176	0.85
349_G	378_R	1.164	0.85
173_L	177_V	1.163	0.85
269_E	273_V	1.148	0.84
335_I	386_M	1.146	0.84
529_R	537_T	1.144	0.84
528_L	536_Q	1.136	0.83
344_I	379_F	1.133	0.83
79_E	593_R	1.132	0.83
433_D	550_I	1.130	0.83
527_F	536_Q	1.129	0.83
215_E	223_R	1.128	0.83
311_R	318_P	1.125	0.83
451_T	534_L	1.120	0.82
528_L	537_T	1.117	0.82
23_K	408_V	1.116	0.82
29_Q	56_V	1.115	0.82
411_I	573_Q	1.115	0.82
185_D	196_R	1.114	0.82
565_N	568_K	1.109	0.82
529_R	539_G	1.105	0.82
226_E	236_G	1.099	0.81
485_I	595_V	1.098	0.81
421_L	568_K	1.095	0.81
629_E	632_E	1.095	0.81
264_E	294_L	1.093	0.81
258_K	262_N	1.093	0.81
547_G	552_Y	1.091	0.81
539_G	544_N	1.090	0.81
530_S	541_A	1.089	0.81
527_F	537_T	1.088	0.81
266_E	269_E	1.085	0.80
56_V	60_T	1.083	0.80
628_V	654_L	1.083	0.80
215_E	225_R	1.082	0.80
401_I	407_M	1.076	0.80
58_K	336_V	1.073	0.80
404_T	407_M	1.067	0.79
532_R	541_A	1.064	0.79
528_L	539_G	1.061	0.79
265_K	268_E	1.060	0.79
541_A	547_G	1.055	0.79
450_V	520_L	1.053	0.78
551_M	555_K	1.050	0.78
62_V	137_I	1.050	0.78
153_E	255_K	1.047	0.78
549_V	554_D	1.043	0.78
130_L	136_V	1.041	0.78
105_T	304_S	1.040	0.78
493_L	592_I	1.039	0.77
424_V	564_I	1.039	0.77
163_T	239_D	1.038	0.77
533_S	538_I	1.037	0.77
449_L	511_I	1.035	0.77
537_T	544_N	1.034	0.77
593_R	596_I	1.031	0.77
58_K	334_M	1.031	0.77
195_V	200_V	1.023	0.76
118_E	122_L	1.020	0.76
536_Q	544_N	1.019	0.76
360_V	372_L	1.019	0.76
436_G	439_Q	1.017	0.76
526_G	537_T	1.015	0.76
552_Y	557_T	1.015	0.76
579_E	582_G	1.013	0.76
533_S	545_A	1.012	0.76
132_E	244_F	1.012	0.76
537_T	547_G	1.012	0.76
527_F	539_G	1.009	0.75
344_I	347_V	1.007	0.75
526_G	536_Q	1.006	0.75
545_A	552_Y	1.002	0.75
188_F	203_F	1.002	0.75
401_I	404_T	1.002	0.75
32_K	405_D	0.999	0.75
264_E	268_E	0.999	0.75
534_L	538_I	0.998	0.75
36_T	403_H	0.997	0.74
529_R	541_A	0.996	0.74
4_R	57_N	0.996	0.74
64_A	73_L	0.992	0.74
347_V	386_M	0.991	0.74
625_Q	629_E	0.991	0.74
162_R	240_H	0.989	0.74
49_V	52_L	0.987	0.74
312_H	370_S	0.986	0.74
314_T	323_Y	0.983	0.73
397_G	404_T	0.979	0.73
536_Q	547_G	0.979	0.73
330_P	387_H	0.978	0.73
211_C	229_A	0.976	0.73
58_K	387_H	0.975	0.73
471_K	494_G	0.975	0.73
12_Q	51_N	0.974	0.73
19_K	573_Q	0.969	0.72
539_G	547_G	0.964	0.72
637_E	640_K	0.963	0.72
157_M	252_R	0.960	0.72
120_D	190_R	0.955	0.71
262_N	315_L	0.953	0.71
352_N	378_R	0.950	0.71
217_F	222_E	0.949	0.71
473_N	490_D	0.946	0.70
475_L	479_I	0.945	0.70
63_I	337_V	0.941	0.70
53_I	62_V	0.941	0.70
189_Q	192_T	0.936	0.70
51_N	55_E	0.934	0.69
265_K	269_E	0.934	0.69
649_E	653_L	0.932	0.69
63_I	335_I	0.931	0.69
262_N	265_K	0.929	0.69
255_K	258_K	0.928	0.69
161_L	224_I	0.927	0.69
348_R	398_P	0.927	0.69
125_S	138_I	0.924	0.69
424_V	560_M	0.921	0.68
273_V	276_E	0.919	0.68
101_Y	106_D	0.919	0.68
546_E	551_M	0.916	0.68
27_G	390_V	0.914	0.68
326_L	382_F	0.914	0.68
541_A	544_N	0.912	0.68
124_H	154_Y	0.911	0.68
161_L	214_V	0.911	0.68
526_G	539_G	0.909	0.67
538_I	545_A	0.907	0.67
226_E	238_R	0.906	0.67
399_Y	403_H	0.906	0.67
438_I	450_V	0.906	0.67
7_L	57_N	0.900	0.67
490_D	496_Y	0.897	0.66
631_M	650_L	0.897	0.66
537_T	548_R	0.895	0.66
153_E	156_E	0.894	0.66
446_E	546_E	0.894	0.66
536_Q	548_R	0.891	0.66
528_L	541_A	0.890	0.66
215_E	222_E	0.888	0.66
525_E	557_T	0.887	0.65
74_Y	78_K	0.885	0.65
281_L	288_Q	0.885	0.65
126_A	138_I	0.883	0.65
527_F	541_A	0.882	0.65
28_I	388_N	0.879	0.65
27_G	406_E	0.879	0.65
310_S	354_D	0.878	0.65
465_L	468_I	0.877	0.65
435_I	465_L	0.873	0.64
65_H	342_V	0.873	0.64
256_M	313_L	0.866	0.64
441_R	448_V	0.866	0.64
534_L	545_A	0.865	0.63
277_N	363_D	0.863	0.63
110_E	288_Q	0.862	0.63
271_L	283_A	0.859	0.63
655_L	658_K	0.859	0.63
638_A	646_R	0.855	0.63
212_V	243_I	0.854	0.62
445_N	448_V	0.851	0.62
398_P	528_L	0.849	0.62
266_E	313_L	0.849	0.62
216_F	221_I	0.843	0.61
272_K	275_H	0.843	0.61
455_K	477_S	0.842	0.61
349_G	352_N	0.840	0.61
422_I	535_I	0.838	0.61
546_E	552_Y	0.837	0.61
655_L	659_A	0.837	0.61
486_E	489_R	0.836	0.61
28_I	334_M	0.834	0.61
261_Q	264_E	0.833	0.61
619_M	623_E	0.833	0.61
275_H	278_G	0.833	0.61
515_S	546_E	0.833	0.61
442_I	498_V	0.831	0.60
539_G	548_R	0.831	0.60
124_H	206_S	0.830	0.60
23_K	26_K	0.830	0.60
530_S	545_A	0.830	0.60
65_H	344_I	0.829	0.60
613_A	618_K	0.827	0.60
168_E	174_R	0.825	0.60
217_F	220_E	0.824	0.60
568_K	575_E	0.824	0.60
435_I	439_Q	0.824	0.60
259_A	263_I	0.820	0.59
326_L	333_F	0.818	0.59
49_V	62_V	0.817	0.59
275_H	283_A	0.817	0.59
492_R	513_E	0.816	0.59
541_A	549_V	0.814	0.59
163_T	237_D	0.810	0.58
150_S	314_T	0.809	0.58
553_A	557_T	0.808	0.58
202_I	243_I	0.802	0.58
210_H	235_L	0.801	0.58
167_I	221_I	0.801	0.58
627_V	653_L	0.799	0.57
120_D	126_A	0.798	0.57
528_L	562_I	0.795	0.57
526_G	541_A	0.793	0.57
348_R	352_N	0.791	0.57
210_H	226_E	0.789	0.56
422_I	563_A	0.786	0.56
335_I	387_H	0.784	0.56
258_K	312_H	0.784	0.56
427_I	431_I	0.784	0.56
27_G	56_V	0.784	0.56
134_R	388_N	0.784	0.56
438_I	448_V	0.783	0.56
530_S	538_I	0.783	0.56
379_F	399_Y	0.782	0.56
157_M	250_V	0.781	0.56
259_A	312_H	0.779	0.55
337_V	347_V	0.777	0.55
479_I	487_I	0.776	0.55
63_I	343_T	0.773	0.55
60_T	387_H	0.773	0.55
541_A	548_R	0.772	0.55
551_M	557_T	0.771	0.55
656_E	659_A	0.765	0.54
77_F	336_V	0.765	0.54
212_V	226_E	0.762	0.54
482_L	485_I	0.762	0.54
603_E	608_Y	0.759	0.53
120_D	138_I	0.759	0.53
198_D	218_G	0.758	0.53
167_I	175_K	0.757	0.53
452_T	520_L	0.757	0.53
455_K	478_E	0.757	0.53
113_A	274_M	0.755	0.53
537_T	549_V	0.754	0.53
161_L	243_I	0.753	0.53
434_L	520_L	0.753	0.53
28_I	58_K	0.753	0.53
418_L	423_D	0.751	0.53
458_S	471_K	0.751	0.53
456_K	460_D	0.748	0.52
349_G	397_G	0.747	0.52
128_S	132_E	0.747	0.52
5_F	60_T	0.747	0.52
129_A	478_E	0.746	0.52
383_E	391_Y	0.745	0.52
172_L	214_V	0.742	0.52
270_Q	369_P	0.741	0.52
164_E	220_E	0.739	0.52
347_V	389_I	0.738	0.51
438_I	498_V	0.738	0.51
464_Y	468_I	0.737	0.51
260_I	297_M	0.735	0.51
349_G	398_P	0.734	0.51
203_F	211_C	0.730	0.51
412_I	419_D	0.729	0.51
169_R	200_V	0.729	0.51
537_T	550_I	0.729	0.51
138_I	328_Y	0.729	0.51
63_I	389_I	0.728	0.50
529_R	538_I	0.727	0.50
176_L	214_V	0.727	0.50
294_L	298_R	0.725	0.50
54_K	83_N	0.725	0.50
533_S	542_A	0.725	0.50
541_A	546_E	0.724	0.50
12_Q	47_F	0.724	0.50
85_A	136_V	0.723	0.50
75_S	596_I	0.722	0.50
533_S	547_G	0.721	0.50
169_R	173_L	0.721	0.50
335_I	347_V	0.720	0.50
648_A	652_D	0.720	0.50
87_E	129_A	0.719	0.50
79_E	590_K	0.717	0.49
437_E	548_R	0.716	0.49
425_R	550_I	0.716	0.49
159_V	175_K	0.715	0.49
536_Q	549_V	0.714	0.49
63_I	382_F	0.713	0.49
128_S	206_S	0.712	0.49
64_A	124_H	0.711	0.49
448_V	451_T	0.711	0.49
24_L	35_Q	0.709	0.49
65_H	131_F	0.708	0.49
247_S	302_F	0.707	0.48
234_I	237_D	0.706	0.48
112_D	304_S	0.705	0.48
541_A	587_T	0.704	0.48
35_Q	56_V	0.704	0.48
579_E	586_K	0.703	0.48
212_V	224_I	0.703	0.48
539_G	549_V	0.702	0.48
462_T	472_V	0.701	0.48
271_L	281_L	0.700	0.48
7_L	12_Q	0.700	0.48
189_Q	456_K	0.699	0.48
466_K	472_V	0.698	0.48
344_I	389_I	0.696	0.47
515_S	544_N	0.696	0.47
11_Y	51_N	0.694	0.47
63_I	144_C	0.693	0.47
274_M	277_N	0.693	0.47
134_R	387_H	0.692	0.47
472_V	500_V	0.691	0.47
356_A	360_V	0.690	0.47
36_T	405_D	0.689	0.47
228_D	233_E	0.688	0.47
169_R	195_V	0.688	0.47
150_S	250_V	0.688	0.47
424_V	561_E	0.687	0.46
632_E	654_L	0.687	0.46
535_I	567_T	0.683	0.46
75_S	78_K	0.682	0.46
36_T	383_E	0.681	0.46
527_F	538_I	0.681	0.46
148_L	302_F	0.680	0.46
226_E	241_V	0.680	0.46
218_G	222_E	0.679	0.46
10_K	591_E	0.678	0.46
270_Q	363_D	0.678	0.46
412_I	429_G	0.677	0.46
633_H	637_E	0.677	0.46
262_N	318_P	0.676	0.45
138_I	584_T	0.676	0.45
272_K	576_R	0.676	0.45
238_R	241_V	0.675	0.45
289_R	362_V	0.675	0.45
7_L	25_V	0.675	0.45
268_E	287_E	0.675	0.45
638_A	643_D	0.675	0.45
152_E	156_E	0.675	0.45
26_K	29_Q	0.673	0.45
144_C	326_L	0.673	0.45
536_Q	550_I	0.672	0.45
473_N	499_L	0.671	0.45
274_M	279_K	0.671	0.45
391_Y	403_H	0.671	0.45
624_R	627_V	0.669	0.45
563_A	569_R	0.667	0.45
154_Y	324_T	0.666	0.44
316_R	447_R	0.666	0.44
445_N	589_N	0.664	0.44
257_E	261_Q	0.664	0.44
458_S	496_Y	0.663	0.44
246_A	329_F	0.662	0.44
321_T	324_T	0.660	0.44
159_V	200_V	0.660	0.44
439_Q	443_E	0.660	0.44
124_H	247_S	0.659	0.44
160_S	240_H	0.656	0.43
646_R	650_L	0.654	0.43
479_I	483_E	0.654	0.43
352_N	380_E	0.654	0.43
551_M	564_I	0.652	0.43
24_L	48_T	0.652	0.43
626_K	631_M	0.652	0.43
541_A	550_I	0.651	0.43
61_L	144_C	0.650	0.43
438_I	442_I	0.649	0.43
538_I	547_G	0.649	0.43
438_I	445_N	0.649	0.43
297_M	306_I	0.648	0.43
10_K	589_N	0.646	0.43
290_T	294_L	0.646	0.43
331_D	387_H	0.645	0.42
539_G	550_I	0.645	0.42
11_Y	590_K	0.645	0.42
273_V	279_K	0.645	0.42
138_I	240_H	0.645	0.42
85_A	129_A	0.642	0.42
9_S	12_Q	0.642	0.42
65_H	73_L	0.641	0.42
62_V	336_V	0.640	0.42
480_K	483_E	0.640	0.42
122_L	483_E	0.638	0.42
200_V	224_I	0.637	0.42
58_K	330_P	0.637	0.42
416_G	583_I	0.636	0.42
598_A	601_A	0.635	0.41
150_S	255_K	0.635	0.41
207_R	226_E	0.635	0.41
256_M	260_I	0.634	0.41
52_L	103_P	0.634	0.41
532_R	545_A	0.633	0.41
268_E	291_R	0.631	0.41
528_L	538_I	0.631	0.41
451_T	509_L	0.630	0.41
61_L	326_L	0.629	0.41
240_H	431_I	0.629	0.41
36_T	401_I	0.627	0.41
532_R	538_I	0.627	0.41
534_L	544_N	0.626	0.41
349_G	559_S	0.626	0.41
124_H	248_H	0.626	0.41
77_F	139_I	0.626	0.41
172_L	175_K	0.626	0.41
569_R	590_K	0.626	0.41
19_K	411_I	0.626	0.41
362_V	371_A	0.626	0.41
119_I	299_E	0.626	0.41
572_E	579_E	0.625	0.41
547_G	553_A	0.625	0.41
194_R	201_E	0.625	0.41
442_I	448_V	0.624	0.40
19_K	408_V	0.623	0.40
590_K	593_R	0.623	0.40
25_V	28_I	0.622	0.40
542_A	545_A	0.622	0.40
64_A	247_S	0.621	0.40
124_H	205_A	0.621	0.40
532_R	562_I	0.621	0.40
489_R	594_D	0.621	0.40
344_I	399_Y	0.621	0.40
174_R	178_D	0.620	0.40
177_V	193_F	0.619	0.40
537_T	546_E	0.619	0.40
201_E	227_V	0.619	0.40
11_Y	104_Q	0.618	0.40
12_Q	54_K	0.618	0.40
533_S	548_R	0.617	0.40
529_R	545_A	0.617	0.40
74_Y	124_H	0.616	0.40
418_L	421_L	0.616	0.40
122_L	242_A	0.616	0.40
113_A	302_F	0.615	0.40
563_A	566_E	0.615	0.40
247_S	250_V	0.615	0.40
10_K	398_P	0.614	0.39
452_T	458_S	0.614	0.39
606_A	658_K	0.613	0.39
327_D	385_H	0.612	0.39
22_E	576_R	0.611	0.39
224_I	238_R	0.611	0.39
279_K	286_L	0.610	0.39
545_A	553_A	0.610	0.39
351_F	356_A	0.610	0.39
433_D	437_E	0.610	0.39
124_H	128_S	0.609	0.39
124_H	131_F	0.609	0.39
463_D	466_K	0.608	0.39
65_H	528_L	0.607	0.39
148_L	151_P	0.606	0.39
55_E	60_T	0.606	0.39
538_I	544_N	0.604	0.39
584_T	591_E	0.604	0.39
360_V	478_E	0.604	0.39
73_L	77_F	0.604	0.39
572_E	575_E	0.604	0.39
634_E	638_A	0.603	0.38
618_K	621_K	0.603	0.38
95_Y	110_E	0.602	0.38
120_D	124_H	0.602	0.38
167_I	216_F	0.602	0.38
542_A	586_K	0.602	0.38
475_L	488_I	0.601	0.38
544_N	547_G	0.601	0.38
140_A	212_V	0.600	0.38
148_L	248_H	0.599	0.38
601_A	608_Y	0.599	0.38
131_F	328_Y	0.598	0.38
229_A	456_K	0.598	0.38
225_R	237_D	0.598	0.38
29_Q	58_K	0.597	0.38
409_E	569_R	0.596	0.38
127_T	149_G	0.596	0.38
251_T	432_D	0.596	0.38
15_G	18_P	0.595	0.38
349_G	482_L	0.595	0.38
249_F	412_I	0.593	0.38
49_V	77_F	0.593	0.38
447_R	471_K	0.593	0.38
110_E	115_I	0.592	0.37
233_E	429_G	0.592	0.37
489_R	502_I	0.592	0.37
425_R	548_R	0.592	0.37
450_V	518_A	0.591	0.37
97_Q	112_D	0.590	0.37
418_L	542_A	0.590	0.37
171_E	175_K	0.589	0.37
386_M	391_Y	0.589	0.37
438_I	470_I	0.587	0.37
149_G	248_H	0.586	0.37
236_G	598_A	0.586	0.37
29_Q	32_K	0.586	0.37
244_F	328_Y	0.585	0.37
10_K	51_N	0.584	0.37
450_V	582_G	0.584	0.37
11_Y	65_H	0.584	0.37
442_I	496_Y	0.584	0.37
321_T	377_L	0.584	0.37
251_T	313_L	0.583	0.37
445_N	515_S	0.583	0.37
444_R	515_S	0.582	0.37
158_V	242_A	0.581	0.36
380_E	383_E	0.580	0.36
77_F	137_I	0.580	0.36
63_I	344_I	0.579	0.36
33_K	386_M	0.579	0.36
438_I	465_L	0.579	0.36
102_V	205_A	0.578	0.36
63_I	225_R	0.578	0.36
473_N	479_I	0.578	0.36
152_E	158_V	0.578	0.36
75_S	593_R	0.578	0.36
440_A	546_E	0.578	0.36
29_Q	60_T	0.577	0.36
93_Y	143_S	0.577	0.36
397_G	401_I	0.577	0.36
131_F	138_I	0.577	0.36
537_T	551_M	0.576	0.36
397_G	528_L	0.576	0.36
59_P	330_P	0.576	0.36
536_Q	546_E	0.575	0.36
65_H	398_P	0.575	0.36
38_L	52_L	0.575	0.36
266_E	270_Q	0.575	0.36
548_R	553_A	0.572	0.36
326_L	329_F	0.572	0.36
278_G	284_Q	0.572	0.36
206_S	227_V	0.571	0.36
337_V	399_Y	0.571	0.36
527_F	545_A	0.570	0.35
179_I	250_V	0.570	0.35
445_N	582_G	0.570	0.35
584_T	587_T	0.570	0.35
238_R	598_A	0.570	0.35
50_S	71_G	0.570	0.35
184_N	284_Q	0.569	0.35
351_F	359_Q	0.569	0.35
249_F	472_V	0.569	0.35
127_T	148_L	0.568	0.35
279_K	363_D	0.568	0.35
569_R	573_Q	0.568	0.35
4_R	54_K	0.568	0.35
271_L	312_H	0.568	0.35
134_R	330_P	0.567	0.35
255_K	315_L	0.566	0.35
184_N	230_L	0.566	0.35
566_E	590_K	0.566	0.35
621_K	625_Q	0.565	0.35
30_E	33_K	0.565	0.35
288_Q	304_S	0.565	0.35
398_P	527_F	0.564	0.35
536_Q	551_M	0.564	0.35
217_F	457_M	0.564	0.35
74_Y	511_I	0.564	0.35
194_R	232_G	0.564	0.35
455_K	496_Y	0.563	0.35
490_D	493_L	0.562	0.35
113_A	372_L	0.562	0.35
57_N	60_T	0.562	0.35
449_L	509_L	0.561	0.35
64_A	478_E	0.561	0.35
152_E	314_T	0.560	0.35
559_S	562_I	0.560	0.35
489_R	592_I	0.560	0.35
267_L	274_M	0.559	0.34
251_T	256_M	0.558	0.34
478_E	499_L	0.558	0.34
118_E	488_I	0.557	0.34
63_I	140_A	0.557	0.34
530_S	547_G	0.557	0.34
49_V	137_I	0.557	0.34
526_G	545_A	0.556	0.34
7_L	55_E	0.556	0.34
163_T	166_E	0.555	0.34
314_T	320_S	0.555	0.34
40_A	49_V	0.555	0.34
475_L	481_T	0.554	0.34
164_E	435_I	0.554	0.34
448_V	499_L	0.554	0.34
442_I	500_V	0.554	0.34
61_L	329_F	0.553	0.34
326_L	377_L	0.553	0.34
83_N	444_R	0.552	0.34
128_S	158_V	0.551	0.34
304_S	360_V	0.551	0.34
429_G	436_G	0.550	0.34
332_D	387_H	0.549	0.34
203_F	207_R	0.549	0.34
573_Q	576_R	0.549	0.34
297_M	304_S	0.549	0.34
171_E	174_R	0.549	0.34
136_V	468_I	0.548	0.34
131_F	482_L	0.548	0.34
439_Q	470_I	0.547	0.33
342_V	345_P	0.546	0.33
566_E	570_R	0.546	0.33
637_E	643_D	0.545	0.33
120_D	573_Q	0.545	0.33
422_I	560_M	0.544	0.33
157_M	179_I	0.544	0.33
324_T	385_H	0.543	0.33
458_S	475_L	0.543	0.33
11_Y	80_F	0.543	0.33
22_E	29_Q	0.543	0.33
92_Y	143_S	0.542	0.33
8_V	57_N	0.542	0.33
466_K	486_E	0.541	0.33
530_S	542_A	0.541	0.33
107_T	119_I	0.539	0.33
49_V	56_V	0.538	0.33
53_I	60_T	0.537	0.33
360_V	364_H	0.537	0.33
46_T	49_V	0.537	0.33
140_A	154_Y	0.537	0.33
103_P	364_H	0.536	0.32
478_E	500_V	0.535	0.32
258_K	315_L	0.535	0.32
533_S	544_N	0.534	0.32
457_M	461_L	0.534	0.32
75_S	595_V	0.533	0.32
360_V	378_R	0.532	0.32
131_F	274_M	0.532	0.32
619_M	627_V	0.531	0.32
528_L	547_G	0.531	0.32
56_V	390_V	0.531	0.32
588_I	591_E	0.531	0.32
643_D	654_L	0.530	0.32
93_Y	127_T	0.529	0.32
471_K	496_Y	0.529	0.32
11_Y	629_E	0.529	0.32
487_I	496_Y	0.529	0.32
141_S	378_R	0.528	0.32
108_F	360_V	0.527	0.32
528_L	545_A	0.527	0.32
205_A	229_A	0.527	0.32
85_A	150_S	0.526	0.32
148_L	155_R	0.526	0.32
108_F	654_L	0.526	0.32
77_F	333_F	0.526	0.32
534_L	547_G	0.526	0.32
224_I	243_I	0.525	0.32
143_S	149_G	0.525	0.32
616_L	624_R	0.525	0.32
32_K	408_V	0.524	0.31
434_L	438_I	0.524	0.31
441_R	444_R	0.524	0.31
333_F	387_H	0.523	0.31
547_G	554_D	0.522	0.31
437_E	546_E	0.522	0.31
267_L	291_R	0.522	0.31
436_G	440_A	0.522	0.31
14_Q	18_P	0.521	0.31
108_F	300_M	0.521	0.31
242_A	251_T	0.521	0.31
539_G	546_E	0.520	0.31
252_R	313_L	0.520	0.31
154_Y	370_S	0.520	0.31
120_D	128_S	0.520	0.31
106_D	288_Q	0.519	0.31
247_S	502_I	0.519	0.31
7_L	47_F	0.519	0.31
71_G	480_K	0.519	0.31
538_I	551_M	0.518	0.31
572_E	658_K	0.518	0.31
129_A	604_D	0.518	0.31
517_V	534_L	0.518	0.31
417_L	502_I	0.517	0.31
128_S	155_R	0.517	0.31
108_F	427_I	0.517	0.31
274_M	284_Q	0.517	0.31
141_S	144_C	0.516	0.31
262_N	297_M	0.516	0.31
65_H	130_L	0.516	0.31
418_L	563_A	0.516	0.31
121_K	179_I	0.515	0.31
179_I	599_T	0.515	0.31
650_L	654_L	0.514	0.31
203_F	481_T	0.513	0.31
431_I	465_L	0.512	0.30
249_F	302_F	0.512	0.30
203_F	214_V	0.511	0.30
246_A	304_S	0.511	0.30
615_K	619_M	0.511	0.30
113_A	280_L	0.511	0.30
382_F	514_V	0.511	0.30
382_F	452_T	0.510	0.30
149_G	296_M	0.509	0.30
634_E	637_E	0.509	0.30
623_E	626_K	0.509	0.30
155_R	158_V	0.509	0.30
377_L	385_H	0.508	0.30
172_L	202_I	0.508	0.30
274_M	318_P	0.508	0.30
34_H	129_A	0.507	0.30
62_V	456_K	0.507	0.30
185_D	230_L	0.506	0.30
102_V	360_V	0.506	0.30
442_I	497_D	0.506	0.30
534_L	542_A	0.505	0.30
595_V	598_A	0.505	0.30
43_T	49_V	0.505	0.30
198_D	217_F	0.504	0.30
290_T	370_S	0.504	0.30
336_V	511_I	0.504	0.30
638_A	641_A	0.504	0.30
204_P	328_Y	0.504	0.30
27_G	288_Q	0.504	0.30
290_T	312_H	0.504	0.30
14_Q	586_K	0.504	0.30
559_S	644_F	0.504	0.30
626_K	633_H	0.504	0.30
151_P	371_A	0.503	0.30
36_T	150_S	0.503	0.30
545_A	587_T	0.503	0.30
190_R	247_S	0.503	0.30
19_K	398_P	0.503	0.30
181_Y	517_V	0.503	0.30
225_R	234_I	0.503	0.30
80_F	124_H	0.503	0.30
160_S	242_A	0.502	0.30
435_I	500_V	0.502	0.30
14_Q	108_F	0.501	0.30
536_Q	552_Y	0.501	0.30
349_G	360_V	0.501	0.30
532_R	547_G	0.501	0.30
80_F	251_T	0.501	0.30
25_V	57_N	0.500	0.29
119_I	343_T	0.500	0.29
11_Y	62_V	0.500	0.29
43_T	352_N	0.500	0.29
643_D	658_K	0.500	0.29
52_L	390_V	0.500	0.29
542_A	547_G	0.500	0.29
625_Q	658_K	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2d7dA	2	0.941	100	0.497	Contact Map
1c4oA	1	0.7413	100	0.506	Contact Map
2eyqA	1	0.8427	100	0.723	Contact Map
3hjhA	1	0.6505	100	0.736	Contact Map
4gl2A	1	0.7474	100	0.887	Contact Map
4a4zA	1	0.5991	100	0.893	Contact Map
4nl4H	1	0.6142	100	0.901	Contact Map
1gm5A	1	0.5371	100	0.902	Contact Map
3fhoA	2	0.4357	100	0.904	Contact Map
2ocaA	1	0.5265	100	0.905	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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