GREMLIN Database
LEPA - Elongation factor 4
UniProt: P37949 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 612 (523)
Sequences: 6074 (2523)
Seq/√Len: 110.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
149_E152_R4.7991.00
202_K224_E4.3131.00
455_D484_I4.0561.00
260_L266_G4.0201.00
228_K259_E3.9741.00
171_A182_I3.7821.00
231_Q286_S3.5531.00
455_D487_K3.4741.00
508_F511_H3.3741.00
413_Y487_K3.3521.00
246_E256_P3.1871.00
185_Q189_K3.1811.00
169_V185_Q3.1721.00
184_E188_E3.0401.00
507_S510_V3.0041.00
74_K80_E2.9991.00
408_R488_P2.9571.00
415_K484_I2.9231.00
226_T259_E2.8261.00
196_D199_A2.8141.00
558_K561_L2.7901.00
420_V428_V2.7621.00
383_D410_E2.5851.00
441_D453_I2.5841.00
490_K512_R2.5461.00
232_K241_E2.5421.00
387_T410_E2.5331.00
415_K453_I2.5301.00
249_V252_P2.5091.00
154_R168_A2.5051.00
440_I455_D2.4541.00
33_R36_E2.4501.00
72_K80_E2.4471.00
469_L477_A2.4191.00
42_T45_E2.4161.00
431_L465_F2.4081.00
473_T477_A2.4061.00
416_A479_F2.3881.00
143_I177_I2.3031.00
139_V171_A2.2081.00
248_G252_P2.1751.00
432_C437_G2.1581.00
17_F83_F2.1561.00
431_L472_S2.1361.00
385_Y408_R2.1111.00
41_I50_L2.0981.00
199_A224_E2.0881.00
81_Y187_V2.0861.00
226_T261_T2.0071.00
229_P258_N1.9891.00
222_V260_L1.9891.00
154_R170_L1.9631.00
248_G251_T1.9591.00
366_E372_D1.9511.00
234_K241_E1.9371.00
438_N487_K1.9291.00
500_G504_D1.8911.00
538_P543_I1.8861.00
115_A145_L1.8771.00
37_K180_E1.8771.00
163_L167_E1.8731.00
205_I218_A1.8671.00
86_I105_C1.8571.00
321_R338_A1.8471.00
229_P247_V1.8371.00
385_Y410_E1.8281.00
422_N448_N1.8171.00
224_E291_A1.8141.00
535_F547_I1.8001.00
428_V473_T1.7961.00
155_Q159_D1.7861.00
107_G190_V1.7841.00
556_M559_N1.7831.00
422_N450_V1.7781.00
415_K482_E1.7781.00
500_G503_I1.7761.00
524_E527_K1.7711.00
497_M500_G1.7631.00
438_N455_D1.7481.00
56_L64_I1.7401.00
494_M510_V1.7311.00
416_A456_M1.6931.00
13_R81_Y1.6861.00
431_L468_Q1.6731.00
559_N564_C1.6731.00
430_E434_G1.6711.00
180_E184_E1.6611.00
325_E338_A1.6581.00
455_D485_G1.6491.00
425_V450_V1.6451.00
164_D167_E1.6421.00
209_L219_Y1.6401.00
233_I244_V1.6311.00
444_Y450_V1.6311.00
59_E367_R1.6231.00
218_A278_T1.6161.00
227_V244_V1.6111.00
56_L360_I1.6011.00
385_Y407_E1.5981.00
163_L166_S1.5881.00
534_Q556_M1.5771.00
37_K179_I1.5731.00
499_N503_I1.5601.00
385_Y391_K1.5441.00
561_L564_C1.5431.00
383_D391_K1.5331.00
56_L364_R1.5271.00
321_R325_E1.5251.00
54_M65_K1.5161.00
115_A147_S1.5091.00
337_E349_R1.5051.00
152_R156_E1.5001.00
437_G456_M1.4981.00
232_K243_E1.4901.00
109_I139_V1.4871.00
337_E351_G1.4811.00
228_K231_Q1.4741.00
149_E153_V1.4621.00
125_N128_L1.4611.00
171_A178_G1.4601.00
222_V266_G1.4541.00
111_V173_A1.4521.00
17_F186_I1.4521.00
302_N335_Q1.4481.00
497_M502_K1.4451.00
53_S67_N1.4421.00
112_V122_T1.4291.00
13_R80_E1.4151.00
497_M504_D1.4031.00
41_I47_K1.4021.00
201_L233_I1.4021.00
512_R521_V1.4001.00
499_N502_K1.3991.00
108_A134_L1.3751.00
195_G262_V1.3731.00
468_Q472_S1.3631.00
286_S289_N1.3631.00
501_E504_D1.3621.00
536_E554_K1.3621.00
114_A140_I1.3601.00
70_Q82_I1.3531.00
497_M501_E1.3431.00
195_G224_E1.3431.00
413_Y484_I1.3351.00
363_E367_R1.3261.00
328_E334_L1.3211.00
34_I71_L1.3200.99
389_G407_E1.3180.99
229_P256_P1.3140.99
496_I499_N1.3130.99
139_V173_A1.3070.99
240_K277_D1.3070.99
506_L510_V1.3040.99
35_L40_A1.2990.99
316_K319_D1.2950.99
201_L222_V1.2920.99
413_Y490_K1.2920.99
501_E505_A1.2910.99
513_D516_Y1.2900.99
499_N504_D1.2900.99
34_I179_I1.2860.99
415_K455_D1.2680.99
414_V461_I1.2650.99
420_V477_A1.2620.99
499_N505_A1.2610.99
419_M451_S1.2610.99
484_I487_K1.2560.99
507_S511_H1.2550.99
178_G181_E1.2500.99
502_K505_A1.2470.99
150_P153_V1.2430.99
523_V527_K1.2370.99
40_A71_L1.2320.99
538_P555_A1.2240.99
497_M503_I1.2240.99
279_R300_K1.2230.99
316_K372_D1.2210.99
41_I44_R1.2140.99
282_D297_G1.2020.99
516_Y520_K1.2020.99
417_T451_S1.1960.99
432_C456_M1.1940.99
28_S31_A1.1930.99
201_L227_V1.1930.99
560_V563_K1.1920.99
197_P262_V1.1840.99
355_M464_E1.1790.99
216_V329_L1.1770.99
137_L185_Q1.1700.99
167_E189_K1.1660.99
30_L111_V1.1630.99
494_M508_F1.1610.99
234_K290_P1.1580.99
71_L85_L1.1560.99
16_N84_H1.1550.99
430_E433_Q1.1550.99
158_E165_A1.1520.99
429_M439_F1.1480.99
334_L361_I1.1450.99
418_M428_V1.1440.99
556_M564_C1.1410.99
513_D563_K1.1400.99
242_F275_V1.1380.98
496_I500_G1.1320.98
520_K551_S1.1290.98
417_T453_I1.1260.98
439_F442_M1.1260.98
178_G182_I1.1200.98
165_A168_A1.1160.98
140_I170_L1.1140.98
236_M285_T1.1130.98
236_M294_A1.1110.98
465_F472_S1.1110.98
341_S345_G1.1100.98
126_V130_L1.1030.98
241_E287_A1.1020.98
113_D116_Q1.1010.98
382_Y486_Y1.1000.98
36_E43_Q1.0990.98
500_G505_A1.0990.98
73_Y184_E1.0980.98
517_E521_V1.0960.98
18_S102_L1.0940.98
384_V409_V1.0930.98
55_D367_R1.0890.98
523_V551_S1.0880.98
503_I544_G1.0860.98
74_K184_E1.0770.98
285_T290_P1.0750.98
21_A24_D1.0680.98
51_L69_V1.0660.98
175_A179_I1.0660.98
31_A85_L1.0650.98
38_T183_L1.0650.98
418_M432_C1.0620.98
15_R193_P1.0620.98
45_E253_K1.0600.98
306_Y351_G1.0550.98
56_L60_R1.0530.98
421_P476_Y1.0500.97
312_I372_D1.0470.97
496_I503_I1.0460.97
323_A365_I1.0460.97
362_Q375_T1.0430.97
30_L182_I1.0420.97
276_G328_E1.0390.97
130_L161_I1.0340.97
410_E488_P1.0340.97
202_K291_A1.0330.97
257_T260_L1.0330.97
499_N507_S1.0320.97
416_A481_Y1.0320.97
30_L173_A1.0310.97
524_E551_S1.0290.97
203_A220_I1.0200.97
429_M452_I1.0160.97
14_I264_D1.0130.97
386_M390_E1.0120.97
519_G541_A1.0100.97
512_R547_I1.0090.97
55_D59_E1.0060.97
158_E163_L1.0060.97
387_T407_E1.0060.97
222_V227_V1.0030.97
552_T555_A1.0010.97
18_S105_C0.9950.96
496_I502_K0.9940.96
234_K287_A0.9930.96
496_I501_E0.9920.96
506_L509_I0.9920.96
494_M500_G0.9920.96
423_D474_K0.9900.96
198_E226_T0.9850.96
497_M542_A0.9790.96
227_V247_V0.9790.96
285_T291_A0.9770.96
114_A148_A0.9750.96
44_R47_K0.9740.96
415_K440_I0.9730.96
163_L168_A0.9720.96
416_A432_C0.9720.96
552_T556_M0.9720.96
248_G257_T0.9700.96
247_V258_N0.9700.96
249_V257_T0.9680.96
195_G199_A0.9660.96
274_N277_D0.9660.96
291_A294_A0.9640.96
521_V524_E0.9630.96
171_A175_A0.9600.96
233_I284_I0.9590.96
506_L511_H0.9570.96
140_I150_P0.9540.96
558_K563_K0.9540.96
260_L264_D0.9500.95
137_L169_V0.9470.95
425_V442_M0.9460.95
140_I154_R0.9450.95
494_M503_I0.9450.95
236_M291_A0.9430.95
19_I31_A0.9390.95
465_F469_L0.9380.95
314_T374_I0.9360.95
229_P245_T0.9350.95
234_K239_G0.9340.95
495_D500_G0.9310.95
217_V271_S0.9300.95
200_P289_N0.9270.95
214_R246_E0.9260.95
382_Y489_S0.9160.94
131_D299_R0.9160.94
339_E347_G0.9150.94
494_M497_M0.9140.94
182_I186_I0.9130.94
54_M364_R0.9100.94
232_K287_A0.9080.94
494_M499_N0.9010.94
331_D357_H0.8970.94
20_I129_A0.8890.93
514_Y517_E0.8890.93
34_I83_F0.8880.93
172_S175_A0.8850.93
513_D564_C0.8840.93
41_I45_E0.8830.93
411_E436_R0.8820.93
498_L539_V0.8810.93
413_Y485_G0.8800.93
319_D323_A0.8790.93
72_K82_I0.8790.93
31_A51_L0.8750.93
382_Y391_K0.8750.93
510_V523_V0.8730.93
20_I110_L0.8720.93
333_S361_I0.8710.93
20_I108_A0.8700.93
442_M450_V0.8690.93
503_I507_S0.8690.93
171_A177_I0.8670.93
433_Q454_Y0.8660.93
49_Q58_R0.8660.93
47_K50_L0.8620.92
490_K513_D0.8620.92
201_L244_V0.8610.92
34_I183_L0.8560.92
525_K528_E0.8560.92
65_K69_V0.8550.92
83_F183_L0.8530.92
107_G191_P0.8510.92
38_T71_L0.8510.92
516_Y561_L0.8510.92
542_A547_I0.8500.92
538_P552_T0.8450.92
494_M504_D0.8430.92
556_M563_K0.8420.92
391_K410_E0.8390.91
109_I169_V0.8370.91
523_V539_V0.8360.91
150_P170_L0.8330.91
11_Q195_G0.8320.91
438_N490_K0.8310.91
203_A222_V0.8280.91
110_L122_T0.8270.91
235_M284_I0.8250.91
220_I272_I0.8230.91
435_K464_E0.8180.90
305_V462_V0.8180.90
229_P246_E0.8170.90
82_I264_D0.8170.90
362_Q373_L0.8150.90
521_V547_I0.8110.90
201_L226_T0.8100.90
74_K187_V0.8080.90
322_E325_E0.8080.90
382_Y459_A0.8070.90
74_K180_E0.8050.90
70_Q84_H0.8050.90
55_D58_R0.8020.89
325_E336_Y0.8020.89
413_Y489_S0.8010.89
169_V189_K0.8000.89
217_V254_A0.8000.89
209_L439_F0.7990.89
228_K258_N0.7980.89
47_K58_R0.7940.89
22_H25_H0.7920.89
427_A472_S0.7910.89
424_Y476_Y0.7900.89
113_D153_V0.7880.89
310_Y313_D0.7860.88
200_P286_S0.7860.88
151_E155_Q0.7840.88
435_K468_Q0.7840.88
237_A240_K0.7790.88
515_A547_I0.7790.88
35_L69_V0.7770.88
391_K408_R0.7760.88
102_L132_N0.7760.88
95_T128_L0.7720.88
150_P154_R0.7710.88
71_L83_F0.7710.88
169_V178_G0.7710.88
103_A223_V0.7710.88
445_L451_S0.7700.87
218_A272_I0.7670.87
172_S177_I0.7660.87
286_S290_P0.7650.87
286_S291_A0.7640.87
538_P550_R0.7630.87
54_M64_I0.7630.87
520_K549_A0.7630.87
494_M501_E0.7620.87
237_A282_D0.7620.87
320_L371_I0.7620.87
428_V469_L0.7600.87
204_L297_G0.7600.87
365_I371_I0.7590.87
183_L187_V0.7590.87
432_C454_Y0.7580.87
515_A521_V0.7560.86
158_E168_A0.7560.86
517_E539_V0.7550.86
62_I356_L0.7540.86
418_M477_A0.7500.86
560_V564_C0.7480.86
127_Y449_R0.7480.86
235_M278_T0.7470.86
261_T264_D0.7460.86
307_C350_C0.7440.86
132_N223_V0.7400.85
436_R460_E0.7400.85
49_Q145_L0.7380.85
66_L101_S0.7370.85
107_G193_P0.7370.85
500_G507_S0.7370.85
35_L50_L0.7360.85
317_Y321_R0.7350.85
127_Y131_D0.7340.85
17_F31_A0.7340.85
527_K533_Q0.7340.85
24_D62_I0.7320.85
123_L127_Y0.7320.85
533_Q538_P0.7310.85
420_V424_Y0.7290.84
56_L363_E0.7280.84
306_Y349_R0.7270.84
469_L473_T0.7260.84
147_S150_P0.7240.84
64_I367_R0.7210.84
513_D562_A0.7210.84
114_A143_I0.7200.84
103_A298_Y0.7160.83
30_L179_I0.7160.83
550_R553_I0.7160.83
137_L189_K0.7140.83
149_E156_E0.7140.83
60_R359_E0.7120.83
309_L373_L0.7120.83
42_T47_K0.7110.83
493_K503_I0.7100.83
139_V182_I0.7100.83
422_N425_V0.7100.83
334_L357_H0.7090.83
494_M502_K0.7090.83
222_V262_V0.7080.83
227_V272_I0.7080.83
465_F477_A0.7070.83
201_L284_I0.7060.82
437_G454_Y0.7040.82
275_V278_T0.7040.82
158_E164_D0.7040.82
493_K500_G0.7040.82
304_M414_V0.7010.82
550_R559_N0.7000.82
185_Q188_E0.7000.82
56_L67_N0.6990.82
48_E58_R0.6990.82
517_E520_K0.6970.82
328_E336_Y0.6960.82
83_F187_V0.6940.81
501_E507_S0.6930.81
169_V182_I0.6910.81
414_V479_F0.6910.81
309_L350_C0.6900.81
15_R107_G0.6890.81
425_V429_M0.6880.81
235_M242_F0.6880.81
502_K507_S0.6870.81
416_A437_G0.6870.81
129_A136_I0.6830.80
226_T262_V0.6830.80
162_G167_E0.6800.80
339_E345_G0.6800.80
197_P261_T0.6790.80
338_A345_G0.6770.80
17_F85_L0.6770.80
383_D408_R0.6760.80
173_A182_I0.6760.80
439_F454_Y0.6750.80
122_T138_P0.6740.80
497_M505_A0.6730.79
496_I504_D0.6720.79
138_P157_V0.6720.79
231_Q244_V0.6700.79
69_V250_F0.6690.79
414_V458_L0.6690.79
119_E145_L0.6680.79
51_L63_T0.6670.79
54_M367_R0.6660.79
70_Q264_D0.6660.79
310_Y374_I0.6660.79
197_P226_T0.6640.78
15_R192_A0.6630.78
34_I109_I0.6630.78
414_V456_M0.6610.78
503_I508_F0.6610.78
553_I558_K0.6610.78
542_A546_K0.6600.78
483_L486_Y0.6600.78
106_E221_R0.6590.78
424_Y474_K0.6590.78
341_S346_F0.6580.78
308_G347_G0.6540.77
351_G357_H0.6540.77
500_G508_F0.6540.77
173_A179_I0.6540.77
533_Q537_V0.6520.77
500_G538_P0.6490.77
243_E246_E0.6480.77
137_L190_V0.6470.77
38_T73_Y0.6460.77
413_Y455_D0.6450.76
35_L41_I0.6420.76
321_R348_F0.6410.76
53_S253_K0.6410.76
295_L298_Y0.6410.76
424_Y427_A0.6410.76
523_V547_I0.6400.76
275_V371_I0.6400.76
514_Y549_A0.6370.76
24_D29_T0.6370.76
203_A272_I0.6350.75
317_Y348_F0.6340.75
556_M561_L0.6340.75
534_Q555_A0.6340.75
127_Y162_G0.6320.75
385_Y388_D0.6320.75
319_D322_E0.6320.75
391_K407_E0.6320.75
227_V231_Q0.6310.75
101_S105_C0.6310.75
529_L533_Q0.6310.75
364_R368_E0.6290.75
489_S492_V0.6290.75
558_K562_A0.6280.75
310_Y347_G0.6260.74
325_E328_E0.6240.74
349_R379_S0.6240.74
417_T482_E0.6230.74
170_L178_G0.6200.74
362_Q366_E0.6190.74
422_N447_A0.6180.73
202_K290_P0.6170.73
505_A515_A0.6160.73
307_C375_T0.6150.73
538_P541_A0.6150.73
216_V278_T0.6140.73
220_I266_G0.6140.73
125_N129_A0.6140.73
153_V156_E0.6120.73
251_T255_T0.6110.73
361_I365_I0.6110.73
363_E366_E0.6100.72
244_V247_V0.6090.72
387_T391_K0.6080.72
304_M479_F0.6080.72
18_S132_N0.6080.72
15_R191_P0.6080.72
37_K171_A0.6060.72
62_I91_H0.6060.72
425_V452_I0.6050.72
425_V439_F0.6030.72
520_K552_T0.6030.72
434_G468_Q0.6020.71
504_D508_F0.6020.71
15_R19_I0.6010.71
340_T346_F0.6000.71
334_L350_C0.5990.71
155_Q158_E0.5990.71
496_I505_A0.5990.71
508_F528_E0.5980.71
68_S219_Y0.5970.71
56_L367_R0.5970.71
242_F278_T0.5960.71
313_D316_K0.5960.71
504_D507_S0.5960.71
50_L253_K0.5950.71
239_G282_D0.5950.71
539_V554_K0.5950.71
307_C473_T0.5940.70
440_I484_I0.5940.70
23_I54_M0.5940.70
173_A178_G0.5930.70
311_P376_T0.5920.70
202_K223_V0.5920.70
19_I25_H0.5900.70
538_P553_I0.5900.70
37_K178_G0.5900.70
318_N322_E0.5890.70
287_A290_P0.5890.70
515_A543_I0.5880.70
135_E167_E0.5870.70
539_V553_I0.5870.70
30_L139_V0.5850.69
222_V226_T0.5840.69
199_A291_A0.5840.69
11_Q197_P0.5840.69
63_T121_Q0.5840.69
33_R176_G0.5840.69
18_S186_I0.5830.69
312_I374_I0.5830.69
550_R564_C0.5820.69
71_L183_L0.5820.69
218_A359_E0.5820.69
461_I479_F0.5810.69
219_Y439_F0.5810.69
240_K244_V0.5800.69
519_G542_A0.5800.69
555_A559_N0.5790.69
95_T301_L0.5790.69
92_V124_A0.5780.68
410_E486_Y0.5780.68
218_A316_K0.5770.68
505_A547_I0.5760.68
211_D217_V0.5760.68
536_E552_T0.5750.68
238_T297_G0.5750.68
214_R254_A0.5750.68
168_A177_I0.5730.68
553_I556_M0.5710.67
119_E357_H0.5710.67
494_M505_A0.5700.67
443_Q453_I0.5690.67
495_D499_N0.5690.67
493_K497_M0.5680.67
390_E407_E0.5680.67
512_R516_Y0.5670.67
384_V406_I0.5670.67
110_L136_I0.5660.67
440_I453_I0.5660.67
339_E349_R0.5650.67
550_R556_M0.5650.67
74_K183_L0.5630.66
34_I38_T0.5630.66
70_Q257_T0.5630.66
146_P172_S0.5630.66
201_L231_Q0.5620.66
220_I260_L0.5610.66
24_D91_H0.5610.66
11_Q14_I0.5610.66
56_L110_L0.5610.66
179_I183_L0.5600.66
420_V452_I0.5600.66
140_I462_V0.5600.66
359_E362_Q0.5600.66
170_L177_I0.5590.66
384_V390_E0.5580.66
328_E350_C0.5570.66
24_D63_T0.5570.66
162_G166_S0.5570.66
207_D544_G0.5560.65
42_T58_R0.5560.65
66_L209_L0.5560.65
493_K502_K0.5550.65
503_I547_I0.5540.65
96_Y99_S0.5530.65
151_E170_L0.5530.65
285_T289_N0.5510.65
11_Q261_T0.5510.65
15_R25_H0.5500.65
509_I523_V0.5500.65
419_M445_L0.5490.64
20_I102_L0.5480.64
521_V545_Q0.5470.64
360_I364_R0.5470.64
130_L136_I0.5460.64
556_M562_A0.5460.64
558_K564_C0.5460.64
86_I134_L0.5450.64
211_D214_R0.5450.64
157_V163_L0.5450.64
189_K192_A0.5450.64
160_V168_A0.5430.64
493_K504_D0.5420.63
227_V233_I0.5420.63
327_L365_I0.5420.63
390_E410_E0.5410.63
118_I160_V0.5410.63
99_S125_N0.5410.63
498_L505_A0.5400.63
126_V136_I0.5390.63
428_V452_I0.5390.63
60_R221_R0.5390.63
39_S42_T0.5380.63
115_A150_P0.5380.63
36_E46_M0.5380.63
25_H32_D0.5380.63
38_T206_F0.5370.63
74_K81_Y0.5360.63
501_E534_Q0.5350.62
168_A171_A0.5350.62
234_K285_T0.5350.62
429_M442_M0.5350.62
504_D549_A0.5340.62
505_A550_R0.5330.62
115_A119_E0.5310.62
196_D262_V0.5310.62
34_I182_I0.5310.62
136_I481_Y0.5300.62
310_Y554_K0.5300.62
306_Y381_I0.5300.62
388_D410_E0.5300.62
508_F518_R0.5300.62
206_F219_Y0.5290.62
429_M477_A0.5290.62
409_V489_S0.5280.61
23_I63_T0.5280.61
336_Y348_F0.5280.61
466_F470_K0.5270.61
123_L449_R0.5270.61
514_Y521_V0.5260.61
385_Y488_P0.5250.61
522_I537_V0.5240.61
418_M465_F0.5230.61
18_S71_L0.5230.61
495_D505_A0.5230.61
183_L186_I0.5220.61
547_I563_K0.5210.60
521_V534_Q0.5200.60
336_Y350_C0.5200.60
504_D511_H0.5200.60
196_D226_T0.5200.60
24_D61_G0.5190.60
508_F519_G0.5170.60
487_K490_K0.5170.60
242_F245_T0.5150.60
407_E410_E0.5140.59
126_V165_A0.5130.59
493_K499_N0.5130.59
223_V295_L0.5120.59
531_P544_G0.5120.59
346_F555_A0.5110.59
20_I131_D0.5110.59
425_V444_Y0.5100.59
516_Y524_E0.5100.59
179_I185_Q0.5090.59
126_V160_V0.5090.59
517_E527_K0.5090.59
552_T558_K0.5080.59
524_E552_T0.5080.59
358_M559_N0.5080.59
307_C373_L0.5080.59
456_M461_I0.5070.58
387_T390_E0.5060.58
520_K524_E0.5060.58
53_S251_T0.5060.58
227_V266_G0.5060.58
254_A271_S0.5050.58
157_V161_I0.5050.58
518_R521_V0.5050.58
86_I101_S0.5040.58
246_E273_K0.5040.58
33_R172_S0.5030.58
504_D547_I0.5030.58
106_E223_V0.5030.58
430_E439_F0.5030.58
509_I528_E0.5030.58
17_F28_S0.5020.58
543_I547_I0.5020.58
20_I137_L0.5020.58
103_A132_N0.5020.58
138_P168_A0.5010.57
38_T72_K0.5010.57
48_E520_K0.5000.57
43_Q46_M0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2yweA 1 0.8546 100 0.189 Contact Map
3cb4D 1 0.8562 100 0.19 Contact Map
4qjty 1 0.9412 100 0.203 Contact Map
4zciA 1 0.8529 100 0.369 Contact Map
4kiyV 1 0.7794 100 0.404 Contact Map
1darA 1 0.6699 100 0.409 Contact Map
2xexA 1 0.768 100 0.41 Contact Map
4w224 1 0.8399 100 0.411 Contact Map
3j25A 1 0.7925 100 0.416 Contact Map
1n0uA 1 0.8072 100 0.417 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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