LON1 - BACSU - GREMLIN Contacts

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LON1 - Lon protease 1

UniProt:	P37945	Sequences: MAEELKRSIPLLPLRGLLVYPTMVLHLDVGRDKSVQALEQAMMHDHMIFLATQQDISIDEPGEDEIFTVGTYTKIKQMLKLPNGTIRVLVEGLKRAHIVKYNEHEDYTSVDIQLIHEDDSKDTEDEALMRTLLDHFDQYIKISKKISAETYAAVTDIEEPGRMADIVASHLPLKLKDKQDILETADVKDRLNKVIDFINNEKEVLEIEKKIGQRVKRSMERTQKEYYLREQMKAIQKELGDKEGKTGEVQTLTEKIEEAGMPDHVKETALKELNRYEKIPSSSAESSVIRNYIDWLVALPWTDETDDKLDLKEAGRLLDEEHHGLEKVKERILEYLAVQKLTKSLKGPILCLAGPPGVGKTSLAKSIAKSLGRKFVRISLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAGKLNPVFLLDEIDKMSSDFRGDPSSAMLEVLDPEQNSSFSDHYIEETFDLSKVLFIATANNLATIPGPLRDRMEIINIAGYTEIEKLEIVKDHLLPKQIKEHGLKKSNLQLRDQAILDIIRYYTREAGVRSLERQLAAICRKAAKAIVAEERKRITVTEKNLQDFIGKRIFRYGQAETEDQVGVVTGLAYTTVGGDTLSIEVSLSPGKGKLILTGKLGDVMRESAQAAFSYVRSKTEELGIEPDFHEKYDIHIHVPEGAVPKDGPSAGITMATALVSALTGRAVSREVGMTGEITLRGRVLPIGGLKEKALGAHRAGLTTIIAPKDNEKDIEDIPESVREGLTFILASHLDEVLEHALVGEKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	774 (763)
Sequences:	3203 (1837)
Seq/√Len:	66.5

ECOLI - LON
BACSU - LON1 LON2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
714_I	717_L	5.279	1.00
736_K	739_E	4.839	1.00
315_G	319_D	4.692	1.00
502_K	524_D	4.670	1.00
736_K	759_S	4.550	1.00
305_T	413_K	4.434	1.00
320_E	369_K	4.159	1.00
49_F	96_A	3.747	1.00
731_T	756_I	3.601	1.00
341_L	555_A	3.591	1.00
499_E	503_D	3.547	1.00
407_G	418_F	3.440	1.00
99_V	113_Q	3.385	1.00
506_L	522_L	3.373	1.00
100_K	111_D	3.184	1.00
613_V	685_A	3.123	1.00
254_E	258_E	3.068	1.00
321_E	369_K	3.052	1.00
184_T	189_D	3.052	1.00
405_I	459_F	3.043	1.00
747_E	750_R	3.035	1.00
734_A	757_L	3.006	1.00
97_H	113_Q	2.994	1.00
557_A	575_D	2.983	1.00
756_I	767_H	2.963	1.00
630_D	633_R	2.959	1.00
550_I	568_V	2.919	1.00
721_A	755_F	2.822	1.00
731_T	754_T	2.813	1.00
523_R	526_A	2.808	1.00
700_G	729_L	2.780	1.00
269_A	296_L	2.768	1.00
529_D	533_Y	2.762	1.00
758_A	763_E	2.711	1.00
304_E	463_K	2.710	1.00
725_H	752_G	2.700	1.00
698_E	730_T	2.696	1.00
506_L	547_L	2.692	1.00
569_T	572_N	2.663	1.00
253_T	277_E	2.657	1.00
426_M	438_M	2.611	1.00
655_D	659_K	2.596	1.00
304_E	414_L	2.589	1.00
263_D	267_E	2.576	1.00
256_I	269_A	2.557	1.00
165_D	190_R	2.518	1.00
256_I	273_L	2.489	1.00
414_L	459_F	2.466	1.00
717_L	734_A	2.460	1.00
9_I	72_Y	2.410	1.00
680_I	764_V	2.402	1.00
624_L	636_A	2.376	1.00
315_G	560_A	2.365	1.00
180_D	193_K	2.363	1.00
266_K	270_L	2.350	1.00
72_Y	96_A	2.342	1.00
522_L	550_I	2.338	1.00
733_I	767_H	2.327	1.00
530_I	550_I	2.309	1.00
513_H	548_A	2.303	1.00
262_P	265_V	2.301	1.00
742_I	757_L	2.298	1.00
763_E	766_E	2.289	1.00
646_K	649_E	2.285	1.00
556_K	560_A	2.277	1.00
520_L	551_C	2.235	1.00
51_A	98_I	2.225	1.00
313_E	316_R	2.181	1.00
305_T	374_K	2.166	1.00
619_K	658_E	2.165	1.00
299_L	459_F	2.140	1.00
731_T	767_H	2.139	1.00
733_I	758_A	2.108	1.00
646_K	762_D	2.107	1.00
296_L	457_E	2.106	1.00
11_L	110_V	2.100	1.00
259_A	303_D	2.100	1.00
530_I	577_I	2.073	1.00
495_I	748_S	2.069	1.00
31_R	53_Q	2.068	1.00
408_M	459_F	2.058	1.00
533_Y	580_R	2.056	1.00
683_A	705_I	2.047	1.00
481_R	486_I	2.036	1.00
498_L	528_L	2.029	1.00
51_A	66_I	1.999	1.00
494_E	532_R	1.989	1.00
509_Q	548_A	1.968	1.00
316_R	320_E	1.964	1.00
739_E	757_L	1.914	1.00
312_K	560_A	1.894	1.00
352_L	367_I	1.890	1.00
633_R	637_Q	1.890	1.00
620_G	661_D	1.889	1.00
228_L	235_I	1.882	1.00
308_K	313_E	1.877	1.00
179_Q	183_E	1.872	1.00
261_M	297_V	1.871	1.00
473_L	486_I	1.870	1.00
684_T	768_A	1.866	1.00
693_R	769_L	1.858	1.00
758_A	764_V	1.853	1.00
103_E	106_D	1.852	1.00
376_V	411_A	1.851	1.00
506_L	527_I	1.851	1.00
529_D	570_E	1.831	1.00
186_D	189_D	1.817	1.00
747_E	751_E	1.816	1.00
177_D	180_D	1.812	1.00
414_L	463_K	1.810	1.00
313_E	317_L	1.809	1.00
529_D	580_R	1.808	1.00
572_N	576_F	1.807	1.00
253_T	270_L	1.804	1.00
384_R	453_H	1.800	1.00
333_L	556_K	1.798	1.00
257_E	266_K	1.793	1.00
374_K	413_K	1.793	1.00
699_V	731_T	1.791	1.00
11_L	49_F	1.788	1.00
389_I	441_V	1.788	1.00
71_T	92_G	1.781	1.00
529_D	573_L	1.779	1.00
613_V	689_A	1.779	1.00
591_D	770_V	1.775	1.00
74_K	93_L	1.767	1.00
376_V	418_F	1.765	1.00
124_E	188_K	1.759	1.00
499_E	502_K	1.759	1.00
705_I	761_L	1.756	1.00
261_M	269_A	1.752	1.00
687_V	765_L	1.750	1.00
256_I	270_L	1.739	1.00
608_T	727_A	1.721	1.00
714_I	734_A	1.695	0.99
177_D	200_N	1.692	0.99
30_G	34_S	1.675	0.99
478_G	481_R	1.674	0.99
684_T	764_V	1.658	0.99
557_A	576_F	1.654	0.99
232_M	235_I	1.649	0.99
516_K	519_N	1.643	0.99
554_A	566_I	1.642	0.99
498_L	524_D	1.639	0.99
509_Q	544_E	1.636	0.99
615_L	689_A	1.634	0.99
666_V	682_M	1.632	0.99
164_A	191_L	1.625	0.99
759_S	763_E	1.620	0.99
526_A	573_L	1.615	0.99
508_K	544_E	1.615	0.99
380_L	420_L	1.614	0.99
58_I	65_E	1.605	0.99
374_K	412_G	1.602	0.99
721_A	732_I	1.599	0.99
367_I	467_I	1.594	0.99
33_K	60_E	1.594	0.99
734_A	742_I	1.594	0.99
260_G	302_T	1.591	0.99
593_V	692_G	1.584	0.99
98_I	110_V	1.581	0.99
267_E	412_G	1.578	0.99
523_R	567_T	1.568	0.99
138_Q	206_E	1.568	0.99
117_E	161_G	1.566	0.99
733_I	764_V	1.566	0.99
31_R	34_S	1.561	0.99
714_I	721_A	1.558	0.99
118_D	186_D	1.552	0.99
451_S	458_T	1.552	0.99
520_L	550_I	1.550	0.99
683_A	761_L	1.550	0.99
616_S	641_S	1.543	0.99
680_I	758_A	1.538	0.99
472_N	475_T	1.527	0.99
521_Q	567_T	1.524	0.99
95_R	190_R	1.523	0.99
502_K	527_I	1.520	0.99
94_K	114_L	1.518	0.99
521_Q	565_R	1.516	0.99
750_R	755_F	1.514	0.99
165_D	185_A	1.506	0.99
256_I	261_M	1.495	0.99
15_R	31_R	1.470	0.98
68_T	97_H	1.468	0.98
717_L	757_L	1.467	0.98
623_I	637_Q	1.465	0.98
721_A	734_A	1.458	0.98
31_R	61_P	1.456	0.98
263_D	266_K	1.454	0.98
48_I	73_T	1.447	0.98
557_A	562_E	1.443	0.98
132_L	191_L	1.434	0.98
8_S	111_D	1.434	0.98
546_Q	581_I	1.432	0.98
642_Y	761_L	1.432	0.98
72_Y	94_K	1.430	0.98
327_K	549_A	1.429	0.98
63_E	101_Y	1.425	0.98
394_R	456_E	1.419	0.98
530_I	547_L	1.418	0.98
69_V	185_A	1.414	0.98
696_S	731_T	1.413	0.98
302_T	414_L	1.408	0.98
261_M	296_L	1.408	0.98
649_E	762_D	1.404	0.98
384_R	387_S	1.398	0.98
269_A	293_I	1.397	0.98
161_G	164_A	1.396	0.98
554_A	558_I	1.391	0.98
680_I	711_V	1.387	0.98
509_Q	547_L	1.385	0.98
275_R	291_N	1.383	0.98
295_W	406_Q	1.380	0.98
15_R	53_Q	1.377	0.98
216_K	220_E	1.374	0.98
615_L	660_Y	1.370	0.98
717_L	721_A	1.361	0.97
624_L	633_R	1.360	0.97
317_L	369_K	1.357	0.97
640_F	662_I	1.350	0.97
330_E	553_K	1.348	0.97
591_D	697_R	1.345	0.97
526_A	570_E	1.343	0.97
214_R	237_K	1.343	0.97
181_I	194_V	1.339	0.97
328_V	352_L	1.332	0.97
684_T	695_V	1.332	0.97
627_K	630_D	1.331	0.97
643_V	687_V	1.327	0.97
584_Y	607_D	1.323	0.97
618_G	661_D	1.319	0.97
734_A	755_F	1.314	0.97
184_T	193_K	1.312	0.97
611_I	681_T	1.310	0.97
583_R	737_D	1.307	0.97
66_I	98_I	1.302	0.97
260_G	306_D	1.301	0.97
161_G	165_D	1.299	0.97
142_I	205_L	1.298	0.97
662_I	690_L	1.295	0.97
739_E	743_E	1.292	0.97
252_L	294_D	1.290	0.96
55_D	58_I	1.287	0.96
69_V	115_I	1.287	0.96
49_F	112_I	1.284	0.96
662_I	686_L	1.282	0.96
95_R	165_D	1.282	0.96
553_K	576_F	1.280	0.96
599_L	732_I	1.279	0.96
546_Q	549_A	1.278	0.96
256_I	297_V	1.277	0.96
341_L	558_I	1.265	0.96
375_F	419_L	1.263	0.96
221_R	225_E	1.263	0.96
130_R	201_E	1.258	0.96
498_L	531_I	1.253	0.96
572_N	575_D	1.251	0.96
524_D	528_L	1.251	0.96
269_A	273_L	1.245	0.96
423_I	438_M	1.245	0.96
132_L	198_I	1.241	0.96
378_I	407_G	1.236	0.95
15_R	30_G	1.232	0.95
522_L	573_L	1.231	0.95
522_L	547_L	1.231	0.95
364_A	419_L	1.229	0.95
525_Q	570_E	1.228	0.95
8_S	109_S	1.228	0.95
596_V	681_T	1.225	0.95
628_L	666_V	1.224	0.95
315_G	333_L	1.221	0.95
315_G	556_K	1.219	0.95
636_A	664_I	1.217	0.95
721_A	753_L	1.213	0.95
656_F	690_L	1.210	0.95
284_A	397_V	1.202	0.95
574_Q	743_E	1.201	0.95
657_H	690_L	1.200	0.95
259_A	262_P	1.195	0.95
259_A	269_A	1.192	0.95
647_T	652_I	1.190	0.94
579_K	743_E	1.188	0.94
371_L	465_L	1.186	0.94
50_L	73_T	1.185	0.94
346_K	512_E	1.185	0.94
98_I	101_Y	1.182	0.94
34_S	53_Q	1.177	0.94
341_L	559_V	1.177	0.94
260_G	263_D	1.166	0.94
37_A	41_A	1.165	0.94
299_L	405_I	1.165	0.94
210_K	214_R	1.161	0.94
160_P	164_A	1.159	0.94
542_S	545_R	1.158	0.94
758_A	767_H	1.148	0.93
765_L	769_L	1.148	0.93
328_V	489_I	1.148	0.93
520_L	554_A	1.145	0.93
47_M	93_L	1.141	0.93
135_H	195_I	1.140	0.93
307_D	371_L	1.138	0.93
258_E	263_D	1.136	0.93
40_Q	44_H	1.135	0.93
473_L	481_R	1.134	0.93
68_T	183_E	1.133	0.93
174_K	177_D	1.132	0.93
408_M	464_V	1.132	0.93
363_L	489_I	1.124	0.93
53_Q	61_P	1.123	0.93
760_H	763_E	1.123	0.93
30_G	53_Q	1.122	0.93
764_V	768_A	1.122	0.93
49_F	98_I	1.120	0.92
376_V	407_G	1.117	0.92
493_T	718_K	1.115	0.92
408_M	414_L	1.111	0.92
687_V	769_L	1.109	0.92
295_W	409_K	1.108	0.92
12_L	48_I	1.106	0.92
255_K	298_A	1.103	0.92
291_N	454_Y	1.102	0.92
568_V	573_L	1.100	0.92
160_P	191_L	1.100	0.92
742_I	755_F	1.098	0.92
509_Q	551_C	1.086	0.91
173_L	197_F	1.081	0.91
15_R	34_S	1.075	0.91
40_Q	107_Y	1.074	0.91
340_K	559_V	1.074	0.91
375_F	379_S	1.072	0.91
668_E	706_T	1.071	0.91
258_E	306_D	1.069	0.91
279_I	287_S	1.067	0.91
595_V	610_S	1.067	0.91
522_L	526_A	1.063	0.90
51_A	110_V	1.058	0.90
375_F	417_V	1.058	0.90
345_L	348_P	1.058	0.90
279_I	289_I	1.056	0.90
193_K	196_D	1.054	0.90
600_A	609_L	1.054	0.90
47_M	74_K	1.054	0.90
299_L	455_I	1.052	0.90
314_A	317_L	1.051	0.90
353_A	472_N	1.051	0.90
706_T	712_L	1.050	0.90
510_I	520_L	1.047	0.90
341_L	519_N	1.044	0.90
250_Q	253_T	1.043	0.89
52_T	175_L	1.042	0.89
523_R	569_T	1.040	0.89
203_E	206_E	1.038	0.89
353_A	473_L	1.035	0.89
19_V	73_T	1.035	0.89
250_Q	254_E	1.031	0.89
28_D	87_R	1.029	0.89
596_V	695_V	1.029	0.89
321_E	366_S	1.028	0.89
312_K	562_E	1.027	0.89
542_S	546_Q	1.026	0.89
314_A	336_L	1.025	0.89
323_H	499_E	1.021	0.88
96_A	112_I	1.021	0.88
270_L	273_L	1.020	0.88
311_L	337_A	1.011	0.88
554_A	576_F	1.010	0.88
544_E	548_A	1.009	0.88
377_R	484_M	1.009	0.88
39_E	80_K	1.007	0.88
307_D	415_N	1.004	0.88
475_T	481_R	1.004	0.88
61_P	65_E	1.004	0.88
303_D	306_D	1.002	0.88
699_V	767_H	1.000	0.87
646_K	650_L	0.998	0.87
129_M	133_L	0.997	0.87
683_A	687_V	0.995	0.87
263_D	306_D	0.993	0.87
132_L	195_I	0.992	0.87
445_E	508_K	0.991	0.87
652_I	691_T	0.991	0.87
279_I	286_S	0.989	0.87
273_L	297_V	0.984	0.87
131_T	195_I	0.981	0.86
334_E	556_K	0.978	0.86
353_A	481_R	0.977	0.86
730_T	752_G	0.977	0.86
383_V	453_H	0.973	0.86
11_L	96_A	0.972	0.86
599_L	700_G	0.971	0.86
225_E	239_L	0.966	0.86
296_L	455_I	0.966	0.86
523_R	571_K	0.965	0.85
38_L	86_I	0.964	0.85
63_E	68_T	0.961	0.85
510_I	517_K	0.958	0.85
122_D	188_K	0.958	0.85
253_T	257_E	0.956	0.85
650_L	687_V	0.955	0.85
622_L	640_F	0.955	0.85
249_V	273_L	0.955	0.85
243_E	246_T	0.954	0.85
223_Q	226_Y	0.952	0.85
742_I	745_I	0.952	0.85
617_P	660_Y	0.950	0.85
168_A	181_I	0.949	0.85
680_I	683_A	0.947	0.84
575_D	747_E	0.947	0.84
451_S	456_E	0.946	0.84
501_V	527_I	0.945	0.84
435_S	477_P	0.944	0.84
261_M	265_V	0.943	0.84
721_A	750_R	0.942	0.84
732_I	753_L	0.940	0.84
472_N	481_R	0.940	0.84
157_I	166_I	0.936	0.84
99_V	111_D	0.934	0.84
215_V	234_A	0.933	0.83
510_I	515_L	0.932	0.83
295_W	455_I	0.932	0.83
51_A	96_A	0.931	0.83
15_R	61_P	0.929	0.83
647_T	651_G	0.929	0.83
621_K	661_D	0.927	0.83
256_I	259_A	0.924	0.83
49_F	72_Y	0.923	0.83
642_Y	646_K	0.921	0.83
255_K	297_V	0.920	0.83
16_G	28_D	0.918	0.82
214_R	234_A	0.915	0.82
601_Y	723_G	0.914	0.82
600_A	723_G	0.914	0.82
127_A	130_R	0.913	0.82
732_I	755_F	0.913	0.82
26_H	76_K	0.911	0.82
365_K	445_E	0.909	0.82
11_L	51_A	0.909	0.82
115_I	185_A	0.906	0.82
761_L	765_L	0.905	0.82
644_R	656_F	0.903	0.81
235_I	239_L	0.903	0.81
607_D	611_I	0.901	0.81
219_M	226_Y	0.901	0.81
596_V	685_A	0.901	0.81
721_A	757_L	0.900	0.81
383_V	426_M	0.897	0.81
58_I	61_P	0.895	0.81
519_N	558_I	0.895	0.81
228_L	239_L	0.894	0.81
616_S	644_R	0.894	0.81
423_I	426_M	0.893	0.81
627_K	668_E	0.888	0.80
130_R	204_V	0.888	0.80
256_I	293_I	0.887	0.80
405_I	408_M	0.886	0.80
218_S	237_K	0.885	0.80
257_E	270_L	0.883	0.80
734_A	739_E	0.881	0.80
555_A	559_V	0.880	0.80
50_L	90_V	0.879	0.80
265_V	457_E	0.879	0.80
736_K	763_E	0.875	0.79
312_K	316_R	0.875	0.79
652_I	687_V	0.872	0.79
14_L	50_L	0.867	0.79
644_R	657_H	0.864	0.78
259_A	302_T	0.864	0.78
330_E	556_K	0.863	0.78
230_E	233_K	0.860	0.78
510_I	551_C	0.856	0.78
259_A	266_K	0.856	0.78
590_E	593_V	0.853	0.78
507_P	511_K	0.852	0.78
725_H	749_V	0.852	0.78
525_Q	571_K	0.849	0.77
687_V	761_L	0.849	0.77
140_I	146_I	0.848	0.77
231_Q	238_E	0.845	0.77
426_M	477_P	0.842	0.77
79_L	82_P	0.841	0.77
523_R	570_E	0.841	0.77
63_E	108_T	0.841	0.77
275_R	295_W	0.840	0.77
94_K	116_H	0.839	0.76
308_K	372_G	0.839	0.76
617_P	654_P	0.836	0.76
161_G	190_R	0.836	0.76
326_E	330_E	0.835	0.76
309_L	340_K	0.834	0.76
102_N	106_D	0.834	0.76
163_M	167_V	0.834	0.76
52_T	179_Q	0.834	0.76
509_Q	512_E	0.833	0.76
636_A	681_T	0.830	0.76
498_L	502_K	0.829	0.76
315_G	330_E	0.828	0.75
714_I	757_L	0.828	0.75
62_G	65_E	0.828	0.75
528_L	532_R	0.827	0.75
597_T	610_S	0.827	0.75
32_D	36_Q	0.826	0.75
494_E	528_L	0.825	0.75
323_H	503_D	0.823	0.75
11_L	108_T	0.823	0.75
317_L	320_E	0.822	0.75
251_T	271_K	0.819	0.75
696_S	768_A	0.819	0.75
24_V	76_K	0.818	0.75
363_L	406_Q	0.818	0.75
379_S	409_K	0.817	0.74
614_S	641_S	0.815	0.74
259_A	273_L	0.812	0.74
310_D	313_E	0.811	0.74
713_P	737_D	0.808	0.74
721_A	742_I	0.807	0.74
643_V	705_I	0.806	0.73
710_R	759_S	0.806	0.73
127_A	204_V	0.805	0.73
16_G	87_R	0.805	0.73
353_A	475_T	0.805	0.73
34_S	61_P	0.804	0.73
307_D	374_K	0.804	0.73
371_L	417_V	0.804	0.73
271_K	409_K	0.803	0.73
757_L	763_E	0.803	0.73
761_L	764_V	0.802	0.73
660_Y	690_L	0.799	0.73
622_L	636_A	0.796	0.73
302_T	459_F	0.796	0.73
97_H	115_I	0.795	0.72
557_A	561_E	0.792	0.72
587_A	727_A	0.792	0.72
369_K	504_H	0.791	0.72
551_C	555_A	0.790	0.72
738_N	741_D	0.788	0.72
597_T	608_T	0.788	0.72
408_M	411_A	0.787	0.72
76_K	91_E	0.785	0.72
532_R	584_Y	0.785	0.72
526_A	568_V	0.783	0.71
369_K	372_G	0.783	0.71
680_I	761_L	0.782	0.71
384_R	429_D	0.781	0.71
681_T	723_G	0.781	0.71
211_I	228_L	0.778	0.71
696_S	770_V	0.777	0.71
621_K	637_Q	0.775	0.71
699_V	768_A	0.773	0.70
714_I	738_N	0.772	0.70
42_M	78_M	0.772	0.70
575_D	751_E	0.772	0.70
595_V	710_R	0.769	0.70
72_Y	112_I	0.765	0.70
380_L	390_R	0.762	0.69
242_K	245_K	0.760	0.69
19_V	25_L	0.757	0.69
763_E	767_H	0.756	0.69
253_T	273_L	0.756	0.69
297_V	457_E	0.756	0.69
26_H	87_R	0.755	0.69
27_L	363_L	0.753	0.68
117_E	187_V	0.753	0.68
34_S	37_A	0.753	0.68
408_M	455_I	0.752	0.68
152_A	156_D	0.751	0.68
643_V	686_L	0.750	0.68
522_L	554_A	0.749	0.68
725_H	746_P	0.747	0.68
718_K	722_L	0.746	0.68
506_L	550_I	0.744	0.67
648_E	654_P	0.744	0.67
128_L	192_N	0.744	0.67
344_S	463_K	0.743	0.67
611_I	666_V	0.742	0.67
106_D	109_S	0.742	0.67
18_L	224_K	0.742	0.67
71_T	682_M	0.742	0.67
193_K	197_F	0.741	0.67
593_V	694_A	0.740	0.67
525_Q	751_E	0.739	0.67
403_R	607_D	0.739	0.67
648_E	653_E	0.739	0.67
739_E	742_I	0.738	0.67
235_I	240_G	0.737	0.67
132_L	167_V	0.737	0.67
164_A	194_V	0.735	0.66
353_A	488_N	0.734	0.66
78_M	86_I	0.733	0.66
664_I	682_M	0.733	0.66
129_M	160_P	0.732	0.66
19_V	90_V	0.732	0.66
711_V	764_V	0.732	0.66
339_Q	345_L	0.731	0.66
365_K	369_K	0.731	0.66
721_A	725_H	0.730	0.66
164_A	187_V	0.729	0.66
102_N	111_D	0.728	0.66
19_V	50_L	0.727	0.66
293_I	297_V	0.727	0.66
213_Q	265_V	0.727	0.66
161_G	186_D	0.727	0.66
681_T	764_V	0.726	0.66
252_L	297_V	0.725	0.65
161_G	187_V	0.725	0.65
377_R	449_S	0.723	0.65
532_R	585_G	0.723	0.65
52_T	67_F	0.722	0.65
596_V	729_L	0.721	0.65
294_D	298_A	0.721	0.65
295_W	347_G	0.721	0.65
588_E	708_R	0.720	0.65
314_A	333_L	0.720	0.65
215_V	227_Y	0.719	0.65
231_Q	237_K	0.719	0.65
319_D	333_L	0.719	0.65
341_L	514_G	0.718	0.65
259_A	297_V	0.717	0.65
681_T	701_M	0.716	0.64
526_A	569_T	0.716	0.64
486_I	542_S	0.716	0.64
567_T	571_K	0.714	0.64
225_E	229_R	0.713	0.64
592_Q	710_R	0.712	0.64
721_A	745_I	0.712	0.64
180_D	184_T	0.712	0.64
31_R	65_E	0.711	0.64
11_L	102_N	0.710	0.64
157_I	163_M	0.710	0.64
102_N	109_S	0.708	0.64
394_R	746_P	0.708	0.64
521_Q	571_K	0.708	0.64
352_L	467_I	0.708	0.64
660_Y	692_G	0.707	0.63
684_T	769_L	0.707	0.63
226_Y	233_K	0.706	0.63
210_K	234_A	0.705	0.63
284_A	288_V	0.704	0.63
745_I	750_R	0.704	0.63
77_Q	91_E	0.704	0.63
417_V	467_I	0.703	0.63
695_V	768_A	0.701	0.63
98_I	108_T	0.701	0.63
167_V	171_L	0.700	0.63
328_V	487_I	0.697	0.62
218_S	234_A	0.697	0.62
426_M	475_T	0.696	0.62
66_I	108_T	0.696	0.62
530_I	576_F	0.696	0.62
550_I	573_L	0.695	0.62
122_D	160_P	0.695	0.62
249_V	276_Y	0.692	0.62
295_W	405_I	0.692	0.62
596_V	643_V	0.692	0.62
251_T	254_E	0.692	0.62
189_D	192_N	0.689	0.61
268_T	456_E	0.688	0.61
206_E	210_K	0.687	0.61
307_D	339_Q	0.687	0.61
139_Y	205_L	0.686	0.61
51_A	54_Q	0.685	0.61
9_I	96_A	0.684	0.61
53_Q	65_E	0.683	0.61
406_Q	410_K	0.683	0.61
693_R	770_V	0.682	0.61
730_T	754_T	0.682	0.61
493_T	748_S	0.681	0.61
215_V	226_Y	0.677	0.60
694_A	770_V	0.677	0.60
378_I	418_F	0.676	0.60
223_Q	227_Y	0.674	0.60
225_E	235_I	0.673	0.60
370_S	531_I	0.673	0.60
22_T	162_R	0.673	0.60
652_I	657_H	0.673	0.60
75_I	88_V	0.673	0.60
574_Q	580_R	0.673	0.60
583_R	740_K	0.671	0.59
403_R	451_S	0.671	0.59
219_M	227_Y	0.669	0.59
557_A	563_R	0.669	0.59
652_I	655_D	0.669	0.59
72_Y	93_L	0.668	0.59
228_L	232_M	0.668	0.59
142_I	202_K	0.666	0.59
158_E	174_K	0.665	0.59
161_G	181_I	0.665	0.59
376_V	383_V	0.665	0.59
268_T	272_E	0.665	0.59
316_R	319_D	0.664	0.59
479_P	484_M	0.664	0.59
423_I	468_A	0.663	0.59
347_G	512_E	0.661	0.58
294_D	297_V	0.659	0.58
191_L	375_F	0.659	0.58
427_S	431_R	0.659	0.58
383_V	436_S	0.658	0.58
132_L	164_A	0.658	0.58
742_I	750_R	0.658	0.58
35_V	86_I	0.655	0.58
38_L	88_V	0.655	0.58
530_I	579_K	0.654	0.57
268_T	457_E	0.653	0.57
195_I	199_N	0.653	0.57
125_D	160_P	0.653	0.57
652_I	660_Y	0.652	0.57
30_G	61_P	0.652	0.57
88_V	150_T	0.651	0.57
326_E	746_P	0.650	0.57
272_E	282_S	0.650	0.57
335_Y	339_Q	0.649	0.57
271_K	298_A	0.648	0.57
407_G	410_K	0.647	0.57
683_A	765_L	0.647	0.57
232_M	236_Q	0.646	0.57
208_E	231_Q	0.646	0.57
224_K	649_E	0.644	0.56
262_P	302_T	0.644	0.56
256_I	266_K	0.642	0.56
733_I	755_F	0.640	0.56
587_A	729_L	0.640	0.56
236_Q	633_R	0.639	0.56
426_M	435_S	0.638	0.56
286_S	289_I	0.638	0.56
269_A	297_V	0.638	0.56
140_I	163_M	0.637	0.55
352_L	369_K	0.637	0.55
522_L	572_N	0.636	0.55
656_F	660_Y	0.634	0.55
525_Q	575_D	0.634	0.55
328_V	417_V	0.634	0.55
164_A	190_R	0.634	0.55
290_R	294_D	0.633	0.55
364_A	375_F	0.633	0.55
260_G	303_D	0.633	0.55
558_I	643_V	0.633	0.55
272_E	292_Y	0.632	0.55
231_Q	377_R	0.631	0.55
558_I	566_I	0.631	0.55
761_L	769_L	0.630	0.55
589_T	697_R	0.630	0.55
270_L	274_N	0.629	0.55
306_D	343_K	0.629	0.55
62_G	108_T	0.628	0.54
668_E	712_L	0.627	0.54
657_H	660_Y	0.626	0.54
69_V	179_Q	0.626	0.54
63_E	98_I	0.625	0.54
309_L	371_L	0.624	0.54
428_S	431_R	0.622	0.54
201_E	240_G	0.621	0.54
27_L	370_S	0.621	0.54
474_A	671_V	0.621	0.54
177_D	193_K	0.620	0.53
473_L	476_I	0.620	0.53
764_V	769_L	0.620	0.53
256_I	364_A	0.619	0.53
652_I	690_L	0.619	0.53
36_Q	298_A	0.618	0.53
8_S	102_N	0.617	0.53
181_I	197_F	0.616	0.53
327_K	744_D	0.616	0.53
317_L	378_I	0.616	0.53
28_D	364_A	0.616	0.53
137_D	155_T	0.615	0.53
644_R	661_D	0.615	0.53
315_G	326_E	0.615	0.53
261_M	302_T	0.615	0.53
207_I	417_V	0.614	0.53
518_S	521_Q	0.614	0.53
585_G	727_A	0.614	0.53
323_H	504_H	0.614	0.53
211_I	235_I	0.614	0.53
87_R	286_S	0.613	0.53
570_E	580_R	0.613	0.53
124_E	127_A	0.612	0.53
28_D	83_N	0.612	0.53
299_L	414_L	0.612	0.53
746_P	750_R	0.612	0.53
165_D	187_V	0.611	0.52
26_H	83_N	0.610	0.52
302_T	408_M	0.609	0.52
444_P	451_S	0.609	0.52
251_T	255_K	0.608	0.52
564_K	571_K	0.608	0.52
264_H	457_E	0.608	0.52
610_S	666_V	0.607	0.52
481_R	488_N	0.607	0.52
27_L	50_L	0.607	0.52
36_Q	106_D	0.607	0.52
261_M	270_L	0.606	0.52
139_Y	466_F	0.606	0.52
264_H	374_K	0.606	0.52
417_V	465_L	0.606	0.52
632_M	666_V	0.606	0.52
387_S	472_N	0.605	0.52
566_I	572_N	0.605	0.52
40_Q	109_S	0.605	0.52
336_L	371_L	0.605	0.52
617_P	659_K	0.605	0.52
584_Y	727_A	0.603	0.51
617_P	648_E	0.603	0.51
441_V	461_L	0.603	0.51
36_Q	40_Q	0.603	0.51
717_L	756_I	0.602	0.51
451_S	708_R	0.601	0.51
37_A	689_A	0.601	0.51
241_D	404_I	0.600	0.51
265_V	296_L	0.599	0.51
234_A	237_K	0.598	0.51
128_L	132_L	0.598	0.51
400_M	407_G	0.598	0.51
63_E	104_H	0.596	0.51
647_T	687_V	0.595	0.51
265_V	269_A	0.595	0.51
67_F	179_Q	0.595	0.51
163_M	509_Q	0.594	0.50
585_G	668_E	0.594	0.50
364_A	495_I	0.594	0.50
231_Q	239_L	0.593	0.50
427_S	435_S	0.593	0.50
126_E	130_R	0.593	0.50
152_A	582_F	0.593	0.50
183_E	662_I	0.593	0.50
668_E	671_V	0.592	0.50
321_E	504_H	0.591	0.50
72_Y	114_L	0.591	0.50
681_T	711_V	0.590	0.50
400_M	603_T	0.590	0.50
592_Q	708_R	0.590	0.50
136_F	140_I	0.589	0.50
495_I	725_H	0.588	0.50
16_G	26_H	0.588	0.50
388_E	609_L	0.587	0.50
579_K	740_K	0.587	0.50
276_Y	286_S	0.587	0.50
684_T	701_M	0.587	0.50
54_Q	65_E	0.587	0.50
138_Q	340_K	0.585	0.49
218_S	230_E	0.584	0.49
333_L	336_L	0.584	0.49
602_T	632_M	0.584	0.49
192_N	353_A	0.582	0.49
349_I	622_L	0.582	0.49
414_L	504_H	0.581	0.49
123_T	126_E	0.581	0.49
510_I	513_H	0.580	0.49
116_H	185_A	0.580	0.49
15_R	351_C	0.579	0.49
348_P	722_L	0.579	0.49
207_I	210_K	0.578	0.49
348_P	718_K	0.578	0.49
506_L	510_I	0.578	0.49
371_L	458_T	0.577	0.48
506_L	526_A	0.577	0.48
31_R	55_D	0.577	0.48
523_R	572_N	0.577	0.48
95_R	178_K	0.577	0.48
9_I	112_I	0.577	0.48
119_D	159_E	0.577	0.48
148_A	151_Y	0.577	0.48
266_K	297_V	0.576	0.48
387_S	577_I	0.576	0.48
311_L	333_L	0.576	0.48
386_E	441_V	0.576	0.48
638_A	641_S	0.576	0.48
164_A	181_I	0.576	0.48
467_I	518_S	0.575	0.48
101_Y	110_V	0.575	0.48
48_I	51_A	0.575	0.48
72_Y	296_L	0.575	0.48
642_Y	650_L	0.575	0.48
91_E	272_E	0.575	0.48
229_R	458_T	0.575	0.48
143_S	146_I	0.574	0.48
268_T	668_E	0.574	0.48
24_V	166_I	0.573	0.48
116_H	316_R	0.573	0.48
257_E	498_L	0.573	0.48
53_Q	58_I	0.573	0.48
491_G	722_L	0.572	0.48
189_D	193_K	0.572	0.48
522_L	581_I	0.572	0.48
192_N	196_D	0.571	0.48
284_A	431_R	0.571	0.48
92_G	205_L	0.571	0.48
387_S	400_M	0.569	0.47
491_G	538_A	0.568	0.47
588_E	597_T	0.568	0.47
601_Y	632_M	0.568	0.47
42_M	46_H	0.568	0.47
63_E	100_K	0.567	0.47
574_Q	579_K	0.565	0.47
125_D	191_L	0.565	0.47
597_T	726_R	0.565	0.47
255_K	258_E	0.565	0.47
99_V	103_E	0.565	0.47
66_I	101_Y	0.564	0.47
303_D	412_G	0.564	0.47
185_A	190_R	0.564	0.47
235_I	238_E	0.564	0.47
358_V	495_I	0.564	0.47
579_K	741_D	0.563	0.47
16_G	23_M	0.563	0.47
321_E	509_Q	0.562	0.47
407_G	451_S	0.562	0.47
24_V	89_L	0.562	0.47
13_P	66_I	0.562	0.47
341_L	458_T	0.561	0.47
30_G	358_V	0.561	0.47
335_Y	348_P	0.561	0.47
640_F	686_L	0.560	0.46
733_I	756_I	0.560	0.46
219_M	223_Q	0.560	0.46
531_I	543_L	0.559	0.46
272_E	419_L	0.558	0.46
643_V	652_I	0.558	0.46
736_K	757_L	0.558	0.46
159_E	162_R	0.558	0.46
558_I	561_E	0.558	0.46
449_S	458_T	0.557	0.46
77_Q	80_K	0.557	0.46
525_Q	567_T	0.557	0.46
595_V	608_T	0.557	0.46
291_N	413_K	0.557	0.46
132_L	586_Q	0.555	0.46
27_L	90_V	0.555	0.46
27_L	88_V	0.555	0.46
285_E	294_D	0.555	0.46
557_A	573_L	0.555	0.46
470_A	681_T	0.554	0.46
56_I	88_V	0.554	0.46
400_M	413_K	0.554	0.46
433_D	436_S	0.554	0.46
245_K	249_V	0.553	0.46
523_R	575_D	0.552	0.45
519_N	559_V	0.552	0.45
506_L	551_C	0.552	0.45
135_H	138_Q	0.552	0.45
451_S	455_I	0.551	0.45
47_M	72_Y	0.551	0.45
638_A	646_K	0.550	0.45
144_K	148_A	0.550	0.45
693_R	766_E	0.550	0.45
529_D	574_Q	0.550	0.45
165_D	186_D	0.549	0.45
54_Q	67_F	0.549	0.45
305_T	415_N	0.549	0.45
279_I	284_A	0.549	0.45
319_D	503_D	0.549	0.45
36_Q	39_E	0.549	0.45
652_I	656_F	0.548	0.45
122_D	125_D	0.548	0.45
192_N	214_R	0.548	0.45
71_T	281_S	0.548	0.45
325_L	489_I	0.547	0.45
93_L	538_A	0.547	0.45
139_Y	143_S	0.547	0.45
491_G	726_R	0.547	0.45
488_N	671_V	0.546	0.45
88_V	583_R	0.546	0.45
228_L	238_E	0.546	0.45
702_T	715_G	0.545	0.45
121_K	502_K	0.545	0.45
179_Q	201_E	0.545	0.45
228_L	240_G	0.544	0.45
127_A	201_E	0.543	0.44
681_T	695_V	0.543	0.44
389_I	437_A	0.542	0.44
17_L	25_L	0.542	0.44
133_L	137_D	0.541	0.44
26_H	77_Q	0.540	0.44
591_D	769_L	0.540	0.44
438_M	468_A	0.540	0.44
373_R	415_N	0.540	0.44
495_I	499_E	0.540	0.44
252_L	293_I	0.539	0.44
317_L	370_S	0.539	0.44
261_M	266_K	0.539	0.44
103_E	107_Y	0.539	0.44
408_M	412_G	0.539	0.44
510_I	518_S	0.539	0.44
178_K	195_I	0.538	0.44
312_K	315_G	0.538	0.44
504_H	508_K	0.538	0.44
325_L	387_S	0.537	0.44
287_S	397_V	0.537	0.44
579_K	744_D	0.537	0.44
615_L	656_F	0.537	0.44
293_I	574_Q	0.537	0.44
390_R	535_T	0.537	0.44
544_E	547_L	0.536	0.44
263_D	575_D	0.536	0.44
262_P	457_E	0.536	0.44
306_D	415_N	0.536	0.44
533_Y	584_Y	0.536	0.44
636_A	682_M	0.535	0.43
139_Y	145_K	0.535	0.43
427_S	430_F	0.535	0.43
744_D	750_R	0.535	0.43
554_A	572_N	0.535	0.43
200_N	311_L	0.535	0.43
129_M	191_L	0.534	0.43
274_N	515_L	0.533	0.43
636_A	666_V	0.533	0.43
20_Y	175_L	0.533	0.43
523_R	751_E	0.532	0.43
77_Q	89_L	0.531	0.43
125_D	129_M	0.531	0.43
495_I	528_L	0.531	0.43
744_D	752_G	0.531	0.43
306_D	511_K	0.530	0.43
363_L	388_E	0.530	0.43
291_N	295_W	0.530	0.43
331_R	334_E	0.530	0.43
269_A	350_L	0.530	0.43
178_K	272_E	0.530	0.43
128_L	191_L	0.530	0.43
520_L	555_A	0.529	0.43
156_D	224_K	0.529	0.43
195_I	275_R	0.529	0.43
550_I	554_A	0.529	0.43
230_E	237_K	0.528	0.43
488_N	603_T	0.527	0.43
131_T	135_H	0.526	0.42
39_E	137_D	0.526	0.42
181_I	184_T	0.526	0.42
624_L	640_F	0.525	0.42
12_L	18_L	0.525	0.42
400_M	455_I	0.525	0.42
126_E	174_K	0.525	0.42
341_L	551_C	0.525	0.42
332_I	489_I	0.524	0.42
257_E	260_G	0.524	0.42
23_M	221_R	0.524	0.42
303_D	367_I	0.524	0.42
568_V	576_F	0.524	0.42
128_L	164_A	0.524	0.42
762_D	766_E	0.524	0.42
69_V	97_H	0.523	0.42
122_D	126_E	0.523	0.42
57_S	408_M	0.523	0.42
20_Y	181_I	0.523	0.42
491_G	597_T	0.523	0.42
353_A	470_A	0.522	0.42
601_Y	604_V	0.522	0.42
586_Q	737_D	0.521	0.42
226_Y	238_E	0.520	0.42
320_E	372_G	0.520	0.42
599_L	721_A	0.520	0.42
268_T	271_K	0.520	0.42
488_N	491_G	0.520	0.42
265_V	527_I	0.520	0.42
633_R	657_H	0.519	0.42
604_V	700_G	0.519	0.42
655_D	658_E	0.519	0.42
591_D	698_E	0.519	0.42
303_D	511_K	0.519	0.42
211_I	231_Q	0.519	0.42
692_G	765_L	0.518	0.42
26_H	89_L	0.518	0.42
29_V	33_K	0.518	0.42
333_L	586_Q	0.517	0.41
689_A	708_R	0.517	0.41
309_L	313_E	0.517	0.41
144_K	611_I	0.517	0.41
358_V	375_F	0.517	0.41
620_G	644_R	0.517	0.41
664_I	681_T	0.517	0.41
85_T	178_K	0.516	0.41
489_I	624_L	0.516	0.41
17_L	87_R	0.516	0.41
82_P	149_E	0.516	0.41
649_E	766_E	0.516	0.41
463_K	617_P	0.516	0.41
11_L	98_I	0.515	0.41
389_I	453_H	0.515	0.41
50_L	88_V	0.515	0.41
687_V	693_R	0.515	0.41
600_A	674_D	0.514	0.41
208_E	268_T	0.514	0.41
358_V	363_L	0.514	0.41
332_I	465_L	0.514	0.41
364_A	601_Y	0.514	0.41
110_V	489_I	0.513	0.41
231_Q	235_I	0.513	0.41
508_K	548_A	0.513	0.41
525_Q	529_D	0.512	0.41
524_D	527_I	0.512	0.41
181_I	193_K	0.512	0.41
338_V	514_G	0.512	0.41
597_T	697_R	0.511	0.41
717_L	725_H	0.511	0.41
28_D	76_K	0.509	0.40
93_L	550_I	0.509	0.40
593_V	691_T	0.508	0.40
572_N	577_I	0.508	0.40
37_A	53_Q	0.508	0.40
682_M	696_S	0.508	0.40
288_V	453_H	0.507	0.40
547_L	570_E	0.507	0.40
133_L	143_S	0.507	0.40
15_R	55_D	0.507	0.40
509_Q	514_G	0.507	0.40
554_A	568_V	0.507	0.40
282_S	286_S	0.507	0.40
721_A	733_I	0.506	0.40
593_V	689_A	0.506	0.40
647_T	650_L	0.506	0.40
55_D	160_P	0.506	0.40
78_M	192_N	0.506	0.40
695_V	769_L	0.505	0.40
257_E	263_D	0.505	0.40
743_E	750_R	0.505	0.40
129_M	132_L	0.505	0.40
189_D	569_T	0.504	0.40
112_I	258_E	0.504	0.40
233_K	455_I	0.504	0.40
275_R	294_D	0.503	0.40
312_K	561_E	0.503	0.40
285_E	289_I	0.503	0.40
366_S	369_K	0.503	0.40
262_P	408_M	0.503	0.40
664_I	705_I	0.503	0.40
62_G	100_K	0.502	0.40
517_K	521_Q	0.502	0.40
305_T	371_L	0.502	0.40
128_L	195_I	0.502	0.40
640_F	644_R	0.502	0.40
750_R	757_L	0.502	0.40
379_S	547_L	0.501	0.40
435_S	616_S	0.501	0.40
601_Y	674_D	0.501	0.40
33_K	105_E	0.501	0.40
62_G	68_T	0.501	0.40
227_Y	234_A	0.501	0.40
417_V	529_D	0.501	0.40
201_E	553_K	0.501	0.40
320_E	352_L	0.500	0.39
390_R	420_L	0.500	0.39
330_E	642_Y	0.500	0.39
211_I	239_L	0.500	0.39
102_N	105_E	0.500	0.39
614_S	640_F	0.500	0.39

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3m6aA	3	0.6408	100	0.552	Contact Map
3k1jA	4	0.5736	100	0.728	Contact Map
4fwgA	3	0.6395	100	0.783	Contact Map
3wu4A	3	0.2403	100	0.83	Contact Map
2x36A	3	0.2442	100	0.831	Contact Map
3ljcA	1	0.3088	100	0.845	Contact Map
1xhkA	2	0.23	100	0.846	Contact Map
1z0wA	3	0.239	100	0.849	Contact Map
4gitA	2	0.1189	100	0.856	Contact Map
1qvrA	3	0.6408	100	0.865	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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