GREMLIN Database
ATPF - ATP synthase subunit b
UniProt: P37814 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 170 (152)
Sequences: 4056 (2863)
Seq/√Len: 232.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_N45_Q2.9261.00
51_A55_T2.5741.00
59_E63_E2.5321.00
44_K48_D2.3201.00
84_T88_N2.2601.00
58_E62_K2.2421.00
151_D154_A2.2361.00
48_D52_G2.1441.00
104_A108_S2.1161.00
99_E103_A2.1041.00
52_G56_S1.9961.00
68_I72_R1.8781.00
66_Q70_E1.8711.00
103_A107_E1.8491.00
55_T59_E1.8221.00
109_E113_E1.7841.00
120_V124_E1.7601.00
113_E117_T1.7441.00
25_L29_A1.7171.00
108_S111_L1.6891.00
44_K47_E1.6671.00
94_E98_E1.6591.00
29_A33_K1.6251.00
138_S142_A1.6231.00
73_V77_E1.6091.00
69_E72_R1.6031.00
69_E73_V1.5651.00
112_K116_R1.5591.00
98_E102_Q1.5571.00
157_K161_D1.5451.00
81_E84_T1.5321.00
154_A157_K1.5061.00
70_E74_L1.4991.00
62_K66_Q1.4851.00
148_K154_A1.4771.00
96_Q99_E1.4451.00
77_E81_E1.4441.00
87_E90_K1.4241.00
47_E51_A1.4161.00
87_E91_K1.4021.00
55_T58_E1.4001.00
91_K95_K1.3991.00
123_K127_V1.3891.00
38_P41_N1.3861.00
102_Q105_R1.3781.00
102_Q106_A1.3641.00
71_Q74_L1.3641.00
97_K100_I1.3571.00
153_Q156_E1.3531.00
45_Q49_H1.3511.00
29_A32_K1.3461.00
105_R109_E1.3421.00
77_E80_Q1.3341.00
62_K65_Q1.3341.00
152_E156_E1.3201.00
65_Q69_E1.2591.00
49_H53_E1.2581.00
106_A109_E1.2561.00
56_S60_K1.2461.00
122_E125_Q1.2291.00
97_K101_I1.2171.00
138_S141_I1.2171.00
72_R76_K1.1741.00
115_A119_I1.1711.00
65_Q68_I1.1591.00
61_N65_Q1.1501.00
106_A110_R1.1401.00
129_A133_Q1.1361.00
111_L119_I1.1301.00
45_Q48_D1.1101.00
73_V76_K1.1091.00
88_N92_L1.1021.00
156_E160_Q1.0931.00
94_E97_K1.0891.00
28_L32_K1.0771.00
96_Q101_I1.0501.00
103_A106_A1.0461.00
90_K94_E1.0401.00
161_D165_E1.0361.00
74_L77_E1.0331.00
95_K99_E1.0321.00
74_L79_R1.0241.00
110_R114_A1.0231.00
63_E66_Q1.0121.00
149_E155_Q1.0031.00
83_Q87_E1.0021.00
124_E128_S1.0021.00
67_L70_E0.9971.00
80_Q83_Q0.9941.00
16_D20_Q0.9901.00
121_K125_Q0.9851.00
16_D19_F0.9821.00
67_L71_Q0.9751.00
70_E73_V0.9721.00
153_Q157_K0.9721.00
66_Q69_E0.9711.00
116_R120_V0.9661.00
143_S147_E0.9651.00
101_I105_R0.9641.00
64_A68_I0.9531.00
119_I126_A0.9501.00
99_E102_Q0.9471.00
96_Q100_I0.9441.00
17_I20_Q0.9441.00
134_V138_S0.9321.00
53_E61_N0.9301.00
92_L95_K0.9251.00
116_R122_E0.9171.00
78_A82_S0.9131.00
120_V123_K0.9091.00
114_A117_T0.9030.99
59_E62_K0.8980.99
33_K37_G0.8980.99
93_G97_K0.8910.99
91_K94_E0.8860.99
48_D51_A0.8620.99
80_Q84_T0.8560.99
35_A38_P0.8430.99
32_K37_G0.8310.99
140_M144_K0.8300.99
63_E68_I0.8230.99
86_I90_K0.8230.99
113_E116_R0.8100.99
40_L43_M0.8020.99
108_S112_K0.8000.99
20_Q23_A0.7980.99
82_S86_I0.7950.99
148_K161_D0.7900.99
89_A93_G0.7830.99
15_G18_L0.7710.98
136_S140_M0.7710.98
32_K36_L0.7680.98
31_L35_A0.7620.98
93_G100_I0.7600.98
118_E122_E0.7550.98
117_T120_V0.7530.98
150_L155_Q0.7530.98
107_E111_L0.7490.98
36_L40_L0.7490.98
58_E61_N0.7420.98
125_Q129_A0.7410.98
24_M28_L0.7410.98
119_I130_L0.7410.98
57_A64_A0.7350.98
20_Q28_L0.7350.98
56_S59_E0.7330.98
68_I71_Q0.7270.98
100_I104_A0.7170.97
82_S85_L0.7130.97
128_S131_R0.7130.97
130_L134_V0.7090.97
150_L154_A0.7080.97
76_K80_Q0.7020.97
23_A26_I0.6990.97
107_E110_R0.6980.97
75_L79_R0.6970.97
133_Q136_S0.6950.97
81_E85_L0.6880.97
159_I163_L0.6840.97
112_K118_E0.6840.97
140_M143_S0.6790.96
42_I45_Q0.6720.96
15_G19_F0.6680.96
43_M47_E0.6660.96
144_K148_K0.6640.96
124_E127_V0.6620.96
67_L72_R0.6580.96
16_D28_L0.6560.96
49_H52_G0.6490.95
144_K147_E0.6430.95
19_F23_A0.6420.95
20_Q24_M0.6370.95
160_Q164_K0.6370.95
40_L44_K0.6360.95
62_K69_E0.6350.95
30_L34_Y0.6320.95
128_S132_E0.6300.95
63_E67_L0.6250.94
20_Q38_P0.6100.94
109_E112_K0.6090.94
127_V130_L0.6080.94
28_L36_L0.6060.94
60_K64_A0.6040.93
88_N91_K0.6020.93
32_K35_A0.5970.93
52_G59_E0.5930.93
19_F26_I0.5820.92
134_V137_L0.5820.92
117_T121_K0.5810.92
115_A158_L0.5800.92
22_L26_I0.5790.92
74_L81_E0.5780.92
125_Q128_S0.5770.92
79_R82_S0.5770.92
31_L36_L0.5760.92
48_D56_S0.5750.92
161_D164_K0.5730.91
60_K63_E0.5680.91
53_E56_S0.5640.91
19_F22_L0.5610.91
100_I108_S0.5520.90
121_K124_E0.5500.90
50_I53_E0.5500.90
23_A36_L0.5500.90
95_K98_E0.5410.89
92_L135_A0.5380.89
88_N95_K0.5380.89
79_R83_Q0.5370.89
142_A146_I0.5370.89
39_L43_M0.5260.88
86_I89_A0.5250.88
137_L144_K0.5250.88
54_I58_E0.5240.87
27_L31_L0.5230.87
98_E101_I0.5220.87
18_L22_L0.5220.87
150_L159_I0.5190.87
141_I162_Y0.5170.87
50_I54_I0.5120.86
133_Q137_L0.5100.86
101_I107_E0.5090.86
129_A132_E0.5090.86
118_E125_Q0.5090.86
32_K41_N0.5070.86
93_G103_A0.5030.85
119_I123_K0.5030.85
34_Y38_P0.5020.85
141_I155_Q0.5000.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2dm9A 2 0.2176 98.3 0.766 Contact Map
1b9uA 1 0.2 98 0.787 Contact Map
2khkA 1 0.3118 97.9 0.789 Contact Map
1l2pA 1 0.3588 97.8 0.793 Contact Map
3v6iA 1 0.6706 97.8 0.797 Contact Map
2clyA 1 0.5941 96.7 0.829 Contact Map
4efaE 1 0.7 92.9 0.864 Contact Map
4efaG 1 0.5412 83.8 0.886 Contact Map
2oarA 7 0.4118 77.5 0.893 Contact Map
3v6iB 1 0.5941 71.7 0.898 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0067 seconds.