GREMLIN Database
CHEV - Chemotaxis protein CheV
UniProt: P37599 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 303 (281)
Sequences: 29279 (23827)
Seq/√Len: 1421.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
203_A229_I3.2281.00
187_M204_S3.0851.00
140_I152_I2.6661.00
216_M253_N2.6461.00
144_D147_K2.6381.00
207_N240_K2.6021.00
104_V141_F2.5831.00
209_K240_K2.5721.00
130_T134_K2.4901.00
206_E210_E2.4791.00
234_T246_L2.4721.00
93_N150_Y2.4551.00
191_Q204_S2.4091.00
100_H103_S2.3911.00
176_K200_N2.3641.00
180_V211_A2.3181.00
176_K203_A2.3041.00
283_E296_K2.2701.00
89_V154_S2.2321.00
8_I12_S2.2071.00
187_M206_E2.2011.00
242_D245_R2.1901.00
91_E150_Y2.1751.00
197_A294_I2.1711.00
89_V152_I2.1251.00
247_T261_V2.0751.00
69_I95_R2.0571.00
87_Y154_S2.0551.00
251_K282_D2.0401.00
249_L252_E2.0371.00
203_A214_Y1.9821.00
50_H136_E1.9321.00
205_F214_Y1.9161.00
263_I281_A1.8511.00
91_E152_I1.8391.00
247_T281_A1.8381.00
100_H145_Y1.8321.00
99_F103_S1.7931.00
103_S106_Q1.7541.00
142_L150_Y1.7491.00
129_L139_M1.7371.00
191_Q195_K1.7341.00
241_M249_L1.7171.00
16_E20_V1.7131.00
8_I11_D1.7111.00
101_V104_V1.7051.00
237_E267_L1.6521.00
283_E299_T1.6181.00
207_N210_E1.6141.00
172_R199_Y1.5911.00
134_K138_L1.5891.00
209_K213_E1.5811.00
178_I205_F1.5691.00
212_Y246_L1.5231.00
175_K199_Y1.4961.00
106_Q112_W1.4891.00
203_A227_K1.4881.00
262_M296_K1.4681.00
215_I250_L1.4671.00
296_K299_T1.4671.00
274_H278_V1.4571.00
141_F151_D1.4561.00
254_P257_S1.4511.00
241_M245_R1.4481.00
289_E292_D1.4461.00
214_Y217_N1.4141.00
109_R112_W1.4051.00
212_Y249_L1.3991.00
179_I190_L1.3961.00
236_I244_H1.3951.00
73_S95_R1.3951.00
214_Y229_I1.3911.00
234_T247_T1.3901.00
99_F107_I1.3841.00
236_I263_I1.3751.00
254_P258_D1.3681.00
104_V143_P1.3591.00
177_L231_M1.3581.00
76_G93_N1.3551.00
208_G241_M1.3491.00
148_I154_S1.3411.00
249_L253_N1.3411.00
45_V196_E1.3401.00
231_M297_V1.3391.00
193_E290_I1.3321.00
208_G246_L1.3311.00
80_E89_V1.3241.00
142_L152_I1.3081.00
177_L199_Y1.2971.00
245_R249_L1.2911.00
176_K230_D1.2881.00
57_G129_L1.2821.00
94_K98_V1.2801.00
90_T153_E1.2731.00
181_E187_M1.2701.00
176_K227_K1.2591.00
50_H55_V1.2391.00
133_I153_E1.2381.00
57_G132_I1.2211.00
57_G133_I1.2181.00
10_L13_G1.2181.00
244_H276_G1.2171.00
78_E91_E1.2101.00
138_L154_S1.2041.00
232_I250_L1.1961.00
108_H139_M1.1961.00
232_I259_V1.1951.00
15_N19_I1.1901.00
103_S114_A1.1871.00
213_E217_N1.1781.00
45_V290_I1.1681.00
272_L275_R1.1621.00
245_R248_K1.1611.00
149_I154_S1.1471.00
292_D296_K1.1421.00
179_I202_I1.1311.00
58_M90_T1.1241.00
273_R277_E1.1211.00
184_P187_M1.1131.00
176_K229_I1.1121.00
57_G153_E1.1091.00
106_Q109_R1.1081.00
69_I75_F1.1021.00
175_K230_D1.0941.00
270_D274_H1.0871.00
209_K241_M1.0861.00
143_P147_K1.0861.00
213_E216_M1.0861.00
12_S15_N1.0851.00
253_N256_S1.0831.00
292_D295_K1.0821.00
267_L272_L1.0801.00
35_K39_I1.0791.00
188_R191_Q1.0631.00
205_F211_A1.0621.00
110_V131_G1.0611.00
9_L13_G1.0601.00
236_I276_G1.0581.00
210_E213_E1.0551.00
174_D200_N1.0481.00
39_I189_L1.0461.00
269_T272_L1.0421.00
118_P121_L1.0361.00
212_Y241_M1.0321.00
55_V90_T1.0311.00
35_K185_L1.0211.00
178_I211_A1.0171.00
265_S284_Q1.0151.00
69_I73_S1.0101.00
107_I141_F1.0091.00
234_T263_I1.0091.00
129_L133_I1.0041.00
172_R175_K1.0041.00
191_Q202_I1.0021.00
40_I44_E0.9961.00
276_G284_Q0.9961.00
184_P206_E0.9941.00
15_N18_E0.9851.00
41_Q290_I0.9851.00
210_E214_Y0.9851.00
73_S93_N0.9801.00
215_I259_V0.9771.00
114_A118_P0.9721.00
54_H132_I0.9691.00
268_I286_S0.9681.00
180_V246_L0.9661.00
256_S259_V0.9651.00
232_I261_V0.9641.00
211_A246_L0.9511.00
34_M186_L0.9491.00
190_L264_F0.9481.00
290_I294_I0.9441.00
174_D199_Y0.9401.00
215_I256_S0.9331.00
233_I264_F0.9311.00
270_D273_R0.9301.00
74_F95_R0.9261.00
70_S74_F0.9261.00
133_I139_M0.9211.00
143_P149_I0.9101.00
276_G280_G0.9091.00
69_I72_F0.9041.00
130_T138_L0.9031.00
140_I154_S0.9011.00
12_S16_E0.8961.00
99_F104_V0.8951.00
76_G91_E0.8921.00
205_F210_E0.8921.00
236_I281_A0.8881.00
20_V110_V0.8871.00
51_S54_H0.8871.00
184_P188_R0.8861.00
13_G17_L0.8801.00
101_V144_D0.8751.00
215_I254_P0.8631.00
103_S112_W0.8581.00
244_H275_R0.8571.00
62_R75_F0.8551.00
276_G281_A0.8531.00
41_Q289_E0.8481.00
200_N203_A0.8471.00
182_D238_M0.8401.00
215_I253_N0.8381.00
254_P259_V0.8381.00
131_G135_L0.8371.00
38_E189_L0.8371.00
214_Y227_K0.8341.00
143_P146_E0.8281.00
180_V208_G0.8281.00
9_L12_S0.8281.00
248_K252_E0.8271.00
178_I229_I0.8241.00
182_D235_D0.8221.00
246_L250_L0.8191.00
294_I298_D0.8091.00
275_R278_V0.8051.00
99_F105_S0.8031.00
94_K148_I0.8031.00
216_M249_L0.8021.00
181_E238_M0.8021.00
234_T261_V0.8011.00
196_E290_I0.8001.00
233_I293_L0.7981.00
262_M283_E0.7941.00
188_R192_D0.7941.00
131_G134_K0.7941.00
56_E132_I0.7921.00
46_T196_E0.7891.00
99_F141_F0.7881.00
197_A290_I0.7861.00
13_G16_E0.7831.00
211_A215_I0.7811.00
113_E121_L0.7801.00
192_D195_K0.7791.00
61_L153_E0.7761.00
58_M62_R0.7641.00
186_L189_L0.7621.00
195_K202_I0.7601.00
180_V238_M0.7601.00
180_V234_T0.7591.00
215_I232_I0.7461.00
97_I121_L0.7441.00
180_V232_I0.7411.00
89_V140_I0.7371.00
248_K279_V0.7371.00
183_S186_L0.7371.00
48_V86_K0.7361.00
36_V40_I0.7341.00
176_K228_Q0.7321.00
87_Y138_L0.7301.00
291_S295_K0.7291.00
180_V205_F0.7281.00
20_V24_V0.7281.00
295_K299_T0.7271.00
241_M246_L0.7251.00
212_Y216_M0.7241.00
70_S97_I0.7241.00
260_P282_D0.7231.00
244_H248_K0.7201.00
199_Y202_I0.7191.00
271_D274_H0.7131.00
108_H141_F0.7131.00
212_Y215_I0.7121.00
27_N31_I0.7091.00
234_T250_L0.7081.00
209_K249_L0.7071.00
208_G212_Y0.7061.00
14_T18_E0.7051.00
210_E240_K0.7041.00
247_T263_I0.7031.00
251_K259_V0.6991.00
182_D239_P0.6991.00
175_K298_D0.6991.00
61_L92_F0.6991.00
244_H263_I0.6961.00
104_V142_L0.6951.00
199_Y294_I0.6901.00
189_L193_E0.6841.00
24_V110_V0.6841.00
238_M243_G0.6831.00
68_V113_E0.6831.00
258_D282_D0.6821.00
277_E280_G0.6811.00
233_I262_M0.6801.00
61_L139_M0.6801.00
217_N227_K0.6791.00
238_M246_L0.6791.00
100_H114_A0.6791.00
194_L297_V0.6781.00
21_K25_G0.6781.00
188_R204_S0.6771.00
41_Q45_V0.6711.00
99_F149_I0.6691.00
132_I136_E0.6691.00
232_I246_L0.6641.00
49_P158_V0.6631.00
87_Y156_S0.6631.00
273_R284_Q0.6611.00
60_K63_G0.6591.00
38_E42_P0.6591.00
11_D15_N0.6591.00
59_I63_G0.6561.00
177_L194_L0.6561.00
110_V127_R0.6541.00
200_N227_K0.6521.00
133_I155_D0.6501.00
28_A31_I0.6501.00
189_L192_D0.6481.00
240_K246_L0.6481.00
31_I38_E0.6451.00
236_I267_L0.6441.00
207_N238_M0.6411.00
231_M262_M0.6411.00
11_D14_T0.6411.00
277_E281_A0.6401.00
261_V281_A0.6371.00
35_K38_E0.6371.00
236_I242_D0.6341.00
78_E93_N0.6321.00
157_G160_T0.6281.00
247_T279_V0.6271.00
275_R279_V0.6271.00
20_V116_E0.6261.00
182_D265_S0.6241.00
244_H279_V0.6231.00
151_D154_S0.6221.00
61_L129_L0.6191.00
156_S159_D0.6151.00
107_I127_R0.6131.00
78_E89_V0.6121.00
215_I229_I0.6121.00
285_I296_K0.6101.00
208_G239_P0.6091.00
271_D275_R0.6081.00
208_G238_M0.6081.00
116_E119_T0.6071.00
179_I204_S0.6061.00
29_F32_N0.6061.00
194_L199_Y0.6061.00
115_I118_P0.6051.00
14_T17_L0.6031.00
79_P86_K0.6021.00
187_M191_Q0.6011.00
205_F208_G0.6001.00
37_R40_I0.6001.00
250_L256_S0.5991.00
115_I120_S0.5981.00
42_P192_D0.5921.00
235_D287_K0.5921.00
158_V161_Y0.5911.00
248_K275_R0.5911.00
113_E122_N0.5891.00
263_I276_G0.5851.00
182_D243_G0.5841.00
190_L293_L0.5831.00
182_D287_K0.5831.00
273_R283_E0.5821.00
19_I23_G0.5801.00
99_F143_P0.5791.00
179_I187_M0.5791.00
31_I35_K0.5791.00
39_I42_P0.5781.00
184_P204_S0.5781.00
115_I119_T0.5771.00
28_A32_N0.5751.00
31_I34_M0.5741.00
182_D266_S0.5711.00
82_S85_E0.5681.00
192_D196_E0.5651.00
63_G67_P0.5641.00
40_I43_V0.5611.00
208_G243_G0.5611.00
22_F25_G0.5601.00
173_T199_Y0.5601.00
177_L202_I0.5581.00
81_G86_K0.5581.00
190_L193_E0.5551.00
100_H104_V0.5541.00
72_F75_F0.5521.00
27_N35_K0.5511.00
88_I157_G0.5501.00
27_N30_G0.5481.00
178_I215_I0.5471.00
9_L16_E0.5471.00
251_K254_P0.5461.00
274_H277_E0.5441.00
127_R131_G0.5431.00
185_L188_R0.5411.00
17_L20_V0.5401.00
41_Q44_E0.5371.00
26_E31_I0.5371.00
37_R41_Q0.5361.00
10_L14_T0.5361.00
55_V155_D0.5351.00
64_E68_V0.5341.00
18_E22_F0.5301.00
48_V88_I0.5291.00
71_L74_F0.5281.00
251_K261_V0.5271.00
83_K86_K0.5261.00
101_V105_S0.5261.00
180_V207_N0.5241.00
199_Y298_D0.5231.00
27_N33_V0.5211.00
104_V107_I0.5191.00
97_I149_I0.5161.00
56_E128_H0.5161.00
133_I138_L0.5151.00
91_E142_L0.5141.00
29_F33_V0.5131.00
60_K123_Q0.5121.00
267_L276_G0.5121.00
234_T238_M0.5081.00
27_N32_N0.5061.00
67_P113_E0.5061.00
198_G202_I0.5061.00
172_R298_D0.5041.00
148_I151_D0.5021.00
44_E47_S0.5011.00
126_E129_L0.5001.00
253_N257_S0.5001.00
238_M241_M0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3mm4A 1 0.4521 99.9 0.59 Contact Map
3breA 4 0.4125 99.9 0.627 Contact Map
1w25A 2 0.396 99.9 0.628 Contact Map
3r0jA 2 0.396 99.9 0.635 Contact Map
3dzdA 2 0.3861 99.9 0.636 Contact Map
4g97A 1 0.7393 99.9 0.636 Contact Map
3eq2A 2 0.3927 99.9 0.637 Contact Map
3n0rA 1 0.7756 99.9 0.641 Contact Map
3rqiA 2 0.3861 99.9 0.65 Contact Map
4l4uA 2 0.4125 99.9 0.651 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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