TILS - BACSU - GREMLIN Contacts

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TILS - tRNA(Ile)-lysidine synthase

UniProt:	P37563	Sequences: MKSVKDFLNKHNLTLKGATIIVGVSGGPDSMALLHALHTLCGRSANVIAAHVDHRFRGAESEEDMRFVQAYCKAEQLVCETAQINVTAYAQEKGLNKQAAARDCRYQFFEEIMSKHQADYLALAHHGDDQVETMLMKLAKGTLGTGLAGMQPVRRFGTGRIIRPFLTITKEEILHYCHENGLSYRTDESNAKDDYTRNRFRKTVLPFLKQESPDVHKRFQKVSEALTEDEQFLQSLTKDEMNKVITSQSNTSVEINSSQLLALPMPLQRRGVQLILNYLYENVPSSFSAHHIQQFLDWAENGGPSGVLDFPKGLKVVKSYQTCLFTFEQWQCKNVPFEYQISGAADETAVLPNGYLIEARHYADSPEEHGNAVFITSEKKVRFPLTIRTRKAGDRIKLKGMNGSKKVKDIFIDKKLPLQERDNWPIVTDASGEIIWIPGLKKSIFEDLVIPNSDRIVLQYRQHEKCRGQAKS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	472 (407)
Sequences:	2956 (2554)
Seq/√Len:	126.6

ECOLI - TILS TTCA
BACSU - TILS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
31_M	71_Y	3.922	1.00
60_E	188_E	3.833	1.00
53_D	62_E	3.789	1.00
193_D	203_T	3.602	1.00
32_A	177_C	3.201	1.00
193_D	202_K	2.928	1.00
82_A	111_E	2.777	1.00
170_K	174_L	2.721	1.00
49_A	72_C	2.684	1.00
209_K	216_H	2.629	1.00
48_I	80_E	2.596	1.00
128_D	216_H	2.587	1.00
65_M	69_Q	2.584	1.00
50_A	108_F	2.566	1.00
405_K	413_D	2.493	1.00
53_D	61_S	2.469	1.00
131_V	219_F	2.468	1.00
65_M	81_T	2.462	1.00
49_A	77_L	2.434	1.00
35_H	176_Y	2.406	1.00
28_P	177_C	2.400	1.00
53_D	65_M	2.390	1.00
34_L	49_A	2.361	1.00
24_V	68_V	2.356	1.00
55_R	83_Q	2.348	1.00
24_V	49_A	2.331	1.00
186_T	191_A	2.277	1.00
228_E	269_R	2.233	1.00
69_Q	73_K	2.207	1.00
235_S	264_P	2.203	1.00
20_I	122_A	2.195	1.00
113_M	121_L	2.191	1.00
134_M	223_S	2.157	1.00
268_Q	296_L	2.156	1.00
395_R	404_S	2.064	1.00
136_M	196_T	2.040	1.00
35_H	180_N	2.027	1.00
23_G	109_F	2.017	1.00
72_C	79_C	1.997	1.00
19_T	46_N	1.950	1.00
24_V	31_M	1.943	1.00
222_V	226_L	1.878	1.00
64_D	185_R	1.877	1.00
22_V	37_L	1.865	1.00
122_A	162_I	1.848	1.00
28_P	173_I	1.840	1.00
56_F	97_K	1.838	1.00
71_Y	75_E	1.836	1.00
48_I	118_A	1.833	1.00
28_P	32_A	1.825	1.00
35_H	75_E	1.802	1.00
411_F	424_W	1.781	1.00
22_V	33_L	1.759	1.00
134_M	219_F	1.750	1.00
444_I	447_D	1.744	1.00
63_E	185_R	1.739	1.00
18_A	120_Y	1.717	1.00
57_R	60_E	1.711	1.00
229_D	270_R	1.696	1.00
57_R	188_E	1.695	1.00
232_F	236_L	1.690	1.00
31_M	182_L	1.687	1.00
236_L	239_D	1.676	1.00
428_T	434_I	1.675	1.00
387_I	427_V	1.666	1.00
35_H	182_L	1.665	1.00
396_I	410_I	1.665	1.00
256_N	259_Q	1.663	1.00
130_Q	150_M	1.645	1.00
426_I	434_I	1.645	1.00
388_R	394_D	1.644	1.00
21_I	118_A	1.636	1.00
99_A	103_D	1.630	1.00
139_A	208_L	1.627	1.00
390_R	422_D	1.624	1.00
24_V	71_Y	1.623	1.00
138_L	222_V	1.612	1.00
66_R	69_Q	1.608	1.00
56_F	87_T	1.603	1.00
123_L	161_I	1.597	1.00
145_T	230_E	1.591	1.00
70_A	74_A	1.583	1.00
408_K	412_I	1.574	1.00
28_P	186_T	1.573	1.00
65_M	83_Q	1.554	1.00
38_H	77_L	1.536	1.00
19_T	48_I	1.530	1.00
254_E	322_T	1.522	1.00
36_A	165_F	1.522	1.00
238_K	274_L	1.512	1.00
21_I	48_I	1.504	1.00
52_V	84_I	1.504	1.00
98_Q	189_S	1.499	1.00
200_F	204_V	1.497	1.00
36_A	40_L	1.495	1.00
62_E	83_Q	1.484	1.00
258_S	321_Q	1.480	1.00
144_G	226_L	1.469	1.00
35_H	39_T	1.465	1.00
199_R	211_E	1.454	1.00
50_A	112_I	1.441	1.00
21_I	112_I	1.438	1.00
18_A	119_D	1.433	1.00
429_D	433_E	1.430	1.00
203_T	207_F	1.408	1.00
58_G	64_D	1.407	1.00
32_A	176_Y	1.398	1.00
435_I	446_E	1.392	1.00
38_H	75_E	1.392	1.00
351_L	354_G	1.386	1.00
240_E	267_L	1.383	1.00
131_V	205_L	1.377	1.00
175_H	179_E	1.371	1.00
407_V	411_F	1.364	1.00
52_V	82_A	1.363	1.00
34_L	72_C	1.362	1.00
410_I	437_I	1.360	1.00
37_L	122_A	1.352	1.00
72_C	77_L	1.345	1.00
433_E	445_F	1.342	1.00
428_T	432_G	1.335	1.00
225_A	289_A	1.330	1.00
390_R	393_G	1.324	1.00
86_V	104_C	1.320	1.00
169_T	172_E	1.310	1.00
50_A	109_F	1.308	1.00
23_G	123_L	1.308	1.00
127_G	220_Q	1.306	1.00
103_D	107_Q	1.298	1.00
31_M	67_F	1.289	1.00
151_Q	154_R	1.286	1.00
134_M	149_G	1.286	1.00
131_V	223_S	1.263	1.00
66_R	70_A	1.256	1.00
69_Q	79_C	1.256	1.00
174_L	178_H	1.255	1.00
388_R	428_T	1.231	1.00
110_E	113_M	1.231	1.00
204_V	208_L	1.228	0.99
241_M	245_I	1.222	0.99
80_E	115_K	1.221	0.99
153_V	160_R	1.219	0.99
237_T	271_G	1.217	0.99
257_S	318_K	1.216	0.99
98_Q	192_K	1.208	0.99
96_N	99_A	1.206	0.99
98_Q	195_Y	1.205	0.99
49_A	79_C	1.202	0.99
106_Y	123_L	1.199	0.99
177_C	184_Y	1.198	0.99
230_E	234_Q	1.194	0.99
171_E	209_K	1.186	0.99
95_L	103_D	1.180	0.99
147_L	222_V	1.176	0.99
316_V	325_F	1.166	0.99
177_C	182_L	1.164	0.99
53_D	83_Q	1.161	0.99
409_D	412_I	1.160	0.99
389_T	425_P	1.160	0.99
407_V	437_I	1.159	0.99
28_P	174_L	1.153	0.99
256_N	321_Q	1.150	0.99
128_D	209_K	1.148	0.99
426_I	437_I	1.143	0.99
84_I	104_C	1.138	0.99
86_V	100_A	1.138	0.99
424_W	440_L	1.134	0.99
131_V	216_H	1.128	0.99
131_V	220_Q	1.124	0.99
96_N	100_A	1.121	0.99
176_Y	180_N	1.118	0.99
214_D	218_R	1.115	0.99
272_V	295_F	1.111	0.99
126_H	173_I	1.110	0.99
139_A	219_F	1.110	0.99
143_L	146_G	1.104	0.99
208_L	215_V	1.102	0.99
97_K	195_Y	1.097	0.99
69_Q	81_T	1.095	0.99
225_A	229_D	1.093	0.99
291_H	311_P	1.088	0.99
67_F	185_R	1.086	0.99
215_V	219_F	1.078	0.99
390_R	408_K	1.076	0.99
295_F	316_V	1.070	0.99
142_T	146_G	1.069	0.99
134_M	138_L	1.062	0.99
165_F	168_I	1.060	0.98
409_D	413_D	1.058	0.98
320_Y	415_K	1.056	0.98
139_A	212_S	1.055	0.98
38_H	41_C	1.052	0.98
21_I	50_A	1.049	0.98
39_T	180_N	1.045	0.98
144_G	229_D	1.044	0.98
218_R	221_K	1.041	0.98
63_E	66_R	1.034	0.98
239_D	243_K	1.034	0.98
57_R	64_D	1.032	0.98
240_E	263_L	1.032	0.98
384_P	430_A	1.029	0.98
52_V	108_F	1.029	0.98
171_E	175_H	1.027	0.98
95_L	100_A	1.025	0.98
376_T	435_I	1.022	0.98
397_K	404_S	1.017	0.98
36_A	168_I	1.012	0.98
22_V	47_V	1.012	0.98
294_Q	298_W	1.012	0.98
410_I	440_L	1.004	0.98
51_H	65_M	0.997	0.98
231_Q	264_P	0.995	0.98
104_C	107_Q	0.995	0.98
113_M	159_G	0.993	0.98
55_R	62_E	0.993	0.98
425_P	438_P	0.992	0.98
399_K	447_D	0.989	0.98
203_T	210_Q	0.988	0.98
315_K	326_T	0.987	0.98
67_F	184_Y	0.986	0.98
154_R	159_G	0.986	0.98
31_M	184_Y	0.985	0.98
80_E	116_H	0.980	0.97
229_D	233_L	0.979	0.97
82_A	108_F	0.977	0.97
63_E	188_E	0.976	0.97
390_R	394_D	0.975	0.97
111_E	115_K	0.974	0.97
49_A	68_V	0.974	0.97
240_E	244_V	0.972	0.97
148_A	151_Q	0.971	0.97
152_P	167_T	0.970	0.97
127_G	216_H	0.967	0.97
233_L	270_R	0.963	0.97
110_E	160_R	0.963	0.97
28_P	170_K	0.961	0.97
429_D	435_I	0.961	0.97
68_V	79_C	0.955	0.97
31_M	75_E	0.955	0.97
390_R	426_I	0.950	0.97
263_L	271_G	0.947	0.97
204_V	207_F	0.941	0.97
189_S	192_K	0.941	0.97
309_D	315_K	0.939	0.97
174_L	186_T	0.936	0.97
381_V	429_D	0.932	0.97
40_L	45_A	0.929	0.97
135_L	200_F	0.927	0.96
377_S	381_V	0.924	0.96
34_L	47_V	0.920	0.96
169_T	216_H	0.919	0.96
107_Q	111_E	0.919	0.96
123_L	150_M	0.918	0.96
113_M	118_A	0.918	0.96
120_Y	162_I	0.912	0.96
134_M	142_T	0.909	0.96
443_S	446_E	0.908	0.96
256_N	322_T	0.906	0.96
237_T	274_L	0.902	0.96
70_A	73_K	0.902	0.96
189_S	198_N	0.902	0.96
28_P	184_Y	0.901	0.96
385_L	435_I	0.900	0.96
377_S	380_K	0.899	0.96
269_R	293_Q	0.898	0.96
60_E	63_E	0.896	0.96
199_R	202_K	0.896	0.96
19_T	119_D	0.895	0.96
417_P	420_E	0.893	0.96
214_D	217_K	0.891	0.96
386_T	428_T	0.890	0.96
442_K	447_D	0.885	0.95
31_M	68_V	0.883	0.95
150_M	154_R	0.882	0.95
137_K	142_T	0.881	0.95
414_K	441_K	0.879	0.95
317_V	326_T	0.872	0.95
216_H	220_Q	0.871	0.95
50_A	82_A	0.866	0.95
410_I	441_K	0.865	0.95
126_H	170_K	0.863	0.95
97_K	101_A	0.862	0.95
21_I	80_E	0.862	0.95
257_S	323_C	0.859	0.95
48_I	116_H	0.859	0.95
20_I	162_I	0.857	0.95
135_L	223_S	0.845	0.94
20_I	37_L	0.842	0.94
151_Q	227_T	0.841	0.94
142_T	222_V	0.840	0.94
80_E	112_I	0.839	0.94
390_R	407_V	0.838	0.94
348_T	351_L	0.834	0.94
82_A	112_I	0.832	0.94
192_K	202_K	0.832	0.94
98_Q	194_D	0.830	0.94
192_K	195_Y	0.828	0.93
41_C	45_A	0.819	0.93
53_D	188_E	0.815	0.93
110_E	159_G	0.809	0.93
349_A	352_P	0.808	0.93
394_D	428_T	0.805	0.93
318_K	321_Q	0.805	0.93
412_I	415_K	0.800	0.92
352_P	355_Y	0.798	0.92
37_L	47_V	0.798	0.92
220_Q	223_S	0.797	0.92
32_A	165_F	0.796	0.92
127_G	169_T	0.792	0.92
215_V	218_R	0.791	0.92
32_A	173_I	0.790	0.92
207_F	210_Q	0.789	0.92
387_I	425_P	0.788	0.92
234_Q	274_L	0.787	0.92
168_I	173_I	0.786	0.92
244_V	259_Q	0.785	0.92
150_M	166_L	0.784	0.92
397_K	444_I	0.784	0.92
209_K	215_V	0.780	0.91
134_M	147_L	0.780	0.91
23_G	61_S	0.777	0.91
238_K	242_N	0.775	0.91
233_L	237_T	0.773	0.91
265_M	268_Q	0.773	0.91
424_W	438_P	0.772	0.91
246_T	256_N	0.772	0.91
420_E	423_N	0.770	0.91
22_V	49_A	0.768	0.91
351_L	355_Y	0.767	0.91
385_L	429_D	0.767	0.91
233_L	236_L	0.764	0.90
136_M	200_F	0.763	0.90
237_T	270_R	0.761	0.90
376_T	442_K	0.758	0.90
58_G	185_R	0.758	0.90
241_M	274_L	0.756	0.90
288_S	291_H	0.755	0.90
294_Q	297_D	0.753	0.90
20_I	120_Y	0.752	0.90
205_L	219_F	0.751	0.90
207_F	211_E	0.751	0.90
26_G	68_V	0.750	0.90
348_T	352_P	0.750	0.90
383_F	429_D	0.749	0.90
230_E	233_L	0.748	0.89
84_I	108_F	0.748	0.89
236_L	240_E	0.747	0.89
297_D	301_N	0.746	0.89
221_K	225_A	0.745	0.89
410_I	414_K	0.743	0.89
32_A	182_L	0.741	0.89
135_L	205_L	0.739	0.89
389_T	426_I	0.736	0.89
396_I	443_S	0.736	0.89
58_G	61_S	0.735	0.89
24_V	67_F	0.735	0.89
148_A	227_T	0.735	0.89
276_L	281_E	0.735	0.89
319_S	419_Q	0.733	0.89
303_G	306_G	0.733	0.89
320_Y	421_R	0.733	0.89
306_G	311_P	0.732	0.88
274_L	277_N	0.732	0.88
436_W	439_G	0.732	0.88
35_H	38_H	0.729	0.88
67_F	71_Y	0.728	0.88
403_G	413_D	0.727	0.88
411_F	426_I	0.727	0.88
196_T	199_R	0.726	0.88
139_A	204_V	0.726	0.88
48_I	78_V	0.725	0.88
170_K	173_I	0.724	0.88
189_S	194_D	0.724	0.88
106_Y	154_R	0.722	0.88
296_L	300_E	0.722	0.88
32_A	35_H	0.720	0.88
95_L	99_A	0.719	0.88
406_K	409_D	0.718	0.88
126_H	165_F	0.718	0.88
130_Q	166_L	0.716	0.87
411_F	425_P	0.714	0.87
442_K	446_E	0.712	0.87
196_T	211_E	0.710	0.87
55_R	86_V	0.709	0.87
27_G	30_S	0.708	0.87
291_H	294_Q	0.708	0.87
411_F	437_I	0.706	0.87
134_M	226_L	0.705	0.87
113_M	160_R	0.705	0.87
237_T	240_E	0.703	0.86
255_I	275_I	0.701	0.86
355_Y	360_R	0.701	0.86
260_L	268_Q	0.700	0.86
398_L	401_M	0.698	0.86
128_D	171_E	0.697	0.86
270_R	274_L	0.696	0.86
51_H	64_D	0.696	0.86
33_L	37_L	0.695	0.86
25_S	30_S	0.694	0.86
25_S	29_D	0.694	0.86
253_V	275_I	0.694	0.86
229_D	266_P	0.689	0.85
134_M	222_V	0.688	0.85
109_F	113_M	0.687	0.85
112_I	116_H	0.685	0.85
383_F	430_A	0.681	0.85
121_L	159_G	0.681	0.85
67_F	183_S	0.680	0.85
414_K	440_L	0.676	0.84
433_E	446_E	0.676	0.84
416_L	421_R	0.675	0.84
60_E	64_D	0.674	0.84
239_D	242_N	0.674	0.84
199_R	207_F	0.674	0.84
356_L	360_R	0.673	0.84
176_Y	182_L	0.671	0.84
128_D	170_K	0.671	0.84
87_T	189_S	0.671	0.84
110_E	121_L	0.669	0.84
416_L	424_W	0.669	0.84
315_K	328_E	0.668	0.83
139_A	211_E	0.667	0.83
264_P	267_L	0.667	0.83
67_F	182_L	0.665	0.83
80_E	118_A	0.664	0.83
293_Q	297_D	0.663	0.83
48_I	119_D	0.663	0.83
298_W	308_L	0.663	0.83
243_K	259_Q	0.662	0.83
130_Q	137_K	0.660	0.83
121_L	161_I	0.659	0.83
109_F	123_L	0.659	0.83
347_E	350_V	0.657	0.82
240_E	270_R	0.657	0.82
343_G	346_D	0.656	0.82
131_V	215_V	0.654	0.82
137_K	222_V	0.654	0.82
406_K	412_I	0.652	0.82
276_L	287_F	0.649	0.82
37_L	45_A	0.649	0.82
261_L	300_E	0.647	0.82
22_V	34_L	0.645	0.81
175_H	178_H	0.645	0.81
139_A	200_F	0.642	0.81
57_R	61_S	0.638	0.81
109_F	121_L	0.638	0.81
267_L	270_R	0.636	0.80
274_L	278_Y	0.635	0.80
139_A	215_V	0.635	0.80
86_V	96_N	0.635	0.80
436_W	442_K	0.635	0.80
34_L	71_Y	0.634	0.80
23_G	106_Y	0.633	0.80
193_D	199_R	0.630	0.80
320_Y	412_I	0.630	0.80
61_S	65_M	0.628	0.80
224_E	289_A	0.627	0.79
56_F	98_Q	0.627	0.79
228_E	265_M	0.626	0.79
71_Y	182_L	0.626	0.79
64_D	68_V	0.623	0.79
177_C	186_T	0.621	0.79
275_I	299_A	0.620	0.79
305_S	308_L	0.618	0.78
35_H	177_C	0.615	0.78
58_G	188_E	0.615	0.78
416_L	440_L	0.615	0.78
395_R	409_D	0.614	0.78
427_V	438_P	0.609	0.77
64_D	189_S	0.609	0.77
263_L	267_L	0.607	0.77
148_A	226_L	0.606	0.77
32_A	180_N	0.604	0.77
382_R	429_D	0.603	0.77
266_P	270_R	0.603	0.77
61_S	101_A	0.603	0.77
165_F	173_I	0.601	0.77
130_Q	149_G	0.601	0.77
31_M	183_S	0.601	0.77
100_A	104_C	0.600	0.76
65_M	79_C	0.600	0.76
106_Y	161_I	0.600	0.76
399_K	403_G	0.599	0.76
145_T	234_Q	0.598	0.76
180_N	183_S	0.597	0.76
199_R	210_Q	0.597	0.76
31_M	177_C	0.596	0.76
368_E	375_I	0.595	0.76
289_A	293_Q	0.593	0.76
391_K	394_D	0.593	0.76
143_L	273_Q	0.590	0.75
268_Q	300_E	0.590	0.75
101_A	109_F	0.589	0.75
204_V	211_E	0.586	0.75
189_S	195_Y	0.584	0.74
429_D	446_E	0.584	0.74
348_T	358_E	0.579	0.74
307_V	310_F	0.578	0.74
39_T	176_Y	0.578	0.74
51_H	79_C	0.578	0.74
178_H	184_Y	0.578	0.74
273_Q	408_K	0.571	0.73
385_L	430_A	0.570	0.73
84_I	101_A	0.569	0.73
378_E	381_V	0.567	0.72
433_E	443_S	0.566	0.72
35_H	71_Y	0.566	0.72
386_T	432_G	0.566	0.72
381_V	384_P	0.565	0.72
34_L	77_L	0.565	0.72
261_L	268_Q	0.563	0.72
148_A	230_E	0.563	0.72
68_V	185_R	0.562	0.72
390_R	412_I	0.562	0.72
26_G	30_S	0.561	0.72
26_G	29_D	0.561	0.72
52_V	104_C	0.561	0.72
403_G	406_K	0.560	0.71
339_Y	342_S	0.559	0.71
265_M	293_Q	0.559	0.71
199_R	204_V	0.559	0.71
396_I	407_V	0.553	0.70
236_L	267_L	0.552	0.70
237_T	241_M	0.552	0.70
307_V	315_K	0.549	0.70
244_V	263_L	0.548	0.70
430_A	433_E	0.546	0.70
349_A	354_G	0.546	0.70
147_L	226_L	0.545	0.69
319_S	324_L	0.543	0.69
131_V	134_M	0.543	0.69
131_V	135_L	0.540	0.69
24_V	79_C	0.540	0.69
199_R	208_L	0.539	0.69
390_R	411_F	0.538	0.68
127_G	217_K	0.538	0.68
195_Y	390_R	0.537	0.68
112_I	115_K	0.537	0.68
305_S	310_F	0.537	0.68
60_E	185_R	0.537	0.68
436_W	441_K	0.537	0.68
203_T	211_E	0.536	0.68
230_E	270_R	0.536	0.68
314_L	325_F	0.535	0.68
269_R	296_L	0.535	0.68
437_I	440_L	0.535	0.68
38_H	182_L	0.535	0.68
143_L	147_L	0.535	0.68
199_R	212_S	0.534	0.68
396_I	405_K	0.534	0.68
84_I	100_A	0.533	0.68
348_T	353_N	0.533	0.68
320_Y	413_D	0.533	0.68
396_I	440_L	0.533	0.68
138_L	226_L	0.532	0.68
275_I	279_L	0.532	0.68
37_L	41_C	0.532	0.68
337_F	343_G	0.530	0.67
22_V	122_A	0.530	0.67
67_F	177_C	0.530	0.67
55_R	84_I	0.529	0.67
143_L	225_A	0.528	0.67
425_P	428_T	0.527	0.67
272_V	292_I	0.526	0.67
379_K	429_D	0.526	0.67
399_K	444_I	0.525	0.67
308_L	311_P	0.524	0.66
71_Y	74_A	0.523	0.66
141_G	146_G	0.523	0.66
54_H	108_F	0.523	0.66
338_E	341_I	0.522	0.66
28_P	64_D	0.522	0.66
19_T	118_A	0.522	0.66
127_G	215_V	0.521	0.66
62_E	66_R	0.521	0.66
134_M	220_Q	0.521	0.66
205_L	215_V	0.521	0.66
20_I	45_A	0.521	0.66
61_S	185_R	0.519	0.66
428_T	435_I	0.519	0.66
376_T	379_K	0.519	0.66
290_H	294_Q	0.519	0.66
222_V	225_A	0.518	0.66
104_C	137_K	0.517	0.65
106_Y	163_R	0.517	0.65
305_S	311_P	0.516	0.65
32_A	126_H	0.515	0.65
56_F	62_E	0.514	0.65
135_L	139_A	0.512	0.65
276_L	325_F	0.510	0.64
407_V	410_I	0.510	0.64
96_N	403_G	0.510	0.64
237_T	267_L	0.510	0.64
212_S	218_R	0.509	0.64
314_L	327_F	0.509	0.64
291_H	298_W	0.509	0.64
305_S	418_L	0.508	0.64
191_A	194_D	0.508	0.64
31_M	35_H	0.507	0.64
52_V	109_F	0.506	0.64
275_I	325_F	0.503	0.63
19_T	117_Q	0.503	0.63
238_K	278_Y	0.502	0.63
384_P	429_D	0.502	0.63
113_M	119_D	0.501	0.63
36_A	39_T	0.501	0.63
313_G	328_E	0.501	0.63
54_H	84_I	0.501	0.63
339_Y	343_G	0.500	0.63
144_G	225_A	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3a2kA	1	0.9725	100	0.214	Contact Map
1ni5A	2	0.9068	100	0.309	Contact Map
1wy5A	4	0.6398	100	0.45	Contact Map
3vrhA	2	0.5403	100	0.647	Contact Map
3rjzA	2	0.4322	100	0.735	Contact Map
3uowA	2	0.572	100	0.743	Contact Map
2vxoA	2	0.7182	100	0.744	Contact Map
2dplA	2	0.5657	100	0.748	Contact Map
1zunA	1	0.3581	100	0.753	Contact Map
1surA	2	0.3792	100	0.755	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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