GREMLIN Database
YABQ - Spore protein YabQ
UniProt: P37559 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 211 (186)
Sequences: 210 (182)
Seq/√Len: 13.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
29_L96_K3.9671.00
84_Q88_K3.8440.99
26_T91_Y3.6370.99
27_Y45_D3.3760.99
50_I108_F2.4780.91
91_Y95_L2.3460.88
19_W61_L2.3020.87
1_M9_T2.2940.87
29_L88_K2.2690.87
3_L6_Q2.1420.83
60_L64_N2.1300.83
51_M55_L2.0890.82
130_W133_A1.9960.78
106_Y110_K1.9950.78
48_F95_L1.9250.76
1_M6_Q1.9070.75
26_T95_L1.8580.73
59_V77_L1.8390.72
49_W64_N1.7230.67
9_T13_M1.7200.67
24_L75_A1.7190.67
7_F48_F1.6810.65
58_Y95_L1.6630.64
125_C137_K1.6410.63
47_L54_L1.6300.63
121_I157_L1.6230.62
76_V142_L1.6080.62
42_F45_D1.6020.61
46_I145_F1.5850.60
78_L82_T1.5630.59
89_R94_I1.5320.58
6_Q9_T1.5220.57
2_T178_L1.5010.56
34_A45_D1.4890.56
78_L81_A1.4870.55
52_Q58_Y1.4720.55
121_I156_V1.4700.55
110_K113_I1.4690.54
57_F64_N1.4370.53
119_R122_V1.4200.52
29_L84_Q1.4120.51
31_V36_T1.4120.51
129_I155_M1.3780.50
7_F46_I1.3750.50
112_L161_I1.3690.49
56_F76_V1.3550.48
164_I178_L1.3550.48
98_V190_F1.3520.48
50_I112_L1.3340.47
26_T48_F1.3180.46
171_L188_A1.3140.46
187_G190_F1.3130.46
23_S28_R1.3120.46
99_I146_L1.3080.46
125_C129_I1.3050.46
29_L75_A1.2820.45
160_P163_F1.2630.44
15_G85_S1.2610.44
11_L15_G1.2410.42
3_L9_T1.2390.42
75_A80_V1.2330.42
29_L52_Q1.2320.42
81_A85_S1.2310.42
27_Y76_V1.2270.42
26_T30_F1.2200.41
28_R31_V1.2130.41
9_T33_R1.2070.41
133_A137_K1.2000.40
46_I87_C1.1960.40
29_L80_V1.1930.40
111_K115_H1.1790.39
141_S148_L1.1770.39
106_Y123_W1.1680.39
38_R44_H1.1500.38
43_I125_C1.1460.38
98_V159_F1.1340.37
48_F163_F1.1290.37
51_M87_C1.1260.37
46_I157_L1.1210.36
5_T100_Y1.1190.36
103_V146_L1.1120.36
49_W120_P1.1040.36
93_K165_A1.0900.35
106_Y115_H1.0780.34
57_F60_L1.0780.34
39_W55_L1.0760.34
5_T9_T1.0750.34
75_A81_A1.0720.34
111_K145_F1.0570.33
117_L183_Y1.0560.33
128_I132_A1.0500.33
124_T178_L1.0440.33
3_L22_A1.0410.33
111_K146_L1.0330.32
46_I143_I1.0310.32
52_Q95_L1.0310.32
112_L131_L1.0300.32
117_L133_A1.0220.32
108_F177_R1.0210.32
159_F163_F1.0160.31
56_F134_F1.0130.31
56_F185_E1.0110.31
96_K188_A1.0080.31
1_M5_T1.0060.31
55_L110_K0.9970.31
161_I175_K0.9960.31
49_W73_F0.9940.30
30_F42_F0.9920.30
34_A42_F0.9870.30
16_M54_L0.9740.30
130_W137_K0.9740.30
87_C170_K0.9720.29
147_L153_I0.9640.29
56_F104_S0.9630.29
12_A129_I0.9620.29
48_F84_Q0.9600.29
29_L99_I0.9550.29
18_L171_L0.9480.28
26_T81_A0.9430.28
132_A173_P0.9350.28
62_H169_L0.9330.28
61_L65_E0.9300.28
172_L190_F0.9130.27
63_V91_Y0.9120.27
71_Y74_L0.9070.27
48_F52_Q0.9040.27
55_L135_L0.9010.26
109_F116_V0.8940.26
24_L128_I0.8900.26
24_L38_R0.8870.26
8_Y121_I0.8830.26
3_L67_E0.8830.26
9_T60_L0.8820.26
70_I136_F0.8800.26
153_I186_K0.8760.25
185_E190_F0.8700.25
166_K170_K0.8630.25
1_M13_M0.8560.25
125_C134_F0.8550.25
27_Y47_L0.8510.24
100_Y104_S0.8470.24
6_Q60_L0.8450.24
20_L94_I0.8420.24
94_I190_F0.8330.24
18_L87_C0.8320.24
7_F52_Q0.8170.23
130_W134_F0.8150.23
2_T7_F0.8150.23
52_Q91_Y0.8140.23
113_I168_C0.8130.23
42_F52_Q0.8100.23
153_I156_V0.8090.23
54_L105_V0.8040.23
67_E80_V0.8030.23
26_T75_A0.8010.23
24_L31_V0.8010.23
75_A78_L0.8000.22
136_F187_G0.7960.22
38_R55_L0.7880.22
116_V150_L0.7880.22
26_T42_F0.7840.22
111_K179_T0.7830.22
107_Q124_T0.7820.22
49_W60_L0.7800.22
67_E96_K0.7790.22
73_F86_L0.7730.22
12_A91_Y0.7710.21
28_R34_A0.7680.21
39_W59_V0.7640.21
16_M42_F0.7630.21
47_L70_I0.7620.21
53_G61_L0.7610.21
68_F97_F0.7600.21
33_R42_F0.7580.21
102_V149_C0.7550.21
121_I186_K0.7520.21
93_K101_L0.7480.21
157_L177_R0.7400.20
15_G37_A0.7380.20
48_F91_Y0.7380.20
61_L80_V0.7350.20
56_F161_I0.7340.20
59_V67_E0.7320.20
81_A94_I0.7320.20
17_G66_G0.7270.20
87_C128_I0.7250.20
72_I106_Y0.7240.20
18_L61_L0.7130.19
55_L104_S0.7110.19
21_G79_G0.7070.19
6_Q64_N0.7050.19
21_G74_L0.7030.19
48_F152_K0.7030.19
63_V145_F0.6990.19
122_V172_L0.6900.19
98_V116_V0.6890.19
128_I142_L0.6840.19
114_Q145_F0.6790.18
114_Q119_R0.6770.18
24_L36_T0.6760.18
125_C147_L0.6760.18
3_L7_F0.6710.18
27_Y42_F0.6670.18
17_G79_G0.6640.18
2_T81_A0.6600.18
75_A84_Q0.6590.18
112_L187_G0.6500.17
90_I105_V0.6440.17
170_K185_E0.6420.17
59_V187_G0.6410.17
30_F95_L0.6390.17
49_W57_F0.6330.17
80_V88_K0.6300.17
31_V163_F0.6280.17
66_G79_G0.6250.17
75_A96_K0.6250.17
123_W188_A0.6250.17
87_C187_G0.6240.17
119_R123_W0.6230.17
12_A62_H0.6200.17
183_Y188_A0.6150.16
68_F149_C0.6110.16
138_K184_F0.6100.16
10_M82_T0.6080.16
9_T64_N0.6060.16
112_L127_A0.6030.16
2_T111_K0.6030.16
19_W45_D0.5970.16
179_T186_K0.5930.16
48_F58_Y0.5930.16
36_T44_H0.5910.16
156_V160_P0.5900.16
151_Y157_L0.5900.16
26_T63_V0.5900.16
43_I104_S0.5880.16
28_R45_D0.5870.16
33_R41_L0.5840.16
32_I139_T0.5820.15
20_L28_R0.5790.15
19_W130_W0.5780.15
100_Y158_C0.5770.15
78_L86_L0.5750.15
51_M167_Q0.5680.15
101_L128_I0.5670.15
46_I108_F0.5650.15
56_F88_K0.5640.15
117_L138_K0.5630.15
23_S92_I0.5600.15
40_L117_L0.5600.15
39_W57_F0.5590.15
4_T8_Y0.5580.15
42_F173_P0.5560.15
21_G83_Y0.5550.15
24_L80_V0.5520.15
106_Y124_T0.5520.15
178_L183_Y0.5500.15
27_Y44_H0.5500.15
179_T190_F0.5500.15
105_V116_V0.5490.15
100_Y153_I0.5460.14
59_V148_L0.5460.14
64_N120_P0.5400.14
52_Q80_V0.5390.14
26_T88_K0.5320.14
54_L124_T0.5310.14
160_P171_L0.5290.14
126_G135_L0.5280.14
81_A91_Y0.5270.14
16_M56_F0.5250.14
30_F167_Q0.5240.14
80_V84_Q0.5200.14
124_T161_I0.5160.14
144_G148_L0.5160.14
11_L171_L0.5100.14
132_A190_F0.5080.14
112_L128_I0.5070.14
85_S122_V0.5070.14
66_G120_P0.5060.13
41_L45_D0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pndA 3 0.1422 4.3 0.962 Contact Map
2lomA 1 0.1469 4 0.963 Contact Map
2k6oA 1 0.1754 2.5 0.967 Contact Map
1lypA 1 0.1517 2.3 0.967 Contact Map
2a9hA 4 0.4455 2.1 0.968 Contact Map
2fcgF 1 0.0853 1.8 0.969 Contact Map
1rh5B 1 0.1185 1.5 0.97 Contact Map
1orqC 4 0.4502 1.5 0.971 Contact Map
2ih3C 4 0.4455 1.4 0.971 Contact Map
4ogqB 1 0.3318 1.4 0.971 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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