GREMLIN Database
YABP - Spore protein YabP
UniProt: P37558 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 100 (90)
Sequences: 497 (368)
Seq/√Len: 38.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
47_T52_L4.4751.00
21_M27_L4.1571.00
52_L80_L3.8211.00
34_H60_Q2.8561.00
34_H70_I2.3601.00
32_V47_T2.3211.00
57_Q76_R2.2771.00
35_V45_L2.2681.00
40_N43_F1.8810.98
22_K26_H1.7790.97
36_E51_M1.7540.97
63_N72_S1.7300.97
60_Q66_V1.7000.96
77_V80_L1.5630.94
46_E51_M1.5460.94
21_M59_L1.4790.92
18_D22_K1.4760.92
84_D93_G1.4560.92
79_D92_K1.4540.92
29_I32_V1.4270.91
39_D98_L1.3960.90
39_D71_V1.3890.90
63_N70_I1.3780.89
16_Q97_K1.3720.89
58_N76_R1.2690.85
35_V60_Q1.2550.84
34_H65_D1.2550.84
41_E98_L1.2500.84
53_S81_V1.2210.83
15_E23_G1.2120.82
65_D68_K1.2100.82
69_G84_D1.2060.82
41_E99_F1.1550.79
43_F70_I1.1410.78
85_E96_S1.1300.78
61_M71_V1.1100.76
43_F62_K1.1100.76
47_T50_G1.0990.76
79_D91_A1.0580.73
17_H69_G1.0510.72
60_Q74_K1.0430.72
62_K94_F1.0380.71
39_D52_L1.0310.71
17_H72_S1.0210.70
61_M66_V1.0120.69
54_V86_Q1.0100.69
80_L85_E1.0070.69
41_E57_Q1.0030.69
37_S44_L0.9900.68
21_M95_F0.9680.66
55_R91_A0.9680.66
21_M80_L0.9630.65
30_S70_I0.9010.60
27_L35_V0.8960.60
23_G86_Q0.8850.59
42_E93_G0.8840.59
39_D84_D0.8780.58
39_D78_F0.8740.58
58_N86_Q0.8600.57
45_L62_K0.8250.54
55_R100_K0.8150.53
17_H49_M0.8090.52
26_H94_F0.8000.51
35_V66_V0.7990.51
45_L98_L0.7950.51
14_P52_L0.7920.51
51_M95_F0.7690.48
69_G97_K0.7660.48
40_N51_M0.7650.48
22_K97_K0.7600.48
15_E67_E0.7550.47
41_E64_L0.7530.47
15_E80_L0.7430.46
44_L51_M0.7370.46
74_K96_S0.7370.46
30_S99_F0.7360.46
67_E74_K0.7340.45
18_D43_F0.7340.45
16_Q30_S0.7190.44
14_P99_F0.7140.44
84_D92_K0.7100.43
26_H33_K0.7080.43
66_V86_Q0.7010.42
37_S100_K0.6970.42
96_S100_K0.6950.42
21_M26_H0.6940.42
29_I85_E0.6940.42
57_Q96_S0.6870.41
89_D93_G0.6860.41
15_E48_V0.6830.41
57_Q91_A0.6800.41
89_D92_K0.6780.40
45_L71_V0.6510.38
63_N99_F0.6480.38
41_E68_K0.6450.38
14_P19_V0.6400.37
40_N60_Q0.6320.36
63_N68_K0.6290.36
77_V93_G0.6260.36
14_P90_K0.6250.36
33_K58_N0.6200.35
36_E83_L0.6150.35
66_V74_K0.5990.34
19_V67_E0.5980.34
30_S82_Y0.5930.33
21_M52_L0.5850.33
35_V91_A0.5810.32
69_G98_L0.5780.32
39_D81_V0.5750.32
49_M77_V0.5670.31
34_H51_M0.5640.31
18_D23_G0.5640.31
16_Q99_F0.5610.31
27_L68_K0.5610.31
34_H76_R0.5550.30
13_V76_R0.5540.30
40_N58_N0.5540.30
79_D98_L0.5520.30
68_K71_V0.5440.29
54_V82_Y0.5430.29
45_L54_V0.5400.29
73_I76_R0.5380.29
29_I40_N0.5340.29
19_V96_S0.5250.28
42_E53_S0.5220.28
23_G91_A0.5220.28
62_K74_K0.5220.28
14_P21_M0.5220.28
20_T28_D0.5190.28
15_E100_K0.5180.28
41_E44_L0.5150.27
49_M98_L0.5100.27
90_K98_L0.5010.26
16_Q86_Q0.5010.26
43_F65_D0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ks0A 2 0.66 99.7 0.453 Contact Map
3f2bA 1 0.43 27.1 0.906 Contact Map
2og2A 1 0 4.7 0.934 Contact Map
1ycyA 5 0.62 3.7 0.937 Contact Map
1yoxA 3 0.42 3.1 0.94 Contact Map
2yh5A 1 0.59 2.9 0.94 Contact Map
2bolA 2 0.76 2.6 0.942 Contact Map
2x55A 1 0.61 2.2 0.944 Contact Map
4fmrA 2 0.93 1.9 0.946 Contact Map
1xaxA 1 0.93 1.9 0.946 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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