PURR - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PURR - Pur operon repressor

UniProt:	P37551	Sequences: MKFRRSGRLVDLTNYLLTHPHELIPLTFFSERYESAKSSISEDLTIIKQTFEQQGIGTLLTVPGAAGGVKYIPKMKQAEAEEFVQTLGQSLANPERILPGGYVYLTDILGKPSVLSKVGKLFASVFAEREIDVVMTVATKGIPLAYAAASYLNVPVVIVRKDNKVTEGSTVSINYVSGSSNRIQTMSLAKRSMKTGSNVLIIDDFMKAGGTINGMINLLDEFNANVAGIGVLVEAEGVDERLVDEYMSLLTLSTINMKEKSIEIQNGNFLRFFKDNLLKNGETES	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	285 (267)
Sequences:	436 (252)
Seq/√Len:	15.4

BACSU - PURR
SULSO - Q980Q2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
198_N	225_N	6.063	1.00
195_T	223_N	5.400	1.00
126_F	230_G	3.778	1.00
135_M	159_V	3.299	0.99
60_L	70_K	3.153	0.99
122_F	230_G	2.981	0.98
202_I	230_G	2.931	0.98
83_F	114_V	2.909	0.98
14_N	18_T	2.782	0.97
23_L	62_V	2.650	0.96
14_N	56_I	2.612	0.95
135_M	215_M	2.605	0.95
122_F	126_F	2.593	0.95
19_H	22_E	2.497	0.94
131_I	154_V	2.466	0.94
11_D	33_Y	2.405	0.93
84_V	249_L	2.279	0.91
146_Y	156_V	2.239	0.90
197_S	224_A	2.221	0.90
241_R	244_D	2.137	0.88
9_L	30_S	2.098	0.87
138_A	192_S	2.094	0.86
233_V	252_L	2.079	0.86
200_L	228_G	2.021	0.84
201_I	215_M	2.010	0.84
165_V	233_V	1.973	0.83
181_N	208_A	1.911	0.81
5_R	8_R	1.852	0.79
116_S	150_S	1.763	0.75
115_L	146_Y	1.717	0.73
164_K	213_N	1.708	0.73
55_G	196_G	1.700	0.72
173_I	252_L	1.688	0.72
187_S	217_N	1.670	0.71
66_A	72_I	1.652	0.70
173_I	184_Q	1.646	0.70
66_A	157_V	1.641	0.70
181_N	185_T	1.638	0.69
137_V	161_K	1.632	0.69
148_A	170_T	1.619	0.68
110_G	158_I	1.605	0.68
39_S	267_G	1.596	0.67
105_L	161_K	1.571	0.66
158_I	192_S	1.554	0.65
207_K	229_I	1.536	0.64
132_D	197_S	1.536	0.64
135_M	219_L	1.527	0.64
90_S	93_N	1.516	0.63
35_S	40_I	1.510	0.63
134_V	152_L	1.505	0.63
40_I	44_L	1.499	0.62
164_K	250_L	1.489	0.62
86_T	130_E	1.486	0.62
106_T	157_V	1.469	0.61
86_T	134_V	1.459	0.60
105_L	187_S	1.447	0.59
16_L	19_H	1.445	0.59
5_R	193_M	1.440	0.59
175_Y	186_M	1.425	0.58
213_N	217_N	1.416	0.58
105_L	184_Q	1.411	0.57
206_M	243_V	1.402	0.57
234_E	238_V	1.377	0.56
219_L	226_V	1.373	0.55
196_G	224_A	1.371	0.55
115_L	232_L	1.365	0.55
75_M	197_S	1.359	0.55
166_T	207_K	1.359	0.55
86_T	117_K	1.355	0.54
130_E	198_N	1.344	0.54
46_I	192_S	1.336	0.53
142_I	224_A	1.326	0.53
10_V	13_T	1.321	0.52
126_F	202_I	1.314	0.52
133_V	193_M	1.313	0.52
24_I	218_L	1.304	0.51
157_V	164_K	1.304	0.51
44_L	59_L	1.298	0.51
154_V	207_K	1.280	0.50
174_N	210_G	1.265	0.49
137_V	162_D	1.262	0.49
235_A	238_V	1.261	0.49
144_L	184_Q	1.245	0.48
138_A	217_N	1.238	0.48
149_A	163_N	1.237	0.48
35_S	264_I	1.226	0.47
7_G	18_T	1.212	0.46
11_D	63_P	1.211	0.46
52_E	233_V	1.204	0.46
238_V	241_R	1.199	0.45
179_S	207_K	1.191	0.45
118_V	231_V	1.188	0.45
56_I	138_A	1.181	0.44
77_Q	81_E	1.180	0.44
88_G	264_I	1.174	0.44
159_V	182_R	1.166	0.44
88_G	250_L	1.162	0.43
86_T	111_K	1.144	0.42
198_N	227_A	1.142	0.42
139_T	167_E	1.142	0.42
174_N	188_L	1.138	0.42
91_L	161_K	1.135	0.42
25_P	110_G	1.134	0.42
94_P	224_A	1.131	0.42
122_F	202_I	1.125	0.41
9_L	59_L	1.114	0.41
71_Y	227_A	1.111	0.41
39_S	110_G	1.105	0.40
98_L	155_P	1.098	0.40
14_N	138_A	1.096	0.40
173_I	232_L	1.094	0.40
46_I	152_L	1.089	0.39
86_T	256_N	1.084	0.39
165_V	226_V	1.084	0.39
137_V	234_E	1.072	0.38
3_F	106_T	1.070	0.38
123_A	152_L	1.070	0.38
34_E	76_K	1.068	0.38
16_L	62_V	1.066	0.38
126_F	137_V	1.062	0.38
35_S	63_P	1.058	0.38
156_V	185_T	1.055	0.37
199_V	224_A	1.052	0.37
144_L	213_N	1.048	0.37
49_Q	53_Q	1.045	0.37
33_Y	118_V	1.039	0.37
2_K	106_T	1.027	0.36
137_V	177_S	1.015	0.35
4_R	34_E	1.015	0.35
21_H	25_P	1.014	0.35
4_R	183_I	1.011	0.35
46_I	171_V	1.010	0.35
198_N	245_E	1.004	0.35
71_Y	95_E	1.001	0.35
163_N	187_S	0.998	0.34
94_P	253_S	0.993	0.34
206_M	242_L	0.983	0.34
91_L	137_V	0.979	0.34
36_A	61_T	0.979	0.34
51_F	138_A	0.977	0.33
179_S	242_L	0.975	0.33
159_V	219_L	0.975	0.33
227_A	258_K	0.971	0.33
164_K	187_S	0.968	0.33
240_E	243_V	0.968	0.33
121_L	197_S	0.964	0.33
137_V	219_L	0.960	0.33
91_L	105_L	0.960	0.33
87_L	191_R	0.956	0.32
109_L	211_T	0.956	0.32
232_L	250_L	0.955	0.32
55_G	59_L	0.954	0.32
9_L	193_M	0.951	0.32
73_P	169_S	0.943	0.32
241_R	268_N	0.935	0.31
219_L	224_A	0.931	0.31
90_S	264_I	0.928	0.31
183_I	186_M	0.927	0.31
162_D	190_K	0.925	0.31
183_I	187_S	0.922	0.31
87_L	118_V	0.919	0.31
152_L	222_F	0.917	0.30
61_T	228_G	0.914	0.30
129_R	134_V	0.913	0.30
103_V	122_F	0.913	0.30
105_L	183_I	0.910	0.30
60_L	133_V	0.907	0.30
109_L	200_L	0.907	0.30
89_Q	92_A	0.901	0.30
176_V	255_I	0.899	0.30
108_I	259_E	0.897	0.29
50_T	249_L	0.894	0.29
76_K	108_I	0.893	0.29
21_H	169_S	0.889	0.29
148_A	195_T	0.888	0.29
115_L	156_V	0.887	0.29
33_Y	120_K	0.882	0.29
51_F	144_L	0.870	0.28
50_T	54_Q	0.869	0.28
52_E	116_S	0.868	0.28
111_K	114_V	0.867	0.28
84_V	144_L	0.865	0.28
72_I	202_I	0.863	0.28
7_G	146_Y	0.861	0.28
2_K	163_N	0.858	0.28
111_K	144_L	0.855	0.28
199_V	215_M	0.850	0.27
7_G	49_Q	0.846	0.27
170_T	190_K	0.840	0.27
150_S	241_R	0.839	0.27
138_A	154_V	0.839	0.27
90_S	111_K	0.836	0.27
103_V	173_I	0.835	0.27
4_R	80_A	0.832	0.26
4_R	7_G	0.825	0.26
18_T	95_E	0.818	0.26
49_Q	52_E	0.816	0.26
122_F	148_A	0.816	0.26
16_L	36_A	0.815	0.26
13_T	17_L	0.815	0.26
187_S	230_G	0.813	0.26
82_E	128_E	0.810	0.26
176_V	188_L	0.808	0.25
110_G	206_M	0.807	0.25
5_R	10_V	0.806	0.25
3_F	116_S	0.804	0.25
15_Y	24_I	0.799	0.25
252_L	255_I	0.796	0.25
253_S	265_Q	0.792	0.25
23_L	199_V	0.789	0.25
104_Y	198_N	0.788	0.25
15_Y	135_M	0.788	0.25
121_L	259_E	0.786	0.25
165_V	191_R	0.785	0.24
172_S	179_S	0.785	0.24
38_S	42_E	0.785	0.24
109_L	161_K	0.784	0.24
137_V	183_I	0.779	0.24
51_F	102_Y	0.775	0.24
16_L	28_F	0.773	0.24
39_S	151_Y	0.772	0.24
244_D	260_K	0.767	0.24
4_R	71_Y	0.766	0.24
118_V	153_N	0.766	0.24
229_I	268_N	0.765	0.24
55_G	76_K	0.759	0.23
264_I	268_N	0.759	0.23
138_A	148_A	0.758	0.23
206_M	235_A	0.754	0.23
21_H	135_M	0.751	0.23
105_L	181_N	0.749	0.23
71_Y	239_D	0.743	0.23
91_L	227_A	0.743	0.23
69_V	164_K	0.742	0.23
74_K	127_A	0.741	0.23
206_M	244_D	0.741	0.23
3_F	52_E	0.738	0.23
112_P	123_A	0.735	0.22
253_S	266_N	0.735	0.22
5_R	41_S	0.733	0.22
19_H	266_N	0.732	0.22
12_L	40_I	0.730	0.22
199_V	219_L	0.727	0.22
131_I	151_Y	0.726	0.22
116_S	233_V	0.724	0.22
135_M	228_G	0.724	0.22
172_S	208_A	0.715	0.22
52_E	252_L	0.707	0.21
18_T	83_F	0.703	0.21
60_L	202_I	0.698	0.21
213_N	241_R	0.697	0.21
28_F	108_I	0.692	0.21
71_Y	165_V	0.692	0.21
156_V	187_S	0.688	0.21
49_Q	184_Q	0.687	0.21
146_Y	185_T	0.682	0.20
66_A	87_L	0.680	0.20
75_M	121_L	0.676	0.20
2_K	8_R	0.675	0.20
32_R	44_L	0.675	0.20
47_I	54_Q	0.675	0.20
38_S	61_T	0.673	0.20
102_Y	233_V	0.670	0.20
2_K	44_L	0.670	0.20
91_L	128_E	0.669	0.20
110_G	267_G	0.668	0.20
19_H	97_I	0.668	0.20
156_V	184_Q	0.665	0.20
218_L	232_L	0.664	0.20
123_A	222_F	0.663	0.20
39_S	46_I	0.663	0.20
18_T	149_A	0.661	0.20
208_A	230_G	0.659	0.20
208_A	226_V	0.658	0.20
134_V	216_I	0.658	0.20
15_Y	202_I	0.655	0.19
33_Y	151_Y	0.655	0.19
161_K	184_Q	0.654	0.19
91_L	212_I	0.654	0.19
131_I	161_K	0.652	0.19
125_V	133_V	0.652	0.19
178_G	208_A	0.650	0.19
254_T	261_S	0.648	0.19
138_A	162_D	0.647	0.19
9_L	133_V	0.646	0.19
146_Y	219_L	0.646	0.19
255_I	260_K	0.644	0.19
184_Q	187_S	0.642	0.19
220_D	255_I	0.641	0.19
78_A	121_L	0.641	0.19
31_E	82_E	0.640	0.19
108_I	185_T	0.637	0.19
13_T	47_I	0.636	0.19
12_L	234_E	0.635	0.19
134_V	202_I	0.635	0.19
21_H	260_K	0.635	0.19
14_N	241_R	0.634	0.19
52_E	265_Q	0.631	0.19
76_K	79_E	0.630	0.19
114_V	232_L	0.626	0.18
33_Y	219_L	0.625	0.18
7_G	153_N	0.625	0.18
35_S	102_Y	0.624	0.18
69_V	161_K	0.623	0.18
71_Y	247_M	0.623	0.18
69_V	169_S	0.620	0.18
39_S	201_I	0.620	0.18
33_Y	40_I	0.616	0.18
86_T	227_A	0.614	0.18
62_V	131_I	0.613	0.18
72_I	78_A	0.613	0.18
126_F	247_M	0.611	0.18
174_N	189_A	0.610	0.18
7_G	189_A	0.610	0.18
50_T	238_V	0.609	0.18
103_V	177_S	0.609	0.18
30_S	123_A	0.606	0.18
7_G	30_S	0.606	0.18
59_L	207_K	0.604	0.18
237_G	244_D	0.603	0.18
144_L	232_L	0.602	0.18
44_L	127_A	0.597	0.17
155_P	199_V	0.593	0.17
195_T	202_I	0.592	0.17
82_E	86_T	0.592	0.17
39_S	106_T	0.592	0.17
208_A	237_G	0.591	0.17
148_A	262_I	0.590	0.17
36_A	42_E	0.589	0.17
153_N	185_T	0.589	0.17
130_E	245_E	0.588	0.17
87_L	211_T	0.587	0.17
81_E	197_S	0.587	0.17
3_F	266_N	0.585	0.17
111_K	238_V	0.584	0.17
78_A	82_E	0.582	0.17
41_S	222_F	0.580	0.17
10_V	73_P	0.577	0.17
140_K	160_R	0.573	0.17
50_T	250_L	0.573	0.17
164_K	190_K	0.572	0.17
4_R	118_V	0.572	0.17
29_F	214_G	0.570	0.17
14_N	108_I	0.570	0.17
195_T	224_A	0.568	0.16
33_Y	201_I	0.567	0.16
3_F	181_N	0.565	0.16
97_I	121_L	0.563	0.16
29_F	210_G	0.560	0.16
7_G	33_Y	0.557	0.16
88_G	225_N	0.556	0.16
121_L	172_S	0.552	0.16
48_K	61_T	0.552	0.16
82_E	191_R	0.551	0.16
118_V	248_S	0.551	0.16
4_R	49_Q	0.551	0.16
128_E	158_I	0.551	0.16
190_K	256_N	0.550	0.16
108_I	239_D	0.547	0.16
118_V	195_T	0.547	0.16
6_S	110_G	0.545	0.16
109_L	119_G	0.545	0.16
211_T	215_M	0.543	0.16
118_V	147_A	0.541	0.16
4_R	199_V	0.541	0.16
40_I	207_K	0.540	0.16
144_L	148_A	0.538	0.16
118_V	144_L	0.537	0.16
49_Q	198_N	0.537	0.16
224_A	251_T	0.535	0.15
4_R	169_S	0.535	0.15
106_T	173_I	0.534	0.15
190_K	213_N	0.534	0.15
184_Q	252_L	0.532	0.15
239_D	255_I	0.531	0.15
23_L	66_A	0.531	0.15
9_L	32_R	0.530	0.15
40_I	99_P	0.528	0.15
98_L	222_F	0.527	0.15
94_P	254_T	0.525	0.15
197_S	225_N	0.525	0.15
103_V	184_Q	0.524	0.15
30_S	135_M	0.524	0.15
101_G	119_G	0.523	0.15
106_T	201_I	0.522	0.15
48_K	69_V	0.522	0.15
10_V	212_I	0.518	0.15
75_M	249_L	0.517	0.15
74_K	85_Q	0.515	0.15
47_I	117_K	0.513	0.15
118_V	199_V	0.512	0.15
72_I	200_L	0.511	0.15
102_Y	138_A	0.510	0.15
234_E	248_S	0.507	0.15
207_K	211_T	0.506	0.15
70_K	247_M	0.506	0.15
134_V	154_V	0.505	0.15
3_F	24_I	0.505	0.15
48_K	199_V	0.502	0.15
31_E	129_R	0.500	0.14

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1o57A	2	0.9509	100	0.484	Contact Map
4lzaA	2	0.586	99.9	0.808	Contact Map
1y0bA	2	0.6526	99.9	0.809	Contact Map
4pawA	2	0.5684	99.9	0.814	Contact Map
1qb7A	2	0.7579	99.9	0.814	Contact Map
4m0kA	2	0.5965	99.9	0.815	Contact Map
3qw4B	4	0.8316	99.9	0.825	Contact Map
2wnsA	2	0.6421	99.9	0.827	Contact Map
2dy0A	2	0.614	99.8	0.831	Contact Map
3mjdA	2	0.6351	99.8	0.832	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0082 seconds.