GREMLIN Database
YAAT - Stage 0 sporulation protein YaaT
UniProt: P37541 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 275 (262)
Sequences: 1322 (776)
Seq/√Len: 48.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
96_H132_D5.3851.00
163_R169_T4.0901.00
228_T231_G4.0071.00
41_Y72_L3.9341.00
29_S66_V3.8701.00
81_E111_R3.8691.00
91_K95_E3.2511.00
32_I109_F3.1021.00
93_V102_L3.0891.00
171_L207_Y2.7951.00
3_N48_N2.7691.00
227_T232_P2.6681.00
218_Q243_R2.6631.00
103_V146_I2.6371.00
215_A243_R2.5781.00
26_E29_S2.4741.00
75_V79_K2.4191.00
25_I66_V2.3771.00
105_V114_V2.2961.00
89_C102_L2.2861.00
86_F93_V2.2651.00
184_D209_N2.2271.00
73_L76_E2.2091.00
69_D73_L2.2061.00
157_G165_L2.1301.00
76_E80_Q2.0651.00
23_F66_V2.0421.00
19_D62_K2.0160.99
30_C43_Q2.0150.99
230_N258_Y1.9850.99
39_V64_I1.9820.99
6_G15_I1.9020.99
32_I41_Y1.8970.99
92_K132_D1.8770.99
226_I233_A1.8280.99
65_R71_D1.7200.98
77_E81_E1.7120.98
88_I136_I1.7040.98
102_L116_F1.6690.98
88_I137_F1.6480.98
30_C72_L1.6360.98
118_F143_L1.6290.98
77_E80_Q1.6200.98
120_A124_V1.6040.97
88_I92_K1.5710.97
95_E136_I1.5700.97
87_D91_K1.5420.97
7_V31_V1.5210.96
219_L238_L1.5190.96
233_A249_L1.5120.96
30_C41_Y1.4900.96
80_Q84_S1.4530.95
211_E214_T1.4400.95
221_D224_E1.4330.95
89_C93_V1.4320.95
25_I44_V1.4310.95
232_P250_I1.4310.95
3_N50_Q1.4240.95
134_A141_I1.4210.95
118_F130_V1.3920.94
72_L76_E1.3880.94
231_G249_L1.3750.94
226_I263_L1.3610.93
106_E191_P1.3600.93
225_M232_P1.3560.93
148_V200_R1.3550.93
33_V61_R1.3420.93
148_V176_P1.3260.92
219_L243_R1.3180.92
18_F61_R1.3170.92
74_I77_E1.3170.92
233_A247_V1.3150.92
92_K96_H1.3060.92
23_F63_V1.3040.92
21_N62_K1.3000.92
226_I247_V1.2950.92
53_E56_V1.2930.91
164_M169_T1.2910.91
244_V259_T1.2840.91
3_N22_G1.2570.90
85_A116_F1.2510.90
209_N213_E1.2490.90
87_D90_Q1.2490.90
259_T262_E1.2480.90
165_L197_L1.2440.90
187_L190_N1.2330.89
41_Y109_F1.2100.88
37_R106_E1.2010.88
95_E132_D1.1970.88
116_F148_V1.1750.87
34_E61_R1.1610.86
76_E79_K1.1580.86
93_V129_L1.1540.86
82_A184_D1.1470.86
175_E206_K1.1450.86
195_S200_R1.1440.86
238_L241_L1.1370.85
3_N24_H1.1350.85
17_Y143_L1.1320.85
103_V119_T1.1320.85
5_I48_N1.1180.84
191_P194_I1.1130.84
99_D120_A1.1120.84
96_H128_E1.1060.84
9_F16_Y1.0930.83
82_A105_V1.0910.83
99_D122_G1.0870.82
160_P197_L1.0850.82
126_F145_Q1.0720.82
70_R74_I1.0710.81
25_I31_V1.0700.81
185_Q212_Y1.0690.81
157_G183_K1.0660.81
31_V63_V1.0620.81
234_K248_E1.0580.81
6_G46_I1.0570.81
121_D124_V1.0490.80
165_L169_T1.0430.80
120_A132_D1.0430.80
42_G61_R1.0310.79
16_Y33_V1.0280.79
130_V150_D1.0250.79
84_S87_D1.0130.78
215_A219_L1.0120.78
18_F35_T1.0080.77
28_D43_Q1.0010.77
209_N216_K0.9820.75
14_K121_D0.9810.75
228_T249_L0.9800.75
32_I71_D0.9780.75
118_F183_K0.9750.75
237_G242_E0.9720.75
228_T233_A0.9690.75
81_E107_F0.9630.74
151_E176_P0.9620.74
79_K82_A0.9620.74
239_N242_E0.9600.74
113_K119_T0.9560.74
41_Y75_V0.9550.73
157_G188_S0.9520.73
35_T38_G0.9500.73
134_A137_F0.9430.72
118_F181_M0.9420.72
89_C133_L0.9410.72
192_T200_R0.9410.72
78_N111_R0.9300.71
98_L132_D0.9280.71
158_I187_L0.9210.71
197_L243_R0.9180.70
118_F139_T0.9140.70
114_V139_T0.9130.70
16_Y35_T0.9110.70
100_M126_F0.8990.69
118_F150_D0.8980.69
105_V143_L0.8890.68
62_K124_V0.8890.68
219_L260_W0.8880.68
16_Y61_R0.8840.68
216_K238_L0.8810.67
27_H47_A0.8760.67
99_D180_K0.8720.66
9_F14_K0.8680.66
27_H43_Q0.8640.66
85_A118_F0.8630.66
245_L263_L0.8620.66
111_R114_V0.8580.65
234_K243_R0.8540.65
239_N244_V0.8490.64
237_G246_Q0.8490.64
194_I202_M0.8490.64
164_M168_S0.8490.64
37_R42_G0.8440.64
5_I63_V0.8400.64
102_L133_L0.8400.64
113_K195_S0.8400.64
37_R108_T0.8360.63
5_I16_Y0.8350.63
34_E64_I0.8340.63
152_A172_G0.8260.62
197_L211_E0.8250.62
96_H143_L0.8240.62
258_Y262_E0.8190.62
8_R172_G0.8150.61
89_C116_F0.8150.61
101_K151_E0.8110.61
37_R40_E0.8110.61
115_I160_P0.8100.61
216_K237_G0.8040.60
74_I111_R0.8010.60
130_V195_S0.7990.60
66_V99_D0.7910.59
170_F202_M0.7910.59
104_D117_Y0.7910.59
218_Q259_T0.7850.58
94_I232_P0.7820.58
177_V188_S0.7790.58
251_N254_K0.7760.57
240_I243_R0.7740.57
35_T40_E0.7740.57
40_E195_S0.7720.57
118_F153_K0.7700.57
179_I183_K0.7680.57
140_R189_L0.7600.56
247_V258_Y0.7480.55
32_I65_R0.7470.55
57_V96_H0.7450.54
183_K189_L0.7430.54
114_V143_L0.7420.54
225_M234_K0.7420.54
236_V246_Q0.7420.54
215_A241_L0.7420.54
186_N242_E0.7380.54
214_T218_Q0.7370.54
105_V243_R0.7340.53
92_K95_E0.7340.53
218_Q260_W0.7310.53
57_V60_L0.7270.53
219_L263_L0.7270.53
134_A150_D0.7270.53
157_G190_N0.7270.53
81_E84_S0.7240.52
103_V154_M0.7230.52
86_F90_Q0.7200.52
92_K136_I0.7170.52
99_D118_F0.7170.52
194_I200_R0.7150.51
219_L241_L0.7130.51
86_F105_V0.7120.51
230_N256_I0.7100.51
117_Y130_V0.7060.50
6_G13_G0.7020.50
211_E215_A0.7000.50
108_T179_I0.6990.50
90_Q93_V0.6960.49
244_V257_E0.6930.49
14_K61_R0.6920.49
151_E195_S0.6920.49
151_E155_L0.6920.49
56_V59_P0.6910.49
90_Q105_V0.6910.49
78_N109_F0.6860.48
83_L87_D0.6840.48
106_E113_K0.6840.48
185_Q208_E0.6840.48
84_S136_I0.6840.48
255_V258_Y0.6830.48
31_V158_I0.6820.48
182_A194_I0.6790.48
128_E132_D0.6770.47
219_L245_L0.6770.47
219_L240_I0.6760.47
79_K221_D0.6730.47
119_T187_L0.6730.47
262_E265_E0.6730.47
197_L202_M0.6670.46
138_K154_M0.6660.46
185_Q201_L0.6660.46
10_K16_Y0.6600.46
164_M170_F0.6590.46
160_P219_L0.6580.46
242_E257_E0.6580.46
75_V105_V0.6570.45
158_I224_E0.6570.45
184_D213_E0.6570.45
170_F261_E0.6560.45
257_E263_L0.6550.45
95_E114_V0.6540.45
130_V148_V0.6530.45
100_M127_R0.6500.45
186_N216_K0.6490.45
211_E240_I0.6490.45
200_R205_L0.6450.44
94_I97_G0.6430.44
240_I250_I0.6410.44
153_K174_F0.6410.44
235_V238_L0.6400.44
82_A157_G0.6340.43
12_A172_G0.6330.43
157_G163_R0.6300.43
14_K18_F0.6300.43
249_L252_R0.6290.43
186_N197_L0.6260.42
6_G16_Y0.6260.42
31_V42_G0.6250.42
70_R73_L0.6250.42
257_E262_E0.6240.42
183_K194_I0.6210.42
18_F109_F0.6210.42
247_V263_L0.6200.42
255_V260_W0.6190.42
30_C75_V0.6180.42
92_K130_V0.6150.41
168_S236_V0.6130.41
85_A107_F0.6120.41
93_V133_L0.6100.41
30_C58_L0.6090.41
49_K52_D0.6080.41
90_Q124_V0.6080.41
211_E241_L0.6010.40
234_K255_V0.6010.40
71_D124_V0.6000.40
51_V97_G0.6000.40
25_I47_A0.5990.40
100_M145_Q0.5970.40
52_D55_D0.5960.40
3_N21_N0.5940.39
192_T213_E0.5920.39
165_L168_S0.5920.39
163_R188_S0.5920.39
87_D131_K0.5910.39
106_E117_Y0.5910.39
5_I46_I0.5900.39
49_K53_E0.5880.39
133_L140_R0.5880.39
142_E189_L0.5860.39
88_I96_H0.5850.38
132_D136_I0.5840.38
109_F177_V0.5840.38
93_V100_M0.5820.38
93_V116_F0.5800.38
10_K13_G0.5790.38
31_V146_I0.5790.38
7_V206_K0.5780.38
152_A157_G0.5750.38
208_E212_Y0.5750.38
177_V210_D0.5750.38
5_I115_I0.5740.37
239_N256_I0.5740.37
83_L124_V0.5730.37
60_L63_V0.5730.37
49_K79_K0.5720.37
176_P180_K0.5710.37
118_F247_V0.5710.37
69_D72_L0.5700.37
5_I25_I0.5670.37
161_C204_C0.5670.37
153_K226_I0.5660.37
224_E237_G0.5650.37
82_A160_P0.5650.37
6_G171_L0.5640.36
20_P51_V0.5620.36
174_F179_I0.5600.36
15_I46_I0.5570.36
94_I222_I0.5550.36
69_D210_D0.5530.35
40_E108_T0.5530.35
15_I18_F0.5520.35
40_E88_I0.5510.35
243_R260_W0.5480.35
18_F63_V0.5470.35
160_P172_G0.5460.35
101_K107_F0.5440.35
30_C74_I0.5360.34
182_A205_L0.5340.34
24_H64_I0.5330.34
10_K207_Y0.5330.34
229_A247_V0.5320.34
143_L164_M0.5320.34
81_E114_V0.5310.33
179_I187_L0.5310.33
22_G70_R0.5300.33
115_I206_K0.5300.33
12_A176_P0.5280.33
31_V120_A0.5260.33
186_N213_E0.5250.33
18_F42_G0.5250.33
90_Q112_N0.5240.33
85_A148_V0.5230.33
126_F131_K0.5230.33
4_V60_L0.5220.33
178_S181_M0.5210.33
116_F134_A0.5210.33
158_I165_L0.5200.32
218_Q254_K0.5200.32
85_A179_I0.5190.32
143_L209_N0.5180.32
74_I248_E0.5170.32
154_M236_V0.5160.32
199_G212_Y0.5150.32
52_D262_E0.5150.32
210_D221_D0.5130.32
140_R144_R0.5130.32
24_H48_N0.5100.32
43_Q62_K0.5100.32
18_F60_L0.5100.32
55_D168_S0.5090.32
86_F219_L0.5080.31
60_L109_F0.5050.31
173_D206_K0.5040.31
119_T122_G0.5020.31
115_I146_I0.5020.31
111_R160_P0.5010.31
39_V90_Q0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qqrA 1 0.36 26.5 0.97 Contact Map
4hczA 1 0.1927 24.6 0.971 Contact Map
3j20N 1 0.2727 23.6 0.971 Contact Map
2lwjA 1 0.2291 19.8 0.972 Contact Map
2ldmA 1 0.2073 17.6 0.973 Contact Map
4qq6A 1 0.1891 17.2 0.973 Contact Map
4kbmB 1 0.2073 16.9 0.973 Contact Map
2xdpA 2 0.3745 16.3 0.973 Contact Map
2x8nA 1 0.2036 15.3 0.973 Contact Map
4a4fA 1 0.2109 14.6 0.974 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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