GREMLIN Database
YAAQ - Uncharacterized protein YaaQ
UniProt: P37538 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 109 (108)
Sequences: 488 (302)
Seq/√Len: 29.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
5_V45_M4.0191.00
52_R55_K3.4221.00
68_D90_E3.3841.00
4_I56_A3.1401.00
5_V101_L2.7911.00
17_L44_F2.7251.00
57_L98_V2.6491.00
50_D102_P2.3740.99
23_H55_K2.1760.98
54_N105_E2.0940.98
12_D67_R2.0680.97
20_L25_F2.0570.97
25_F56_A1.9450.96
54_N58_S1.8810.95
61_K65_Q1.8100.94
10_D42_T1.7940.94
47_G103_V1.7110.92
9_Q16_L1.6610.91
66_K92_E1.6550.91
47_G99_F1.6540.91
27_V44_F1.6090.90
26_R108_Q1.6090.90
17_L27_V1.5930.89
51_I55_K1.5690.89
99_F103_V1.4820.85
48_V56_A1.4820.85
10_D40_G1.4720.85
21_T27_V1.4470.84
8_V44_F1.4280.83
70_M103_V1.4270.83
5_V32_T1.4230.83
20_L56_A1.3280.78
33_T42_T1.3170.78
16_L60_I1.2620.75
102_P105_E1.2330.73
3_L104_D1.2190.72
50_D53_V1.2130.72
33_T40_G1.1980.71
55_K58_S1.1950.71
48_V52_R1.1930.70
9_Q72_A1.1910.70
41_N97_T1.1880.70
76_P86_P1.1410.67
71_I76_P1.1260.66
77_M81_A1.1080.65
78_G108_Q1.0820.63
14_N65_Q1.0720.62
4_I100_V1.0420.60
26_R49_E1.0000.57
20_L84_Y0.9930.56
10_D38_K0.9870.56
23_H89_V0.9860.55
47_G100_V0.9800.55
29_K33_T0.9780.55
75_S81_A0.9580.53
15_R100_V0.9520.53
16_L64_G0.9520.53
5_V47_G0.9430.52
53_V56_A0.9360.52
15_R101_L0.9250.51
98_V105_E0.9220.51
7_V98_V0.9220.51
76_P79_G0.8900.48
48_V55_K0.8880.48
50_D104_D0.8870.48
19_T63_N0.8700.46
13_S33_T0.8670.46
58_S92_E0.8600.46
11_Q108_Q0.8600.46
57_L102_P0.8490.45
98_V107_H0.8430.44
6_A97_T0.8320.44
58_S104_D0.8220.43
75_S79_G0.8210.43
64_G93_V0.8090.42
58_S62_E0.8090.42
32_T48_V0.7890.40
29_K93_V0.7780.39
39_S87_Y0.7730.39
74_V83_S0.7680.39
1_M50_D0.7660.39
8_V16_L0.7610.38
8_V66_K0.7580.38
44_F103_V0.7560.38
26_R87_Y0.7530.38
11_Q83_S0.7500.37
84_Y87_Y0.7500.37
23_H51_I0.7460.37
19_T22_D0.7420.37
25_F48_V0.7350.36
13_S17_L0.7150.35
54_N57_L0.7050.34
24_N52_R0.7020.34
79_G82_D0.7020.34
20_L78_G0.6930.33
57_L60_I0.6890.33
39_S68_D0.6880.33
7_V75_S0.6810.32
29_K40_G0.6790.32
38_K67_R0.6760.32
45_M106_F0.6700.32
76_P90_E0.6680.32
47_G101_L0.6600.31
36_F43_T0.6550.31
8_V25_F0.6410.30
35_G43_T0.6400.30
37_L67_R0.6370.30
63_N74_V0.6300.29
25_F44_F0.6290.29
3_L18_K0.6240.29
31_A44_F0.6220.29
80_N85_V0.6220.29
37_L94_G0.6210.28
27_V73_P0.6160.28
21_T44_F0.6130.28
7_V46_I0.6120.28
13_S44_F0.6090.28
49_E52_R0.6040.27
24_N85_V0.6000.27
81_A104_D0.5950.27
58_S107_H0.5920.27
96_A106_F0.5910.27
64_G79_G0.5870.26
55_K62_E0.5860.26
74_V78_G0.5860.26
11_Q61_K0.5860.26
7_V32_T0.5770.26
21_T108_Q0.5760.26
100_V107_H0.5720.25
61_K68_D0.5690.25
32_T66_K0.5630.25
15_R62_E0.5610.25
104_D107_H0.5600.25
4_I20_L0.5600.25
25_F71_I0.5600.25
49_E56_A0.5590.25
26_R52_R0.5580.25
79_G99_F0.5530.24
70_M78_G0.5520.24
18_K64_G0.5510.24
74_V80_N0.5490.24
18_K58_S0.5410.24
49_E62_E0.5380.24
21_T60_I0.5380.24
17_L76_P0.5370.23
10_D64_G0.5370.23
46_I53_V0.5370.23
64_G94_G0.5320.23
2_K61_K0.5320.23
11_Q82_D0.5300.23
5_V26_R0.5220.23
38_K47_G0.5180.22
49_E59_L0.5120.22
69_Q107_H0.5120.22
47_G56_A0.5110.22
58_S61_K0.5100.22
73_P98_V0.5090.22
11_Q21_T0.5070.22
13_S39_S0.5050.22
66_K71_I0.5010.21
10_D72_A0.5000.21
37_L88_P0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rleA 3 1 100 0.081 Contact Map
3m05A 3 0.8899 100 0.293 Contact Map
4rwwA 3 1 100 0.297 Contact Map
4wk1A 3 0.7706 100 0.309 Contact Map
2o66A 5 0.7523 99.4 0.67 Contact Map
4ozjA 3 0.7523 99.4 0.68 Contact Map
3t9zA 3 0.7523 99.4 0.681 Contact Map
1vfjA 3 0.7798 99.3 0.693 Contact Map
1hwuA 6 0.7523 99.3 0.697 Contact Map
3bzqA 3 0.7523 99.3 0.697 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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