GREMLIN Database
YAAB - Uncharacterized protein YaaB
UniProt: P37525 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 81 (76)
Sequences: 240 (171)
Seq/√Len: 19.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
7_D63_P3.3661.00
5_L44_S2.8910.99
22_F52_I2.7520.98
3_I13_T2.5790.98
55_T63_P2.5360.97
2_Y65_S2.0470.91
32_E47_G2.0340.91
71_K74_Q1.8850.87
26_M61_Y1.7100.82
35_K59_I1.7060.82
28_P61_Y1.6320.78
19_I69_L1.5880.77
60_Y63_P1.5260.74
33_F39_H1.4880.72
4_H62_S1.4870.72
30_V37_Q1.4500.70
9_F46_N1.4440.69
7_D44_S1.4100.67
29_I32_E1.3790.66
12_S39_H1.3360.63
54_V58_N1.2970.61
10_V75_F1.2630.59
16_I43_P1.2350.57
53_V71_K1.2250.56
3_I73_A1.2010.55
15_D71_K1.1870.54
4_H69_L1.1850.54
8_D45_V1.1760.53
5_L11_V1.1620.52
2_Y45_V1.1610.52
8_D17_V1.1070.49
15_D57_Q1.1030.48
13_T66_S1.0940.48
8_D73_A1.0640.46
18_G63_P1.0550.45
2_Y67_S1.0500.45
17_V57_Q1.0410.44
47_G60_Y1.0340.44
10_V27_S1.0200.43
67_S71_K1.0170.43
3_I70_K0.9850.41
19_I66_S0.9770.40
36_K40_K0.9730.40
42_V58_N0.9660.40
4_H55_T0.9550.39
49_P61_Y0.9460.39
16_I67_S0.9340.38
17_V34_L0.9300.38
55_T62_S0.9240.37
44_S64_L0.9230.37
16_I32_E0.9190.37
44_S63_P0.9190.37
49_P52_I0.9090.36
52_I61_Y0.9060.36
23_K34_L0.8830.35
15_D58_N0.8770.34
20_F63_P0.8730.34
55_T60_Y0.8610.34
23_K48_T0.8530.33
48_T64_L0.8490.33
13_T16_I0.8470.33
3_I69_L0.8200.31
18_G55_T0.8190.31
3_I57_Q0.8070.30
15_D48_T0.8020.30
20_F52_I0.7980.30
35_K47_G0.7910.30
16_I48_T0.7750.29
33_F66_S0.7680.28
5_L45_V0.7660.28
23_K30_V0.7640.28
22_F71_K0.7420.27
24_A63_P0.7350.27
40_K56_V0.7340.27
12_S16_I0.7320.27
47_G61_Y0.7020.25
14_R30_V0.6920.25
4_H65_S0.6860.24
34_L61_Y0.6740.24
3_I12_S0.6720.24
5_L60_Y0.6640.23
28_P46_N0.6610.23
18_G41_V0.6580.23
10_V59_I0.6580.23
41_V54_V0.6510.23
28_P45_V0.6390.22
7_D73_A0.6190.21
33_F64_L0.6180.21
48_T61_Y0.6100.21
43_P67_S0.6080.21
7_D64_L0.6000.20
36_K39_H0.5970.20
43_P61_Y0.5950.20
31_E37_Q0.5910.20
2_Y29_I0.5900.20
22_F49_P0.5840.20
7_D61_Y0.5820.20
27_S65_S0.5780.20
27_S60_Y0.5700.19
25_N49_P0.5610.19
30_V41_V0.5590.19
30_V34_L0.5550.19
16_I52_I0.5520.19
8_D57_Q0.5440.18
67_S75_F0.5370.18
36_K56_V0.5290.18
42_V57_Q0.5240.17
23_K49_P0.5160.17
32_E40_K0.5130.17
16_I24_A0.5110.17
18_G52_I0.5060.17
16_I58_N0.5050.17
40_K45_V0.5040.17
10_V23_K0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3sooA 2 0.3827 11.5 0.919 Contact Map
4yivA 1 0.9877 8.6 0.924 Contact Map
2jrbA 1 0.2222 6.9 0.927 Contact Map
2ykoA 3 0.9259 5.9 0.929 Contact Map
2kkuA 1 0.9259 5.1 0.931 Contact Map
2x2zA 1 0.9877 4.5 0.933 Contact Map
3pg7A 1 0.9753 4.3 0.934 Contact Map
4apmA 1 0.8395 4.2 0.934 Contact Map
4nexA 2 0.2222 4.1 0.934 Contact Map
4xttA 2 0.4074 3.9 0.935 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0051 seconds.