YYAE - BACSU - GREMLIN Contacts

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YYAE - Probable oxidoreductase YyaE

UniProt:	P37519	Sequences: MSKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKICGRGRMLETKTNSPDRLRYPMKKQNGEFVRISWEQALDEIADKLREIKETSETTAVLHSHDYANNGLLKALDQRFFNGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNSKHVVVWGRNVSRTNMHLYHHLQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISEHSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGGANFGNVQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVLTAADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAIDSIMTDTAELCDYVLPTATVFEEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGLSSLEAEDVTLERLKEKGHLPLPVKQVPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNVPEESVFHNEELAGKYPYTLLSIHPQRSNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSVNALTNDTNSDNGMGSTLFDCLVGLKKA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	667 (636)
Sequences:	9787 (5965)
Seq/√Len:	236.5

ECOLI - YNFE YNFF DMSA TORZ FDHF BISC TORA NAPA YDEP FDNG FDOG NUOG
BACSU - YYAE NASC YOAE YJGC FDHL
HALSA - DMSA
SULSO - Q97ZA1 Q97XX8 Q97V13

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
63_Y	74_R	5.571	1.00
596_L	615_V	4.415	1.00
82_D	461_R	4.260	1.00
603_V	665_K	3.988	1.00
449_K	457_E	3.628	1.00
603_V	610_S	3.355	1.00
230_M	276_G	3.324	1.00
258_E	268_M	3.184	1.00
87_K	90_E	3.180	1.00
590_I	624_K	3.168	1.00
222_A	260_F	3.152	1.00
557_Y	594_Q	3.130	1.00
453_W	457_E	3.111	1.00
440_K	443_E	2.980	1.00
235_E	239_S	2.940	1.00
589_D	623_A	2.927	1.00
226_V	230_M	2.900	1.00
225_K	229_E	2.895	1.00
83_E	412_Y	2.802	1.00
398_A	410_C	2.735	1.00
166_W	220_A	2.731	1.00
224_L	248_V	2.723	1.00
76_S	79_Q	2.685	1.00
261_I	268_M	2.675	1.00
605_F	665_K	2.668	1.00
84_I	412_Y	2.651	1.00
81_L	461_R	2.624	1.00
243_V	517_S	2.614	1.00
605_F	663_G	2.611	1.00
90_E	94_T	2.560	1.00
190_T	277_L	2.553	1.00
517_S	521_E	2.507	1.00
268_M	272_E	2.497	1.00
224_L	310_A	2.490	1.00
207_R	273_Y	2.486	1.00
270_E	273_Y	2.480	1.00
91_I	99_A	2.474	1.00
606_N	662_V	2.473	1.00
219_L	264_T	2.469	1.00
267_S	270_E	2.454	1.00
193_V	205_A	2.446	1.00
161_K	282_P	2.436	1.00
591_A	617_V	2.433	1.00
63_Y	447_E	2.417	1.00
602_V	615_V	2.404	1.00
586_I	664_L	2.401	1.00
66_K	83_E	2.400	1.00
75_I	412_Y	2.398	1.00
256_S	259_E	2.377	1.00
231_G	235_E	2.344	1.00
586_I	615_V	2.336	1.00
81_L	457_E	2.334	1.00
581_H	614_K	2.323	1.00
605_F	610_S	2.312	1.00
593_G	623_A	2.308	1.00
233_T	238_I	2.301	1.00
66_K	412_Y	2.289	1.00
66_K	75_I	2.273	1.00
228_I	245_F	2.228	1.00
159_N	317_K	2.215	1.00
88_L	368_M	2.140	1.00
367_E	394_P	2.128	1.00
236_T	240_E	2.117	1.00
382_N	646_D	2.099	1.00
594_Q	663_G	2.096	1.00
598_D	617_V	2.090	1.00
162_H	277_L	2.081	1.00
160_S	163_V	2.070	1.00
84_I	397_V	2.060	1.00
209_I	274_L	2.050	1.00
457_E	461_R	2.030	1.00
584_V	626_I	2.025	1.00
596_L	602_V	1.977	1.00
83_E	87_K	1.976	1.00
273_Y	277_L	1.947	1.00
601_E	612_K	1.923	1.00
91_I	368_M	1.910	1.00
209_I	266_T	1.908	1.00
445_Q	448_A	1.903	1.00
603_V	612_K	1.899	1.00
584_V	604_I	1.897	1.00
584_V	602_V	1.897	1.00
219_L	271_L	1.883	1.00
184_V	189_A	1.880	1.00
74_R	447_E	1.870	1.00
162_H	192_T	1.864	1.00
75_I	83_E	1.861	1.00
207_R	270_E	1.850	1.00
489_T	492_R	1.848	1.00
370_I	399_I	1.833	1.00
225_K	257_L	1.832	1.00
20_L	35_P	1.815	1.00
584_V	628_I	1.810	1.00
598_D	616_K	1.807	1.00
233_T	245_F	1.805	1.00
613_G	628_I	1.802	1.00
557_Y	626_I	1.789	1.00
228_I	249_K	1.787	1.00
66_K	73_V	1.786	1.00
586_I	626_I	1.771	1.00
316_I	319_G	1.764	1.00
185_K	206_D	1.763	1.00
589_D	592_A	1.745	1.00
403_M	407_A	1.744	1.00
597_Q	600_D	1.733	1.00
215_M	263_K	1.713	1.00
626_I	662_V	1.696	1.00
82_D	86_D	1.685	1.00
226_V	272_E	1.662	1.00
230_M	272_E	1.662	1.00
278_Y	283_V	1.659	1.00
232_R	279_A	1.646	1.00
207_R	277_L	1.645	1.00
423_E	440_K	1.642	1.00
226_V	276_G	1.639	1.00
161_K	281_G	1.636	1.00
492_R	496_K	1.620	1.00
194_I	219_L	1.619	1.00
276_G	280_D	1.611	1.00
601_E	614_K	1.606	1.00
278_Y	311_S	1.605	1.00
393_V	396_T	1.597	1.00
62_R	446_G	1.597	1.00
250_E	253_K	1.593	1.00
99_A	367_E	1.591	1.00
261_I	267_S	1.581	1.00
260_F	271_L	1.580	1.00
228_I	252_L	1.575	1.00
457_E	460_K	1.566	1.00
65_M	413_V	1.562	1.00
238_I	245_F	1.552	1.00
18_G	37_H	1.539	1.00
226_V	257_L	1.537	1.00
562_I	627_N	1.533	1.00
227_L	279_A	1.526	1.00
261_I	271_L	1.520	1.00
227_L	233_T	1.513	1.00
75_I	79_Q	1.512	1.00
232_R	276_G	1.505	1.00
219_L	274_L	1.487	1.00
244_G	247_D	1.478	1.00
242_S	522_F	1.477	1.00
585_D	618_M	1.474	1.00
164_V	274_L	1.462	1.00
164_V	194_I	1.462	1.00
395_M	412_Y	1.456	1.00
258_E	272_E	1.455	1.00
84_I	414_L	1.447	1.00
218_W	263_K	1.442	1.00
86_D	90_E	1.441	1.00
79_Q	83_E	1.438	1.00
89_R	93_E	1.438	1.00
417_A	450_S	1.437	1.00
22_T	32_D	1.427	1.00
387_R	391_E	1.426	1.00
247_D	250_E	1.420	1.00
101_L	366_I	1.398	1.00
243_V	521_E	1.397	1.00
53_T	575_F	1.394	1.00
504_K	508_W	1.384	1.00
229_E	253_K	1.379	1.00
611_M	628_I	1.373	1.00
193_V	202_A	1.371	1.00
557_Y	590_I	1.369	1.00
473_Q	477_E	1.369	1.00
64_P	77_W	1.362	1.00
65_M	74_R	1.358	1.00
291_M	304_I	1.357	1.00
388_Q	391_E	1.356	1.00
162_H	274_L	1.352	1.00
88_L	397_V	1.347	1.00
215_M	264_T	1.345	1.00
95_S	367_E	1.343	1.00
7_S	21_V	1.343	1.00
226_V	229_E	1.343	1.00
259_E	262_V	1.334	1.00
207_R	274_L	1.332	1.00
588_P	619_K	1.329	1.00
223_V	278_Y	1.329	1.00
102_H	120_F	1.326	1.00
183_Q	186_K	1.321	1.00
398_A	407_A	1.319	1.00
223_V	274_L	1.318	1.00
236_T	239_S	1.312	1.00
515_T	521_E	1.311	1.00
401_S	418_T	1.311	1.00
310_A	522_F	1.309	1.00
552_A	607_D	1.308	1.00
371_V	396_T	1.307	1.00
403_M	413_V	1.307	1.00
362_A	385_K	1.299	1.00
245_F	249_K	1.297	1.00
471_S	474_E	1.296	1.00
594_Q	664_L	1.292	1.00
196_P	208_Y	1.287	1.00
353_T	356_E	1.286	1.00
449_K	453_W	1.285	1.00
209_I	270_E	1.275	1.00
21_V	28_V	1.272	1.00
474_E	477_E	1.268	1.00
229_E	272_E	1.265	1.00
83_E	395_M	1.263	1.00
198_F	203_K	1.260	1.00
557_Y	663_G	1.256	1.00
439_K	494_K	1.250	1.00
587_S	623_A	1.243	1.00
223_V	275_A	1.239	1.00
265_E	622_H	1.234	1.00
450_S	453_W	1.229	1.00
226_V	232_R	1.228	1.00
584_V	613_G	1.223	1.00
313_N	319_G	1.223	1.00
399_I	454_I	1.220	1.00
255_V	263_K	1.219	1.00
460_K	465_G	1.218	1.00
211_V	266_T	1.217	1.00
255_V	259_E	1.211	1.00
21_V	31_V	1.210	1.00
477_E	480_L	1.202	1.00
583_Q	616_K	1.201	1.00
255_V	260_F	1.197	1.00
85_A	461_R	1.196	1.00
81_L	449_K	1.194	1.00
399_I	416_T	1.193	1.00
68_Q	73_V	1.189	1.00
490_L	494_K	1.187	1.00
28_V	55_T	1.184	1.00
89_R	92_K	1.183	1.00
211_V	215_M	1.178	1.00
385_K	388_Q	1.173	1.00
628_I	640_V	1.173	1.00
225_K	253_K	1.171	1.00
20_L	34_D	1.166	1.00
92_K	100_V	1.161	1.00
20_L	32_D	1.158	1.00
156_D	159_N	1.155	1.00
382_N	385_K	1.152	1.00
359_L	385_K	1.149	1.00
224_L	252_L	1.148	1.00
585_D	616_K	1.147	1.00
226_V	271_L	1.147	1.00
372_T	455_W	1.144	1.00
254_T	259_E	1.142	1.00
228_I	233_T	1.142	1.00
476_L	480_L	1.141	1.00
491_E	495_E	1.138	1.00
79_Q	412_Y	1.134	1.00
554_K	663_G	1.133	1.00
100_V	368_M	1.133	1.00
141_A	301_I	1.131	1.00
453_W	460_K	1.131	1.00
235_E	249_K	1.129	1.00
618_M	621_A	1.128	1.00
368_M	395_M	1.126	1.00
140_E	651_N	1.123	1.00
223_V	227_L	1.118	1.00
220_A	304_I	1.113	1.00
232_R	280_D	1.110	1.00
190_T	206_D	1.108	1.00
192_T	274_L	1.107	1.00
163_V	181_L	1.107	1.00
554_K	607_D	1.105	1.00
417_A	448_A	1.102	1.00
269_E	272_E	1.097	1.00
162_H	281_G	1.095	1.00
238_I	522_F	1.094	1.00
245_F	310_A	1.088	1.00
162_H	283_V	1.081	1.00
198_F	620_Q	1.075	1.00
388_Q	392_K	1.074	1.00
227_L	311_S	1.070	1.00
164_V	223_V	1.070	1.00
165_V	168_R	1.070	1.00
67_K	72_F	1.069	1.00
87_K	394_P	1.067	1.00
222_A	271_L	1.054	1.00
163_V	189_A	1.053	1.00
203_K	620_Q	1.048	1.00
223_V	307_L	1.045	1.00
157_I	284_S	1.045	1.00
261_I	264_T	1.044	1.00
92_K	97_T	1.042	1.00
414_L	454_I	1.040	1.00
163_V	184_V	1.039	1.00
27_K	56_N	1.038	1.00
586_I	596_L	1.037	1.00
242_S	309_A	1.037	1.00
120_F	126_V	1.037	1.00
362_A	388_Q	1.036	1.00
166_W	194_I	1.033	1.00
368_M	397_V	1.032	1.00
91_I	395_M	1.031	1.00
424_D	427_Y	1.026	1.00
377_L	383_T	1.023	1.00
246_D	249_K	1.022	1.00
352_M	360_T	1.020	1.00
91_I	394_P	1.017	1.00
604_I	628_I	1.015	1.00
285_T	308_V	1.012	1.00
559_L	662_V	1.011	1.00
260_F	264_T	1.010	1.00
355_A	358_V	1.002	1.00
357_E	361_A	1.000	1.00
161_K	187_K	0.999	1.00
356_E	360_T	0.997	1.00
68_Q	71_E	0.997	1.00
261_I	269_E	0.997	1.00
158_Y	180_H	0.996	1.00
371_V	406_T	0.992	1.00
220_A	303_W	0.990	1.00
278_Y	285_T	0.988	1.00
31_V	52_E	0.987	1.00
587_S	621_A	0.986	1.00
88_L	462_L	0.986	1.00
309_A	520_F	0.985	1.00
356_E	359_L	0.979	1.00
560_L	625_T	0.976	1.00
194_I	209_I	0.975	1.00
370_I	458_L	0.973	1.00
490_L	493_L	0.972	1.00
33_G	42_G	0.971	1.00
213_P	625_T	0.969	1.00
248_V	310_A	0.969	1.00
556_P	663_G	0.969	1.00
22_T	30_K	0.967	1.00
55_T	442_V	0.966	1.00
194_I	274_L	0.966	1.00
604_I	662_V	0.965	1.00
248_V	252_L	0.964	1.00
437_Y	494_K	0.962	1.00
273_Y	276_G	0.961	1.00
87_K	91_I	0.959	1.00
626_I	664_L	0.957	1.00
423_E	437_Y	0.957	1.00
62_R	445_Q	0.954	1.00
283_V	313_N	0.953	1.00
73_V	79_Q	0.952	1.00
360_T	365_A	0.951	1.00
249_K	253_K	0.951	1.00
417_A	444_P	0.951	1.00
226_V	275_A	0.951	1.00
18_G	34_D	0.949	1.00
165_V	191_I	0.949	1.00
555_Y	663_G	0.949	1.00
585_D	620_Q	0.948	1.00
170_V	181_L	0.945	1.00
513_F	520_F	0.944	1.00
217_G	300_T	0.944	1.00
96_E	99_A	0.941	1.00
101_L	357_E	0.937	1.00
588_P	592_A	0.936	1.00
81_L	453_W	0.934	1.00
77_W	414_L	0.933	1.00
492_R	495_E	0.930	1.00
225_K	256_S	0.929	1.00
243_V	519_K	0.928	1.00
416_T	454_I	0.928	1.00
420_F	441_L	0.926	1.00
424_D	429_S	0.926	1.00
341_E	345_T	0.926	1.00
586_I	591_A	0.926	1.00
78_E	461_R	0.924	1.00
194_I	211_V	0.924	1.00
272_E	276_G	0.922	1.00
256_S	260_F	0.922	1.00
259_E	263_K	0.921	1.00
192_T	277_L	0.921	1.00
225_K	252_L	0.917	1.00
282_P	316_I	0.917	1.00
185_K	204_L	0.917	1.00
469_E	472_T	0.916	1.00
84_I	395_M	0.916	1.00
233_T	310_A	0.913	1.00
61_L	413_V	0.912	1.00
196_P	210_S	0.911	1.00
212_K	622_H	0.911	1.00
190_T	207_R	0.910	1.00
85_A	89_R	0.909	1.00
590_I	623_A	0.909	1.00
88_L	123_Y	0.907	1.00
77_W	454_I	0.904	1.00
377_L	387_R	0.902	1.00
66_K	79_Q	0.901	1.00
62_R	74_R	0.894	0.99
248_V	522_F	0.893	0.99
268_M	271_L	0.893	0.99
266_T	271_L	0.893	0.99
234_D	316_I	0.892	0.99
221_A	255_V	0.889	0.99
478_M	482_S	0.888	0.99
158_Y	183_Q	0.886	0.99
266_T	270_E	0.886	0.99
24_D	29_T	0.885	0.99
251_L	254_T	0.883	0.99
257_L	272_E	0.883	0.99
557_Y	664_L	0.882	0.99
555_Y	606_N	0.881	0.99
573_V	576_I	0.879	0.99
227_L	307_L	0.879	0.99
211_V	219_L	0.878	0.99
124_G	128_E	0.878	0.99
552_A	661_L	0.875	0.99
584_V	664_L	0.874	0.99
407_A	413_V	0.871	0.99
185_K	191_I	0.870	0.99
257_L	260_F	0.870	0.99
360_T	363_D	0.868	0.99
354_Q	358_V	0.868	0.99
340_P	344_T	0.867	0.99
473_Q	490_L	0.865	0.99
357_E	366_I	0.862	0.99
269_E	273_Y	0.862	0.99
164_V	285_T	0.861	0.99
509_D	512_Q	0.860	0.99
21_V	420_F	0.858	0.99
224_L	307_L	0.858	0.99
182_Q	185_K	0.856	0.99
124_G	129_I	0.856	0.99
477_E	481_S	0.855	0.99
338_T	343_K	0.854	0.99
222_A	226_V	0.854	0.99
81_L	458_L	0.853	0.99
72_F	413_V	0.851	0.99
63_Y	76_S	0.850	0.99
611_M	643_L	0.849	0.99
589_D	619_K	0.849	0.99
84_I	458_L	0.848	0.99
282_P	319_G	0.847	0.99
165_V	201_T	0.847	0.99
145_D	302_R	0.844	0.99
218_W	222_A	0.843	0.99
221_A	251_L	0.841	0.99
477_E	491_E	0.841	0.99
391_E	409_L	0.837	0.99
19_F	44_I	0.836	0.99
64_P	76_S	0.835	0.99
384_N	388_Q	0.835	0.99
88_L	370_I	0.834	0.99
24_D	27_K	0.831	0.99
306_A	522_F	0.829	0.99
449_K	454_I	0.829	0.99
84_I	87_K	0.825	0.99
591_A	596_L	0.825	0.99
622_H	625_T	0.825	0.99
472_T	478_M	0.824	0.99
587_S	617_V	0.820	0.99
65_M	403_M	0.817	0.99
257_L	261_I	0.817	0.99
192_T	207_R	0.816	0.99
246_D	250_E	0.815	0.99
586_I	602_V	0.811	0.99
460_K	471_S	0.810	0.99
369_I	393_V	0.809	0.99
171_S	201_T	0.809	0.99
162_H	190_T	0.809	0.99
505_Q	508_W	0.807	0.99
119_F	458_L	0.806	0.99
195_D	199_N	0.806	0.99
291_M	300_T	0.805	0.99
519_K	524_S	0.804	0.99
220_A	307_L	0.804	0.99
340_P	343_K	0.804	0.99
221_A	252_L	0.803	0.99
119_F	462_L	0.803	0.99
551_L	661_L	0.802	0.99
83_E	86_D	0.801	0.99
226_V	268_M	0.801	0.99
552_A	556_P	0.798	0.99
499_L	503_V	0.797	0.99
198_F	210_S	0.796	0.99
211_V	264_T	0.793	0.99
103_S	106_Y	0.793	0.99
613_G	640_V	0.790	0.99
92_K	123_Y	0.789	0.99
183_Q	187_K	0.789	0.99
219_L	223_V	0.788	0.99
144_W	651_N	0.786	0.99
119_F	455_W	0.785	0.99
476_L	479_G	0.785	0.99
77_W	449_K	0.784	0.99
289_L	293_R	0.783	0.99
210_S	622_H	0.782	0.99
425_I	428_S	0.781	0.99
404_T	407_A	0.781	0.99
198_F	619_K	0.781	0.99
88_L	92_K	0.781	0.99
423_E	473_Q	0.779	0.99
232_R	253_K	0.778	0.99
277_L	281_G	0.778	0.99
229_E	257_L	0.778	0.99
521_E	524_S	0.777	0.99
353_T	653_M	0.776	0.99
8_A	436_Q	0.774	0.99
55_T	418_T	0.772	0.99
144_W	302_R	0.770	0.98
524_S	527_A	0.770	0.98
608_R	660_C	0.770	0.98
100_V	123_Y	0.770	0.98
270_E	277_L	0.768	0.98
456_S	460_K	0.768	0.98
87_K	395_M	0.767	0.98
285_T	304_I	0.765	0.98
384_N	642_A	0.764	0.98
251_L	255_V	0.763	0.98
212_K	265_E	0.762	0.98
375_N	570_S	0.760	0.98
520_F	527_A	0.759	0.98
125_G	128_E	0.758	0.98
608_R	644_T	0.758	0.98
13_C	17_C	0.756	0.98
367_E	393_V	0.755	0.98
9_C	17_C	0.755	0.98
339_L	342_L	0.754	0.98
473_Q	480_L	0.754	0.98
504_K	507_P	0.753	0.98
352_M	355_A	0.753	0.98
162_H	278_Y	0.751	0.98
426_Y	429_S	0.750	0.98
222_A	257_L	0.750	0.98
371_V	398_A	0.749	0.98
516_P	521_E	0.746	0.98
423_E	439_K	0.746	0.98
342_L	346_S	0.745	0.98
552_A	555_Y	0.744	0.98
351_M	355_A	0.742	0.98
62_R	65_M	0.742	0.98
238_I	242_S	0.739	0.98
217_G	303_W	0.737	0.98
9_C	13_C	0.737	0.98
453_W	456_S	0.737	0.98
592_A	597_Q	0.736	0.98
261_I	266_T	0.736	0.98
209_I	219_L	0.735	0.98
352_M	357_E	0.735	0.98
442_V	445_Q	0.731	0.98
156_D	318_G	0.731	0.98
361_A	393_V	0.730	0.98
589_D	593_G	0.730	0.98
604_I	613_G	0.729	0.98
37_H	40_T	0.729	0.98
104_H	129_I	0.728	0.98
152_H	156_D	0.727	0.98
75_I	80_A	0.727	0.98
282_P	317_K	0.727	0.98
607_D	661_L	0.727	0.98
418_T	445_Q	0.726	0.98
227_L	231_G	0.726	0.98
222_A	259_E	0.725	0.98
57_S	402_I	0.723	0.98
656_T	659_D	0.723	0.98
141_A	305_D	0.722	0.98
375_N	406_T	0.722	0.98
465_G	468_F	0.718	0.98
468_F	471_S	0.717	0.98
86_D	89_R	0.717	0.98
591_A	618_M	0.717	0.98
153_G	500_P	0.716	0.98
230_M	279_A	0.716	0.98
257_L	268_M	0.716	0.98
87_K	368_M	0.715	0.98
518_G	524_S	0.715	0.98
146_F	305_D	0.713	0.98
377_L	409_L	0.712	0.97
33_G	44_I	0.711	0.97
434_Y	500_P	0.710	0.97
276_G	279_A	0.710	0.97
473_Q	494_K	0.709	0.97
519_K	522_F	0.706	0.97
118_R	121_N	0.704	0.97
238_I	310_A	0.703	0.97
202_A	208_Y	0.703	0.97
67_K	70_G	0.703	0.97
362_A	392_K	0.703	0.97
405_D	633_W	0.701	0.97
85_A	462_L	0.701	0.97
338_T	341_E	0.701	0.97
248_V	251_L	0.701	0.97
368_M	412_Y	0.700	0.97
81_L	85_A	0.700	0.97
513_F	517_S	0.700	0.97
222_A	256_S	0.700	0.97
596_L	617_V	0.697	0.97
559_L	628_I	0.696	0.97
586_I	617_V	0.694	0.97
119_F	124_G	0.692	0.97
295_K	656_T	0.692	0.97
424_D	428_S	0.691	0.97
496_K	499_L	0.688	0.97
81_L	84_I	0.688	0.97
81_L	454_I	0.688	0.97
184_V	187_K	0.688	0.97
217_G	296_N	0.688	0.97
384_N	387_R	0.687	0.97
56_N	445_Q	0.685	0.97
21_V	441_L	0.685	0.97
222_A	262_V	0.684	0.97
361_A	364_P	0.683	0.97
89_R	462_L	0.683	0.97
337_L	341_E	0.682	0.97
101_L	369_I	0.682	0.97
596_L	600_D	0.680	0.97
95_S	99_A	0.680	0.97
108_N	372_T	0.676	0.97
119_F	459_A	0.676	0.97
475_F	478_M	0.676	0.97
611_M	640_V	0.674	0.97
120_F	125_G	0.674	0.97
337_L	340_P	0.673	0.96
172_R	200_P	0.671	0.96
377_L	390_F	0.669	0.96
274_L	277_L	0.668	0.96
15_D	176_H	0.667	0.96
400_D	413_V	0.667	0.96
190_T	273_Y	0.666	0.96
91_I	367_E	0.666	0.96
557_Y	624_K	0.665	0.96
299_G	302_R	0.664	0.96
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493_L	498_H	0.662	0.96
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142_Q	305_D	0.659	0.96
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258_E	261_I	0.657	0.96
400_D	404_T	0.656	0.96
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41_E	183_Q	0.656	0.96
582_V	632_M	0.655	0.96
197_I	585_D	0.654	0.96
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141_A	145_D	0.642	0.95
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517_S	524_S	0.638	0.95
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157_I	286_F	0.632	0.95
210_S	213_P	0.631	0.95
440_K	444_P	0.628	0.95
342_L	345_T	0.628	0.95
158_Y	187_K	0.628	0.95
56_N	442_V	0.626	0.95
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493_L	496_K	0.625	0.95
489_T	493_L	0.624	0.95
64_P	454_I	0.624	0.95
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482_S	485_A	0.622	0.95
338_T	342_L	0.621	0.95
126_V	129_I	0.619	0.94
197_I	627_N	0.618	0.94
224_L	306_A	0.618	0.94
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239_S	246_D	0.617	0.94
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222_A	268_M	0.616	0.94
564_P	583_Q	0.616	0.94
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308_V	321_A	0.615	0.94
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369_I	396_T	0.614	0.94
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359_L	363_D	0.613	0.94
278_Y	308_V	0.613	0.94
228_I	310_A	0.612	0.94
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338_T	345_T	0.611	0.94
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122_G	464_F	0.611	0.94
104_H	107_A	0.611	0.94
417_A	422_E	0.611	0.94
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465_G	469_E	0.608	0.94
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145_D	305_D	0.608	0.94
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371_V	376_P	0.592	0.93
523_T	528_E	0.590	0.93
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508_W	511_Y	0.589	0.93
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229_E	249_K	0.588	0.93
649_S	652_G	0.587	0.93
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322_N	325_N	0.587	0.93
70_G	73_V	0.587	0.93
282_P	313_N	0.586	0.93
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63_Y	75_I	0.585	0.93
146_F	321_A	0.585	0.93
300_T	304_I	0.585	0.93
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227_L	232_R	0.584	0.93
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124_G	127_T	0.583	0.93
514_L	517_S	0.583	0.93
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549_E	607_D	0.582	0.92
481_S	484_E	0.581	0.92
65_M	72_F	0.581	0.92
336_K	343_K	0.581	0.92
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479_G	482_S	0.579	0.92
336_K	339_L	0.579	0.92
645_N	660_C	0.579	0.92
523_T	526_L	0.578	0.92
343_K	349_F	0.578	0.92
46_G	565_Q	0.578	0.92
379_Q	570_S	0.577	0.92
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9_C	48_G	0.575	0.92
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210_S	270_E	0.574	0.92
549_E	608_R	0.573	0.92
68_Q	72_F	0.573	0.92
269_E	276_G	0.572	0.92
390_F	396_T	0.572	0.92
520_F	523_T	0.572	0.92
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225_K	254_T	0.571	0.92
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108_N	112_L	0.570	0.92
215_M	218_W	0.570	0.92
291_M	301_I	0.570	0.92
234_D	237_F	0.569	0.92
164_V	283_V	0.567	0.91
470_Y	475_F	0.567	0.91
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468_F	472_T	0.565	0.91
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515_T	520_F	0.564	0.91
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583_Q	629_D	0.562	0.91
467_L	470_Y	0.562	0.91
195_D	202_A	0.562	0.91
112_L	115_L	0.561	0.91
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330_E	335_T	0.558	0.91
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520_F	524_S	0.557	0.91
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587_S	590_I	0.555	0.91
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546_F	550_E	0.554	0.90
298_G	651_N	0.554	0.90
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555_Y	607_D	0.545	0.90
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181_L	191_I	0.540	0.89
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600_D	615_V	0.538	0.89
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567_S	571_Q	0.538	0.89
341_E	344_T	0.538	0.89
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563_H	569_H	0.537	0.89
117_Q	121_N	0.537	0.89
459_A	463_G	0.537	0.89
492_R	499_L	0.537	0.89
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564_P	580_Q	0.536	0.89
270_E	274_L	0.535	0.89
518_G	522_F	0.535	0.89
396_T	410_C	0.535	0.89
330_E	333_A	0.534	0.89
421_E	445_Q	0.534	0.89
112_L	422_E	0.534	0.89
518_G	527_A	0.534	0.89
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294_Y	659_D	0.533	0.89
456_S	465_G	0.533	0.89
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322_N	327_Q	0.532	0.89
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377_L	406_T	0.528	0.88
53_T	573_V	0.528	0.88
180_H	183_Q	0.528	0.88
601_E	615_V	0.527	0.88
383_T	387_R	0.527	0.88
249_K	252_L	0.526	0.88
558_T	659_D	0.525	0.88
138_G	301_I	0.525	0.88
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617_V	620_Q	0.524	0.88
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352_M	356_E	0.523	0.88
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354_Q	357_E	0.523	0.88
45_C	48_G	0.522	0.88
590_I	594_Q	0.522	0.88
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368_M	393_V	0.521	0.88
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588_P	617_V	0.518	0.87
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242_S	245_F	0.517	0.87
630_E	637_G	0.515	0.87
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401_S	416_T	0.514	0.87
142_Q	321_A	0.514	0.87
396_T	406_T	0.513	0.87
136_G	654_G	0.513	0.87
221_A	248_V	0.513	0.87
370_I	455_W	0.513	0.87
374_G	380_V	0.512	0.87
61_L	403_M	0.512	0.87
352_M	361_A	0.511	0.87
223_V	276_G	0.510	0.87
94_T	394_P	0.510	0.87
387_R	409_L	0.510	0.87
104_H	108_N	0.510	0.87
563_H	630_E	0.510	0.87
295_K	647_T	0.509	0.86
98_T	127_T	0.509	0.86
503_V	508_W	0.508	0.86
36_N	41_E	0.508	0.86
345_T	349_F	0.508	0.86
132_S	136_G	0.508	0.86
152_H	284_S	0.507	0.86
140_E	652_G	0.507	0.86
227_L	280_D	0.507	0.86
514_L	519_K	0.507	0.86
17_C	48_G	0.507	0.86
102_H	116_D	0.507	0.86
610_S	665_K	0.506	0.86
575_F	579_L	0.506	0.86
466_E	469_E	0.505	0.86
594_Q	626_I	0.504	0.86
75_I	395_M	0.504	0.86
350_S	353_T	0.503	0.86
19_F	51_L	0.503	0.86
55_T	420_F	0.503	0.86
73_V	83_E	0.503	0.86
212_K	558_T	0.502	0.86
23_V	26_G	0.502	0.86
102_H	124_G	0.502	0.86
519_K	527_A	0.502	0.86
358_V	389_A	0.502	0.86
195_D	208_Y	0.501	0.86
648_N	653_M	0.501	0.86
230_M	257_L	0.501	0.86
160_S	283_V	0.501	0.86
556_P	594_Q	0.501	0.86
502_P	505_Q	0.501	0.86
170_V	201_T	0.501	0.86
444_P	448_A	0.500	0.85
123_Y	126_V	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2e7zA	1	0.9805	100	0.173	Contact Map
2vpzA	1	0.9745	100	0.186	Contact Map
1h0hA	1	0.9895	100	0.187	Contact Map
1kqfA	3	0.991	100	0.189	Contact Map
2iv2X	1	0.9325	100	0.19	Contact Map
2napA	1	0.964	100	0.198	Contact Map
3ml1A	1	0.9655	100	0.205	Contact Map
2ivfA	1	0.982	100	0.206	Contact Map
1ti6A	3	0.991	100	0.218	Contact Map
1q16A	2	0.994	100	0.227	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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