YYAL - BACSU - GREMLIN Contacts

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YYAL - Uncharacterized protein YyaL

UniProt:	P37512	Sequences: MPNKSKPNRLINEKSPYLLQHAHNPVDWFPWGEEAFEKAKRENKPVLVSIGYSTCHWCHVMAHESFEDEEIARLLNERFVAIKVDREERPDVDSVYMRICQLMTGQGGWPLNVFITPDQKPFYAGTYFPKTSKFNRPGFVDVLEHLSETFANDREHVEDIAENAAKHLQTKTAAKTGEGLSESAIHRTFQQLASGFDTIYGGFGQAPKFPMPHMLMYLLRYDHNTGQENALYNVTKTLDSMANGGIYDHIGYGFARYSTDDEWLVPHFEKMLYDNALLLTAYTEAYQVTQNSRYKEICEQIITFIQREMTHEDGSFFSALDADTEGEEGKYYVWSKEEILKTLGDDLGTLYCQVYDITEEGNFEGKNIPNLIHTKREQIKEDAGLTEKELSLKLEDARQQLLKTREERTYPHVDDKVLTSWNALMIAGLAKAAKVYQEPKYLSLAKDAITFIENKLIIDGRVMVRYRDGEVKNKGFIDDYAFLLWAYLDLYEASFDLSYLQKAKKLTDDMISLFWDEEHGGFYFTGHDAEALIVREKEVYDGAVPSGNSVAAVQLLRLGQVTGDLSLIEKAETMFSVFKPDIEAYPSGHAFFMQSVLRHLMPKKEIVIFGSADDPARKQIIAELQKAFKPNDSILVAEQPEQCKDIAPFAADYRIIDGKTTVYICENFACQQPTTNIEEAIHTLISSRD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	689 (658)
Sequences:	1692 (1273)
Seq/√Len:	49.6

BACSU - YYAL
HALSA - Q9HQ68 Q9HNX2
SULSO - Q97WL2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
433_A	442_L	5.099	1.00
423_A	486_A	5.067	1.00
43_N	154_R	4.937	1.00
306_Q	444_L	4.495	1.00
247_Y	300_Q	4.483	1.00
305_I	425_M	4.206	1.00
38_K	42_E	3.955	1.00
75_L	81_A	3.857	1.00
153_D	156_H	3.675	1.00
299_E	438_E	3.669	1.00
125_G	128_F	3.636	1.00
279_L	302_I	3.602	1.00
510_M	551_A	3.529	1.00
513_L	527_H	3.524	1.00
304_F	320_L	3.455	1.00
132_S	141_D	3.326	1.00
71_I	140_V	3.310	1.00
148_E	152_N	3.157	1.00
427_A	489_D	3.136	1.00
426_I	448_A	3.082	1.00
68_D	130_K	3.063	1.00
453_E	502_K	3.037	1.00
446_K	496_D	2.982	1.00
7_P	23_H	2.945	1.00
48_V	115_I	2.909	1.00
196_F	236_K	2.906	1.00
37_E	41_R	2.882	1.00
73_R	77_E	2.843	1.00
484_L	554_Q	2.814	1.00
295_K	299_E	2.789	1.00
415_D	467_R	2.756	1.00
36_F	92_V	2.742	1.00
511_I	522_F	2.724	1.00
477_I	547_G	2.693	1.00
100_C	124_A	2.657	1.00
331_Y	410_Y	2.625	1.00
330_K	409_T	2.591	1.00
302_I	429_L	2.583	1.00
45_P	122_F	2.549	1.00
47_L	112_N	2.532	1.00
71_I	130_K	2.493	1.00
53_S	319_A	2.435	1.00
606_I	664_I	2.430	1.00
308_E	320_L	2.425	1.00
9_R	27_D	2.371	1.00
13_E	30_P	2.364	1.00
511_I	570_K	2.320	1.00
69_E	73_R	2.311	1.00
325_E	330_K	2.310	1.00
326_G	330_K	2.295	1.00
283_T	436_Y	2.281	1.00
235_T	291_N	2.249	1.00
38_K	80_V	2.249	1.00
36_F	46_V	2.248	1.00
310_T	447_D	2.232	1.00
507_T	554_Q	2.226	1.00
71_I	138_G	2.219	1.00
50_I	111_L	2.195	1.00
365_G	368_I	2.188	1.00
46_V	115_I	2.182	1.00
239_D	294_Y	2.174	1.00
662_V	680_A	2.150	1.00
120_K	162_E	2.119	1.00
32_G	35_A	2.117	1.00
54_T	319_A	2.109	1.00
324_T	331_Y	2.098	1.00
365_G	369_P	2.084	1.00
342_T	404_T	2.084	1.00
74_L	140_V	2.071	1.00
222_D	231_L	2.059	1.00
492_E	557_R	2.029	1.00
302_I	432_A	2.018	1.00
344_G	347_L	2.018	1.00
29_F	38_K	2.009	1.00
295_K	436_Y	1.996	1.00
242_A	282_Y	1.996	1.00
449_I	499_Y	1.995	1.00
11_I	23_H	1.993	1.00
453_E	487_Y	1.977	0.99
239_D	291_N	1.976	0.99
366_K	369_P	1.974	0.99
236_K	240_S	1.967	0.99
196_F	233_N	1.963	0.99
154_R	158_E	1.960	0.99
9_R	29_F	1.932	0.99
342_T	400_Q	1.929	0.99
482_F	550_V	1.918	0.99
420_S	464_V	1.915	0.99
282_Y	297_I	1.899	0.99
112_N	139_F	1.884	0.99
278_L	282_Y	1.884	0.99
311_H	317_F	1.869	0.99
189_F	230_A	1.866	0.99
242_A	297_I	1.866	0.99
254_F	278_L	1.862	0.99
251_G	307_R	1.855	0.99
238_L	285_A	1.854	0.99
549_S	591_F	1.842	0.99
396_D	400_Q	1.794	0.99
304_F	309_M	1.787	0.99
137_P	142_V	1.772	0.99
450_T	498_S	1.769	0.99
239_D	293_R	1.768	0.99
215_L	234_V	1.758	0.99
357_I	369_P	1.748	0.99
216_M	284_E	1.748	0.99
516_D	537_K	1.739	0.99
419_T	483_L	1.737	0.99
29_F	32_G	1.735	0.99
327_E	330_K	1.734	0.99
254_F	282_Y	1.727	0.99
147_S	151_A	1.711	0.98
33_E	37_E	1.710	0.98
674_T	683_T	1.702	0.98
676_N	679_E	1.677	0.98
461_R	528_D	1.676	0.98
315_S	451_F	1.658	0.98
366_K	370_N	1.657	0.98
46_V	82_I	1.648	0.98
74_L	144_E	1.643	0.98
350_L	393_K	1.642	0.98
325_E	409_T	1.616	0.98
68_D	71_I	1.615	0.98
276_A	428_G	1.594	0.98
443_S	446_K	1.585	0.97
521_G	537_K	1.581	0.97
429_L	444_L	1.579	0.97
9_R	34_E	1.577	0.97
283_T	428_G	1.575	0.97
449_I	487_Y	1.571	0.97
220_R	284_E	1.569	0.97
193_A	233_N	1.569	0.97
324_T	410_Y	1.567	0.97
523_Y	535_R	1.562	0.97
427_A	485_W	1.545	0.97
656_I	661_T	1.538	0.97
449_I	490_L	1.537	0.97
74_L	78_R	1.529	0.97
23_H	62_A	1.523	0.97
355_Y	394_L	1.515	0.97
130_K	140_V	1.506	0.97
280_T	431_K	1.504	0.97
351_Y	355_Y	1.500	0.96
344_G	348_G	1.481	0.96
525_T	535_R	1.472	0.96
604_K	666_E	1.465	0.96
53_S	412_H	1.463	0.96
339_I	357_I	1.460	0.96
442_L	493_A	1.457	0.96
548_N	578_F	1.455	0.96
354_V	394_L	1.453	0.96
508_D	567_L	1.451	0.96
95_V	533_I	1.450	0.96
621_I	625_Q	1.441	0.96
296_E	300_Q	1.440	0.96
188_T	593_M	1.429	0.95
559_G	562_T	1.428	0.95
320_L	410_Y	1.427	0.95
513_L	526_G	1.420	0.95
438_E	441_Y	1.418	0.95
114_F	139_F	1.416	0.95
63_H	67_E	1.412	0.95
484_L	507_T	1.411	0.95
231_L	289_T	1.409	0.95
606_I	632_D	1.392	0.95
446_K	499_Y	1.388	0.95
450_T	454_N	1.386	0.95
284_E	431_K	1.386	0.95
523_Y	537_K	1.385	0.94
661_T	675_T	1.384	0.94
116_T	120_K	1.382	0.94
402_L	406_E	1.374	0.94
564_D	567_L	1.364	0.94
516_D	523_Y	1.363	0.94
357_I	361_G	1.358	0.94
559_G	568_I	1.347	0.94
509_D	513_L	1.334	0.93
515_W	570_K	1.330	0.93
339_I	352_C	1.326	0.93
78_R	147_S	1.325	0.93
461_R	513_L	1.315	0.93
221_Y	230_A	1.302	0.92
306_Q	440_K	1.302	0.92
54_T	412_H	1.299	0.92
572_E	599_H	1.297	0.92
305_I	309_M	1.297	0.92
410_Y	413_V	1.295	0.92
491_Y	495_F	1.294	0.92
145_H	149_T	1.275	0.92
552_A	595_S	1.274	0.92
247_Y	296_E	1.268	0.91
326_G	409_T	1.268	0.91
255_A	275_N	1.267	0.91
19_L	467_R	1.266	0.91
47_L	75_L	1.266	0.91
674_T	680_A	1.262	0.91
222_D	288_V	1.259	0.91
279_L	432_A	1.259	0.91
200_Y	261_D	1.256	0.91
189_F	221_Y	1.254	0.91
463_M	471_V	1.253	0.91
451_F	455_K	1.251	0.91
11_I	22_A	1.250	0.91
430_A	433_A	1.246	0.91
334_W	404_T	1.240	0.90
336_K	352_C	1.238	0.90
203_F	215_L	1.236	0.90
279_L	428_G	1.234	0.90
351_Y	397_A	1.233	0.90
298_C	432_A	1.232	0.90
320_L	413_V	1.225	0.90
307_R	402_L	1.221	0.90
24_N	62_A	1.217	0.90
87_E	416_K	1.216	0.90
79_F	114_F	1.216	0.90
114_F	123_Y	1.214	0.90
48_V	112_N	1.213	0.89
502_K	505_K	1.210	0.89
367_N	370_N	1.209	0.89
316_F	448_A	1.206	0.89
302_I	444_L	1.199	0.89
97_M	107_G	1.195	0.89
300_Q	398_R	1.192	0.89
406_E	410_Y	1.190	0.89
303_T	440_K	1.190	0.89
340_L	348_G	1.187	0.88
213_H	277_L	1.185	0.88
486_A	490_L	1.184	0.88
347_L	397_A	1.184	0.88
504_K	567_L	1.182	0.88
114_F	146_L	1.180	0.88
305_I	310_T	1.175	0.88
103_M	164_A	1.168	0.88
347_L	400_Q	1.165	0.87
340_L	345_D	1.159	0.87
339_I	351_Y	1.156	0.87
149_T	153_D	1.155	0.87
24_N	67_E	1.154	0.87
419_T	423_A	1.146	0.87
11_I	27_D	1.144	0.87
251_G	402_L	1.143	0.86
315_S	417_V	1.142	0.86
507_T	522_F	1.139	0.86
310_T	444_L	1.137	0.86
331_Y	402_L	1.136	0.86
302_I	441_Y	1.132	0.86
283_T	435_V	1.131	0.86
552_A	574_M	1.130	0.86
120_K	161_A	1.126	0.86
7_P	11_I	1.121	0.85
38_K	41_R	1.121	0.85
247_Y	301_I	1.120	0.85
299_E	441_Y	1.119	0.85
507_T	558_L	1.118	0.85
679_E	682_H	1.104	0.84
246_I	258_S	1.103	0.84
140_V	144_E	1.102	0.84
485_W	489_D	1.102	0.84
320_L	332_Y	1.101	0.84
504_K	564_D	1.100	0.84
219_L	234_V	1.100	0.84
553_V	598_R	1.099	0.84
247_Y	297_I	1.096	0.84
241_M	282_Y	1.095	0.84
399_Q	403_K	1.092	0.84
100_C	113_V	1.090	0.84
508_D	564_D	1.090	0.84
575_F	599_H	1.087	0.84
224_N	597_L	1.084	0.83
49_S	52_Y	1.077	0.83
350_L	390_L	1.075	0.83
424_L	482_F	1.074	0.83
340_L	352_C	1.070	0.83
442_L	446_K	1.070	0.83
456_L	466_Y	1.068	0.82
264_L	368_I	1.068	0.82
434_K	625_Q	1.067	0.82
299_E	436_Y	1.065	0.82
112_N	115_I	1.064	0.82
347_L	393_K	1.063	0.82
21_H	24_N	1.061	0.82
254_F	297_I	1.061	0.82
21_H	52_Y	1.060	0.82
312_E	317_F	1.059	0.82
38_K	44_K	1.057	0.82
457_I	502_K	1.056	0.82
279_L	429_L	1.055	0.82
620_I	662_V	1.053	0.82
283_T	432_A	1.053	0.82
23_H	63_H	1.052	0.81
498_S	502_K	1.050	0.81
540_Y	588_G	1.047	0.81
539_V	578_F	1.046	0.81
115_I	119_Q	1.043	0.81
365_G	370_N	1.040	0.81
674_T	679_E	1.036	0.80
279_L	283_T	1.035	0.80
29_F	34_E	1.034	0.80
526_G	529_A	1.032	0.80
284_E	287_Q	1.030	0.80
537_K	548_N	1.028	0.80
453_E	498_S	1.022	0.80
655_I	661_T	1.019	0.79
27_D	30_P	1.015	0.79
235_T	294_Y	1.013	0.79
27_D	38_K	1.010	0.79
92_V	97_M	1.005	0.78
148_E	153_D	1.004	0.78
453_E	457_I	1.004	0.78
70_E	140_V	1.003	0.78
193_A	229_N	1.003	0.78
250_I	398_R	1.001	0.78
298_C	436_Y	0.999	0.78
16_P	19_L	0.998	0.78
483_L	487_Y	0.997	0.78
29_F	35_A	0.997	0.78
243_N	293_R	0.990	0.77
629_K	632_D	0.986	0.77
14_K	465_R	0.981	0.77
607_V	650_A	0.980	0.77
488_L	567_L	0.978	0.76
336_K	348_G	0.977	0.76
98_R	102_L	0.975	0.76
249_H	402_L	0.974	0.76
37_E	40_K	0.973	0.76
368_I	371_L	0.967	0.76
449_I	486_A	0.966	0.76
310_T	425_M	0.964	0.75
62_A	112_N	0.963	0.75
100_C	104_T	0.961	0.75
423_A	483_L	0.961	0.75
132_S	138_G	0.961	0.75
450_T	499_Y	0.960	0.75
476_F	524_F	0.959	0.75
217_Y	221_Y	0.958	0.75
207_P	261_D	0.956	0.75
464_V	476_F	0.954	0.75
446_K	450_T	0.953	0.75
484_L	510_M	0.953	0.75
317_F	417_V	0.952	0.75
450_T	453_E	0.949	0.74
395_E	399_Q	0.948	0.74
200_Y	262_E	0.948	0.74
431_K	489_D	0.947	0.74
404_T	407_E	0.945	0.74
551_A	554_Q	0.945	0.74
356_D	370_N	0.945	0.74
666_E	671_Q	0.943	0.74
279_L	301_I	0.942	0.74
291_N	294_Y	0.942	0.74
159_D	163_N	0.940	0.74
442_L	494_S	0.938	0.73
386_T	389_E	0.937	0.73
672_Q	679_E	0.929	0.73
395_E	398_R	0.929	0.73
120_K	165_A	0.926	0.72
287_Q	435_V	0.925	0.72
473_N	476_F	0.924	0.72
439_P	443_S	0.923	0.72
522_F	574_M	0.923	0.72
324_T	330_K	0.922	0.72
222_D	225_T	0.921	0.72
513_L	528_D	0.919	0.72
20_Q	24_N	0.917	0.72
624_L	680_A	0.915	0.72
451_F	466_Y	0.912	0.71
639_Q	655_I	0.909	0.71
364_E	368_I	0.904	0.71
197_D	208_K	0.903	0.71
246_I	301_I	0.900	0.70
556_L	599_H	0.898	0.70
229_N	232_Y	0.897	0.70
17_Y	21_H	0.895	0.70
241_M	254_F	0.895	0.70
250_I	369_P	0.894	0.70
339_I	348_G	0.892	0.70
14_K	470_E	0.892	0.70
318_S	421_W	0.892	0.70
48_V	96_Y	0.892	0.70
419_T	456_L	0.892	0.70
264_L	363_F	0.891	0.70
21_H	49_S	0.889	0.69
474_K	526_G	0.887	0.69
100_C	111_L	0.887	0.69
19_L	415_D	0.884	0.69
620_I	624_L	0.883	0.69
97_M	102_L	0.883	0.69
52_Y	416_K	0.882	0.69
508_D	566_S	0.882	0.69
568_I	572_E	0.876	0.68
330_K	333_V	0.874	0.68
647_A	650_A	0.873	0.68
662_V	677_I	0.871	0.68
306_Q	429_L	0.871	0.68
222_D	226_G	0.870	0.68
99_I	164_A	0.870	0.68
507_T	510_M	0.870	0.68
326_G	363_F	0.869	0.68
478_D	524_F	0.869	0.68
504_K	508_D	0.869	0.68
279_L	441_Y	0.868	0.67
133_K	136_R	0.868	0.67
217_Y	590_A	0.868	0.67
280_T	485_W	0.867	0.67
99_I	124_A	0.866	0.67
57_W	60_V	0.865	0.67
423_A	427_A	0.865	0.67
21_H	416_K	0.862	0.67
516_D	519_H	0.860	0.67
560_Q	568_I	0.860	0.67
664_I	674_T	0.860	0.67
354_V	372_I	0.858	0.67
507_T	511_I	0.858	0.67
228_E	232_Y	0.857	0.66
7_P	27_D	0.856	0.66
113_V	124_A	0.856	0.66
89_R	476_F	0.856	0.66
215_L	281_A	0.854	0.66
283_T	302_I	0.852	0.66
129_P	138_G	0.852	0.66
297_I	300_Q	0.852	0.66
478_D	547_G	0.850	0.66
336_K	340_L	0.847	0.66
78_R	143_L	0.847	0.66
620_I	660_T	0.844	0.65
443_S	447_D	0.842	0.65
75_L	139_F	0.842	0.65
216_M	628_F	0.841	0.65
68_D	140_V	0.841	0.65
30_P	35_A	0.840	0.65
56_H	60_V	0.838	0.65
609_F	655_I	0.836	0.65
13_E	472_K	0.836	0.65
306_Q	310_T	0.833	0.64
623_E	681_I	0.822	0.63
393_K	397_A	0.822	0.63
442_L	490_L	0.820	0.63
9_R	35_A	0.820	0.63
433_A	438_E	0.820	0.63
46_V	119_Q	0.819	0.63
125_G	275_N	0.817	0.63
21_H	271_M	0.817	0.63
358_T	361_G	0.817	0.63
52_Y	87_E	0.812	0.62
286_Y	298_C	0.812	0.62
484_L	551_A	0.811	0.62
238_L	281_A	0.811	0.62
311_H	417_V	0.810	0.62
656_I	675_T	0.810	0.62
477_I	510_M	0.808	0.62
457_I	460_G	0.808	0.62
103_M	124_A	0.806	0.62
99_I	103_M	0.805	0.62
146_L	157_V	0.805	0.62
251_G	308_E	0.804	0.62
504_K	562_T	0.804	0.62
310_T	448_A	0.803	0.61
241_M	249_H	0.803	0.61
160_I	164_A	0.797	0.61
334_W	401_L	0.795	0.61
249_H	351_Y	0.794	0.61
398_R	402_L	0.794	0.61
189_F	193_A	0.793	0.60
242_A	254_F	0.792	0.60
196_F	237_T	0.792	0.60
623_E	626_K	0.791	0.60
364_E	369_P	0.790	0.60
320_L	331_Y	0.790	0.60
21_H	87_E	0.789	0.60
522_F	570_K	0.787	0.60
56_H	323_D	0.787	0.60
258_S	262_E	0.785	0.60
671_Q	683_T	0.785	0.60
279_L	298_C	0.783	0.59
68_D	124_A	0.782	0.59
234_V	281_A	0.782	0.59
97_M	105_G	0.780	0.59
426_I	490_L	0.779	0.59
355_Y	398_R	0.778	0.59
148_E	679_E	0.776	0.59
562_T	565_L	0.775	0.59
336_K	359_E	0.773	0.58
565_L	569_E	0.772	0.58
340_L	349_T	0.772	0.58
510_M	513_L	0.772	0.58
496_D	499_Y	0.771	0.58
656_I	659_K	0.769	0.58
309_M	409_T	0.766	0.58
99_I	119_Q	0.765	0.58
331_Y	406_E	0.764	0.58
299_E	440_K	0.764	0.58
485_W	553_V	0.764	0.58
532_L	536_E	0.761	0.57
279_L	425_M	0.761	0.57
125_G	139_F	0.761	0.57
550_V	554_Q	0.758	0.57
561_V	635_L	0.758	0.57
63_H	323_D	0.757	0.57
49_S	57_W	0.754	0.57
413_V	467_R	0.754	0.57
14_K	19_L	0.754	0.57
386_T	390_L	0.750	0.56
52_Y	56_H	0.750	0.56
316_F	425_M	0.748	0.56
301_I	308_E	0.747	0.56
658_G	663_Y	0.747	0.56
285_A	294_Y	0.747	0.56
206_A	255_A	0.746	0.56
128_F	139_F	0.746	0.56
24_N	52_Y	0.746	0.56
461_R	526_G	0.746	0.56
657_D	661_T	0.744	0.56
36_F	54_T	0.743	0.55
665_C	670_C	0.743	0.55
430_A	486_A	0.741	0.55
432_A	436_Y	0.740	0.55
249_H	370_N	0.740	0.55
231_L	235_T	0.740	0.55
606_I	662_V	0.739	0.55
296_E	391_S	0.738	0.55
489_D	557_R	0.737	0.55
677_I	681_I	0.735	0.55
311_H	466_Y	0.734	0.55
49_S	83_K	0.733	0.54
457_I	462_V	0.733	0.54
250_I	351_Y	0.732	0.54
433_A	493_A	0.731	0.54
138_G	141_D	0.731	0.54
29_F	42_E	0.731	0.54
337_E	341_K	0.730	0.54
364_E	367_N	0.729	0.54
402_L	410_Y	0.728	0.54
358_T	367_N	0.726	0.54
24_N	49_S	0.726	0.54
620_I	677_I	0.726	0.54
32_G	36_F	0.726	0.54
182_E	186_H	0.725	0.54
453_E	483_L	0.725	0.54
581_D	589_H	0.725	0.54
624_L	662_V	0.724	0.54
265_V	368_I	0.723	0.53
259_T	363_F	0.723	0.53
36_F	81_A	0.721	0.53
487_Y	502_K	0.719	0.53
608_I	662_V	0.718	0.53
515_W	573_T	0.716	0.53
656_I	663_Y	0.715	0.53
605_E	667_N	0.714	0.53
462_V	475_G	0.712	0.52
346_D	393_K	0.711	0.52
433_A	436_Y	0.709	0.52
277_L	428_G	0.708	0.52
316_F	444_L	0.708	0.52
647_A	651_A	0.707	0.52
311_H	315_S	0.706	0.52
578_F	592_F	0.705	0.52
307_R	331_Y	0.705	0.52
235_T	239_D	0.703	0.51
449_I	506_L	0.703	0.51
277_L	281_A	0.703	0.51
486_A	506_L	0.703	0.51
419_T	487_Y	0.701	0.51
509_D	512_S	0.701	0.51
189_F	217_Y	0.700	0.51
149_T	157_V	0.699	0.51
418_L	465_R	0.698	0.51
27_D	34_E	0.698	0.51
449_I	483_L	0.698	0.51
350_L	397_A	0.698	0.51
49_S	60_V	0.696	0.51
16_P	415_D	0.694	0.50
156_H	160_I	0.694	0.50
507_T	551_A	0.694	0.50
150_F	158_E	0.694	0.50
141_D	145_H	0.691	0.50
623_E	680_A	0.690	0.50
324_T	409_T	0.690	0.50
216_M	281_A	0.689	0.50
239_D	243_N	0.689	0.50
211_M	214_M	0.689	0.50
221_Y	225_T	0.685	0.50
149_T	156_H	0.685	0.50
275_N	420_S	0.684	0.49
188_T	551_A	0.684	0.49
339_I	355_Y	0.679	0.49
308_E	413_V	0.679	0.49
475_G	514_F	0.679	0.49
56_H	59_H	0.678	0.49
219_L	288_V	0.677	0.49
432_A	441_Y	0.677	0.49
184_A	579_K	0.676	0.49
202_G	208_K	0.675	0.49
43_N	151_A	0.675	0.49
113_V	128_F	0.675	0.49
123_Y	145_H	0.674	0.48
221_Y	597_L	0.674	0.48
433_A	494_S	0.674	0.48
255_A	473_N	0.673	0.48
69_E	77_E	0.673	0.48
475_G	482_F	0.672	0.48
465_R	470_E	0.671	0.48
26_V	30_P	0.671	0.48
70_E	73_R	0.671	0.48
622_A	626_K	0.670	0.48
283_T	298_C	0.670	0.48
623_E	677_I	0.670	0.48
251_G	324_T	0.669	0.48
104_T	124_A	0.669	0.48
664_I	680_A	0.669	0.48
501_Q	505_K	0.669	0.48
344_G	400_Q	0.666	0.48
106_Q	136_R	0.664	0.47
77_E	147_S	0.663	0.47
420_S	478_D	0.663	0.47
426_I	483_L	0.662	0.47
79_F	147_S	0.662	0.47
612_A	638_E	0.662	0.47
302_I	428_G	0.661	0.47
114_F	128_F	0.660	0.47
197_D	202_G	0.660	0.47
77_E	345_D	0.659	0.47
356_D	373_H	0.659	0.47
510_M	554_Q	0.658	0.47
207_P	258_S	0.657	0.47
279_L	305_I	0.657	0.47
242_A	252_Y	0.656	0.47
10_L	18_L	0.655	0.47
43_N	117_P	0.655	0.47
427_A	486_A	0.654	0.46
649_F	652_D	0.654	0.46
357_I	367_N	0.652	0.46
24_N	273_Y	0.652	0.46
130_K	138_G	0.651	0.46
298_C	441_Y	0.650	0.46
280_T	428_G	0.650	0.46
96_Y	125_G	0.649	0.46
553_V	591_F	0.649	0.46
52_Y	57_W	0.649	0.46
622_A	625_Q	0.648	0.46
465_R	472_K	0.647	0.46
553_V	595_S	0.647	0.46
24_N	53_S	0.646	0.46
569_E	573_T	0.646	0.46
20_Q	67_E	0.643	0.45
52_Y	66_F	0.643	0.45
132_S	137_P	0.642	0.45
231_L	288_V	0.642	0.45
132_S	135_N	0.641	0.45
487_Y	499_Y	0.640	0.45
235_T	285_A	0.640	0.45
132_S	140_V	0.640	0.45
48_V	111_L	0.638	0.45
21_H	53_S	0.638	0.45
120_K	158_E	0.638	0.45
20_Q	53_S	0.637	0.45
78_R	81_A	0.637	0.45
457_I	509_D	0.636	0.45
52_Y	55_C	0.635	0.44
168_L	534_V	0.634	0.44
452_I	462_V	0.634	0.44
189_F	233_N	0.633	0.44
607_V	649_F	0.632	0.44
275_N	364_E	0.632	0.44
25_P	49_S	0.631	0.44
602_P	666_E	0.631	0.44
192_L	214_M	0.631	0.44
272_L	425_M	0.630	0.44
350_L	394_L	0.629	0.44
92_V	115_I	0.629	0.44
283_T	287_Q	0.628	0.44
390_L	397_A	0.627	0.44
8_N	18_L	0.627	0.44
75_L	465_R	0.627	0.44
457_I	505_K	0.627	0.44
287_Q	628_F	0.626	0.44
497_L	501_Q	0.626	0.44
267_H	271_M	0.626	0.44
259_T	546_S	0.625	0.43
53_S	450_T	0.625	0.43
74_L	143_L	0.624	0.43
335_S	338_E	0.624	0.43
347_L	396_D	0.624	0.43
17_Y	271_M	0.623	0.43
189_F	227_Q	0.623	0.43
18_L	21_H	0.623	0.43
419_T	463_M	0.622	0.43
100_C	332_Y	0.621	0.43
49_S	271_M	0.621	0.43
252_Y	303_T	0.620	0.43
60_V	83_K	0.619	0.43
162_E	166_K	0.619	0.43
133_K	137_P	0.619	0.43
596_V	600_L	0.618	0.43
548_N	552_A	0.618	0.43
18_L	49_S	0.618	0.43
201_G	240_S	0.617	0.43
10_L	60_V	0.617	0.43
415_D	469_G	0.617	0.43
51_G	56_H	0.617	0.43
29_F	36_F	0.616	0.43
9_R	30_P	0.615	0.42
250_I	357_I	0.615	0.42
455_K	466_Y	0.615	0.42
662_V	674_T	0.614	0.42
451_F	456_L	0.614	0.42
566_S	570_K	0.613	0.42
193_A	227_Q	0.613	0.42
264_L	371_L	0.613	0.42
49_S	87_E	0.613	0.42
30_P	33_E	0.613	0.42
223_H	630_P	0.613	0.42
16_P	24_N	0.612	0.42
83_K	273_Y	0.611	0.42
492_E	561_V	0.611	0.42
161_A	165_A	0.611	0.42
430_A	490_L	0.611	0.42
95_V	532_L	0.610	0.42
55_C	60_V	0.610	0.42
93_D	267_H	0.609	0.42
51_G	58_C	0.609	0.42
475_G	483_L	0.609	0.42
135_N	138_G	0.609	0.42
658_G	664_I	0.608	0.42
89_R	95_V	0.607	0.42
215_L	237_T	0.606	0.42
36_F	119_Q	0.606	0.42
306_Q	316_F	0.606	0.42
426_I	449_I	0.606	0.42
163_N	166_K	0.606	0.42
558_L	567_L	0.606	0.42
273_Y	421_W	0.606	0.42
44_K	80_V	0.605	0.41
131_T	140_V	0.605	0.41
426_I	452_I	0.605	0.41
257_Y	267_H	0.604	0.41
512_S	566_S	0.604	0.41
521_G	578_F	0.604	0.41
21_H	54_T	0.604	0.41
101_Q	104_T	0.603	0.41
155_E	158_E	0.602	0.41
55_C	58_C	0.601	0.41
244_G	258_S	0.600	0.41
301_I	320_L	0.600	0.41
275_N	370_N	0.600	0.41
640_P	645_D	0.599	0.41
426_I	486_A	0.599	0.41
611_S	660_T	0.599	0.41
265_V	364_E	0.599	0.41
100_C	125_G	0.598	0.41
663_Y	673_P	0.598	0.41
458_I	463_M	0.598	0.41
145_H	148_E	0.598	0.41
107_G	125_G	0.596	0.41
303_T	306_Q	0.595	0.40
658_G	661_T	0.595	0.40
303_T	307_R	0.594	0.40
131_T	141_D	0.594	0.40
106_Q	428_G	0.594	0.40
140_V	259_T	0.594	0.40
48_V	543_A	0.594	0.40
624_L	629_K	0.592	0.40
26_V	81_A	0.592	0.40
303_T	441_Y	0.592	0.40
203_F	233_N	0.592	0.40
632_D	664_I	0.592	0.40
105_G	203_F	0.591	0.40
358_T	362_N	0.590	0.40
264_L	358_T	0.589	0.40
286_Y	289_T	0.588	0.40
205_Q	261_D	0.588	0.40
358_T	363_F	0.588	0.40
62_A	66_F	0.587	0.40
309_M	319_A	0.587	0.40
327_E	365_G	0.585	0.40
454_N	523_Y	0.585	0.40
43_N	158_E	0.584	0.39
452_I	483_L	0.584	0.39
63_H	102_L	0.583	0.39
55_C	93_D	0.582	0.39
235_T	289_T	0.581	0.39
52_Y	273_Y	0.581	0.39
252_Y	398_R	0.581	0.39
63_H	258_S	0.580	0.39
35_A	38_K	0.576	0.39
282_Y	285_A	0.573	0.38
556_L	595_S	0.573	0.38
401_L	405_R	0.572	0.38
35_A	80_V	0.572	0.38
375_K	390_L	0.571	0.38
24_N	416_K	0.570	0.38
570_K	573_T	0.570	0.38
97_M	101_Q	0.570	0.38
17_Y	49_S	0.569	0.38
48_V	84_V	0.569	0.38
87_E	97_M	0.567	0.38
36_F	75_L	0.566	0.38
107_G	126_T	0.566	0.38
624_L	634_I	0.565	0.38
388_K	391_S	0.564	0.37
336_K	363_F	0.563	0.37
259_T	342_T	0.563	0.37
485_W	554_Q	0.563	0.37
43_N	450_T	0.562	0.37
308_E	410_Y	0.562	0.37
546_S	549_S	0.561	0.37
81_A	240_S	0.561	0.37
54_T	275_N	0.561	0.37
580_P	584_A	0.560	0.37
112_N	543_A	0.560	0.37
611_S	638_E	0.559	0.37
21_H	273_Y	0.558	0.37
55_C	267_H	0.558	0.37
542_G	588_G	0.558	0.37
9_R	32_G	0.558	0.37
10_L	49_S	0.557	0.37
346_D	678_E	0.556	0.37
52_Y	97_M	0.555	0.37
334_W	411_P	0.555	0.37
97_M	542_G	0.555	0.37
16_P	21_H	0.554	0.37
287_Q	630_P	0.554	0.37
242_A	249_H	0.552	0.36
27_D	35_A	0.552	0.36
355_Y	667_N	0.551	0.36
273_Y	416_K	0.551	0.36
298_C	301_I	0.550	0.36
524_F	536_E	0.550	0.36
356_D	371_L	0.550	0.36
423_A	487_Y	0.550	0.36
677_I	680_A	0.550	0.36
465_R	473_N	0.549	0.36
492_E	632_D	0.549	0.36
49_S	53_S	0.549	0.36
49_S	55_C	0.548	0.36
363_F	368_I	0.548	0.36
264_L	370_N	0.548	0.36
118_D	657_D	0.547	0.36
255_A	332_Y	0.547	0.36
7_P	12_N	0.546	0.36
449_I	502_K	0.546	0.36
264_L	369_P	0.546	0.36
242_A	293_R	0.546	0.36
585_Y	588_G	0.545	0.36
79_F	143_L	0.545	0.36
13_E	402_L	0.544	0.36
330_K	363_F	0.544	0.36
276_A	425_M	0.544	0.36
333_V	357_I	0.544	0.36
41_R	80_V	0.543	0.35
304_F	308_E	0.543	0.35
350_L	354_V	0.543	0.35
93_D	256_R	0.543	0.35
228_E	235_T	0.543	0.35
464_V	544_V	0.542	0.35
431_K	434_K	0.541	0.35
624_L	681_I	0.540	0.35
286_Y	295_K	0.540	0.35
97_M	211_M	0.539	0.35
17_Y	24_N	0.539	0.35
119_Q	464_V	0.539	0.35
610_G	660_T	0.539	0.35
230_A	234_V	0.539	0.35
123_Y	593_M	0.538	0.35
216_M	591_F	0.538	0.35
430_A	434_K	0.538	0.35
578_F	581_D	0.538	0.35
50_I	178_E	0.537	0.35
575_F	600_L	0.537	0.35
357_I	370_N	0.537	0.35
20_Q	52_Y	0.537	0.35
582_I	593_M	0.537	0.35
488_L	667_N	0.537	0.35
279_L	303_T	0.537	0.35
122_F	316_F	0.536	0.35
430_A	489_D	0.536	0.35
61_M	83_K	0.535	0.35
201_G	208_K	0.535	0.35
669_A	672_Q	0.535	0.35
236_K	293_R	0.534	0.35
45_P	114_F	0.533	0.35
160_I	585_Y	0.533	0.35
62_A	331_Y	0.533	0.35
15_S	18_L	0.532	0.34
607_V	637_A	0.532	0.34
55_C	59_H	0.532	0.34
105_G	276_A	0.531	0.34
330_K	491_Y	0.531	0.34
507_T	567_L	0.531	0.34
304_F	500_L	0.530	0.34
18_L	25_P	0.530	0.34
190_Q	193_A	0.530	0.34
52_Y	60_V	0.529	0.34
196_F	203_F	0.528	0.34
485_W	550_V	0.528	0.34
67_E	112_N	0.528	0.34
82_I	407_E	0.528	0.34
466_Y	471_V	0.527	0.34
667_N	671_Q	0.526	0.34
93_D	209_F	0.526	0.34
331_Y	409_T	0.526	0.34
522_F	548_N	0.525	0.34
327_E	409_T	0.525	0.34
446_K	494_S	0.525	0.34
546_S	552_A	0.524	0.34
11_I	29_F	0.524	0.34
14_K	301_I	0.524	0.34
31_W	57_W	0.523	0.34
490_L	493_A	0.523	0.34
619_Q	678_E	0.523	0.34
137_P	141_D	0.522	0.34
24_N	271_M	0.522	0.34
265_V	333_V	0.522	0.34
178_E	622_A	0.521	0.33
185_I	597_L	0.520	0.33
50_I	511_I	0.520	0.33
17_Y	25_P	0.519	0.33
420_S	482_F	0.519	0.33
611_S	677_I	0.519	0.33
389_E	512_S	0.518	0.33
115_I	139_F	0.518	0.33
325_E	331_Y	0.518	0.33
598_R	602_P	0.518	0.33
154_R	157_V	0.518	0.33
468_D	471_V	0.517	0.33
256_R	267_H	0.517	0.33
16_P	467_R	0.516	0.33
556_L	575_F	0.516	0.33
54_T	87_E	0.516	0.33
488_L	558_L	0.515	0.33
84_V	92_V	0.515	0.33
215_L	276_A	0.514	0.33
423_A	426_I	0.513	0.33
529_A	532_L	0.513	0.33
319_A	582_I	0.513	0.33
53_S	416_K	0.513	0.33
178_E	580_P	0.512	0.33
434_K	493_A	0.511	0.33
73_R	78_R	0.511	0.33
29_F	41_R	0.511	0.33
94_S	464_V	0.511	0.33
47_L	139_F	0.510	0.32
114_F	122_F	0.510	0.32
71_I	74_L	0.510	0.32
53_S	57_W	0.510	0.32
79_F	239_D	0.510	0.32
150_F	683_T	0.510	0.32
606_I	610_G	0.510	0.32
122_F	157_V	0.510	0.32
219_L	285_A	0.509	0.32
100_C	213_H	0.509	0.32
491_Y	500_L	0.509	0.32
340_L	344_G	0.509	0.32
52_Y	62_A	0.509	0.32
14_K	468_D	0.509	0.32
33_E	530_E	0.508	0.32
635_L	649_F	0.508	0.32
662_V	675_T	0.507	0.32
19_L	23_H	0.507	0.32
302_I	425_M	0.507	0.32
319_A	591_F	0.507	0.32
87_E	418_L	0.507	0.32
674_T	681_I	0.507	0.32
467_R	522_F	0.506	0.32
304_F	636_V	0.505	0.32
602_P	671_Q	0.505	0.32
40_K	46_V	0.504	0.32
298_C	624_L	0.504	0.32
264_L	330_K	0.504	0.32
32_G	82_I	0.504	0.32
255_A	412_H	0.504	0.32
10_L	31_W	0.503	0.32
271_M	416_K	0.503	0.32
51_G	60_V	0.502	0.32
211_M	590_A	0.502	0.32
258_S	323_D	0.502	0.32
47_L	81_A	0.502	0.32
345_D	349_T	0.502	0.32
252_Y	301_I	0.501	0.32
21_H	25_P	0.501	0.32
299_E	303_T	0.501	0.32
488_L	554_Q	0.501	0.32
427_A	430_A	0.501	0.32
610_G	662_V	0.501	0.32
448_A	451_F	0.500	0.32
166_K	600_L	0.500	0.32
212_P	278_L	0.500	0.32
215_L	250_I	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3vw5A	1	0.5109	100	0.826	Contact Map
3wkgA	1	0.5283	100	0.826	Contact Map
1fp3A	2	0.4964	100	0.827	Contact Map
4c1sA	1	0.4877	100	0.827	Contact Map
2ahfA	1	0.4891	100	0.841	Contact Map
3gt5A	1	0.5341	100	0.844	Contact Map
2gz6A	2	0.5065	100	0.844	Contact Map
4v1sA	1	0.4862	100	0.847	Contact Map
5agdA	1	0.4688	100	0.849	Contact Map
2zzrA	1	0.5385	100	0.849	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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