GREMLIN Database
YYAL - Uncharacterized protein YyaL
UniProt: P37512 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 689 (658)
Sequences: 1692 (1273)
Seq/√Len: 49.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
433_A442_L5.0991.00
423_A486_A5.0671.00
43_N154_R4.9371.00
306_Q444_L4.4951.00
247_Y300_Q4.4831.00
305_I425_M4.2061.00
38_K42_E3.9551.00
75_L81_A3.8571.00
153_D156_H3.6751.00
299_E438_E3.6691.00
125_G128_F3.6361.00
279_L302_I3.6021.00
510_M551_A3.5291.00
513_L527_H3.5241.00
304_F320_L3.4551.00
132_S141_D3.3261.00
71_I140_V3.3101.00
148_E152_N3.1571.00
427_A489_D3.1361.00
426_I448_A3.0821.00
68_D130_K3.0631.00
453_E502_K3.0371.00
446_K496_D2.9821.00
7_P23_H2.9451.00
48_V115_I2.9091.00
196_F236_K2.9061.00
37_E41_R2.8821.00
73_R77_E2.8431.00
484_L554_Q2.8141.00
295_K299_E2.7891.00
415_D467_R2.7561.00
36_F92_V2.7421.00
511_I522_F2.7241.00
477_I547_G2.6931.00
100_C124_A2.6571.00
331_Y410_Y2.6251.00
330_K409_T2.5911.00
302_I429_L2.5831.00
45_P122_F2.5491.00
47_L112_N2.5321.00
71_I130_K2.4931.00
53_S319_A2.4351.00
606_I664_I2.4301.00
308_E320_L2.4251.00
9_R27_D2.3711.00
13_E30_P2.3641.00
511_I570_K2.3201.00
69_E73_R2.3111.00
325_E330_K2.3101.00
326_G330_K2.2951.00
283_T436_Y2.2811.00
235_T291_N2.2491.00
38_K80_V2.2491.00
36_F46_V2.2481.00
310_T447_D2.2321.00
507_T554_Q2.2261.00
71_I138_G2.2191.00
50_I111_L2.1951.00
365_G368_I2.1881.00
46_V115_I2.1821.00
239_D294_Y2.1741.00
662_V680_A2.1501.00
120_K162_E2.1191.00
32_G35_A2.1171.00
54_T319_A2.1091.00
324_T331_Y2.0981.00
365_G369_P2.0841.00
342_T404_T2.0841.00
74_L140_V2.0711.00
222_D231_L2.0591.00
492_E557_R2.0291.00
302_I432_A2.0181.00
344_G347_L2.0181.00
29_F38_K2.0091.00
295_K436_Y1.9961.00
242_A282_Y1.9961.00
449_I499_Y1.9951.00
11_I23_H1.9931.00
453_E487_Y1.9770.99
239_D291_N1.9760.99
366_K369_P1.9740.99
236_K240_S1.9670.99
196_F233_N1.9630.99
154_R158_E1.9600.99
9_R29_F1.9320.99
342_T400_Q1.9290.99
482_F550_V1.9180.99
420_S464_V1.9150.99
282_Y297_I1.8990.99
112_N139_F1.8840.99
278_L282_Y1.8840.99
311_H317_F1.8690.99
189_F230_A1.8660.99
242_A297_I1.8660.99
254_F278_L1.8620.99
251_G307_R1.8550.99
238_L285_A1.8540.99
549_S591_F1.8420.99
396_D400_Q1.7940.99
304_F309_M1.7870.99
137_P142_V1.7720.99
450_T498_S1.7690.99
239_D293_R1.7680.99
215_L234_V1.7580.99
357_I369_P1.7480.99
216_M284_E1.7480.99
516_D537_K1.7390.99
419_T483_L1.7370.99
29_F32_G1.7350.99
327_E330_K1.7340.99
254_F282_Y1.7270.99
147_S151_A1.7110.98
33_E37_E1.7100.98
674_T683_T1.7020.98
676_N679_E1.6770.98
461_R528_D1.6760.98
315_S451_F1.6580.98
366_K370_N1.6570.98
46_V82_I1.6480.98
74_L144_E1.6430.98
350_L393_K1.6420.98
325_E409_T1.6160.98
68_D71_I1.6150.98
276_A428_G1.5940.98
443_S446_K1.5850.97
521_G537_K1.5810.97
429_L444_L1.5790.97
9_R34_E1.5770.97
283_T428_G1.5750.97
449_I487_Y1.5710.97
220_R284_E1.5690.97
193_A233_N1.5690.97
324_T410_Y1.5670.97
523_Y535_R1.5620.97
427_A485_W1.5450.97
656_I661_T1.5380.97
449_I490_L1.5370.97
74_L78_R1.5290.97
23_H62_A1.5230.97
355_Y394_L1.5150.97
130_K140_V1.5060.97
280_T431_K1.5040.97
351_Y355_Y1.5000.96
344_G348_G1.4810.96
525_T535_R1.4720.96
604_K666_E1.4650.96
53_S412_H1.4630.96
339_I357_I1.4600.96
442_L493_A1.4570.96
548_N578_F1.4550.96
354_V394_L1.4530.96
508_D567_L1.4510.96
95_V533_I1.4500.96
621_I625_Q1.4410.96
296_E300_Q1.4400.96
188_T593_M1.4290.95
559_G562_T1.4280.95
320_L410_Y1.4270.95
513_L526_G1.4200.95
438_E441_Y1.4180.95
114_F139_F1.4160.95
63_H67_E1.4120.95
484_L507_T1.4110.95
231_L289_T1.4090.95
606_I632_D1.3920.95
446_K499_Y1.3880.95
450_T454_N1.3860.95
284_E431_K1.3860.95
523_Y537_K1.3850.94
661_T675_T1.3840.94
116_T120_K1.3820.94
402_L406_E1.3740.94
564_D567_L1.3640.94
516_D523_Y1.3630.94
357_I361_G1.3580.94
559_G568_I1.3470.94
509_D513_L1.3340.93
515_W570_K1.3300.93
339_I352_C1.3260.93
78_R147_S1.3250.93
461_R513_L1.3150.93
221_Y230_A1.3020.92
306_Q440_K1.3020.92
54_T412_H1.2990.92
572_E599_H1.2970.92
305_I309_M1.2970.92
410_Y413_V1.2950.92
491_Y495_F1.2940.92
145_H149_T1.2750.92
552_A595_S1.2740.92
247_Y296_E1.2680.91
326_G409_T1.2680.91
255_A275_N1.2670.91
19_L467_R1.2660.91
47_L75_L1.2660.91
674_T680_A1.2620.91
222_D288_V1.2590.91
279_L432_A1.2590.91
200_Y261_D1.2560.91
189_F221_Y1.2540.91
463_M471_V1.2530.91
451_F455_K1.2510.91
11_I22_A1.2500.91
430_A433_A1.2460.91
334_W404_T1.2400.90
336_K352_C1.2380.90
203_F215_L1.2360.90
279_L428_G1.2340.90
351_Y397_A1.2330.90
298_C432_A1.2320.90
320_L413_V1.2250.90
307_R402_L1.2210.90
24_N62_A1.2170.90
87_E416_K1.2160.90
79_F114_F1.2160.90
114_F123_Y1.2140.90
48_V112_N1.2130.89
502_K505_K1.2100.89
367_N370_N1.2090.89
316_F448_A1.2060.89
302_I444_L1.1990.89
97_M107_G1.1950.89
300_Q398_R1.1920.89
406_E410_Y1.1900.89
303_T440_K1.1900.89
340_L348_G1.1870.88
213_H277_L1.1850.88
486_A490_L1.1840.88
347_L397_A1.1840.88
504_K567_L1.1820.88
114_F146_L1.1800.88
305_I310_T1.1750.88
103_M164_A1.1680.88
347_L400_Q1.1650.87
340_L345_D1.1590.87
339_I351_Y1.1560.87
149_T153_D1.1550.87
24_N67_E1.1540.87
419_T423_A1.1460.87
11_I27_D1.1440.87
251_G402_L1.1430.86
315_S417_V1.1420.86
507_T522_F1.1390.86
310_T444_L1.1370.86
331_Y402_L1.1360.86
302_I441_Y1.1320.86
283_T435_V1.1310.86
552_A574_M1.1300.86
120_K161_A1.1260.86
7_P11_I1.1210.85
38_K41_R1.1210.85
247_Y301_I1.1200.85
299_E441_Y1.1190.85
507_T558_L1.1180.85
679_E682_H1.1040.84
246_I258_S1.1030.84
140_V144_E1.1020.84
485_W489_D1.1020.84
320_L332_Y1.1010.84
504_K564_D1.1000.84
219_L234_V1.1000.84
553_V598_R1.0990.84
247_Y297_I1.0960.84
241_M282_Y1.0950.84
399_Q403_K1.0920.84
100_C113_V1.0900.84
508_D564_D1.0900.84
575_F599_H1.0870.84
224_N597_L1.0840.83
49_S52_Y1.0770.83
350_L390_L1.0750.83
424_L482_F1.0740.83
340_L352_C1.0700.83
442_L446_K1.0700.83
456_L466_Y1.0680.82
264_L368_I1.0680.82
434_K625_Q1.0670.82
299_E436_Y1.0650.82
112_N115_I1.0640.82
347_L393_K1.0630.82
21_H24_N1.0610.82
254_F297_I1.0610.82
21_H52_Y1.0600.82
312_E317_F1.0590.82
38_K44_K1.0570.82
457_I502_K1.0560.82
279_L429_L1.0550.82
620_I662_V1.0530.82
283_T432_A1.0530.82
23_H63_H1.0520.81
498_S502_K1.0500.81
540_Y588_G1.0470.81
539_V578_F1.0460.81
115_I119_Q1.0430.81
365_G370_N1.0400.81
674_T679_E1.0360.80
279_L283_T1.0350.80
29_F34_E1.0340.80
526_G529_A1.0320.80
284_E287_Q1.0300.80
537_K548_N1.0280.80
453_E498_S1.0220.80
655_I661_T1.0190.79
27_D30_P1.0150.79
235_T294_Y1.0130.79
27_D38_K1.0100.79
92_V97_M1.0050.78
148_E153_D1.0040.78
453_E457_I1.0040.78
70_E140_V1.0030.78
193_A229_N1.0030.78
250_I398_R1.0010.78
298_C436_Y0.9990.78
16_P19_L0.9980.78
483_L487_Y0.9970.78
29_F35_A0.9970.78
243_N293_R0.9900.77
629_K632_D0.9860.77
14_K465_R0.9810.77
607_V650_A0.9800.77
488_L567_L0.9780.76
336_K348_G0.9770.76
98_R102_L0.9750.76
249_H402_L0.9740.76
37_E40_K0.9730.76
368_I371_L0.9670.76
449_I486_A0.9660.76
310_T425_M0.9640.75
62_A112_N0.9630.75
100_C104_T0.9610.75
423_A483_L0.9610.75
132_S138_G0.9610.75
450_T499_Y0.9600.75
476_F524_F0.9590.75
217_Y221_Y0.9580.75
207_P261_D0.9560.75
464_V476_F0.9540.75
446_K450_T0.9530.75
484_L510_M0.9530.75
317_F417_V0.9520.75
450_T453_E0.9490.74
395_E399_Q0.9480.74
200_Y262_E0.9480.74
431_K489_D0.9470.74
404_T407_E0.9450.74
551_A554_Q0.9450.74
356_D370_N0.9450.74
666_E671_Q0.9430.74
279_L301_I0.9420.74
291_N294_Y0.9420.74
159_D163_N0.9400.74
442_L494_S0.9380.73
386_T389_E0.9370.73
672_Q679_E0.9290.73
395_E398_R0.9290.73
120_K165_A0.9260.72
287_Q435_V0.9250.72
473_N476_F0.9240.72
439_P443_S0.9230.72
522_F574_M0.9230.72
324_T330_K0.9220.72
222_D225_T0.9210.72
513_L528_D0.9190.72
20_Q24_N0.9170.72
624_L680_A0.9150.72
451_F466_Y0.9120.71
639_Q655_I0.9090.71
364_E368_I0.9040.71
197_D208_K0.9030.71
246_I301_I0.9000.70
556_L599_H0.8980.70
229_N232_Y0.8970.70
17_Y21_H0.8950.70
241_M254_F0.8950.70
250_I369_P0.8940.70
339_I348_G0.8920.70
14_K470_E0.8920.70
318_S421_W0.8920.70
48_V96_Y0.8920.70
419_T456_L0.8920.70
264_L363_F0.8910.70
21_H49_S0.8890.69
474_K526_G0.8870.69
100_C111_L0.8870.69
19_L415_D0.8840.69
620_I624_L0.8830.69
97_M102_L0.8830.69
52_Y416_K0.8820.69
508_D566_S0.8820.69
568_I572_E0.8760.68
330_K333_V0.8740.68
647_A650_A0.8730.68
662_V677_I0.8710.68
306_Q429_L0.8710.68
222_D226_G0.8700.68
99_I164_A0.8700.68
507_T510_M0.8700.68
326_G363_F0.8690.68
478_D524_F0.8690.68
504_K508_D0.8690.68
279_L441_Y0.8680.67
133_K136_R0.8680.67
217_Y590_A0.8680.67
280_T485_W0.8670.67
99_I124_A0.8660.67
57_W60_V0.8650.67
423_A427_A0.8650.67
21_H416_K0.8620.67
516_D519_H0.8600.67
560_Q568_I0.8600.67
664_I674_T0.8600.67
354_V372_I0.8580.67
507_T511_I0.8580.67
228_E232_Y0.8570.66
7_P27_D0.8560.66
113_V124_A0.8560.66
89_R476_F0.8560.66
215_L281_A0.8540.66
283_T302_I0.8520.66
129_P138_G0.8520.66
297_I300_Q0.8520.66
478_D547_G0.8500.66
336_K340_L0.8470.66
78_R143_L0.8470.66
620_I660_T0.8440.65
443_S447_D0.8420.65
75_L139_F0.8420.65
216_M628_F0.8410.65
68_D140_V0.8410.65
30_P35_A0.8400.65
56_H60_V0.8380.65
609_F655_I0.8360.65
13_E472_K0.8360.65
306_Q310_T0.8330.64
623_E681_I0.8220.63
393_K397_A0.8220.63
442_L490_L0.8200.63
9_R35_A0.8200.63
433_A438_E0.8200.63
46_V119_Q0.8190.63
125_G275_N0.8170.63
21_H271_M0.8170.63
358_T361_G0.8170.63
52_Y87_E0.8120.62
286_Y298_C0.8120.62
484_L551_A0.8110.62
238_L281_A0.8110.62
311_H417_V0.8100.62
656_I675_T0.8100.62
477_I510_M0.8080.62
457_I460_G0.8080.62
103_M124_A0.8060.62
99_I103_M0.8050.62
146_L157_V0.8050.62
251_G308_E0.8040.62
504_K562_T0.8040.62
310_T448_A0.8030.61
241_M249_H0.8030.61
160_I164_A0.7970.61
334_W401_L0.7950.61
249_H351_Y0.7940.61
398_R402_L0.7940.61
189_F193_A0.7930.60
242_A254_F0.7920.60
196_F237_T0.7920.60
623_E626_K0.7910.60
364_E369_P0.7900.60
320_L331_Y0.7900.60
21_H87_E0.7890.60
522_F570_K0.7870.60
56_H323_D0.7870.60
258_S262_E0.7850.60
671_Q683_T0.7850.60
279_L298_C0.7830.59
68_D124_A0.7820.59
234_V281_A0.7820.59
97_M105_G0.7800.59
426_I490_L0.7790.59
355_Y398_R0.7780.59
148_E679_E0.7760.59
562_T565_L0.7750.59
336_K359_E0.7730.58
565_L569_E0.7720.58
340_L349_T0.7720.58
510_M513_L0.7720.58
496_D499_Y0.7710.58
656_I659_K0.7690.58
309_M409_T0.7660.58
99_I119_Q0.7650.58
331_Y406_E0.7640.58
299_E440_K0.7640.58
485_W553_V0.7640.58
532_L536_E0.7610.57
279_L425_M0.7610.57
125_G139_F0.7610.57
550_V554_Q0.7580.57
561_V635_L0.7580.57
63_H323_D0.7570.57
49_S57_W0.7540.57
413_V467_R0.7540.57
14_K19_L0.7540.57
386_T390_L0.7500.56
52_Y56_H0.7500.56
316_F425_M0.7480.56
301_I308_E0.7470.56
658_G663_Y0.7470.56
285_A294_Y0.7470.56
206_A255_A0.7460.56
128_F139_F0.7460.56
24_N52_Y0.7460.56
461_R526_G0.7460.56
657_D661_T0.7440.56
36_F54_T0.7430.55
665_C670_C0.7430.55
430_A486_A0.7410.55
432_A436_Y0.7400.55
249_H370_N0.7400.55
231_L235_T0.7400.55
606_I662_V0.7390.55
296_E391_S0.7380.55
489_D557_R0.7370.55
677_I681_I0.7350.55
311_H466_Y0.7340.55
49_S83_K0.7330.54
457_I462_V0.7330.54
250_I351_Y0.7320.54
433_A493_A0.7310.54
138_G141_D0.7310.54
29_F42_E0.7310.54
337_E341_K0.7300.54
364_E367_N0.7290.54
402_L410_Y0.7280.54
358_T367_N0.7260.54
24_N49_S0.7260.54
620_I677_I0.7260.54
32_G36_F0.7260.54
182_E186_H0.7250.54
453_E483_L0.7250.54
581_D589_H0.7250.54
624_L662_V0.7240.54
265_V368_I0.7230.53
259_T363_F0.7230.53
36_F81_A0.7210.53
487_Y502_K0.7190.53
608_I662_V0.7180.53
515_W573_T0.7160.53
656_I663_Y0.7150.53
605_E667_N0.7140.53
462_V475_G0.7120.52
346_D393_K0.7110.52
433_A436_Y0.7090.52
277_L428_G0.7080.52
316_F444_L0.7080.52
647_A651_A0.7070.52
311_H315_S0.7060.52
578_F592_F0.7050.52
307_R331_Y0.7050.52
235_T239_D0.7030.51
449_I506_L0.7030.51
277_L281_A0.7030.51
486_A506_L0.7030.51
419_T487_Y0.7010.51
509_D512_S0.7010.51
189_F217_Y0.7000.51
149_T157_V0.6990.51
418_L465_R0.6980.51
27_D34_E0.6980.51
449_I483_L0.6980.51
350_L397_A0.6980.51
49_S60_V0.6960.51
16_P415_D0.6940.50
156_H160_I0.6940.50
507_T551_A0.6940.50
150_F158_E0.6940.50
141_D145_H0.6910.50
623_E680_A0.6900.50
324_T409_T0.6900.50
216_M281_A0.6890.50
239_D243_N0.6890.50
211_M214_M0.6890.50
221_Y225_T0.6850.50
149_T156_H0.6850.50
275_N420_S0.6840.49
188_T551_A0.6840.49
339_I355_Y0.6790.49
308_E413_V0.6790.49
475_G514_F0.6790.49
56_H59_H0.6780.49
219_L288_V0.6770.49
432_A441_Y0.6770.49
184_A579_K0.6760.49
202_G208_K0.6750.49
43_N151_A0.6750.49
113_V128_F0.6750.49
123_Y145_H0.6740.48
221_Y597_L0.6740.48
433_A494_S0.6740.48
255_A473_N0.6730.48
69_E77_E0.6730.48
475_G482_F0.6720.48
465_R470_E0.6710.48
26_V30_P0.6710.48
70_E73_R0.6710.48
622_A626_K0.6700.48
283_T298_C0.6700.48
623_E677_I0.6700.48
251_G324_T0.6690.48
104_T124_A0.6690.48
664_I680_A0.6690.48
501_Q505_K0.6690.48
344_G400_Q0.6660.48
106_Q136_R0.6640.47
77_E147_S0.6630.47
420_S478_D0.6630.47
426_I483_L0.6620.47
79_F147_S0.6620.47
612_A638_E0.6620.47
302_I428_G0.6610.47
114_F128_F0.6600.47
197_D202_G0.6600.47
77_E345_D0.6590.47
356_D373_H0.6590.47
510_M554_Q0.6580.47
207_P258_S0.6570.47
279_L305_I0.6570.47
242_A252_Y0.6560.47
10_L18_L0.6550.47
43_N117_P0.6550.47
427_A486_A0.6540.46
649_F652_D0.6540.46
357_I367_N0.6520.46
24_N273_Y0.6520.46
130_K138_G0.6510.46
298_C441_Y0.6500.46
280_T428_G0.6500.46
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553_V591_F0.6490.46
52_Y57_W0.6490.46
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553_V595_S0.6470.46
24_N53_S0.6460.46
569_E573_T0.6460.46
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52_Y66_F0.6430.45
132_S137_P0.6420.45
231_L288_V0.6420.45
132_S135_N0.6410.45
487_Y499_Y0.6400.45
235_T285_A0.6400.45
132_S140_V0.6400.45
48_V111_L0.6380.45
21_H53_S0.6380.45
120_K158_E0.6380.45
20_Q53_S0.6370.45
78_R81_A0.6370.45
457_I509_D0.6360.45
52_Y55_C0.6350.44
168_L534_V0.6340.44
452_I462_V0.6340.44
189_F233_N0.6330.44
607_V649_F0.6320.44
275_N364_E0.6320.44
25_P49_S0.6310.44
602_P666_E0.6310.44
192_L214_M0.6310.44
272_L425_M0.6300.44
350_L394_L0.6290.44
92_V115_I0.6290.44
283_T287_Q0.6280.44
390_L397_A0.6270.44
8_N18_L0.6270.44
75_L465_R0.6270.44
457_I505_K0.6270.44
287_Q628_F0.6260.44
497_L501_Q0.6260.44
267_H271_M0.6260.44
259_T546_S0.6250.43
53_S450_T0.6250.43
74_L143_L0.6240.43
335_S338_E0.6240.43
347_L396_D0.6240.43
17_Y271_M0.6230.43
189_F227_Q0.6230.43
18_L21_H0.6230.43
419_T463_M0.6220.43
100_C332_Y0.6210.43
49_S271_M0.6210.43
252_Y303_T0.6200.43
60_V83_K0.6190.43
162_E166_K0.6190.43
133_K137_P0.6190.43
596_V600_L0.6180.43
548_N552_A0.6180.43
18_L49_S0.6180.43
201_G240_S0.6170.43
10_L60_V0.6170.43
415_D469_G0.6170.43
51_G56_H0.6170.43
29_F36_F0.6160.43
9_R30_P0.6150.42
250_I357_I0.6150.42
455_K466_Y0.6150.42
662_V674_T0.6140.42
451_F456_L0.6140.42
566_S570_K0.6130.42
193_A227_Q0.6130.42
264_L371_L0.6130.42
49_S87_E0.6130.42
30_P33_E0.6130.42
223_H630_P0.6130.42
16_P24_N0.6120.42
83_K273_Y0.6110.42
492_E561_V0.6110.42
161_A165_A0.6110.42
430_A490_L0.6110.42
95_V532_L0.6100.42
55_C60_V0.6100.42
93_D267_H0.6090.42
51_G58_C0.6090.42
475_G483_L0.6090.42
135_N138_G0.6090.42
658_G664_I0.6080.42
89_R95_V0.6070.42
215_L237_T0.6060.42
36_F119_Q0.6060.42
306_Q316_F0.6060.42
426_I449_I0.6060.42
163_N166_K0.6060.42
558_L567_L0.6060.42
273_Y421_W0.6060.42
44_K80_V0.6050.41
131_T140_V0.6050.41
426_I452_I0.6050.41
257_Y267_H0.6040.41
512_S566_S0.6040.41
521_G578_F0.6040.41
21_H54_T0.6040.41
101_Q104_T0.6030.41
155_E158_E0.6020.41
55_C58_C0.6010.41
244_G258_S0.6000.41
301_I320_L0.6000.41
275_N370_N0.6000.41
640_P645_D0.5990.41
426_I486_A0.5990.41
611_S660_T0.5990.41
265_V364_E0.5990.41
100_C125_G0.5980.41
663_Y673_P0.5980.41
458_I463_M0.5980.41
145_H148_E0.5980.41
107_G125_G0.5960.41
303_T306_Q0.5950.40
658_G661_T0.5950.40
303_T307_R0.5940.40
131_T141_D0.5940.40
106_Q428_G0.5940.40
140_V259_T0.5940.40
48_V543_A0.5940.40
624_L629_K0.5920.40
26_V81_A0.5920.40
303_T441_Y0.5920.40
203_F233_N0.5920.40
632_D664_I0.5920.40
105_G203_F0.5910.40
358_T362_N0.5900.40
264_L358_T0.5890.40
286_Y289_T0.5880.40
205_Q261_D0.5880.40
358_T363_F0.5880.40
62_A66_F0.5870.40
309_M319_A0.5870.40
327_E365_G0.5850.40
454_N523_Y0.5850.40
43_N158_E0.5840.39
452_I483_L0.5840.39
63_H102_L0.5830.39
55_C93_D0.5820.39
235_T289_T0.5810.39
52_Y273_Y0.5810.39
252_Y398_R0.5810.39
63_H258_S0.5800.39
35_A38_K0.5760.39
282_Y285_A0.5730.38
556_L595_S0.5730.38
401_L405_R0.5720.38
35_A80_V0.5720.38
375_K390_L0.5710.38
24_N416_K0.5700.38
570_K573_T0.5700.38
97_M101_Q0.5700.38
17_Y49_S0.5690.38
48_V84_V0.5690.38
87_E97_M0.5670.38
36_F75_L0.5660.38
107_G126_T0.5660.38
624_L634_I0.5650.38
388_K391_S0.5640.37
336_K363_F0.5630.37
259_T342_T0.5630.37
485_W554_Q0.5630.37
43_N450_T0.5620.37
308_E410_Y0.5620.37
546_S549_S0.5610.37
81_A240_S0.5610.37
54_T275_N0.5610.37
580_P584_A0.5600.37
112_N543_A0.5600.37
611_S638_E0.5590.37
21_H273_Y0.5580.37
55_C267_H0.5580.37
542_G588_G0.5580.37
9_R32_G0.5580.37
10_L49_S0.5570.37
346_D678_E0.5560.37
52_Y97_M0.5550.37
334_W411_P0.5550.37
97_M542_G0.5550.37
16_P21_H0.5540.37
287_Q630_P0.5540.37
242_A249_H0.5520.36
27_D35_A0.5520.36
355_Y667_N0.5510.36
273_Y416_K0.5510.36
298_C301_I0.5500.36
524_F536_E0.5500.36
356_D371_L0.5500.36
423_A487_Y0.5500.36
677_I680_A0.5500.36
465_R473_N0.5490.36
492_E632_D0.5490.36
49_S53_S0.5490.36
49_S55_C0.5480.36
363_F368_I0.5480.36
264_L370_N0.5480.36
118_D657_D0.5470.36
255_A332_Y0.5470.36
7_P12_N0.5460.36
449_I502_K0.5460.36
264_L369_P0.5460.36
242_A293_R0.5460.36
585_Y588_G0.5450.36
79_F143_L0.5450.36
13_E402_L0.5440.36
330_K363_F0.5440.36
276_A425_M0.5440.36
333_V357_I0.5440.36
41_R80_V0.5430.35
304_F308_E0.5430.35
350_L354_V0.5430.35
93_D256_R0.5430.35
228_E235_T0.5430.35
464_V544_V0.5420.35
431_K434_K0.5410.35
624_L681_I0.5400.35
286_Y295_K0.5400.35
97_M211_M0.5390.35
17_Y24_N0.5390.35
119_Q464_V0.5390.35
610_G660_T0.5390.35
230_A234_V0.5390.35
123_Y593_M0.5380.35
216_M591_F0.5380.35
430_A434_K0.5380.35
578_F581_D0.5380.35
50_I178_E0.5370.35
575_F600_L0.5370.35
357_I370_N0.5370.35
20_Q52_Y0.5370.35
582_I593_M0.5370.35
488_L667_N0.5370.35
279_L303_T0.5370.35
122_F316_F0.5360.35
430_A489_D0.5360.35
61_M83_K0.5350.35
201_G208_K0.5350.35
669_A672_Q0.5350.35
236_K293_R0.5340.35
45_P114_F0.5330.35
160_I585_Y0.5330.35
62_A331_Y0.5330.35
15_S18_L0.5320.34
607_V637_A0.5320.34
55_C59_H0.5320.34
105_G276_A0.5310.34
330_K491_Y0.5310.34
507_T567_L0.5310.34
304_F500_L0.5300.34
18_L25_P0.5300.34
190_Q193_A0.5300.34
52_Y60_V0.5290.34
196_F203_F0.5280.34
485_W550_V0.5280.34
67_E112_N0.5280.34
82_I407_E0.5280.34
466_Y471_V0.5270.34
667_N671_Q0.5260.34
93_D209_F0.5260.34
331_Y409_T0.5260.34
522_F548_N0.5250.34
327_E409_T0.5250.34
446_K494_S0.5250.34
546_S552_A0.5240.34
11_I29_F0.5240.34
14_K301_I0.5240.34
31_W57_W0.5230.34
490_L493_A0.5230.34
619_Q678_E0.5230.34
137_P141_D0.5220.34
24_N271_M0.5220.34
265_V333_V0.5220.34
178_E622_A0.5210.33
185_I597_L0.5200.33
50_I511_I0.5200.33
17_Y25_P0.5190.33
420_S482_F0.5190.33
611_S677_I0.5190.33
389_E512_S0.5180.33
115_I139_F0.5180.33
325_E331_Y0.5180.33
598_R602_P0.5180.33
154_R157_V0.5180.33
468_D471_V0.5170.33
256_R267_H0.5170.33
16_P467_R0.5160.33
556_L575_F0.5160.33
54_T87_E0.5160.33
488_L558_L0.5150.33
84_V92_V0.5150.33
215_L276_A0.5140.33
423_A426_I0.5130.33
529_A532_L0.5130.33
319_A582_I0.5130.33
53_S416_K0.5130.33
178_E580_P0.5120.33
434_K493_A0.5110.33
73_R78_R0.5110.33
29_F41_R0.5110.33
94_S464_V0.5110.33
47_L139_F0.5100.32
114_F122_F0.5100.32
71_I74_L0.5100.32
53_S57_W0.5100.32
79_F239_D0.5100.32
150_F683_T0.5100.32
606_I610_G0.5100.32
122_F157_V0.5100.32
219_L285_A0.5090.32
100_C213_H0.5090.32
491_Y500_L0.5090.32
340_L344_G0.5090.32
52_Y62_A0.5090.32
14_K468_D0.5090.32
33_E530_E0.5080.32
635_L649_F0.5080.32
662_V675_T0.5070.32
19_L23_H0.5070.32
302_I425_M0.5070.32
319_A591_F0.5070.32
87_E418_L0.5070.32
674_T681_I0.5070.32
467_R522_F0.5060.32
304_F636_V0.5050.32
602_P671_Q0.5050.32
40_K46_V0.5040.32
298_C624_L0.5040.32
264_L330_K0.5040.32
32_G82_I0.5040.32
255_A412_H0.5040.32
10_L31_W0.5030.32
271_M416_K0.5030.32
51_G60_V0.5020.32
211_M590_A0.5020.32
258_S323_D0.5020.32
47_L81_A0.5020.32
345_D349_T0.5020.32
252_Y301_I0.5010.32
21_H25_P0.5010.32
299_E303_T0.5010.32
488_L554_Q0.5010.32
427_A430_A0.5010.32
610_G662_V0.5010.32
448_A451_F0.5000.32
166_K600_L0.5000.32
212_P278_L0.5000.32
215_L250_I0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3vw5A 1 0.5109 100 0.826 Contact Map
3wkgA 1 0.5283 100 0.826 Contact Map
1fp3A 2 0.4964 100 0.827 Contact Map
4c1sA 1 0.4877 100 0.827 Contact Map
2ahfA 1 0.4891 100 0.841 Contact Map
3gt5A 1 0.5341 100 0.844 Contact Map
2gz6A 2 0.5065 100 0.844 Contact Map
4v1sA 1 0.4862 100 0.847 Contact Map
5agdA 1 0.4688 100 0.849 Contact Map
2zzrA 1 0.5385 100 0.849 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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