GREMLIN Database
YYAO - Uncharacterized protein YyaO
UniProt: P37509 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 79 (67)
Sequences: 1324 (422)
Seq/√Len: 51.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
38_K42_E3.2521.00
13_E30_P3.1381.00
32_G35_A2.7041.00
9_R29_F2.4711.00
37_A41_R2.3391.00
24_N63_I2.2491.00
29_F38_K2.1851.00
70_L74_R2.1571.00
36_F46_V2.0391.00
7_P23_H1.9811.00
29_F32_G1.7490.99
11_I23_H1.6140.98
24_N68_T1.6000.98
21_H52_Y1.5470.97
64_K68_T1.5340.97
38_K41_R1.4280.96
9_R27_D1.3980.95
33_E37_A1.3390.94
9_R34_E1.3260.94
14_K47_L1.3230.94
14_K19_L1.2100.90
16_P19_L1.1820.89
7_P11_I1.1700.89
52_Y55_T1.1450.88
69_P72_D1.1090.86
19_L22_A1.1080.86
16_P55_T1.1060.86
66_C72_D1.0910.85
16_P31_W1.0680.84
7_P27_D1.0410.82
21_H55_T1.0200.81
29_F35_A1.0110.80
49_S52_Y0.9880.79
9_R32_G0.9850.78
9_R35_A0.9800.78
36_F55_T0.9770.78
20_Q60_P0.9590.76
45_P63_I0.9310.74
52_Y67_G0.9040.72
49_S67_G0.8930.71
63_I67_G0.8860.71
21_H49_S0.8840.70
14_K55_T0.8800.70
49_S63_I0.8680.69
21_H24_N0.8600.68
21_H67_G0.8510.67
20_Q53_S0.8480.67
12_A37_A0.8370.66
35_A48_V0.8300.66
27_D38_K0.8270.65
20_Q64_K0.8180.64
60_P66_C0.8070.63
11_I22_A0.7910.62
37_A40_K0.7840.61
24_N53_S0.7320.56
11_I27_D0.7270.55
43_N64_K0.7210.55
40_K43_N0.7200.55
71_K74_R0.7060.53
37_A74_R0.6980.52
11_I19_L0.6860.51
47_L55_T0.6810.51
24_N52_Y0.6760.50
41_R74_R0.6710.50
24_N50_I0.6650.49
52_Y56_C0.6600.48
35_A38_K0.6560.48
20_Q68_T0.6550.48
18_L30_P0.6550.48
55_T64_K0.6490.47
55_T66_C0.6420.46
29_F36_F0.6330.46
10_L18_L0.6250.45
42_E45_P0.6250.45
12_A40_K0.6220.44
9_R30_P0.6180.44
17_Y50_I0.6060.43
52_Y63_I0.6060.43
49_S55_T0.6020.42
22_A49_S0.5920.41
53_S67_G0.5750.40
16_P24_N0.5750.40
25_P68_T0.5720.39
51_G58_W0.5670.39
59_W62_I0.5630.38
21_H53_S0.5610.38
62_I73_N0.5570.38
52_Y57_H0.5560.38
8_N31_W0.5540.38
47_L66_C0.5510.37
21_H56_C0.5400.36
13_E19_L0.5350.36
40_K50_I0.5330.36
17_Y21_H0.5330.36
28_W51_G0.5270.35
26_V66_C0.5240.35
12_A41_R0.5210.34
23_H63_I0.5070.33
7_P33_E0.5030.33
29_F72_D0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3iraA 1 0.9241 99.1 0.704 Contact Map
2ec4A 1 0.9241 98.3 0.774 Contact Map
2dlxA 1 0.8987 96.3 0.84 Contact Map
3ph9A 1 0.8101 95.5 0.851 Contact Map
2lstA 1 0.6709 95.2 0.853 Contact Map
2ju5A 1 0.8987 94.9 0.856 Contact Map
3fk8A 1 0.7722 93.6 0.865 Contact Map
3f9uA 2 0.7089 93.2 0.867 Contact Map
1oazA 1 0.5949 93 0.868 Contact Map
2kucA 1 0.7215 92.2 0.871 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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