SYK - BACSU - GREMLIN Contacts

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SYK - Lysine--tRNA ligase

UniProt:	P37477	Sequences: MSQEEHNHEELNDQLQVRRDKMNQLRDNGIDPFGARFERTHQSQEVISAYQDLTKEELEEKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRKDSVGDDQYEIFKSSDLGDLIGVTGKVFKTNVGELSVKATSFELLTKALRPLPDKYHGLKDVEQRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTMHSIPGGASARPFITHHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMSLTENLVAHIAQEVLGTTTIQYGEEQIDLKPEWKRIHMVDAVKEATGVDFWEEVTVEQAREYAKEHEVEIKDSMTVGHIINEFFEQKIEETLIQPTFIYGHPVEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKEREAGNDEAHLMDEDFVEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMRQR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	499 (429)
Sequences:	9639 (4758)
Seq/√Len:	229.7

ECOLI - SYK1 SYK2 SYN SYD EPMA
BACSU - SYK SYN SYDND
HALSA - SYDND
SULSO - SYK SYDND

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
197_H	292_N	4.564	1.00
121_T	138_S	3.966	1.00
94_I	136_A	3.794	1.00
195_D	252_Y	3.693	1.00
60_E	63_I	3.692	1.00
66_T	121_T	3.621	1.00
64_E	121_T	3.588	1.00
193_Y	292_N	3.528	1.00
188_Q	192_R	3.504	1.00
192_R	196_D	3.328	1.00
64_E	137_T	3.292	1.00
188_Q	195_D	3.238	1.00
240_L	251_V	2.987	1.00
119_G	140_E	2.945	1.00
189_A	300_E	2.846	1.00
189_A	296_H	2.805	1.00
281_A	285_D	2.780	1.00
423_T	468_G	2.657	1.00
182_T	482_T	2.503	1.00
331_E	342_T	2.459	1.00
206_T	258_F	2.361	1.00
348_E	352_E	2.338	1.00
94_I	120_V	2.330	1.00
244_I	467_T	2.312	1.00
190_M	274_I	2.285	1.00
387_G	399_N	2.258	1.00
369_E	373_Q	2.249	1.00
146_L	461_E	2.222	1.00
68_A	119_G	2.215	1.00
186_I	478_V	2.182	1.00
92_I	134_V	2.157	1.00
220_I	229_P	2.063	1.00
206_T	255_G	2.057	1.00
187_I	474_I	2.055	1.00
191_R	201_E	2.055	1.00
413_I	418_H	2.052	1.00
64_E	123_K	2.037	1.00
62_A	123_K	2.002	1.00
123_K	137_T	1.982	1.00
192_R	195_D	1.982	1.00
184_S	195_D	1.956	1.00
295_A	318_P	1.953	1.00
65_V	134_V	1.953	1.00
324_H	327_D	1.945	1.00
296_H	300_E	1.944	1.00
192_R	300_E	1.939	1.00
179_T	484_A	1.923	1.00
432_R	436_E	1.922	1.00
193_Y	296_H	1.918	1.00
278_E	281_A	1.912	1.00
193_Y	197_H	1.909	1.00
288_S	292_N	1.878	1.00
348_E	351_K	1.873	1.00
283_Y	407_D	1.873	1.00
190_M	293_L	1.866	1.00
433_E	437_A	1.836	1.00
193_Y	293_L	1.833	1.00
286_I	468_G	1.827	1.00
384_F	411_L	1.827	1.00
400_P	407_D	1.823	1.00
276_L	470_L	1.801	1.00
327_D	331_E	1.787	1.00
189_A	297_I	1.777	1.00
428_P	432_R	1.776	1.00
324_H	387_G	1.762	1.00
125_F	135_K	1.751	1.00
196_D	296_H	1.732	1.00
67_I	92_I	1.726	1.00
399_N	407_D	1.717	1.00
294_V	411_L	1.692	1.00
202_V	243_L	1.686	1.00
282_D	285_D	1.682	1.00
177_K	181_I	1.665	1.00
86_Q	91_Q	1.641	1.00
376_E	379_L	1.637	1.00
181_I	200_L	1.635	1.00
433_E	436_E	1.615	1.00
432_R	457_V	1.588	1.00
199_Y	278_E	1.587	1.00
66_T	119_G	1.577	1.00
428_P	461_E	1.567	1.00
178_H	182_T	1.558	1.00
71_M	112_S	1.550	1.00
71_M	118_I	1.535	1.00
84_H	91_Q	1.534	1.00
398_K	427_D	1.515	1.00
81_G	106_Y	1.506	1.00
323_I	328_A	1.505	1.00
306_T	315_D	1.504	1.00
123_K	135_K	1.488	1.00
198_G	250_K	1.486	1.00
437_A	440_K	1.482	1.00
185_K	188_Q	1.469	1.00
278_E	289_L	1.459	1.00
71_M	83_A	1.459	1.00
298_A	481_L	1.440	1.00
162_R	169_D	1.438	1.00
368_N	372_E	1.438	1.00
423_T	426_N	1.436	1.00
185_K	300_E	1.428	1.00
345_Q	348_E	1.426	1.00
398_K	430_D	1.413	1.00
186_I	297_I	1.413	1.00
326_V	330_K	1.400	1.00
57_E	60_E	1.396	1.00
136_A	139_F	1.393	1.00
284_K	288_S	1.389	1.00
257_V	273_M	1.388	1.00
174_P	178_H	1.386	1.00
284_K	322_R	1.385	1.00
342_T	345_Q	1.379	1.00
343_V	347_R	1.376	1.00
61_K	126_K	1.368	1.00
180_F	248_L	1.363	1.00
175_D	484_A	1.354	1.00
299_Q	303_G	1.352	1.00
189_A	192_R	1.349	1.00
327_D	330_K	1.336	1.00
281_A	468_G	1.331	1.00
112_S	118_I	1.327	1.00
274_I	474_I	1.319	1.00
458_E	461_E	1.318	1.00
323_I	385_I	1.317	1.00
103_D	107_E	1.314	1.00
432_R	454_E	1.302	1.00
189_A	301_V	1.299	1.00
450_H	458_E	1.299	1.00
219_F	225_A	1.299	1.00
427_D	430_D	1.299	1.00
402_D	405_F	1.295	1.00
375_I	379_L	1.294	1.00
390_V	434_R	1.289	1.00
67_I	85_L	1.285	1.00
185_K	305_T	1.284	1.00
194_L	274_I	1.276	1.00
250_K	278_E	1.274	1.00
321_K	381_Q	1.271	1.00
411_L	419_A	1.267	1.00
363_V	367_I	1.265	1.00
54_T	57_E	1.264	1.00
119_G	142_L	1.240	1.00
120_V	136_A	1.238	1.00
124_V	132_L	1.236	1.00
192_R	296_H	1.232	1.00
180_F	492_L	1.228	1.00
181_I	185_K	1.227	1.00
165_Q	458_E	1.223	1.00
332_A	378_T	1.222	1.00
321_K	331_E	1.219	1.00
79_K	98_K	1.218	1.00
236_I	257_V	1.201	1.00
441_E	451_L	1.198	1.00
288_S	340_E	1.197	1.00
178_H	181_I	1.196	1.00
326_V	405_F	1.194	1.00
434_R	437_A	1.187	1.00
194_L	276_L	1.187	1.00
80_A	95_Y	1.176	1.00
430_D	433_E	1.168	1.00
182_T	301_V	1.166	1.00
396_A	422_F	1.161	1.00
124_V	134_V	1.159	1.00
73_T	84_H	1.150	1.00
152_K	155_G	1.149	1.00
190_M	474_I	1.136	1.00
177_K	248_L	1.136	1.00
432_R	450_H	1.131	1.00
222_H	227_D	1.130	1.00
96_V	136_A	1.129	1.00
194_L	293_L	1.125	1.00
112_S	139_F	1.124	1.00
222_H	229_P	1.121	1.00
399_N	405_F	1.116	1.00
83_A	94_I	1.115	1.00
186_I	481_L	1.110	1.00
364_G	367_I	1.106	1.00
202_V	248_L	1.105	1.00
190_M	297_I	1.098	1.00
151_D	155_G	1.094	1.00
290_T	472_I	1.093	1.00
236_I	273_M	1.088	1.00
207_M	221_T	1.086	1.00
201_E	252_Y	1.086	1.00
390_V	398_K	1.082	1.00
262_G	497_R	1.080	1.00
291_E	295_A	1.079	1.00
113_D	116_D	1.073	1.00
224_N	227_D	1.071	1.00
151_D	154_H	1.069	1.00
72_M	86_Q	1.067	1.00
67_I	134_V	1.064	1.00
185_K	195_D	1.063	1.00
52_D	89_E	1.055	1.00
197_H	289_L	1.055	1.00
441_E	450_H	1.053	1.00
362_T	365_H	1.053	1.00
294_V	477_L	1.052	1.00
238_L	455_D	1.048	1.00
292_N	295_A	1.048	1.00
297_I	301_V	1.046	1.00
87_D	90_G	1.046	1.00
328_A	385_I	1.046	1.00
186_I	474_I	1.044	1.00
85_L	118_I	1.044	1.00
89_E	92_I	1.044	1.00
97_R	100_S	1.038	1.00
86_Q	115_G	1.038	1.00
49_A	63_I	1.031	1.00
382_P	413_I	1.030	1.00
170_L	180_F	1.028	1.00
299_Q	305_T	1.025	1.00
291_E	340_E	1.025	1.00
203_E	256_R	1.020	1.00
441_E	452_M	1.016	1.00
191_R	252_Y	1.015	1.00
97_R	135_K	1.013	1.00
107_E	110_K	1.011	1.00
432_R	461_E	1.011	1.00
434_R	438_Q	1.009	1.00
112_S	141_L	1.009	1.00
83_A	118_I	1.005	1.00
207_M	230_L	1.002	1.00
484_A	489_D	0.990	1.00
182_T	186_I	0.990	1.00
56_E	60_E	0.989	1.00
105_Q	108_I	0.989	1.00
332_A	342_T	0.985	1.00
281_A	286_I	0.983	1.00
245_V	464_M	0.983	1.00
484_A	490_V	0.977	1.00
111_S	144_K	0.974	1.00
236_I	255_G	0.970	1.00
287_M	322_R	0.969	1.00
346_A	350_A	0.968	1.00
149_L	153_Y	0.967	1.00
182_T	185_K	0.966	1.00
236_I	239_H	0.965	1.00
293_L	297_I	0.961	1.00
143_T	464_M	0.961	1.00
89_E	249_E	0.960	1.00
319_E	322_R	0.958	1.00
266_R	416_R	0.957	1.00
368_N	392_I	0.956	1.00
329_V	367_I	0.954	1.00
100_S	137_T	0.952	1.00
292_N	296_H	0.952	1.00
295_A	317_K	0.949	1.00
158_D	161_Q	0.949	1.00
290_T	470_L	0.946	1.00
187_I	201_E	0.941	1.00
285_D	288_S	0.935	1.00
184_S	188_Q	0.933	1.00
387_G	405_F	0.931	1.00
100_S	135_K	0.928	1.00
193_Y	289_L	0.924	1.00
362_T	391_E	0.924	1.00
67_I	120_V	0.921	1.00
92_I	124_V	0.919	1.00
464_M	467_T	0.919	1.00
300_E	304_T	0.918	1.00
242_R	493_F	0.915	1.00
428_P	457_V	0.914	1.00
351_K	362_T	0.913	1.00
65_V	124_V	0.912	1.00
106_Y	110_K	0.911	1.00
117_L	143_T	0.907	0.99
72_M	91_Q	0.906	0.99
299_Q	315_D	0.900	0.99
398_K	426_N	0.898	0.99
454_E	458_E	0.897	0.99
344_E	348_E	0.896	0.99
351_K	357_I	0.896	0.99
96_V	109_F	0.892	0.99
338_W	381_Q	0.891	0.99
187_I	274_I	0.887	0.99
440_K	449_A	0.887	0.99
305_T	317_K	0.886	0.99
88_L	181_I	0.879	0.99
243_L	492_L	0.878	0.99
116_D	144_K	0.878	0.99
167_Y	458_E	0.877	0.99
286_I	470_L	0.874	0.99
290_T	419_A	0.872	0.99
122_G	134_V	0.866	0.99
283_Y	287_M	0.864	0.99
276_L	290_T	0.863	0.99
323_I	383_T	0.863	0.99
295_A	305_T	0.853	0.99
175_D	179_T	0.851	0.99
182_T	302_L	0.850	0.99
436_E	450_H	0.849	0.99
113_D	144_K	0.844	0.99
211_P	451_L	0.844	0.99
53_L	56_E	0.843	0.99
435_F	453_D	0.843	0.99
441_E	448_E	0.842	0.99
70_R	280_Y	0.839	0.99
77_K	80_A	0.838	0.99
199_Y	250_K	0.838	0.99
244_I	464_M	0.838	0.99
328_A	331_E	0.835	0.99
291_E	322_R	0.833	0.99
50_Y	63_I	0.833	0.99
425_L	430_D	0.829	0.99
245_V	460_L	0.825	0.99
472_I	477_L	0.824	0.99
76_G	81_G	0.818	0.99
242_R	459_A	0.817	0.99
479_M	487_I	0.817	0.99
342_T	386_Y	0.816	0.99
440_K	453_D	0.814	0.99
357_I	361_M	0.813	0.99
209_S	239_H	0.813	0.99
67_I	94_I	0.812	0.99
220_I	231_Y	0.810	0.99
341_V	368_N	0.808	0.99
418_H	477_L	0.806	0.99
300_E	303_G	0.805	0.99
297_I	300_E	0.804	0.99
206_T	236_I	0.802	0.99
358_K	361_M	0.797	0.99
416_R	480_L	0.796	0.99
184_S	252_Y	0.794	0.99
281_A	289_L	0.791	0.99
76_G	79_K	0.789	0.99
197_H	250_K	0.788	0.99
126_K	131_E	0.786	0.99
179_T	482_T	0.785	0.99
223_H	230_L	0.784	0.99
276_L	286_I	0.783	0.99
356_E	360_S	0.783	0.99
349_Y	352_E	0.782	0.98
120_V	134_V	0.780	0.98
150_P	153_Y	0.778	0.98
429_I	432_R	0.778	0.98
189_A	193_Y	0.777	0.98
186_I	301_V	0.776	0.98
104_D	107_E	0.774	0.98
117_L	465_P	0.774	0.98
387_G	407_D	0.774	0.98
83_A	96_V	0.773	0.98
390_V	406_T	0.771	0.98
330_K	334_G	0.768	0.98
393_S	408_R	0.768	0.98
108_I	111_S	0.767	0.98
320_W	411_L	0.767	0.98
361_M	365_H	0.765	0.98
74_K	81_G	0.763	0.98
349_Y	353_H	0.760	0.98
330_K	345_Q	0.760	0.98
283_Y	387_G	0.760	0.98
429_I	433_E	0.758	0.98
375_I	378_T	0.757	0.98
108_I	139_F	0.756	0.98
287_M	386_Y	0.755	0.98
397_K	426_N	0.750	0.98
370_F	374_K	0.747	0.98
320_W	382_P	0.745	0.98
296_H	299_Q	0.743	0.98
127_T	131_E	0.741	0.98
52_D	92_I	0.738	0.98
385_I	412_F	0.737	0.98
397_K	400_P	0.737	0.98
425_L	434_R	0.735	0.98
350_A	366_I	0.735	0.98
364_G	368_N	0.734	0.98
86_Q	174_P	0.733	0.98
211_P	235_A	0.733	0.98
173_N	176_S	0.733	0.98
388_H	412_F	0.733	0.98
83_A	136_A	0.733	0.98
107_E	111_S	0.726	0.98
334_G	364_G	0.722	0.97
281_A	423_T	0.722	0.97
343_V	363_V	0.720	0.97
409_F	421_A	0.719	0.97
449_A	457_V	0.718	0.97
368_N	371_F	0.715	0.97
345_Q	349_Y	0.713	0.97
408_R	420_N	0.711	0.97
73_T	114_L	0.710	0.97
397_K	407_D	0.710	0.97
355_V	378_T	0.710	0.97
454_E	457_V	0.709	0.97
141_L	144_K	0.707	0.97
298_A	316_L	0.707	0.97
301_V	481_L	0.706	0.97
314_I	414_V	0.706	0.97
254_I	474_I	0.705	0.97
206_T	256_R	0.705	0.97
318_P	322_R	0.705	0.97
287_M	384_F	0.705	0.97
276_L	289_L	0.702	0.97
56_E	132_L	0.702	0.97
482_T	490_V	0.697	0.97
94_I	118_I	0.696	0.97
347_R	351_K	0.694	0.97
291_E	319_E	0.691	0.97
440_K	452_M	0.690	0.97
323_I	331_E	0.689	0.97
53_L	57_E	0.689	0.97
265_T	486_S	0.688	0.97
167_Y	462_Y	0.686	0.97
62_A	126_K	0.686	0.97
105_Q	139_F	0.683	0.96
365_H	368_N	0.683	0.96
290_T	409_F	0.682	0.96
184_S	200_L	0.680	0.96
88_L	249_E	0.679	0.96
333_T	337_F	0.679	0.96
85_L	94_I	0.678	0.96
283_Y	399_N	0.678	0.96
163_Y	489_D	0.678	0.96
182_T	478_V	0.677	0.96
194_L	289_L	0.676	0.96
116_D	141_L	0.676	0.96
176_S	489_D	0.674	0.96
478_V	482_T	0.673	0.96
117_L	280_Y	0.671	0.96
244_I	279_A	0.671	0.96
430_D	434_R	0.670	0.96
295_A	319_E	0.670	0.96
204_T	253_E	0.669	0.96
166_R	170_L	0.669	0.96
144_K	427_D	0.667	0.96
185_K	304_T	0.666	0.96
317_K	321_K	0.666	0.96
344_E	363_V	0.666	0.96
154_H	175_D	0.666	0.96
439_L	452_M	0.666	0.96
168_L	458_E	0.664	0.96
378_T	483_N	0.663	0.96
71_M	74_K	0.661	0.96
391_E	404_R	0.658	0.96
176_S	179_T	0.657	0.96
411_L	472_I	0.655	0.96
263_V	496_M	0.653	0.95
407_D	423_T	0.650	0.95
121_T	137_T	0.649	0.95
169_D	173_N	0.649	0.95
161_Q	165_Q	0.648	0.95
299_Q	302_L	0.648	0.95
144_K	429_I	0.647	0.95
187_I	203_E	0.646	0.95
393_S	422_F	0.646	0.95
314_I	380_I	0.646	0.95
289_L	292_N	0.645	0.95
183_R	203_E	0.645	0.95
100_S	123_K	0.645	0.95
127_T	130_G	0.644	0.95
298_A	380_I	0.644	0.95
353_H	370_F	0.642	0.95
74_K	114_L	0.642	0.95
83_A	109_F	0.642	0.95
97_R	125_F	0.640	0.95
174_P	177_K	0.639	0.95
51_Q	55_K	0.637	0.95
284_K	287_M	0.637	0.95
224_N	229_P	0.637	0.95
398_K	425_L	0.637	0.95
52_D	55_K	0.636	0.95
369_E	372_E	0.635	0.95
51_Q	60_E	0.634	0.95
74_K	83_A	0.633	0.95
96_V	139_F	0.628	0.94
282_D	423_T	0.626	0.94
98_K	106_Y	0.625	0.94
61_K	132_L	0.624	0.94
192_R	304_T	0.624	0.94
200_L	248_L	0.624	0.94
373_Q	377_E	0.624	0.94
342_T	387_G	0.623	0.94
295_A	299_Q	0.622	0.94
286_I	290_T	0.622	0.94
330_K	336_D	0.621	0.94
338_W	341_V	0.621	0.94
328_A	332_A	0.621	0.94
401_E	404_R	0.618	0.94
109_F	139_F	0.618	0.94
349_Y	379_L	0.617	0.94
325_M	329_V	0.616	0.94
355_V	358_K	0.615	0.94
286_I	289_L	0.615	0.94
419_A	472_I	0.614	0.94
426_N	464_M	0.614	0.94
295_A	320_W	0.613	0.94
197_H	296_H	0.612	0.94
294_V	472_I	0.609	0.93
63_I	124_V	0.608	0.93
294_V	320_W	0.607	0.93
149_L	152_K	0.605	0.93
448_E	452_M	0.605	0.93
318_P	324_H	0.604	0.93
203_E	272_T	0.603	0.93
416_R	486_S	0.602	0.93
278_E	285_D	0.602	0.93
194_L	470_L	0.601	0.93
175_D	489_D	0.601	0.93
410_E	420_N	0.597	0.93
399_N	402_D	0.595	0.93
204_T	240_L	0.595	0.93
323_I	327_D	0.594	0.93
302_L	314_I	0.594	0.93
147_R	461_E	0.593	0.93
370_F	373_Q	0.591	0.92
330_K	333_T	0.591	0.92
149_L	155_G	0.590	0.92
399_N	404_R	0.588	0.92
328_A	375_I	0.587	0.92
204_T	236_I	0.585	0.92
89_E	181_I	0.585	0.92
399_N	403_P	0.584	0.92
98_K	103_D	0.584	0.92
75_R	84_H	0.583	0.92
371_F	385_I	0.582	0.92
283_Y	386_Y	0.581	0.92
81_G	109_F	0.581	0.92
175_D	178_H	0.580	0.92
69_G	94_I	0.579	0.92
286_I	409_F	0.579	0.92
384_F	409_F	0.579	0.92
148_P	153_Y	0.578	0.92
159_V	163_Y	0.578	0.92
80_A	125_F	0.578	0.92
484_A	487_I	0.576	0.91
436_E	440_K	0.576	0.91
77_K	128_N	0.576	0.91
323_I	332_A	0.575	0.91
183_R	475_D	0.572	0.91
343_V	366_I	0.572	0.91
302_L	481_L	0.571	0.91
199_Y	236_I	0.571	0.91
236_I	254_I	0.569	0.91
361_M	369_E	0.569	0.91
105_Q	138_S	0.567	0.91
452_M	457_V	0.566	0.91
346_A	349_Y	0.566	0.91
117_L	142_L	0.565	0.91
187_I	254_I	0.564	0.91
194_L	252_Y	0.564	0.91
315_D	318_P	0.563	0.91
376_E	381_Q	0.563	0.91
49_A	53_L	0.563	0.91
190_M	254_I	0.562	0.90
124_V	133_S	0.562	0.90
361_M	364_G	0.561	0.90
240_L	253_E	0.561	0.90
391_E	394_P	0.560	0.90
257_V	274_I	0.560	0.90
419_A	470_L	0.559	0.90
460_L	464_M	0.558	0.90
431_Q	460_L	0.555	0.90
55_K	60_E	0.555	0.90
76_G	110_K	0.554	0.90
287_M	290_T	0.551	0.90
57_E	61_K	0.550	0.90
353_H	378_T	0.549	0.89
194_L	197_H	0.547	0.89
228_I	495_Q	0.547	0.89
151_D	168_L	0.546	0.89
367_I	370_F	0.546	0.89
287_M	420_N	0.546	0.89
170_L	246_G	0.545	0.89
50_Y	66_T	0.545	0.89
77_K	81_G	0.545	0.89
333_T	374_K	0.545	0.89
341_V	385_I	0.543	0.89
186_I	477_L	0.542	0.89
180_F	243_L	0.542	0.89
145_A	462_Y	0.542	0.89
432_R	452_M	0.542	0.89
211_P	231_Y	0.541	0.89
112_S	116_D	0.540	0.89
242_R	455_D	0.540	0.89
316_L	382_P	0.540	0.89
353_H	374_K	0.539	0.89
209_S	212_G	0.538	0.88
149_L	171_I	0.538	0.88
104_D	108_I	0.536	0.88
399_N	430_D	0.535	0.88
321_K	324_H	0.535	0.88
263_V	495_Q	0.535	0.88
268_N	491_L	0.534	0.88
223_H	226_L	0.534	0.88
284_K	340_E	0.533	0.88
57_E	131_E	0.533	0.88
456_F	460_L	0.533	0.88
148_P	151_D	0.533	0.88
297_I	477_L	0.532	0.88
287_M	291_E	0.532	0.88
421_A	470_L	0.531	0.88
283_Y	423_T	0.530	0.88
185_K	189_A	0.529	0.88
330_K	356_E	0.528	0.88
195_D	198_G	0.528	0.88
246_G	465_P	0.528	0.88
284_K	386_Y	0.528	0.88
100_S	105_Q	0.526	0.87
393_S	396_A	0.526	0.87
287_M	409_F	0.526	0.87
55_K	128_N	0.525	0.87
365_H	441_E	0.524	0.87
63_I	123_K	0.524	0.87
458_E	462_Y	0.524	0.87
209_S	228_I	0.523	0.87
439_L	451_L	0.522	0.87
99_D	135_K	0.521	0.87
116_D	145_A	0.520	0.87
386_Y	399_N	0.520	0.87
56_E	61_K	0.519	0.87
95_Y	133_S	0.518	0.87
157_K	161_Q	0.517	0.86
181_I	248_L	0.517	0.86
238_L	456_F	0.516	0.86
344_E	402_D	0.515	0.86
170_L	247_G	0.514	0.86
237_E	424_E	0.513	0.86
286_I	421_A	0.511	0.86
208_H	213_G	0.511	0.86
193_Y	297_I	0.511	0.86
364_G	372_E	0.510	0.86
245_V	456_F	0.510	0.86
183_R	272_T	0.509	0.86
220_I	224_N	0.508	0.86
397_K	430_D	0.508	0.86
403_P	430_D	0.508	0.86
363_V	404_R	0.507	0.85
92_I	132_L	0.507	0.85
383_T	411_L	0.507	0.85
116_D	143_T	0.507	0.85
278_E	286_I	0.507	0.85
70_R	247_G	0.506	0.85
450_H	454_E	0.505	0.85
96_V	100_S	0.505	0.85
179_T	489_D	0.504	0.85
249_E	279_A	0.504	0.85
168_L	462_Y	0.504	0.85
203_E	475_D	0.504	0.85
151_D	157_K	0.502	0.85
341_V	346_A	0.502	0.85
364_G	371_F	0.502	0.85
74_K	113_D	0.501	0.85
371_F	412_F	0.500	0.85
149_L	161_Q	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ex5A	2	0.9639	100	0.103	Contact Map
4pg3A	2	0.9419	100	0.112	Contact Map
4ycuA	3	0.98	100	0.116	Contact Map
4up7A	2	0.986	100	0.116	Contact Map
3a74A	4	0.9699	100	0.133	Contact Map
1e1oA	2	0.9659	100	0.134	Contact Map
3i7fA	2	0.8898	100	0.225	Contact Map
1l0wA	2	0.8637	100	0.236	Contact Map
1eovA	2	0.9058	100	0.236	Contact Map
1c0aA	1	0.8637	100	0.241	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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