GREMLIN Database
FTSH - ATP-dependent zinc metalloprotease FtsH
UniProt: P37476 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 637 (587)
Sequences: 4696 (2601)
Seq/√Len: 107.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
576_R580_E5.6991.00
570_Q574_E5.1681.00
337_E356_K4.0161.00
559_R563_E3.9191.00
548_Q551_Y3.7521.00
43_N48_K3.7141.00
488_I576_R3.5601.00
337_E341_K3.5421.00
519_K552_E3.4641.00
475_I564_C3.4231.00
344_A374_L3.4161.00
386_K393_D3.3971.00
330_R366_S3.3931.00
347_K389_I3.1981.00
580_E584_Q3.1911.00
178_E186_F3.1581.00
344_A355_L3.1411.00
433_V571_I3.1281.00
247_E251_K3.1171.00
569_K573_T3.0741.00
486_E569_K2.9831.00
589_V596_Q2.9721.00
188_E387_K2.9031.00
575_N578_K2.8671.00
433_V575_N2.8461.00
386_K390_D2.8441.00
340_L370_L2.8381.00
487_I572_L2.8091.00
78_T81_P2.7761.00
430_I476_V2.7741.00
511_V560_I2.7261.00
374_L394_I2.7171.00
476_V564_C2.7041.00
519_K556_E2.6731.00
488_I579_L2.6391.00
436_E473_D2.6241.00
478_L502_R2.6201.00
519_K555_Q2.6141.00
488_I580_E2.5911.00
475_I507_A2.5621.00
425_G582_I2.5571.00
486_E565_Y2.5491.00
418_N584_Q2.5481.00
498_N501_Q2.5451.00
566_E570_Q2.5231.00
384_Q396_E2.4101.00
431_G457_M2.3981.00
558_Q562_K2.3921.00
476_V568_A2.3861.00
420_V465_F2.3821.00
390_D393_D2.3541.00
483_V569_K2.3191.00
125_L129_L2.3101.00
503_A561_I2.3021.00
457_M477_G2.2771.00
471_L506_I2.2261.00
184_R188_E2.2131.00
475_I560_I2.2131.00
40_F44_L2.2101.00
192_R371_E2.1911.00
88_Q91_N2.1401.00
469_P491_E2.1201.00
432_L598_K2.1001.00
509_R513_E2.0921.00
494_T514_F2.0911.00
509_R514_F2.0751.00
498_N502_R2.0611.00
36_S39_T2.0491.00
487_I573_T2.0461.00
472_L563_E2.0441.00
351_E388_K2.0071.00
76_F81_P1.9621.00
431_G477_G1.9621.00
223_F252_N1.9561.00
463_R470_E1.9471.00
585_T592_L1.9441.00
444_T591_T1.9251.00
384_Q393_D1.9241.00
338_A341_K1.9221.00
468_K472_L1.9211.00
350_D388_K1.9111.00
476_V567_R1.9071.00
517_S556_E1.9021.00
434_L473_D1.8871.00
472_L564_C1.8791.00
565_Y569_K1.8491.00
419_I489_F1.8341.00
381_A393_D1.8331.00
523_L561_I1.8311.00
185_K385_N1.8041.00
44_L49_V1.7801.00
173_L214_C1.7741.00
93_L96_T1.7611.00
86_A93_L1.7281.00
593_D596_Q1.7201.00
562_K566_E1.7081.00
417_R587_L1.7031.00
40_F52_V1.7021.00
334_I337_E1.6831.00
468_K518_E1.6831.00
114_T118_P1.6801.00
83_G86_A1.6471.00
415_K418_N1.6391.00
47_G96_T1.6331.00
39_T43_N1.6311.00
585_T589_V1.6231.00
452_G465_F1.6191.00
573_T576_R1.6191.00
419_I493_S1.6161.00
473_D567_R1.6151.00
422_Y580_E1.6141.00
350_D390_D1.6141.00
551_Y555_Q1.6121.00
120_V124_I1.6091.00
347_K374_L1.6061.00
119_F123_F1.6061.00
566_E569_K1.6031.00
266_G316_L1.5941.00
344_A394_I1.5931.00
176_V197_V1.5871.00
51_S99_K1.5541.00
123_F127_F1.5501.00
567_R570_Q1.5501.00
42_K46_D1.5451.00
89_I93_L1.5441.00
594_A598_K1.5421.00
471_L494_T1.5261.00
210_L328_V1.5211.00
437_A477_G1.5041.00
584_Q588_K1.5041.00
483_V565_Y1.4931.00
422_Y584_Q1.4921.00
39_T42_K1.4901.00
474_K502_R1.4901.00
392_R396_E1.4811.00
61_Y65_G1.4801.00
124_I128_F1.4781.00
250_K297_N1.4721.00
552_E555_Q1.4661.00
525_F553_I1.4631.00
505_N509_R1.4531.00
93_L98_V1.4491.00
487_I569_K1.4471.00
443_V455_A1.4471.00
578_K581_L1.4401.00
440_V455_A1.4351.00
108_G112_F1.4341.00
487_I576_R1.4231.00
354_N357_S1.4131.00
478_L506_I1.4041.00
418_N489_F1.3991.00
82_E86_A1.3931.00
585_T599_H1.3871.00
451_A454_Y1.3871.00
556_E559_R1.3831.00
415_K461_E1.3801.00
437_A457_M1.3741.00
437_A473_D1.3731.00
489_F493_S1.3611.00
167_D335_G1.3491.00
507_A560_I1.3401.00
91_N95_K1.3330.99
433_V578_K1.3210.99
578_K601_I1.3170.99
429_V582_I1.3100.99
202_P329_D1.3070.99
86_A90_F1.3050.99
581_L603_H1.3040.99
429_V579_L1.2970.99
249_A257_I1.2940.99
548_Q552_E1.2870.99
86_A89_I1.2850.99
117_I120_V1.2800.99
520_L525_F1.2780.99
430_I568_A1.2730.99
140_V143_F1.2730.99
334_I338_A1.2720.99
248_N251_K1.2660.99
93_L97_D1.2650.99
146_S244_D1.2630.99
472_L476_V1.2600.99
116_I120_V1.2500.99
81_P84_K1.2500.99
500_F524_Q1.2470.99
66_Q69_N1.2330.99
472_L567_R1.2320.99
581_L585_T1.2320.99
361_R398_T1.2210.99
441_H458_L1.2200.99
399_D442_K1.2140.99
255_C300_I1.2090.99
158_V212_K1.2050.99
596_Q599_H1.2000.99
438_D474_K1.1970.99
395_D441_H1.1890.99
356_K360_M1.1790.99
118_P121_I1.1690.99
94_K100_V1.1680.99
45_D92_A1.1670.99
214_C303_I1.1620.99
414_K418_N1.1540.98
478_L503_A1.1460.98
79_H82_E1.1430.98
349_L355_L1.1420.98
18_V22_V1.1350.98
92_A95_K1.1320.98
543_Q547_D1.1310.98
344_A349_L1.1280.98
153_E156_K1.1270.98
595_E599_H1.1250.98
478_L498_N1.1160.98
124_I127_F1.1140.98
545_Y550_A1.1140.98
467_T493_S1.1120.98
35_M43_N1.1110.98
90_F100_V1.1110.98
519_K559_R1.1100.98
97_D100_V1.1050.98
119_F125_L1.1040.98
122_I126_F1.1020.98
434_L437_A1.1020.98
96_T100_V1.1020.98
148_A151_Y1.1010.98
126_F130_L1.0950.98
466_Q470_E1.0930.98
380_V393_D1.0860.98
59_G65_G1.0860.98
396_E406_A1.0830.98
582_I600_L1.0820.98
599_H604_G1.0760.98
141_M144_G1.0710.98
271_A536_G1.0700.98
430_I480_G1.0660.97
167_D338_A1.0640.97
484_A579_L1.0640.97
428_T592_L1.0630.97
43_N63_V1.0600.97
483_V573_T1.0600.97
443_V597_I1.0600.97
56_P59_G1.0560.97
502_R505_N1.0550.97
570_Q573_T1.0520.97
76_F79_H1.0490.97
127_F131_N1.0450.97
273_L535_L1.0410.97
88_Q92_A1.0400.97
581_L600_L1.0400.97
19_I23_S1.0390.97
59_G66_Q1.0370.97
599_H603_H1.0340.97
171_Q174_V1.0330.97
90_F93_L1.0290.97
536_G539_F1.0280.97
422_Y488_I1.0270.97
61_Y69_N1.0260.97
268_Q537_R1.0260.97
482_R496_A1.0250.97
92_A96_T1.0210.97
169_E329_D1.0180.97
85_G88_Q1.0170.97
373_L398_T1.0140.97
121_I125_L1.0130.97
470_E474_K1.0100.97
212_K296_A1.0090.96
568_A571_I1.0080.96
21_V25_F1.0040.96
51_S62_E1.0010.96
422_Y583_A1.0000.96
457_M478_L0.9990.96
78_T83_G0.9980.96
419_I465_F0.9970.96
398_T403_A0.9960.96
49_V63_V0.9910.96
423_H427_H0.9910.96
128_F132_Q0.9890.96
13_L20_G0.9880.96
432_L597_I0.9870.96
123_F126_F0.9850.96
581_L584_Q0.9830.96
427_H495_G0.9810.96
365_F373_L0.9800.96
340_L358_I0.9800.96
403_A410_R0.9780.96
337_E355_L0.9770.96
572_L579_L0.9760.96
59_G64_K0.9700.96
444_T454_Y0.9690.96
16_L20_G0.9680.96
118_P122_I0.9680.96
108_G114_T0.9670.96
20_G24_Y0.9640.95
119_F124_I0.9590.95
197_V301_I0.9590.95
430_I571_I0.9590.95
421_A587_L0.9580.95
63_V67_L0.9570.95
564_C567_R0.9570.95
87_D90_F0.9550.95
582_I592_L0.9530.95
585_T596_Q0.9530.95
229_D286_Q0.9470.95
117_I124_I0.9460.95
416_E465_F0.9450.95
440_V443_V0.9450.95
63_V66_Q0.9440.95
86_A96_T0.9440.95
547_D551_Y0.9410.95
189_L382_A0.9380.95
61_Y64_K0.9370.95
357_S391_A0.9330.95
264_A289_V0.9320.95
17_V21_V0.9270.94
35_M40_F0.9270.94
145_K148_A0.9250.94
585_T588_K0.9190.94
552_E558_Q0.9180.94
425_G429_V0.9180.94
475_I503_A0.9170.94
465_F493_S0.9160.94
413_S461_E0.9150.94
231_V279_E0.9140.94
41_I45_D0.9140.94
512_T553_I0.9120.94
414_K417_R0.9110.94
577_D581_L0.9100.94
457_M474_K0.9100.94
80_V84_K0.9030.94
255_C299_G0.9010.93
80_V83_G0.8990.93
598_K602_D0.8950.93
172_E405_P0.8940.93
113_L117_I0.8940.93
473_D476_V0.8910.93
21_V24_Y0.8910.93
61_Y66_Q0.8900.93
501_Q505_N0.8890.93
520_L553_I0.8890.93
418_N422_Y0.8870.93
160_F177_V0.8850.93
476_V571_I0.8820.93
64_K68_K0.8820.93
582_I597_I0.8820.93
361_R399_D0.8810.93
176_V214_C0.8790.93
436_E469_P0.8760.92
500_F523_L0.8760.92
112_F116_I0.8730.92
119_F122_I0.8720.92
107_S111_T0.8710.92
358_I370_L0.8700.92
223_F248_N0.8700.92
87_D93_L0.8670.92
483_V568_A0.8670.92
81_P86_A0.8660.92
527_Q544_N0.8650.92
91_N94_K0.8630.92
474_K506_I0.8620.92
56_P61_Y0.8610.92
193_I301_I0.8560.92
144_G240_S0.8550.92
22_V26_Q0.8540.92
116_I119_F0.8530.91
36_S99_K0.8510.91
425_G583_A0.8500.91
520_L549_I0.8490.91
253_A299_G0.8470.91
267_R311_I0.8460.91
166_A169_E0.8450.91
109_W113_L0.8450.91
45_D94_K0.8440.91
361_R400_R0.8420.91
399_D454_Y0.8410.91
415_K419_I0.8390.91
65_G69_N0.8390.91
56_P63_V0.8340.91
603_H606_L0.8330.90
83_G87_D0.8320.90
560_I564_C0.8320.90
189_L381_A0.8300.90
249_A300_I0.8290.90
184_R187_A0.8290.90
357_S395_D0.8280.90
178_E182_D0.8260.90
520_L552_E0.8260.90
432_L601_I0.8260.90
197_V326_I0.8260.90
62_E66_Q0.8250.90
104_Q107_S0.8250.90
469_P473_D0.8210.90
17_V20_G0.8200.90
252_N255_C0.8200.90
419_I452_G0.8190.90
122_I129_L0.8170.90
209_L367_G0.8150.90
37_Y40_F0.8150.90
141_M145_K0.8150.90
76_F80_V0.8140.89
602_D605_T0.8130.89
332_D335_G0.8120.89
599_H607_P0.8110.89
102_P106_T0.8110.89
108_G111_T0.8110.89
87_D91_N0.8100.89
412_I452_G0.8100.89
555_Q559_R0.8090.89
118_P131_N0.8060.89
423_H495_G0.8060.89
172_E400_R0.8050.89
173_L176_V0.8050.89
49_V52_V0.8030.89
579_L583_A0.8010.89
37_Y41_I0.7990.89
412_I420_V0.7990.89
333_V356_K0.7990.89
479_L503_A0.7940.88
82_E85_G0.7920.88
399_D456_V0.7920.88
63_V69_N0.7900.88
56_P68_K0.7900.88
139_R142_N0.7870.88
428_T443_V0.7860.88
43_N46_D0.7850.88
35_M39_T0.7840.88
511_V557_I0.7830.88
538_D541_N0.7830.88
573_T577_D0.7820.88
547_D550_A0.7810.87
357_S360_M0.7800.87
80_V86_A0.7800.87
570_Q575_N0.7770.87
443_V592_L0.7770.87
121_I124_I0.7770.87
119_F126_F0.7750.87
349_L353_V0.7730.87
119_F129_L0.7730.87
86_A91_N0.7720.87
374_L377_A0.7690.87
244_D248_N0.7680.87
340_L355_L0.7680.87
211_A367_G0.7650.86
418_N587_L0.7650.86
166_A335_G0.7650.86
35_M61_Y0.7630.86
380_V396_E0.7630.86
273_L537_R0.7620.86
118_P128_F0.7610.86
517_S559_R0.7600.86
59_G63_V0.7590.86
86_A98_V0.7590.86
452_G464_Y0.7560.86
578_K600_L0.7560.86
81_P87_D0.7540.86
474_K478_L0.7530.85
146_S149_K0.7520.85
513_E524_Q0.7520.85
580_E583_A0.7480.85
166_A214_C0.7470.85
89_I98_V0.7460.85
442_K591_T0.7460.85
139_R143_F0.7460.85
578_K603_H0.7430.85
179_F193_I0.7390.84
89_I96_T0.7340.84
435_D473_D0.7330.84
595_E598_K0.7330.84
15_L23_S0.7320.84
116_I122_I0.7310.84
507_A557_I0.7310.84
122_I125_L0.7290.84
144_G148_A0.7270.83
433_V601_I0.7270.83
174_V178_E0.7250.83
267_R278_D0.7250.83
90_F94_K0.7240.83
429_V433_V0.7230.83
114_T119_F0.7220.83
449_G454_Y0.7200.83
81_P93_L0.7200.83
41_I49_V0.7200.83
41_I92_A0.7190.83
503_A568_A0.7170.83
500_F503_A0.7170.83
53_S62_E0.7170.83
116_I125_L0.7160.82
107_S110_V0.7140.82
16_L19_I0.7140.82
258_F305_A0.7120.82
94_K97_D0.7110.82
178_E185_K0.7110.82
489_F492_V0.7100.82
475_I561_I0.7090.82
347_K394_I0.7050.82
200_V326_I0.7040.81
471_L514_F0.7040.81
377_A394_I0.7040.81
271_A537_R0.7030.81
65_G68_K0.7020.81
489_F587_L0.7010.81
522_P562_K0.7000.81
518_E559_R0.7000.81
23_S27_T0.6980.81
507_A511_V0.6970.81
419_I491_E0.6960.81
84_K87_D0.6960.81
400_R403_A0.6950.81
489_F583_A0.6940.81
406_A454_Y0.6930.80
77_L81_P0.6930.80
86_A92_A0.6930.80
83_G89_I0.6930.80
277_H280_R0.6920.80
469_P490_G0.6910.80
12_L17_V0.6890.80
15_L25_F0.6890.80
151_Y154_E0.6890.80
37_Y86_A0.6880.80
562_K565_Y0.6880.80
49_V54_V0.6870.80
434_L476_V0.6870.80
103_A106_T0.6860.80
175_E383_R0.6850.80
430_I433_V0.6830.79
102_P107_S0.6800.79
273_L539_F0.6790.79
143_F237_V0.6790.79
13_L16_L0.6790.79
443_V454_Y0.6770.79
602_D606_L0.6770.79
62_E65_G0.6770.79
563_E567_R0.6770.79
552_E556_E0.6750.79
365_F402_I0.6740.79
231_V278_D0.6740.79
51_S101_E0.6730.78
479_L502_R0.6710.78
578_K604_G0.6710.78
563_E566_E0.6700.78
135_G140_V0.6700.78
93_L100_V0.6690.78
33_E39_T0.6690.78
111_T115_T0.6690.78
114_T117_I0.6660.78
95_K98_V0.6660.78
563_E570_Q0.6660.78
231_V280_R0.6630.77
412_I417_R0.6630.77
56_P64_K0.6630.77
78_T86_A0.6620.77
410_R514_F0.6620.77
427_H499_D0.6610.77
418_N580_E0.6610.77
13_L19_I0.6590.77
402_I456_V0.6590.77
14_I23_S0.6580.77
319_P401_V0.6580.77
327_T450_Q0.6570.77
295_S298_E0.6550.77
349_L374_L0.6540.76
159_K209_L0.6530.76
85_G89_I0.6520.76
395_D399_D0.6520.76
420_V464_Y0.6520.76
20_G26_Q0.6510.76
521_G558_Q0.6500.76
142_N148_A0.6490.76
434_L571_I0.6490.76
389_I394_I0.6450.75
479_L568_A0.6440.75
44_L52_V0.6440.75
110_V113_L0.6440.75
197_V303_I0.6420.75
549_I552_E0.6400.75
200_V309_A0.6390.75
118_P126_F0.6390.75
69_N76_F0.6380.75
358_I394_I0.6380.75
543_Q550_A0.6370.75
521_G565_Y0.6370.75
226_S289_V0.6370.75
363_P458_L0.6370.75
189_L592_L0.6360.74
472_L560_I0.6340.74
431_G456_V0.6340.74
50_D64_K0.6330.74
127_F130_L0.6330.74
535_L539_F0.6330.74
497_H500_F0.6330.74
407_K410_R0.6320.74
47_G97_D0.6320.74
500_F522_P0.6310.74
44_L96_T0.6290.74
535_L538_D0.6280.74
358_I395_D0.6270.73
16_L24_Y0.6260.73
272_G275_G0.6260.73
111_T116_I0.6250.73
187_A299_G0.6250.73
58_R64_K0.6250.73
110_V114_T0.6250.73
584_Q587_L0.6240.73
407_K420_V0.6230.73
273_L536_G0.6230.73
548_Q555_Q0.6230.73
14_I18_V0.6220.73
106_T111_T0.6220.73
239_A282_Q0.6220.73
28_S50_D0.6220.73
410_R454_Y0.6220.73
44_L93_L0.6220.73
54_V59_G0.6220.73
93_L99_K0.6220.73
535_L541_N0.6210.73
115_T118_P0.6180.72
179_F294_F0.6180.72
82_E93_L0.6180.72
91_N96_T0.6180.72
16_L25_F0.6180.72
495_G499_D0.6160.72
133_A136_G0.6160.72
146_S150_L0.6150.72
22_V25_F0.6140.72
396_E448_R0.6140.72
430_I440_V0.6130.72
28_S31_K0.6130.72
309_A535_L0.6130.72
60_V63_V0.6130.72
85_G90_F0.6130.72
104_Q109_W0.6120.72
335_G366_S0.6120.72
42_K95_K0.6120.72
61_Y68_K0.6100.71
58_R61_Y0.6100.71
89_I92_A0.6090.71
479_L561_I0.6090.71
466_Q506_I0.6080.71
386_K392_R0.6070.71
594_A597_I0.6060.71
546_S551_Y0.6040.71
325_Q450_Q0.6040.71
61_Y67_L0.6020.70
76_F82_E0.6020.70
471_L509_R0.6020.70
14_I25_F0.6010.70
187_A195_K0.6000.70
333_V337_E0.6000.70
605_T608_E0.6000.70
407_K454_Y0.5990.70
14_I17_V0.5980.70
522_P565_Y0.5980.70
115_T123_F0.5970.70
484_A488_I0.5960.70
34_N39_T0.5950.69
120_V123_F0.5950.69
41_I94_K0.5950.69
233_M237_V0.5950.69
51_S56_P0.5940.69
84_K93_L0.5940.69
589_V603_H0.5940.69
51_S63_V0.5940.69
59_G69_N0.5930.69
537_R544_N0.5930.69
494_T498_N0.5930.69
132_Q135_G0.5920.69
456_V466_Q0.5920.69
507_A561_I0.5910.69
382_A385_N0.5910.69
17_V25_F0.5900.69
250_K298_E0.5890.69
155_K219_G0.5870.68
566_E573_T0.5870.68
82_E89_I0.5870.68
489_F579_L0.5870.68
399_D465_F0.5860.68
47_G98_V0.5860.68
334_I356_K0.5850.68
18_V21_V0.5850.68
198_L325_Q0.5850.68
199_L596_Q0.5850.68
530_G535_L0.5840.68
36_S42_K0.5840.68
36_S53_S0.5830.68
98_V101_E0.5820.68
581_L605_T0.5820.68
438_D459_P0.5820.68
161_K338_A0.5820.68
45_D96_T0.5800.68
14_I22_V0.5800.68
391_A395_D0.5770.67
35_M49_V0.5770.67
79_H83_G0.5760.67
223_F408_K0.5760.67
42_K94_K0.5760.67
505_N527_Q0.5760.67
268_Q314_P0.5750.67
523_L553_I0.5740.67
383_R400_R0.5730.67
83_G90_F0.5730.67
332_D410_R0.5720.66
432_L594_A0.5710.66
417_R446_V0.5710.66
438_D470_E0.5700.66
508_R557_I0.5700.66
427_H496_A0.5690.66
115_T126_F0.5690.66
469_P472_L0.5690.66
253_A300_I0.5690.66
343_H371_E0.5680.66
352_T391_A0.5680.66
181_K219_G0.5670.66
16_L65_G0.5670.66
360_M588_K0.5670.66
24_Y28_S0.5660.66
166_A338_A0.5660.66
523_L557_I0.5650.66
384_Q392_R0.5650.66
150_L248_N0.5650.66
575_N605_T0.5650.66
522_P561_I0.5630.65
77_L84_K0.5620.65
412_I419_I0.5620.65
12_L23_S0.5610.65
85_G91_N0.5600.65
56_P62_E0.5600.65
16_L53_S0.5600.65
12_L20_G0.5590.65
100_V115_T0.5590.65
265_V310_D0.5580.65
83_G93_L0.5580.65
380_V397_A0.5580.65
466_Q514_F0.5580.65
357_S441_H0.5570.64
20_G25_F0.5560.64
600_L603_H0.5560.64
118_P125_L0.5550.64
16_L26_Q0.5550.64
13_L29_N0.5540.64
29_N32_T0.5540.64
188_E348_P0.5540.64
13_L17_V0.5540.64
398_T402_I0.5530.64
231_V239_A0.5520.64
467_T491_E0.5520.64
44_L98_V0.5520.64
152_T155_K0.5520.64
300_I541_N0.5520.64
145_K244_D0.5510.64
52_V98_V0.5510.64
272_G278_D0.5510.64
49_V76_F0.5500.63
200_V325_Q0.5500.63
81_P91_N0.5500.63
471_L560_I0.5490.63
199_L379_L0.5490.63
143_F146_S0.5480.63
330_R450_Q0.5460.63
564_C568_A0.5450.63
169_E407_K0.5450.63
144_G233_M0.5440.63
347_K371_E0.5440.63
441_H456_V0.5430.62
572_L582_I0.5420.62
25_F30_P0.5420.62
536_G541_N0.5420.62
403_A470_E0.5420.62
40_F61_Y0.5410.62
80_V85_G0.5400.62
161_K345_R0.5400.62
35_M392_R0.5400.62
162_D345_R0.5400.62
468_K491_E0.5390.62
328_V514_F0.5390.62
19_I58_R0.5390.62
116_I127_F0.5380.62
81_P90_F0.5380.62
152_T157_R0.5370.62
18_V23_S0.5370.62
277_H537_R0.5370.62
361_R395_D0.5370.62
402_I466_Q0.5370.62
277_H311_I0.5370.62
465_F514_F0.5360.62
144_G244_D0.5360.62
195_K299_G0.5360.62
13_L23_S0.5360.62
415_K436_E0.5360.62
142_N145_K0.5350.61
13_L22_V0.5350.61
77_L83_G0.5350.61
585_T600_L0.5350.61
403_A441_H0.5350.61
58_R62_E0.5330.61
89_I97_D0.5320.61
492_V565_Y0.5320.61
106_T110_V0.5320.61
131_N140_V0.5320.61
423_H499_D0.5310.61
229_D289_V0.5310.61
23_S26_Q0.5300.61
60_V64_K0.5300.61
341_K356_K0.5300.61
12_L15_L0.5290.61
17_V27_T0.5290.61
43_N253_A0.5280.60
538_D544_N0.5280.60
182_D185_K0.5280.60
229_D399_D0.5270.60
14_I29_N0.5270.60
63_V68_K0.5260.60
342_V593_D0.5260.60
77_L85_G0.5240.60
53_S101_E0.5240.60
118_P124_I0.5240.60
333_V360_M0.5230.60
148_A244_D0.5220.59
107_S114_T0.5220.59
126_F493_S0.5200.59
416_E464_Y0.5200.59
90_F96_T0.5200.59
496_A499_D0.5200.59
527_Q542_E0.5190.59
421_A511_V0.5190.59
44_L63_V0.5180.59
543_Q549_I0.5180.59
348_P388_K0.5170.59
327_T535_L0.5170.59
82_E90_F0.5160.59
466_Q474_K0.5150.58
17_V105_E0.5150.58
374_L389_I0.5150.58
446_V592_L0.5150.58
22_V116_I0.5140.58
395_D600_L0.5140.58
508_R544_N0.5130.58
526_G544_N0.5130.58
195_K302_I0.5130.58
115_T122_I0.5130.58
347_K452_G0.5120.58
249_A512_T0.5110.58
352_T390_D0.5110.58
145_K149_K0.5110.58
530_G540_N0.5110.58
380_V405_P0.5100.58
107_S115_T0.5100.58
286_Q290_E0.5100.58
20_G23_S0.5100.58
272_G310_D0.5090.58
309_A328_V0.5080.57
453_G515_G0.5080.57
365_F458_L0.5070.57
398_T454_Y0.5070.57
523_L558_Q0.5070.57
15_L19_I0.5060.57
168_E332_D0.5060.57
342_V371_E0.5060.57
383_R405_P0.5060.57
268_Q271_A0.5060.57
152_T500_F0.5050.57
64_K67_L0.5050.57
270_G277_H0.5050.57
202_P330_R0.5050.57
219_G589_V0.5050.57
379_L383_R0.5050.57
16_L42_K0.5040.57
333_V411_V0.5040.57
40_F78_T0.5040.57
416_E463_R0.5040.57
405_P444_T0.5030.57
508_R512_T0.5020.57
449_G480_G0.5020.57
460_R463_R0.5020.57
226_S278_D0.5020.57
156_K159_K0.5010.56
197_V462_D0.5010.56
330_R335_G0.5010.56
535_L540_N0.5000.56
46_D66_Q0.5000.56
187_A191_A0.5000.56
139_R197_V0.5000.56
159_K162_D0.5000.56
48_K65_G0.5000.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ce7A 3 0.6735 100 0.395 Contact Map
4ww0A 4 0.6766 100 0.405 Contact Map
2dhrA 5 0.719 100 0.439 Contact Map
4cr2J 1 0.5761 100 0.663 Contact Map
4cr2I 1 0.5651 100 0.683 Contact Map
4cr2K 1 0.5918 100 0.696 Contact Map
4cr2L 1 0.5636 100 0.696 Contact Map
4cr2M 1 0.5636 100 0.701 Contact Map
4cr2H 1 0.551 100 0.705 Contact Map
3cf2A 3 0.5243 100 0.708 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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