GREMLIN Database
MFD - Transcription-repair-coupling factor
UniProt: P37474 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 1177 (1106)
Sequences: 2558 (1543)
Seq/√Len: 46.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
852_I861_V8.6751.00
607_S671_D7.1391.00
142_I201_V6.6081.00
721_G726_T6.5451.00
669_I729_I5.9291.00
879_S884_E5.3311.00
735_R740_D5.1641.00
712_R716_N5.0841.00
194_I201_V4.9271.00
837_F909_F4.6801.00
673_K745_D4.5351.00
749_L765_I4.5251.00
639_M668_A4.5151.00
723_K742_V4.4751.00
1031_I1076_V4.4691.00
143_Q220_S4.4541.00
692_I731_I4.3861.00
181_I196_L4.3601.00
722_L730_V4.2991.00
719_I741_V4.2281.00
720_K724_N4.2141.00
704_G718_T4.2081.00
689_Y693_K4.1881.00
309_L315_I4.1241.00
42_T308_I3.9841.00
717_E721_G3.9801.00
721_G730_V3.9751.00
704_G727_V3.8831.00
669_I701_I3.8621.00
862_A885_S3.7621.00
848_K909_F3.6351.00
413_L453_G3.6301.00
389_F399_E3.5971.00
677_L692_I3.5451.00
56_I125_I3.4691.00
54_F307_L3.4591.00
713_K717_E3.3981.00
825_I856_V3.3941.00
593_K597_E3.3921.00
716_N720_K3.3631.00
54_F120_A3.3621.00
132_V295_A3.3341.00
1036_I1045_M3.2201.00
192_V218_L3.1821.00
517_L535_H3.1521.00
143_Q146_H3.1261.00
635_I649_L3.1211.00
520_E533_N3.0931.00
602_K642_E3.0651.00
842_V867_K3.0601.00
67_T119_V3.0141.00
665_A750_I2.9661.00
63_A119_V2.9661.00
148_I196_L2.9521.00
80_L106_V2.9521.00
676_A736_L2.9241.00
721_G727_V2.8881.00
158_V174_F2.8881.00
54_F118_V2.8481.00
153_L181_I2.8421.00
176_I181_I2.8291.00
420_T450_I2.8171.00
826_E858_D2.8031.00
702_N721_G2.7991.00
849_A889_V2.7831.00
703_I729_I2.7561.00
459_F468_V2.7541.00
636_K667_K2.7421.00
70_L119_V2.7331.00
535_H539_S2.7191.00
246_G344_R2.7071.00
584_V993_V2.6241.00
1089_A1097_I2.6101.00
150_P181_I2.5651.00
679_V685_A2.5381.00
630_R634_E2.5341.00
835_V887_V2.5301.00
514_G534_I2.5031.00
403_F467_A2.4941.00
131_P291_Y2.4731.00
713_K716_N2.4441.00
837_F848_K2.4391.00
55_L66_V2.4301.00
818_G851_E2.4171.00
195_E205_R2.4141.00
141_L220_S2.4101.00
120_A297_L2.3741.00
816_Y821_V2.3741.00
825_I887_V2.3611.00
521_T528_H2.3451.00
822_R826_E2.3331.00
149_E152_Q2.3271.00
875_T879_S2.2941.00
839_Y909_F2.2761.00
523_E528_H2.2751.00
585_Q760_T2.2551.00
296_S299_D2.2491.00
432_I448_V2.2341.00
59_N62_Q2.2191.00
154_A164_R2.2171.00
711_T714_E2.1981.00
1062_Q1077_E2.1961.00
348_S351_K2.1851.00
717_E720_K2.1811.00
718_T727_V2.1571.00
408_F465_K2.1511.00
706_L715_A2.1491.00
70_L117_I2.1441.00
665_A675_V2.1401.00
1117_D1120_K2.1321.00
149_E196_L2.1291.00
715_A735_R2.1181.00
816_Y837_F2.1101.00
604_Y673_K2.1091.00
566_Y576_V2.0941.00
604_Y671_D2.0921.00
63_A81_L2.0911.00
604_Y607_S2.0721.00
460_E467_A2.0591.00
1062_Q1080_F2.0530.99
624_E629_L2.0300.99
738_S1001_M2.0280.99
861_V887_V2.0260.99
735_R738_S2.0170.99
599_E643_R2.0120.99
190_N215_I2.0090.99
861_V889_V2.0050.99
764_K767_Q1.9950.99
910_D940_R1.9850.99
238_R242_K1.9810.99
1054_T1057_E1.9800.99
1151_S1154_E1.9760.99
67_T81_L1.9660.99
632_I635_I1.9650.99
836_Y900_I1.9630.99
739_K764_K1.9580.99
997_L1001_M1.9490.99
900_I903_V1.9470.99
163_E173_E1.9410.99
1049_F1080_F1.9370.99
39_S66_V1.9340.99
597_E770_A1.9300.99
147_D199_T1.9160.99
842_V845_I1.9140.99
721_G724_N1.9130.99
208_N211_D1.9130.99
859_A887_V1.9050.99
860_K886_D1.9010.99
706_L730_V1.8990.99
192_V221_I1.8990.99
246_G289_Y1.8910.99
718_T730_V1.8890.99
1048_R1064_E1.8880.99
720_K723_K1.8870.99
470_T473_E1.8790.99
322_L326_E1.8700.99
42_T55_L1.8670.99
908_V937_F1.8590.99
179_G195_E1.8570.99
589_D1009_R1.8500.99
850_D854_M1.8450.99
424_S450_I1.8440.99
706_L719_I1.8220.99
411_V443_L1.8110.99
755_Q917_S1.8110.99
437_T449_Y1.7990.99
613_Q636_K1.7980.99
864_A876_V1.7970.99
132_V136_K1.7970.99
412_F427_L1.7940.99
662_I691_T1.7930.99
662_I692_I1.7710.98
853_S861_V1.7660.98
906_L926_V1.7650.98
147_D198_D1.7610.98
906_L937_F1.7500.98
601_S771_N1.7500.98
118_V301_T1.7490.98
82_Y297_L1.7390.98
302_P305_T1.7370.98
829_L859_A1.7370.98
580_V993_V1.7230.98
849_A863_Y1.7160.98
614_R618_S1.7160.98
233_P277_G1.7150.98
238_R292_E1.7130.98
693_K703_I1.7040.98
1065_M1080_F1.6990.98
176_I196_L1.6950.98
852_I856_V1.6940.98
244_D275_S1.6940.98
852_I887_V1.6830.98
665_A729_I1.6820.98
145_G200_E1.6720.98
848_K851_E1.6720.98
408_F467_A1.6670.98
631_S649_L1.6670.98
704_G710_R1.6650.98
624_E632_I1.6620.98
610_H670_G1.6590.98
296_S347_F1.6570.98
1081_T1160_L1.6560.98
1024_D1098_K1.6560.98
239_A290_F1.6530.98
122_V319_E1.6520.98
533_N541_K1.6510.98
126_R319_E1.6500.98
606_F673_K1.6460.98
722_L727_V1.6430.98
590_D767_Q1.6390.97
141_L222_N1.6310.97
205_R214_S1.6300.97
816_Y909_F1.6230.97
585_Q985_Q1.6150.97
636_K640_E1.6140.97
838_L898_V1.6060.97
609_D613_Q1.5930.97
825_I835_V1.5880.97
606_F671_D1.5870.97
56_I120_A1.5860.97
838_L894_I1.5770.97
179_G198_D1.5690.97
689_Y705_L1.5680.97
849_A853_S1.5650.97
66_V119_V1.5630.97
846_E853_S1.5620.97
585_Q1008_E1.5600.97
318_M322_L1.5520.96
384_R460_E1.5480.96
719_I735_R1.5480.96
1055_I1084_E1.5430.96
676_A743_Y1.5400.96
838_L922_L1.5370.96
1062_Q1072_Y1.5320.96
532_L552_V1.5290.96
906_L935_A1.5290.96
154_A176_I1.5280.96
272_E276_E1.5250.96
852_I889_V1.5220.96
710_R714_E1.5210.96
845_I863_Y1.5210.96
662_I731_I1.5140.96
839_Y844_D1.5140.96
894_I898_V1.5080.96
45_L308_I1.5060.96
538_G567_K1.5030.96
81_L119_V1.5010.96
585_Q984_A1.4990.96
43_S74_L1.4980.96
701_I768_I1.4920.96
513_I566_Y1.4920.96
1031_I1065_M1.4910.96
183_I223_I1.4900.96
701_I729_I1.4890.96
349_F352_I1.4820.95
1045_M1065_M1.4800.95
761_H973_L1.4780.95
980_N985_Q1.4770.95
864_A873_L1.4770.95
196_L201_V1.4670.95
273_R278_Q1.4630.95
295_A299_D1.4530.95
307_L356_Q1.4520.95
361_L366_F1.4480.95
51_K304_N1.4470.95
39_S69_D1.4440.95
120_A124_A1.4370.95
1094_V1097_I1.4310.94
1085_M1097_I1.4310.94
847_R851_E1.4200.94
692_I729_I1.4200.94
567_K570_G1.4190.94
838_L901_P1.4180.94
677_L750_I1.4180.94
133_E137_S1.4170.94
718_T721_G1.4160.94
1034_T1075_E1.4080.94
576_V580_V1.4030.94
612_M670_G1.4020.94
129_L297_L1.4020.94
730_V736_L1.3970.94
82_Y107_I1.3950.94
609_D636_K1.3950.94
131_P300_Y1.3930.94
188_S206_S1.3900.94
192_V206_S1.3900.94
634_E649_L1.3870.93
125_I298_L1.3760.93
188_S192_V1.3710.93
580_V584_V1.3700.93
881_L900_I1.3680.93
824_A907_I1.3650.93
401_E405_K1.3630.93
604_Y639_M1.3450.92
845_I849_A1.3450.92
629_L633_H1.3420.92
240_M271_K1.3370.92
120_A125_I1.3350.92
185_P188_S1.3330.92
144_V217_T1.3330.92
327_A331_T1.3280.92
703_I731_I1.3220.92
612_M615_E1.3130.91
846_E863_Y1.3130.91
1049_F1058_K1.3090.91
363_Y366_F1.3060.91
80_L109_R1.3050.91
606_F773_D1.3040.91
633_H637_K1.3010.91
862_A879_S1.3010.91
58_H62_Q1.3000.91
1061_L1065_M1.2960.91
324_K328_E1.2950.91
1123_E1127_Q1.2940.91
403_F469_I1.2940.91
57_T121_P1.2930.91
589_D593_K1.2900.91
822_R858_D1.2890.91
381_V384_R1.2890.91
1081_T1084_E1.2880.91
749_L774_V1.2880.91
42_T117_I1.2870.91
1058_K1087_V1.2860.91
1004_E1007_E1.2850.91
1074_K1077_E1.2840.90
152_Q156_R1.2820.90
789_S793_V1.2780.90
144_V219_T1.2770.90
704_G714_E1.2700.90
613_Q617_E1.2680.90
710_R715_A1.2610.90
118_V297_L1.2590.90
749_L769_K1.2580.90
314_R317_E1.2540.89
912_D943_K1.2530.89
705_L730_V1.2440.89
587_I984_A1.2390.89
649_L660_V1.2360.89
862_A876_V1.2310.89
153_L196_L1.2250.88
640_E667_K1.2150.88
53_I308_I1.2100.88
856_V887_V1.2070.88
103_R228_E1.2050.87
715_A719_I1.2030.87
169_S173_E1.2010.87
809_V1156_L1.1950.87
52_P305_T1.1920.87
148_I153_L1.1920.87
910_D913_K1.1850.87
821_V852_I1.1840.86
236_K277_G1.1840.86
776_T799_I1.1840.86
879_S885_S1.1790.86
40_V461_L1.1760.86
231_I236_K1.1750.86
856_V859_A1.1740.86
439_S442_A1.1720.86
1118_G1122_F1.1700.86
270_D286_Y1.1690.86
417_K421_Q1.1660.86
78_S109_R1.1660.86
69_D456_Q1.1640.86
704_G721_G1.1620.85
214_S1025_V1.1580.85
431_D1010_K1.1570.85
1052_V1061_L1.1570.85
726_T730_V1.1540.85
818_G854_M1.1500.85
38_R310_D1.1500.85
57_T120_A1.1440.85
1066_I1071_N1.1420.84
67_T79_V1.1410.84
849_A861_V1.1390.84
392_Q396_L1.1370.84
323_Q348_S1.1330.84
425_S429_D1.1330.84
696_F729_I1.1310.84
789_S795_D1.1290.84
502_I516_Y1.1270.84
46_A117_I1.1240.83
510_N548_Q1.1230.83
1061_L1080_F1.1160.83
147_D200_E1.1140.83
56_I298_L1.1090.83
1032_P1076_V1.1090.83
192_V204_I1.1090.83
106_V110_L1.1060.82
839_Y848_K1.1060.82
197_F202_D1.1060.82
821_V938_T1.1040.82
42_T66_V1.1010.82
637_K641_R1.0990.82
171_P184_Y1.0950.82
403_F408_F1.0950.82
404_K410_V1.0930.82
1150_R1154_E1.0920.82
634_E637_K1.0900.82
1052_V1057_E1.0850.81
52_P302_P1.0850.81
1060_E1063_D1.0830.81
33_L37_A1.0830.81
57_T66_V1.0810.81
322_L329_F1.0810.81
749_L772_V1.0800.81
150_P154_A1.0800.81
602_K908_V1.0780.81
955_A968_I1.0780.81
600_A1006_I1.0780.81
1036_I1065_M1.0780.81
387_Q396_L1.0770.81
36_S73_L1.0760.81
1055_I1059_N1.0760.81
505_Y515_K1.0760.81
36_S69_D1.0720.80
351_K355_E1.0690.80
107_I297_L1.0650.80
174_F809_V1.0650.80
153_L183_I1.0640.80
815_E957_K1.0620.80
148_I181_I1.0620.80
902_N931_R1.0610.80
129_L300_Y1.0550.79
574_K578_K1.0530.79
150_P196_L1.0520.79
1049_F1083_A1.0520.79
534_I772_V1.0520.79
128_M351_K1.0510.79
690_E693_K1.0480.79
670_G701_I1.0430.79
375_P378_I1.0410.78
509_I1000_Q1.0400.78
900_I914_M1.0400.78
586_D589_D1.0360.78
85_N89_S1.0340.78
1059_N1062_Q1.0340.78
596_A799_I1.0330.78
609_D667_K1.0330.78
44_A47_N1.0310.78
587_I980_N1.0310.78
973_L978_A1.0290.78
712_R715_A1.0280.78
85_N127_R1.0270.77
923_R1068_R1.0270.77
609_D788_M1.0240.77
190_N206_S1.0220.77
686_Q705_L1.0210.77
597_E601_S1.0210.77
668_A675_V1.0210.77
133_E293_K1.0210.77
593_K1008_E1.0160.77
206_S216_E1.0160.77
168_V207_F1.0160.77
53_I306_L1.0120.76
119_V891_T1.0100.76
1053_A1057_E1.0090.76
413_L451_M1.0080.76
949_A975_I1.0080.76
685_A705_L1.0070.76
662_I703_I1.0070.76
617_E636_K1.0060.76
1003_K1007_E1.0060.76
677_L731_I1.0030.76
1058_K1084_E1.0020.76
419_R475_F1.0020.76
823_E827_R1.0010.76
205_R874_E1.0000.76
1114_A1117_D0.9980.75
908_V922_L0.9950.75
400_M410_V0.9930.75
675_V750_I0.9920.75
142_I194_I0.9920.75
411_V451_M0.9910.75
611_E615_E0.9910.75
308_I361_L0.9880.75
809_V839_Y0.9880.75
82_Y129_L0.9870.75
148_I201_V0.9870.75
727_V730_V0.9850.74
191_P207_F0.9840.74
349_F353_V0.9840.74
714_E717_E0.9820.74
802_P981_L0.9800.74
704_G730_V0.9790.74
169_S655_Y0.9780.74
655_Y802_P0.9760.74
1001_M1004_E0.9750.74
721_G731_I0.9750.74
650_C877_M0.9740.74
1072_Y1076_V0.9720.73
202_D1066_I0.9700.73
595_Y773_D0.9680.73
212_Q1068_R0.9680.73
402_R406_S0.9680.73
807_F932_V0.9660.73
548_Q970_M0.9630.73
702_N726_T0.9580.72
180_I767_Q0.9580.72
320_E350_Q0.9570.72
890_S896_T0.9550.72
396_L469_I0.9550.72
459_F473_E0.9550.72
908_V956_I0.9550.72
760_T764_K0.9520.72
631_S634_E0.9500.72
33_L41_F0.9500.72
814_V820_L0.9500.72
1058_K1080_F0.9480.72
30_L41_F0.9460.71
613_Q667_K0.9460.71
622_Y809_V0.9460.71
234_E237_A0.9450.71
662_I770_A0.9440.71
648_L1001_M0.9430.71
75_E79_V0.9430.71
399_E403_F0.9430.71
619_A698_D0.9430.71
152_Q155_S0.9410.71
849_A852_I0.9400.71
848_K889_V0.9390.71
631_S692_I0.9380.71
90_S974_T0.9370.71
197_F696_F0.9370.71
844_D848_K0.9350.71
1049_F1061_L0.9330.70
410_V467_A0.9320.70
82_Y124_A0.9320.70
606_F639_M0.9310.70
763_E774_V0.9310.70
859_A886_D0.9300.70
816_Y851_E0.9290.70
719_I751_I0.9260.70
412_F423_L0.9230.70
751_I770_A0.9220.69
529_K547_E0.9220.69
140_M153_L0.9220.69
389_F396_L0.9210.69
1154_E1157_D0.9200.69
1097_I1106_L0.9200.69
163_E204_I0.9200.69
1056_E1059_N0.9180.69
809_V906_L0.9180.69
475_F894_I0.9170.69
956_I968_I0.9160.69
111_T136_K0.9160.69
513_I555_Y0.9150.69
102_Q105_D0.9130.69
450_I641_R0.9110.69
396_L474_L0.9100.68
802_P1086_K0.9090.68
1021_T1090_R0.9090.68
579_K991_D0.9080.68
111_T132_V0.9070.68
1023_I1085_M0.9050.68
863_Y876_V0.9050.68
883_G902_N0.9040.68
318_M324_K0.9040.68
108_N224_G0.9040.68
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289_Y702_N0.6070.40
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405_K1156_L0.6050.39
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727_V964_S0.6050.39
129_L789_S0.6040.39
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595_Y604_Y0.6040.39
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318_M328_E0.6030.39
397_A543_Y0.6030.39
636_K1042_K0.6030.39
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432_I761_H0.6020.39
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621_P694_E0.6020.39
280_D283_L0.6020.39
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124_A906_L0.5920.38
28_Q31_A0.5920.38
649_L1063_D0.5920.38
60_L64_Q0.5920.38
514_G536_Y0.5920.38
412_F525_N0.5910.38
425_S736_L0.5910.38
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1011_G1014_A0.5870.38
298_L347_F0.5870.38
104_L975_I0.5870.38
314_R1001_M0.5860.38
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731_I1097_I0.5850.37
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270_D273_R0.5840.37
608_P640_E0.5840.37
603_G606_F0.5830.37
636_K939_Y0.5830.37
30_L45_L0.5830.37
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845_I865_H0.5810.37
835_V859_A0.5810.37
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716_N740_D0.5800.37
234_E293_K0.5800.37
594_L809_V0.5800.37
582_T585_Q0.5790.37
877_M906_L0.5790.37
112_N357_K0.5780.37
313_S316_H0.5780.37
410_V575_R0.5770.37
47_N211_D0.5770.37
790_M809_V0.5770.37
502_I519_I0.5770.37
204_I430_Y0.5760.37
1030_Y1038_D0.5760.37
527_I534_I0.5760.37
511_H813_V0.5760.37
491_A494_I0.5760.37
679_V772_V0.5750.37
709_F728_D0.5750.37
922_L1152_A0.5750.37
124_A384_R0.5750.37
1148_K1157_D0.5750.37
236_K275_S0.5740.36
870_E873_L0.5740.36
441_K637_K0.5740.36
1110_E1114_A0.5730.36
214_S1027_L0.5730.36
392_Q395_V0.5730.36
649_L776_T0.5730.36
715_A740_D0.5730.36
769_K1043_I0.5730.36
350_Q981_L0.5730.36
487_K730_V0.5730.36
422_K962_L0.5730.36
419_R955_A0.5730.36
438_D442_A0.5730.36
829_L993_V0.5720.36
569_G980_N0.5720.36
1029_A1082_V0.5720.36
326_E330_I0.5720.36
581_E1077_E0.5720.36
365_L368_R0.5720.36
1143_I1149_G0.5710.36
1049_F1084_E0.5710.36
567_K602_K0.5710.36
968_I1048_R0.5710.36
1149_G1152_A0.5710.36
570_G1148_K0.5700.36
271_K275_S0.5700.36
509_I864_A0.5700.36
898_V901_P0.5690.36
179_G633_H0.5680.36
567_K1069_F0.5680.36
703_I721_G0.5680.36
703_I941_R0.5670.36
714_E885_S0.5670.36
841_R910_D0.5670.36
64_Q68_D0.5660.36
1147_T1158_T0.5660.36
853_S862_A0.5650.36
635_I660_V0.5650.36
315_I821_V0.5650.36
329_F974_T0.5650.36
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931_R1002_L0.5640.36
939_Y942_D0.5630.35
354_A731_I0.5630.35
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331_T335_E0.5620.35
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1110_E1138_G0.5610.35
201_V913_K0.5610.35
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282_E338_K0.5530.35
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350_Q357_K0.5530.35
550_D1098_K0.5530.35
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332_N335_E0.5520.34
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609_D815_E0.5350.33
525_N537_Q0.5350.33
543_Y836_Y0.5350.33
217_T1071_N0.5350.33
1118_G1121_L0.5350.33
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790_M1156_L0.5340.33
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667_K902_N0.5340.33
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1075_E1089_A0.5330.33
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437_T443_L0.5330.33
686_Q922_L0.5320.33
391_G396_L0.5320.33
94_V284_V0.5320.33
1040_K1044_D0.5320.33
1062_Q1066_I0.5320.33
410_V933_A0.5310.33
150_P176_I0.5310.33
285_K1043_I0.5310.33
605_A644_P0.5310.33
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181_I908_V0.5310.33
707_S836_Y0.5300.33
648_L710_R0.5300.33
933_A956_I0.5300.33
882_E1106_L0.5290.32
73_L79_V0.5290.32
138_S809_V0.5290.32
769_K789_S0.5290.32
89_S974_T0.5290.32
87_L285_K0.5280.32
142_I196_L0.5280.32
385_Q631_S0.5280.32
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1027_L1078_Y0.5280.32
609_D640_E0.5280.32
540_D679_V0.5280.32
149_E854_M0.5270.32
836_Y1075_E0.5270.32
113_G116_P0.5270.32
120_A1088_Y0.5270.32
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612_M796_L0.5270.32
487_K750_I0.5270.32
686_Q999_S0.5270.32
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808_P960_T0.5260.32
1054_T1087_V0.5260.32
610_H667_K0.5260.32
195_E679_V0.5260.32
1116_I1120_K0.5250.32
116_P802_P0.5250.32
842_V876_V0.5250.32
526_G677_L0.5250.32
171_P186_L0.5240.32
183_I584_V0.5240.32
1001_M1036_I0.5240.32
412_F990_I0.5240.32
105_D222_N0.5230.32
814_V938_T0.5230.32
72_S937_F0.5230.32
202_D711_T0.5230.32
933_A1094_V0.5230.32
492_E906_L0.5230.32
543_Y765_I0.5230.32
94_V1042_K0.5220.32
296_S1094_V0.5220.32
929_S1047_K0.5220.32
298_L1054_T0.5220.32
345_L400_M0.5220.32
736_L951_K0.5210.32
141_L144_V0.5210.32
566_Y898_V0.5210.32
181_I706_L0.5210.32
286_Y826_E0.5210.32
195_E796_L0.5200.32
461_L777_L0.5200.32
307_L469_I0.5200.32
1093_R1143_I0.5200.32
177_R1068_R0.5200.32
595_Y648_L0.5200.32
609_D971_R0.5190.32
93_A995_F0.5190.32
39_S55_L0.5190.32
649_L796_L0.5190.32
596_A914_M0.5190.32
1100_D1103_A0.5190.32
27_E1134_L0.5190.32
316_H320_E0.5180.32
226_A1017_E0.5180.32
662_I951_K0.5180.32
878_L882_E0.5180.32
179_G533_N0.5180.32
48_E54_F0.5180.32
655_Y966_F0.5180.32
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345_L966_F0.5170.31
730_V820_L0.5170.31
756_R842_V0.5170.31
181_I618_S0.5170.31
945_L969_A0.5170.31
582_T760_T0.5160.31
91_E123_A0.5160.31
46_A55_L0.5160.31
154_A202_D0.5150.31
188_S221_I0.5150.31
939_Y1042_K0.5150.31
917_S1044_D0.5140.31
142_I789_S0.5140.31
303_D1006_I0.5140.31
472_E1023_I0.5140.31
284_V288_S0.5140.31
891_T913_K0.5130.31
414_G622_Y0.5130.31
151_D176_I0.5130.31
174_F298_L0.5130.31
143_Q215_I0.5130.31
610_H993_V0.5130.31
592_I1005_A0.5120.31
896_T902_N0.5120.31
85_N284_V0.5120.31
513_I743_Y0.5120.31
729_I1063_D0.5110.31
731_I871_N0.5110.31
622_Y634_E0.5110.31
432_I641_R0.5110.31
617_E640_E0.5110.31
95_A284_V0.5110.31
837_F938_T0.5110.31
557_G984_A0.5110.31
353_V896_T0.5100.31
543_Y1038_D0.5100.31
496_S553_Q0.5100.31
85_N94_V0.5100.31
697_Q701_I0.5100.31
450_I614_R0.5100.31
152_Q719_I0.5100.31
547_E737_L0.5100.31
861_V949_A0.5100.31
777_L1001_M0.5090.31
749_L862_A0.5090.31
303_D361_L0.5090.31
968_I1028_D0.5090.31
616_F951_K0.5090.31
448_V852_I0.5090.31
702_N718_T0.5090.31
698_D702_N0.5090.31
280_D597_E0.5080.31
697_Q1031_I0.5080.31
865_H926_V0.5080.31
715_A731_I0.5080.31
631_S737_L0.5080.31
662_I669_I0.5070.31
190_N216_E0.5070.31
527_I883_G0.5070.31
974_T991_D0.5070.31
195_E430_Y0.5060.31
198_D286_Y0.5060.31
565_L632_I0.5060.31
159_E821_V0.5060.31
790_M903_V0.5060.31
604_Y773_D0.5060.31
875_T949_A0.5050.30
454_E459_F0.5050.30
89_S95_A0.5040.30
89_S282_E0.5040.30
668_A773_D0.5040.30
66_V590_D0.5040.30
537_Q778_T0.5040.30
274_L280_D0.5040.30
43_S703_I0.5030.30
320_E349_F0.5030.30
228_E816_Y0.5030.30
100_R844_D0.5030.30
296_S352_I0.5030.30
315_I901_P0.5030.30
70_L599_E0.5030.30
167_M1069_F0.5030.30
548_Q961_E0.5030.30
543_Y697_Q0.5020.30
163_E170_A0.5020.30
52_P113_G0.5020.30
773_D839_Y0.5020.30
789_S837_F0.5010.30
713_K943_K0.5010.30
494_I966_F0.5010.30
157_L199_T0.5010.30
56_I1061_L0.5010.30
578_K581_E0.5010.30
307_L360_L0.5010.30
711_T917_S0.5010.30
603_G756_R0.5010.30
995_F1004_E0.5010.30
52_P116_P0.5000.30
70_L997_L0.5000.30
787_H995_F0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3hjhA 1 0.3738 100 0.793 Contact Map
1gm5A 1 0.5879 100 0.801 Contact Map
2d7dA 2 0.497 100 0.813 Contact Map
1c4oA 1 0.3874 100 0.822 Contact Map
4cbhA 1 0.2838 100 0.875 Contact Map
4q2cA 1 0.6134 100 0.879 Contact Map
4u4cA 1 0.4401 100 0.881 Contact Map
2fwrA 1 0.3067 100 0.884 Contact Map
4w7sA 2 0.3526 100 0.886 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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