DNAC - BACSU - GREMLIN Contacts

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DNAC - Replicative DNA helicase

UniProt:	P37469	Sequences: MTDLLNDRLPPQNIEAEQAVLGAIFLQPSALTLASEVLIPDDFYRMSHQKIYNAMLVLGDRGEPVDLVTVTSELANTDLLEEVGGISYLTDIANSVPTAANIEYYAKIVEEKSILRRLIRTATTIAQDGYTREDEVEDLLSEAEKTIMEVAQRKNTSAFQNIKDVLVQTYDNIEQLHNRKGDITGIPTGFTELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVATKTDESVAIFSLEMGAEQLVMRMLCAEGNINAQNLRTGNLTEEDWGKLTMAMGSLSNSGIYIDDTPGIRVSEIRAKCRRLKQESGLGMILIDYLQLIQGSGRSKDNRQQEVSEISRELKSIARELQVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYDKETENKNIIEIIIAKQRNGPVGTVSLAFVKEYNKFVNLERRFDDAGVPPGA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	454 (433)
Sequences:	3920 (2651)
Seq/√Len:	127.4

ECOLI - DNAB
BACSU - DNAC YORI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
366_G	369_Q	3.924	1.00
42_D	113_S	3.545	1.00
305_C	317_I	3.418	1.00
202_R	354_Q	3.299	1.00
191_T	440_N	3.242	1.00
188_T	200_F	3.184	1.00
124_T	146_T	3.060	1.00
262_N	272_D	2.967	1.00
234_S	315_G	2.932	1.00
377_M	393_V	2.887	1.00
233_E	315_G	2.842	1.00
204_D	246_Q	2.820	1.00
40_P	53_N	2.752	1.00
227_V	316_M	2.630	1.00
219_F	223_I	2.602	1.00
374_R	413_E	2.540	1.00
430_A	441_L	2.511	1.00
400_D	410_N	2.437	1.00
236_A	308_L	2.362	1.00
343_S	389_D	2.291	1.00
160_Q	244_A	2.291	1.00
317_I	355_V	2.270	1.00
396_L	414_I	2.268	1.00
196_M	425_G	2.209	1.00
73_E	76_N	2.199	1.00
168_Q	245_E	2.197	1.00
210_A	396_L	2.173	1.00
187_P	194_D	2.134	1.00
224_A	318_L	2.125	1.00
61_R	73_E	2.067	1.00
234_S	287_G	2.055	1.00
207_I	390_A	2.035	1.00
291_D	304_K	2.016	1.00
305_C	353_L	2.011	1.00
370_R	379_D	2.010	1.00
197_T	392_I	1.995	1.00
411_I	428_S	1.988	1.00
213_S	421_N	1.980	1.00
55_M	65_V	1.976	1.00
298_V	345_E	1.954	1.00
205_L	346_L	1.944	1.00
289_Y	312_S	1.939	1.00
193_L	394_A	1.937	1.00
395_F	417_A	1.915	1.00
408_N	428_S	1.908	1.00
214_V	402_Y	1.903	1.00
335_R	382_E	1.893	1.00
189_G	194_D	1.889	1.00
335_R	338_E	1.885	1.00
208_V	358_I	1.877	1.00
399_D	403_D	1.875	1.00
57_V	77_T	1.864	1.00
301_I	325_I	1.848	1.00
25_F	70_V	1.835	1.00
113_S	117_R	1.835	1.00
37_V	106_A	1.835	1.00
162_I	248_V	1.835	1.00
214_V	401_Y	1.813	1.00
210_A	214_V	1.741	1.00
259_N	262_N	1.740	1.00
432_V	439_V	1.738	1.00
31_L	56_L	1.734	1.00
229_T	286_S	1.698	1.00
57_V	73_E	1.697	1.00
190_F	429_L	1.666	1.00
24_I	31_L	1.657	1.00
186_I	227_V	1.645	1.00
112_K	115_L	1.639	1.00
161_N	164_D	1.637	1.00
225_Q	255_E	1.636	1.00
80_L	84_G	1.632	1.00
228_A	288_I	1.626	1.00
207_I	386_I	1.622	1.00
73_E	77_T	1.613	1.00
419_Q	423_P	1.610	1.00
392_I	419_Q	1.606	1.00
21_L	48_H	1.604	1.00
343_S	359_A	1.602	1.00
122_A	125_I	1.582	1.00
256_G	435_Y	1.582	1.00
271_E	275_K	1.581	1.00
128_D	142_E	1.570	1.00
220_A	318_L	1.567	1.00
54_A	73_E	1.561	1.00
318_L	358_I	1.558	1.00
218_A	250_R	1.554	1.00
411_I	441_L	1.552	1.00
159_F	236_A	1.547	1.00
196_M	416_I	1.533	1.00
252_L	276_L	1.528	1.00
172_N	176_L	1.527	1.00
257_N	435_Y	1.523	1.00
236_A	317_I	1.521	1.00
40_P	56_L	1.521	1.00
171_D	175_Q	1.519	1.00
24_I	55_M	1.516	1.00
208_V	219_F	1.515	1.00
415_I	426_T	1.511	1.00
20_V	38_L	1.504	1.00
135_E	138_D	1.502	1.00
41_D	49_Q	1.497	1.00
340_S	385_S	1.495	1.00
52_Y	56_L	1.488	1.00
72_S	76_N	1.485	1.00
18_Q	88_Y	1.463	1.00
119_I	129_G	1.462	1.00
20_V	109_V	1.461	1.00
51_I	88_Y	1.460	1.00
202_R	315_G	1.456	1.00
174_E	178_N	1.451	1.00
145_K	149_E	1.442	1.00
323_Q	361_S	1.439	1.00
213_S	424_V	1.437	1.00
9_L	12_Q	1.431	1.00
218_A	436_N	1.427	1.00
172_N	245_E	1.411	1.00
192_E	440_N	1.411	1.00
203_N	243_G	1.408	1.00
117_R	120_R	1.405	1.00
11_P	119_I	1.402	1.00
264_R	419_Q	1.396	1.00
42_D	110_E	1.394	1.00
236_A	305_C	1.390	1.00
413_E	426_T	1.383	1.00
234_S	313_G	1.375	1.00
71_T	89_L	1.364	1.00
412_I	438_F	1.358	1.00
224_A	237_I	1.358	1.00
37_V	107_K	1.354	1.00
281_G	285_N	1.342	1.00
45_R	48_H	1.339	1.00
103_E	107_K	1.337	1.00
54_A	70_V	1.334	1.00
46_M	49_Q	1.323	1.00
255_E	282_S	1.321	1.00
316_M	358_I	1.318	1.00
336_Q	340_S	1.318	1.00
397_Y	402_Y	1.309	1.00
192_E	195_R	1.308	1.00
50_K	79_L	1.306	1.00
225_Q	254_A	1.301	1.00
97_P	105_Y	1.299	1.00
16_A	109_V	1.298	1.00
173_I	276_L	1.296	1.00
301_I	319_I	1.295	1.00
122_A	129_G	1.295	1.00
213_S	418_K	1.294	1.00
200_F	316_M	1.291	1.00
259_N	434_E	1.278	1.00
184_T	201_Q	1.277	1.00
122_A	126_A	1.275	1.00
30_A	102_I	1.274	1.00
200_F	223_I	1.270	1.00
253_C	263_L	1.264	1.00
165_V	244_A	1.264	1.00
146_T	149_E	1.255	1.00
419_Q	422_G	1.253	1.00
18_Q	95_S	1.249	1.00
302_R	352_E	1.232	1.00
219_F	414_I	1.231	1.00
204_D	421_N	1.230	1.00
123_T	126_A	1.221	0.99
220_A	360_L	1.217	0.99
23_A	102_I	1.215	0.99
24_I	34_A	1.213	0.99
14_I	45_R	1.212	0.99
110_E	114_I	1.210	0.99
432_V	435_Y	1.210	0.99
394_A	414_I	1.196	0.99
333_D	337_Q	1.196	0.99
169_T	249_M	1.183	0.99
349_I	353_L	1.179	0.99
374_R	426_T	1.178	0.99
201_Q	204_D	1.178	0.99
381_R	388_Q	1.172	0.99
169_T	173_I	1.167	0.99
228_A	235_V	1.165	0.99
305_C	357_V	1.160	0.99
226_N	231_T	1.160	0.99
309_K	354_Q	1.156	0.99
364_S	367_V	1.156	0.99
53_N	57_V	1.155	0.99
34_A	106_A	1.147	0.99
125_I	143_A	1.145	0.99
102_I	106_A	1.144	0.99
258_I	276_L	1.143	0.99
71_T	75_A	1.143	0.99
398_R	402_Y	1.143	0.99
224_A	235_V	1.140	0.99
13_N	72_S	1.135	0.99
48_H	88_Y	1.125	0.99
370_R	376_M	1.123	0.99
430_A	439_V	1.122	0.99
334_N	337_Q	1.115	0.99
432_V	437_K	1.113	0.99
119_I	130_Y	1.111	0.99
203_N	354_Q	1.105	0.99
79_L	82_E	1.098	0.99
43_F	52_Y	1.094	0.99
237_I	288_I	1.093	0.99
18_Q	48_H	1.090	0.99
365_R	387_E	1.088	0.99
16_A	108_I	1.085	0.99
223_I	227_V	1.083	0.99
309_K	314_L	1.082	0.99
221_L	251_M	1.080	0.99
289_Y	308_L	1.075	0.99
187_P	231_T	1.071	0.99
367_V	401_Y	1.067	0.99
381_R	384_G	1.066	0.99
257_N	437_K	1.065	0.99
142_E	146_T	1.050	0.98
322_L	386_I	1.042	0.98
262_N	269_T	1.041	0.98
309_K	313_G	1.040	0.98
296_I	301_I	1.037	0.98
180_K	267_N	1.037	0.98
333_D	336_Q	1.030	0.98
349_I	357_V	1.029	0.98
374_R	415_I	1.029	0.98
211_R	368_E	1.023	0.98
269_T	272_D	1.013	0.98
319_I	346_L	1.008	0.98
108_I	112_K	1.006	0.98
142_E	145_K	1.005	0.98
159_F	308_L	1.004	0.98
364_S	401_Y	1.004	0.98
191_T	195_R	1.002	0.98
22_G	96_V	1.000	0.98
120_R	124_T	0.999	0.98
160_Q	165_V	0.998	0.98
160_Q	164_D	0.991	0.98
169_T	252_L	0.982	0.98
364_S	393_V	0.982	0.98
396_L	412_I	0.980	0.98
253_C	259_N	0.978	0.98
213_S	377_M	0.977	0.97
190_F	222_N	0.975	0.97
175_Q	178_N	0.973	0.97
221_L	237_I	0.970	0.97
34_A	102_I	0.968	0.97
406_T	409_K	0.966	0.97
160_Q	168_Q	0.964	0.97
115_L	139_L	0.960	0.97
373_K	402_Y	0.955	0.97
293_T	296_I	0.954	0.97
217_T	247_L	0.952	0.97
236_A	355_V	0.949	0.97
227_V	233_E	0.945	0.97
272_D	275_K	0.943	0.97
214_V	412_I	0.941	0.97
368_E	373_K	0.938	0.97
219_F	396_L	0.934	0.97
197_T	416_I	0.931	0.97
166_L	280_M	0.930	0.97
86_I	90_T	0.928	0.97
268_L	276_L	0.927	0.97
87_S	91_D	0.925	0.96
193_L	414_I	0.923	0.96
107_K	111_E	0.921	0.96
175_Q	179_R	0.921	0.96
201_Q	264_R	0.920	0.96
256_G	279_A	0.920	0.96
72_S	75_A	0.919	0.96
367_V	373_K	0.915	0.96
121_T	146_T	0.912	0.96
42_D	117_R	0.910	0.96
348_S	351_R	0.908	0.96
67_L	71_T	0.906	0.96
211_R	387_E	0.906	0.96
228_A	286_S	0.901	0.96
80_L	85_G	0.900	0.96
177_H	273_W	0.896	0.96
114_I	140_L	0.896	0.96
232_D	285_N	0.895	0.96
206_I	392_I	0.892	0.96
15_E	18_Q	0.891	0.96
406_T	411_I	0.891	0.96
365_R	384_G	0.890	0.96
21_L	92_I	0.889	0.96
208_V	220_A	0.888	0.96
110_E	113_S	0.886	0.96
336_Q	382_E	0.883	0.95
287_G	315_G	0.883	0.95
205_L	343_S	0.881	0.95
72_S	108_I	0.880	0.95
13_N	112_K	0.875	0.95
31_L	59_G	0.874	0.95
18_Q	91_D	0.873	0.95
71_T	80_L	0.873	0.95
11_P	130_Y	0.872	0.95
343_S	385_S	0.871	0.95
384_G	387_E	0.867	0.95
172_N	175_Q	0.866	0.95
46_M	50_K	0.866	0.95
32_T	59_G	0.864	0.95
51_I	89_L	0.861	0.95
28_P	65_V	0.861	0.95
41_D	117_R	0.860	0.95
305_C	314_L	0.859	0.95
340_S	344_R	0.858	0.95
212_P	387_E	0.858	0.95
31_L	35_S	0.856	0.95
324_L	389_D	0.854	0.95
65_V	69_T	0.852	0.94
165_V	248_V	0.850	0.94
271_E	274_G	0.850	0.94
257_N	439_V	0.849	0.94
399_D	406_T	0.848	0.94
198_A	265_T	0.848	0.94
33_L	103_E	0.847	0.94
240_L	296_I	0.845	0.94
87_S	90_T	0.841	0.94
347_K	391_D	0.838	0.94
315_G	355_V	0.833	0.94
205_L	359_A	0.831	0.94
400_D	406_T	0.831	0.94
57_V	61_R	0.830	0.94
158_A	304_K	0.829	0.94
329_G	332_K	0.826	0.94
168_Q	171_D	0.824	0.93
221_L	247_L	0.822	0.93
11_P	44_Y	0.819	0.93
236_A	314_L	0.818	0.93
38_L	43_F	0.818	0.93
225_Q	251_M	0.817	0.93
28_P	70_V	0.817	0.93
410_N	430_A	0.816	0.93
377_M	417_A	0.812	0.93
66_D	105_Y	0.810	0.93
294_P	352_E	0.809	0.93
224_A	228_A	0.807	0.93
101_N	104_Y	0.802	0.92
124_T	128_D	0.797	0.92
134_D	138_D	0.789	0.92
196_M	419_Q	0.789	0.92
390_A	393_V	0.788	0.92
224_A	288_I	0.788	0.92
377_M	395_F	0.785	0.92
165_V	169_T	0.784	0.92
278_M	282_S	0.777	0.91
144_E	148_M	0.777	0.91
12_Q	44_Y	0.777	0.91
80_L	83_V	0.776	0.91
328_S	341_E	0.774	0.91
27_Q	99_A	0.770	0.91
188_T	194_D	0.769	0.91
200_F	227_V	0.768	0.91
400_D	409_K	0.767	0.91
115_L	129_G	0.767	0.91
400_D	433_K	0.766	0.91
261_Q	265_T	0.766	0.91
385_S	389_D	0.765	0.91
24_I	28_P	0.765	0.91
316_M	356_P	0.765	0.91
346_L	359_A	0.764	0.91
123_T	127_Q	0.764	0.91
121_T	150_V	0.764	0.91
39_I	42_D	0.759	0.90
67_L	90_T	0.759	0.90
141_S	299_S	0.758	0.90
193_L	200_F	0.757	0.90
35_S	59_G	0.756	0.90
218_A	221_L	0.756	0.90
246_Q	421_N	0.755	0.90
209_A	363_L	0.755	0.90
403_D	406_T	0.754	0.90
190_F	219_F	0.753	0.90
66_D	101_N	0.751	0.90
23_A	99_A	0.751	0.90
141_S	145_K	0.751	0.90
212_P	368_E	0.750	0.90
296_I	304_K	0.748	0.90
261_Q	423_P	0.748	0.90
398_R	401_Y	0.747	0.90
251_M	288_I	0.745	0.89
203_N	246_Q	0.744	0.89
217_T	221_L	0.744	0.89
30_A	33_L	0.742	0.89
53_N	79_L	0.739	0.89
238_F	317_I	0.734	0.89
128_D	146_T	0.732	0.89
176_L	249_M	0.729	0.88
26_L	97_P	0.728	0.88
240_L	324_L	0.728	0.88
172_N	249_M	0.727	0.88
193_L	416_I	0.727	0.88
227_V	235_V	0.727	0.88
211_R	365_R	0.726	0.88
212_P	390_A	0.725	0.88
166_L	169_T	0.723	0.88
212_P	384_G	0.723	0.88
63_E	107_K	0.719	0.88
255_E	279_A	0.716	0.88
314_L	353_L	0.716	0.88
16_A	68_V	0.713	0.87
213_S	392_I	0.713	0.87
171_D	174_E	0.712	0.87
59_G	65_V	0.712	0.87
121_T	147_I	0.712	0.87
204_D	419_Q	0.711	0.87
91_D	94_N	0.708	0.87
198_A	201_Q	0.708	0.87
323_Q	382_E	0.707	0.87
368_E	378_S	0.707	0.87
334_N	338_E	0.707	0.87
292_D	351_R	0.706	0.87
225_Q	229_T	0.704	0.87
54_A	77_T	0.703	0.87
67_L	89_L	0.700	0.86
169_T	248_V	0.699	0.86
54_A	57_V	0.698	0.86
235_V	316_M	0.697	0.86
13_N	16_A	0.697	0.86
193_L	197_T	0.694	0.86
138_D	141_S	0.691	0.86
336_Q	385_S	0.691	0.86
413_E	428_S	0.691	0.86
50_K	83_V	0.689	0.85
319_I	359_A	0.689	0.85
296_I	300_E	0.688	0.85
405_E	409_K	0.688	0.85
138_D	142_E	0.684	0.85
414_I	427_V	0.683	0.85
121_T	143_A	0.682	0.85
397_Y	401_Y	0.680	0.85
218_A	431_F	0.680	0.85
260_A	436_N	0.680	0.85
336_Q	351_R	0.677	0.84
14_I	18_Q	0.676	0.84
26_L	99_A	0.675	0.84
401_Y	424_V	0.674	0.84
81_E	84_G	0.674	0.84
101_N	105_Y	0.673	0.84
222_N	254_A	0.671	0.84
309_K	315_G	0.671	0.84
336_Q	364_S	0.668	0.84
58_L	69_T	0.663	0.83
222_N	225_Q	0.662	0.83
372_D	397_Y	0.661	0.83
111_E	135_E	0.661	0.83
216_K	320_D	0.661	0.83
363_L	381_R	0.660	0.83
259_N	272_D	0.658	0.83
242_M	420_R	0.658	0.83
428_S	441_L	0.656	0.83
298_V	325_I	0.656	0.83
223_I	316_M	0.654	0.82
121_T	125_I	0.653	0.82
148_M	152_Q	0.653	0.82
30_A	34_A	0.652	0.82
349_I	352_E	0.652	0.82
56_L	60_D	0.651	0.82
384_G	388_Q	0.650	0.82
50_K	53_N	0.649	0.82
232_D	287_G	0.649	0.82
339_V	383_S	0.648	0.82
19_A	66_D	0.647	0.82
344_R	348_S	0.647	0.82
397_Y	415_I	0.646	0.82
235_V	318_L	0.646	0.82
229_T	255_E	0.645	0.82
51_I	54_A	0.644	0.81
75_A	80_L	0.644	0.81
240_L	381_R	0.643	0.81
220_A	358_I	0.642	0.81
192_E	427_V	0.642	0.81
367_V	370_R	0.640	0.81
200_F	358_I	0.640	0.81
326_Q	341_E	0.639	0.81
58_L	63_E	0.637	0.81
223_I	358_I	0.637	0.81
72_S	112_K	0.636	0.81
414_I	429_L	0.636	0.81
350_A	357_V	0.636	0.81
40_P	49_Q	0.634	0.80
62_G	326_Q	0.632	0.80
319_I	357_V	0.631	0.80
399_D	402_Y	0.630	0.80
57_V	60_D	0.630	0.80
229_T	282_S	0.629	0.80
398_R	412_I	0.627	0.80
124_T	127_Q	0.627	0.80
298_V	327_G	0.624	0.79
23_A	105_Y	0.624	0.79
126_A	129_G	0.623	0.79
214_V	380_I	0.623	0.79
173_I	263_L	0.623	0.79
38_L	52_Y	0.623	0.79
71_T	86_I	0.622	0.79
173_I	176_L	0.621	0.79
124_T	142_E	0.620	0.79
192_E	441_L	0.620	0.79
26_L	96_V	0.620	0.79
97_P	109_V	0.619	0.79
123_T	130_Y	0.618	0.79
369_Q	376_M	0.617	0.79
149_E	152_Q	0.616	0.78
277_T	281_G	0.615	0.78
211_R	388_Q	0.615	0.78
31_L	65_V	0.614	0.78
209_A	380_I	0.611	0.78
309_K	353_L	0.609	0.78
361_S	385_S	0.609	0.78
32_T	310_Q	0.608	0.78
239_S	247_L	0.608	0.78
118_L	122_A	0.608	0.78
305_C	349_I	0.607	0.77
224_A	247_L	0.605	0.77
110_E	153_R	0.605	0.77
380_I	395_F	0.605	0.77
22_G	98_T	0.602	0.77
336_Q	343_S	0.601	0.77
326_Q	344_R	0.601	0.77
74_L	84_G	0.600	0.77
164_D	168_Q	0.599	0.77
339_V	343_S	0.599	0.77
27_Q	30_A	0.594	0.76
25_F	55_M	0.593	0.76
24_I	30_A	0.592	0.76
88_Y	92_I	0.592	0.76
274_G	277_T	0.589	0.75
44_Y	116_R	0.589	0.75
201_Q	419_Q	0.588	0.75
324_L	344_R	0.588	0.75
176_L	266_G	0.587	0.75
262_N	267_N	0.587	0.75
367_V	397_Y	0.584	0.75
144_E	151_A	0.584	0.75
114_I	136_V	0.584	0.75
416_I	419_Q	0.584	0.75
81_E	85_G	0.583	0.75
212_P	388_Q	0.581	0.74
408_N	413_E	0.580	0.74
280_M	284_S	0.578	0.74
104_Y	107_K	0.577	0.74
331_S	334_N	0.577	0.74
185_G	266_G	0.576	0.74
400_D	412_I	0.575	0.74
103_E	106_A	0.575	0.74
170_Y	280_M	0.573	0.73
298_V	346_L	0.573	0.73
165_V	168_Q	0.573	0.73
122_A	147_I	0.573	0.73
324_L	363_L	0.572	0.73
419_Q	427_V	0.567	0.73
205_L	395_F	0.566	0.72
279_A	282_S	0.565	0.72
203_N	351_R	0.565	0.72
53_N	77_T	0.564	0.72
413_E	440_N	0.564	0.72
243_G	246_Q	0.561	0.72
201_Q	421_N	0.561	0.72
241_E	362_Q	0.560	0.72
237_I	318_L	0.559	0.72
385_S	388_Q	0.559	0.72
429_L	440_N	0.558	0.71
115_L	136_V	0.557	0.71
167_V	284_S	0.554	0.71
98_T	126_A	0.553	0.71
39_I	56_L	0.552	0.71
227_V	315_G	0.551	0.70
333_D	338_E	0.550	0.70
326_Q	348_S	0.547	0.70
54_A	74_L	0.547	0.70
20_V	102_I	0.547	0.70
54_A	58_L	0.547	0.70
344_R	389_D	0.547	0.70
55_M	70_V	0.546	0.70
119_I	123_T	0.546	0.70
202_R	356_P	0.545	0.70
74_L	80_L	0.545	0.70
34_A	37_V	0.545	0.70
270_E	275_K	0.545	0.70
206_I	358_I	0.544	0.69
385_S	393_V	0.544	0.69
295_G	326_Q	0.544	0.69
430_A	442_E	0.544	0.69
204_D	213_S	0.543	0.69
197_T	201_Q	0.542	0.69
86_I	91_D	0.541	0.69
207_I	395_F	0.541	0.69
380_I	393_V	0.540	0.69
412_I	433_K	0.538	0.69
165_V	290_I	0.538	0.69
405_E	408_N	0.537	0.69
212_P	380_I	0.537	0.69
314_L	355_V	0.537	0.69
252_L	280_M	0.536	0.68
302_R	349_I	0.535	0.68
345_E	348_S	0.533	0.68
209_A	367_V	0.532	0.68
24_I	65_V	0.531	0.68
111_E	132_R	0.531	0.68
213_S	401_Y	0.529	0.67
118_L	147_I	0.528	0.67
372_D	402_Y	0.528	0.67
274_G	278_M	0.527	0.67
376_M	379_D	0.527	0.67
309_K	312_S	0.527	0.67
158_A	311_E	0.526	0.67
225_Q	286_S	0.526	0.67
128_D	139_L	0.526	0.67
321_Y	339_V	0.525	0.67
212_P	363_L	0.525	0.67
96_V	99_A	0.524	0.67
205_L	347_K	0.524	0.67
50_K	54_A	0.523	0.66
91_D	95_S	0.522	0.66
215_G	320_D	0.522	0.66
380_I	384_G	0.522	0.66
216_K	241_E	0.521	0.66
300_E	417_A	0.520	0.66
419_Q	425_G	0.519	0.66
143_A	147_I	0.519	0.66
66_D	69_T	0.519	0.66
140_L	150_V	0.517	0.66
257_N	432_V	0.517	0.66
363_L	368_E	0.516	0.65
59_G	310_Q	0.515	0.65
171_D	277_T	0.515	0.65
201_Q	213_S	0.514	0.65
336_Q	381_R	0.514	0.65
308_L	312_S	0.514	0.65
404_K	408_N	0.514	0.65
64_P	69_T	0.514	0.65
401_Y	412_I	0.513	0.65
375_P	384_G	0.513	0.65
183_I	187_P	0.512	0.65
62_G	65_V	0.511	0.65
306_R	352_E	0.511	0.65
169_T	172_N	0.511	0.65
19_A	68_V	0.509	0.64
197_T	206_I	0.509	0.64
45_R	63_E	0.509	0.64
172_N	202_R	0.508	0.64
20_V	43_F	0.506	0.64
51_I	92_I	0.506	0.64
34_A	52_Y	0.506	0.64
283_L	288_I	0.506	0.64
317_I	357_V	0.505	0.64
339_V	342_I	0.505	0.64
193_L	427_V	0.503	0.64
293_T	304_K	0.503	0.64
162_I	166_L	0.502	0.63
194_D	223_I	0.501	0.63
323_Q	380_I	0.501	0.63
287_G	312_S	0.500	0.63
364_S	377_M	0.500	0.63
317_I	349_I	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2q6tA	1	0.9317	100	0.205	Contact Map
4nmnA	3	0.9405	100	0.207	Contact Map
3bgwA	3	0.9141	100	0.222	Contact Map
2r6aA	5	0.9251	100	0.229	Contact Map
3bh0A	1	0.6167	100	0.511	Contact Map
4a1fA	2	0.6322	100	0.52	Contact Map
1cr0A	3	0.5154	100	0.591	Contact Map
1q57A	3	0.9075	100	0.597	Contact Map
3io5A	2	0.4361	100	0.687	Contact Map
1nlfA	3	0.5198	100	0.699	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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