GREMLIN Database
SYM - Methionine--tRNA ligase
UniProt: P37465 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 664 (535)
Sequences: 13488 (6817)
Seq/√Len: 294.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_K44_F5.9611.00
182_D186_K3.7161.00
410_A426_T3.6971.00
117_N290_A3.5931.00
113_K116_D3.5731.00
42_K412_E3.5371.00
130_S161_S3.3951.00
186_K190_E3.1981.00
468_R472_V3.1401.00
34_A339_L3.1251.00
62_K65_Q2.9981.00
124_E169_K2.9871.00
176_R179_K2.9571.00
122_L171_E2.8901.00
6_N44_F2.8151.00
265_W288_L2.7851.00
124_E171_E2.7671.00
413_K417_N2.7381.00
189_E206_N2.7251.00
328_R352_P2.6701.00
109_K113_K2.6561.00
112_Q116_D2.6251.00
194_F298_Q2.6201.00
133_D161_S2.5451.00
415_M477_F2.5391.00
130_S158_S2.5391.00
404_A469_I2.5371.00
158_S161_S2.4871.00
409_K413_K2.4521.00
130_S133_D2.4491.00
189_E201_K2.4211.00
39_K42_K2.3631.00
268_D297_K2.3571.00
66_E76_R2.3341.00
82_Q86_K2.3131.00
45_D263_K2.3071.00
132_P163_H2.2871.00
308_K351_T2.2761.00
20_K80_D2.2701.00
186_K189_E2.2681.00
412_E499_W2.2581.00
45_D264_Y2.2011.00
36_A46_V2.1941.00
38_Y42_K2.1891.00
148_N152_E2.1771.00
183_R292_D2.1751.00
189_E210_K2.1731.00
40_R91_S2.1661.00
534_G537_Q2.1511.00
412_E416_E2.1371.00
185_L210_K2.1221.00
113_K117_N2.1021.00
402_S510_D2.0961.00
89_E480_K2.0951.00
419_E422_V2.0581.00
103_H249_T2.0521.00
38_Y412_E2.0491.00
308_K353_E2.0251.00
258_D262_Q2.0041.00
403_V432_S1.9751.00
126_E169_K1.9701.00
474_L482_P1.9591.00
133_D158_S1.9431.00
10_I36_A1.9281.00
371_L467_L1.9101.00
7_T45_D1.9061.00
87_Q327_E1.9041.00
408_V473_L1.9021.00
80_D83_K1.8841.00
198_E201_K1.8741.00
371_L485_M1.8611.00
178_G182_D1.8571.00
364_A478_L1.8531.00
535_K539_S1.8491.00
41_L472_V1.8431.00
132_P161_S1.8411.00
79_A82_Q1.8181.00
324_T327_E1.8161.00
298_Q418_M1.8091.00
228_K232_N1.8081.00
325_L334_L1.7931.00
423_A477_F1.7591.00
252_G255_T1.7551.00
406_E510_D1.7541.00
39_K416_E1.7521.00
400_L466_S1.7461.00
187_Y190_E1.7411.00
506_G509_K1.7341.00
407_T430_L1.7291.00
431_I470_S1.7211.00
498_A501_S1.7111.00
259_E262_Q1.6921.00
183_R186_K1.6911.00
401_T465_E1.6801.00
176_R215_D1.6741.00
187_Y289_M1.6711.00
426_T429_Q1.6691.00
403_V406_E1.6661.00
72_E76_R1.6641.00
414_A426_T1.6181.00
468_R491_I1.6081.00
38_Y416_E1.5991.00
472_V497_K1.5951.00
382_F385_Q1.5951.00
37_R479_T1.5851.00
54_E99_T1.5851.00
32_G271_L1.5811.00
409_K502_I1.5711.00
397_D437_Y1.5631.00
60_Q64_E1.5561.00
185_L205_I1.5521.00
434_T466_S1.5481.00
402_S406_E1.5461.00
323_V327_E1.5451.00
183_R289_M1.5201.00
364_A481_T1.5191.00
414_A422_V1.5191.00
398_H506_G1.5071.00
157_K164_P1.5021.00
105_V255_T1.4941.00
114_L290_A1.4781.00
101_K105_V1.4771.00
119_D180_Y1.4761.00
404_A466_S1.4761.00
408_V469_I1.4751.00
146_E152_E1.4731.00
406_E410_A1.4401.00
143_V159_P1.4311.00
469_I472_V1.4291.00
82_Q97_R1.4221.00
131_I163_H1.4211.00
79_A83_K1.4211.00
404_A408_V1.4201.00
378_I464_A1.4161.00
537_Q540_A1.4121.00
67_N71_Q1.3991.00
405_E408_V1.3971.00
277_V301_A1.3951.00
471_A485_M1.3921.00
196_Q298_Q1.3911.00
128_W167_L1.3751.00
469_I473_L1.3741.00
126_E167_L1.3681.00
324_T328_R1.3651.00
29_T85_W1.3591.00
403_V407_T1.3571.00
110_V291_L1.3541.00
67_N70_P1.3421.00
392_A454_E1.3381.00
442_A445_V1.3341.00
117_N292_D1.3311.00
146_E154_I1.3311.00
520_F524_E1.3221.00
42_K416_E1.3211.00
29_T90_I1.3131.00
415_M423_A1.3071.00
382_F457_R1.2981.00
158_S163_H1.2891.00
321_D324_T1.2881.00
328_R356_V1.2671.00
513_V516_G1.2661.00
52_T82_Q1.2601.00
125_Y174_F1.2571.00
409_K504_A1.2551.00
5_N45_D1.2541.00
206_N210_K1.2491.00
41_L475_Q1.2381.00
119_D179_K1.2381.00
114_L287_M1.2311.00
256_E262_Q1.2281.00
394_T397_D1.2281.00
411_Y423_A1.2271.00
393_V462_H1.2251.00
181_A185_L1.2251.00
536_M539_S1.2241.00
36_A91_S1.2231.00
179_K182_D1.2211.00
83_K87_Q1.2201.00
540_A544_E1.2171.00
353_E356_V1.2161.00
410_A413_K1.2111.00
404_A430_L1.2021.00
68_I76_R1.2001.00
130_S163_H1.1901.00
281_T299_V1.1881.00
411_Y473_L1.1871.00
424_L477_F1.1821.00
512_K528_E1.1781.00
72_E75_D1.1781.00
407_T426_T1.1751.00
120_I218_V1.1741.00
75_D79_A1.1721.00
471_A482_P1.1711.00
231_E234_K1.1701.00
87_Q323_V1.1681.00
541_P544_E1.1661.00
490_G494_E1.1661.00
525_A545_E1.1651.00
408_V412_E1.1651.00
83_K86_K1.1641.00
444_W459_V1.1631.00
28_T302_H1.1601.00
49_L250_A1.1571.00
202_N207_N1.1571.00
474_L478_L1.1561.00
144_D157_K1.1531.00
35_M39_K1.1521.00
94_D102_R1.1521.00
483_E487_E1.1451.00
517_E527_E1.1361.00
456_L460_M1.1351.00
101_K104_K1.1241.00
403_V433_R1.1191.00
76_R80_D1.1111.00
465_E469_I1.1101.00
533_K537_Q1.0991.00
527_E532_I1.0941.00
395_E398_H1.0861.00
76_R79_A1.0801.00
410_A414_A1.0801.00
107_I237_V1.0751.00
458_S462_H1.0711.00
393_V401_T1.0641.00
7_T263_K1.0641.00
8_F269_V1.0621.00
441_T459_V1.0571.00
42_K499_W1.0541.00
8_F35_M1.0541.00
475_Q482_P1.0531.00
121_Y176_R1.0521.00
227_V242_D1.0521.00
131_I166_E1.0511.00
407_T411_Y1.0491.00
175_F218_V1.0491.00
35_M269_V1.0461.00
218_V237_V1.0421.00
147_R157_K1.0361.00
30_V34_A1.0331.00
132_P158_S1.0281.00
394_T455_E1.0281.00
269_V298_Q1.0261.00
294_P297_K1.0251.00
309_D349_V1.0251.00
427_L474_L1.0231.00
336_Y478_L1.0221.00
71_Q75_D1.0201.00
247_Y288_L1.0201.00
62_K66_E1.0191.00
73_Y77_A1.0181.00
78_A82_Q1.0161.00
398_H402_S1.0101.00
370_L434_T1.0081.00
337_Y360_N1.0081.00
133_D163_H1.0061.00
524_E528_E1.0061.00
537_Q541_P1.0041.00
414_A417_N1.0011.00
106_V109_K0.9981.00
26_A88_L0.9931.00
144_D154_I0.9921.00
533_K536_M0.9901.00
200_R301_A0.9891.00
260_L263_K0.9871.00
128_W142_L0.9861.00
367_L471_A0.9841.00
407_T473_L0.9841.00
34_A415_M0.9831.00
42_K501_S0.9831.00
12_T48_Y0.9811.00
21_L25_H0.9781.00
182_D185_L0.9771.00
175_F241_I0.9761.00
221_T235_H0.9761.00
107_I227_V0.9741.00
85_W90_I0.9741.00
393_V458_S0.9731.00
533_K538_G0.9711.00
190_E293_L0.9701.00
535_K540_A0.9621.00
524_E527_E0.9621.00
144_D156_G0.9561.00
521_P524_E0.9561.00
157_K162_G0.9551.00
425_S429_Q0.9531.00
455_E458_S0.9531.00
400_L433_R0.9511.00
448_K455_E0.9511.00
411_Y427_L0.9491.00
478_L481_T0.9491.00
305_L348_G0.9481.00
103_H246_N0.9461.00
247_Y265_W0.9441.00
511_T514_Q0.9421.00
535_K538_G0.9421.00
269_V300_F0.9381.00
519_L522_R0.9371.00
244_L287_M0.9371.00
275_E304_W0.9351.00
8_F39_K0.9341.00
401_T462_H0.9341.00
201_K206_N0.9341.00
405_E409_K0.9321.00
309_D316_K0.9311.00
340_R424_L0.9301.00
439_D442_A0.9281.00
185_L189_E0.9271.00
540_A543_K0.9251.00
105_V108_E0.9211.00
414_A423_A0.9211.00
532_I535_K0.9211.00
336_Y424_L0.9181.00
35_M420_F0.9131.00
272_V281_T0.9121.00
36_A40_R0.9101.00
94_D97_R0.9101.00
185_L209_I0.9091.00
517_E524_E0.9091.00
447_A456_L0.9051.00
367_L485_M0.9041.00
397_D458_S0.9031.00
306_L349_V0.9001.00
121_Y215_D0.8951.00
195_I277_V0.8941.00
510_D514_Q0.8891.00
259_E263_K0.8881.00
506_G510_D0.8871.00
4_E45_D0.8831.00
309_D317_G0.8821.00
516_G520_F0.8821.00
527_E531_Y0.8801.00
111_F237_V0.8761.00
514_Q517_E0.8761.00
183_R187_Y0.8751.00
75_D99_T0.8701.00
403_V514_Q0.8701.00
464_A468_R0.8691.00
68_I71_Q0.8681.00
307_M310_G0.8651.00
529_I538_G0.8641.00
142_L165_V0.8631.00
87_Q326_I0.8621.00
269_V418_M0.8611.00
207_N210_K0.8601.00
447_A450_P0.8601.00
462_H466_S0.8601.00
312_M319_V0.8561.00
400_L430_L0.8561.00
471_A486_F0.8561.00
12_T32_G0.8561.00
307_M319_V0.8551.00
524_E532_I0.8541.00
326_I331_L0.8531.00
150_K154_I0.8511.00
528_E531_Y0.8481.00
366_D431_I0.8471.00
209_I282_I0.8461.00
195_I205_I0.8441.00
519_L524_E0.8441.00
172_S217_A0.8431.00
12_T92_N0.8421.00
411_Y426_T0.8421.00
110_V245_F0.8411.00
484_K487_E0.8381.00
525_A528_E0.8381.00
408_V500_D0.8371.00
77_A80_D0.8371.00
367_L470_S0.8361.00
258_D261_Y0.8361.00
178_G215_D0.8351.00
525_A529_I0.8351.00
23_I319_V0.8351.00
197_P200_R0.8341.00
38_Y415_M0.8331.00
508_L511_T0.8311.00
20_K84_L0.8311.00
83_K323_V0.8301.00
528_E532_I0.8281.00
23_I305_L0.8281.00
52_T97_R0.8271.00
85_W92_N0.8251.00
35_M418_M0.8231.00
48_Y92_N0.8211.00
40_R46_V0.8101.00
118_G176_R0.8101.00
111_F120_I0.8081.00
162_G315_S0.8061.00
69_T72_E0.8041.00
162_G316_K0.8041.00
307_M317_G0.8031.00
12_T29_T0.8031.00
127_G136_F0.8021.00
30_V339_L0.8011.00
538_G542_A0.8011.00
455_E459_V0.8001.00
518_P522_R0.7990.99
410_A422_V0.7990.99
436_K440_E0.7980.99
3_Q6_N0.7970.99
361_Y365_N0.7970.99
108_E112_Q0.7940.99
399_T403_V0.7930.99
405_E503_T0.7910.99
521_P527_E0.7900.99
545_E548_E0.7890.99
406_E507_Q0.7890.99
454_E458_S0.7860.99
41_L498_A0.7860.99
14_I103_H0.7830.99
373_R441_T0.7820.99
187_Y191_N0.7810.99
412_E501_S0.7810.99
393_V398_H0.7780.99
539_S543_K0.7770.99
401_T405_E0.7760.99
284_W296_P0.7750.99
27_Y348_G0.7720.99
180_Y292_D0.7700.99
368_G481_T0.7670.99
520_F523_L0.7670.99
185_L206_N0.7660.99
532_I537_Q0.7620.99
507_Q511_T0.7610.99
31_A271_L0.7580.99
406_E409_K0.7580.99
308_K352_P0.7570.99
34_A477_F0.7570.99
66_E70_P0.7570.99
480_K484_K0.7560.99
538_G541_P0.7560.99
32_G48_Y0.7550.99
529_I533_K0.7540.99
374_T463_L0.7530.99
310_G317_G0.7530.99
466_S469_I0.7530.99
534_G538_G0.7520.99
408_V502_I0.7520.99
535_K541_P0.7510.99
56_G60_Q0.7480.99
136_F217_A0.7480.99
194_F198_E0.7470.99
500_D503_T0.7460.99
517_E521_P0.7450.99
123_D174_F0.7450.99
7_T268_D0.7430.99
533_K540_A0.7430.99
112_Q115_L0.7420.99
107_I242_D0.7410.99
427_L470_S0.7410.99
13_P28_T0.7400.99
370_L438_I0.7400.99
145_I162_G0.7390.99
125_Y217_A0.7390.99
486_F497_K0.7370.99
396_F441_T0.7320.99
531_Y534_G0.7310.99
475_Q486_F0.7310.99
373_R377_M0.7310.99
544_E547_K0.7290.99
201_K205_I0.7260.99
255_T258_D0.7260.99
194_F297_K0.7260.99
106_V252_G0.7240.99
177_M286_I0.7240.99
413_K416_E0.7230.99
405_E504_A0.7230.99
523_L526_E0.7220.99
447_A455_E0.7210.99
6_N39_K0.7190.99
475_Q483_E0.7190.99
524_E529_I0.7190.99
493_D496_L0.7180.99
523_L527_E0.7180.99
372_N375_V0.7170.99
11_T246_N0.7150.99
209_I285_P0.7140.99
47_R264_Y0.7140.99
184_L187_Y0.7130.99
9_Y251_L0.7130.99
546_T549_E0.7100.99
7_T264_Y0.7060.99
352_P356_V0.7060.99
350_F355_F0.7050.99
401_T466_S0.7040.99
537_Q542_A0.6990.99
337_Y354_G0.6980.99
31_A420_F0.6960.99
446_L459_V0.6960.99
404_A462_H0.6940.99
84_L321_D0.6940.99
184_L286_I0.6920.99
289_M294_P0.6910.99
457_R460_M0.6900.99
467_L489_L0.6900.99
524_E531_Y0.6890.99
228_K234_K0.6890.99
9_Y268_D0.6880.98
115_L120_I0.6880.98
484_K488_Q0.6870.98
381_Y385_Q0.6870.98
94_D100_E0.6870.98
534_G540_A0.6860.98
518_P521_P0.6850.98
31_A339_L0.6850.98
497_K500_D0.6840.98
508_L512_K0.6840.98
237_V241_I0.6830.98
252_G256_E0.6820.98
531_Y535_K0.6820.98
539_S542_A0.6810.98
187_Y294_P0.6790.98
133_D162_G0.6790.98
492_T495_S0.6790.98
61_Q166_E0.6790.98
138_T141_Q0.6780.98
274_K304_W0.6770.98
20_K321_D0.6770.98
114_L117_N0.6760.98
510_D513_V0.6760.98
324_T352_P0.6760.98
422_V425_S0.6760.98
411_Y415_M0.6750.98
372_N488_Q0.6740.98
543_K546_T0.6730.98
106_V253_Y0.6720.98
370_L431_I0.6710.98
254_D258_D0.6690.98
375_V379_N0.6680.98
400_L462_H0.6670.98
490_G493_D0.6670.98
110_V241_I0.6650.98
493_D497_K0.6620.98
383_D386_I0.6610.98
481_T484_K0.6610.98
312_M318_N0.6610.98
123_D215_D0.6610.98
400_L437_Y0.6610.98
61_Q65_Q0.6600.98
12_T85_W0.6590.98
526_E530_A0.6590.98
414_A419_E0.6580.98
454_E457_R0.6580.98
405_E502_I0.6570.98
29_T92_N0.6560.98
239_V242_D0.6560.98
475_Q495_S0.6560.98
105_V109_K0.6550.98
357_E360_N0.6540.98
245_F287_M0.6540.98
394_T458_S0.6530.98
402_S405_E0.6530.98
37_R91_S0.6520.98
449_D455_E0.6520.98
527_E538_G0.6510.98
198_E202_N0.6510.98
3_Q263_K0.6510.98
534_G539_S0.6500.98
251_L264_Y0.6490.98
407_T410_A0.6490.98
444_W455_E0.6480.98
316_K319_V0.6480.98
115_L231_E0.6480.98
195_I301_A0.6470.98
401_T507_Q0.6430.98
342_V348_G0.6430.98
65_Q317_G0.6430.98
427_L473_L0.6410.98
293_L297_K0.6390.98
371_L375_V0.6390.98
513_V521_P0.6370.98
397_D462_H0.6360.97
510_D516_G0.6350.97
517_E520_F0.6350.97
137_Y158_S0.6340.97
503_T506_G0.6330.97
380_K460_M0.6330.97
21_L81_I0.6330.97
180_Y290_A0.6320.97
289_M292_D0.6320.97
370_L467_L0.6320.97
542_A545_E0.6310.97
339_L477_F0.6310.97
129_Y134_E0.6300.97
223_F236_V0.6290.97
515_K519_L0.6280.97
369_N373_R0.6280.97
145_I157_K0.6260.97
104_K228_K0.6250.97
381_Y460_M0.6230.97
541_P545_E0.6230.97
354_G357_E0.6220.97
241_I287_M0.6210.97
441_T444_W0.6210.97
512_K516_G0.6210.97
248_L265_W0.6210.97
484_K517_E0.6200.97
66_E73_Y0.6200.97
310_G316_K0.6190.97
60_Q224_D0.6180.97
62_K73_Y0.6170.97
195_I299_V0.6170.97
5_N44_F0.6160.97
39_K46_V0.6160.97
9_Y264_Y0.6140.97
524_E535_K0.6140.97
486_F493_D0.6130.97
93_D96_I0.6120.97
459_V462_H0.6110.97
509_K512_K0.6100.97
106_V249_T0.6090.97
513_V517_E0.6090.97
325_L350_F0.6080.97
446_L456_L0.6080.97
499_W502_I0.6080.97
387_G457_R0.6070.97
371_L374_T0.6070.97
542_A546_T0.6060.97
135_T161_S0.6060.97
282_I286_I0.6050.97
191_N294_P0.6040.97
251_L265_W0.6020.97
312_M320_V0.6010.96
41_L476_P0.6010.96
535_K542_A0.6010.96
468_R486_F0.6010.96
536_M541_P0.6000.96
19_G25_H0.5990.96
130_S137_Y0.5990.96
441_T455_E0.5980.96
516_G524_E0.5980.96
120_I175_F0.5980.96
128_W165_V0.5970.96
185_L204_M0.5970.96
75_D100_E0.5970.96
148_N151_G0.5970.96
422_V426_T0.5970.96
28_T32_G0.5960.96
3_Q45_D0.5960.96
74_V78_A0.5960.96
534_G544_E0.5960.96
177_M180_Y0.5960.96
202_N206_N0.5950.96
306_L347_D0.5950.96
248_L288_L0.5940.96
532_I536_M0.5940.96
433_R436_K0.5940.96
203_E206_N0.5930.96
255_T259_E0.5910.96
461_Y465_E0.5900.96
184_L285_P0.5890.96
256_E261_Y0.5880.96
114_L175_F0.5880.96
263_K266_P0.5880.96
521_P528_E0.5870.96
514_Q518_P0.5870.96
11_T267_A0.5860.96
96_I260_L0.5860.96
265_W293_L0.5860.96
491_I494_E0.5860.96
394_T444_W0.5850.96
8_F418_M0.5850.96
367_L481_T0.5840.96
529_I532_I0.5840.96
466_S470_S0.5820.96
527_E530_A0.5810.96
438_I463_L0.5810.96
154_I157_K0.5800.96
535_K544_E0.5790.96
534_G541_P0.5770.96
137_Y165_V0.5760.96
396_F399_T0.5760.96
47_R260_L0.5750.96
519_L527_E0.5740.95
390_K393_V0.5740.95
399_T433_R0.5740.95
377_M460_M0.5730.95
516_G526_E0.5690.95
397_D444_W0.5680.95
457_R461_Y0.5670.95
519_L523_L0.5670.95
400_L434_T0.5650.95
516_G521_P0.5650.95
173_Y232_N0.5650.95
203_E207_N0.5640.95
62_K315_S0.5640.95
200_R203_E0.5630.95
513_V522_R0.5630.95
515_K520_F0.5630.95
52_T78_A0.5630.95
507_Q510_D0.5610.95
404_A407_T0.5610.95
261_Y265_W0.5610.95
178_G181_A0.5610.95
530_A533_K0.5600.95
325_L352_P0.5580.95
339_L424_L0.5580.95
399_T402_S0.5570.95
514_Q526_E0.5570.95
390_K461_Y0.5570.95
194_F417_N0.5570.95
486_F490_G0.5560.95
310_G349_V0.5560.95
285_P294_P0.5560.95
522_R526_E0.5560.95
320_V350_F0.5540.95
84_L323_V0.5540.95
300_F418_M0.5540.95
145_I155_G0.5540.95
521_P525_A0.5530.94
383_D388_S0.5520.94
177_M213_L0.5520.94
218_V229_V0.5510.94
541_P546_T0.5510.94
499_W503_T0.5500.94
329_Y356_V0.5500.94
517_E523_L0.5490.94
270_H284_W0.5490.94
388_S391_G0.5490.94
343_P421_S0.5490.94
513_V528_E0.5480.94
271_L302_H0.5470.94
247_Y287_M0.5460.94
76_R83_K0.5460.94
161_S164_P0.5440.94
177_M181_A0.5440.94
273_G304_W0.5440.94
184_L282_I0.5430.94
405_E469_I0.5430.94
68_I72_E0.5420.94
536_M540_A0.5420.94
518_P524_E0.5420.94
408_V411_Y0.5410.94
502_I508_L0.5400.94
397_D459_V0.5400.94
382_F386_I0.5380.94
540_A545_E0.5370.94
58_K160_D0.5370.94
430_L473_L0.5360.94
59_I73_Y0.5360.94
224_D228_K0.5350.93
545_E549_E0.5340.93
199_S274_K0.5320.93
544_E549_E0.5310.93
486_F491_I0.5300.93
530_A534_G0.5290.93
119_D176_R0.5270.93
28_T271_L0.5260.93
371_L488_Q0.5260.93
27_Y305_L0.5260.93
50_T92_N0.5250.93
515_K518_P0.5250.93
15_Y29_T0.5250.93
127_G137_Y0.5240.93
319_V322_P0.5230.93
403_V510_D0.5230.93
490_G495_S0.5230.93
273_G302_H0.5230.93
393_V397_D0.5220.93
515_K527_E0.5210.93
41_L499_W0.5210.93
31_A344_F0.5200.92
470_S474_L0.5200.92
278_R282_I0.5200.92
125_Y170_E0.5190.92
149_E153_V0.5190.92
201_K204_M0.5190.92
144_D153_V0.5190.92
147_R150_K0.5170.92
436_K439_D0.5170.92
89_E331_L0.5160.92
375_V488_Q0.5160.92
189_E202_N0.5150.92
525_A547_K0.5140.92
448_K456_L0.5130.92
110_V248_L0.5120.92
143_V162_G0.5120.92
20_K76_R0.5110.92
486_F494_E0.5110.92
104_K108_E0.5110.92
289_M295_L0.5110.92
393_V461_Y0.5100.92
351_T354_G0.5100.92
542_A547_K0.5100.92
516_G523_L0.5100.92
312_M317_G0.5100.92
158_S162_G0.5090.92
191_N201_K0.5090.92
516_G527_E0.5080.92
174_F217_A0.5080.92
532_I538_G0.5080.92
320_V325_L0.5060.91
533_K543_K0.5060.91
509_K531_Y0.5040.91
304_W311_K0.5040.91
511_T515_K0.5030.91
188_Y209_I0.5030.91
398_H401_T0.5030.91
172_S221_T0.5020.91
196_Q200_R0.5020.91
390_K458_S0.5010.91
44_F268_D0.5000.91
512_K515_K0.5000.91
135_T160_D0.5000.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1rqgA 2 0.7997 100 0.195 Contact Map
1gaxA 1 0.9383 100 0.279 Contact Map
1ffyA 1 0.9066 100 0.306 Contact Map
1ileA 1 0.7892 100 0.332 Contact Map
3kflA 1 0.7771 100 0.356 Contact Map
4qreA 1 0.7771 100 0.373 Contact Map
1wz2A 1 0.9172 100 0.377 Contact Map
3ziuA 1 0.7681 100 0.381 Contact Map
3h99A 1 0.7771 100 0.385 Contact Map
2x1lA 1 0.7666 100 0.387 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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