SYS - BACSU - GREMLIN Contacts

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SYS - Serine--tRNA ligase

UniProt:	P37464	Sequences: MLDTKMLRANFQEIKAKLVHKGEDLTDFDKFEALDDRRRELIGKVEELKGKRNEVSQQVAVLKREKKDADHIIKEMREVGEEIKKLDEELRTVEAELDTILLSIPNIPHESVPVGETEDDNVEVRKWGEKPSFAYEPKPHWDIADELGILDFERAAKVTGSRFVFYKGLGARLERALYNFMLDLHVDEYNYTEVIPPYMVNRASMTGTGQLPKFEEDAFKIREEDYFLIPTAEVPITNMHRDEILSGDSLPINYAAFSACFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNQAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIEVWIPSQDTYREISSCSNFEAFQARRANIRFRREAKGKPEHVHTLNGSGLAVGRTVAAILENYQQEDGSVVIPKVLRPYMGNREVMKP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	425 (417)
Sequences:	4327 (2321)
Seq/√Len:	113.7

ECOLI - SYS
BACSU - SYS
HALSA - SYS
SULSO - SYS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
402_Q	408_V	4.569	1.00
240_H	254_Y	4.055	1.00
184_L	309_V	3.848	1.00
123_E	126_K	3.708	1.00
314_E	411_K	3.323	1.00
291_K	294_D	3.273	1.00
37_R	89_E	3.199	1.00
51_K	75_E	3.185	1.00
296_Y	357_E	3.130	1.00
44_K	82_E	3.010	1.00
408_V	414_R	2.969	1.00
138_K	146_E	2.802	1.00
294_D	297_E	2.788	1.00
180_F	312_L	2.746	1.00
165_F	239_M	2.725	1.00
332_A	357_E	2.608	1.00
370_R	377_E	2.589	1.00
143_I	407_V	2.576	1.00
148_G	167_K	2.536	1.00
102_L	206_T	2.531	1.00
114_V	324_T	2.455	1.00
308_R	312_L	2.450	1.00
20_H	114_V	2.434	1.00
125_R	307_E	2.402	1.00
134_A	403_E	2.402	1.00
184_L	312_L	2.399	1.00
30_K	96_E	2.371	1.00
253_N	301_K	2.359	1.00
15_K	29_D	2.329	1.00
125_R	319_V	2.297	1.00
63_K	73_I	2.234	1.00
411_K	414_R	2.208	1.00
62_L	67_K	2.208	1.00
397_L	407_V	2.203	1.00
183_D	416_Y	2.162	1.00
10_N	13_E	2.156	1.00
307_E	311_Q	2.094	1.00
402_Q	406_S	2.083	1.00
298_E	301_K	2.060	1.00
92_T	96_E	2.047	1.00
154_R	243_E	2.044	1.00
109_H	296_Y	2.017	1.00
189_Y	308_R	1.965	1.00
369_R	376_P	1.947	1.00
158_V	165_F	1.937	1.00
288_K	298_E	1.895	1.00
188_E	312_L	1.891	1.00
315_L	339_V	1.888	1.00
202_R	227_F	1.884	1.00
127_W	311_Q	1.877	1.00
230_P	234_V	1.876	1.00
16_A	20_H	1.872	1.00
199_M	221_I	1.857	1.00
204_S	241_R	1.835	1.00
149_I	170_G	1.830	1.00
316_P	399_N	1.828	1.00
194_V	239_M	1.816	1.00
322_M	334_K	1.808	1.00
111_S	333_K	1.795	1.00
58_Q	61_V	1.752	1.00
109_H	357_E	1.735	1.00
33_A	37_R	1.728	1.00
50_G	54_E	1.723	1.00
321_S	333_K	1.721	1.00
198_Y	261_F	1.721	1.00
8_R	35_D	1.698	1.00
16_A	19_V	1.697	1.00
144_A	150_L	1.686	1.00
95_A	99_T	1.665	1.00
17_K	110_E	1.664	1.00
108_P	327_L	1.660	1.00
129_E	132_S	1.653	1.00
246_S	249_S	1.645	1.00
70_D	74_K	1.635	1.00
196_P	235_P	1.632	1.00
331_A	334_K	1.621	1.00
370_R	373_K	1.620	1.00
94_E	98_D	1.613	1.00
30_K	33_A	1.612	1.00
78_E	82_E	1.593	1.00
308_R	311_Q	1.583	1.00
329_F	359_F	1.575	1.00
157_K	243_E	1.567	1.00
48_L	79_V	1.566	1.00
247_G	291_K	1.552	1.00
108_P	324_T	1.544	1.00
295_S	380_H	1.540	1.00
54_E	58_Q	1.526	1.00
253_N	288_K	1.523	1.00
6_M	10_N	1.519	1.00
203_A	241_R	1.506	1.00
42_I	46_E	1.505	1.00
387_L	392_T	1.491	1.00
199_M	226_Y	1.479	1.00
164_V	278_Q	1.474	1.00
17_K	20_H	1.471	1.00
224_E	263_S	1.463	1.00
139_P	142_D	1.463	1.00
174_E	282_N	1.457	1.00
40_E	44_K	1.448	1.00
82_E	85_K	1.447	1.00
49_K	87_D	1.434	1.00
36_D	40_E	1.431	1.00
41_L	90_L	1.424	1.00
202_R	225_D	1.423	1.00
291_K	368_F	1.421	1.00
145_D	153_E	1.420	1.00
154_R	239_M	1.413	1.00
44_K	47_E	1.395	1.00
70_D	73_I	1.389	1.00
236_I	256_A	1.383	1.00
155_A	164_V	1.383	1.00
51_K	54_E	1.380	1.00
202_R	215_E	1.377	1.00
253_N	298_E	1.375	1.00
116_E	120_D	1.352	1.00
11_F	32_E	1.352	1.00
88_E	92_T	1.347	1.00
6_M	13_E	1.345	1.00
289_F	379_V	1.340	1.00
55_V	76_M	1.339	1.00
20_H	324_T	1.336	1.00
167_K	192_T	1.324	1.00
37_R	40_E	1.317	1.00
159_T	226_Y	1.315	1.00
69_A	73_I	1.309	1.00
247_G	371_E	1.304	1.00
74_K	78_E	1.301	1.00
41_L	93_V	1.288	0.99
290_V	298_E	1.287	0.99
240_H	289_F	1.285	0.99
300_E	335_Y	1.272	0.99
215_E	227_F	1.264	0.99
344_Q	348_R	1.254	0.99
35_D	39_R	1.254	0.99
81_E	85_K	1.250	0.99
120_D	323_C	1.242	0.99
314_E	400_Y	1.242	0.99
12_Q	16_A	1.241	0.99
184_L	188_E	1.241	0.99
38_R	42_I	1.235	0.99
295_S	355_N	1.231	0.99
117_T	120_D	1.226	0.99
125_R	303_T	1.224	0.99
304_N	311_Q	1.220	0.99
80_G	84_K	1.217	0.99
296_Y	332_A	1.214	0.99
130_K	316_P	1.211	0.99
400_Y	409_I	1.211	0.99
85_K	89_E	1.210	0.99
139_P	343_S	1.186	0.99
88_E	91_R	1.186	0.99
319_V	337_I	1.186	0.99
61_V	65_E	1.185	0.99
292_P	368_F	1.185	0.99
17_K	108_P	1.183	0.99
47_E	51_K	1.181	0.99
311_Q	317_Y	1.179	0.99
276_I	394_A	1.178	0.99
169_L	420_R	1.176	0.99
184_L	308_R	1.173	0.99
27_D	30_K	1.166	0.99
201_N	204_S	1.163	0.99
6_M	14_I	1.157	0.99
178_Y	257_F	1.157	0.99
366_I	379_V	1.149	0.99
302_L	353_C	1.144	0.99
75_E	78_E	1.144	0.99
126_K	130_K	1.142	0.99
77_R	80_G	1.141	0.99
236_I	356_F	1.141	0.99
311_Q	319_V	1.140	0.99
58_Q	62_L	1.140	0.99
302_L	356_F	1.131	0.99
41_L	86_L	1.130	0.99
89_E	92_T	1.123	0.99
125_R	311_Q	1.121	0.98
288_K	301_K	1.121	0.98
353_C	384_G	1.118	0.98
409_I	414_R	1.114	0.98
184_L	189_Y	1.114	0.98
111_S	296_Y	1.112	0.98
99_T	103_S	1.106	0.98
61_V	64_R	1.097	0.98
68_D	71_H	1.091	0.98
84_K	87_D	1.089	0.98
331_A	356_F	1.085	0.98
15_K	28_F	1.085	0.98
8_R	39_R	1.078	0.98
71_H	75_E	1.066	0.98
207_G	364_A	1.062	0.98
62_L	72_I	1.061	0.98
249_S	252_I	1.057	0.98
181_M	309_V	1.053	0.98
321_S	327_L	1.050	0.98
91_R	95_A	1.049	0.98
34_L	93_V	1.047	0.98
244_I	367_R	1.042	0.98
142_D	145_D	1.041	0.98
220_K	227_F	1.038	0.98
194_V	236_I	1.038	0.98
417_M	420_R	1.036	0.97
361_A	381_T	1.035	0.97
133_F	137_P	1.033	0.97
172_R	183_D	1.027	0.97
303_T	319_V	1.022	0.97
109_H	112_V	1.021	0.97
2_L	7_L	1.021	0.97
7_L	10_N	1.019	0.97
296_Y	300_E	1.018	0.97
300_E	303_T	1.009	0.97
365_N	378_H	1.008	0.97
78_E	81_E	1.006	0.97
5_K	9_A	1.006	0.97
341_I	394_A	1.006	0.97
180_F	412_V	1.003	0.97
71_H	74_K	1.001	0.97
30_K	100_I	0.999	0.97
396_I	400_Y	0.999	0.97
288_K	305_Q	0.999	0.97
341_I	348_R	0.997	0.97
84_K	88_E	0.993	0.97
31_F	100_I	0.993	0.97
205_M	218_A	0.989	0.97
13_E	16_A	0.981	0.97
211_L	218_A	0.981	0.97
368_F	377_E	0.977	0.96
45_V	83_I	0.974	0.96
56_S	76_M	0.971	0.96
303_T	337_I	0.970	0.96
237_T	287_V	0.968	0.96
138_K	142_D	0.967	0.96
93_V	97_L	0.966	0.96
195_I	282_N	0.964	0.96
43_G	47_E	0.959	0.96
182_L	186_V	0.959	0.96
244_I	376_P	0.958	0.96
13_E	17_K	0.957	0.96
312_L	412_V	0.955	0.96
55_V	58_Q	0.954	0.96
48_L	82_E	0.951	0.96
135_Y	403_E	0.947	0.96
370_R	374_G	0.947	0.96
7_L	31_F	0.947	0.96
37_R	96_E	0.944	0.96
17_K	107_I	0.944	0.96
242_D	365_N	0.940	0.96
37_R	93_V	0.939	0.96
33_A	36_D	0.933	0.95
220_K	225_D	0.930	0.95
314_E	408_V	0.929	0.95
297_E	301_K	0.928	0.95
57_Q	60_A	0.923	0.95
31_F	104_I	0.921	0.95
198_Y	259_A	0.919	0.95
155_A	159_T	0.914	0.95
253_N	305_Q	0.913	0.95
304_N	307_E	0.908	0.95
52_R	80_G	0.905	0.95
169_L	419_N	0.904	0.94
213_K	217_D	0.899	0.94
128_G	131_P	0.893	0.94
409_I	417_M	0.891	0.94
96_E	99_T	0.889	0.94
189_Y	305_Q	0.888	0.94
159_T	201_N	0.888	0.94
118_E	320_M	0.880	0.94
185_H	386_G	0.880	0.94
202_R	206_T	0.877	0.94
117_T	325_G	0.877	0.94
314_E	412_V	0.869	0.93
2_L	14_I	0.868	0.93
221_I	226_Y	0.867	0.93
131_P	408_V	0.867	0.93
240_H	252_I	0.866	0.93
11_F	28_F	0.866	0.93
307_E	317_Y	0.863	0.93
46_E	49_K	0.860	0.93
123_E	318_R	0.847	0.92
112_V	321_S	0.844	0.92
76_M	79_V	0.842	0.92
373_K	377_E	0.841	0.92
2_L	6_M	0.841	0.92
41_L	89_E	0.839	0.92
45_V	87_D	0.838	0.92
304_N	308_R	0.837	0.92
247_G	250_L	0.837	0.92
244_I	369_R	0.837	0.92
291_K	370_R	0.833	0.92
100_I	103_S	0.831	0.92
247_G	370_R	0.829	0.92
87_D	91_R	0.829	0.92
191_Y	288_K	0.828	0.91
169_L	417_M	0.826	0.91
183_D	415_P	0.822	0.91
299_L	335_Y	0.816	0.91
63_K	69_A	0.814	0.91
236_I	254_Y	0.813	0.91
198_Y	282_N	0.813	0.91
124_V	335_Y	0.807	0.90
343_S	394_A	0.806	0.90
46_E	90_L	0.806	0.90
34_L	96_E	0.804	0.90
56_S	60_A	0.803	0.90
188_E	308_R	0.801	0.90
209_G	330_T	0.800	0.90
121_N	323_C	0.798	0.90
400_Y	412_V	0.798	0.90
22_G	116_E	0.797	0.90
178_Y	389_V	0.795	0.90
240_H	245_L	0.790	0.89
21_K	328_G	0.789	0.89
355_N	380_H	0.789	0.89
414_R	420_R	0.788	0.89
343_S	346_T	0.788	0.89
57_Q	61_V	0.786	0.89
174_E	195_I	0.784	0.89
159_T	204_S	0.782	0.89
198_Y	280_Q	0.782	0.89
124_V	321_S	0.775	0.89
60_A	73_I	0.774	0.88
62_L	65_E	0.772	0.88
154_R	165_F	0.772	0.88
309_V	387_L	0.772	0.88
116_E	323_C	0.770	0.88
259_A	282_N	0.769	0.88
246_S	369_R	0.768	0.88
98_D	102_L	0.762	0.88
219_F	263_S	0.761	0.88
45_V	49_K	0.758	0.87
131_P	316_P	0.753	0.87
31_F	97_L	0.753	0.87
204_S	238_N	0.751	0.87
76_M	80_G	0.751	0.87
46_E	50_G	0.749	0.87
36_D	39_R	0.745	0.87
44_K	86_L	0.740	0.86
276_I	348_R	0.740	0.86
191_Y	305_Q	0.734	0.86
139_P	394_A	0.733	0.86
239_M	254_Y	0.733	0.86
45_V	90_L	0.732	0.86
176_A	417_M	0.729	0.85
160_G	226_Y	0.729	0.85
149_I	397_L	0.729	0.85
4_T	101_L	0.728	0.85
162_R	350_I	0.726	0.85
198_Y	229_I	0.725	0.85
286_L	302_L	0.724	0.85
41_L	44_K	0.723	0.85
122_V	321_S	0.720	0.85
185_H	255_A	0.720	0.85
292_P	377_E	0.719	0.85
244_I	365_N	0.718	0.84
148_G	168_G	0.718	0.84
150_L	164_V	0.717	0.84
166_Y	393_V	0.717	0.84
30_K	34_L	0.714	0.84
155_A	165_F	0.712	0.84
27_D	100_I	0.712	0.84
371_E	374_G	0.711	0.84
147_L	407_V	0.711	0.84
19_V	25_L	0.710	0.84
167_K	194_V	0.710	0.84
296_Y	355_N	0.708	0.84
42_I	94_E	0.706	0.83
55_V	72_I	0.706	0.83
172_R	418_G	0.703	0.83
144_A	147_L	0.703	0.83
93_V	96_E	0.701	0.83
143_I	401_Q	0.696	0.83
149_I	167_K	0.696	0.83
303_T	353_C	0.695	0.82
210_Q	238_N	0.694	0.82
60_A	77_R	0.693	0.82
49_K	83_I	0.693	0.82
95_A	98_D	0.693	0.82
112_V	327_L	0.693	0.82
144_A	397_L	0.691	0.82
162_R	271_D	0.688	0.82
322_M	331_A	0.688	0.82
55_V	75_E	0.684	0.81
73_I	77_R	0.682	0.81
215_E	220_K	0.681	0.81
77_R	81_E	0.681	0.81
29_D	33_A	0.681	0.81
7_L	14_I	0.680	0.81
149_I	169_L	0.679	0.81
409_I	420_R	0.678	0.81
211_L	215_E	0.678	0.81
237_T	356_F	0.674	0.81
327_L	334_K	0.674	0.81
12_Q	15_K	0.673	0.80
245_L	249_S	0.672	0.80
166_Y	282_N	0.672	0.80
185_H	286_L	0.671	0.80
159_T	221_I	0.671	0.80
34_L	97_L	0.666	0.80
243_E	249_S	0.666	0.80
13_E	110_E	0.664	0.80
324_T	327_L	0.663	0.79
159_T	200_V	0.663	0.79
51_K	55_V	0.662	0.79
240_H	366_I	0.662	0.79
218_A	230_P	0.659	0.79
293_E	370_R	0.659	0.79
232_A	235_P	0.657	0.79
124_V	303_T	0.657	0.79
89_E	93_V	0.653	0.78
191_Y	286_L	0.652	0.78
90_L	93_V	0.652	0.78
19_V	24_D	0.650	0.78
58_Q	72_I	0.649	0.78
408_V	411_K	0.648	0.78
60_A	69_A	0.645	0.78
52_R	83_I	0.645	0.78
158_V	204_S	0.644	0.77
66_K	69_A	0.643	0.77
38_R	97_L	0.642	0.77
245_L	379_V	0.642	0.77
409_I	419_N	0.641	0.77
200_V	235_P	0.640	0.77
137_P	343_S	0.640	0.77
150_L	166_Y	0.639	0.77
37_R	41_L	0.638	0.77
232_A	256_A	0.637	0.77
75_E	82_E	0.636	0.77
400_Y	411_K	0.635	0.76
175_R	193_E	0.635	0.76
218_A	234_V	0.634	0.76
232_A	255_A	0.634	0.76
96_E	100_I	0.630	0.76
257_F	282_N	0.630	0.76
38_R	93_V	0.630	0.76
208_T	237_T	0.626	0.75
86_L	89_E	0.626	0.75
289_F	366_I	0.626	0.75
74_K	77_R	0.626	0.75
69_A	72_I	0.626	0.75
168_G	192_T	0.626	0.75
208_T	287_V	0.625	0.75
38_R	94_E	0.624	0.75
199_M	228_L	0.623	0.75
28_F	31_F	0.623	0.75
339_V	395_A	0.623	0.75
45_V	86_L	0.622	0.75
58_Q	68_D	0.620	0.75
194_V	254_Y	0.620	0.75
147_L	170_G	0.619	0.75
302_L	382_L	0.619	0.75
296_Y	299_L	0.618	0.75
180_F	184_L	0.618	0.75
115_G	325_G	0.618	0.75
275_L	394_A	0.618	0.75
252_I	255_A	0.615	0.74
370_R	375_K	0.615	0.74
134_A	137_P	0.614	0.74
299_L	353_C	0.614	0.74
15_K	19_V	0.614	0.74
7_L	32_E	0.614	0.74
195_I	259_A	0.613	0.74
48_L	83_I	0.613	0.74
169_L	172_R	0.613	0.74
299_L	303_T	0.612	0.74
52_R	79_V	0.612	0.74
182_L	255_A	0.611	0.74
127_W	317_Y	0.610	0.74
81_E	84_K	0.608	0.73
300_E	333_K	0.606	0.73
287_V	356_F	0.605	0.73
59_V	76_M	0.604	0.73
195_I	198_Y	0.603	0.73
137_P	401_Q	0.603	0.73
141_W	273_R	0.601	0.72
358_A	380_H	0.600	0.72
72_I	75_E	0.599	0.72
62_L	68_D	0.599	0.72
278_Q	393_V	0.598	0.72
85_K	88_E	0.596	0.72
63_K	70_D	0.596	0.72
221_I	224_E	0.595	0.72
396_I	412_V	0.595	0.72
6_M	11_F	0.595	0.72
91_R	94_E	0.594	0.72
401_Q	405_G	0.594	0.72
179_N	257_F	0.594	0.72
116_E	119_D	0.593	0.71
347_Y	392_T	0.592	0.71
271_D	348_R	0.592	0.71
309_V	312_L	0.592	0.71
152_F	275_L	0.590	0.71
66_K	70_D	0.589	0.71
220_K	223_E	0.587	0.71
215_E	218_A	0.587	0.71
174_E	389_V	0.586	0.71
83_I	87_D	0.586	0.71
82_E	86_L	0.585	0.70
138_K	143_I	0.585	0.70
15_K	25_L	0.585	0.70
396_I	409_I	0.585	0.70
368_F	379_V	0.584	0.70
157_K	242_D	0.584	0.70
98_D	206_T	0.583	0.70
35_D	101_L	0.581	0.70
54_E	57_Q	0.580	0.70
201_N	226_Y	0.580	0.70
158_V	239_M	0.579	0.70
330_T	334_K	0.578	0.70
6_M	9_A	0.578	0.70
247_G	374_G	0.578	0.70
164_V	275_L	0.578	0.70
288_K	302_L	0.577	0.69
221_I	263_S	0.576	0.69
21_K	108_P	0.576	0.69
219_F	226_Y	0.574	0.69
263_S	267_S	0.574	0.69
112_V	324_T	0.574	0.69
42_I	45_V	0.574	0.69
215_E	222_R	0.573	0.69
306_A	337_I	0.570	0.69
159_T	199_M	0.569	0.68
118_E	348_R	0.569	0.68
200_V	229_I	0.568	0.68
52_R	56_S	0.568	0.68
176_A	419_N	0.567	0.68
309_V	386_G	0.567	0.68
306_A	351_S	0.567	0.68
333_K	355_N	0.566	0.68
238_N	241_R	0.566	0.68
24_D	27_D	0.565	0.68
29_D	32_E	0.564	0.68
63_K	66_K	0.563	0.68
301_K	305_Q	0.562	0.67
350_I	392_T	0.562	0.67
218_A	227_F	0.559	0.67
341_I	346_T	0.559	0.67
44_K	48_L	0.559	0.67
245_L	252_I	0.557	0.67
141_W	152_F	0.556	0.67
162_R	348_R	0.556	0.67
143_I	146_E	0.556	0.67
267_S	270_R	0.556	0.67
109_H	332_A	0.556	0.67
151_D	154_R	0.555	0.66
14_I	107_I	0.554	0.66
351_S	384_G	0.554	0.66
291_K	297_E	0.550	0.66
343_S	348_R	0.549	0.66
135_Y	401_Q	0.549	0.66
136_E	142_D	0.549	0.66
237_T	381_T	0.548	0.65
370_R	376_P	0.546	0.65
144_A	149_I	0.546	0.65
415_P	418_G	0.544	0.65
236_I	255_A	0.543	0.65
240_H	243_E	0.543	0.65
348_R	390_G	0.543	0.65
7_L	11_F	0.542	0.65
20_H	108_P	0.542	0.65
330_T	356_F	0.541	0.65
185_H	189_Y	0.540	0.64
174_E	390_G	0.540	0.64
60_A	64_R	0.538	0.64
41_L	45_V	0.538	0.64
221_I	225_D	0.538	0.64
47_E	50_G	0.538	0.64
392_T	396_I	0.538	0.64
21_K	324_T	0.537	0.64
268_A	272_T	0.537	0.64
252_I	289_F	0.537	0.64
133_F	136_E	0.537	0.64
248_D	371_E	0.536	0.64
38_R	90_L	0.536	0.64
223_E	263_S	0.536	0.64
131_P	314_E	0.534	0.64
25_L	28_F	0.534	0.64
131_P	402_Q	0.533	0.63
165_F	196_P	0.533	0.63
200_V	205_M	0.532	0.63
218_A	258_S	0.531	0.63
166_Y	195_I	0.530	0.63
92_T	95_A	0.530	0.63
316_P	347_Y	0.529	0.63
44_K	89_E	0.528	0.63
43_G	46_E	0.527	0.63
179_N	183_D	0.527	0.63
182_L	193_E	0.526	0.62
59_V	69_A	0.525	0.62
185_H	309_V	0.524	0.62
121_N	325_G	0.523	0.62
321_S	337_I	0.523	0.62
389_V	392_T	0.522	0.62
90_L	94_E	0.522	0.62
62_L	71_H	0.521	0.62
276_I	344_Q	0.520	0.61
3_D	362_R	0.520	0.61
40_E	43_G	0.520	0.61
25_L	104_I	0.519	0.61
111_S	321_S	0.519	0.61
278_Q	394_A	0.518	0.61
11_F	15_K	0.518	0.61
303_T	335_Y	0.518	0.61
229_I	235_P	0.518	0.61
358_A	362_R	0.517	0.61
111_S	300_E	0.516	0.61
240_H	379_V	0.515	0.61
186_V	255_A	0.515	0.61
270_R	320_M	0.513	0.60
155_A	163_F	0.512	0.60
68_D	73_I	0.511	0.60
208_T	234_V	0.510	0.60
60_A	63_K	0.510	0.60
63_K	68_D	0.510	0.60
230_P	385_S	0.508	0.60
414_R	417_M	0.508	0.60
178_Y	282_N	0.507	0.60
341_I	350_I	0.507	0.60
156_A	160_G	0.506	0.59
126_K	347_Y	0.506	0.59
286_L	305_Q	0.505	0.59
190_N	253_N	0.505	0.59
231_T	383_N	0.504	0.59
181_M	385_S	0.503	0.59
66_K	73_I	0.502	0.59
109_H	355_N	0.502	0.59
238_N	287_V	0.500	0.59

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2dq0A	2	0.9976	100	0.231	Contact Map
1sesA	2	0.9812	100	0.234	Contact Map
1wleA	2	0.9882	100	0.247	Contact Map
2dq3A	2	0.9953	100	0.247	Contact Map
3lssA	2	0.9906	100	0.251	Contact Map
3vbbA	2	0.9882	100	0.265	Contact Map
3qneA	2	0.9741	100	0.273	Contact Map
3errA	2	0.9812	100	0.361	Contact Map
2cjaA	2	0.9294	100	0.535	Contact Map
3w3sA	2	0.9035	100	0.597	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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