ILVB - BACSU - GREMLIN Contacts

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ILVB - Acetolactate synthase large subunit

UniProt:	P37251	Sequences: MGTNVQVDSASAECTQTMSGALMLIESLKKEKVEMIFGYPGGAVLPIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMIDSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFHIATTGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAKKPVILAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMALHECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGDSKIVLQELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTKGEAIVATDVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVAVVGDGGFQMTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQPDFVKLSEAYGIKGIRISSEAEAKEKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGLHEMVGVKP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	574 (537)
Sequences:	14245 (9064)
Seq/√Len:	391.2

ECOLI - ILVB ILVG ILVI OXC GCL POXB MEND
BACSU - ILVB ILVX IOLD MEND YDAP
HALSA - MEND
SULSO - Q7LXT8 Q97ZB3 Q97UP3 Q97U16 Q980V7 Q97V62 Q97XR3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
512_K	515_E	4.909	1.00
386_Y	531_K	3.771	1.00
480_N	547_D	3.682	1.00
68_I	98_G	3.527	1.00
242_E	262_H	3.467	1.00
522_I	536_E	3.419	1.00
236_E	340_Q	3.280	1.00
34_E	80_K	3.111	1.00
526_S	529_E	3.096	1.00
523_R	549_R	2.976	1.00
208_R	345_Q	2.948	1.00
390_F	535_E	2.815	1.00
236_E	336_K	2.746	1.00
333_G	338_V	2.649	1.00
77_V	443_E	2.645	1.00
224_A	237_L	2.610	1.00
522_I	544_V	2.573	1.00
520_K	542_E	2.566	1.00
261_D	415_Q	2.564	1.00
386_Y	389_Q	2.525	1.00
35_M	57_V	2.460	1.00
525_S	529_E	2.422	1.00
210_L	312_A	2.348	1.00
522_I	533_K	2.348	1.00
290_I	335_S	2.326	1.00
436_A	450_A	2.313	1.00
284_C	287_L	2.230	1.00
509_D	512_K	2.197	1.00
523_R	547_D	2.169	1.00
314_I	338_V	2.155	1.00
86_A	95_L	2.153	1.00
520_K	536_E	2.152	1.00
389_Q	531_K	2.133	1.00
81_P	163_T	2.126	1.00
22_L	50_K	2.117	1.00
289_S	292_A	2.082	1.00
443_E	446_A	2.068	1.00
61_P	67_A	2.047	1.00
99_L	111_V	2.034	1.00
29_K	54_S	2.026	1.00
213_A	310_K	2.024	1.00
458_Q	517_Y	2.016	1.00
133_G	136_M	1.992	1.00
513_L	516_A	1.987	1.00
214_V	288_I	1.962	1.00
110_V	159_F	1.961	1.00
213_A	286_L	1.960	1.00
93_T	97_T	1.955	1.00
511_V	521_G	1.947	1.00
213_A	329_I	1.939	1.00
222_I	241_A	1.937	1.00
113_T	171_L	1.909	1.00
243_Q	343_I	1.892	1.00
524_I	533_K	1.877	1.00
154_I	172_I	1.867	1.00
26_E	30_K	1.866	1.00
392_K	395_A	1.843	1.00
388_H	413_P	1.828	1.00
535_E	539_T	1.821	1.00
81_P	110_V	1.805	1.00
204_Y	341_E	1.798	1.00
243_Q	347_G	1.798	1.00
457_F	461_L	1.782	1.00
440_Q	473_P	1.780	1.00
22_L	53_N	1.777	1.00
212_E	216_S	1.773	1.00
241_A	248_V	1.772	1.00
520_K	544_V	1.771	1.00
209_K	212_E	1.764	1.00
468_R	519_I	1.755	1.00
478_I	545_V	1.754	1.00
239_N	243_Q	1.752	1.00
222_I	288_I	1.743	1.00
529_E	532_E	1.742	1.00
531_K	535_E	1.740	1.00
72_E	76_R	1.730	1.00
130_D	133_G	1.728	1.00
18_M	26_E	1.722	1.00
238_K	242_E	1.712	1.00
203_N	206_Q	1.699	1.00
29_K	55_G	1.697	1.00
537_A	546_I	1.674	1.00
396_I	439_A	1.664	1.00
222_I	246_I	1.642	1.00
525_S	549_R	1.631	1.00
385_E	389_Q	1.629	1.00
147_Q	150_D	1.615	1.00
235_E	239_N	1.601	1.00
431_F	435_A	1.582	1.00
515_E	520_K	1.576	1.00
400_D	452_V	1.569	1.00
355_W	359_L	1.564	1.00
290_I	314_I	1.564	1.00
387_I	451_V	1.561	1.00
382_K	527_E	1.549	1.00
38_G	58_H	1.541	1.00
78_S	442_A	1.539	1.00
400_D	456_G	1.538	1.00
139_T	171_L	1.529	1.00
143_Y	172_I	1.523	1.00
283_E	358_Q	1.519	1.00
390_F	531_K	1.514	1.00
440_Q	472_L	1.511	1.00
358_Q	362_W	1.509	1.00
26_E	29_K	1.509	1.00
206_Q	209_K	1.506	1.00
360_A	363_K	1.504	1.00
245_Q	264_L	1.503	1.00
48_Y	58_H	1.502	1.00
421_V	439_A	1.496	1.00
511_V	523_R	1.495	1.00
214_V	286_L	1.489	1.00
248_V	258_F	1.478	1.00
211_V	345_Q	1.472	1.00
419_K	446_A	1.468	1.00
353_S	357_K	1.467	1.00
532_E	536_E	1.458	1.00
321_I	332_V	1.457	1.00
532_E	535_E	1.449	1.00
382_K	386_Y	1.449	1.00
27_S	156_K	1.445	1.00
140_K	168_G	1.444	1.00
217_A	220_P	1.443	1.00
24_L	174_I	1.443	1.00
464_L	519_I	1.437	1.00
148_P	181_I	1.434	1.00
477_V	546_I	1.427	1.00
66_G	463_E	1.426	1.00
467_I	519_I	1.411	1.00
477_V	534_L	1.390	1.00
386_Y	390_F	1.390	1.00
24_L	155_I	1.389	1.00
357_K	361_E	1.382	1.00
211_V	342_L	1.379	1.00
467_I	474_V	1.376	1.00
112_F	174_I	1.372	1.00
395_A	447_T	1.372	1.00
383_L	548_V	1.364	1.00
239_N	343_I	1.360	1.00
392_K	447_T	1.356	1.00
61_P	70_A	1.352	1.00
81_P	159_F	1.352	1.00
99_L	109_L	1.351	1.00
393_G	415_Q	1.350	1.00
118_T	177_D	1.343	1.00
31_E	159_F	1.341	1.00
95_L	111_V	1.340	1.00
286_L	312_A	1.338	1.00
461_L	513_L	1.328	1.00
310_K	328_Q	1.326	1.00
361_E	365_E	1.324	1.00
441_L	472_L	1.321	1.00
240_Y	244_Q	1.318	1.00
35_M	441_L	1.313	1.00
391_T	449_V	1.309	1.00
57_V	470_L	1.307	1.00
449_V	538_L	1.305	1.00
475_K	537_A	1.305	1.00
440_Q	447_T	1.304	1.00
477_V	548_V	1.302	1.00
31_E	156_K	1.299	1.00
217_A	286_L	1.298	1.00
336_K	340_Q	1.298	1.00
110_V	162_A	1.284	1.00
207_I	345_Q	1.281	1.00
360_A	364_E	1.280	1.00
202_P	338_V	1.278	1.00
68_I	95_L	1.273	1.00
221_V	284_C	1.267	1.00
511_V	515_E	1.264	1.00
447_T	538_L	1.258	1.00
92_A	113_T	1.255	1.00
513_L	517_Y	1.253	1.00
473_P	542_E	1.251	1.00
240_Y	339_L	1.250	1.00
240_Y	343_I	1.249	1.00
341_E	344_K	1.243	1.00
450_A	476_V	1.242	1.00
437_I	467_I	1.239	1.00
208_R	212_E	1.227	1.00
145_V	151_L	1.226	1.00
482_A	507_Q	1.223	1.00
512_K	516_A	1.221	1.00
238_K	259_P	1.220	1.00
155_I	172_I	1.220	1.00
290_I	339_L	1.220	1.00
473_P	541_R	1.216	1.00
150_D	153_R	1.215	1.00
378_F	548_V	1.210	1.00
59_I	441_L	1.209	1.00
37_F	74_Y	1.209	1.00
21_A	50_K	1.207	1.00
378_F	383_L	1.204	1.00
279_M	283_E	1.201	1.00
396_I	448_V	1.197	1.00
237_L	339_L	1.197	1.00
322_G	327_T	1.196	1.00
74_Y	442_A	1.195	1.00
530_A	548_V	1.191	1.00
334_D	337_I	1.188	1.00
36_I	51_L	1.184	1.00
209_K	213_A	1.184	1.00
429_M	459_M	1.181	1.00
19_S	22_L	1.176	1.00
153_R	157_E	1.176	1.00
396_I	443_E	1.175	1.00
27_S	155_I	1.171	1.00
143_Y	157_E	1.167	1.00
393_G	416_K	1.164	1.00
96_V	134_I	1.163	1.00
33_V	83_V	1.163	1.00
239_N	242_E	1.162	1.00
514_S	519_I	1.160	1.00
337_I	340_Q	1.158	1.00
20_G	151_L	1.158	1.00
250_H	265_F	1.154	1.00
23_M	183_G	1.150	1.00
143_Y	154_I	1.150	1.00
363_K	367_P	1.149	1.00
34_E	57_V	1.148	1.00
72_E	101_D	1.145	1.00
204_Y	345_Q	1.144	1.00
222_I	240_Y	1.142	1.00
75_A	108_P	1.142	1.00
533_K	546_I	1.141	1.00
175_P	178_V	1.141	1.00
519_I	545_V	1.136	1.00
514_S	545_V	1.133	1.00
236_E	343_I	1.133	1.00
238_K	258_F	1.131	1.00
236_E	239_N	1.130	1.00
100_A	426_L	1.129	1.00
357_K	360_A	1.125	1.00
215_S	349_Q	1.121	1.00
520_K	540_S	1.119	1.00
301_N	304_H	1.116	1.00
211_V	215_S	1.114	1.00
266_L	280_A	1.110	1.00
220_P	285_D	1.106	1.00
465_D	469_E	1.104	1.00
201_E	341_E	1.103	1.00
77_V	439_A	1.101	1.00
514_S	521_G	1.099	1.00
241_A	258_F	1.094	1.00
228_V	237_L	1.094	1.00
239_N	340_Q	1.093	1.00
219_K	283_E	1.089	1.00
72_E	107_L	1.088	1.00
258_F	262_H	1.086	1.00
215_S	347_G	1.085	1.00
145_V	154_I	1.084	1.00
19_S	182_E	1.083	1.00
119_S	177_D	1.081	1.00
255_L	260_A	1.080	1.00
161_I	170_V	1.079	1.00
118_T	181_I	1.078	1.00
35_M	59_I	1.077	1.00
96_V	138_V	1.076	1.00
391_T	397_V	1.074	1.00
394_E	446_A	1.071	1.00
103_M	169_P	1.070	1.00
242_E	264_L	1.067	1.00
222_I	237_L	1.065	1.00
210_L	331_V	1.063	1.00
93_T	134_I	1.062	1.00
50_K	53_N	1.060	1.00
521_G	545_V	1.057	1.00
522_I	546_I	1.057	1.00
361_E	364_E	1.056	1.00
249_A	266_L	1.053	1.00
530_A	534_L	1.052	1.00
66_G	460_T	1.050	1.00
359_L	363_K	1.049	1.00
134_I	138_V	1.048	1.00
210_L	329_I	1.047	1.00
202_P	341_E	1.046	1.00
440_Q	448_V	1.041	1.00
24_L	112_F	1.038	1.00
327_T	330_P	1.034	1.00
221_V	249_A	1.034	1.00
216_S	310_K	1.034	1.00
73_G	77_V	1.034	1.00
241_A	264_L	1.030	1.00
68_I	84_V	1.029	1.00
84_V	95_L	1.029	1.00
238_K	262_H	1.027	1.00
224_A	228_V	1.026	1.00
482_A	549_R	1.025	1.00
475_K	544_V	1.025	1.00
235_E	238_K	1.023	1.00
536_E	539_T	1.023	1.00
25_I	54_S	1.021	1.00
23_M	152_P	1.018	1.00
211_V	346_D	1.012	1.00
337_I	341_E	1.012	1.00
299_T	302_L	1.008	1.00
59_I	470_L	1.007	1.00
139_T	142_S	1.003	1.00
447_T	475_K	1.001	1.00
478_I	510_F	0.998	1.00
397_V	412_Y	0.997	1.00
44_V	47_I	0.996	1.00
359_L	362_W	0.994	1.00
141_H	161_I	0.991	1.00
433_L	457_F	0.991	1.00
540_S	544_V	0.991	1.00
398_A	448_V	0.987	1.00
289_S	294_F	0.984	1.00
163_T	167_P	0.982	1.00
18_M	182_E	0.981	1.00
432_G	450_A	0.981	1.00
524_I	530_A	0.981	1.00
86_A	111_V	0.980	1.00
275_Y	279_M	0.977	1.00
364_E	368_L	0.977	1.00
440_Q	445_D	0.976	1.00
379_K	554_E	0.974	1.00
440_Q	444_K	0.970	1.00
524_I	529_E	0.964	1.00
388_H	412_Y	0.961	1.00
121_I	144_Q	0.959	1.00
537_A	544_V	0.958	1.00
217_A	285_D	0.958	1.00
457_F	478_I	0.957	1.00
99_L	135_T	0.955	1.00
215_S	346_D	0.955	1.00
24_L	47_I	0.954	1.00
416_K	419_K	0.951	1.00
142_S	171_L	0.948	1.00
47_I	174_I	0.947	1.00
236_E	339_L	0.946	1.00
36_I	83_V	0.944	1.00
398_A	450_A	0.944	1.00
511_V	547_D	0.943	1.00
115_Q	173_D	0.940	1.00
464_L	545_V	0.939	1.00
201_E	337_I	0.939	1.00
132_L	142_S	0.938	1.00
22_L	26_E	0.938	1.00
461_L	517_Y	0.936	1.00
141_H	154_I	0.936	1.00
80_K	163_T	0.935	1.00
221_V	281_L	0.932	1.00
68_I	109_L	0.931	1.00
533_K	537_A	0.931	1.00
234_S	238_K	0.930	1.00
221_V	287_L	0.929	1.00
384_I	451_V	0.929	1.00
475_K	538_L	0.922	1.00
216_S	286_L	0.922	1.00
84_V	111_V	0.919	1.00
92_A	135_T	0.916	1.00
464_L	476_V	0.916	1.00
519_I	543_P	0.915	1.00
471_N	541_R	0.915	1.00
356_K	360_A	0.915	1.00
51_L	56_L	0.912	1.00
382_K	530_A	0.911	1.00
239_N	347_G	0.910	1.00
465_D	517_Y	0.909	1.00
479_L	550_V	0.908	1.00
205_L	208_R	0.906	1.00
529_E	533_K	0.900	1.00
76_R	107_L	0.897	1.00
212_E	215_S	0.897	1.00
331_V	338_V	0.897	1.00
475_K	546_I	0.894	1.00
362_W	365_E	0.892	1.00
243_Q	348_K	0.891	1.00
306_A	309_A	0.891	1.00
157_E	161_I	0.891	1.00
457_F	545_V	0.890	1.00
210_L	286_L	0.887	1.00
467_I	476_V	0.886	1.00
383_L	479_L	0.884	1.00
93_T	100_A	0.882	1.00
244_Q	346_D	0.881	1.00
314_I	331_V	0.880	1.00
390_F	534_L	0.879	1.00
515_E	521_G	0.877	1.00
210_L	213_A	0.875	1.00
133_G	137_P	0.874	1.00
240_Y	346_D	0.872	1.00
18_M	23_M	0.872	1.00
354_E	357_K	0.871	1.00
132_L	144_Q	0.871	1.00
438_G	442_A	0.867	1.00
20_G	148_P	0.866	1.00
27_S	31_E	0.864	1.00
408_S	451_V	0.864	1.00
440_Q	542_E	0.863	1.00
363_K	366_Y	0.858	1.00
213_A	312_A	0.857	1.00
162_A	170_V	0.854	1.00
395_A	449_V	0.854	1.00
533_K	536_E	0.851	1.00
229_L	257_G	0.851	1.00
73_G	435_A	0.851	1.00
458_Q	461_L	0.851	1.00
49_D	52_Y	0.851	1.00
469_E	506_S	0.850	1.00
394_E	416_K	0.849	1.00
222_I	290_I	0.849	1.00
482_A	552_S	0.848	1.00
455_G	484_L	0.848	1.00
77_V	421_V	0.846	1.00
27_S	30_K	0.840	1.00
106_S	166_R	0.840	1.00
451_V	479_L	0.839	1.00
46_P	180_T	0.836	1.00
202_P	207_I	0.835	1.00
70_A	467_I	0.834	1.00
386_Y	530_A	0.833	1.00
467_I	543_P	0.832	1.00
269_A	281_L	0.831	1.00
219_K	285_D	0.830	1.00
174_I	179_A	0.830	1.00
384_I	479_L	0.829	1.00
260_A	265_F	0.829	1.00
141_H	158_A	0.828	1.00
97_T	428_T	0.828	1.00
204_Y	208_R	0.827	1.00
390_F	538_L	0.827	1.00
233_A	236_E	0.826	1.00
207_I	341_E	0.822	1.00
35_M	74_Y	0.820	1.00
261_D	393_G	0.818	1.00
536_E	540_S	0.816	1.00
358_Q	361_E	0.813	1.00
96_V	135_T	0.813	1.00
110_V	163_T	0.805	1.00
474_V	543_P	0.804	1.00
352_S	356_K	0.802	1.00
449_V	477_V	0.799	1.00
224_A	250_H	0.798	1.00
509_D	523_R	0.798	1.00
321_I	330_P	0.794	1.00
362_W	366_Y	0.793	1.00
528_A	532_E	0.792	1.00
83_V	110_V	0.791	1.00
259_P	262_H	0.789	1.00
437_I	472_L	0.787	1.00
19_S	50_K	0.786	1.00
480_N	549_R	0.784	1.00
85_I	112_F	0.783	1.00
210_L	338_V	0.781	1.00
384_I	412_Y	0.781	1.00
378_F	527_E	0.780	1.00
224_A	248_V	0.780	1.00
259_P	415_Q	0.779	1.00
148_P	152_P	0.778	1.00
141_H	157_E	0.776	1.00
69_H	428_T	0.775	1.00
209_K	329_I	0.771	1.00
34_E	74_Y	0.771	1.00
475_K	541_R	0.771	1.00
140_K	170_V	0.771	1.00
75_A	107_L	0.770	1.00
40_P	60_L	0.770	1.00
341_E	345_Q	0.769	1.00
340_Q	344_K	0.768	1.00
77_V	442_A	0.768	1.00
436_A	474_V	0.767	1.00
388_H	415_Q	0.765	1.00
74_Y	80_K	0.764	1.00
141_H	170_V	0.764	1.00
433_L	476_V	0.764	1.00
286_L	310_K	0.761	1.00
318_P	332_V	0.761	1.00
215_S	344_K	0.760	1.00
49_D	498_R	0.758	1.00
509_D	515_E	0.757	1.00
399_T	422_T	0.756	1.00
31_E	163_T	0.756	1.00
391_T	395_A	0.755	1.00
215_S	345_Q	0.755	1.00
468_R	543_P	0.750	1.00
33_V	159_F	0.748	1.00
160_H	164_T	0.747	1.00
399_T	420_W	0.747	1.00
100_A	138_V	0.746	1.00
144_Q	173_D	0.745	1.00
61_P	66_G	0.740	1.00
233_A	336_K	0.736	1.00
404_H	456_G	0.735	1.00
44_V	48_Y	0.735	1.00
36_I	85_I	0.731	1.00
212_E	349_Q	0.730	1.00
28_L	83_V	0.730	1.00
29_K	34_E	0.728	1.00
288_I	314_I	0.727	1.00
140_K	161_I	0.727	1.00
199_T	334_D	0.727	1.00
488_R	492_E	0.726	1.00
37_F	70_A	0.726	1.00
228_V	257_G	0.724	1.00
396_I	446_A	0.722	1.00
65_Q	94_N	0.722	1.00
232_K	418_D	0.722	1.00
521_G	547_D	0.722	1.00
220_P	246_I	0.720	1.00
234_S	417_A	0.720	1.00
338_V	341_E	0.719	1.00
219_K	355_W	0.716	1.00
148_P	183_G	0.716	1.00
250_H	260_A	0.715	1.00
258_F	265_F	0.715	1.00
344_K	347_G	0.715	1.00
340_Q	343_I	0.714	1.00
202_P	337_I	0.714	1.00
313_H	327_T	0.713	1.00
49_D	53_N	0.711	1.00
458_Q	508_P	0.709	1.00
86_A	113_T	0.708	1.00
113_T	173_D	0.707	1.00
451_V	477_V	0.706	1.00
399_T	408_S	0.705	1.00
118_T	146_R	0.702	1.00
398_A	421_V	0.701	1.00
270_G	273_G	0.698	1.00
355_W	366_Y	0.697	1.00
75_A	109_L	0.697	1.00
252_L	409_A	0.697	1.00
220_P	286_L	0.696	1.00
476_V	519_I	0.696	1.00
44_V	85_I	0.695	1.00
206_Q	331_V	0.695	1.00
468_R	506_S	0.695	1.00
99_L	138_V	0.694	1.00
157_E	160_H	0.694	1.00
467_I	472_L	0.693	1.00
477_V	530_A	0.693	1.00
400_D	432_G	0.692	0.99
398_A	439_A	0.692	0.99
468_R	518_G	0.691	0.99
213_A	216_S	0.691	0.99
39_Y	95_L	0.689	0.99
47_I	179_A	0.687	0.99
148_P	178_V	0.687	0.99
378_F	526_S	0.686	0.99
132_L	136_M	0.685	0.99
354_E	358_Q	0.684	0.99
458_Q	510_F	0.683	0.99
206_Q	210_L	0.681	0.99
93_T	96_V	0.681	0.99
161_I	166_R	0.681	0.99
226_A	253_L	0.679	0.99
201_E	204_Y	0.679	0.99
102_A	109_L	0.678	0.99
355_W	358_Q	0.675	0.99
524_I	546_I	0.674	0.99
447_T	473_P	0.673	0.99
450_A	456_G	0.671	0.99
74_Y	82_G	0.671	0.99
30_K	189_H	0.670	0.99
68_I	111_V	0.669	0.99
508_P	516_A	0.669	0.99
449_V	475_K	0.669	0.99
218_K	285_D	0.667	0.99
433_L	463_E	0.667	0.99
103_M	140_K	0.667	0.99
223_L	289_S	0.663	0.99
299_T	303_K	0.662	0.99
279_M	282_H	0.661	0.99
87_T	127_Q	0.661	0.99
245_Q	263_P	0.660	0.99
383_L	477_V	0.658	0.99
152_P	156_K	0.657	0.99
107_L	431_F	0.657	0.99
135_T	171_L	0.656	0.99
35_M	80_K	0.656	0.99
457_F	510_F	0.655	0.99
154_I	157_E	0.655	0.99
433_L	452_V	0.654	0.99
473_P	543_P	0.653	0.99
436_A	448_V	0.653	0.99
488_R	504_F	0.652	0.99
345_Q	348_K	0.651	0.99
343_I	347_G	0.650	0.99
483_C	488_R	0.650	0.99
533_K	544_V	0.643	0.99
519_I	542_E	0.643	0.99
214_V	244_Q	0.641	0.99
441_L	470_L	0.641	0.99
492_E	499_Y	0.640	0.99
47_I	85_I	0.638	0.99
376_E	526_S	0.637	0.99
118_T	175_P	0.637	0.99
46_P	179_A	0.635	0.99
227_G	315_D	0.629	0.99
541_R	544_V	0.628	0.99
145_V	175_P	0.628	0.99
231_G	334_D	0.628	0.99
158_A	172_I	0.626	0.99
94_N	97_T	0.626	0.99
338_V	342_L	0.625	0.99
236_E	240_Y	0.625	0.99
62_R	469_E	0.624	0.99
398_A	432_G	0.623	0.99
44_V	114_G	0.621	0.99
207_I	342_L	0.621	0.99
437_I	466_V	0.621	0.99
222_I	248_V	0.620	0.99
237_L	241_A	0.620	0.99
104_I	426_L	0.619	0.99
289_S	311_I	0.618	0.99
434_P	463_E	0.618	0.99
241_A	244_Q	0.618	0.99
522_I	540_S	0.615	0.99
223_L	251_T	0.614	0.99
36_I	56_L	0.612	0.99
312_A	329_I	0.612	0.99
93_T	129_A	0.611	0.99
74_Y	78_S	0.611	0.99
391_T	412_Y	0.610	0.99
452_V	476_V	0.609	0.99
387_I	477_V	0.608	0.99
69_H	101_D	0.608	0.99
364_E	367_P	0.607	0.99
266_L	277_A	0.607	0.99
509_D	547_D	0.606	0.99
73_G	438_G	0.606	0.99
207_I	331_V	0.605	0.99
421_V	431_F	0.605	0.99
243_Q	346_D	0.605	0.99
263_P	360_A	0.605	0.99
223_L	292_A	0.603	0.99
20_G	23_M	0.600	0.99
439_A	448_V	0.599	0.99
52_Y	498_R	0.598	0.99
404_H	479_L	0.597	0.99
244_Q	264_L	0.596	0.99
278_N	282_H	0.594	0.98
177_D	181_I	0.594	0.98
452_V	460_T	0.592	0.98
335_S	340_Q	0.591	0.98
113_T	131_I	0.591	0.98
29_K	56_L	0.591	0.98
376_E	527_E	0.590	0.98
57_V	444_K	0.590	0.98
239_N	344_K	0.589	0.98
522_I	532_E	0.589	0.98
57_V	441_L	0.589	0.98
264_L	356_K	0.588	0.98
396_I	421_V	0.588	0.98
63_H	94_N	0.588	0.98
115_Q	144_Q	0.587	0.98
356_K	359_L	0.587	0.98
433_L	467_I	0.587	0.98
274_T	368_L	0.586	0.98
457_F	476_V	0.585	0.98
108_P	162_A	0.585	0.98
359_L	367_P	0.584	0.98
118_T	147_Q	0.583	0.98
238_K	416_K	0.583	0.98
140_K	166_R	0.581	0.98
468_R	471_N	0.581	0.98
199_T	337_I	0.580	0.98
22_L	54_S	0.580	0.98
320_E	323_K	0.579	0.98
233_A	335_S	0.579	0.98
359_L	366_Y	0.578	0.98
377_G	551_A	0.578	0.98
526_S	532_E	0.578	0.98
26_E	54_S	0.578	0.98
70_A	441_L	0.577	0.98
475_K	542_E	0.576	0.98
399_T	432_G	0.575	0.98
112_F	155_I	0.575	0.98
215_S	218_K	0.574	0.98
143_Y	170_V	0.572	0.98
18_M	22_L	0.571	0.98
383_L	530_A	0.571	0.98
77_V	396_I	0.571	0.98
81_P	162_A	0.571	0.98
534_L	538_L	0.570	0.98
382_K	531_K	0.570	0.98
255_L	414_F	0.569	0.98
72_E	435_A	0.567	0.98
34_E	78_S	0.566	0.98
229_L	418_D	0.566	0.98
27_S	152_P	0.566	0.98
394_E	447_T	0.565	0.98
159_F	163_T	0.564	0.98
245_Q	356_K	0.564	0.98
315_D	320_E	0.562	0.98
83_V	159_F	0.562	0.98
471_N	542_E	0.562	0.98
461_L	516_A	0.562	0.98
118_T	178_V	0.561	0.98
112_F	172_I	0.561	0.98
395_A	446_A	0.560	0.98
508_P	513_L	0.560	0.98
192_N	195_G	0.560	0.98
497_E	500_S	0.559	0.98
205_L	209_K	0.556	0.98
203_N	337_I	0.555	0.98
110_V	170_V	0.555	0.98
30_K	185_F	0.555	0.98
95_L	113_T	0.555	0.98
245_Q	352_S	0.554	0.98
67_A	84_V	0.553	0.98
166_R	317_D	0.553	0.98
229_L	234_S	0.552	0.98
39_Y	484_L	0.552	0.98
321_I	327_T	0.551	0.98
202_P	333_G	0.551	0.98
115_Q	121_I	0.551	0.98
256_G	260_A	0.549	0.97
75_A	81_P	0.549	0.97
488_R	552_S	0.549	0.97
100_A	129_A	0.549	0.97
126_F	427_G	0.548	0.97
253_L	424_G	0.548	0.97
524_I	532_E	0.548	0.97
476_V	545_V	0.548	0.97
23_M	185_F	0.547	0.97
235_E	242_E	0.545	0.97
367_P	413_P	0.545	0.97
487_V	491_Q	0.544	0.97
221_V	280_A	0.544	0.97
149_E	184_E	0.544	0.97
95_L	98_G	0.543	0.97
356_K	363_K	0.542	0.97
62_R	465_D	0.541	0.97
161_I	164_T	0.541	0.97
148_P	151_L	0.541	0.97
218_K	354_E	0.541	0.97
110_V	172_I	0.540	0.97
250_H	255_L	0.539	0.97
68_I	99_L	0.539	0.97
76_R	105_D	0.539	0.97
458_Q	462_Q	0.539	0.97
465_D	508_P	0.539	0.97
27_S	159_F	0.538	0.97
131_I	171_L	0.538	0.97
536_E	544_V	0.538	0.97
122_G	128_E	0.537	0.97
210_L	342_L	0.535	0.97
103_M	139_T	0.535	0.97
380_P	407_W	0.534	0.97
238_K	241_A	0.534	0.97
398_A	435_A	0.533	0.97
140_K	164_T	0.532	0.97
245_Q	348_K	0.531	0.97
122_G	125_A	0.531	0.97
391_T	538_L	0.530	0.97
384_I	388_H	0.530	0.97
25_I	51_L	0.530	0.97
52_Y	500_S	0.529	0.97
37_F	441_L	0.529	0.97
20_G	181_I	0.528	0.97
463_E	466_V	0.527	0.97
452_V	456_G	0.527	0.97
59_I	466_V	0.527	0.97
527_E	531_K	0.526	0.97
408_S	420_W	0.526	0.97
215_S	348_K	0.525	0.97
198_P	203_N	0.525	0.97
381_Q	554_E	0.524	0.97
101_D	105_D	0.524	0.97
384_I	408_S	0.524	0.97
206_Q	329_I	0.523	0.97
41_G	87_T	0.522	0.97
150_D	154_I	0.522	0.97
199_T	203_N	0.522	0.97
145_V	172_I	0.522	0.97
509_D	516_A	0.522	0.97
42_G	87_T	0.522	0.97
160_H	163_T	0.520	0.97
223_L	287_L	0.520	0.97
45_L	502_S	0.518	0.96
39_Y	61_P	0.518	0.96
475_K	540_S	0.515	0.96
86_A	92_A	0.515	0.96
466_V	472_L	0.514	0.96
81_P	84_V	0.514	0.96
250_H	257_G	0.513	0.96
468_R	542_E	0.512	0.96
103_M	168_G	0.511	0.96
508_P	517_Y	0.511	0.96
42_G	490_W	0.509	0.96
32_K	80_K	0.508	0.96
75_A	82_G	0.508	0.96
317_D	320_E	0.508	0.96
414_F	419_K	0.506	0.96
382_K	385_E	0.506	0.96
232_K	336_K	0.506	0.96
433_L	461_L	0.506	0.96
374_E	528_A	0.505	0.96
466_V	470_L	0.505	0.96
480_N	510_F	0.505	0.96
53_N	496_E	0.505	0.96
254_G	257_G	0.504	0.96
515_E	522_I	0.504	0.96
145_V	174_I	0.504	0.96
204_Y	344_K	0.504	0.96
82_G	87_T	0.503	0.96
65_Q	460_T	0.502	0.96
152_P	155_I	0.502	0.96
397_V	420_W	0.502	0.96
520_K	541_R	0.502	0.96
416_K	446_A	0.502	0.96
210_L	288_I	0.501	0.96
399_T	402_G	0.501	0.96
238_K	264_L	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ozhA	4	0.9477	100	0.181	Contact Map
1ybhA	4	0.9791	100	0.185	Contact Map
2panA	3	0.9686	100	0.188	Contact Map
4rjjA	5	0.9582	100	0.189	Contact Map
1t9bA	2	0.9774	100	0.19	Contact Map
2uz1A	4	0.9477	100	0.193	Contact Map
2ihtA	4	0.9425	100	0.194	Contact Map
2pgnA	4	0.9512	100	0.197	Contact Map
3eyaA	5	0.9129	100	0.202	Contact Map
2x7jA	4	0.9756	100	0.203	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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