RBSK - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

RBSK - Ribokinase

UniProt:	P36945	Sequences: MRNICVIGSCSMDLVVTSDKRPKAGETVLGTSFQTVPGGKGANQAVAAARLGAQVFMVGKVGDDHYGTAILNNLKANGVRTDYMEPVTHTESGTAHIVLAEGDNSIVVVKGANDDITPAYALNALEQIEKVDMVLIQQEIPEETVDEVCKYCHSHDIPIILNPAPARPLKQETIDHATYLTPNEHEASILFPELTISEALALYPAKLFITEGKQGVRYSAGSKEVLIPSFPVEPVDTTGAGDTFNAAFAVALAEGKDIEAALRFANRAASLSVCSFGAQGGMPTRNEVEELLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	293 (270)
Sequences:	22426 (16671)
Seq/√Len:	1014.5

ECOLI - SQUV RBSK YDJH PSUK YEII YEGV PFKB KDGK K1PF FRLD HLDE INGK
BACSU - RBSK IOLC KDGK YDJE K1PF FRLD
HALSA - Q9HP13 Q9HMJ3 Q9HSM7
SULSO - KDGK Q981E2 Q97W01 Q980X6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
53_A	250_V	3.174	1.00
135_L	160_I	2.793	1.00
71_L	86_P	2.661	1.00
211_E	217_R	2.547	1.00
56_F	80_R	2.534	1.00
218_Y	262_L	2.488	1.00
257_D	260_A	2.423	1.00
251_A	256_K	2.353	1.00
216_V	244_F	2.311	1.00
5_C	131_V	2.292	1.00
48_A	53_A	2.186	1.00
150_K	176_H	2.180	1.00
68_T	86_P	2.178	1.00
50_R	77_N	2.072	1.00
60_K	87_V	2.055	1.00
6_V	45_A	2.037	1.00
184_E	211_E	2.006	1.00
160_I	249_A	2.001	1.00
152_C	157_I	1.965	1.00
251_A	264_F	1.949	1.00
243_T	268_A	1.944	1.00
46_V	77_N	1.866	1.00
225_V	259_E	1.847	1.00
178_T	205_A	1.840	1.00
149_C	159_I	1.830	1.00
133_M	158_P	1.827	1.00
181_T	245_N	1.824	1.00
158_P	178_T	1.804	1.00
60_K	120_Y	1.774	1.00
218_Y	225_V	1.771	1.00
47_A	246_A	1.763	1.00
216_V	266_N	1.756	1.00
256_K	260_A	1.750	1.00
240_A	273_V	1.748	1.00
72_N	76_A	1.735	1.00
75_K	81_T	1.726	1.00
200_L	219_S	1.716	1.00
73_N	76_A	1.698	1.00
133_M	160_I	1.693	1.00
211_E	226_L	1.686	1.00
71_L	75_K	1.675	1.00
230_F	267_R	1.675	1.00
269_A	273_V	1.669	1.00
217_R	226_L	1.665	1.00
259_E	263_R	1.665	1.00
247_A	268_A	1.664	1.00
248_F	261_A	1.653	1.00
195_T	198_E	1.632	1.00
179_Y	206_K	1.632	1.00
146_D	172_E	1.616	1.00
48_A	250_V	1.600	1.00
208_F	248_F	1.554	1.00
236_D	277_G	1.545	1.00
68_T	72_N	1.541	1.00
10_C	59_G	1.534	1.00
147_E	150_K	1.526	1.00
188_S	194_L	1.524	1.00
162_N	210_T	1.522	1.00
206_K	220_A	1.508	1.00
133_M	249_A	1.508	1.00
218_Y	258_I	1.502	1.00
220_A	223_K	1.501	1.00
63_D	68_T	1.494	1.00
4_I	48_A	1.479	1.00
227_I	262_L	1.472	1.00
247_A	264_F	1.468	1.00
146_D	150_K	1.463	1.00
35_T	69_A	1.455	1.00
163_P	182_P	1.450	1.00
37_P	70_I	1.447	1.00
151_Y	155_H	1.439	1.00
153_H	178_T	1.435	1.00
147_E	151_Y	1.424	1.00
211_E	214_Q	1.420	1.00
90_T	115_D	1.416	1.00
158_P	179_Y	1.389	1.00
177_A	180_L	1.368	1.00
151_Y	154_S	1.360	1.00
129_E	155_H	1.355	1.00
42_A	74_L	1.353	1.00
17_T	32_S	1.343	1.00
12_M	69_A	1.342	1.00
230_F	263_R	1.336	1.00
153_H	176_H	1.335	1.00
232_V	274_C	1.332	1.00
250_V	254_E	1.331	1.00
54_Q	80_R	1.324	1.00
63_D	86_P	1.324	1.00
227_I	266_N	1.323	1.00
67_G	92_S	1.311	1.00
71_L	84_M	1.297	1.00
14_L	33_F	1.270	1.00
219_S	224_E	1.268	1.00
248_F	252_L	1.260	1.00
216_V	262_L	1.259	1.00
206_K	252_L	1.241	1.00
210_T	244_F	1.236	1.00
211_E	215_G	1.228	1.00
230_F	266_N	1.225	1.00
37_P	73_N	1.222	1.00
206_K	248_F	1.220	1.00
260_A	263_R	1.213	1.00
181_T	210_T	1.213	1.00
73_N	77_N	1.212	1.00
49_A	79_V	1.208	1.00
251_A	261_A	1.205	1.00
206_K	258_I	1.205	1.00
232_V	273_V	1.201	1.00
248_F	265_A	1.198	1.00
271_L	275_S	1.192	1.00
247_A	265_A	1.190	1.00
72_N	75_K	1.189	1.00
87_V	90_T	1.189	1.00
158_P	205_A	1.188	1.00
107_V	111_G	1.186	1.00
234_P	273_V	1.183	1.00
51_L	247_A	1.172	1.00
68_T	71_L	1.167	1.00
69_A	72_N	1.164	1.00
14_L	35_T	1.163	1.00
193_E	198_E	1.158	1.00
187_A	209_I	1.145	1.00
271_L	274_C	1.142	1.00
48_A	55_V	1.142	1.00
117_T	120_Y	1.140	1.00
230_F	270_S	1.135	1.00
118_P	147_E	1.127	1.00
44_Q	135_L	1.117	1.00
179_Y	248_F	1.117	1.00
45_A	55_V	1.115	1.00
136_I	159_I	1.103	1.00
134_V	152_C	1.102	1.00
53_A	253_A	1.096	1.00
234_P	237_T	1.087	1.00
184_E	214_Q	1.079	1.00
150_K	154_S	1.076	1.00
46_V	50_R	1.073	1.00
206_K	218_Y	1.064	1.00
47_A	243_T	1.064	1.00
53_A	254_E	1.059	1.00
65_H	68_T	1.050	1.00
229_S	266_N	1.041	1.00
61_V	67_G	1.037	1.00
63_D	89_H	1.037	1.00
251_A	254_E	1.035	1.00
135_L	249_A	1.034	1.00
49_A	78_G	1.028	1.00
266_N	269_A	1.023	1.00
122_L	147_E	1.019	1.00
243_T	272_S	1.016	1.00
161_L	177_A	1.016	1.00
10_C	70_I	1.012	1.00
179_Y	252_L	1.011	1.00
6_V	41_G	1.009	1.00
134_V	157_I	0.997	1.00
261_A	265_A	0.991	1.00
61_V	71_L	0.986	1.00
263_R	267_R	0.985	1.00
181_T	248_F	0.983	1.00
135_L	245_N	0.982	1.00
48_A	246_A	0.981	1.00
56_F	83_Y	0.980	1.00
250_V	264_F	0.969	1.00
17_T	34_Q	0.967	1.00
223_K	259_E	0.965	1.00
7_I	134_V	0.964	1.00
62_G	92_S	0.961	1.00
248_F	258_I	0.961	1.00
51_L	268_A	0.958	1.00
87_V	115_D	0.954	1.00
56_F	131_V	0.952	1.00
143_E	147_E	0.950	1.00
183_N	186_E	0.949	1.00
37_P	69_A	0.948	1.00
234_P	274_C	0.943	1.00
15_V	36_V	0.937	1.00
5_C	58_V	0.933	1.00
49_A	54_Q	0.932	1.00
131_V	157_I	0.931	1.00
61_V	84_M	0.924	1.00
69_A	73_N	0.923	1.00
215_G	229_S	0.923	1.00
126_E	129_E	0.922	1.00
56_F	127_Q	0.921	1.00
71_L	81_T	0.917	1.00
81_T	84_M	0.912	1.00
256_K	264_F	0.910	1.00
16_V	96_H	0.908	1.00
10_C	42_A	0.908	1.00
10_C	57_M	0.907	1.00
64_D	92_S	0.906	1.00
214_Q	226_L	0.905	1.00
184_E	188_S	0.901	1.00
14_L	66_Y	0.899	1.00
107_V	110_K	0.897	1.00
4_I	253_A	0.896	1.00
42_A	279_Q	0.891	1.00
136_I	149_C	0.887	1.00
233_E	274_C	0.886	1.00
252_L	261_A	0.881	1.00
150_K	172_E	0.869	1.00
257_D	261_A	0.863	1.00
182_P	187_A	0.860	1.00
11_S	93_G	0.853	1.00
167_R	170_K	0.853	1.00
197_S	224_E	0.850	1.00
144_T	148_V	0.850	1.00
71_L	85_E	0.849	1.00
136_I	145_V	0.846	1.00
14_L	94_T	0.846	1.00
162_N	181_T	0.844	1.00
225_V	262_L	0.838	1.00
243_T	269_A	0.838	1.00
243_T	247_A	0.836	1.00
244_F	266_N	0.833	1.00
61_V	86_P	0.827	1.00
160_I	181_T	0.825	1.00
13_D	38_G	0.824	1.00
113_N	116_I	0.822	1.00
44_Q	245_N	0.822	1.00
175_D	203_Y	0.819	1.00
227_I	263_R	0.819	1.00
70_I	92_S	0.814	1.00
235_V	276_F	0.813	1.00
60_K	85_E	0.812	1.00
213_K	231_P	0.811	1.00
24_A	103_D	0.811	1.00
172_E	175_D	0.810	1.00
162_N	182_P	0.809	1.00
174_I	177_A	0.807	1.00
232_V	270_S	0.794	1.00
220_A	258_I	0.791	1.00
267_R	271_L	0.790	1.00
247_A	251_A	0.790	1.00
227_I	259_E	0.789	1.00
5_C	56_F	0.784	1.00
12_M	66_Y	0.782	1.00
196_I	199_A	0.781	1.00
45_A	57_M	0.776	1.00
128_I	131_V	0.774	1.00
49_A	55_V	0.774	1.00
127_Q	131_V	0.773	1.00
103_D	106_I	0.773	1.00
128_I	157_I	0.765	1.00
138_Q	161_L	0.760	1.00
7_I	148_V	0.759	1.00
85_E	120_Y	0.755	1.00
266_N	270_S	0.747	1.00
149_C	176_H	0.744	1.00
217_R	224_E	0.739	1.00
12_M	35_T	0.738	1.00
269_A	272_S	0.736	1.00
30_G	107_V	0.736	1.00
116_I	120_Y	0.736	1.00
56_F	82_D	0.730	1.00
105_S	108_V	0.729	1.00
146_D	176_H	0.728	1.00
133_M	253_A	0.727	1.00
46_V	279_Q	0.723	1.00
220_A	225_V	0.723	1.00
215_G	226_L	0.723	1.00
35_T	66_Y	0.720	1.00
116_I	121_A	0.718	1.00
120_Y	123_N	0.711	1.00
208_F	218_Y	0.711	1.00
104_N	108_V	0.710	1.00
51_L	250_V	0.710	1.00
23_K	26_E	0.710	1.00
38_G	43_N	0.703	1.00
54_Q	132_D	0.700	1.00
73_N	279_Q	0.700	1.00
40_K	164_A	0.699	1.00
160_I	179_Y	0.697	1.00
244_F	262_L	0.695	1.00
108_V	111_G	0.682	1.00
244_F	265_A	0.681	1.00
256_K	261_A	0.681	1.00
83_Y	127_Q	0.678	1.00
118_P	143_E	0.676	1.00
97_I	106_I	0.676	1.00
51_L	264_F	0.674	1.00
66_Y	94_T	0.673	1.00
143_E	146_D	0.668	1.00
146_D	149_C	0.668	1.00
220_A	224_E	0.662	1.00
244_F	269_A	0.657	1.00
16_V	30_G	0.655	1.00
97_I	238_T	0.655	1.00
148_V	152_C	0.652	1.00
152_C	155_H	0.652	1.00
168_P	171_Q	0.650	1.00
34_Q	276_F	0.648	1.00
132_D	157_I	0.646	1.00
112_A	115_D	0.645	1.00
82_D	127_Q	0.642	1.00
98_V	105_S	0.641	1.00
45_A	79_V	0.638	1.00
160_I	245_N	0.637	1.00
118_P	144_T	0.636	1.00
159_I	177_A	0.633	1.00
48_A	249_A	0.632	1.00
180_L	207_L	0.631	1.00
9_S	139_E	0.626	1.00
5_C	127_Q	0.626	1.00
203_Y	207_L	0.625	1.00
59_G	84_M	0.622	1.00
262_L	266_N	0.621	1.00
16_V	33_F	0.619	1.00
188_S	193_E	0.614	1.00
246_A	250_V	0.613	1.00
68_T	75_K	0.612	1.00
95_A	98_V	0.610	1.00
119_A	122_L	0.609	1.00
51_L	246_A	0.608	1.00
93_G	98_V	0.607	1.00
134_V	148_V	0.606	1.00
85_E	123_N	0.603	1.00
167_R	171_Q	0.602	1.00
252_L	255_G	0.601	1.00
152_C	159_I	0.601	1.00
171_Q	202_L	0.600	1.00
105_S	109_V	0.596	1.00
17_T	276_F	0.594	1.00
4_I	53_A	0.594	1.00
40_K	139_E	0.593	1.00
133_M	179_Y	0.591	1.00
64_D	67_G	0.590	1.00
44_Q	249_A	0.590	1.00
42_A	57_M	0.590	1.00
145_V	148_V	0.588	1.00
238_T	278_A	0.588	1.00
204_P	207_L	0.586	1.00
118_P	122_L	0.585	1.00
260_A	264_F	0.585	1.00
27_T	40_K	0.584	1.00
216_V	227_I	0.583	1.00
49_A	77_N	0.576	1.00
91_E	94_T	0.576	1.00
93_G	113_N	0.576	1.00
149_C	173_T	0.576	1.00
37_P	279_Q	0.576	1.00
227_I	230_F	0.571	1.00
208_F	244_F	0.570	1.00
87_V	120_Y	0.569	1.00
98_V	107_V	0.567	1.00
90_T	93_G	0.566	1.00
83_Y	86_P	0.563	1.00
113_N	117_T	0.563	1.00
162_N	242_D	0.562	1.00
132_D	158_P	0.561	1.00
181_T	208_F	0.559	1.00
9_S	164_A	0.559	1.00
122_L	126_E	0.557	1.00
185_H	189_I	0.555	1.00
54_Q	253_A	0.555	1.00
187_A	219_S	0.552	1.00
42_A	46_V	0.550	1.00
182_P	210_T	0.548	1.00
74_L	79_V	0.547	1.00
135_L	139_E	0.545	1.00
127_Q	130_K	0.544	1.00
187_A	199_A	0.544	1.00
258_I	261_A	0.542	1.00
213_K	234_P	0.541	1.00
90_T	112_A	0.537	1.00
123_N	126_E	0.537	1.00
258_I	262_L	0.532	1.00
210_T	242_D	0.532	1.00
197_S	226_L	0.531	1.00
135_L	138_Q	0.531	1.00
41_G	45_A	0.530	1.00
186_E	191_F	0.530	1.00
13_D	95_A	0.530	1.00
17_T	99_L	0.530	1.00
43_N	278_A	0.529	1.00
133_M	252_L	0.529	1.00
152_C	156_D	0.526	1.00
17_T	100_A	0.525	1.00
208_F	262_L	0.525	1.00
166_A	189_I	0.521	1.00
160_I	252_L	0.521	1.00
63_D	87_V	0.520	1.00
10_C	74_L	0.520	1.00
46_V	79_V	0.517	1.00
177_A	204_P	0.514	1.00
12_M	70_I	0.514	1.00
6_V	48_A	0.514	1.00
191_F	199_A	0.513	1.00
212_G	237_T	0.512	1.00
74_L	81_T	0.512	1.00
55_V	79_V	0.511	1.00
255_G	261_A	0.510	1.00
44_Q	48_A	0.510	1.00
95_A	139_E	0.509	1.00
93_G	97_I	0.509	1.00
184_E	212_G	0.509	1.00
148_V	151_Y	0.508	1.00
271_L	283_P	0.508	1.00
187_A	207_L	0.508	1.00
254_E	264_F	0.507	1.00
174_I	204_P	0.506	1.00
13_D	278_A	0.502	1.00
44_Q	246_A	0.500	1.00
153_H	156_D	0.500	1.00
5_C	128_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2rbcA	2	0.9898	100	0.173	Contact Map
3ry7A	2	0.9932	100	0.177	Contact Map
4xdaA	2	1	100	0.179	Contact Map
3ikhA	2	0.9659	100	0.18	Contact Map
1rkdA	2	1	100	0.184	Contact Map
2fv7A	2	1	100	0.19	Contact Map
3go6A	4	0.9454	100	0.206	Contact Map
1vm7A	2	0.9727	100	0.206	Contact Map
3vasA	1	0.9795	100	0.209	Contact Map
3ljsA	2	0.9659	100	0.214	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0103 seconds.