FLHA - BACSU - GREMLIN Contacts

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FLHA - Flagellar biosynthesis protein FlhA

UniProt:	P35620	Sequences: MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSILSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEAKHRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLISTATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEILEEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYRLKIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQHAHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTRQALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPVRMYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	677 (670)
Sequences:	1911 (1134)
Seq/√Len:	43.8

ECOLI - FLHA FHIA
BACSU - FLHA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
213_S	216_E	7.711	1.00
524_K	556_T	7.163	1.00
159_E	162_H	6.563	1.00
275_A	300_A	6.254	1.00
272_Y	303_A	5.585	1.00
199_I	222_T	5.167	1.00
407_E	410_K	4.562	1.00
192_I	196_M	4.555	1.00
101_N	209_Q	4.457	1.00
436_V	443_P	4.426	1.00
275_A	296_A	4.301	1.00
204_V	208_L	4.242	1.00
486_G	489_E	4.236	1.00
51_E	166_K	3.938	1.00
289_I	293_G	3.905	1.00
301_F	305_T	3.894	1.00
413_L	469_V	3.888	1.00
279_M	296_A	3.859	1.00
534_N	537_T	3.587	1.00
509_T	518_I	3.447	1.00
398_E	410_K	3.396	1.00
634_L	655_L	3.344	1.00
531_S	566_Q	3.190	1.00
127_V	248_T	3.136	1.00
414_L	433_I	3.113	1.00
207_M	214_I	3.059	1.00
212_M	216_E	2.943	1.00
196_M	200_I	2.936	1.00
512_P	546_G	2.927	1.00
645_K	649_E	2.870	1.00
494_I	539_F	2.854	1.00
91_E	95_N	2.837	1.00
212_M	220_H	2.796	1.00
272_Y	307_S	2.764	1.00
300_A	304_Y	2.751	1.00
409_A	476_K	2.749	1.00
38_L	65_L	2.706	1.00
648_L	655_L	2.697	1.00
591_I	640_V	2.675	1.00
272_Y	300_A	2.647	1.00
127_V	185_K	2.640	1.00
347_E	391_N	2.639	1.00
297_G	301_F	2.600	1.00
156_T	162_H	2.589	1.00
19_L	74_V	2.561	1.00
51_E	54_Q	2.553	1.00
162_H	166_K	2.523	1.00
447_I	455_A	2.520	1.00
82_S	104_V	2.516	1.00
497_L	539_F	2.483	1.00
493_L	535_L	2.480	1.00
395_Q	398_E	2.468	1.00
542_L	555_L	2.452	1.00
76_T	90_V	2.430	1.00
483_E	565_K	2.418	1.00
33_I	89_V	2.402	1.00
215_Q	218_A	2.374	1.00
28_L	76_T	2.360	1.00
618_V	648_L	2.309	1.00
403_I	408_V	2.294	1.00
513_L	518_I	2.271	1.00
88_K	91_E	2.268	1.00
568_T	664_E	2.262	1.00
18_M	75_S	2.257	1.00
156_T	159_E	2.243	1.00
65_L	239_I	2.235	1.00
417_H	448_S	2.230	1.00
541_T	545_Y	2.228	1.00
399_Y	472_H	2.172	1.00
50_Q	54_Q	2.168	1.00
419_L	435_T	2.124	1.00
513_L	517_D	2.112	0.99
480_H	483_E	2.103	0.99
127_V	243_T	2.095	0.99
122_K	125_E	2.062	0.99
84_G	212_M	2.049	0.99
42_V	65_L	2.042	0.99
279_M	293_G	2.002	0.99
485_I	490_T	1.996	0.99
451_V	454_E	1.986	0.99
638_P	659_S	1.963	0.99
114_I	193_I	1.940	0.99
185_K	243_T	1.931	0.99
16_V	75_S	1.928	0.99
404_K	534_N	1.925	0.99
200_I	204_V	1.921	0.99
282_G	289_I	1.917	0.99
33_I	292_T	1.890	0.99
634_L	644_V	1.885	0.99
103_L	204_V	1.869	0.99
158_Q	161_K	1.865	0.99
618_V	634_L	1.862	0.99
434_E	445_K	1.860	0.99
216_E	220_H	1.846	0.99
371_I	470_S	1.834	0.99
420_A	447_I	1.833	0.99
346_F	469_V	1.824	0.98
106_L	226_V	1.801	0.98
41_I	274_A	1.796	0.98
513_L	542_L	1.766	0.98
157_E	161_K	1.752	0.98
210_Q	221_F	1.741	0.98
531_S	570_Q	1.726	0.98
658_L	669_V	1.719	0.98
464_D	467_S	1.705	0.98
537_T	541_T	1.699	0.98
165_E	169_R	1.699	0.98
621_E	624_Q	1.693	0.98
344_I	477_I	1.693	0.98
74_V	112_L	1.680	0.97
307_S	311_K	1.670	0.97
55_F	61_L	1.660	0.97
19_L	112_L	1.652	0.97
76_T	228_D	1.636	0.97
120_I	236_A	1.605	0.97
298_L	302_G	1.595	0.96
203_I	214_I	1.587	0.96
494_I	515_V	1.581	0.96
638_P	661_N	1.578	0.96
587_V	614_I	1.573	0.96
106_L	218_A	1.570	0.96
116_Q	517_D	1.568	0.96
71_G	75_S	1.557	0.96
282_G	293_G	1.549	0.96
414_L	417_H	1.545	0.96
423_P	461_T	1.532	0.95
571_F	656_P	1.514	0.95
485_I	522_L	1.490	0.95
298_L	301_F	1.482	0.95
648_L	657_V	1.481	0.95
212_M	217_A	1.474	0.94
521_V	542_L	1.471	0.94
505_V	539_F	1.470	0.94
76_T	79_S	1.461	0.94
12_V	64_L	1.460	0.94
480_H	636_C	1.459	0.94
549_T	554_L	1.457	0.94
381_L	532_I	1.451	0.94
216_E	219_S	1.442	0.94
57_I	61_L	1.428	0.93
19_L	82_S	1.427	0.93
522_L	532_I	1.426	0.93
491_K	495_D	1.418	0.93
124_A	221_F	1.410	0.93
203_I	217_A	1.405	0.93
12_V	47_M	1.397	0.93
401_L	476_K	1.390	0.92
76_T	191_G	1.386	0.92
165_E	168_A	1.371	0.92
16_V	238_L	1.364	0.92
64_L	245_I	1.363	0.92
530_V	571_F	1.357	0.92
350_Y	396_P	1.352	0.91
530_V	570_Q	1.348	0.91
82_S	99_G	1.348	0.91
110_I	196_M	1.346	0.91
379_L	481_A	1.344	0.91
591_I	644_V	1.344	0.91
357_D	362_G	1.343	0.91
188_A	236_A	1.330	0.91
203_I	207_M	1.330	0.91
344_I	403_I	1.329	0.91
497_L	535_L	1.326	0.91
302_G	305_T	1.324	0.91
595_V	643_Y	1.322	0.90
509_T	539_F	1.311	0.90
595_V	602_N	1.309	0.90
275_A	279_M	1.303	0.90
341_I	490_T	1.301	0.90
375_L	379_L	1.299	0.90
191_G	228_D	1.299	0.90
313_K	316_V	1.294	0.89
118_I	191_G	1.291	0.89
267_Y	270_L	1.291	0.89
418_Y	449_E	1.289	0.89
102_V	199_I	1.289	0.89
401_L	473_I	1.286	0.89
308_K	312_E	1.285	0.89
154_M	157_E	1.284	0.89
5_D	269_K	1.281	0.89
216_E	298_L	1.280	0.89
487_R	519_Q	1.274	0.89
39_A	191_G	1.268	0.88
25_P	83_H	1.257	0.88
357_D	360_Q	1.256	0.88
552_S	556_T	1.256	0.88
400_R	410_K	1.250	0.88
514_S	517_D	1.249	0.88
45_T	264_L	1.246	0.88
348_F	354_P	1.243	0.87
279_M	297_G	1.243	0.87
73_N	191_G	1.240	0.87
35_N	239_I	1.235	0.87
502_P	506_E	1.234	0.87
82_S	98_V	1.232	0.87
167_V	171_A	1.226	0.87
46_T	246_V	1.221	0.87
534_N	566_Q	1.221	0.87
398_E	412_E	1.221	0.87
122_K	243_T	1.219	0.86
541_T	562_A	1.214	0.86
61_L	260_I	1.209	0.86
581_V	673_G	1.207	0.86
436_V	441_G	1.199	0.86
75_S	185_K	1.194	0.85
428_D	458_L	1.191	0.85
39_A	46_T	1.190	0.85
90_V	102_V	1.190	0.85
463_V	471_T	1.186	0.85
107_V	299_L	1.173	0.84
305_T	308_K	1.170	0.84
285_T	288_G	1.168	0.84
508_V	543_A	1.167	0.84
633_I	656_P	1.167	0.84
367_R	405_G	1.165	0.84
421_M	437_E	1.163	0.84
592_A	639_P	1.161	0.84
225_T	229_G	1.158	0.83
112_L	168_A	1.158	0.83
518_I	542_L	1.155	0.83
545_Y	558_Y	1.147	0.83
16_V	185_K	1.145	0.83
214_I	218_A	1.144	0.83
285_T	292_T	1.141	0.83
420_A	460_Y	1.141	0.83
155_I	163_R	1.141	0.83
498_K	506_E	1.140	0.82
33_I	295_L	1.140	0.82
56_S	263_Q	1.139	0.82
30_I	34_I	1.138	0.82
368_I	467_S	1.134	0.82
114_I	118_I	1.130	0.82
139_M	167_V	1.130	0.82
44_L	171_A	1.128	0.82
413_L	465_P	1.117	0.81
557_E	659_S	1.114	0.81
577_V	670_Q	1.112	0.81
611_S	647_L	1.110	0.81
73_N	76_T	1.108	0.81
407_E	569_A	1.106	0.80
497_L	508_V	1.105	0.80
139_M	239_I	1.105	0.80
98_V	226_V	1.099	0.80
19_L	71_G	1.092	0.80
276_A	303_A	1.092	0.80
490_T	519_Q	1.090	0.80
84_G	220_H	1.089	0.79
106_L	199_I	1.089	0.79
644_V	648_L	1.087	0.79
416_D	465_P	1.084	0.79
583_C	644_V	1.083	0.79
347_E	353_I	1.082	0.79
218_A	222_T	1.080	0.79
272_Y	275_A	1.075	0.79
535_L	539_F	1.074	0.78
73_N	195_V	1.074	0.78
635_L	653_P	1.067	0.78
102_V	222_T	1.066	0.78
18_M	71_G	1.065	0.78
18_M	76_T	1.065	0.78
33_I	287_I	1.064	0.78
455_A	462_V	1.051	0.77
310_G	313_K	1.051	0.77
73_N	232_S	1.044	0.76
199_I	203_I	1.043	0.76
278_I	282_G	1.041	0.76
211_G	216_E	1.041	0.76
350_Y	353_I	1.040	0.76
287_I	291_L	1.039	0.76
232_S	291_L	1.036	0.76
106_L	222_T	1.033	0.76
221_F	225_T	1.030	0.76
114_I	192_I	1.028	0.75
102_V	106_L	1.027	0.75
219_S	223_M	1.026	0.75
70_L	190_A	1.025	0.75
293_G	300_A	1.023	0.75
205_I	209_Q	1.020	0.75
387_R	402_K	1.019	0.75
26_W	30_I	1.018	0.75
5_D	9_L	1.014	0.74
440_F	471_T	1.013	0.74
268_P	310_G	1.012	0.74
61_L	264_L	1.010	0.74
581_V	625_L	1.008	0.74
430_I	451_V	1.004	0.74
157_E	376_A	0.999	0.73
572_A	578_L	0.997	0.73
12_V	19_L	0.995	0.73
226_V	403_I	0.994	0.73
555_L	655_L	0.994	0.73
67_L	242_A	0.992	0.73
455_A	460_Y	0.984	0.72
598_T	601_G	0.983	0.72
314_E	318_E	0.983	0.72
644_V	649_E	0.979	0.72
28_L	75_S	0.978	0.72
25_P	85_E	0.976	0.71
578_L	633_I	0.975	0.71
622_A	652_F	0.975	0.71
211_G	246_V	0.973	0.71
620_K	623_E	0.972	0.71
333_E	337_Q	0.970	0.71
504_L	536_V	0.969	0.71
342_D	347_E	0.968	0.71
345_E	402_K	0.966	0.71
383_I	477_I	0.966	0.71
28_L	79_S	0.965	0.71
197_I	594_G	0.964	0.71
404_K	537_T	0.963	0.70
491_K	499_E	0.962	0.70
503_V	506_E	0.962	0.70
625_L	672_I	0.958	0.70
191_G	225_T	0.957	0.70
37_S	299_L	0.957	0.70
579_K	670_Q	0.954	0.70
618_V	675_V	0.952	0.70
276_A	310_G	0.950	0.69
494_I	518_I	0.947	0.69
272_Y	276_A	0.946	0.69
174_Y	241_T	0.943	0.69
48_N	295_L	0.940	0.69
185_K	274_A	0.940	0.69
23_F	96_F	0.936	0.68
122_K	191_G	0.936	0.68
282_G	292_T	0.934	0.68
576_E	667_V	0.932	0.68
75_S	336_V	0.932	0.68
25_P	79_S	0.932	0.68
98_V	223_M	0.931	0.68
207_M	218_A	0.931	0.68
274_A	278_I	0.931	0.68
315_E	319_I	0.930	0.68
287_I	292_T	0.929	0.68
431_E	451_V	0.928	0.68
495_D	595_V	0.928	0.68
300_A	303_A	0.927	0.67
479_Q	654_D	0.920	0.67
497_L	505_V	0.919	0.67
607_E	610_I	0.918	0.67
531_S	650_R	0.916	0.67
244_G	487_R	0.916	0.67
107_V	257_G	0.913	0.66
116_Q	498_K	0.907	0.66
152_A	158_Q	0.905	0.66
589_K	593_D	0.903	0.65
128_S	488_Q	0.896	0.65
46_T	243_T	0.895	0.65
527_K	649_E	0.895	0.65
564_A	664_E	0.894	0.65
207_M	283_I	0.893	0.65
185_K	189_I	0.891	0.64
214_I	222_T	0.888	0.64
590_A	610_I	0.888	0.64
186_G	233_Q	0.888	0.64
53_L	542_L	0.887	0.64
505_V	518_I	0.886	0.64
309_S	620_K	0.885	0.64
275_A	299_L	0.884	0.64
53_L	201_F	0.883	0.64
507_E	543_A	0.877	0.63
116_Q	568_T	0.875	0.63
395_Q	412_E	0.874	0.63
135_T	138_A	0.874	0.63
579_K	669_V	0.873	0.63
118_I	185_K	0.873	0.63
174_Y	251_A	0.869	0.62
83_H	99_G	0.868	0.62
485_I	532_I	0.866	0.62
67_L	241_T	0.864	0.62
28_L	84_G	0.862	0.62
29_S	288_G	0.862	0.62
572_A	667_V	0.861	0.62
19_L	284_F	0.861	0.62
239_I	244_G	0.861	0.62
272_Y	304_Y	0.860	0.62
319_I	322_E	0.859	0.62
32_I	76_T	0.858	0.61
174_Y	618_V	0.858	0.61
317_D	659_S	0.858	0.61
120_I	152_A	0.858	0.61
636_C	643_Y	0.858	0.61
156_T	163_R	0.856	0.61
422_S	460_Y	0.855	0.61
37_S	278_I	0.853	0.61
579_K	672_I	0.852	0.61
64_L	246_V	0.852	0.61
652_F	655_L	0.851	0.61
199_I	225_T	0.851	0.61
368_I	388_I	0.851	0.61
199_I	495_D	0.848	0.61
356_A	383_I	0.847	0.60
508_V	518_I	0.846	0.60
131_A	169_R	0.845	0.60
490_T	531_S	0.843	0.60
54_Q	282_G	0.841	0.60
172_D	249_R	0.839	0.60
591_I	606_L	0.839	0.60
369_V	640_V	0.839	0.60
118_I	634_L	0.836	0.59
595_V	603_Y	0.835	0.59
108_V	208_L	0.835	0.59
597_Q	602_N	0.832	0.59
261_T	264_L	0.832	0.59
35_N	116_Q	0.832	0.59
442_L	461_T	0.831	0.59
376_A	475_E	0.831	0.59
62_L	199_I	0.831	0.59
116_Q	145_S	0.830	0.59
172_D	280_L	0.829	0.59
212_M	221_F	0.829	0.59
373_R	493_L	0.826	0.58
378_E	474_T	0.826	0.58
174_Y	567_I	0.821	0.58
156_T	452_K	0.820	0.58
8_V	257_G	0.819	0.58
283_I	289_I	0.818	0.58
82_S	115_I	0.816	0.58
304_Y	308_K	0.816	0.58
42_V	50_Q	0.816	0.58
208_L	218_A	0.814	0.57
23_F	27_L	0.814	0.57
195_V	228_D	0.812	0.57
403_I	480_H	0.811	0.57
284_F	292_T	0.810	0.57
221_F	356_A	0.809	0.57
10_I	13_V	0.804	0.56
311_K	316_V	0.804	0.56
92_T	291_L	0.801	0.56
67_L	70_L	0.801	0.56
21_I	75_S	0.800	0.56
426_E	429_L	0.799	0.56
117_F	274_A	0.799	0.56
258_H	513_L	0.797	0.56
85_E	212_M	0.794	0.55
356_A	611_S	0.790	0.55
103_L	201_F	0.789	0.55
477_I	663_L	0.789	0.55
556_T	559_T	0.789	0.55
352_L	368_I	0.788	0.55
185_K	188_A	0.787	0.55
571_F	633_I	0.785	0.55
424_T	460_Y	0.784	0.55
187_D	191_G	0.782	0.54
83_H	86_G	0.782	0.54
254_G	259_D	0.781	0.54
357_D	365_L	0.781	0.54
348_F	356_A	0.781	0.54
453_D	556_T	0.781	0.54
487_R	516_G	0.781	0.54
545_Y	555_L	0.779	0.54
394_L	530_V	0.778	0.54
30_I	167_V	0.777	0.54
34_I	287_I	0.777	0.54
115_I	167_V	0.776	0.54
32_I	287_I	0.772	0.53
47_M	257_G	0.768	0.53
435_T	444_A	0.768	0.53
200_I	359_N	0.768	0.53
77_T	184_V	0.767	0.53
102_V	205_I	0.766	0.53
103_L	604_L	0.765	0.53
110_I	270_L	0.765	0.53
75_S	609_D	0.763	0.53
529_K	578_L	0.761	0.52
233_Q	237_L	0.761	0.52
294_P	324_A	0.761	0.52
117_F	122_K	0.759	0.52
352_L	388_I	0.759	0.52
551_D	601_G	0.759	0.52
485_I	519_Q	0.759	0.52
30_I	207_M	0.759	0.52
98_V	115_I	0.758	0.52
621_E	673_G	0.757	0.52
16_V	64_L	0.756	0.52
346_F	401_L	0.754	0.52
353_I	390_D	0.753	0.52
419_L	461_T	0.752	0.51
486_G	536_V	0.751	0.51
234_I	593_D	0.746	0.51
215_Q	219_S	0.746	0.51
210_Q	216_E	0.745	0.51
128_S	292_T	0.745	0.51
249_R	259_D	0.745	0.51
381_L	569_A	0.743	0.51
610_I	613_S	0.741	0.50
295_L	657_V	0.741	0.50
318_E	327_D	0.740	0.50
48_N	256_L	0.739	0.50
268_P	307_S	0.738	0.50
73_N	228_D	0.737	0.50
507_E	511_N	0.736	0.50
68_F	116_Q	0.736	0.50
524_K	553_D	0.735	0.50
57_I	263_Q	0.734	0.50
448_S	451_V	0.733	0.50
64_L	595_V	0.733	0.50
34_I	38_L	0.731	0.49
159_E	612_E	0.730	0.49
481_A	486_G	0.730	0.49
13_V	269_K	0.728	0.49
145_S	167_V	0.728	0.49
203_I	222_T	0.728	0.49
482_H	527_K	0.726	0.49
140_P	143_Q	0.725	0.49
339_L	376_A	0.725	0.49
635_L	663_L	0.724	0.49
128_S	248_T	0.724	0.49
204_V	222_T	0.723	0.49
33_I	242_A	0.722	0.49
200_I	529_K	0.720	0.48
62_L	239_I	0.719	0.48
15_I	241_T	0.718	0.48
120_I	430_I	0.717	0.48
169_R	252_S	0.716	0.48
357_D	361_G	0.716	0.48
117_F	185_K	0.716	0.48
145_S	411_G	0.715	0.48
114_I	568_T	0.713	0.48
261_T	567_I	0.711	0.48
541_T	576_E	0.711	0.48
553_D	646_Q	0.711	0.48
75_S	116_Q	0.709	0.47
393_A	421_M	0.709	0.47
73_N	90_V	0.709	0.47
318_E	322_E	0.709	0.47
438_P	471_T	0.708	0.47
591_I	643_Y	0.708	0.47
168_A	172_D	0.707	0.47
316_V	322_E	0.707	0.47
106_L	118_I	0.706	0.47
152_A	547_K	0.705	0.47
161_K	169_R	0.704	0.47
341_I	497_L	0.704	0.47
20_V	255_N	0.704	0.47
147_D	188_A	0.703	0.47
300_A	307_S	0.703	0.47
23_F	99_G	0.703	0.47
239_I	422_S	0.702	0.47
192_I	203_I	0.700	0.46
667_V	675_V	0.700	0.46
168_A	260_I	0.698	0.46
187_D	248_T	0.698	0.46
226_V	253_E	0.698	0.46
580_V	635_L	0.698	0.46
254_G	566_Q	0.697	0.46
144_M	248_T	0.697	0.46
448_S	458_L	0.696	0.46
347_E	435_T	0.696	0.46
417_H	433_I	0.695	0.46
64_L	90_V	0.694	0.46
157_E	519_Q	0.692	0.46
169_R	259_D	0.692	0.46
542_L	546_G	0.691	0.46
487_R	507_E	0.691	0.46
568_T	572_A	0.691	0.46
185_K	503_V	0.691	0.46
279_M	283_I	0.690	0.46
308_K	323_E	0.688	0.45
656_P	661_N	0.688	0.45
239_I	376_A	0.687	0.45
39_A	239_I	0.687	0.45
551_D	556_T	0.687	0.45
164_R	187_D	0.686	0.45
102_V	226_V	0.685	0.45
240_S	440_F	0.684	0.45
386_V	401_L	0.684	0.45
69_R	187_D	0.684	0.45
118_I	125_E	0.684	0.45
339_L	377_L	0.683	0.45
317_D	559_T	0.680	0.45
156_T	657_V	0.679	0.44
188_A	233_Q	0.678	0.44
461_T	471_T	0.678	0.44
349_G	460_Y	0.677	0.44
478_K	581_V	0.677	0.44
71_G	509_T	0.676	0.44
52_A	296_A	0.676	0.44
174_Y	255_N	0.676	0.44
94_G	223_M	0.676	0.44
415_L	531_S	0.674	0.44
49_M	542_L	0.673	0.44
601_G	646_Q	0.672	0.44
278_I	295_L	0.670	0.44
246_V	256_L	0.669	0.44
453_D	457_M	0.668	0.43
158_Q	226_V	0.668	0.43
74_V	564_A	0.668	0.43
36_I	56_S	0.668	0.43
48_N	273_V	0.668	0.43
116_Q	124_A	0.667	0.43
238_L	248_T	0.666	0.43
503_V	544_D	0.666	0.43
20_V	239_I	0.666	0.43
264_L	647_L	0.666	0.43
9_L	168_A	0.665	0.43
25_P	76_T	0.664	0.43
5_D	32_I	0.663	0.43
355_L	361_G	0.663	0.43
116_Q	256_L	0.662	0.43
159_E	213_S	0.662	0.43
209_Q	212_M	0.662	0.43
408_V	476_K	0.661	0.43
480_H	565_K	0.661	0.43
556_T	640_V	0.660	0.43
566_Q	570_Q	0.660	0.43
599_E	675_V	0.660	0.43
117_F	128_S	0.659	0.43
596_Q	669_V	0.658	0.43
221_F	396_P	0.657	0.42
591_I	614_I	0.657	0.42
8_V	260_I	0.656	0.42
74_V	260_I	0.655	0.42
173_F	462_V	0.655	0.42
149_D	154_M	0.655	0.42
201_F	226_V	0.655	0.42
293_G	318_E	0.654	0.42
139_M	149_D	0.654	0.42
491_K	515_V	0.652	0.42
23_F	388_I	0.652	0.42
335_V	386_V	0.652	0.42
167_V	196_M	0.652	0.42
368_I	473_I	0.652	0.42
90_V	231_V	0.651	0.42
65_L	243_T	0.650	0.42
30_I	276_A	0.650	0.42
127_V	155_I	0.650	0.42
531_S	608_P	0.650	0.42
301_F	304_Y	0.649	0.42
623_E	627_L	0.649	0.42
157_E	487_R	0.649	0.42
352_L	386_V	0.648	0.42
118_I	189_I	0.648	0.42
269_K	280_L	0.648	0.42
116_Q	503_V	0.648	0.42
189_I	584_S	0.647	0.41
313_K	532_I	0.646	0.41
558_Y	603_Y	0.646	0.41
268_P	348_F	0.646	0.41
391_N	452_K	0.645	0.41
113_I	116_Q	0.645	0.41
64_L	530_V	0.645	0.41
6_L	9_L	0.645	0.41
315_E	322_E	0.644	0.41
115_I	190_A	0.644	0.41
10_I	449_E	0.644	0.41
29_S	201_F	0.643	0.41
499_E	502_P	0.643	0.41
467_S	489_E	0.641	0.41
312_E	316_V	0.640	0.41
350_Y	392_I	0.640	0.41
424_T	428_D	0.640	0.41
244_G	376_A	0.640	0.41
168_A	534_N	0.639	0.41
155_I	168_A	0.639	0.41
531_S	568_T	0.638	0.41
232_S	287_I	0.637	0.41
60_S	176_A	0.637	0.41
605_S	647_L	0.637	0.41
166_K	169_R	0.637	0.41
618_V	657_V	0.636	0.40
77_T	191_G	0.636	0.40
111_I	121_T	0.636	0.40
138_A	161_K	0.636	0.40
234_I	435_T	0.636	0.40
296_A	629_Q	0.633	0.40
108_V	450_A	0.633	0.40
174_Y	252_S	0.633	0.40
233_Q	236_A	0.631	0.40
125_E	185_K	0.631	0.40
107_V	218_A	0.630	0.40
296_A	300_A	0.630	0.40
226_V	246_V	0.630	0.40
173_F	471_T	0.630	0.40
390_D	471_T	0.630	0.40
14_L	31_L	0.630	0.40
494_I	505_V	0.629	0.40
426_E	430_I	0.628	0.40
239_I	487_R	0.628	0.40
57_I	296_A	0.627	0.40
326_V	401_L	0.627	0.40
530_V	631_T	0.627	0.40
468_V	653_P	0.627	0.40
45_T	120_I	0.626	0.40
112_L	148_A	0.626	0.40
185_K	246_V	0.625	0.39
38_L	659_S	0.625	0.39
347_E	350_Y	0.624	0.39
395_Q	413_L	0.624	0.39
116_Q	238_L	0.622	0.39
301_F	308_K	0.621	0.39
98_V	630_E	0.621	0.39
554_L	558_Y	0.621	0.39
398_E	413_L	0.621	0.39
118_I	273_V	0.620	0.39
75_S	369_V	0.619	0.39
185_K	241_T	0.618	0.39
9_L	32_I	0.618	0.39
418_Y	452_K	0.618	0.39
116_Q	343_P	0.617	0.39
138_A	142_K	0.616	0.39
255_N	264_L	0.616	0.39
189_I	515_V	0.615	0.39
345_E	389_R	0.615	0.39
121_T	233_Q	0.614	0.38
125_E	660_Y	0.614	0.38
10_I	573_K	0.614	0.38
557_E	642_M	0.614	0.38
7_S	239_I	0.613	0.38
88_K	273_V	0.612	0.38
342_D	355_L	0.611	0.38
304_Y	388_I	0.611	0.38
376_A	487_R	0.610	0.38
56_S	425_P	0.610	0.38
191_G	580_V	0.610	0.38
19_L	395_Q	0.609	0.38
513_L	555_L	0.608	0.38
532_I	535_L	0.608	0.38
418_Y	447_I	0.608	0.38
64_L	205_I	0.608	0.38
46_T	196_M	0.608	0.38
252_S	495_D	0.607	0.38
282_G	607_E	0.607	0.38
483_E	537_T	0.605	0.38
45_T	49_M	0.605	0.38
381_L	481_A	0.604	0.38
453_D	565_K	0.604	0.38
226_V	364_L	0.604	0.38
342_D	348_F	0.604	0.38
350_Y	534_N	0.603	0.37
341_I	344_I	0.602	0.37
518_I	562_A	0.602	0.37
243_T	268_P	0.601	0.37
197_I	573_K	0.601	0.37
353_I	388_I	0.600	0.37
386_V	670_Q	0.600	0.37
275_A	580_V	0.599	0.37
67_L	268_P	0.598	0.37
363_D	367_R	0.598	0.37
100_G	223_M	0.598	0.37
409_A	441_G	0.597	0.37
35_N	576_E	0.597	0.37
71_G	172_D	0.596	0.37
484_L	526_L	0.596	0.37
267_Y	547_K	0.596	0.37
346_F	375_L	0.596	0.37
79_S	83_H	0.595	0.37
84_G	116_Q	0.594	0.37
192_I	276_A	0.594	0.37
58_F	109_F	0.593	0.37
214_I	618_V	0.593	0.37
256_L	259_D	0.593	0.37
425_P	428_D	0.593	0.37
398_E	635_L	0.593	0.37
165_E	253_E	0.592	0.36
278_I	299_L	0.592	0.36
48_N	249_R	0.592	0.36
381_L	535_L	0.590	0.36
476_K	654_D	0.590	0.36
147_D	189_I	0.590	0.36
589_K	635_L	0.588	0.36
287_I	346_F	0.588	0.36
359_N	672_I	0.588	0.36
174_Y	246_V	0.587	0.36
42_V	495_D	0.587	0.36
258_H	300_A	0.586	0.36
302_G	306_L	0.586	0.36
211_G	214_I	0.585	0.36
122_K	547_K	0.585	0.36
375_L	477_I	0.584	0.36
191_G	209_Q	0.584	0.36
8_V	256_L	0.584	0.36
101_N	268_P	0.584	0.36
11_S	113_I	0.584	0.36
230_I	240_S	0.583	0.36
86_G	224_L	0.583	0.36
257_G	486_G	0.583	0.36
592_A	654_D	0.583	0.36
79_S	86_G	0.583	0.36
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97_V	383_I	0.582	0.36
637_S	648_L	0.582	0.36
577_V	668_E	0.582	0.36
11_S	64_L	0.581	0.35
399_Y	440_F	0.581	0.35
291_L	294_P	0.581	0.35
271_L	306_L	0.579	0.35
432_G	463_V	0.579	0.35
60_S	210_Q	0.578	0.35
458_L	672_I	0.578	0.35
195_V	244_G	0.578	0.35
248_T	488_Q	0.577	0.35
303_A	307_S	0.577	0.35
10_I	204_V	0.576	0.35
71_G	255_N	0.576	0.35
453_D	493_L	0.576	0.35
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82_S	568_T	0.574	0.35
21_I	647_L	0.574	0.35
232_S	636_C	0.574	0.35
211_G	215_Q	0.573	0.35
23_F	278_I	0.573	0.35
551_D	595_V	0.573	0.35
613_S	663_L	0.572	0.35
555_L	567_I	0.572	0.35
369_V	388_I	0.570	0.35
439_S	460_Y	0.570	0.35
400_R	407_E	0.570	0.35
441_G	468_V	0.570	0.35
31_L	72_L	0.570	0.35
10_I	276_A	0.569	0.34
255_N	258_H	0.569	0.34
189_I	564_A	0.569	0.34
463_V	467_S	0.568	0.34
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120_I	573_K	0.568	0.34
24_P	27_L	0.567	0.34
262_G	318_E	0.567	0.34
135_T	344_I	0.567	0.34
21_I	226_V	0.567	0.34
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360_Q	426_E	0.566	0.34
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302_G	494_I	0.566	0.34
189_I	518_I	0.566	0.34
550_T	659_S	0.566	0.34
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82_S	484_L	0.564	0.34
633_I	668_E	0.564	0.34
125_E	189_I	0.563	0.34
32_I	185_K	0.563	0.34
149_D	163_R	0.562	0.34
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112_L	420_A	0.561	0.34
284_F	287_I	0.561	0.34
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106_L	110_I	0.560	0.34
513_L	669_V	0.560	0.34
582_T	661_N	0.559	0.34
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643_Y	659_S	0.559	0.34
23_F	663_L	0.558	0.34
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81_L	197_I	0.558	0.34
82_S	223_M	0.557	0.33
279_M	431_E	0.557	0.33
225_T	584_S	0.557	0.33
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28_L	72_L	0.557	0.33
23_F	291_L	0.556	0.33
286_P	292_T	0.556	0.33
280_L	675_V	0.556	0.33
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13_V	43_L	0.555	0.33
115_I	365_L	0.555	0.33
221_F	480_H	0.555	0.33
121_T	236_A	0.555	0.33
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508_V	539_F	0.554	0.33
102_V	218_A	0.554	0.33
509_T	513_L	0.554	0.33
387_R	498_K	0.553	0.33
250_A	475_E	0.552	0.33
392_I	467_S	0.552	0.33
33_I	282_G	0.551	0.33
52_A	270_L	0.550	0.33
296_A	589_K	0.550	0.33
352_L	468_V	0.550	0.33
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42_V	419_L	0.549	0.33
11_S	564_A	0.549	0.33
295_L	518_I	0.547	0.33
45_T	92_T	0.546	0.32
275_A	304_Y	0.546	0.32
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124_A	244_G	0.545	0.32
541_T	554_L	0.545	0.32
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316_V	321_E	0.542	0.32
127_V	653_P	0.542	0.32
517_D	552_S	0.542	0.32
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523_A	567_I	0.541	0.32
19_L	604_L	0.541	0.32
558_Y	595_V	0.541	0.32
335_V	382_V	0.540	0.32
116_Q	369_V	0.540	0.32
448_S	675_V	0.540	0.32
173_F	432_G	0.540	0.32
399_Y	411_G	0.540	0.32
32_I	35_N	0.539	0.32
67_L	243_T	0.539	0.32
255_N	277_T	0.539	0.32
349_G	447_I	0.539	0.32
463_V	582_T	0.539	0.32
173_F	181_S	0.539	0.32
541_T	561_Q	0.539	0.32
131_A	259_D	0.539	0.32
274_A	445_K	0.538	0.32
127_V	477_I	0.538	0.32
161_K	370_M	0.538	0.32
314_E	521_V	0.538	0.32
488_Q	558_Y	0.537	0.32
537_T	562_A	0.537	0.32
283_I	675_V	0.537	0.32
190_A	194_I	0.537	0.32
306_L	586_R	0.536	0.32
606_L	610_I	0.535	0.32
353_I	387_R	0.535	0.32
488_Q	515_V	0.533	0.31
312_E	315_E	0.533	0.31
138_A	529_K	0.533	0.31
435_T	485_I	0.533	0.31
353_I	418_Y	0.532	0.31
37_S	284_F	0.532	0.31
370_M	457_M	0.532	0.31
35_N	238_L	0.531	0.31
454_E	458_L	0.531	0.31
363_D	466_A	0.529	0.31
240_S	533_R	0.529	0.31
190_A	224_L	0.529	0.31
295_L	507_E	0.529	0.31
566_Q	584_S	0.528	0.31
568_T	658_L	0.528	0.31
406_N	663_L	0.528	0.31
304_Y	311_K	0.527	0.31
75_S	536_V	0.527	0.31
578_L	663_L	0.526	0.31
342_D	387_R	0.526	0.31
412_E	521_V	0.526	0.31
112_L	287_I	0.525	0.31
266_A	271_L	0.525	0.31
12_V	223_M	0.525	0.31
124_A	483_E	0.525	0.31
308_K	315_E	0.524	0.31
48_N	257_G	0.524	0.31
323_E	499_E	0.523	0.31
419_L	446_W	0.522	0.30
232_S	277_T	0.522	0.30
32_I	116_Q	0.522	0.30
51_E	204_V	0.522	0.30
252_S	259_D	0.522	0.30
637_S	666_N	0.521	0.30
530_V	572_A	0.521	0.30
128_S	247_V	0.520	0.30
322_E	430_I	0.520	0.30
82_S	387_R	0.519	0.30
236_A	468_V	0.519	0.30
44_L	203_I	0.519	0.30
408_V	494_I	0.518	0.30
226_V	535_L	0.518	0.30
83_H	220_H	0.517	0.30
96_F	135_T	0.516	0.30
44_L	643_Y	0.515	0.30
431_E	448_S	0.515	0.30
49_M	643_Y	0.514	0.30
84_G	210_Q	0.514	0.30
515_V	564_A	0.513	0.30
16_V	102_V	0.513	0.30
102_V	277_T	0.513	0.30
73_N	236_A	0.513	0.30
26_W	47_M	0.512	0.30
53_L	268_P	0.512	0.30
413_L	419_L	0.512	0.30
294_P	310_G	0.511	0.30
344_I	484_L	0.511	0.30
9_L	79_S	0.511	0.30
210_Q	226_V	0.511	0.30
364_L	635_L	0.510	0.30
426_E	460_Y	0.510	0.30
169_R	249_R	0.510	0.30
544_D	555_L	0.510	0.30
277_T	547_K	0.510	0.30
100_G	645_K	0.509	0.29
28_L	273_V	0.508	0.29
507_E	528_E	0.508	0.29
671_S	674_V	0.508	0.29
308_K	436_V	0.508	0.29
393_A	437_E	0.507	0.29
169_R	219_S	0.507	0.29
374_Q	612_E	0.507	0.29
18_M	234_I	0.507	0.29
373_R	464_D	0.507	0.29
13_V	278_I	0.506	0.29
354_P	462_V	0.506	0.29
242_A	480_H	0.505	0.29
226_V	486_G	0.505	0.29
386_V	550_T	0.505	0.29
474_T	478_K	0.505	0.29
452_K	456_D	0.505	0.29
53_L	142_K	0.505	0.29
350_Y	357_D	0.504	0.29
226_V	287_I	0.504	0.29
147_D	185_K	0.503	0.29
6_L	315_E	0.502	0.29
110_I	655_L	0.502	0.29
551_D	608_P	0.501	0.29
12_V	580_V	0.500	0.29
19_L	98_V	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mixA	1	0.4623	100	0.606	Contact Map
3a5iA	1	0.5096	100	0.615	Contact Map
3mydA	1	0.5096	100	0.616	Contact Map
2x49A	1	0.4919	100	0.629	Contact Map
4a5pA	3	0.4372	100	0.636	Contact Map
4x86A	1	0.0753	67.1	0.985	Contact Map
1abvA	1	0.1507	51.3	0.986	Contact Map
3bddA	2	0.1965	43	0.987	Contact Map
3f6pA	1	0.1521	25.8	0.988	Contact Map
1p6qA	1	0.1891	25.5	0.988	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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