GREMLIN Database
FLIQ - Flagellar biosynthetic protein FliQ
UniProt: P35535 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 89 (86)
Sequences: 1786 (1139)
Seq/√Len: 122.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_V57_A4.2071.00
27_I57_A3.3041.00
27_I61_A3.2221.00
12_K79_E2.6571.00
61_A65_F2.6441.00
37_I41_T2.5801.00
17_T59_L2.1711.00
20_I69_M2.1411.00
26_A30_L2.1021.00
74_L78_T1.9231.00
78_T82_S1.7031.00
19_M72_T1.6771.00
41_T45_Q1.6671.00
56_V60_L1.6061.00
28_A58_V1.5291.00
83_N86_R1.5171.00
16_V72_T1.4551.00
79_E83_N1.4531.00
40_A43_Q1.4301.00
40_A45_Q1.3441.00
12_K15_Y1.3311.00
46_E49_L1.3101.00
45_Q75_S1.3091.00
77_T81_F1.2951.00
24_L69_M1.2581.00
81_F84_L1.2511.00
8_S11_E1.2130.99
18_L56_V1.2070.99
47_Q50_A1.2020.99
14_V59_L1.2000.99
34_I38_F1.1830.99
50_A53_P1.1580.99
27_I65_F1.1470.99
79_E82_S1.1400.99
36_S58_V1.1260.99
60_L64_F1.1260.99
22_G26_A1.0900.99
29_L53_P1.0770.98
15_Y19_M1.0730.98
24_L62_L1.0680.98
47_Q52_I1.0660.98
23_P54_K1.0580.98
23_P27_I1.0510.98
45_Q49_L1.0460.98
24_L46_E1.0430.98
11_E15_Y1.0420.98
35_V52_I0.9910.97
20_I73_I0.9860.97
28_A50_A0.9760.97
24_L65_F0.9690.97
16_V20_I0.9690.97
27_I31_V0.9660.97
17_T21_S0.9530.97
55_I67_P0.9530.97
38_F44_I0.9300.96
71_S75_S0.9250.96
8_S12_K0.8830.95
25_L36_S0.8820.95
70_L74_L0.8710.95
16_V19_M0.8620.94
28_A48_T0.8570.94
59_L63_I0.8410.93
25_L52_I0.8400.93
77_T80_L0.7880.91
21_S52_I0.7860.91
68_W72_T0.7710.90
12_K76_F0.7610.90
5_F83_N0.7560.89
75_S78_T0.7510.89
10_A18_L0.7490.89
3_S67_P0.7470.89
23_P45_Q0.7470.89
15_Y45_Q0.7300.88
10_A14_V0.7280.87
2_S5_F0.7270.87
75_S79_E0.7240.87
46_E50_A0.7220.87
5_F8_S0.7220.87
13_A40_A0.7200.87
36_S43_Q0.7120.86
4_E8_S0.7040.86
44_I48_T0.6940.85
29_L51_F0.6680.83
26_A62_L0.6620.82
17_T66_G0.6550.81
13_A46_E0.6530.81
43_Q67_P0.6400.80
53_P59_L0.6400.80
2_S63_I0.6400.80
24_L61_A0.6380.80
36_S68_W0.6340.79
81_F85_N0.6330.79
8_S82_S0.6250.78
33_L79_E0.6210.78
60_L78_T0.6200.78
8_S14_V0.6160.77
66_G70_L0.6120.77
10_A59_L0.6100.76
14_V63_I0.6100.76
36_S50_A0.6090.76
23_P76_F0.6070.76
33_L50_A0.6050.76
20_I43_Q0.5710.72
33_L53_P0.5680.71
55_I59_L0.5610.70
62_L65_F0.5600.70
24_L58_V0.5600.70
41_T81_F0.5530.69
33_L37_I0.5500.69
3_S6_V0.5470.68
76_F86_R0.5390.67
7_I11_E0.5370.67
46_E66_G0.5320.66
35_V53_P0.5310.66
15_Y55_I0.5250.65
15_Y25_L0.5220.65
54_K84_L0.5200.65
41_T66_G0.5200.65
8_S83_N0.5170.64
7_I43_Q0.5160.64
65_F69_M0.5160.64
55_I58_V0.5150.64
43_Q77_T0.5120.63
38_F59_L0.5110.63
3_S74_L0.5090.63
33_L44_I0.5060.63
6_V71_S0.5050.62
12_K16_V0.5030.62
16_V76_F0.5000.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pd6A 3 0.3933 18.8 0.909 Contact Map
3tuiA 2 0.9775 4.6 0.931 Contact Map
4ymuD 2 0.9888 3.3 0.936 Contact Map
3rlfF 1 0.9888 2.4 0.94 Contact Map
3mktA 1 0.9888 2.4 0.941 Contact Map
4dxwA 3 0.4831 2.3 0.941 Contact Map
4humA 1 0.9888 2.1 0.942 Contact Map
2fyuK 1 0.5393 1.9 0.944 Contact Map
4ij3C 1 0 1.4 0.948 Contact Map
1rypK 2 0.4944 1.2 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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