RESE - BACSU - GREMLIN Contacts

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RESE - Sensor histidine kinase ResE

UniProt:	P35164	Sequences: MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAENDLTQLANKVAVILENHEDQALARSITWELADNLTSIAIIQDEKNHWYSPNDKNRLSSITVEQIQHDKDLNKALKDHKKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSLLAVKDTTKHTTRYIFLAAGIAIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQLNFHINALNQEKEQLSNILSSMADGVITINIDGTILVTNPPAERFLQAWYYEQNMNIKEGDNLPPEAKELFQNAVSTEKEQMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIAQIIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMFDEDKMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKNIVEAHNGSITVHSRIDKGTTFSFYIPTKR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	589 (551)
Sequences:	6641 (5869)
Seq/√Len:	250.0

ECOLI - ATOS BARA DCUS NARQ NARX DPIB RCSD RCSC TORS ARCB PHOR GLRK CUSS EVGS BAES CREC PHOQ CPXA YEDV QSEC ENVZ RSTB ZRAS NTRB
BACSU - RESE YYCG PHOR MALK DCTS CITS KINC KINE YCLK YVRG KINA YKOH CSSS KIND
HALSA - Q9HQG5 Q9HQ16 O51970 Q9HRE4 Q9HR10 Q9HRG1 Q9HNM2 Q9HQB9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
574_R	577_K	5.010	1.00
519_K	580_T	4.587	1.00
209_D	214_K	4.485	1.00
387_S	408_I	3.944	1.00
225_D	228_G	3.847	1.00
223_T	228_G	3.651	1.00
497_T	521_S	3.555	1.00
467_D	506_S	3.543	1.00
530_L	571_V	3.416	1.00
264_D	353_R	3.251	1.00
485_V	561_I	3.097	1.00
465_D	502_S	3.059	1.00
571_V	581_F	3.005	1.00
358_E	362_D	3.004	1.00
516_I	583_F	2.985	1.00
570_T	582_S	2.921	1.00
504_S	519_K	2.842	1.00
562_V	583_F	2.800	1.00
502_S	521_S	2.796	1.00
506_S	517_D	2.726	1.00
270_N	274_T	2.726	1.00
218_K	235_N	2.711	1.00
485_V	562_V	2.704	1.00
440_I	477_F	2.704	1.00
252_K	256_S	2.704	1.00
559_K	563_E	2.668	1.00
441_N	444_E	2.641	1.00
510_V	515_K	2.640	1.00
477_F	565_H	2.609	1.00
465_D	504_S	2.587	1.00
517_D	580_T	2.530	1.00
506_S	519_K	2.509	1.00
362_D	366_E	2.504	1.00
558_V	569_I	2.490	1.00
359_R	362_D	2.464	1.00
508_H	515_K	2.433	1.00
207_A	237_M	2.374	1.00
561_I	565_H	2.343	1.00
572_H	580_T	2.300	1.00
218_K	242_N	2.289	1.00
467_D	504_S	2.256	1.00
443_N	507_V	2.243	1.00
357_E	360_R	2.226	1.00
497_T	501_G	2.225	1.00
562_V	567_G	2.203	1.00
362_D	365_R	2.188	1.00
391_V	406_Q	2.137	1.00
573_S	577_K	2.131	1.00
573_S	579_T	2.131	1.00
210_L	238_G	2.115	1.00
525_I	529_D	2.105	1.00
517_D	582_S	2.087	1.00
496_H	539_K	2.081	1.00
463_A	502_S	2.081	1.00
515_K	584_Y	2.066	1.00
486_F	516_I	2.051	1.00
477_F	482_M	2.042	1.00
508_H	517_D	2.032	1.00
454_S	458_K	1.983	1.00
363_K	366_E	1.980	1.00
10_K	225_D	1.974	1.00
297_I	301_D	1.967	1.00
203_M	234_F	1.962	1.00
515_K	582_S	1.943	1.00
439_K	476_M	1.925	1.00
520_D	524_G	1.908	1.00
573_S	576_D	1.907	1.00
315_V	318_E	1.904	1.00
281_P	284_R	1.896	1.00
438_E	479_E	1.896	1.00
493_A	503_V	1.893	1.00
84_Q	88_N	1.885	1.00
280_P	284_R	1.866	1.00
513_G	584_Y	1.864	1.00
210_L	237_M	1.849	1.00
265_G	285_F	1.848	1.00
234_F	237_M	1.825	1.00
218_K	238_G	1.819	1.00
189_A	193_S	1.800	1.00
398_E	401_R	1.769	1.00
50_A	54_A	1.763	1.00
152_G	159_S	1.760	1.00
218_K	239_R	1.742	1.00
481_K	484_Q	1.740	1.00
370_A	375_E	1.733	1.00
324_E	327_L	1.723	1.00
267_I	282_A	1.715	1.00
526_P	529_D	1.714	1.00
501_G	521_S	1.699	1.00
288_A	293_Q	1.692	1.00
267_I	275_I	1.685	1.00
526_P	575_I	1.672	1.00
468_I	507_V	1.655	1.00
249_N	252_K	1.653	1.00
80_I	84_Q	1.651	1.00
267_I	350_A	1.639	1.00
527_E	574_R	1.634	1.00
115_K	119_D	1.627	1.00
491_D	495_R	1.619	1.00
497_T	503_V	1.617	1.00
568_S	584_Y	1.609	1.00
207_A	230_L	1.601	1.00
448_K	483_E	1.587	1.00
251_E	254_Q	1.571	1.00
237_M	241_L	1.549	1.00
525_I	533_I	1.538	1.00
391_V	402_K	1.530	1.00
252_K	255_L	1.530	1.00
446_L	507_V	1.528	1.00
530_L	573_S	1.527	1.00
534_F	569_I	1.525	1.00
80_I	93_P	1.522	1.00
88_N	92_S	1.519	1.00
85_D	89_H	1.515	1.00
262_M	266_V	1.515	1.00
485_V	558_V	1.508	1.00
504_S	521_S	1.504	1.00
384_Q	412_S	1.494	1.00
207_A	234_F	1.490	1.00
235_N	238_G	1.483	1.00
481_K	561_I	1.471	1.00
216_D	242_N	1.470	1.00
391_V	409_Y	1.468	1.00
341_A	344_H	1.467	1.00
563_E	568_S	1.463	1.00
533_I	571_V	1.455	1.00
478_D	481_K	1.449	1.00
361_L	365_R	1.447	1.00
140_I	143_V	1.446	1.00
313_N	317_T	1.440	1.00
360_R	364_L	1.440	1.00
120_H	123_V	1.426	1.00
572_H	582_S	1.424	1.00
453_F	487_T	1.419	1.00
486_F	490_I	1.410	1.00
384_Q	413_L	1.409	1.00
532_F	535_E	1.393	1.00
355_M	359_R	1.388	1.00
359_R	365_R	1.384	1.00
298_K	301_D	1.372	1.00
265_G	352_L	1.371	1.00
113_L	117_L	1.367	1.00
486_F	518_I	1.367	1.00
207_A	233_A	1.367	1.00
373_S	378_T	1.360	1.00
76_N	79_S	1.357	1.00
443_N	447_E	1.354	1.00
28_V	32_E	1.343	1.00
238_G	241_L	1.343	1.00
224_Q	228_G	1.337	1.00
80_I	88_N	1.336	1.00
471_T	509_S	1.328	1.00
358_E	365_R	1.306	1.00
204_R	229_E	1.301	1.00
278_T	282_A	1.297	1.00
255_L	259_L	1.295	1.00
309_E	313_N	1.293	1.00
54_A	58_E	1.286	1.00
570_T	584_Y	1.284	1.00
416_G	420_N	1.274	1.00
114_N	118_K	1.273	1.00
441_N	474_E	1.272	1.00
383_L	408_I	1.264	1.00
386_Y	404_I	1.264	1.00
446_L	486_F	1.263	1.00
443_N	468_I	1.257	1.00
6_S	9_G	1.254	1.00
378_T	381_S	1.253	1.00
203_M	231_A	1.252	1.00
482_M	565_H	1.250	1.00
208_Q	229_E	1.248	1.00
495_R	541_D	1.247	1.00
152_G	156_L	1.243	1.00
84_Q	90_W	1.241	1.00
567_G	585_I	1.238	1.00
209_D	217_T	1.233	1.00
81_A	88_N	1.228	1.00
214_K	217_T	1.226	1.00
46_L	50_A	1.222	1.00
534_F	571_V	1.222	1.00
571_V	579_T	1.218	1.00
219_I	235_N	1.215	1.00
412_S	415_M	1.210	1.00
382_M	411_E	1.199	1.00
485_V	565_H	1.199	1.00
203_M	207_A	1.187	1.00
417_R	480_D	1.178	1.00
219_I	231_A	1.177	1.00
375_E	379_P	1.176	1.00
196_V	199_P	1.170	1.00
75_D	79_S	1.170	1.00
37_Y	40_E	1.170	1.00
280_P	283_E	1.168	1.00
256_S	260_S	1.168	1.00
26_L	30_L	1.163	1.00
206_G	234_F	1.162	1.00
562_V	585_I	1.161	1.00
368_F	373_S	1.161	1.00
193_S	197_T	1.157	1.00
411_E	414_R	1.157	1.00
368_F	371_N	1.156	1.00
289_W	293_Q	1.155	1.00
510_V	584_Y	1.151	1.00
206_G	219_I	1.148	1.00
194_S	198_Y	1.146	1.00
82_I	93_P	1.143	1.00
484_Q	561_I	1.135	1.00
383_L	387_S	1.131	1.00
439_K	474_E	1.126	1.00
43_E	47_T	1.124	1.00
390_I	401_R	1.122	1.00
375_E	557_I	1.118	1.00
534_F	581_F	1.117	1.00
441_N	472_E	1.116	1.00
248_L	251_E	1.113	1.00
283_E	290_Y	1.106	1.00
359_R	363_K	1.106	1.00
91_Y	94_N	1.103	1.00
321_Q	324_E	1.101	1.00
486_F	583_F	1.094	1.00
450_I	466_H	1.093	1.00
457_A	503_V	1.086	1.00
361_L	364_L	1.085	1.00
446_L	505_I	1.083	1.00
279_N	282_A	1.081	1.00
457_A	494_L	1.080	1.00
448_K	479_E	1.079	1.00
406_Q	410_D	1.073	1.00
453_F	494_L	1.068	1.00
42_A	46_L	1.063	1.00
312_Q	316_S	1.062	1.00
259_L	279_N	1.061	1.00
449_I	483_E	1.056	1.00
387_S	412_S	1.056	1.00
482_M	583_F	1.052	1.00
242_N	246_N	1.050	1.00
374_H	378_T	1.048	1.00
525_I	579_T	1.044	1.00
527_E	530_L	1.035	1.00
533_I	581_F	1.032	1.00
375_E	378_T	1.029	1.00
375_E	484_Q	1.028	1.00
53_V	56_I	1.025	1.00
47_T	51_N	1.025	1.00
72_E	76_N	1.025	1.00
248_L	252_K	1.024	1.00
507_V	516_I	1.021	1.00
80_I	94_N	1.020	1.00
49_L	53_V	1.019	1.00
529_D	540_A	1.019	1.00
378_T	382_M	1.018	1.00
411_E	423_L	1.017	1.00
385_G	389_A	1.017	1.00
394_I	401_R	1.017	1.00
495_R	539_K	1.017	1.00
243_F	247_A	1.015	1.00
50_A	53_V	1.013	1.00
535_E	538_Y	1.009	1.00
467_D	508_H	1.009	1.00
215_F	241_L	1.008	1.00
244_H	247_A	1.004	1.00
79_S	82_I	1.004	1.00
425_L	429_E	1.000	1.00
8_V	194_S	0.999	1.00
437_Y	476_M	0.995	1.00
423_L	427_R	0.993	1.00
369_I	378_T	0.992	1.00
206_G	217_T	0.988	1.00
447_E	451_R	0.987	1.00
185_T	189_A	0.986	1.00
117_L	120_H	0.985	1.00
283_E	289_W	0.985	1.00
442_V	516_I	0.984	1.00
489_L	558_V	0.983	1.00
490_I	505_I	0.983	1.00
409_Y	413_L	0.975	1.00
152_G	155_F	0.974	1.00
268_T	347_G	0.971	1.00
541_D	549_A	0.970	1.00
449_I	490_I	0.970	1.00
473_E	509_S	0.969	1.00
437_Y	565_H	0.969	1.00
111_K	115_K	0.965	1.00
402_K	406_Q	0.962	1.00
136_N	140_I	0.961	1.00
141_V	144_P	0.959	1.00
422_L	426_A	0.956	1.00
221_I	235_N	0.955	1.00
390_I	405_A	0.950	1.00
371_N	377_R	0.944	1.00
341_A	345_V	0.943	1.00
7_V	196_V	0.942	1.00
230_L	237_M	0.942	1.00
269_I	275_I	0.937	1.00
267_I	279_N	0.935	1.00
372_V	422_L	0.933	1.00
246_N	250_Q	0.932	1.00
80_I	90_W	0.932	1.00
139_L	143_V	0.930	1.00
275_I	282_A	0.930	1.00
469_S	508_H	0.925	1.00
382_M	386_Y	0.922	1.00
386_Y	407_I	0.920	1.00
377_R	415_M	0.920	1.00
134_T	138_R	0.918	1.00
110_D	116_A	0.918	1.00
489_L	581_F	0.918	1.00
496_H	541_D	0.917	1.00
90_W	94_N	0.916	1.00
338_P	345_V	0.915	1.00
529_D	538_Y	0.911	1.00
55_V	58_E	0.909	1.00
329_G	332_W	0.909	1.00
456_V	459_E	0.906	1.00
259_L	277_V	0.904	1.00
247_A	251_E	0.902	1.00
447_E	466_H	0.901	1.00
35_E	39_V	0.900	1.00
445_F	449_I	0.897	1.00
173_Y	176_L	0.897	1.00
489_L	583_F	0.897	1.00
415_M	424_D	0.896	1.00
418_L	429_E	0.896	1.00
381_S	384_Q	0.895	1.00
107_I	110_D	0.892	1.00
154_V	159_S	0.891	1.00
539_K	548_R	0.888	1.00
38_H	41_E	0.888	1.00
370_A	376_L	0.887	1.00
159_S	162_A	0.884	1.00
368_F	372_V	0.882	1.00
489_L	518_I	0.880	1.00
160_L	164_K	0.878	1.00
131_D	134_T	0.878	1.00
376_L	415_M	0.877	1.00
442_V	514_L	0.876	1.00
452_K	487_T	0.876	1.00
171_T	175_F	0.875	1.00
371_N	378_T	0.875	1.00
525_I	555_L	0.874	1.00
85_D	88_N	0.873	1.00
412_S	425_L	0.872	1.00
88_N	93_P	0.872	1.00
258_I	268_T	0.871	1.00
279_N	356_T	0.870	1.00
84_Q	87_K	0.869	0.99
250_Q	254_Q	0.869	0.99
387_S	409_Y	0.869	0.99
110_D	117_L	0.868	0.99
16_L	19_V	0.866	0.99
376_L	418_L	0.862	0.99
485_V	583_F	0.861	0.99
45_D	48_Q	0.861	0.99
373_S	377_R	0.860	0.99
469_S	472_E	0.858	0.99
513_G	568_S	0.856	0.99
231_A	235_N	0.855	0.99
81_A	85_D	0.853	0.99
278_T	283_E	0.852	0.99
110_D	113_L	0.849	0.99
357_E	361_L	0.849	0.99
52_K	56_I	0.849	0.99
367_D	371_N	0.847	0.99
370_A	373_S	0.847	0.99
461_N	499_A	0.847	0.99
143_V	146_E	0.846	0.99
323_I	327_L	0.845	0.99
30_L	34_I	0.844	0.99
352_L	356_T	0.844	0.99
371_N	536_R	0.844	0.99
324_E	359_R	0.841	0.99
39_V	42_A	0.839	0.99
262_M	265_G	0.838	0.99
497_T	539_K	0.838	0.99
204_R	208_Q	0.834	0.99
26_L	29_L	0.834	0.99
562_V	569_I	0.829	0.99
358_E	361_L	0.828	0.99
479_E	483_E	0.826	0.99
49_L	54_A	0.824	0.99
39_V	43_E	0.822	0.99
403_E	451_R	0.821	0.99
12_W	16_L	0.820	0.99
423_L	429_E	0.820	0.99
213_G	237_M	0.819	0.99
112_D	120_H	0.819	0.99
278_T	294_N	0.818	0.99
368_F	423_L	0.818	0.99
369_I	372_V	0.815	0.99
401_R	405_A	0.813	0.99
570_T	583_F	0.813	0.99
376_L	379_P	0.812	0.99
376_L	419_V	0.811	0.99
204_R	233_A	0.811	0.99
37_Y	41_E	0.811	0.99
387_S	405_A	0.811	0.99
269_I	350_A	0.810	0.99
483_E	487_T	0.810	0.99
144_P	152_G	0.809	0.99
382_M	407_I	0.807	0.99
53_V	60_H	0.806	0.99
208_Q	212_K	0.804	0.99
172_R	176_L	0.804	0.99
153_M	157_S	0.803	0.99
116_A	119_D	0.802	0.99
373_S	496_H	0.800	0.99
89_H	92_S	0.800	0.99
496_H	540_A	0.800	0.99
275_I	278_T	0.799	0.99
475_F	585_I	0.799	0.99
199_P	226_E	0.795	0.99
259_L	262_M	0.795	0.99
331_S	334_L	0.794	0.99
27_T	31_L	0.789	0.99
376_L	386_Y	0.788	0.99
113_L	120_H	0.788	0.99
525_I	581_F	0.788	0.99
532_F	538_Y	0.787	0.99
418_L	423_L	0.785	0.99
472_E	507_V	0.783	0.99
495_R	540_A	0.782	0.99
457_A	464_L	0.782	0.99
309_E	312_Q	0.780	0.99
411_E	422_L	0.780	0.99
445_F	477_F	0.779	0.99
330_R	334_L	0.779	0.99
307_A	314_A	0.779	0.99
421_D	551_T	0.774	0.99
41_E	45_D	0.774	0.99
384_Q	416_G	0.774	0.99
360_R	363_K	0.773	0.99
417_R	421_D	0.772	0.99
255_L	258_I	0.770	0.99
403_E	406_Q	0.769	0.99
259_L	268_T	0.768	0.99
525_I	530_L	0.767	0.99
46_L	49_L	0.767	0.99
368_F	378_T	0.766	0.99
48_Q	52_K	0.765	0.99
245_I	249_N	0.761	0.99
84_Q	92_S	0.759	0.99
57_L	60_H	0.759	0.99
251_E	255_L	0.758	0.99
279_N	354_D	0.758	0.99
80_I	83_I	0.757	0.99
369_I	381_S	0.757	0.99
87_K	91_Y	0.753	0.99
265_G	279_N	0.751	0.99
378_T	496_H	0.750	0.99
407_I	411_E	0.750	0.99
322_M	326_T	0.750	0.99
444_E	448_K	0.749	0.99
22_V	26_L	0.748	0.98
142_G	145_Y	0.747	0.98
496_H	548_R	0.746	0.98
50_A	156_L	0.746	0.98
43_E	46_L	0.746	0.98
384_Q	387_S	0.745	0.98
523_S	579_T	0.745	0.98
106_Q	110_D	0.745	0.98
134_T	140_I	0.744	0.98
254_Q	277_V	0.743	0.98
335_L	338_P	0.742	0.98
374_H	377_R	0.739	0.98
350_A	354_D	0.739	0.98
415_M	423_L	0.738	0.98
146_E	149_G	0.737	0.98
45_D	49_L	0.736	0.98
82_I	90_W	0.734	0.98
310_L	313_N	0.734	0.98
73_L	76_N	0.734	0.98
241_L	244_H	0.733	0.98
450_I	454_S	0.733	0.98
435_L	481_K	0.733	0.98
199_P	234_F	0.733	0.98
307_A	311_F	0.732	0.98
327_L	330_R	0.732	0.98
371_N	541_D	0.731	0.98
34_I	41_E	0.731	0.98
553_L	557_I	0.730	0.98
109_H	112_D	0.728	0.98
73_L	79_S	0.726	0.98
168_K	171_T	0.726	0.98
404_I	408_I	0.726	0.98
377_R	416_G	0.724	0.98
359_R	364_L	0.724	0.98
87_K	90_W	0.721	0.98
496_H	523_S	0.721	0.98
378_T	385_G	0.721	0.98
373_S	495_R	0.719	0.98
455_G	459_E	0.715	0.98
268_T	277_V	0.715	0.98
311_F	314_A	0.714	0.98
424_D	429_E	0.713	0.98
446_L	466_H	0.712	0.98
259_L	266_V	0.712	0.98
279_N	283_E	0.711	0.98
422_L	427_R	0.711	0.98
482_M	486_F	0.711	0.98
481_K	485_V	0.710	0.98
156_L	159_S	0.709	0.98
347_G	350_A	0.708	0.98
464_L	503_V	0.708	0.98
379_P	415_M	0.708	0.98
311_F	315_V	0.707	0.98
236_Q	240_Q	0.707	0.98
249_N	253_E	0.705	0.98
109_H	113_L	0.705	0.98
401_R	404_I	0.703	0.98
340_Y	343_S	0.703	0.98
49_L	52_K	0.702	0.98
207_A	211_A	0.702	0.98
155_F	159_S	0.702	0.98
244_H	248_L	0.700	0.98
329_G	333_V	0.699	0.98
297_I	302_N	0.699	0.98
44_N	48_Q	0.698	0.98
396_S	401_R	0.697	0.98
8_V	12_W	0.696	0.98
367_D	375_E	0.695	0.98
497_T	523_S	0.695	0.98
412_S	416_G	0.692	0.97
356_T	359_R	0.691	0.97
523_S	548_R	0.690	0.97
307_A	318_E	0.690	0.97
144_P	148_D	0.690	0.97
228_G	231_A	0.689	0.97
383_L	412_S	0.689	0.97
240_Q	243_F	0.688	0.97
444_E	479_E	0.687	0.97
437_Y	477_F	0.686	0.97
116_A	120_H	0.686	0.97
425_L	428_M	0.683	0.97
259_L	263_A	0.683	0.97
462_I	503_V	0.682	0.97
399_E	403_E	0.682	0.97
536_R	541_D	0.681	0.97
280_P	287_Q	0.681	0.97
328_Q	331_S	0.680	0.97
374_H	379_P	0.679	0.97
450_I	464_L	0.679	0.97
139_L	142_G	0.678	0.97
42_A	45_D	0.677	0.97
268_T	349_V	0.677	0.97
414_R	418_L	0.675	0.97
322_M	327_L	0.674	0.97
307_A	310_L	0.674	0.97
114_N	117_L	0.673	0.97
421_D	426_A	0.673	0.97
371_N	375_E	0.672	0.97
335_L	339_L	0.672	0.97
46_L	158_Q	0.671	0.97
41_E	44_N	0.671	0.97
435_L	565_H	0.669	0.97
88_N	94_N	0.668	0.97
279_N	286_L	0.668	0.97
134_T	137_E	0.666	0.97
22_V	25_I	0.666	0.97
268_T	279_N	0.666	0.97
300_G	304_P	0.664	0.97
523_S	573_S	0.664	0.97
289_W	292_E	0.663	0.97
247_A	250_Q	0.663	0.97
19_V	22_V	0.662	0.97
83_I	93_P	0.661	0.97
266_V	279_N	0.660	0.97
424_D	431_G	0.660	0.97
370_A	379_P	0.659	0.97
81_A	91_Y	0.659	0.97
80_I	92_S	0.659	0.97
398_E	402_K	0.658	0.97
382_M	390_I	0.657	0.97
369_I	373_S	0.656	0.97
378_T	384_Q	0.656	0.97
395_A	401_R	0.656	0.97
48_Q	51_N	0.656	0.97
415_M	425_L	0.656	0.97
81_A	84_Q	0.655	0.97
382_M	425_L	0.654	0.96
371_N	425_L	0.654	0.96
207_A	210_L	0.653	0.96
418_L	426_A	0.653	0.96
191_F	195_R	0.653	0.96
138_R	141_V	0.653	0.96
495_R	548_R	0.651	0.96
33_F	37_Y	0.651	0.96
484_Q	557_I	0.648	0.96
55_V	59_N	0.647	0.96
117_L	121_K	0.647	0.96
369_I	380_I	0.646	0.96
90_W	93_P	0.646	0.96
351_V	354_D	0.644	0.96
368_F	377_R	0.643	0.96
387_S	391_V	0.643	0.96
140_I	157_S	0.642	0.96
473_E	514_L	0.641	0.96
138_R	142_G	0.641	0.96
230_L	234_F	0.641	0.96
202_K	220_P	0.641	0.96
370_A	418_L	0.639	0.96
453_F	490_I	0.638	0.96
462_I	521_S	0.638	0.96
536_R	539_K	0.636	0.96
85_D	92_S	0.635	0.96
258_I	279_N	0.635	0.96
369_I	496_H	0.634	0.96
311_F	318_E	0.633	0.96
40_E	43_E	0.630	0.96
152_G	157_S	0.629	0.96
440_I	482_M	0.629	0.96
51_N	55_V	0.628	0.96
110_D	120_H	0.628	0.96
226_E	230_L	0.627	0.96
53_V	57_L	0.627	0.96
36_N	39_V	0.625	0.95
508_H	511_K	0.624	0.95
234_F	238_G	0.621	0.95
490_I	503_V	0.621	0.95
453_F	456_V	0.620	0.95
38_H	49_L	0.620	0.95
149_G	154_V	0.620	0.95
51_N	54_A	0.619	0.95
75_D	80_I	0.619	0.95
435_L	564_A	0.619	0.95
24_F	28_V	0.617	0.95
293_Q	296_N	0.617	0.95
79_S	89_H	0.614	0.95
141_V	146_E	0.610	0.95
338_P	347_G	0.610	0.95
435_L	478_D	0.609	0.95
8_V	201_R	0.609	0.95
274_T	298_K	0.609	0.95
141_V	145_Y	0.608	0.95
380_I	389_A	0.608	0.95
370_A	377_R	0.607	0.95
33_F	38_H	0.606	0.95
536_R	540_A	0.606	0.95
114_N	120_H	0.606	0.95
310_L	315_V	0.605	0.95
282_A	286_L	0.605	0.95
377_R	382_M	0.605	0.95
56_I	60_H	0.603	0.95
35_E	38_H	0.602	0.94
423_L	426_A	0.602	0.94
386_Y	539_K	0.601	0.94
368_F	376_L	0.600	0.94
84_Q	94_N	0.600	0.94
32_E	35_E	0.599	0.94
284_R	287_Q	0.598	0.94
377_R	411_E	0.596	0.94
44_N	47_T	0.595	0.94
283_E	294_N	0.595	0.94
310_L	314_A	0.595	0.94
76_N	80_I	0.595	0.94
404_I	536_R	0.594	0.94
462_I	494_L	0.593	0.94
381_S	385_G	0.592	0.94
358_E	364_L	0.592	0.94
374_H	382_M	0.592	0.94
299_E	302_N	0.591	0.94
140_I	146_E	0.590	0.94
372_V	376_L	0.590	0.94
358_E	366_E	0.590	0.94
199_P	203_M	0.590	0.94
349_V	352_L	0.590	0.94
371_N	386_Y	0.590	0.94
15_I	22_V	0.589	0.94
208_Q	236_Q	0.587	0.94
537_F	553_L	0.586	0.94
344_H	347_G	0.586	0.94
481_K	558_V	0.586	0.94
314_A	317_T	0.584	0.94
274_T	296_N	0.578	0.93
285_F	332_W	0.577	0.93
73_L	78_T	0.576	0.93
114_N	119_D	0.576	0.93
517_D	572_H	0.575	0.93
336_M	348_A	0.575	0.93
386_Y	411_E	0.574	0.93
377_R	386_Y	0.572	0.93
440_I	445_F	0.572	0.93
377_R	420_N	0.572	0.93
77_L	80_I	0.572	0.93
109_H	116_A	0.571	0.93
475_F	514_L	0.570	0.93
525_I	573_S	0.570	0.93
258_I	261_S	0.569	0.93
441_N	445_F	0.568	0.93
168_K	172_R	0.568	0.93
84_Q	93_P	0.567	0.93
82_I	87_K	0.565	0.92
153_M	159_S	0.565	0.92
254_Q	268_T	0.564	0.92
288_A	294_N	0.564	0.92
415_M	428_M	0.564	0.92
449_I	453_F	0.564	0.92
107_I	112_D	0.563	0.92
290_Y	295_M	0.563	0.92
140_I	145_Y	0.563	0.92
81_A	87_K	0.562	0.92
49_L	57_L	0.561	0.92
152_G	160_L	0.560	0.92
199_P	225_D	0.559	0.92
422_L	429_E	0.559	0.92
560_N	563_E	0.559	0.92
336_M	339_L	0.557	0.92
441_N	447_E	0.556	0.92
482_M	585_I	0.556	0.92
110_D	114_N	0.556	0.92
415_M	419_V	0.555	0.92
47_T	50_A	0.555	0.92
113_L	116_A	0.554	0.92
78_T	94_N	0.554	0.92
408_I	411_E	0.553	0.92
258_I	265_G	0.553	0.92
283_E	286_L	0.553	0.92
254_Q	258_I	0.553	0.92
308_K	315_V	0.553	0.92
56_I	59_N	0.552	0.92
29_L	32_E	0.551	0.91
382_M	389_A	0.550	0.91
275_I	279_N	0.549	0.91
418_L	425_L	0.549	0.91
371_N	376_L	0.549	0.91
151_K	154_V	0.549	0.91
369_I	376_L	0.549	0.91
371_N	389_A	0.548	0.91
226_E	237_M	0.547	0.91
397_S	401_R	0.547	0.91
369_I	377_R	0.547	0.91
447_E	450_I	0.546	0.91
541_D	548_R	0.546	0.91
368_F	539_K	0.546	0.91
373_S	379_P	0.545	0.91
399_E	402_K	0.544	0.91
491_D	551_T	0.544	0.91
369_I	375_E	0.544	0.91
10_K	195_R	0.543	0.91
287_Q	294_N	0.543	0.91
388_E	392_D	0.543	0.91
251_E	256_S	0.542	0.91
424_D	481_K	0.542	0.91
380_I	412_S	0.540	0.91
393_D	401_R	0.539	0.91
374_H	488_N	0.539	0.91
233_A	237_M	0.538	0.90
380_I	386_Y	0.538	0.90
116_A	122_K	0.538	0.90
260_S	280_P	0.537	0.90
527_E	531_P	0.537	0.90
408_I	412_S	0.536	0.90
117_L	122_K	0.535	0.90
330_R	333_V	0.534	0.90
458_K	461_N	0.534	0.90
384_Q	388_E	0.534	0.90
377_R	484_Q	0.534	0.90
371_N	415_M	0.530	0.90
385_G	390_I	0.530	0.90
215_F	235_N	0.530	0.90
573_S	580_T	0.529	0.90
143_V	147_K	0.528	0.90
81_A	92_S	0.528	0.90
488_N	551_T	0.527	0.90
505_I	516_I	0.527	0.90
146_E	152_G	0.527	0.90
373_S	497_T	0.526	0.89
54_A	57_L	0.526	0.89
437_Y	566_N	0.525	0.89
117_L	123_V	0.525	0.89
378_T	557_I	0.524	0.89
529_D	541_D	0.524	0.89
112_D	115_K	0.523	0.89
371_N	559_K	0.523	0.89
222_L	228_G	0.522	0.89
134_T	141_V	0.521	0.89
259_L	265_G	0.521	0.89
264_D	281_P	0.521	0.89
529_D	532_F	0.520	0.89
372_V	382_M	0.520	0.89
410_D	448_K	0.520	0.89
412_S	423_L	0.520	0.89
536_R	560_N	0.519	0.89
405_A	423_L	0.519	0.89
135_D	143_V	0.519	0.89
340_Y	345_V	0.518	0.89
90_W	95_D	0.518	0.89
381_S	416_G	0.518	0.89
380_I	383_L	0.518	0.89
372_V	377_R	0.518	0.89
144_P	153_M	0.518	0.89
115_K	118_K	0.517	0.89
377_R	495_R	0.517	0.89
276_L	347_G	0.516	0.89
405_A	412_S	0.516	0.89
372_V	381_S	0.516	0.89
526_P	540_A	0.516	0.89
509_S	514_L	0.516	0.89
526_P	533_I	0.516	0.89
352_L	355_M	0.515	0.88
169_H	172_R	0.515	0.88
435_L	561_I	0.515	0.88
481_K	564_A	0.514	0.88
273_G	279_N	0.514	0.88
46_L	54_A	0.514	0.88
151_K	159_S	0.514	0.88
283_E	287_Q	0.513	0.88
152_G	158_Q	0.513	0.88
207_A	213_G	0.512	0.88
42_A	50_A	0.511	0.88
321_Q	325_M	0.511	0.88
337_S	349_V	0.511	0.88
419_V	425_L	0.507	0.88
381_S	411_E	0.507	0.88
496_H	538_Y	0.506	0.88
375_E	418_L	0.506	0.88
371_N	388_E	0.506	0.88
226_E	234_F	0.506	0.88
136_N	139_L	0.505	0.88
269_I	348_A	0.504	0.87
411_E	421_D	0.504	0.87
386_Y	408_I	0.504	0.87
223_T	235_N	0.503	0.87
373_S	423_L	0.503	0.87
347_G	352_L	0.502	0.87
136_N	142_G	0.501	0.87
444_E	447_E	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.6604	100	0.352	Contact Map
3a0rA	2	0.5382	100	0.481	Contact Map
4gczA	2	0.5722	100	0.483	Contact Map
4bixA	2	0.3871	100	0.559	Contact Map
4r3aA	1	0.5076	100	0.577	Contact Map
4ctiA	2	0.3871	100	0.59	Contact Map
3jz3A	2	0.275	100	0.61	Contact Map
4q20A	2	0.3922	100	0.611	Contact Map
2c2aA	2	0.3888	100	0.612	Contact Map
4mpcA	2	0.5161	100	0.615	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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