GREMLIN Database
RESE - Sensor histidine kinase ResE
UniProt: P35164 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 589 (551)
Sequences: 6641 (5869)
Seq/√Len: 250.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
574_R577_K5.0101.00
519_K580_T4.5871.00
209_D214_K4.4851.00
387_S408_I3.9441.00
225_D228_G3.8471.00
223_T228_G3.6511.00
497_T521_S3.5551.00
467_D506_S3.5431.00
530_L571_V3.4161.00
264_D353_R3.2511.00
485_V561_I3.0971.00
465_D502_S3.0591.00
571_V581_F3.0051.00
358_E362_D3.0041.00
516_I583_F2.9851.00
570_T582_S2.9211.00
504_S519_K2.8421.00
562_V583_F2.8001.00
502_S521_S2.7961.00
506_S517_D2.7261.00
270_N274_T2.7261.00
218_K235_N2.7111.00
485_V562_V2.7041.00
440_I477_F2.7041.00
252_K256_S2.7041.00
559_K563_E2.6681.00
441_N444_E2.6411.00
510_V515_K2.6401.00
477_F565_H2.6091.00
465_D504_S2.5871.00
517_D580_T2.5301.00
506_S519_K2.5091.00
362_D366_E2.5041.00
558_V569_I2.4901.00
359_R362_D2.4641.00
508_H515_K2.4331.00
207_A237_M2.3741.00
561_I565_H2.3431.00
572_H580_T2.3001.00
218_K242_N2.2891.00
467_D504_S2.2561.00
443_N507_V2.2431.00
357_E360_R2.2261.00
497_T501_G2.2251.00
562_V567_G2.2031.00
362_D365_R2.1881.00
391_V406_Q2.1371.00
573_S577_K2.1311.00
573_S579_T2.1311.00
210_L238_G2.1151.00
525_I529_D2.1051.00
517_D582_S2.0871.00
496_H539_K2.0811.00
463_A502_S2.0811.00
515_K584_Y2.0661.00
486_F516_I2.0511.00
477_F482_M2.0421.00
508_H517_D2.0321.00
454_S458_K1.9831.00
363_K366_E1.9801.00
10_K225_D1.9741.00
297_I301_D1.9671.00
203_M234_F1.9621.00
515_K582_S1.9431.00
439_K476_M1.9251.00
520_D524_G1.9081.00
573_S576_D1.9071.00
315_V318_E1.9041.00
281_P284_R1.8961.00
438_E479_E1.8961.00
493_A503_V1.8931.00
84_Q88_N1.8851.00
280_P284_R1.8661.00
513_G584_Y1.8641.00
210_L237_M1.8491.00
265_G285_F1.8481.00
234_F237_M1.8251.00
218_K238_G1.8191.00
189_A193_S1.8001.00
398_E401_R1.7691.00
50_A54_A1.7631.00
152_G159_S1.7601.00
218_K239_R1.7421.00
481_K484_Q1.7401.00
370_A375_E1.7331.00
324_E327_L1.7231.00
267_I282_A1.7151.00
526_P529_D1.7141.00
501_G521_S1.6991.00
288_A293_Q1.6921.00
267_I275_I1.6851.00
526_P575_I1.6721.00
468_I507_V1.6551.00
249_N252_K1.6531.00
80_I84_Q1.6511.00
267_I350_A1.6391.00
527_E574_R1.6341.00
115_K119_D1.6271.00
491_D495_R1.6191.00
497_T503_V1.6171.00
568_S584_Y1.6091.00
207_A230_L1.6011.00
448_K483_E1.5871.00
251_E254_Q1.5711.00
237_M241_L1.5491.00
525_I533_I1.5381.00
391_V402_K1.5301.00
252_K255_L1.5301.00
446_L507_V1.5281.00
530_L573_S1.5271.00
534_F569_I1.5251.00
80_I93_P1.5221.00
88_N92_S1.5191.00
85_D89_H1.5151.00
262_M266_V1.5151.00
485_V558_V1.5081.00
504_S521_S1.5041.00
384_Q412_S1.4941.00
207_A234_F1.4901.00
235_N238_G1.4831.00
481_K561_I1.4711.00
216_D242_N1.4701.00
391_V409_Y1.4681.00
341_A344_H1.4671.00
563_E568_S1.4631.00
533_I571_V1.4551.00
478_D481_K1.4491.00
361_L365_R1.4471.00
140_I143_V1.4461.00
313_N317_T1.4401.00
360_R364_L1.4401.00
120_H123_V1.4261.00
572_H582_S1.4241.00
453_F487_T1.4191.00
486_F490_I1.4101.00
384_Q413_L1.4091.00
532_F535_E1.3931.00
355_M359_R1.3881.00
359_R365_R1.3841.00
298_K301_D1.3721.00
265_G352_L1.3711.00
113_L117_L1.3671.00
486_F518_I1.3671.00
207_A233_A1.3671.00
373_S378_T1.3601.00
76_N79_S1.3571.00
443_N447_E1.3541.00
28_V32_E1.3431.00
238_G241_L1.3431.00
224_Q228_G1.3371.00
80_I88_N1.3361.00
471_T509_S1.3281.00
358_E365_R1.3061.00
204_R229_E1.3011.00
278_T282_A1.2971.00
255_L259_L1.2951.00
309_E313_N1.2931.00
54_A58_E1.2861.00
570_T584_Y1.2841.00
416_G420_N1.2741.00
114_N118_K1.2731.00
441_N474_E1.2721.00
383_L408_I1.2641.00
386_Y404_I1.2641.00
446_L486_F1.2631.00
443_N468_I1.2571.00
6_S9_G1.2541.00
378_T381_S1.2531.00
203_M231_A1.2521.00
482_M565_H1.2501.00
208_Q229_E1.2481.00
495_R541_D1.2471.00
152_G156_L1.2431.00
84_Q90_W1.2411.00
567_G585_I1.2381.00
209_D217_T1.2331.00
81_A88_N1.2281.00
214_K217_T1.2261.00
46_L50_A1.2221.00
534_F571_V1.2221.00
571_V579_T1.2181.00
219_I235_N1.2151.00
412_S415_M1.2101.00
382_M411_E1.1991.00
485_V565_H1.1991.00
203_M207_A1.1871.00
417_R480_D1.1781.00
219_I231_A1.1771.00
375_E379_P1.1761.00
196_V199_P1.1701.00
75_D79_S1.1701.00
37_Y40_E1.1701.00
280_P283_E1.1681.00
256_S260_S1.1681.00
26_L30_L1.1631.00
206_G234_F1.1621.00
562_V585_I1.1611.00
368_F373_S1.1611.00
193_S197_T1.1571.00
411_E414_R1.1571.00
368_F371_N1.1561.00
289_W293_Q1.1551.00
510_V584_Y1.1511.00
206_G219_I1.1481.00
194_S198_Y1.1461.00
82_I93_P1.1431.00
484_Q561_I1.1351.00
383_L387_S1.1311.00
439_K474_E1.1261.00
43_E47_T1.1241.00
390_I401_R1.1221.00
375_E557_I1.1181.00
534_F581_F1.1171.00
441_N472_E1.1161.00
248_L251_E1.1131.00
283_E290_Y1.1061.00
359_R363_K1.1061.00
91_Y94_N1.1031.00
321_Q324_E1.1011.00
486_F583_F1.0941.00
450_I466_H1.0931.00
457_A503_V1.0861.00
361_L364_L1.0851.00
446_L505_I1.0831.00
279_N282_A1.0811.00
457_A494_L1.0801.00
448_K479_E1.0791.00
406_Q410_D1.0731.00
453_F494_L1.0681.00
42_A46_L1.0631.00
312_Q316_S1.0621.00
259_L279_N1.0611.00
449_I483_E1.0561.00
387_S412_S1.0561.00
482_M583_F1.0521.00
242_N246_N1.0501.00
374_H378_T1.0481.00
525_I579_T1.0441.00
527_E530_L1.0351.00
533_I581_F1.0321.00
375_E378_T1.0291.00
375_E484_Q1.0281.00
53_V56_I1.0251.00
47_T51_N1.0251.00
72_E76_N1.0251.00
248_L252_K1.0241.00
507_V516_I1.0211.00
80_I94_N1.0201.00
49_L53_V1.0191.00
529_D540_A1.0191.00
378_T382_M1.0181.00
411_E423_L1.0171.00
385_G389_A1.0171.00
394_I401_R1.0171.00
495_R539_K1.0171.00
243_F247_A1.0151.00
50_A53_V1.0131.00
535_E538_Y1.0091.00
467_D508_H1.0091.00
215_F241_L1.0081.00
244_H247_A1.0041.00
79_S82_I1.0041.00
425_L429_E1.0001.00
8_V194_S0.9991.00
437_Y476_M0.9951.00
423_L427_R0.9931.00
369_I378_T0.9921.00
206_G217_T0.9881.00
447_E451_R0.9871.00
185_T189_A0.9861.00
117_L120_H0.9851.00
283_E289_W0.9851.00
442_V516_I0.9841.00
489_L558_V0.9831.00
490_I505_I0.9831.00
409_Y413_L0.9751.00
152_G155_F0.9741.00
268_T347_G0.9711.00
541_D549_A0.9701.00
449_I490_I0.9701.00
473_E509_S0.9691.00
437_Y565_H0.9691.00
111_K115_K0.9651.00
402_K406_Q0.9621.00
136_N140_I0.9611.00
141_V144_P0.9591.00
422_L426_A0.9561.00
221_I235_N0.9551.00
390_I405_A0.9501.00
371_N377_R0.9441.00
341_A345_V0.9431.00
7_V196_V0.9421.00
230_L237_M0.9421.00
269_I275_I0.9371.00
267_I279_N0.9351.00
372_V422_L0.9331.00
246_N250_Q0.9321.00
80_I90_W0.9321.00
139_L143_V0.9301.00
275_I282_A0.9301.00
469_S508_H0.9251.00
382_M386_Y0.9221.00
386_Y407_I0.9201.00
377_R415_M0.9201.00
134_T138_R0.9181.00
110_D116_A0.9181.00
489_L581_F0.9181.00
496_H541_D0.9171.00
90_W94_N0.9161.00
338_P345_V0.9151.00
529_D538_Y0.9111.00
55_V58_E0.9091.00
329_G332_W0.9091.00
456_V459_E0.9061.00
259_L277_V0.9041.00
247_A251_E0.9021.00
447_E466_H0.9011.00
35_E39_V0.9001.00
445_F449_I0.8971.00
173_Y176_L0.8971.00
489_L583_F0.8971.00
415_M424_D0.8961.00
418_L429_E0.8961.00
381_S384_Q0.8951.00
107_I110_D0.8921.00
154_V159_S0.8911.00
539_K548_R0.8881.00
38_H41_E0.8881.00
370_A376_L0.8871.00
159_S162_A0.8841.00
368_F372_V0.8821.00
489_L518_I0.8801.00
160_L164_K0.8781.00
131_D134_T0.8781.00
376_L415_M0.8771.00
442_V514_L0.8761.00
452_K487_T0.8761.00
171_T175_F0.8751.00
371_N378_T0.8751.00
525_I555_L0.8741.00
85_D88_N0.8731.00
412_S425_L0.8721.00
88_N93_P0.8721.00
258_I268_T0.8711.00
279_N356_T0.8701.00
84_Q87_K0.8690.99
250_Q254_Q0.8690.99
387_S409_Y0.8690.99
110_D117_L0.8680.99
16_L19_V0.8660.99
376_L418_L0.8620.99
485_V583_F0.8610.99
45_D48_Q0.8610.99
373_S377_R0.8600.99
469_S472_E0.8580.99
513_G568_S0.8560.99
231_A235_N0.8550.99
81_A85_D0.8530.99
278_T283_E0.8520.99
110_D113_L0.8490.99
357_E361_L0.8490.99
52_K56_I0.8490.99
367_D371_N0.8470.99
370_A373_S0.8470.99
461_N499_A0.8470.99
143_V146_E0.8460.99
323_I327_L0.8450.99
30_L34_I0.8440.99
352_L356_T0.8440.99
371_N536_R0.8440.99
324_E359_R0.8410.99
39_V42_A0.8390.99
262_M265_G0.8380.99
497_T539_K0.8380.99
204_R208_Q0.8340.99
26_L29_L0.8340.99
562_V569_I0.8290.99
358_E361_L0.8280.99
479_E483_E0.8260.99
49_L54_A0.8240.99
39_V43_E0.8220.99
403_E451_R0.8210.99
12_W16_L0.8200.99
423_L429_E0.8200.99
213_G237_M0.8190.99
112_D120_H0.8190.99
278_T294_N0.8180.99
368_F423_L0.8180.99
369_I372_V0.8150.99
401_R405_A0.8130.99
570_T583_F0.8130.99
376_L379_P0.8120.99
376_L419_V0.8110.99
204_R233_A0.8110.99
37_Y41_E0.8110.99
387_S405_A0.8110.99
269_I350_A0.8100.99
483_E487_T0.8100.99
144_P152_G0.8090.99
382_M407_I0.8070.99
53_V60_H0.8060.99
208_Q212_K0.8040.99
172_R176_L0.8040.99
153_M157_S0.8030.99
116_A119_D0.8020.99
373_S496_H0.8000.99
89_H92_S0.8000.99
496_H540_A0.8000.99
275_I278_T0.7990.99
475_F585_I0.7990.99
199_P226_E0.7950.99
259_L262_M0.7950.99
331_S334_L0.7940.99
27_T31_L0.7890.99
376_L386_Y0.7880.99
113_L120_H0.7880.99
525_I581_F0.7880.99
532_F538_Y0.7870.99
418_L423_L0.7850.99
472_E507_V0.7830.99
495_R540_A0.7820.99
457_A464_L0.7820.99
309_E312_Q0.7800.99
411_E422_L0.7800.99
445_F477_F0.7790.99
330_R334_L0.7790.99
307_A314_A0.7790.99
421_D551_T0.7740.99
41_E45_D0.7740.99
384_Q416_G0.7740.99
360_R363_K0.7730.99
417_R421_D0.7720.99
255_L258_I0.7700.99
403_E406_Q0.7690.99
259_L268_T0.7680.99
525_I530_L0.7670.99
46_L49_L0.7670.99
368_F378_T0.7660.99
48_Q52_K0.7650.99
245_I249_N0.7610.99
84_Q92_S0.7590.99
57_L60_H0.7590.99
251_E255_L0.7580.99
279_N354_D0.7580.99
80_I83_I0.7570.99
369_I381_S0.7570.99
87_K91_Y0.7530.99
265_G279_N0.7510.99
378_T496_H0.7500.99
407_I411_E0.7500.99
322_M326_T0.7500.99
444_E448_K0.7490.99
22_V26_L0.7480.98
142_G145_Y0.7470.98
496_H548_R0.7460.98
50_A156_L0.7460.98
43_E46_L0.7460.98
384_Q387_S0.7450.98
523_S579_T0.7450.98
106_Q110_D0.7450.98
134_T140_I0.7440.98
254_Q277_V0.7430.98
335_L338_P0.7420.98
374_H377_R0.7390.98
350_A354_D0.7390.98
415_M423_L0.7380.98
146_E149_G0.7370.98
45_D49_L0.7360.98
82_I90_W0.7340.98
310_L313_N0.7340.98
73_L76_N0.7340.98
241_L244_H0.7330.98
450_I454_S0.7330.98
435_L481_K0.7330.98
199_P234_F0.7330.98
307_A311_F0.7320.98
327_L330_R0.7320.98
371_N541_D0.7310.98
34_I41_E0.7310.98
553_L557_I0.7300.98
109_H112_D0.7280.98
73_L79_S0.7260.98
168_K171_T0.7260.98
404_I408_I0.7260.98
377_R416_G0.7240.98
359_R364_L0.7240.98
87_K90_W0.7210.98
496_H523_S0.7210.98
378_T385_G0.7210.98
373_S495_R0.7190.98
455_G459_E0.7150.98
268_T277_V0.7150.98
311_F314_A0.7140.98
424_D429_E0.7130.98
446_L466_H0.7120.98
259_L266_V0.7120.98
279_N283_E0.7110.98
422_L427_R0.7110.98
482_M486_F0.7110.98
481_K485_V0.7100.98
156_L159_S0.7090.98
347_G350_A0.7080.98
464_L503_V0.7080.98
379_P415_M0.7080.98
311_F315_V0.7070.98
236_Q240_Q0.7070.98
249_N253_E0.7050.98
109_H113_L0.7050.98
401_R404_I0.7030.98
340_Y343_S0.7030.98
49_L52_K0.7020.98
207_A211_A0.7020.98
155_F159_S0.7020.98
244_H248_L0.7000.98
329_G333_V0.6990.98
297_I302_N0.6990.98
44_N48_Q0.6980.98
396_S401_R0.6970.98
8_V12_W0.6960.98
367_D375_E0.6950.98
497_T523_S0.6950.98
412_S416_G0.6920.97
356_T359_R0.6910.97
523_S548_R0.6900.97
307_A318_E0.6900.97
144_P148_D0.6900.97
228_G231_A0.6890.97
383_L412_S0.6890.97
240_Q243_F0.6880.97
444_E479_E0.6870.97
437_Y477_F0.6860.97
116_A120_H0.6860.97
425_L428_M0.6830.97
259_L263_A0.6830.97
462_I503_V0.6820.97
399_E403_E0.6820.97
536_R541_D0.6810.97
280_P287_Q0.6810.97
328_Q331_S0.6800.97
374_H379_P0.6790.97
450_I464_L0.6790.97
139_L142_G0.6780.97
42_A45_D0.6770.97
268_T349_V0.6770.97
414_R418_L0.6750.97
322_M327_L0.6740.97
307_A310_L0.6740.97
114_N117_L0.6730.97
421_D426_A0.6730.97
371_N375_E0.6720.97
335_L339_L0.6720.97
46_L158_Q0.6710.97
41_E44_N0.6710.97
435_L565_H0.6690.97
88_N94_N0.6680.97
279_N286_L0.6680.97
134_T137_E0.6660.97
22_V25_I0.6660.97
268_T279_N0.6660.97
300_G304_P0.6640.97
523_S573_S0.6640.97
289_W292_E0.6630.97
247_A250_Q0.6630.97
19_V22_V0.6620.97
83_I93_P0.6610.97
266_V279_N0.6600.97
424_D431_G0.6600.97
370_A379_P0.6590.97
81_A91_Y0.6590.97
80_I92_S0.6590.97
398_E402_K0.6580.97
382_M390_I0.6570.97
369_I373_S0.6560.97
378_T384_Q0.6560.97
395_A401_R0.6560.97
48_Q51_N0.6560.97
415_M425_L0.6560.97
81_A84_Q0.6550.97
382_M425_L0.6540.96
371_N425_L0.6540.96
207_A210_L0.6530.96
418_L426_A0.6530.96
191_F195_R0.6530.96
138_R141_V0.6530.96
495_R548_R0.6510.96
33_F37_Y0.6510.96
484_Q557_I0.6480.96
55_V59_N0.6470.96
117_L121_K0.6470.96
369_I380_I0.6460.96
90_W93_P0.6460.96
351_V354_D0.6440.96
368_F377_R0.6430.96
387_S391_V0.6430.96
140_I157_S0.6420.96
473_E514_L0.6410.96
138_R142_G0.6410.96
230_L234_F0.6410.96
202_K220_P0.6410.96
370_A418_L0.6390.96
453_F490_I0.6380.96
462_I521_S0.6380.96
536_R539_K0.6360.96
85_D92_S0.6350.96
258_I279_N0.6350.96
369_I496_H0.6340.96
311_F318_E0.6330.96
40_E43_E0.6300.96
152_G157_S0.6290.96
440_I482_M0.6290.96
51_N55_V0.6280.96
110_D120_H0.6280.96
226_E230_L0.6270.96
53_V57_L0.6270.96
36_N39_V0.6250.95
508_H511_K0.6240.95
234_F238_G0.6210.95
490_I503_V0.6210.95
453_F456_V0.6200.95
38_H49_L0.6200.95
149_G154_V0.6200.95
51_N54_A0.6190.95
75_D80_I0.6190.95
435_L564_A0.6190.95
24_F28_V0.6170.95
293_Q296_N0.6170.95
79_S89_H0.6140.95
141_V146_E0.6100.95
338_P347_G0.6100.95
435_L478_D0.6090.95
8_V201_R0.6090.95
274_T298_K0.6090.95
141_V145_Y0.6080.95
380_I389_A0.6080.95
370_A377_R0.6070.95
33_F38_H0.6060.95
536_R540_A0.6060.95
114_N120_H0.6060.95
310_L315_V0.6050.95
282_A286_L0.6050.95
377_R382_M0.6050.95
56_I60_H0.6030.95
35_E38_H0.6020.94
423_L426_A0.6020.94
386_Y539_K0.6010.94
368_F376_L0.6000.94
84_Q94_N0.6000.94
32_E35_E0.5990.94
284_R287_Q0.5980.94
377_R411_E0.5960.94
44_N47_T0.5950.94
283_E294_N0.5950.94
310_L314_A0.5950.94
76_N80_I0.5950.94
404_I536_R0.5940.94
462_I494_L0.5930.94
381_S385_G0.5920.94
358_E364_L0.5920.94
374_H382_M0.5920.94
299_E302_N0.5910.94
140_I146_E0.5900.94
372_V376_L0.5900.94
358_E366_E0.5900.94
199_P203_M0.5900.94
349_V352_L0.5900.94
371_N386_Y0.5900.94
15_I22_V0.5890.94
208_Q236_Q0.5870.94
537_F553_L0.5860.94
344_H347_G0.5860.94
481_K558_V0.5860.94
314_A317_T0.5840.94
274_T296_N0.5780.93
285_F332_W0.5770.93
73_L78_T0.5760.93
114_N119_D0.5760.93
517_D572_H0.5750.93
336_M348_A0.5750.93
386_Y411_E0.5740.93
377_R386_Y0.5720.93
440_I445_F0.5720.93
377_R420_N0.5720.93
77_L80_I0.5720.93
109_H116_A0.5710.93
475_F514_L0.5700.93
525_I573_S0.5700.93
258_I261_S0.5690.93
441_N445_F0.5680.93
168_K172_R0.5680.93
84_Q93_P0.5670.93
82_I87_K0.5650.92
153_M159_S0.5650.92
254_Q268_T0.5640.92
288_A294_N0.5640.92
415_M428_M0.5640.92
449_I453_F0.5640.92
107_I112_D0.5630.92
290_Y295_M0.5630.92
140_I145_Y0.5630.92
81_A87_K0.5620.92
49_L57_L0.5610.92
152_G160_L0.5600.92
199_P225_D0.5590.92
422_L429_E0.5590.92
560_N563_E0.5590.92
336_M339_L0.5570.92
441_N447_E0.5560.92
482_M585_I0.5560.92
110_D114_N0.5560.92
415_M419_V0.5550.92
47_T50_A0.5550.92
113_L116_A0.5540.92
78_T94_N0.5540.92
408_I411_E0.5530.92
258_I265_G0.5530.92
283_E286_L0.5530.92
254_Q258_I0.5530.92
308_K315_V0.5530.92
56_I59_N0.5520.92
29_L32_E0.5510.91
382_M389_A0.5500.91
275_I279_N0.5490.91
418_L425_L0.5490.91
371_N376_L0.5490.91
151_K154_V0.5490.91
369_I376_L0.5490.91
371_N389_A0.5480.91
226_E237_M0.5470.91
397_S401_R0.5470.91
369_I377_R0.5470.91
447_E450_I0.5460.91
541_D548_R0.5460.91
368_F539_K0.5460.91
373_S379_P0.5450.91
399_E402_K0.5440.91
491_D551_T0.5440.91
369_I375_E0.5440.91
10_K195_R0.5430.91
287_Q294_N0.5430.91
388_E392_D0.5430.91
251_E256_S0.5420.91
424_D481_K0.5420.91
380_I412_S0.5400.91
393_D401_R0.5390.91
374_H488_N0.5390.91
233_A237_M0.5380.90
380_I386_Y0.5380.90
116_A122_K0.5380.90
260_S280_P0.5370.90
527_E531_P0.5370.90
408_I412_S0.5360.90
117_L122_K0.5350.90
330_R333_V0.5340.90
458_K461_N0.5340.90
384_Q388_E0.5340.90
377_R484_Q0.5340.90
371_N415_M0.5300.90
385_G390_I0.5300.90
215_F235_N0.5300.90
573_S580_T0.5290.90
143_V147_K0.5280.90
81_A92_S0.5280.90
488_N551_T0.5270.90
505_I516_I0.5270.90
146_E152_G0.5270.90
373_S497_T0.5260.89
54_A57_L0.5260.89
437_Y566_N0.5250.89
117_L123_V0.5250.89
378_T557_I0.5240.89
529_D541_D0.5240.89
112_D115_K0.5230.89
371_N559_K0.5230.89
222_L228_G0.5220.89
134_T141_V0.5210.89
259_L265_G0.5210.89
264_D281_P0.5210.89
529_D532_F0.5200.89
372_V382_M0.5200.89
410_D448_K0.5200.89
412_S423_L0.5200.89
536_R560_N0.5190.89
405_A423_L0.5190.89
135_D143_V0.5190.89
340_Y345_V0.5180.89
90_W95_D0.5180.89
381_S416_G0.5180.89
380_I383_L0.5180.89
372_V377_R0.5180.89
144_P153_M0.5180.89
115_K118_K0.5170.89
377_R495_R0.5170.89
276_L347_G0.5160.89
405_A412_S0.5160.89
372_V381_S0.5160.89
526_P540_A0.5160.89
509_S514_L0.5160.89
526_P533_I0.5160.89
352_L355_M0.5150.88
169_H172_R0.5150.88
435_L561_I0.5150.88
481_K564_A0.5140.88
273_G279_N0.5140.88
46_L54_A0.5140.88
151_K159_S0.5140.88
283_E287_Q0.5130.88
152_G158_Q0.5130.88
207_A213_G0.5120.88
42_A50_A0.5110.88
321_Q325_M0.5110.88
337_S349_V0.5110.88
419_V425_L0.5070.88
381_S411_E0.5070.88
496_H538_Y0.5060.88
375_E418_L0.5060.88
371_N388_E0.5060.88
226_E234_F0.5060.88
136_N139_L0.5050.88
269_I348_A0.5040.87
411_E421_D0.5040.87
386_Y408_I0.5040.87
223_T235_N0.5030.87
373_S423_L0.5030.87
347_G352_L0.5020.87
136_N142_G0.5010.87
444_E447_E0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.6604 100 0.352 Contact Map
3a0rA 2 0.5382 100 0.481 Contact Map
4gczA 2 0.5722 100 0.483 Contact Map
4bixA 2 0.3871 100 0.559 Contact Map
4r3aA 1 0.5076 100 0.577 Contact Map
4ctiA 2 0.3871 100 0.59 Contact Map
3jz3A 2 0.275 100 0.61 Contact Map
4q20A 2 0.3922 100 0.611 Contact Map
2c2aA 2 0.3888 100 0.612 Contact Map
4mpcA 2 0.5161 100 0.615 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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