SERA - BACSU - GREMLIN Contacts

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SERA - D-3-phosphoglycerate dehydrogenase

UniProt:	P35136	Sequences: MFRVLVSDKMSNDGLQPLIESDFIEIVQKNVADAEDELHTFDALLVRSATKVTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVGSELYGKTLGIVGLGRIGSEIAQRARAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLPVMSAINLPAMTKDEFAKIKPYHQIAGKIGSLVSQCMKEPVQDVAIQYEGTIAKLETSFITKALLSGFLKPRVDSTVNEVNAGGVAKERGISFSEKISSSESGYDNCISVKVTGDRSTFTVTATYIPHFGERIVEINGFNIDFYPTGHLVYIQHQDTTGVIGRVGRILGDNDINIATMQVGRKEKGGEAIMMLSFDRHLEDKIVKELTNVPDIVSVKLIDLP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	525 (520)
Sequences:	1486 (815)
Seq/√Len:	35.7

ECOLI - SERA
BACSU - SERA
HALSA - Q9HMR0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
234_D	237_A	5.772	1.00
222_V	247_V	4.967	1.00
220_K	246_H	4.897	1.00
57_F	66_V	4.663	1.00
212_K	240_E	4.605	1.00
111_M	195_I	4.086	1.00
110_L	249_G	3.983	1.00
46_V	76_I	3.982	1.00
187_E	217_K	3.890	1.00
211_N	214_T	3.860	1.00
44_L	52_V	3.857	1.00
182_N	192_S	3.634	1.00
208_G	234_D	3.392	1.00
25_E	41_F	3.375	1.00
239_L	268_H	3.311	1.00
185_T	188_E	3.245	1.00
243_E	268_H	3.193	1.00
198_V	232_I	3.129	1.00
473_D	509_E	3.109	1.00
242_L	270_L	2.960	1.00
330_G	369_S	2.906	1.00
239_L	243_E	2.889	1.00
141_L	157_A	2.812	1.00
196_I	222_V	2.801	1.00
31_V	55_D	2.794	1.00
221_G	247_V	2.671	1.00
498_F	502_L	2.613	1.00
57_F	86_V	2.605	1.00
30_N	33_D	2.567	1.00
367_L	413_V	2.500	1.00
202_L	207_K	2.498	1.00
215_I	246_H	2.438	1.00
208_G	256_E	2.402	1.00
223_R	248_A	2.393	1.00
66_V	86_V	2.388	1.00
127_N	130_A	2.370	1.00
347_V	371_F	2.366	1.00
465_G	468_G	2.365	1.00
184_R	189_V	2.358	1.00
215_I	218_T	2.333	0.99
195_I	223_R	2.319	0.99
12_N	16_Q	2.309	0.99
118_N	122_K	2.261	0.99
190_L	218_T	2.228	0.99
346_D	416_T	2.209	0.99
218_T	222_V	2.197	0.99
479_A	485_R	2.166	0.99
35_E	55_D	2.159	0.99
16_Q	20_E	2.129	0.99
191_E	217_K	2.125	0.99
104_F	160_F	2.108	0.99
104_F	157_A	2.095	0.99
35_E	59_K	2.077	0.99
54_E	58_N	2.077	0.99
438_E	441_G	2.069	0.99
424_V	427_T	2.061	0.99
141_L	162_M	2.036	0.99
35_E	56_L	2.026	0.98
110_L	223_R	2.022	0.98
54_E	83_K	2.008	0.98
121_V	273_A	1.984	0.98
465_G	472_G	1.978	0.98
210_L	215_I	1.943	0.98
483_V	494_M	1.925	0.98
216_A	244_N	1.919	0.98
410_C	437_V	1.914	0.98
368_L	396_F	1.872	0.97
11_S	286_L	1.865	0.97
31_V	35_E	1.856	0.97
38_L	61_T	1.853	0.97
268_H	271_V	1.843	0.97
42_D	62_S	1.842	0.97
37_E	41_F	1.830	0.97
103_T	227_C	1.827	0.97
142_G	189_V	1.826	0.97
218_T	246_H	1.825	0.97
336_V	415_V	1.812	0.97
110_L	251_A	1.809	0.97
508_K	512_N	1.805	0.97
208_G	211_N	1.798	0.97
243_E	270_L	1.798	0.97
163_T	182_N	1.791	0.97
137_Y	161_G	1.788	0.97
190_L	214_T	1.772	0.96
31_V	53_T	1.757	0.96
122_K	267_D	1.751	0.96
422_F	440_N	1.730	0.96
108_S	160_F	1.730	0.96
242_L	268_H	1.686	0.95
38_L	41_F	1.679	0.95
508_K	511_T	1.662	0.95
212_K	237_A	1.654	0.95
43_A	296_V	1.654	0.95
243_E	267_D	1.653	0.95
102_H	106_M	1.625	0.94
120_S	131_Y	1.611	0.94
165_H	184_R	1.607	0.94
211_N	237_A	1.605	0.94
255_F	273_A	1.588	0.93
211_N	234_D	1.587	0.93
110_L	272_I	1.586	0.93
105_A	114_I	1.571	0.93
176_A	183_S	1.569	0.93
239_L	252_L	1.563	0.93
190_L	210_L	1.557	0.93
119_I	123_S	1.545	0.93
67_G	292_V	1.542	0.92
474_N	509_E	1.518	0.92
140_T	163_T	1.514	0.92
221_G	244_N	1.512	0.92
134_S	223_R	1.507	0.92
241_A	247_V	1.506	0.92
33_D	36_D	1.506	0.92
134_S	195_I	1.505	0.91
236_A	264_K	1.501	0.91
40_T	62_S	1.492	0.91
61_T	84_H	1.473	0.91
142_G	193_A	1.472	0.91
454_Y	495_M	1.464	0.90
52_V	66_V	1.462	0.90
21_S	301_K	1.462	0.90
165_H	192_S	1.433	0.89
115_P	272_I	1.433	0.89
83_K	391_E	1.427	0.89
504_D	508_K	1.422	0.89
440_N	456_Q	1.419	0.89
120_S	125_E	1.417	0.89
329_A	411_I	1.416	0.89
106_M	114_I	1.413	0.89
144_V	198_V	1.398	0.88
210_L	218_T	1.396	0.88
213_E	217_K	1.390	0.88
9_K	129_T	1.372	0.87
223_R	249_G	1.358	0.87
236_A	240_E	1.358	0.87
351_Y	364_T	1.351	0.86
102_H	114_I	1.351	0.86
215_I	241_A	1.350	0.86
233_I	252_L	1.332	0.86
216_A	246_H	1.331	0.85
481_M	494_M	1.327	0.85
221_G	245_G	1.319	0.85
485_R	492_A	1.315	0.85
299_F	305_V	1.313	0.85
173_E	177_K	1.312	0.85
73_V	76_I	1.306	0.84
427_T	430_P	1.304	0.84
143_I	154_A	1.300	0.84
298_Q	303_L	1.297	0.84
424_V	428_Y	1.292	0.84
459_D	492_A	1.290	0.84
7_S	44_L	1.283	0.83
94_G	288_V	1.279	0.83
53_T	56_L	1.270	0.83
240_E	243_E	1.269	0.83
239_L	264_K	1.263	0.82
102_H	105_A	1.252	0.82
242_L	271_V	1.247	0.81
341_K	520_K	1.243	0.81
106_M	227_C	1.243	0.81
27_V	37_E	1.239	0.81
3_R	25_E	1.238	0.81
12_N	19_I	1.234	0.81
462_G	468_G	1.233	0.81
6_V	14_G	1.232	0.81
231_G	235_E	1.219	0.80
348_A	397_S	1.216	0.80
351_Y	398_E	1.214	0.80
27_V	41_F	1.205	0.79
58_N	80_E	1.204	0.79
485_R	489_G	1.204	0.79
351_Y	360_T	1.200	0.79
9_K	49_A	1.199	0.79
299_F	302_G	1.190	0.78
425_T	428_Y	1.176	0.77
102_H	274_T	1.174	0.77
29_K	33_D	1.174	0.77
329_A	367_L	1.160	0.76
212_K	216_A	1.159	0.76
368_L	386_G	1.157	0.76
347_V	368_L	1.156	0.76
121_V	266_V	1.147	0.76
32_A	55_D	1.140	0.75
252_L	271_V	1.140	0.75
485_R	499_D	1.137	0.75
186_F	190_L	1.137	0.75
204_K	207_K	1.135	0.75
184_R	192_S	1.135	0.75
345_Q	418_D	1.130	0.75
221_G	246_H	1.128	0.74
239_L	267_D	1.126	0.74
212_K	244_N	1.120	0.74
209_L	252_L	1.117	0.74
94_G	289_A	1.114	0.73
348_A	414_K	1.106	0.73
486_K	491_E	1.099	0.72
297_L	301_K	1.097	0.72
470_I	510_L	1.096	0.72
60_M	84_H	1.087	0.72
410_C	425_T	1.086	0.72
342_E	419_R	1.084	0.71
236_A	263_N	1.079	0.71
210_L	224_L	1.070	0.70
44_L	56_L	1.069	0.70
54_E	80_E	1.067	0.70
144_V	210_L	1.063	0.70
332_I	436_I	1.060	0.70
224_L	233_I	1.055	0.69
503_E	506_I	1.055	0.69
89_I	494_M	1.049	0.69
453_V	498_F	1.049	0.69
451_H	521_L	1.047	0.69
507_V	519_V	1.044	0.68
140_T	165_H	1.043	0.68
188_E	192_S	1.042	0.68
469_R	473_D	1.042	0.68
58_N	84_H	1.042	0.68
236_A	256_E	1.037	0.68
436_I	448_P	1.037	0.68
39_H	59_K	1.030	0.67
13_D	286_L	1.029	0.67
457_H	494_M	1.025	0.67
37_E	40_T	1.024	0.67
25_E	28_Q	1.022	0.67
459_D	462_G	1.021	0.67
39_H	61_T	1.021	0.67
46_V	52_V	1.019	0.67
166_V	181_V	1.019	0.67
152_E	155_Q	1.017	0.66
214_T	217_K	1.015	0.66
479_A	499_D	1.012	0.66
466_R	515_D	1.012	0.66
257_V	261_V	1.008	0.66
157_A	162_M	1.008	0.66
476_I	506_I	1.005	0.65
239_L	242_L	1.005	0.65
251_A	272_I	1.000	0.65
222_V	246_H	1.000	0.65
350_Q	414_K	0.999	0.65
209_L	232_I	0.998	0.65
342_E	418_D	0.994	0.65
218_T	247_V	0.991	0.64
89_I	100_A	0.991	0.64
510_L	519_V	0.986	0.64
6_V	24_I	0.982	0.64
57_F	84_H	0.979	0.63
143_I	197_T	0.978	0.63
479_A	489_G	0.975	0.63
176_A	181_V	0.974	0.63
215_I	224_L	0.972	0.63
158_R	164_V	0.969	0.63
295_E	457_H	0.965	0.62
151_S	175_R	0.963	0.62
7_S	52_V	0.962	0.62
426_A	430_P	0.960	0.62
296_V	300_A	0.958	0.62
210_L	214_T	0.958	0.62
218_T	244_N	0.957	0.62
456_Q	491_E	0.956	0.62
121_V	255_F	0.954	0.61
332_I	335_L	0.950	0.61
425_T	438_E	0.947	0.61
98_S	128_R	0.946	0.61
8_D	289_A	0.945	0.61
346_D	395_S	0.944	0.61
189_V	193_A	0.944	0.61
170_F	209_L	0.942	0.60
105_A	108_S	0.939	0.60
153_I	197_T	0.937	0.60
457_H	483_V	0.937	0.60
389_A	396_F	0.935	0.60
27_V	33_D	0.935	0.60
146_L	181_V	0.935	0.60
116_Q	272_I	0.933	0.60
329_A	363_I	0.932	0.60
213_E	237_A	0.928	0.59
240_E	244_N	0.926	0.59
76_I	148_R	0.923	0.59
120_S	127_N	0.921	0.59
187_E	213_E	0.921	0.59
98_S	160_F	0.920	0.59
95_N	99_T	0.919	0.58
420_S	427_T	0.914	0.58
414_K	421_T	0.914	0.58
509_E	512_N	0.913	0.58
260_P	266_V	0.913	0.58
474_N	506_I	0.910	0.58
3_R	40_T	0.910	0.58
7_S	46_V	0.908	0.58
117_A	131_Y	0.907	0.57
349_I	367_L	0.901	0.57
504_D	521_L	0.901	0.57
152_E	156_R	0.899	0.57
232_I	481_M	0.895	0.56
369_S	382_E	0.893	0.56
187_E	191_E	0.893	0.56
463_V	480_T	0.887	0.56
440_N	467_V	0.887	0.56
156_R	160_F	0.885	0.56
111_M	134_S	0.885	0.56
305_V	311_L	0.884	0.56
186_F	210_L	0.884	0.56
224_L	247_V	0.882	0.55
502_L	506_I	0.878	0.55
193_A	196_I	0.877	0.55
8_D	105_A	0.875	0.55
190_L	222_V	0.873	0.55
25_E	37_E	0.872	0.54
416_T	421_T	0.872	0.54
241_A	246_H	0.871	0.54
186_F	189_V	0.871	0.54
110_L	248_A	0.871	0.54
18_L	296_V	0.871	0.54
89_I	292_V	0.869	0.54
144_V	189_V	0.868	0.54
46_V	79_D	0.865	0.54
158_R	180_G	0.865	0.54
165_H	189_V	0.858	0.53
23_F	301_K	0.856	0.53
25_E	29_K	0.853	0.53
49_A	149_I	0.853	0.53
14_G	18_L	0.853	0.53
57_F	80_E	0.852	0.53
105_A	277_L	0.851	0.53
82_T	280_S	0.849	0.52
376_V	392_R	0.847	0.52
6_V	15_L	0.847	0.52
41_F	61_T	0.847	0.52
124_R	267_D	0.845	0.52
479_A	492_A	0.843	0.52
106_M	115_P	0.838	0.52
244_N	504_D	0.835	0.51
13_D	16_Q	0.834	0.51
466_R	513_V	0.833	0.51
102_H	251_A	0.833	0.51
328_I	332_I	0.831	0.51
135_E	287_N	0.827	0.51
97_I	137_Y	0.824	0.50
136_L	160_F	0.824	0.50
369_S	373_K	0.823	0.50
462_G	492_A	0.822	0.50
45_L	296_V	0.821	0.50
213_E	236_A	0.815	0.50
26_I	325_Y	0.814	0.49
213_E	216_A	0.814	0.49
279_A	285_Q	0.812	0.49
412_S	425_T	0.812	0.49
182_N	188_E	0.812	0.49
331_K	450_G	0.811	0.49
334_S	338_Q	0.806	0.49
71_V	93_N	0.806	0.49
10_M	159_A	0.803	0.49
327_Q	330_G	0.803	0.49
38_L	60_M	0.802	0.48
71_V	91_A	0.802	0.48
332_I	413_V	0.801	0.48
146_L	171_L	0.798	0.48
164_V	181_V	0.796	0.48
18_L	45_L	0.796	0.48
21_S	297_L	0.795	0.48
25_E	38_L	0.795	0.48
116_Q	131_Y	0.794	0.48
266_V	273_A	0.793	0.48
151_S	181_V	0.792	0.48
32_A	39_H	0.791	0.47
146_L	166_V	0.791	0.47
86_V	395_S	0.788	0.47
468_G	472_G	0.788	0.47
467_V	494_M	0.785	0.47
152_E	202_L	0.785	0.47
261_V	266_V	0.784	0.47
380_V	388_V	0.783	0.47
47_R	68_R	0.781	0.47
187_E	214_T	0.777	0.46
136_L	195_I	0.777	0.46
118_N	272_I	0.775	0.46
38_L	52_V	0.772	0.46
100_A	434_E	0.771	0.46
106_M	251_A	0.770	0.46
239_L	270_L	0.769	0.46
116_Q	251_A	0.765	0.45
288_V	457_H	0.765	0.45
3_R	33_D	0.762	0.45
459_D	485_R	0.762	0.45
66_V	76_I	0.760	0.45
231_G	279_A	0.759	0.45
424_V	436_I	0.755	0.44
230_G	259_P	0.754	0.44
257_V	260_P	0.751	0.44
122_K	273_A	0.750	0.44
89_I	307_S	0.746	0.44
505_K	509_E	0.745	0.44
155_Q	161_G	0.745	0.44
89_I	295_E	0.744	0.43
456_Q	518_S	0.744	0.43
238_L	247_V	0.743	0.43
24_I	27_V	0.742	0.43
46_V	82_T	0.741	0.43
67_G	440_N	0.741	0.43
46_V	280_S	0.741	0.43
220_K	244_N	0.740	0.43
120_S	130_A	0.739	0.43
116_Q	120_S	0.738	0.43
500_R	510_L	0.737	0.43
89_I	296_V	0.737	0.43
130_A	269_P	0.736	0.43
47_R	72_G	0.736	0.43
464_I	481_M	0.735	0.43
99_T	104_F	0.735	0.43
396_F	469_R	0.735	0.43
477_N	499_D	0.732	0.42
5_L	41_F	0.731	0.42
65_I	299_F	0.731	0.42
445_D	494_M	0.729	0.42
65_I	89_I	0.729	0.42
454_Y	522_I	0.727	0.42
104_F	159_A	0.725	0.42
65_I	302_G	0.724	0.42
222_V	242_L	0.724	0.42
181_V	233_I	0.724	0.42
98_S	155_Q	0.724	0.42
52_V	109_S	0.722	0.42
128_R	302_G	0.721	0.41
99_T	255_F	0.721	0.41
54_E	344_V	0.718	0.41
109_S	115_P	0.718	0.41
233_I	247_V	0.713	0.41
277_L	280_S	0.712	0.41
272_I	431_H	0.710	0.41
109_S	264_K	0.710	0.41
118_N	273_A	0.709	0.40
196_I	324_P	0.707	0.40
57_F	61_T	0.707	0.40
116_Q	269_P	0.705	0.40
195_I	225_I	0.703	0.40
10_M	286_L	0.701	0.40
106_M	200_T	0.700	0.40
10_M	45_L	0.699	0.40
95_N	229_R	0.699	0.40
270_L	473_D	0.699	0.40
196_I	217_K	0.698	0.40
144_V	209_L	0.697	0.39
483_V	492_A	0.697	0.39
72_G	254_V	0.696	0.39
106_M	272_I	0.695	0.39
368_L	389_A	0.693	0.39
336_V	340_M	0.692	0.39
14_G	17_P	0.690	0.39
325_Y	409_N	0.689	0.39
444_I	473_D	0.689	0.39
298_Q	306_M	0.689	0.39
347_V	413_V	0.689	0.39
24_I	28_Q	0.688	0.39
459_D	479_A	0.687	0.39
122_K	510_L	0.686	0.39
102_H	107_I	0.686	0.39
491_E	517_V	0.684	0.38
337_S	371_F	0.684	0.38
428_Y	431_H	0.684	0.38
457_H	481_M	0.684	0.38
464_I	483_V	0.684	0.38
161_G	295_E	0.683	0.38
5_L	81_A	0.683	0.38
420_S	429_I	0.683	0.38
459_D	477_N	0.683	0.38
40_T	61_T	0.682	0.38
184_R	193_A	0.678	0.38
89_I	305_V	0.677	0.38
94_G	287_N	0.677	0.38
55_D	58_N	0.676	0.38
91_A	291_Q	0.674	0.38
327_Q	331_K	0.674	0.38
354_T	409_N	0.674	0.38
66_V	380_V	0.673	0.38
215_I	220_K	0.673	0.38
174_E	251_A	0.672	0.37
128_R	446_F	0.668	0.37
16_Q	19_I	0.668	0.37
82_T	483_V	0.667	0.37
367_L	371_F	0.666	0.37
274_T	288_V	0.666	0.37
35_E	57_F	0.666	0.37
366_A	507_V	0.665	0.37
212_K	246_H	0.665	0.37
11_S	176_A	0.664	0.37
120_S	123_S	0.663	0.37
143_I	200_T	0.663	0.37
79_D	83_K	0.661	0.37
173_E	183_S	0.660	0.36
295_E	307_S	0.659	0.36
215_I	247_V	0.659	0.36
442_F	481_M	0.659	0.36
471_L	506_I	0.658	0.36
38_L	56_L	0.658	0.36
332_I	446_F	0.657	0.36
114_I	131_Y	0.657	0.36
98_S	146_L	0.657	0.36
38_L	44_L	0.655	0.36
196_I	247_V	0.655	0.36
99_T	128_R	0.655	0.36
345_Q	416_T	0.654	0.36
7_S	24_I	0.653	0.36
221_G	242_L	0.653	0.36
64_K	495_M	0.650	0.36
445_D	448_P	0.650	0.36
17_P	295_E	0.649	0.36
435_R	479_A	0.648	0.35
4_V	333_G	0.648	0.35
121_V	261_V	0.648	0.35
73_V	78_I	0.648	0.35
89_I	302_G	0.647	0.35
336_V	339_C	0.647	0.35
348_A	399_K	0.646	0.35
495_M	498_F	0.645	0.35
99_T	105_A	0.645	0.35
299_F	365_K	0.644	0.35
263_N	266_V	0.643	0.35
111_M	223_R	0.640	0.35
460_T	463_V	0.640	0.35
364_T	398_E	0.640	0.35
340_M	420_S	0.639	0.35
455_I	494_M	0.638	0.35
18_L	128_R	0.636	0.35
429_I	446_F	0.636	0.35
14_G	22_D	0.636	0.35
407_Y	429_I	0.635	0.34
190_L	209_L	0.635	0.34
45_L	297_L	0.634	0.34
225_I	249_G	0.633	0.34
76_I	137_Y	0.632	0.34
184_R	187_E	0.630	0.34
453_V	502_L	0.630	0.34
91_A	156_R	0.629	0.34
425_T	429_I	0.627	0.34
143_I	153_I	0.627	0.34
406_G	410_C	0.626	0.34
34_A	38_L	0.626	0.34
277_L	463_V	0.626	0.34
164_V	248_A	0.626	0.34
100_A	152_E	0.624	0.34
143_I	501_H	0.623	0.34
73_V	381_N	0.623	0.34
159_A	362_F	0.622	0.33
82_T	387_G	0.622	0.33
377_D	388_V	0.622	0.33
451_H	501_H	0.622	0.33
374_P	392_R	0.621	0.33
28_Q	45_L	0.621	0.33
46_V	136_L	0.620	0.33
141_L	197_T	0.620	0.33
305_V	318_E	0.619	0.33
322_I	437_V	0.619	0.33
24_I	64_K	0.619	0.33
183_S	343_P	0.618	0.33
122_K	269_P	0.616	0.33
71_V	128_R	0.616	0.33
143_I	186_F	0.616	0.33
52_V	56_L	0.615	0.33
338_Q	485_R	0.615	0.33
14_G	45_L	0.615	0.33
146_L	183_S	0.613	0.33
72_G	75_N	0.613	0.33
87_I	394_I	0.613	0.33
144_V	186_F	0.612	0.33
94_G	435_R	0.609	0.32
98_S	152_E	0.609	0.32
494_M	515_D	0.608	0.32
448_P	463_V	0.608	0.32
210_L	247_V	0.607	0.32
236_A	506_I	0.607	0.32
54_E	209_L	0.605	0.32
237_A	432_F	0.604	0.32
458_Q	517_V	0.604	0.32
65_I	87_I	0.603	0.32
69_A	72_G	0.602	0.32
299_F	303_L	0.601	0.32
36_D	59_K	0.601	0.32
214_T	218_T	0.601	0.32
442_F	497_S	0.600	0.32
175_R	179_I	0.599	0.32
211_N	421_T	0.598	0.32
65_I	296_V	0.598	0.32
360_T	398_E	0.596	0.31
94_G	231_G	0.596	0.31
102_H	325_Y	0.596	0.31
238_L	252_L	0.596	0.31
236_A	262_D	0.596	0.31
424_V	430_P	0.595	0.31
102_H	115_P	0.595	0.31
344_V	371_F	0.594	0.31
233_I	250_A	0.594	0.31
170_F	289_A	0.593	0.31
91_A	295_E	0.593	0.31
102_H	277_L	0.591	0.31
466_R	473_D	0.590	0.31
76_I	314_M	0.589	0.31
466_R	470_I	0.588	0.31
341_K	419_R	0.588	0.31
65_I	300_A	0.588	0.31
165_H	193_A	0.588	0.31
76_I	120_S	0.588	0.31
6_V	97_I	0.587	0.31
184_R	188_E	0.587	0.31
241_A	250_A	0.587	0.31
43_A	481_M	0.586	0.31
204_K	382_E	0.584	0.31
350_Q	412_S	0.583	0.31
335_L	339_C	0.582	0.30
437_V	440_N	0.581	0.30
179_I	232_I	0.580	0.30
47_R	276_H	0.580	0.30
466_R	469_R	0.579	0.30
12_N	517_V	0.577	0.30
332_I	354_T	0.577	0.30
98_S	103_T	0.576	0.30
47_R	229_R	0.575	0.30
81_A	106_M	0.575	0.30
201_P	231_G	0.574	0.30
232_I	317_D	0.573	0.30
480_T	497_S	0.573	0.30
230_G	258_E	0.571	0.30
222_V	245_G	0.570	0.30
304_P	316_K	0.569	0.29
110_L	225_I	0.569	0.29
470_I	479_A	0.569	0.29
170_F	336_V	0.569	0.29
465_G	469_R	0.568	0.29
165_H	181_V	0.567	0.29
4_V	20_E	0.567	0.29
108_S	159_A	0.566	0.29
287_N	295_E	0.564	0.29
39_H	513_V	0.563	0.29
428_Y	437_V	0.562	0.29
29_K	32_A	0.562	0.29
193_A	512_N	0.560	0.29
156_R	445_D	0.560	0.29
122_K	239_L	0.560	0.29
58_N	269_P	0.560	0.29
195_I	248_A	0.560	0.29
426_A	431_H	0.559	0.29
257_V	262_D	0.558	0.29
67_G	496_L	0.558	0.29
33_D	51_K	0.557	0.29
99_T	288_V	0.557	0.29
115_P	251_A	0.556	0.29
372_L	394_I	0.556	0.29
10_M	96_T	0.556	0.29
387_G	409_N	0.556	0.29
71_V	152_E	0.555	0.28
98_S	299_F	0.555	0.28
420_S	426_A	0.554	0.28
479_A	497_S	0.554	0.28
375_R	392_R	0.554	0.28
344_V	394_I	0.553	0.28
334_S	373_K	0.553	0.28
113_H	116_Q	0.552	0.28
311_L	365_K	0.552	0.28
316_K	383_V	0.552	0.28
338_Q	484_G	0.550	0.28
68_R	72_G	0.550	0.28
136_L	209_L	0.549	0.28
141_L	165_H	0.549	0.28
347_V	415_V	0.548	0.28
59_K	62_S	0.547	0.28
47_R	279_A	0.547	0.28
6_V	41_F	0.547	0.28
89_I	481_M	0.546	0.28
340_M	417_G	0.546	0.28
198_V	222_V	0.546	0.28
121_V	311_L	0.546	0.28
172_T	211_N	0.545	0.28
232_I	346_D	0.545	0.28
489_G	493_I	0.545	0.28
134_S	248_A	0.544	0.28
370_G	388_V	0.544	0.28
348_A	416_T	0.544	0.28
485_R	490_G	0.543	0.28
19_I	519_V	0.543	0.28
234_D	309_I	0.542	0.28
217_K	475_D	0.542	0.28
325_Y	384_N	0.542	0.28
360_T	400_I	0.542	0.28
411_I	516_I	0.541	0.28
171_L	498_F	0.541	0.28
33_D	37_E	0.540	0.27
18_L	148_R	0.540	0.27
30_N	211_N	0.540	0.27
457_H	482_Q	0.540	0.27
413_V	437_V	0.539	0.27
173_E	216_A	0.539	0.27
250_A	268_H	0.538	0.27
183_S	454_Y	0.538	0.27
462_G	477_N	0.538	0.27
147_G	276_H	0.538	0.27
456_Q	502_L	0.538	0.27
146_L	304_P	0.537	0.27
7_S	50_T	0.537	0.27
146_L	442_F	0.536	0.27
157_A	272_I	0.535	0.27
98_S	289_A	0.534	0.27
10_M	314_M	0.534	0.27
163_T	509_E	0.533	0.27
200_T	209_L	0.533	0.27
68_R	229_R	0.533	0.27
164_V	501_H	0.533	0.27
146_L	151_S	0.531	0.27
120_S	519_V	0.531	0.27
17_P	294_E	0.531	0.27
325_Y	379_T	0.530	0.27
40_T	503_E	0.530	0.27
91_A	445_D	0.530	0.27
332_I	424_V	0.530	0.27
7_S	11_S	0.528	0.27
104_F	141_L	0.528	0.27
502_L	505_K	0.528	0.27
65_I	464_I	0.528	0.27
54_E	77_D	0.527	0.27
91_A	288_V	0.527	0.27
183_S	440_N	0.527	0.27
104_F	108_S	0.527	0.27
223_R	277_L	0.526	0.26
163_T	192_S	0.526	0.26
47_R	69_A	0.526	0.26
91_A	148_R	0.525	0.26
385_A	522_I	0.525	0.26
453_V	471_L	0.525	0.26
255_F	280_S	0.525	0.26
14_G	297_L	0.524	0.26
419_R	509_E	0.524	0.26
240_E	469_R	0.523	0.26
4_V	505_K	0.523	0.26
35_E	39_H	0.523	0.26
371_F	495_M	0.520	0.26
132_V	292_V	0.520	0.26
14_G	290_A	0.520	0.26
235_E	279_A	0.519	0.26
355_I	358_L	0.519	0.26
131_Y	270_L	0.518	0.26
361_S	398_E	0.517	0.26
243_E	264_K	0.517	0.26
62_S	217_K	0.517	0.26
102_H	494_M	0.517	0.26
143_I	456_Q	0.516	0.26
99_T	302_G	0.516	0.26
62_S	514_P	0.516	0.26
114_I	436_I	0.514	0.26
142_G	467_V	0.514	0.26
250_A	383_V	0.514	0.26
15_L	19_I	0.514	0.26
217_K	222_V	0.514	0.26
307_S	457_H	0.514	0.26
29_K	37_E	0.514	0.26
96_T	99_T	0.514	0.26
11_S	144_V	0.513	0.26
141_L	309_I	0.513	0.26
462_G	471_L	0.513	0.26
11_S	15_L	0.513	0.26
10_M	177_K	0.512	0.26
384_N	389_A	0.511	0.25
403_S	430_P	0.511	0.25
14_G	102_H	0.510	0.25
76_I	383_V	0.508	0.25
334_S	363_I	0.508	0.25
89_I	303_L	0.508	0.25
340_M	422_F	0.508	0.25
196_I	223_R	0.507	0.25
326_H	366_A	0.507	0.25
282_K	378_S	0.505	0.25
344_V	415_V	0.505	0.25
426_A	429_I	0.505	0.25
507_V	511_T	0.505	0.25
223_R	251_A	0.503	0.25
175_R	273_A	0.503	0.25
7_S	120_S	0.502	0.25
243_E	269_P	0.502	0.25
346_D	404_E	0.502	0.25
39_H	62_S	0.501	0.25
148_R	160_F	0.501	0.25
123_S	127_N	0.501	0.25
435_R	445_D	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ygyA	4	0.9962	100	0.353	Contact Map
3k5pA	3	0.7333	100	0.565	Contact Map
1sc6A	4	0.7181	100	0.57	Contact Map
2g76A	2	0.5714	100	0.617	Contact Map
2d0iA	2	0.6171	100	0.63	Contact Map
4g2nA	3	0.5886	100	0.638	Contact Map
1wwkA	2	0.5695	100	0.64	Contact Map
2w2kA	2	0.6057	100	0.642	Contact Map
2gcgA	2	0.5924	100	0.643	Contact Map
3ba1A	2	0.581	100	0.644	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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