GREMLIN Database
SERA - D-3-phosphoglycerate dehydrogenase
UniProt: P35136 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 525 (520)
Sequences: 1486 (815)
Seq/√Len: 35.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
234_D237_A5.7721.00
222_V247_V4.9671.00
220_K246_H4.8971.00
57_F66_V4.6631.00
212_K240_E4.6051.00
111_M195_I4.0861.00
110_L249_G3.9831.00
46_V76_I3.9821.00
187_E217_K3.8901.00
211_N214_T3.8601.00
44_L52_V3.8571.00
182_N192_S3.6341.00
208_G234_D3.3921.00
25_E41_F3.3751.00
239_L268_H3.3111.00
185_T188_E3.2451.00
243_E268_H3.1931.00
198_V232_I3.1291.00
473_D509_E3.1091.00
242_L270_L2.9601.00
330_G369_S2.9061.00
239_L243_E2.8891.00
141_L157_A2.8121.00
196_I222_V2.8011.00
31_V55_D2.7941.00
221_G247_V2.6711.00
498_F502_L2.6131.00
57_F86_V2.6051.00
30_N33_D2.5671.00
367_L413_V2.5001.00
202_L207_K2.4981.00
215_I246_H2.4381.00
208_G256_E2.4021.00
223_R248_A2.3931.00
66_V86_V2.3881.00
127_N130_A2.3701.00
347_V371_F2.3661.00
465_G468_G2.3651.00
184_R189_V2.3581.00
215_I218_T2.3330.99
195_I223_R2.3190.99
12_N16_Q2.3090.99
118_N122_K2.2610.99
190_L218_T2.2280.99
346_D416_T2.2090.99
218_T222_V2.1970.99
479_A485_R2.1660.99
35_E55_D2.1590.99
16_Q20_E2.1290.99
191_E217_K2.1250.99
104_F160_F2.1080.99
104_F157_A2.0950.99
35_E59_K2.0770.99
54_E58_N2.0770.99
438_E441_G2.0690.99
424_V427_T2.0610.99
141_L162_M2.0360.99
35_E56_L2.0260.98
110_L223_R2.0220.98
54_E83_K2.0080.98
121_V273_A1.9840.98
465_G472_G1.9780.98
210_L215_I1.9430.98
483_V494_M1.9250.98
216_A244_N1.9190.98
410_C437_V1.9140.98
368_L396_F1.8720.97
11_S286_L1.8650.97
31_V35_E1.8560.97
38_L61_T1.8530.97
268_H271_V1.8430.97
42_D62_S1.8420.97
37_E41_F1.8300.97
103_T227_C1.8270.97
142_G189_V1.8260.97
218_T246_H1.8250.97
336_V415_V1.8120.97
110_L251_A1.8090.97
508_K512_N1.8050.97
208_G211_N1.7980.97
243_E270_L1.7980.97
163_T182_N1.7910.97
137_Y161_G1.7880.97
190_L214_T1.7720.96
31_V53_T1.7570.96
122_K267_D1.7510.96
422_F440_N1.7300.96
108_S160_F1.7300.96
242_L268_H1.6860.95
38_L41_F1.6790.95
508_K511_T1.6620.95
212_K237_A1.6540.95
43_A296_V1.6540.95
243_E267_D1.6530.95
102_H106_M1.6250.94
120_S131_Y1.6110.94
165_H184_R1.6070.94
211_N237_A1.6050.94
255_F273_A1.5880.93
211_N234_D1.5870.93
110_L272_I1.5860.93
105_A114_I1.5710.93
176_A183_S1.5690.93
239_L252_L1.5630.93
190_L210_L1.5570.93
119_I123_S1.5450.93
67_G292_V1.5420.92
474_N509_E1.5180.92
140_T163_T1.5140.92
221_G244_N1.5120.92
134_S223_R1.5070.92
241_A247_V1.5060.92
33_D36_D1.5060.92
134_S195_I1.5050.91
236_A264_K1.5010.91
40_T62_S1.4920.91
61_T84_H1.4730.91
142_G193_A1.4720.91
454_Y495_M1.4640.90
52_V66_V1.4620.90
21_S301_K1.4620.90
165_H192_S1.4330.89
115_P272_I1.4330.89
83_K391_E1.4270.89
504_D508_K1.4220.89
440_N456_Q1.4190.89
120_S125_E1.4170.89
329_A411_I1.4160.89
106_M114_I1.4130.89
144_V198_V1.3980.88
210_L218_T1.3960.88
213_E217_K1.3900.88
9_K129_T1.3720.87
223_R249_G1.3580.87
236_A240_E1.3580.87
351_Y364_T1.3510.86
102_H114_I1.3510.86
215_I241_A1.3500.86
233_I252_L1.3320.86
216_A246_H1.3310.85
481_M494_M1.3270.85
221_G245_G1.3190.85
485_R492_A1.3150.85
299_F305_V1.3130.85
173_E177_K1.3120.85
73_V76_I1.3060.84
427_T430_P1.3040.84
143_I154_A1.3000.84
298_Q303_L1.2970.84
424_V428_Y1.2920.84
459_D492_A1.2900.84
7_S44_L1.2830.83
94_G288_V1.2790.83
53_T56_L1.2700.83
240_E243_E1.2690.83
239_L264_K1.2630.82
102_H105_A1.2520.82
242_L271_V1.2470.81
341_K520_K1.2430.81
106_M227_C1.2430.81
27_V37_E1.2390.81
3_R25_E1.2380.81
12_N19_I1.2340.81
462_G468_G1.2330.81
6_V14_G1.2320.81
231_G235_E1.2190.80
348_A397_S1.2160.80
351_Y398_E1.2140.80
27_V41_F1.2050.79
58_N80_E1.2040.79
485_R489_G1.2040.79
351_Y360_T1.2000.79
9_K49_A1.1990.79
299_F302_G1.1900.78
425_T428_Y1.1760.77
102_H274_T1.1740.77
29_K33_D1.1740.77
329_A367_L1.1600.76
212_K216_A1.1590.76
368_L386_G1.1570.76
347_V368_L1.1560.76
121_V266_V1.1470.76
32_A55_D1.1400.75
252_L271_V1.1400.75
485_R499_D1.1370.75
186_F190_L1.1370.75
204_K207_K1.1350.75
184_R192_S1.1350.75
345_Q418_D1.1300.75
221_G246_H1.1280.74
239_L267_D1.1260.74
212_K244_N1.1200.74
209_L252_L1.1170.74
94_G289_A1.1140.73
348_A414_K1.1060.73
486_K491_E1.0990.72
297_L301_K1.0970.72
470_I510_L1.0960.72
60_M84_H1.0870.72
410_C425_T1.0860.72
342_E419_R1.0840.71
236_A263_N1.0790.71
210_L224_L1.0700.70
44_L56_L1.0690.70
54_E80_E1.0670.70
144_V210_L1.0630.70
332_I436_I1.0600.70
224_L233_I1.0550.69
503_E506_I1.0550.69
89_I494_M1.0490.69
453_V498_F1.0490.69
451_H521_L1.0470.69
507_V519_V1.0440.68
140_T165_H1.0430.68
188_E192_S1.0420.68
469_R473_D1.0420.68
58_N84_H1.0420.68
236_A256_E1.0370.68
436_I448_P1.0370.68
39_H59_K1.0300.67
13_D286_L1.0290.67
457_H494_M1.0250.67
37_E40_T1.0240.67
25_E28_Q1.0220.67
459_D462_G1.0210.67
39_H61_T1.0210.67
46_V52_V1.0190.67
166_V181_V1.0190.67
152_E155_Q1.0170.66
214_T217_K1.0150.66
479_A499_D1.0120.66
466_R515_D1.0120.66
257_V261_V1.0080.66
157_A162_M1.0080.66
476_I506_I1.0050.65
239_L242_L1.0050.65
251_A272_I1.0000.65
222_V246_H1.0000.65
350_Q414_K0.9990.65
209_L232_I0.9980.65
342_E418_D0.9940.65
218_T247_V0.9910.64
89_I100_A0.9910.64
510_L519_V0.9860.64
6_V24_I0.9820.64
57_F84_H0.9790.63
143_I197_T0.9780.63
479_A489_G0.9750.63
176_A181_V0.9740.63
215_I224_L0.9720.63
158_R164_V0.9690.63
295_E457_H0.9650.62
151_S175_R0.9630.62
7_S52_V0.9620.62
426_A430_P0.9600.62
296_V300_A0.9580.62
210_L214_T0.9580.62
218_T244_N0.9570.62
456_Q491_E0.9560.62
121_V255_F0.9540.61
332_I335_L0.9500.61
425_T438_E0.9470.61
98_S128_R0.9460.61
8_D289_A0.9450.61
346_D395_S0.9440.61
189_V193_A0.9440.61
170_F209_L0.9420.60
105_A108_S0.9390.60
153_I197_T0.9370.60
457_H483_V0.9370.60
389_A396_F0.9350.60
27_V33_D0.9350.60
146_L181_V0.9350.60
116_Q272_I0.9330.60
329_A363_I0.9320.60
213_E237_A0.9280.59
240_E244_N0.9260.59
76_I148_R0.9230.59
120_S127_N0.9210.59
187_E213_E0.9210.59
98_S160_F0.9200.59
95_N99_T0.9190.58
420_S427_T0.9140.58
414_K421_T0.9140.58
509_E512_N0.9130.58
260_P266_V0.9130.58
474_N506_I0.9100.58
3_R40_T0.9100.58
7_S46_V0.9080.58
117_A131_Y0.9070.57
349_I367_L0.9010.57
504_D521_L0.9010.57
152_E156_R0.8990.57
232_I481_M0.8950.56
369_S382_E0.8930.56
187_E191_E0.8930.56
463_V480_T0.8870.56
440_N467_V0.8870.56
156_R160_F0.8850.56
111_M134_S0.8850.56
305_V311_L0.8840.56
186_F210_L0.8840.56
224_L247_V0.8820.55
502_L506_I0.8780.55
193_A196_I0.8770.55
8_D105_A0.8750.55
190_L222_V0.8730.55
25_E37_E0.8720.54
416_T421_T0.8720.54
241_A246_H0.8710.54
186_F189_V0.8710.54
110_L248_A0.8710.54
18_L296_V0.8710.54
89_I292_V0.8690.54
144_V189_V0.8680.54
46_V79_D0.8650.54
158_R180_G0.8650.54
165_H189_V0.8580.53
23_F301_K0.8560.53
25_E29_K0.8530.53
49_A149_I0.8530.53
14_G18_L0.8530.53
57_F80_E0.8520.53
105_A277_L0.8510.53
82_T280_S0.8490.52
376_V392_R0.8470.52
6_V15_L0.8470.52
41_F61_T0.8470.52
124_R267_D0.8450.52
479_A492_A0.8430.52
106_M115_P0.8380.52
244_N504_D0.8350.51
13_D16_Q0.8340.51
466_R513_V0.8330.51
102_H251_A0.8330.51
328_I332_I0.8310.51
135_E287_N0.8270.51
97_I137_Y0.8240.50
136_L160_F0.8240.50
369_S373_K0.8230.50
462_G492_A0.8220.50
45_L296_V0.8210.50
213_E236_A0.8150.50
26_I325_Y0.8140.49
213_E216_A0.8140.49
279_A285_Q0.8120.49
412_S425_T0.8120.49
182_N188_E0.8120.49
331_K450_G0.8110.49
334_S338_Q0.8060.49
71_V93_N0.8060.49
10_M159_A0.8030.49
327_Q330_G0.8030.49
38_L60_M0.8020.48
71_V91_A0.8020.48
332_I413_V0.8010.48
146_L171_L0.7980.48
164_V181_V0.7960.48
18_L45_L0.7960.48
21_S297_L0.7950.48
25_E38_L0.7950.48
116_Q131_Y0.7940.48
266_V273_A0.7930.48
151_S181_V0.7920.48
32_A39_H0.7910.47
146_L166_V0.7910.47
86_V395_S0.7880.47
468_G472_G0.7880.47
467_V494_M0.7850.47
152_E202_L0.7850.47
261_V266_V0.7840.47
380_V388_V0.7830.47
47_R68_R0.7810.47
187_E214_T0.7770.46
136_L195_I0.7770.46
118_N272_I0.7750.46
38_L52_V0.7720.46
100_A434_E0.7710.46
106_M251_A0.7700.46
239_L270_L0.7690.46
116_Q251_A0.7650.45
288_V457_H0.7650.45
3_R33_D0.7620.45
459_D485_R0.7620.45
66_V76_I0.7600.45
231_G279_A0.7590.45
424_V436_I0.7550.44
230_G259_P0.7540.44
257_V260_P0.7510.44
122_K273_A0.7500.44
89_I307_S0.7460.44
505_K509_E0.7450.44
155_Q161_G0.7450.44
89_I295_E0.7440.43
456_Q518_S0.7440.43
238_L247_V0.7430.43
24_I27_V0.7420.43
46_V82_T0.7410.43
67_G440_N0.7410.43
46_V280_S0.7410.43
220_K244_N0.7400.43
120_S130_A0.7390.43
116_Q120_S0.7380.43
500_R510_L0.7370.43
89_I296_V0.7370.43
130_A269_P0.7360.43
47_R72_G0.7360.43
464_I481_M0.7350.43
99_T104_F0.7350.43
396_F469_R0.7350.43
477_N499_D0.7320.42
5_L41_F0.7310.42
65_I299_F0.7310.42
445_D494_M0.7290.42
65_I89_I0.7290.42
454_Y522_I0.7270.42
104_F159_A0.7250.42
65_I302_G0.7240.42
222_V242_L0.7240.42
181_V233_I0.7240.42
98_S155_Q0.7240.42
52_V109_S0.7220.42
128_R302_G0.7210.41
99_T255_F0.7210.41
54_E344_V0.7180.41
109_S115_P0.7180.41
233_I247_V0.7130.41
277_L280_S0.7120.41
272_I431_H0.7100.41
109_S264_K0.7100.41
118_N273_A0.7090.40
196_I324_P0.7070.40
57_F61_T0.7070.40
116_Q269_P0.7050.40
195_I225_I0.7030.40
10_M286_L0.7010.40
106_M200_T0.7000.40
10_M45_L0.6990.40
95_N229_R0.6990.40
270_L473_D0.6990.40
196_I217_K0.6980.40
144_V209_L0.6970.39
483_V492_A0.6970.39
72_G254_V0.6960.39
106_M272_I0.6950.39
368_L389_A0.6930.39
336_V340_M0.6920.39
14_G17_P0.6900.39
325_Y409_N0.6890.39
444_I473_D0.6890.39
298_Q306_M0.6890.39
347_V413_V0.6890.39
24_I28_Q0.6880.39
459_D479_A0.6870.39
122_K510_L0.6860.39
102_H107_I0.6860.39
491_E517_V0.6840.38
337_S371_F0.6840.38
428_Y431_H0.6840.38
457_H481_M0.6840.38
464_I483_V0.6840.38
161_G295_E0.6830.38
5_L81_A0.6830.38
420_S429_I0.6830.38
459_D477_N0.6830.38
40_T61_T0.6820.38
184_R193_A0.6780.38
89_I305_V0.6770.38
94_G287_N0.6770.38
55_D58_N0.6760.38
91_A291_Q0.6740.38
327_Q331_K0.6740.38
354_T409_N0.6740.38
66_V380_V0.6730.38
215_I220_K0.6730.38
174_E251_A0.6720.37
128_R446_F0.6680.37
16_Q19_I0.6680.37
82_T483_V0.6670.37
367_L371_F0.6660.37
274_T288_V0.6660.37
35_E57_F0.6660.37
366_A507_V0.6650.37
212_K246_H0.6650.37
11_S176_A0.6640.37
120_S123_S0.6630.37
143_I200_T0.6630.37
79_D83_K0.6610.37
173_E183_S0.6600.36
295_E307_S0.6590.36
215_I247_V0.6590.36
442_F481_M0.6590.36
471_L506_I0.6580.36
38_L56_L0.6580.36
332_I446_F0.6570.36
114_I131_Y0.6570.36
98_S146_L0.6570.36
38_L44_L0.6550.36
196_I247_V0.6550.36
99_T128_R0.6550.36
345_Q416_T0.6540.36
7_S24_I0.6530.36
221_G242_L0.6530.36
64_K495_M0.6500.36
445_D448_P0.6500.36
17_P295_E0.6490.36
435_R479_A0.6480.35
4_V333_G0.6480.35
121_V261_V0.6480.35
73_V78_I0.6480.35
89_I302_G0.6470.35
336_V339_C0.6470.35
348_A399_K0.6460.35
495_M498_F0.6450.35
99_T105_A0.6450.35
299_F365_K0.6440.35
263_N266_V0.6430.35
111_M223_R0.6400.35
460_T463_V0.6400.35
364_T398_E0.6400.35
340_M420_S0.6390.35
455_I494_M0.6380.35
18_L128_R0.6360.35
429_I446_F0.6360.35
14_G22_D0.6360.35
407_Y429_I0.6350.34
190_L209_L0.6350.34
45_L297_L0.6340.34
225_I249_G0.6330.34
76_I137_Y0.6320.34
184_R187_E0.6300.34
453_V502_L0.6300.34
91_A156_R0.6290.34
425_T429_I0.6270.34
143_I153_I0.6270.34
406_G410_C0.6260.34
34_A38_L0.6260.34
277_L463_V0.6260.34
164_V248_A0.6260.34
100_A152_E0.6240.34
143_I501_H0.6230.34
73_V381_N0.6230.34
159_A362_F0.6220.33
82_T387_G0.6220.33
377_D388_V0.6220.33
451_H501_H0.6220.33
374_P392_R0.6210.33
28_Q45_L0.6210.33
46_V136_L0.6200.33
141_L197_T0.6200.33
305_V318_E0.6190.33
322_I437_V0.6190.33
24_I64_K0.6190.33
183_S343_P0.6180.33
122_K269_P0.6160.33
71_V128_R0.6160.33
143_I186_F0.6160.33
52_V56_L0.6150.33
338_Q485_R0.6150.33
14_G45_L0.6150.33
146_L183_S0.6130.33
72_G75_N0.6130.33
87_I394_I0.6130.33
144_V186_F0.6120.33
94_G435_R0.6090.32
98_S152_E0.6090.32
494_M515_D0.6080.32
448_P463_V0.6080.32
210_L247_V0.6070.32
236_A506_I0.6070.32
54_E209_L0.6050.32
237_A432_F0.6040.32
458_Q517_V0.6040.32
65_I87_I0.6030.32
69_A72_G0.6020.32
299_F303_L0.6010.32
36_D59_K0.6010.32
214_T218_T0.6010.32
442_F497_S0.6000.32
175_R179_I0.5990.32
211_N421_T0.5980.32
65_I296_V0.5980.32
360_T398_E0.5960.31
94_G231_G0.5960.31
102_H325_Y0.5960.31
238_L252_L0.5960.31
236_A262_D0.5960.31
424_V430_P0.5950.31
102_H115_P0.5950.31
344_V371_F0.5940.31
233_I250_A0.5940.31
170_F289_A0.5930.31
91_A295_E0.5930.31
102_H277_L0.5910.31
466_R473_D0.5900.31
76_I314_M0.5890.31
466_R470_I0.5880.31
341_K419_R0.5880.31
65_I300_A0.5880.31
165_H193_A0.5880.31
76_I120_S0.5880.31
6_V97_I0.5870.31
184_R188_E0.5870.31
241_A250_A0.5870.31
43_A481_M0.5860.31
204_K382_E0.5840.31
350_Q412_S0.5830.31
335_L339_C0.5820.30
437_V440_N0.5810.30
179_I232_I0.5800.30
47_R276_H0.5800.30
466_R469_R0.5790.30
12_N517_V0.5770.30
332_I354_T0.5770.30
98_S103_T0.5760.30
47_R229_R0.5750.30
81_A106_M0.5750.30
201_P231_G0.5740.30
232_I317_D0.5730.30
480_T497_S0.5730.30
230_G258_E0.5710.30
222_V245_G0.5700.30
304_P316_K0.5690.29
110_L225_I0.5690.29
470_I479_A0.5690.29
170_F336_V0.5690.29
465_G469_R0.5680.29
165_H181_V0.5670.29
4_V20_E0.5670.29
108_S159_A0.5660.29
287_N295_E0.5640.29
39_H513_V0.5630.29
428_Y437_V0.5620.29
29_K32_A0.5620.29
193_A512_N0.5600.29
156_R445_D0.5600.29
122_K239_L0.5600.29
58_N269_P0.5600.29
195_I248_A0.5600.29
426_A431_H0.5590.29
257_V262_D0.5580.29
67_G496_L0.5580.29
33_D51_K0.5570.29
99_T288_V0.5570.29
115_P251_A0.5560.29
372_L394_I0.5560.29
10_M96_T0.5560.29
387_G409_N0.5560.29
71_V152_E0.5550.28
98_S299_F0.5550.28
420_S426_A0.5540.28
479_A497_S0.5540.28
375_R392_R0.5540.28
344_V394_I0.5530.28
334_S373_K0.5530.28
113_H116_Q0.5520.28
311_L365_K0.5520.28
316_K383_V0.5520.28
338_Q484_G0.5500.28
68_R72_G0.5500.28
136_L209_L0.5490.28
141_L165_H0.5490.28
347_V415_V0.5480.28
59_K62_S0.5470.28
47_R279_A0.5470.28
6_V41_F0.5470.28
89_I481_M0.5460.28
340_M417_G0.5460.28
198_V222_V0.5460.28
121_V311_L0.5460.28
172_T211_N0.5450.28
232_I346_D0.5450.28
489_G493_I0.5450.28
134_S248_A0.5440.28
370_G388_V0.5440.28
348_A416_T0.5440.28
485_R490_G0.5430.28
19_I519_V0.5430.28
234_D309_I0.5420.28
217_K475_D0.5420.28
325_Y384_N0.5420.28
360_T400_I0.5420.28
411_I516_I0.5410.28
171_L498_F0.5410.28
33_D37_E0.5400.27
18_L148_R0.5400.27
30_N211_N0.5400.27
457_H482_Q0.5400.27
413_V437_V0.5390.27
173_E216_A0.5390.27
250_A268_H0.5380.27
183_S454_Y0.5380.27
462_G477_N0.5380.27
147_G276_H0.5380.27
456_Q502_L0.5380.27
146_L304_P0.5370.27
7_S50_T0.5370.27
146_L442_F0.5360.27
157_A272_I0.5350.27
98_S289_A0.5340.27
10_M314_M0.5340.27
163_T509_E0.5330.27
200_T209_L0.5330.27
68_R229_R0.5330.27
164_V501_H0.5330.27
146_L151_S0.5310.27
120_S519_V0.5310.27
17_P294_E0.5310.27
325_Y379_T0.5300.27
40_T503_E0.5300.27
91_A445_D0.5300.27
332_I424_V0.5300.27
7_S11_S0.5280.27
104_F141_L0.5280.27
502_L505_K0.5280.27
65_I464_I0.5280.27
54_E77_D0.5270.27
91_A288_V0.5270.27
183_S440_N0.5270.27
104_F108_S0.5270.27
223_R277_L0.5260.26
163_T192_S0.5260.26
47_R69_A0.5260.26
91_A148_R0.5250.26
385_A522_I0.5250.26
453_V471_L0.5250.26
255_F280_S0.5250.26
14_G297_L0.5240.26
419_R509_E0.5240.26
240_E469_R0.5230.26
4_V505_K0.5230.26
35_E39_H0.5230.26
371_F495_M0.5200.26
132_V292_V0.5200.26
14_G290_A0.5200.26
235_E279_A0.5190.26
355_I358_L0.5190.26
131_Y270_L0.5180.26
361_S398_E0.5170.26
243_E264_K0.5170.26
62_S217_K0.5170.26
102_H494_M0.5170.26
143_I456_Q0.5160.26
99_T302_G0.5160.26
62_S514_P0.5160.26
114_I436_I0.5140.26
142_G467_V0.5140.26
250_A383_V0.5140.26
15_L19_I0.5140.26
217_K222_V0.5140.26
307_S457_H0.5140.26
29_K37_E0.5140.26
96_T99_T0.5140.26
11_S144_V0.5130.26
141_L309_I0.5130.26
462_G471_L0.5130.26
11_S15_L0.5130.26
10_M177_K0.5120.26
384_N389_A0.5110.25
403_S430_P0.5110.25
14_G102_H0.5100.25
76_I383_V0.5080.25
334_S363_I0.5080.25
89_I303_L0.5080.25
340_M422_F0.5080.25
196_I223_R0.5070.25
326_H366_A0.5070.25
282_K378_S0.5050.25
344_V415_V0.5050.25
426_A429_I0.5050.25
507_V511_T0.5050.25
223_R251_A0.5030.25
175_R273_A0.5030.25
7_S120_S0.5020.25
243_E269_P0.5020.25
346_D404_E0.5020.25
39_H62_S0.5010.25
148_R160_F0.5010.25
123_S127_N0.5010.25
435_R445_D0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ygyA 4 0.9962 100 0.353 Contact Map
3k5pA 3 0.7333 100 0.565 Contact Map
1sc6A 4 0.7181 100 0.57 Contact Map
2g76A 2 0.5714 100 0.617 Contact Map
2d0iA 2 0.6171 100 0.63 Contact Map
4g2nA 3 0.5886 100 0.638 Contact Map
1wwkA 2 0.5695 100 0.64 Contact Map
2w2kA 2 0.6057 100 0.642 Contact Map
2gcgA 2 0.5924 100 0.643 Contact Map
3ba1A 2 0.581 100 0.644 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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