COMQ - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

COMQ - Competence regulatory protein ComQ

UniProt:	P33690	Sequences: MKEIVEQNIFNEDLSQLLYSFIDSKETFSFAESTILHYVVFGGENLDVATRLGAGIEILILSSDIMDDLEDEDNHHALWMKINRSESLNAALSLYTVGLTSIYSLNNNPLIFKYVLKYVNEAMQGQHDDITNKSKTEDESLEVIRLKCGSLIALANVAGVLLATGEYNETVERYSYYKGIIAQISGDYYVLLSGNRSDIEKNKHTLIYLYLKRLFNDASEDLLYLISHKDLYYKSLLDKEKFQEKLIKAGVTQYISVLLEIYKQKCISAIEQLNLDKEKKELIKECLLSYTKGDTRCKT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	299 (275)
Sequences:	7367 (4975)
Seq/√Len:	300.0

ECOLI - ISPB ISPA
BACSU - COMQ HEPS2 ISPA
HALSA - Q9HQI3 Q9HND0
SULSO - GGPS HEXPP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
177_Y	265_K	3.166	1.00
221_D	241_K	3.144	1.00
177_Y	262_Y	3.072	1.00
267_I	288_L	3.011	1.00
214_L	254_Y	2.999	1.00
244_E	248_K	2.833	1.00
157_V	172_E	2.755	1.00
267_I	284_K	2.752	1.00
258_L	261_I	2.722	1.00
210_Y	254_Y	2.653	1.00
145_R	176_Y	2.571	1.00
235_S	238_D	2.567	1.00
153_A	172_E	2.540	1.00
210_Y	251_V	2.485	1.00
250_G	253_Q	2.386	1.00
264_Q	268_S	2.317	1.00
173_R	269_A	2.261	1.00
38_Y	48_V	2.253	1.00
37_H	171_V	2.175	1.00
70_E	126_Q	2.133	1.00
271_E	284_K	2.130	1.00
188_Y	255_I	2.103	1.00
169_E	173_R	2.021	1.00
280_K	284_K	1.926	1.00
253_Q	257_V	1.887	1.00
153_A	176_Y	1.876	1.00
261_I	265_K	1.861	1.00
114_Y	157_V	1.859	1.00
160_V	171_V	1.831	1.00
126_Q	129_D	1.829	1.00
65_I	82_I	1.812	1.00
114_Y	161_L	1.808	1.00
268_S	271_E	1.773	1.00
247_I	252_T	1.767	1.00
136_T	139_E	1.751	1.00
66_M	92_L	1.718	1.00
184_I	255_I	1.718	1.00
156_N	175_S	1.717	1.00
260_E	264_Q	1.711	1.00
51_R	104_S	1.702	1.00
111_I	158_A	1.695	1.00
257_V	261_I	1.678	1.00
37_H	156_N	1.664	1.00
69_L	84_R	1.659	1.00
211_L	246_L	1.651	1.00
253_Q	256_S	1.647	1.00
241_K	244_E	1.643	1.00
66_M	91_A	1.590	1.00
210_Y	213_R	1.579	1.00
173_R	177_Y	1.577	1.00
219_S	223_L	1.558	1.00
63_S	122_A	1.557	1.00
188_Y	252_T	1.556	1.00
246_L	251_V	1.553	1.00
257_V	260_E	1.552	1.00
140_S	144_I	1.551	1.00
137_E	213_R	1.540	1.00
188_Y	256_S	1.533	1.00
100_T	117_K	1.509	1.00
221_D	224_Y	1.506	1.00
258_L	262_Y	1.496	1.00
170_T	272_Q	1.487	1.00
137_E	258_L	1.475	1.00
267_I	287_L	1.462	1.00
160_V	165_G	1.440	1.00
145_R	180_I	1.439	1.00
135_K	139_E	1.434	1.00
104_S	113_K	1.425	1.00
222_L	242_F	1.415	1.00
180_I	262_Y	1.415	1.00
97_V	100_T	1.406	1.00
241_K	245_K	1.403	1.00
153_A	157_V	1.398	1.00
274_N	280_K	1.393	1.00
55_G	102_I	1.385	1.00
142_E	146_L	1.380	1.00
110_L	167_Y	1.377	1.00
269_A	272_Q	1.367	1.00
73_D	197_S	1.364	1.00
159_G	163_A	1.364	1.00
210_Y	214_L	1.362	1.00
228_H	238_D	1.361	1.00
263_K	267_I	1.354	1.00
276_D	280_K	1.352	1.00
221_D	225_L	1.349	1.00
151_L	155_A	1.343	1.00
25_K	28_F	1.342	1.00
110_L	113_K	1.341	1.00
213_R	254_Y	1.340	1.00
220_E	224_Y	1.337	1.00
281_E	285_E	1.325	1.00
277_K	280_K	1.325	1.00
144_I	180_I	1.320	1.00
211_L	251_V	1.311	1.00
75_H	80_M	1.306	1.00
237_L	240_E	1.304	1.00
142_E	145_R	1.303	1.00
243_Q	247_I	1.297	1.00
263_K	291_T	1.297	1.00
177_Y	269_A	1.286	1.00
254_Y	257_V	1.273	1.00
223_L	227_S	1.256	1.00
121_E	146_L	1.254	1.00
185_S	259_L	1.243	1.00
174_Y	270_I	1.243	1.00
157_V	169_E	1.230	1.00
132_N	143_V	1.225	1.00
118_Y	154_L	1.224	1.00
70_E	89_N	1.216	1.00
100_T	120_N	1.213	1.00
185_S	256_S	1.206	1.00
19_Y	23_D	1.193	1.00
277_K	281_E	1.184	1.00
251_V	254_Y	1.179	1.00
271_E	280_K	1.173	1.00
137_E	210_Y	1.172	1.00
276_D	281_E	1.169	1.00
137_E	254_Y	1.166	1.00
170_T	269_A	1.162	1.00
192_L	252_T	1.156	1.00
262_Y	265_K	1.149	1.00
200_E	236_L	1.145	1.00
220_E	223_L	1.142	1.00
140_S	209_L	1.137	1.00
240_E	244_E	1.127	1.00
215_F	249_A	1.126	1.00
103_Y	112_F	1.125	1.00
288_L	292_K	1.119	1.00
174_Y	287_L	1.118	1.00
281_E	284_K	1.118	1.00
211_L	249_A	1.115	1.00
41_F	159_G	1.107	1.00
37_H	41_F	1.107	1.00
72_E	84_R	1.093	1.00
206_L	258_L	1.092	1.00
150_S	153_A	1.085	1.00
35_I	53_G	1.082	1.00
113_K	117_K	1.082	1.00
141_L	180_I	1.067	1.00
174_Y	269_A	1.067	1.00
264_Q	267_I	1.065	1.00
215_F	245_K	1.060	1.00
24_S	79_W	1.060	1.00
206_L	255_I	1.055	1.00
173_R	265_K	1.053	1.00
260_E	292_K	1.052	1.00
284_K	288_L	1.042	1.00
40_V	273_L	1.041	1.00
39_V	279_K	1.034	1.00
128_D	142_E	1.028	1.00
111_I	162_L	1.024	1.00
224_Y	228_H	1.017	1.00
38_Y	43_G	1.006	1.00
33_S	156_N	1.004	1.00
143_V	203_K	1.004	1.00
129_D	203_K	1.002	1.00
69_L	88_L	0.996	1.00
41_F	165_G	0.994	1.00
52_L	158_A	0.989	1.00
211_L	245_K	0.974	1.00
28_F	31_A	0.967	1.00
265_K	268_S	0.960	1.00
141_L	262_Y	0.955	1.00
41_F	163_A	0.947	1.00
244_E	247_I	0.946	1.00
40_V	171_V	0.945	1.00
189_Y	193_S	0.941	1.00
212_K	223_L	0.938	1.00
54_A	101_S	0.936	1.00
169_E	172_E	0.935	1.00
18_L	94_L	0.931	1.00
263_K	287_L	0.921	1.00
153_A	175_S	0.920	1.00
38_Y	163_A	0.919	1.00
176_Y	180_I	0.919	1.00
225_L	242_F	0.918	1.00
102_I	111_I	0.907	1.00
29_S	290_Y	0.907	1.00
110_L	161_L	0.906	1.00
210_Y	258_L	0.900	1.00
128_D	146_L	0.898	1.00
34_T	56_I	0.889	1.00
107_N	110_L	0.887	1.00
63_S	151_L	0.886	1.00
256_S	260_E	0.878	1.00
43_G	48_V	0.874	1.00
132_N	139_E	0.869	1.00
240_E	243_Q	0.865	1.00
188_Y	259_L	0.863	1.00
141_L	258_L	0.860	1.00
74_N	83_N	0.859	1.00
52_L	111_I	0.856	1.00
272_Q	280_K	0.856	1.00
44_E	47_D	0.855	1.00
33_S	178_K	0.855	1.00
238_D	241_K	0.844	1.00
52_L	162_L	0.843	1.00
137_E	209_L	0.835	1.00
182_A	186_G	0.830	1.00
170_T	174_Y	0.830	1.00
149_G	180_I	0.827	1.00
36_L	39_V	0.820	1.00
252_T	256_S	0.813	1.00
239_K	243_Q	0.805	1.00
197_S	201_K	0.801	1.00
36_L	282_L	0.801	1.00
261_I	264_Q	0.800	1.00
247_I	253_Q	0.794	1.00
186_G	189_Y	0.794	1.00
69_L	85_S	0.792	0.99
173_R	176_Y	0.792	0.99
254_Y	258_L	0.791	0.99
148_C	182_A	0.789	0.99
156_N	171_V	0.784	0.99
208_Y	226_I	0.781	0.99
65_I	69_L	0.781	0.99
188_Y	192_L	0.776	0.99
30_F	60_I	0.774	0.99
60_I	63_S	0.773	0.99
156_N	174_Y	0.773	0.99
30_F	182_A	0.772	0.99
211_L	222_L	0.772	0.99
65_I	94_L	0.767	0.99
114_Y	154_L	0.765	0.99
97_V	120_N	0.762	0.99
70_E	123_M	0.757	0.99
137_E	206_L	0.756	0.99
251_V	255_I	0.754	0.99
192_L	256_S	0.752	0.99
285_E	288_L	0.751	0.99
15_S	19_Y	0.744	0.99
73_D	190_V	0.741	0.99
225_L	238_D	0.741	0.99
246_L	249_A	0.736	0.99
70_E	130_I	0.735	0.99
84_R	87_S	0.734	0.99
23_D	79_W	0.731	0.99
268_S	272_Q	0.731	0.99
40_V	279_K	0.731	0.99
34_T	53_G	0.724	0.99
214_L	250_G	0.721	0.99
67_D	71_D	0.721	0.99
114_Y	118_Y	0.719	0.99
278_E	281_E	0.718	0.99
55_G	105_L	0.715	0.99
174_Y	283_I	0.711	0.99
18_L	93_S	0.707	0.99
55_G	115_V	0.705	0.99
236_L	240_E	0.704	0.99
181_I	266_C	0.703	0.99
227_S	231_L	0.702	0.99
86_E	127_H	0.700	0.99
206_L	210_Y	0.700	0.99
122_A	152_I	0.699	0.99
44_E	48_V	0.696	0.99
148_C	152_I	0.695	0.99
260_E	291_T	0.694	0.99
279_K	282_L	0.692	0.99
106_N	113_K	0.692	0.99
62_S	70_E	0.691	0.99
221_D	245_K	0.690	0.99
191_L	207_I	0.687	0.99
192_L	247_I	0.682	0.98
181_I	263_K	0.672	0.98
155_A	159_G	0.672	0.98
211_L	242_F	0.672	0.98
59_L	98_G	0.669	0.98
64_D	77_A	0.668	0.98
100_T	113_K	0.666	0.98
138_D	142_E	0.666	0.98
186_G	196_R	0.666	0.98
99_L	116_L	0.664	0.98
51_R	101_S	0.663	0.98
222_L	245_K	0.662	0.98
181_I	259_L	0.660	0.98
148_C	186_G	0.657	0.98
128_D	131_T	0.656	0.98
245_K	248_K	0.655	0.98
147_K	183_Q	0.653	0.98
34_T	159_G	0.651	0.98
242_F	246_L	0.651	0.98
282_L	285_E	0.651	0.98
131_T	135_K	0.651	0.98
146_L	150_S	0.650	0.98
118_Y	150_S	0.650	0.98
100_T	104_S	0.648	0.98
184_I	259_L	0.646	0.98
96_T	123_M	0.643	0.98
157_V	161_L	0.640	0.98
141_L	145_R	0.640	0.98
101_S	104_S	0.640	0.98
158_A	162_L	0.639	0.98
41_F	171_V	0.638	0.98
222_L	231_L	0.636	0.98
129_D	133_K	0.636	0.98
257_V	264_Q	0.636	0.98
121_E	145_R	0.633	0.98
235_S	240_E	0.632	0.98
96_T	119_V	0.632	0.98
177_Y	180_I	0.630	0.97
208_Y	222_L	0.627	0.97
154_L	158_A	0.625	0.97
56_I	158_A	0.625	0.97
208_Y	242_F	0.624	0.97
46_L	51_R	0.619	0.97
222_L	229_K	0.617	0.97
17_L	82_I	0.614	0.97
37_H	159_G	0.613	0.97
65_I	87_S	0.613	0.97
51_R	105_L	0.610	0.97
35_I	39_V	0.608	0.97
20_S	79_W	0.606	0.97
52_L	105_L	0.605	0.97
276_D	279_K	0.596	0.97
258_L	265_K	0.595	0.96
237_L	241_K	0.593	0.96
128_D	143_V	0.593	0.96
29_S	286_C	0.592	0.96
34_T	155_A	0.591	0.96
21_F	61_L	0.589	0.96
260_E	288_L	0.589	0.96
58_I	94_L	0.588	0.96
50_T	54_A	0.585	0.96
225_L	229_K	0.583	0.96
285_E	289_S	0.581	0.96
30_F	64_D	0.581	0.96
252_T	255_I	0.579	0.96
278_E	282_L	0.577	0.96
59_L	62_S	0.574	0.96
216_N	219_S	0.573	0.96
103_Y	113_K	0.573	0.96
225_L	230_D	0.573	0.96
27_T	186_G	0.573	0.96
197_S	200_E	0.572	0.96
172_E	176_Y	0.572	0.96
145_R	150_S	0.572	0.96
190_V	197_S	0.570	0.96
207_I	255_I	0.568	0.95
21_F	82_I	0.568	0.95
225_L	241_K	0.566	0.95
35_I	50_T	0.565	0.95
224_Y	238_D	0.565	0.95
174_Y	178_K	0.565	0.95
130_I	203_K	0.563	0.95
39_V	42_G	0.562	0.95
139_E	143_V	0.560	0.95
225_L	228_H	0.560	0.95
285_E	292_K	0.559	0.95
184_I	258_L	0.559	0.95
77_A	186_G	0.558	0.95
99_L	119_V	0.557	0.95
260_E	263_K	0.555	0.95
170_T	273_L	0.552	0.95
68_D	71_D	0.552	0.95
16_Q	20_S	0.551	0.95
14_L	17_L	0.550	0.95
129_D	204_H	0.550	0.95
32_E	289_S	0.549	0.95
69_L	83_N	0.547	0.94
250_G	254_Y	0.544	0.94
206_L	254_Y	0.544	0.94
263_K	290_Y	0.542	0.94
185_S	290_Y	0.542	0.94
99_L	115_V	0.542	0.94
230_D	237_L	0.541	0.94
141_L	184_I	0.540	0.94
219_S	226_I	0.540	0.94
62_S	95_Y	0.539	0.94
43_G	46_L	0.537	0.94
160_V	175_S	0.537	0.94
141_L	144_I	0.536	0.94
67_D	187_D	0.535	0.94
222_L	227_S	0.535	0.94
55_G	59_L	0.533	0.94
174_Y	266_C	0.531	0.93
15_S	124_Q	0.530	0.93
63_S	148_C	0.530	0.93
185_S	188_Y	0.529	0.93
13_D	131_T	0.528	0.93
73_D	83_N	0.526	0.93
214_L	249_A	0.526	0.93
115_V	158_A	0.525	0.93
96_T	116_L	0.524	0.93
99_L	102_I	0.524	0.93
137_E	141_L	0.523	0.93
264_Q	271_E	0.523	0.93
145_R	153_A	0.522	0.93
185_S	291_T	0.521	0.93
121_E	124_Q	0.520	0.93
140_S	143_V	0.520	0.93
68_D	76_H	0.520	0.93
125_G	146_L	0.520	0.93
276_D	284_K	0.520	0.93
95_Y	99_L	0.520	0.93
133_K	201_K	0.518	0.93
259_L	263_K	0.516	0.93
222_L	225_L	0.516	0.93
126_Q	191_L	0.514	0.92
184_I	262_Y	0.513	0.92
59_L	154_L	0.512	0.92
170_T	173_R	0.510	0.92
143_V	204_H	0.509	0.92
60_I	148_C	0.508	0.92
64_D	186_G	0.507	0.92
28_F	32_E	0.507	0.92
129_D	143_V	0.506	0.92
73_D	81_K	0.506	0.92
245_K	249_A	0.506	0.92
72_E	83_N	0.503	0.92
27_T	182_A	0.502	0.91
198_D	205_T	0.500	0.91
59_L	115_V	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3oyrA	2	0.9599	100	0.169	Contact Map
4jxyA	5	0.9164	100	0.175	Contact Map
1wy0A	2	0.9565	100	0.184	Contact Map
3wjkA	2	0.9431	100	0.184	Contact Map
3rmgA	2	0.9064	100	0.185	Contact Map
3mzvA	2	0.9666	100	0.185	Contact Map
3lmdA	2	0.9231	100	0.185	Contact Map
3aqbB	1	0.9532	100	0.185	Contact Map
3pkoA	2	0.9532	100	0.188	Contact Map
4lobA	2	0.9064	100	0.188	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.