GREMLIN Database
YLXP - Uncharacterized protein YlxP
UniProt: P32730 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 92 (89)
Sequences: 645 (470)
Seq/√Len: 49.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
3_G69_L2.7201.00
43_G52_S2.6651.00
27_I82_I2.5631.00
11_I14_A2.5381.00
70_Q89_T2.3191.00
7_C76_I2.2401.00
45_Q60_S2.2321.00
14_A19_E2.1441.00
11_I23_V2.1261.00
42_I54_G2.0951.00
9_C82_I2.0541.00
31_V39_I2.0281.00
42_I58_V1.9911.00
8_E50_R1.8060.99
62_R66_E1.7870.99
38_S57_A1.7000.98
3_G65_T1.6960.98
37_V72_V1.6380.98
9_C76_I1.5680.97
31_V72_V1.5620.97
54_G58_V1.5530.97
59_S65_T1.5290.97
84_R87_T1.4960.96
14_A23_V1.4720.96
44_Y52_S1.4450.96
31_V37_V1.4290.95
71_R74_A1.4240.95
42_I52_S1.4090.95
6_E52_S1.3940.95
57_A65_T1.3560.94
72_V75_F1.3360.93
28_L39_I1.3160.93
25_K29_T1.2860.92
12_Y49_Q1.1810.88
5_A69_L1.1340.86
20_K46_D1.1270.86
31_V55_I1.1270.86
10_I50_R1.1230.86
35_F75_F1.1140.85
15_G49_Q1.1090.85
2_I56_A1.0970.84
29_T33_N1.0940.84
25_K28_L1.0420.81
15_G19_E1.0300.80
77_D84_R1.0260.80
66_E89_T1.0120.79
32_Q36_N1.0050.79
55_I72_V1.0020.78
73_L87_T0.9760.76
5_A55_I0.9690.76
44_Y47_T0.9440.74
10_I83_E0.9440.74
11_I51_T0.9060.71
8_E86_I0.9010.70
14_A48_W0.8930.70
9_C51_T0.8870.69
22_A26_R0.8840.69
59_S64_Q0.8810.69
24_L51_T0.8510.66
44_Y50_R0.8480.66
66_E70_Q0.8340.64
19_E22_A0.8310.64
64_Q67_K0.8200.63
11_I19_E0.8060.62
10_I85_T0.8010.61
4_F56_A0.7980.61
15_G46_D0.7920.60
7_C84_R0.7910.60
34_K58_V0.7880.60
13_D80_P0.7850.60
38_S78_S0.7800.59
24_L28_L0.7750.59
30_R33_N0.7700.58
53_F75_F0.7550.57
46_D65_T0.7300.54
13_D27_I0.7290.54
77_D87_T0.7160.53
4_F42_I0.7120.52
51_T82_I0.7110.52
74_A86_I0.7020.51
23_V35_F0.6980.51
36_N90_E0.6970.51
26_R30_R0.6950.51
37_V59_S0.6930.50
10_I13_D0.6730.48
40_S60_S0.6700.48
29_T34_K0.6680.48
73_L77_D0.6670.48
27_I76_I0.6630.47
34_K47_T0.6540.46
13_D48_W0.6450.46
39_I55_I0.6420.45
25_K54_G0.6390.45
13_D22_A0.6380.45
63_V67_K0.6320.44
53_F69_L0.6310.44
4_F72_V0.6230.43
22_A87_T0.6070.42
38_S64_Q0.6020.41
39_I76_I0.6000.41
64_Q71_R0.5980.41
54_G74_A0.5970.41
5_A87_T0.5960.41
40_S56_A0.5850.40
28_L35_F0.5830.39
19_E32_Q0.5820.39
36_N66_E0.5800.39
15_G37_V0.5780.39
51_T68_E0.5700.38
69_L72_V0.5690.38
28_L56_A0.5690.38
32_Q38_S0.5680.38
4_F69_L0.5640.38
67_K82_I0.5550.37
25_K65_T0.5460.36
35_F71_R0.5430.36
2_I29_T0.5360.35
66_E77_D0.5330.35
4_F7_C0.5320.35
24_L90_E0.5310.34
65_T68_E0.5300.34
14_A49_Q0.5260.34
22_A25_K0.5260.34
24_L45_Q0.5250.34
79_F82_I0.5230.34
69_L89_T0.5210.34
59_S73_L0.5200.33
40_S58_V0.5160.33
31_V63_V0.5080.32
8_E48_W0.5060.32
36_N57_A0.5040.32
56_A90_E0.5020.32
51_T80_P0.5010.32
70_Q74_A0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1j27A 2 0.9891 100 0.111 Contact Map
4jj9A 3 0.6739 6 0.933 Contact Map
4bejA 2 0.4565 5.5 0.934 Contact Map
3mf7A 3 0.5761 5.4 0.934 Contact Map
2l2lA 1 0.4674 4.5 0.936 Contact Map
2oniA 4 0.8587 4.1 0.938 Contact Map
3d9wA 2 0.5978 4 0.938 Contact Map
3g13A 2 0.5109 3.9 0.939 Contact Map
3iclA 1 0.913 3.9 0.939 Contact Map
2jxuA 1 0.7391 3.7 0.939 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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