GREMLIN Database
YLXR - Uncharacterized protein YlxR
UniProt: P32728 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 91 (84)
Sequences: 959 (693)
Seq/√Len: 75.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_S36_S2.8411.00
67_Q73_Q2.7491.00
15_T56_C2.7081.00
11_K16_G2.5961.00
64_N67_Q2.4721.00
61_K83_L2.3191.00
30_S34_E2.2801.00
20_P23_E2.1501.00
15_T51_T2.1211.00
36_S43_K2.1171.00
35_I70_F1.9861.00
58_L83_L1.9471.00
9_L20_P1.8991.00
11_K18_M1.8571.00
54_K58_L1.7241.00
51_T56_C1.7161.00
59_A63_K1.6561.00
31_K36_S1.5380.99
81_E85_L1.4800.99
19_K51_T1.4730.99
14_V56_C1.4550.99
61_K79_F1.3560.98
76_D80_D1.3330.98
9_L18_M1.3330.98
29_R72_S1.3310.98
61_K80_D1.3250.98
61_K76_D1.3130.98
81_E84_E1.3010.98
54_K83_L1.2580.97
12_C56_C1.2540.97
77_Q81_E1.2520.97
67_Q74_I1.2430.97
29_R33_G1.2390.97
50_L57_I1.2300.97
54_K87_E1.2260.97
39_P52_L1.1860.96
37_V78_I1.1460.95
73_Q76_D1.1020.94
25_I82_L1.0660.93
19_K23_E1.0610.93
55_E58_L1.0500.93
57_I61_K1.0350.92
58_L62_K1.0270.92
35_I72_S0.9780.90
65_T69_Q0.9730.89
14_V57_I0.9710.89
57_I83_L0.9610.89
57_I66_L0.9370.87
39_P85_L0.9270.87
28_V36_S0.9260.87
36_S44_N0.9160.86
20_P24_L0.9060.86
80_D84_E0.8700.83
30_S44_N0.8680.83
6_K17_E0.8480.82
9_L17_E0.8470.82
75_D86_A0.8440.81
57_I86_A0.8420.81
12_C15_T0.8330.81
13_V70_F0.8310.80
15_T37_V0.8300.80
71_Q74_I0.8280.80
14_V62_K0.8120.79
19_K53_D0.8040.78
44_N50_L0.8040.78
37_V82_L0.7960.77
24_L56_C0.7870.77
35_I74_I0.7730.75
82_L86_A0.7630.74
52_L57_I0.7630.74
84_E87_E0.7590.74
29_R35_I0.7540.74
6_K22_K0.7370.72
6_K41_G0.7370.72
65_T71_Q0.7330.71
6_K27_V0.7230.70
65_T68_N0.7020.68
78_I81_E0.6960.67
83_L87_E0.6950.67
34_E43_K0.6770.65
75_D78_I0.6620.64
33_G36_S0.6590.63
25_I53_D0.6420.61
14_V19_K0.6410.61
14_V44_N0.6400.61
16_G20_P0.6290.60
78_I86_A0.6210.59
25_I52_L0.6200.59
27_V50_L0.6140.58
78_I85_L0.5980.56
7_I17_E0.5980.56
7_I20_P0.5940.55
13_V65_T0.5890.55
19_K43_K0.5850.54
46_R56_C0.5850.54
50_L60_A0.5780.53
28_V70_F0.5780.53
57_I85_L0.5770.53
52_L86_A0.5760.53
55_E59_A0.5730.53
24_L32_E0.5690.52
12_C51_T0.5690.52
33_G46_R0.5610.51
4_H81_E0.5590.51
53_D76_D0.5490.50
19_K56_C0.5410.49
30_S72_S0.5400.49
59_A65_T0.5380.48
80_D83_L0.5350.48
13_V48_A0.5350.48
8_P12_C0.5350.48
15_T65_T0.5180.46
10_R15_T0.5160.46
30_S33_G0.5140.45
14_V51_T0.5120.45
32_E36_S0.5100.45
40_T44_N0.5100.45
13_V16_G0.5090.45
15_T19_K0.5060.44
11_K72_S0.5050.44
29_R70_F0.5040.44
52_L76_D0.5030.44
44_N63_K0.5020.44
40_T55_E0.5010.44
58_L87_E0.5010.44
48_A70_F0.5000.44
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1g2rA 1 0.956 100 0.223 Contact Map
4adnA 2 0.7033 63.9 0.896 Contact Map
2yb5A 1 0.6593 50.1 0.904 Contact Map
1ovxA 2 0.4176 19.8 0.923 Contact Map
2ogfA 4 0.6044 16.2 0.926 Contact Map
2ds5A 2 0.4835 15 0.927 Contact Map
3anwA 1 0.4286 14.3 0.928 Contact Map
2i52A 5 0.5604 10.4 0.932 Contact Map
4uhqA 1 0.5055 6.9 0.937 Contact Map
1k3xA 1 0.3736 6.5 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0053 seconds.