PPOX - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PPOX - Protoporphyrinogen oxidase

UniProt:	P32397	Sequences: MSDGKKHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKKDGYIIERGPDSFLERKKSAPQLVKDLGLEHLLVNNATGQSYVLVNRTLHPMPKGAVMGIPTKIAPFVSTGLFSLSGKARAAMDFILPASKTKDDQSLGEFFRRRVGDEVVENLIEPLLSGIYAGDIDKLSLMSTFPQFYQTEQKHRSLILGMKKTRPQGSGQQLTAKKQGQFQTLSTGLQTLVEEIEKQLKLTKVYKGTKVTKLSHSGSCYSLELDNGVTLDADSVIVTAPHKAAAGMLSELPAISHLKNMHSTSVANVALGFPEGSVQMEHEGTGFVISRNSDFAITACTWTNKKWPHAAPEGKTLLRAYVGKAGDESIVDLSDNDIINIVLEDLKKVMNINGEPEMTCVTRWHESMPQYHVGHKQRIKELREALASAYPGVYMTGASFEGVGIPDCIDQGKAAVSDALTYLFS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	470 (424)
Sequences:	15481 (12577)
Seq/√Len:	610.8

ECOLI - GLF
BACSU - PPOX YOBN
HALSA - Q9HP88 Q9HPD8 Q9HP54 Q9HSE1 Q9HRU3 Q9HRN2
SULSO - Q97W24 Q97UT6 Q97YW3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
7_H	36_E	4.232	1.00
9_V	278_A	4.103	1.00
38_T	251_Y	3.784	1.00
245_L	248_T	3.729	1.00
7_H	279_D	3.718	1.00
42_A	255_K	3.684	1.00
46_V	252_K	3.494	1.00
258_K	269_E	3.459	1.00
40_V	276_L	3.126	1.00
20_A	282_I	3.124	1.00
283_V	290_A	3.102	1.00
46_V	242_E	2.939	1.00
9_V	40_V	2.795	1.00
44_P	253_G	2.777	1.00
269_E	275_T	2.751	1.00
457_G	461_V	2.708	1.00
260_S	269_E	2.699	1.00
235_Q	239_E	2.680	1.00
9_V	276_L	2.678	1.00
13_G	46_V	2.659	1.00
36_E	249_K	2.534	1.00
9_V	268_L	2.405	1.00
236_T	239_E	2.360	1.00
330_T	334_I	2.354	1.00
379_S	382_D	2.315	1.00
257_T	271_D	2.305	1.00
11_I	283_V	2.301	1.00
255_K	271_D	2.301	1.00
254_T	270_L	2.293	1.00
270_L	276_L	2.290	1.00
331_G	334_I	2.275	1.00
251_Y	274_V	2.264	1.00
8_V	35_L	2.263	1.00
40_V	251_Y	2.231	1.00
23_Y	458_K	2.227	1.00
242_E	246_K	2.199	1.00
284_T	441_T	2.179	1.00
242_E	250_V	2.177	1.00
150_Q	158_R	2.174	1.00
54_K	59_I	2.128	1.00
251_Y	254_T	2.124	1.00
11_I	285_A	2.106	1.00
280_S	439_Y	2.082	1.00
52_T	59_I	2.034	1.00
7_H	38_T	2.029	1.00
267_S	277_D	2.014	1.00
45_R	51_Q	2.002	1.00
15_I	450_I	1.999	1.00
117_K	120_P	1.990	1.00
319_P	400_E	1.955	1.00
16_T	284_T	1.946	1.00
319_P	402_E	1.933	1.00
153_G	157_R	1.930	1.00
23_Y	26_K	1.894	1.00
22_F	244_Q	1.878	1.00
40_V	278_A	1.877	1.00
240_E	243_K	1.870	1.00
384_I	404_T	1.836	1.00
27_E	465_L	1.816	1.00
260_S	267_S	1.816	1.00
19_A	454_I	1.809	1.00
267_S	275_T	1.807	1.00
6_K	38_T	1.786	1.00
257_T	269_E	1.786	1.00
262_S	267_S	1.746	1.00
385_N	389_E	1.739	1.00
254_T	272_N	1.732	1.00
282_I	464_A	1.714	1.00
381_N	385_N	1.705	1.00
23_Y	462_S	1.670	1.00
260_S	275_T	1.669	1.00
26_K	80_D	1.626	1.00
151_S	154_E	1.605	1.00
360_K	402_E	1.605	1.00
38_T	249_K	1.598	1.00
115_P	130_S	1.583	1.00
392_K	397_I	1.581	1.00
8_V	280_S	1.580	1.00
411_E	414_P	1.563	1.00
251_Y	276_L	1.559	1.00
270_L	274_V	1.545	1.00
285_A	290_A	1.543	1.00
35_L	465_L	1.525	1.00
21_A	39_L	1.520	1.00
380_D	408_R	1.509	1.00
246_K	249_K	1.493	1.00
8_V	24_M	1.492	1.00
329_G	332_F	1.459	1.00
79_K	84_E	1.453	1.00
50_I	238_V	1.445	1.00
331_G	335_S	1.442	1.00
46_V	238_V	1.436	1.00
9_V	38_T	1.429	1.00
266_Y	281_V	1.426	1.00
441_T	460_A	1.423	1.00
254_T	274_V	1.422	1.00
414_P	418_V	1.421	1.00
76_Q	80_D	1.411	1.00
58_Y	317_G	1.409	1.00
25_E	248_T	1.398	1.00
17_G	284_T	1.382	1.00
46_V	250_V	1.381	1.00
239_E	243_K	1.380	1.00
38_T	276_L	1.379	1.00
22_F	26_K	1.371	1.00
40_V	256_V	1.368	1.00
430_A	433_S	1.352	1.00
10_I	21_A	1.342	1.00
439_Y	460_A	1.342	1.00
39_L	250_V	1.341	1.00
153_G	182_D	1.327	1.00
134_R	137_M	1.324	1.00
245_L	250_V	1.320	1.00
280_S	464_A	1.318	1.00
86_L	231_S	1.316	1.00
7_H	35_L	1.314	1.00
330_T	333_V	1.314	1.00
162_D	166_E	1.309	1.00
243_K	246_K	1.309	1.00
234_L	450_I	1.307	1.00
180_D	183_K	1.307	1.00
38_T	278_A	1.303	1.00
129_L	132_K	1.289	1.00
157_R	166_E	1.281	1.00
75_P	79_K	1.274	1.00
40_V	254_T	1.271	1.00
259_L	266_Y	1.256	1.00
49_K	443_A	1.256	1.00
332_F	335_S	1.245	1.00
122_V	125_G	1.240	1.00
412_S	415_Q	1.233	1.00
278_A	281_V	1.230	1.00
261_H	266_Y	1.227	1.00
16_T	456_Q	1.226	1.00
384_I	388_L	1.219	1.00
314_V	406_V	1.217	1.00
401_P	404_T	1.216	1.00
22_F	241_I	1.214	1.00
459_A	463_D	1.209	1.00
460_A	463_D	1.206	1.00
256_V	268_L	1.202	1.00
319_P	360_K	1.201	1.00
390_D	393_K	1.191	1.00
318_F	388_L	1.189	1.00
286_P	289_A	1.186	1.00
25_E	245_L	1.186	1.00
266_Y	437_G	1.185	1.00
287_H	444_S	1.179	1.00
76_Q	458_K	1.176	1.00
125_G	128_S	1.173	1.00
25_E	37_L	1.172	1.00
54_K	57_G	1.171	1.00
73_S	458_K	1.167	1.00
317_G	403_M	1.165	1.00
318_F	401_P	1.164	1.00
316_L	388_L	1.159	1.00
84_E	231_S	1.148	1.00
16_T	441_T	1.147	1.00
411_E	419_G	1.146	1.00
13_G	39_L	1.142	1.00
54_K	235_Q	1.141	1.00
386_I	389_E	1.138	1.00
366_Y	369_K	1.126	1.00
230_L	237_L	1.124	1.00
77_L	81_L	1.124	1.00
40_V	270_L	1.124	1.00
413_M	419_G	1.122	1.00
115_P	118_I	1.122	1.00
76_Q	79_K	1.119	1.00
388_L	392_K	1.108	1.00
329_G	333_V	1.107	1.00
232_T	236_T	1.106	1.00
6_K	279_D	1.104	1.00
347_W	350_K	1.094	1.00
262_S	277_D	1.093	1.00
445_F	459_A	1.089	1.00
320_E	400_E	1.089	1.00
254_T	276_L	1.089	1.00
458_K	462_S	1.083	1.00
414_P	419_G	1.081	1.00
414_P	417_H	1.076	1.00
410_H	413_M	1.073	1.00
328_E	331_G	1.071	1.00
53_V	62_R	1.064	1.00
126_L	132_K	1.062	1.00
331_G	336_R	1.056	1.00
382_D	385_N	1.055	1.00
150_Q	154_E	1.051	1.00
265_C	277_D	1.050	1.00
262_S	265_C	1.050	1.00
23_Y	457_G	1.046	1.00
413_M	417_H	1.042	1.00
364_R	368_G	1.039	1.00
242_E	252_K	1.039	1.00
239_E	242_E	1.036	1.00
84_E	87_L	1.031	1.00
170_E	181_I	1.029	1.00
24_M	461_V	1.024	1.00
171_P	175_G	1.023	1.00
137_M	141_L	1.019	1.00
411_E	418_V	1.019	1.00
259_L	281_V	1.015	1.00
93_G	96_Y	1.013	1.00
439_Y	464_A	1.011	1.00
382_D	386_I	1.010	1.00
259_L	283_V	1.007	1.00
22_F	245_L	1.006	1.00
10_I	37_L	1.004	1.00
432_A	463_D	1.003	1.00
406_V	409_W	1.002	1.00
113_G	116_T	0.997	1.00
118_I	122_V	0.996	1.00
289_A	292_G	0.996	1.00
389_E	393_K	0.993	1.00
244_Q	247_L	0.989	1.00
23_Y	80_D	0.988	1.00
445_F	456_Q	0.988	1.00
174_S	180_D	0.987	1.00
412_S	416_Y	0.986	1.00
138_D	141_L	0.986	1.00
13_G	252_K	0.985	1.00
7_H	276_L	0.984	1.00
55_K	405_C	0.983	1.00
236_T	240_E	0.978	1.00
344_A	348_T	0.977	1.00
163_E	167_N	0.972	1.00
78_V	83_L	0.966	1.00
410_H	414_P	0.965	1.00
126_L	129_L	0.960	1.00
415_Q	418_V	0.958	1.00
112_M	115_P	0.955	1.00
418_V	421_K	0.955	1.00
113_G	117_K	0.952	1.00
15_I	50_I	0.947	1.00
415_Q	419_G	0.947	1.00
413_M	418_V	0.945	1.00
127_F	131_G	0.941	1.00
439_Y	463_D	0.936	1.00
22_F	80_D	0.936	1.00
435_Y	438_V	0.935	1.00
378_L	382_D	0.935	1.00
26_K	244_Q	0.934	1.00
74_A	454_I	0.933	1.00
35_L	38_T	0.927	1.00
128_S	131_G	0.926	1.00
7_H	277_D	0.926	1.00
329_G	334_I	0.926	1.00
342_I	347_W	0.920	1.00
52_T	235_Q	0.918	1.00
419_G	422_Q	0.918	1.00
412_S	417_H	0.915	1.00
79_K	82_G	0.915	1.00
367_V	387_V	0.911	1.00
343_T	346_T	0.910	1.00
115_P	121_F	0.909	1.00
6_K	36_E	0.905	1.00
243_K	247_L	0.900	1.00
403_M	409_W	0.898	1.00
122_V	126_L	0.898	1.00
411_E	422_Q	0.891	1.00
20_A	457_G	0.890	1.00
343_T	348_T	0.885	1.00
43_S	51_Q	0.881	1.00
135_A	139_F	0.877	1.00
411_E	416_Y	0.876	1.00
114_I	117_K	0.874	1.00
23_Y	27_E	0.873	1.00
391_L	395_M	0.873	1.00
283_V	438_V	0.872	1.00
270_L	273_G	0.871	1.00
238_V	242_E	0.871	1.00
285_A	293_M	0.870	1.00
78_V	81_L	0.870	1.00
58_Y	357_P	0.868	1.00
268_L	271_D	0.867	1.00
344_A	347_W	0.866	1.00
81_L	85_H	0.865	1.00
132_K	135_A	0.864	1.00
340_F	393_K	0.863	1.00
128_S	132_K	0.861	1.00
389_E	392_K	0.861	1.00
317_G	402_E	0.859	1.00
401_P	409_W	0.858	1.00
417_H	420_H	0.854	1.00
261_H	435_Y	0.849	1.00
167_N	171_P	0.847	1.00
261_H	437_G	0.846	1.00
107_P	113_G	0.843	1.00
175_G	178_A	0.842	1.00
361_T	364_R	0.841	1.00
6_K	9_V	0.840	1.00
83_L	247_L	0.835	1.00
191_P	194_Y	0.834	1.00
49_K	63_G	0.831	1.00
116_T	120_P	0.829	1.00
118_I	121_F	0.827	1.00
171_P	174_S	0.822	1.00
170_E	174_S	0.821	1.00
442_G	456_Q	0.821	1.00
390_D	394_V	0.819	1.00
123_S	129_L	0.815	1.00
56_D	403_M	0.815	1.00
333_V	336_R	0.814	1.00
55_K	403_M	0.813	1.00
380_D	384_I	0.810	1.00
411_E	420_H	0.809	1.00
414_P	420_H	0.808	1.00
129_L	133_A	0.808	1.00
330_T	335_S	0.806	1.00
34_P	37_L	0.806	1.00
175_G	179_G	0.802	1.00
73_S	76_Q	0.802	1.00
342_I	348_T	0.802	1.00
114_I	118_I	0.797	1.00
316_L	365_A	0.797	1.00
177_Y	184_L	0.795	1.00
453_C	457_G	0.794	1.00
21_A	245_L	0.792	1.00
25_E	249_K	0.791	1.00
136_A	140_I	0.790	1.00
92_T	95_S	0.789	1.00
157_R	162_D	0.788	1.00
371_G	374_S	0.788	1.00
343_T	347_W	0.785	1.00
39_L	245_L	0.785	1.00
53_V	405_C	0.784	1.00
58_Y	360_K	0.782	1.00
412_S	419_G	0.781	1.00
392_K	398_N	0.779	1.00
328_E	334_I	0.779	1.00
27_E	34_P	0.776	1.00
461_V	464_A	0.775	1.00
16_T	453_C	0.774	1.00
259_L	268_L	0.769	1.00
19_A	23_Y	0.766	1.00
27_E	462_S	0.762	1.00
460_A	464_A	0.761	1.00
341_A	347_W	0.759	1.00
312_A	408_R	0.759	1.00
116_T	119_A	0.758	1.00
186_L	190_F	0.758	1.00
257_T	260_S	0.758	1.00
82_G	88_V	0.758	1.00
15_I	238_V	0.755	1.00
61_E	234_L	0.753	1.00
38_T	279_D	0.753	1.00
77_L	80_D	0.751	1.00
7_H	278_A	0.751	1.00
257_T	270_L	0.751	1.00
131_G	134_R	0.751	1.00
189_T	192_Q	0.751	1.00
81_L	241_I	0.751	1.00
119_A	122_V	0.750	1.00
130_S	134_R	0.749	1.00
318_F	322_S	0.749	1.00
19_A	457_G	0.745	1.00
280_S	437_G	0.745	1.00
361_T	365_A	0.742	1.00
73_S	455_D	0.739	1.00
391_L	398_N	0.735	1.00
50_I	64_P	0.734	1.00
384_I	387_V	0.733	1.00
10_I	17_G	0.732	1.00
240_E	244_Q	0.728	1.00
187_M	190_F	0.728	1.00
185_S	188_S	0.725	1.00
111_V	115_P	0.723	1.00
6_K	35_L	0.722	1.00
27_E	35_L	0.719	1.00
131_G	135_A	0.719	1.00
96_Y	99_V	0.719	1.00
11_I	256_V	0.718	1.00
15_I	453_C	0.717	1.00
83_L	88_V	0.716	1.00
150_Q	155_F	0.716	1.00
123_S	132_K	0.716	1.00
163_E	166_E	0.715	1.00
381_N	384_I	0.715	1.00
75_P	85_H	0.714	1.00
256_V	270_L	0.713	1.00
372_D	375_I	0.713	1.00
85_H	88_V	0.712	1.00
365_A	391_L	0.712	1.00
402_E	405_C	0.711	1.00
383_I	406_V	0.711	1.00
144_S	148_D	0.710	1.00
455_D	459_A	0.710	1.00
312_A	406_V	0.707	1.00
75_P	228_Q	0.707	1.00
115_P	119_A	0.706	1.00
112_M	116_T	0.700	1.00
115_P	122_V	0.698	1.00
36_E	279_D	0.698	1.00
348_T	352_W	0.698	1.00
132_K	136_A	0.697	1.00
288_K	292_G	0.696	1.00
105_P	108_K	0.696	1.00
15_I	19_A	0.696	1.00
169_I	172_L	0.695	1.00
413_M	416_Y	0.693	1.00
285_A	289_A	0.691	1.00
136_A	139_F	0.690	1.00
94_Q	98_L	0.690	1.00
257_T	273_G	0.689	1.00
21_A	248_T	0.688	1.00
109_G	113_G	0.688	1.00
282_I	439_Y	0.687	1.00
386_I	390_D	0.684	1.00
25_E	246_K	0.684	1.00
95_S	98_L	0.682	1.00
441_T	457_G	0.682	1.00
364_R	369_K	0.680	1.00
15_I	454_I	0.680	1.00
172_L	175_G	0.679	1.00
405_C	409_W	0.679	1.00
405_C	408_R	0.676	1.00
388_L	401_P	0.676	1.00
414_P	421_K	0.676	1.00
321_G	324_Q	0.675	1.00
192_Q	195_Q	0.674	1.00
134_R	138_D	0.674	1.00
413_M	420_H	0.672	1.00
137_M	140_I	0.672	1.00
119_A	123_S	0.670	1.00
71_K	451_P	0.669	1.00
45_R	235_Q	0.667	1.00
162_D	165_V	0.666	1.00
328_E	333_V	0.666	1.00
119_A	124_T	0.663	1.00
125_G	132_K	0.663	1.00
104_H	109_G	0.663	1.00
77_L	454_I	0.662	1.00
400_E	403_M	0.661	1.00
135_A	138_D	0.661	1.00
191_P	195_Q	0.660	1.00
329_G	335_S	0.659	1.00
416_Y	419_G	0.656	1.00
35_L	279_D	0.655	1.00
133_A	140_I	0.655	1.00
282_I	460_A	0.652	1.00
22_F	81_L	0.650	1.00
64_P	234_L	0.649	1.00
428_R	431_L	0.649	1.00
384_I	406_V	0.648	1.00
187_M	191_P	0.647	1.00
123_S	126_L	0.647	1.00
127_F	132_K	0.647	1.00
143_A	146_T	0.646	1.00
95_S	105_P	0.645	1.00
152_L	156_F	0.643	1.00
127_F	130_S	0.640	1.00
41_E	252_K	0.638	1.00
40_V	268_L	0.638	1.00
429_E	433_S	0.637	1.00
119_A	125_G	0.637	1.00
18_L	245_L	0.637	1.00
230_L	236_T	0.633	1.00
106_M	109_G	0.633	1.00
412_S	418_V	0.633	1.00
287_H	291_A	0.632	1.00
342_I	345_C	0.630	1.00
404_T	408_R	0.630	1.00
461_V	465_L	0.629	1.00
312_A	315_A	0.629	1.00
341_A	344_A	0.629	1.00
172_L	177_Y	0.628	1.00
363_L	368_G	0.628	1.00
316_L	404_T	0.627	1.00
102_T	164_V	0.626	1.00
164_V	167_N	0.625	1.00
178_A	185_S	0.625	1.00
171_P	176_I	0.625	1.00
309_T	313_N	0.625	1.00
301_S	304_K	0.624	1.00
404_T	409_W	0.623	1.00
132_K	137_M	0.623	1.00
50_I	234_L	0.622	1.00
18_L	238_V	0.622	1.00
188_S	191_P	0.622	1.00
111_V	114_I	0.621	1.00
181_I	184_L	0.620	1.00
9_V	281_V	0.619	1.00
82_G	85_H	0.619	1.00
35_L	280_S	0.619	1.00
428_R	446_E	0.618	1.00
82_G	87_L	0.616	1.00
78_V	230_L	0.615	1.00
133_A	139_F	0.612	1.00
177_Y	189_T	0.612	1.00
418_V	422_Q	0.610	1.00
15_I	241_I	0.608	1.00
117_K	121_F	0.608	1.00
143_A	147_K	0.607	1.00
281_V	437_G	0.607	1.00
265_C	436_P	0.606	1.00
317_G	360_K	0.606	1.00
356_A	359_G	0.605	1.00
58_Y	402_E	0.604	1.00
385_N	388_L	0.604	1.00
133_A	136_A	0.604	1.00
412_S	422_Q	0.600	1.00
385_N	404_T	0.600	1.00
20_A	460_A	0.600	1.00
286_P	444_S	0.599	1.00
76_Q	81_L	0.599	1.00
303_L	306_M	0.598	1.00
154_E	157_R	0.596	1.00
306_M	309_T	0.596	1.00
148_D	151_S	0.595	1.00
416_Y	420_H	0.594	1.00
19_A	241_I	0.594	1.00
344_A	349_N	0.589	1.00
287_H	303_L	0.589	1.00
187_M	193_F	0.588	1.00
265_C	279_D	0.588	1.00
404_T	407_T	0.587	1.00
415_Q	420_H	0.587	1.00
18_L	39_L	0.587	1.00
24_M	464_A	0.585	1.00
126_L	130_S	0.585	1.00
392_K	399_G	0.583	1.00
74_A	450_I	0.581	1.00
383_I	387_V	0.581	1.00
125_G	136_A	0.580	1.00
119_A	126_L	0.580	1.00
395_M	398_N	0.579	1.00
268_L	281_V	0.578	1.00
105_P	109_G	0.578	1.00
75_P	78_V	0.577	1.00
177_Y	181_I	0.577	1.00
316_L	401_P	0.577	1.00
52_T	61_E	0.575	1.00
6_K	280_S	0.574	1.00
61_E	66_S	0.573	1.00
190_F	194_Y	0.573	1.00
65_D	364_R	0.573	1.00
412_S	421_K	0.573	1.00
174_S	181_I	0.571	1.00
388_L	404_T	0.570	1.00
125_G	129_L	0.570	1.00
318_F	323_V	0.570	1.00
179_G	183_K	0.569	1.00
340_F	390_D	0.569	1.00
81_L	86_L	0.568	1.00
50_I	450_I	0.567	1.00
129_L	134_R	0.567	1.00
459_A	462_S	0.567	1.00
380_D	383_I	0.566	1.00
120_P	123_S	0.564	1.00
411_E	415_Q	0.563	1.00
123_S	127_F	0.563	1.00
184_L	188_S	0.563	1.00
112_M	130_S	0.561	1.00
184_L	189_T	0.561	1.00
189_T	195_Q	0.561	1.00
280_S	283_V	0.561	1.00
10_I	282_I	0.561	1.00
186_L	189_T	0.560	1.00
64_P	450_I	0.560	1.00
51_Q	407_T	0.559	1.00
417_H	422_Q	0.559	1.00
84_E	88_V	0.558	1.00
311_V	315_A	0.558	1.00
60_I	362_L	0.555	1.00
166_E	170_E	0.555	1.00
410_H	418_V	0.554	1.00
375_I	378_L	0.552	1.00
261_H	436_P	0.552	1.00
92_T	98_L	0.550	0.99
289_A	293_M	0.550	0.99
360_K	364_R	0.549	0.99
74_A	78_V	0.548	0.99
342_I	346_T	0.548	0.99
283_V	440_M	0.548	0.99
94_Q	99_V	0.547	0.99
413_M	422_Q	0.546	0.99
39_L	46_V	0.546	0.99
314_V	317_G	0.545	0.99
130_S	133_A	0.545	0.99
174_S	177_Y	0.544	0.99
114_I	121_F	0.543	0.99
332_F	336_R	0.543	0.99
356_A	360_K	0.542	0.99
302_H	306_M	0.542	0.99
6_K	249_K	0.541	0.99
348_T	351_K	0.541	0.99
314_V	318_F	0.540	0.99
341_A	349_N	0.540	0.99
92_T	97_V	0.539	0.99
97_V	105_P	0.539	0.99
346_T	351_K	0.539	0.99
349_N	361_T	0.537	0.99
242_E	248_T	0.537	0.99
174_S	178_A	0.537	0.99
328_E	332_F	0.536	0.99
180_D	185_S	0.532	0.99
164_V	171_P	0.532	0.99
132_K	138_D	0.531	0.99
290_A	294_L	0.530	0.99
373_E	376_V	0.528	0.99
189_T	193_F	0.527	0.99
410_H	415_Q	0.526	0.99
188_S	192_Q	0.523	0.99
258_K	295_S	0.522	0.99
94_Q	97_V	0.521	0.99
122_V	127_F	0.521	0.99
23_Y	77_L	0.521	0.99
73_S	454_I	0.520	0.99
362_L	368_G	0.519	0.99
261_H	438_V	0.517	0.99
160_V	169_I	0.517	0.99
72_K	76_Q	0.516	0.99
171_P	177_Y	0.515	0.99
147_K	150_Q	0.515	0.99
155_F	186_L	0.515	0.99
80_D	83_L	0.515	0.99
417_H	421_K	0.513	0.99
229_T	234_L	0.513	0.99
287_H	306_M	0.513	0.99
328_E	335_S	0.513	0.99
103_L	107_P	0.513	0.99
344_A	351_K	0.513	0.99
372_D	376_V	0.512	0.99
132_K	140_I	0.511	0.99
131_G	138_D	0.511	0.99
282_I	441_T	0.510	0.99
177_Y	180_D	0.510	0.99
73_S	451_P	0.509	0.99
37_L	245_L	0.507	0.99
51_Q	62_R	0.505	0.99
172_L	176_I	0.503	0.99
175_G	180_D	0.501	0.99
365_A	369_K	0.501	0.99
380_D	406_V	0.500	0.99
292_G	304_K	0.500	0.99
149_D	154_E	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3i6dA	1	0.8787	100	0.285	Contact Map
3lovA	1	0.9447	100	0.319	Contact Map
2ivdA	1	0.9383	100	0.332	Contact Map
1sezA	3	0.9404	100	0.34	Contact Map
4i59A	1	0.9043	100	0.366	Contact Map
2yg5A	2	0.9085	100	0.367	Contact Map
3nksA	2	0.934	100	0.39	Contact Map
1s3eA	2	0.9128	100	0.39	Contact Map
4dsgA	1	0.9213	100	0.421	Contact Map
2vvmA	2	0.9021	100	0.422	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0122 seconds.