PURA - BACSU - GREMLIN Contacts

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PURA - Adenylosuccinate synthetase

UniProt:	P29726	Sequences: MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIKFDGITYKLHLIPSGIFYKDKTCVIGNGMVVDPKALVTELAYLHERNVSTDNLRISNRAHVILPYHLKLDEVEEERKGANKIGTTKKGIGPAYMDKAARIGIRIADLLDRDAFAEKLERNLEEKNRLLEKMYETEGFKLEDILDEYYEYGQQIKKYVCDTSVVLNDALDEGRRVLFEGAQGVMLDIDQGTYPFVTSSNPVAAVSQSVLVSARPKIKHVVGVSKAYTTRVGDGPFPTELKDEIGDQIREVGREYGTTTGRPPRVGWFDSVVVRHARRVSGITDLSLNSIDVLAGIETLKICVRYRYKGEIIEEFPASLKALAECEPVYEEMPGWTEDITGAKSLSELPENARHYLERVSQLTGIPLSIFSVGPDRSQTNVLRSVYRAN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	430 (421)
Sequences:	3002 (1509)
Seq/√Len:	73.5

ECOLI - PURA
BACSU - PURA
HALSA - PURA
SULSO - Q980P5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
339_T	372_E	6.222	1.00
347_R	367_E	5.921	1.00
53_H	299_T	5.450	1.00
338_E	377_T	4.338	1.00
84_A	195_Q	3.722	1.00
391_E	395_H	3.720	1.00
385_S	388_E	3.623	1.00
51_K	298_T	3.396	1.00
349_K	365_E	3.352	1.00
371_E	399_R	3.349	1.00
48_I	89_R	3.180	1.00
386_L	394_R	3.131	1.00
328_L	397_L	3.086	1.00
399_R	403_L	3.022	1.00
290_R	303_P	2.962	1.00
287_D	291_E	2.923	1.00
84_A	88_E	2.828	1.00
339_T	374_P	2.728	1.00
288_Q	337_I	2.709	1.00
77_K	188_E	2.699	1.00
309_F	314_V	2.690	1.00
392_N	395_H	2.661	1.00
342_I	399_R	2.581	1.00
311_S	403_L	2.568	1.00
342_I	373_M	2.516	1.00
341_K	372_E	2.499	1.00
260_H	325_D	2.451	1.00
288_Q	292_V	2.440	1.00
114_E	129_K	2.431	1.00
28_E	215_R	2.403	1.00
181_K	184_D	2.399	1.00
75_D	110_L	2.347	1.00
336_G	378_E	2.344	1.00
157_A	161_E	2.331	1.00
29_V	210_A	2.254	1.00
386_L	398_E	2.246	1.00
347_R	352_I	2.219	1.00
335_A	380_I	2.206	1.00
104_V	147_I	2.206	1.00
108_Y	163_N	2.174	1.00
183_E	187_D	2.142	1.00
151_L	200_V	2.126	1.00
124_K	274_D	2.122	1.00
291_E	296_Y	2.119	1.00
348_Y	366_C	2.091	1.00
326_L	404_T	2.078	1.00
226_M	313_V	2.078	1.00
31_A	251_L	2.024	1.00
68_I	72_M	2.016	1.00
74_V	102_A	2.010	1.00
209_D	213_E	2.008	1.00
348_Y	353_I	1.976	1.00
325_D	409_S	1.946	1.00
374_P	392_N	1.942	1.00
399_R	402_Q	1.928	1.00
172_E	179_G	1.898	1.00
97_R	201_C	1.874	1.00
391_E	394_R	1.856	1.00
97_R	206_V	1.852	1.00
348_Y	365_E	1.829	1.00
342_I	403_L	1.823	1.00
394_R	398_E	1.820	1.00
373_M	399_R	1.806	1.00
80_V	195_Q	1.769	1.00
212_D	405_G	1.721	1.00
9_T	323_I	1.703	1.00
336_G	377_T	1.685	1.00
395_H	398_E	1.673	1.00
383_A	388_E	1.653	1.00
74_V	79_L	1.651	1.00
182_L	186_L	1.651	1.00
309_F	400_V	1.650	1.00
194_Q	197_K	1.632	1.00
398_E	423_L	1.631	1.00
147_I	200_V	1.627	1.00
345_R	352_I	1.622	0.99
184_D	188_E	1.620	0.99
292_V	336_G	1.619	0.99
374_P	395_H	1.608	0.99
84_A	87_H	1.608	0.99
378_E	392_N	1.607	0.99
401_S	423_L	1.577	0.99
74_V	147_I	1.573	0.99
160_L	182_L	1.570	0.99
37_N	75_D	1.566	0.99
290_R	296_Y	1.564	0.99
68_I	74_V	1.556	0.99
47_G	416_D	1.539	0.99
156_F	160_L	1.531	0.99
45_F	60_F	1.523	0.99
65_T	97_R	1.519	0.99
384_K	388_E	1.514	0.99
161_E	182_L	1.506	0.99
77_K	192_Y	1.502	0.99
157_A	186_L	1.501	0.99
37_N	105_I	1.500	0.99
153_R	190_Y	1.481	0.99
37_N	78_A	1.469	0.99
208_N	212_D	1.455	0.99
103_H	144_G	1.455	0.99
343_C	368_P	1.445	0.99
398_E	401_S	1.442	0.99
151_L	197_K	1.442	0.99
397_L	408_L	1.440	0.99
211_L	217_V	1.439	0.99
386_L	423_L	1.435	0.99
79_L	83_L	1.430	0.99
335_A	379_D	1.429	0.99
5_V	247_S	1.429	0.99
283_D	286_G	1.424	0.99
318_R	323_I	1.417	0.99
286_G	306_V	1.395	0.98
79_L	96_L	1.394	0.98
344_V	352_I	1.389	0.98
3_S	219_F	1.388	0.98
398_E	402_Q	1.385	0.98
102_A	147_I	1.382	0.98
156_F	189_Y	1.370	0.98
201_C	206_V	1.367	0.98
348_Y	362_A	1.362	0.98
67_V	203_T	1.361	0.98
225_V	321_S	1.342	0.98
137_M	141_A	1.336	0.98
359_S	362_A	1.334	0.98
70_N	231_Q	1.328	0.98
186_L	190_Y	1.325	0.98
265_S	314_V	1.324	0.98
219_F	253_S	1.322	0.98
371_E	403_L	1.308	0.98
384_K	418_S	1.295	0.97
77_K	81_T	1.292	0.97
282_K	285_I	1.288	0.97
76_P	196_I	1.282	0.97
187_D	191_E	1.269	0.97
281_L	286_G	1.266	0.97
318_R	406_I	1.256	0.97
29_V	207_L	1.248	0.97
335_A	378_E	1.239	0.97
256_P	324_T	1.234	0.97
208_N	257_K	1.222	0.96
311_S	399_R	1.221	0.96
3_S	211_L	1.217	0.96
210_A	215_R	1.215	0.96
118_E	177_T	1.209	0.96
157_A	182_L	1.206	0.96
341_K	370_Y	1.206	0.96
256_P	322_G	1.205	0.96
413_V	419_Q	1.200	0.96
352_I	367_E	1.163	0.95
29_V	206_V	1.163	0.95
356_F	363_L	1.159	0.95
30_I	64_K	1.153	0.95
384_K	419_Q	1.150	0.95
157_A	183_E	1.149	0.95
21_D	417_R	1.142	0.95
33_Y	242_P	1.139	0.95
311_S	342_I	1.134	0.95
344_V	371_E	1.123	0.94
208_N	319_R	1.122	0.94
153_R	157_A	1.121	0.94
335_A	377_T	1.114	0.94
160_L	186_L	1.113	0.94
85_Y	88_E	1.111	0.94
161_E	165_E	1.110	0.94
212_D	257_K	1.108	0.94
65_T	206_V	1.106	0.94
400_V	408_L	1.101	0.94
155_A	159_K	1.099	0.94
204_S	319_R	1.095	0.93
381_T	419_Q	1.094	0.93
312_V	345_R	1.090	0.93
118_E	129_K	1.085	0.93
348_Y	351_E	1.085	0.93
287_D	303_P	1.083	0.93
145_I	156_F	1.081	0.93
205_V	319_R	1.079	0.93
80_V	196_I	1.073	0.93
207_L	217_V	1.073	0.93
152_D	361_K	1.069	0.93
111_K	114_E	1.067	0.93
8_G	14_E	1.057	0.92
347_R	350_G	1.057	0.92
100_N	358_A	1.050	0.92
106_L	189_Y	1.046	0.92
187_D	190_Y	1.038	0.92
352_I	369_V	1.029	0.91
225_V	317_A	1.028	0.91
254_A	322_G	1.027	0.91
25_E	61_Y	1.024	0.91
241_N	249_S	1.020	0.91
101_R	358_A	1.012	0.90
98_I	147_I	1.010	0.90
74_V	98_I	1.006	0.90
383_A	386_L	0.997	0.90
284_E	287_D	0.991	0.90
373_M	395_H	0.982	0.89
288_Q	291_E	0.982	0.89
211_L	253_S	0.982	0.89
311_S	400_V	0.978	0.89
287_D	290_R	0.978	0.89
401_S	408_L	0.975	0.89
205_V	209_D	0.971	0.89
311_S	314_V	0.968	0.88
411_F	421_N	0.961	0.88
269_T	313_V	0.961	0.88
291_E	294_R	0.959	0.88
260_H	409_S	0.957	0.88
309_F	404_T	0.955	0.88
285_I	337_I	0.950	0.87
207_L	251_L	0.947	0.87
157_A	190_Y	0.944	0.87
210_A	213_E	0.939	0.87
164_L	168_N	0.938	0.87
105_I	135_A	0.936	0.87
317_A	321_S	0.934	0.87
280_E	305_R	0.932	0.86
189_Y	192_Y	0.929	0.86
248_Q	255_R	0.922	0.86
139_K	230_D	0.922	0.86
289_I	329_N	0.919	0.86
223_Q	227_L	0.919	0.86
115_V	177_T	0.919	0.86
285_I	288_Q	0.918	0.86
193_G	197_K	0.917	0.86
115_V	171_L	0.905	0.85
158_E	162_R	0.904	0.85
62_K	95_N	0.900	0.84
226_M	316_H	0.899	0.84
270_T	330_S	0.898	0.84
362_A	365_E	0.897	0.84
263_G	323_I	0.896	0.84
331_I	393_A	0.894	0.84
203_T	206_V	0.894	0.84
245_A	249_S	0.893	0.84
382_G	413_V	0.888	0.84
197_K	200_V	0.886	0.84
137_M	143_I	0.883	0.83
123_N	158_E	0.881	0.83
111_K	180_F	0.880	0.83
79_L	199_Y	0.880	0.83
180_F	185_I	0.878	0.83
381_T	413_V	0.874	0.83
205_V	355_E	0.872	0.83
5_V	258_I	0.871	0.82
123_N	236_F	0.871	0.82
227_L	271_R	0.869	0.82
85_Y	89_R	0.868	0.82
384_K	413_V	0.865	0.82
410_I	420_T	0.864	0.82
191_E	194_Q	0.862	0.82
189_Y	193_G	0.858	0.82
169_R	174_M	0.857	0.81
209_D	354_E	0.854	0.81
87_H	195_Q	0.854	0.81
42_T	49_T	0.844	0.80
416_D	419_Q	0.838	0.80
67_V	206_V	0.836	0.80
285_I	289_I	0.834	0.80
379_D	413_V	0.826	0.79
353_I	366_C	0.824	0.79
397_L	411_F	0.823	0.79
99_S	203_T	0.821	0.79
204_S	231_Q	0.818	0.78
49_T	294_R	0.817	0.78
120_K	162_R	0.813	0.78
219_F	251_L	0.812	0.78
29_V	65_T	0.811	0.78
260_H	324_T	0.809	0.78
127_T	133_G	0.809	0.78
379_D	382_G	0.809	0.78
147_I	196_I	0.807	0.77
44_K	49_T	0.805	0.77
46_D	418_S	0.804	0.77
107_P	188_E	0.802	0.77
245_A	254_A	0.801	0.77
169_R	173_K	0.800	0.77
148_A	358_A	0.797	0.77
314_V	404_T	0.794	0.76
111_K	177_T	0.792	0.76
347_R	369_V	0.792	0.76
86_L	91_V	0.792	0.76
243_V	246_V	0.791	0.76
363_L	366_C	0.791	0.76
289_I	330_S	0.790	0.76
54_L	72_M	0.786	0.76
153_R	186_L	0.786	0.76
284_E	288_Q	0.786	0.76
386_L	397_L	0.785	0.75
19_I	410_I	0.785	0.75
111_K	115_V	0.785	0.75
164_L	180_F	0.780	0.75
76_P	80_V	0.780	0.75
173_K	176_E	0.779	0.75
325_D	407_P	0.779	0.75
243_V	249_S	0.778	0.75
67_V	201_C	0.777	0.75
140_A	229_I	0.777	0.75
397_L	423_L	0.772	0.74
414_G	419_Q	0.771	0.74
337_I	340_L	0.770	0.74
395_H	402_Q	0.770	0.74
75_D	78_A	0.770	0.74
397_L	401_S	0.770	0.74
103_H	135_A	0.769	0.74
55_I	224_G	0.769	0.74
296_Y	303_P	0.764	0.73
33_Y	246_V	0.764	0.73
34_Q	224_G	0.763	0.73
279_T	370_Y	0.763	0.73
340_L	377_T	0.760	0.73
139_K	146_R	0.759	0.73
316_H	319_R	0.759	0.73
6_V	27_A	0.756	0.73
55_I	86_L	0.755	0.73
315_R	403_L	0.753	0.72
222_A	227_L	0.753	0.72
115_V	129_K	0.751	0.72
70_N	250_V	0.750	0.72
70_N	241_N	0.749	0.72
387_S	394_R	0.749	0.72
49_T	298_T	0.748	0.72
265_S	326_L	0.748	0.72
217_V	253_S	0.746	0.72
29_V	67_V	0.744	0.71
81_T	85_Y	0.742	0.71
53_H	85_Y	0.741	0.71
100_N	200_V	0.741	0.71
32_R	222_A	0.740	0.71
383_A	394_R	0.738	0.71
203_T	207_L	0.737	0.71
63_D	92_S	0.736	0.71
244_A	248_Q	0.731	0.70
3_S	253_S	0.730	0.70
223_Q	271_R	0.728	0.70
291_E	303_P	0.726	0.70
145_I	163_N	0.725	0.69
281_L	285_I	0.725	0.69
233_T	271_R	0.725	0.69
73_V	136_Y	0.723	0.69
80_V	192_Y	0.722	0.69
28_E	216_R	0.722	0.69
323_I	406_I	0.722	0.69
188_E	191_E	0.721	0.69
87_H	92_S	0.720	0.69
268_Y	333_V	0.719	0.69
87_H	93_T	0.719	0.69
353_I	362_A	0.718	0.69
59_I	66_C	0.718	0.69
330_S	333_V	0.716	0.69
83_L	93_T	0.710	0.68
80_V	84_A	0.710	0.68
327_S	410_I	0.710	0.68
108_Y	167_K	0.708	0.68
373_M	403_L	0.707	0.68
345_R	369_V	0.706	0.67
191_E	195_Q	0.704	0.67
78_A	105_I	0.704	0.67
265_S	328_L	0.703	0.67
373_M	392_N	0.703	0.67
352_I	371_E	0.702	0.67
138_D	167_K	0.700	0.67
270_T	306_V	0.699	0.67
292_V	337_I	0.699	0.67
53_H	78_A	0.699	0.67
47_G	418_S	0.698	0.67
50_Y	89_R	0.697	0.66
293_G	333_V	0.695	0.66
340_L	396_Y	0.694	0.66
68_I	79_L	0.693	0.66
110_L	114_E	0.693	0.66
190_Y	193_G	0.692	0.66
100_N	148_A	0.691	0.66
154_D	158_E	0.691	0.66
66_C	298_T	0.691	0.66
7_V	247_S	0.688	0.65
61_Y	64_K	0.687	0.65
111_K	129_K	0.686	0.65
159_K	162_R	0.685	0.65
336_G	340_L	0.684	0.65
347_R	351_E	0.681	0.65
116_E	137_M	0.681	0.65
62_K	92_S	0.680	0.65
315_R	354_E	0.679	0.64
222_A	271_R	0.679	0.64
4_V	262_V	0.678	0.64
219_F	247_S	0.678	0.64
9_T	265_S	0.677	0.64
4_V	27_A	0.676	0.64
281_L	306_V	0.676	0.64
112_L	171_L	0.674	0.64
164_L	182_L	0.673	0.64
133_G	142_R	0.671	0.64
360_L	364_A	0.671	0.64
246_V	250_V	0.668	0.63
83_L	199_Y	0.667	0.63
67_V	207_L	0.664	0.63
371_E	395_H	0.664	0.63
371_E	374_P	0.663	0.63
29_V	215_R	0.662	0.62
309_F	403_L	0.661	0.62
92_S	95_N	0.660	0.62
80_V	83_L	0.659	0.62
168_N	179_G	0.658	0.62
184_D	187_D	0.654	0.62
51_K	66_C	0.653	0.61
154_D	157_A	0.651	0.61
295_E	304_P	0.650	0.61
34_Q	242_P	0.649	0.61
288_Q	336_G	0.648	0.61
262_V	325_D	0.647	0.61
37_N	413_V	0.646	0.61
172_E	175_Y	0.646	0.61
379_D	419_Q	0.644	0.60
190_Y	194_Q	0.643	0.60
227_L	233_T	0.643	0.60
293_G	306_V	0.642	0.60
20_T	265_S	0.641	0.60
29_V	217_V	0.641	0.60
326_L	397_L	0.641	0.60
144_G	234_Y	0.640	0.60
59_I	96_L	0.639	0.60
55_I	59_I	0.639	0.60
149_D	159_K	0.638	0.60
127_T	237_V	0.638	0.60
226_M	356_F	0.637	0.60
101_R	148_A	0.637	0.60
7_V	244_A	0.636	0.59
80_V	98_I	0.636	0.59
9_T	263_G	0.634	0.59
340_L	373_M	0.633	0.59
100_N	202_D	0.633	0.59
103_H	146_R	0.632	0.59
345_R	354_E	0.628	0.58
188_E	192_Y	0.627	0.58
284_E	338_E	0.627	0.58
261_V	323_I	0.626	0.58
31_A	69_G	0.625	0.58
37_N	290_R	0.625	0.58
211_L	257_K	0.624	0.58
208_N	254_A	0.624	0.58
155_A	361_K	0.620	0.57
342_I	400_V	0.618	0.57
168_N	176_E	0.617	0.57
110_L	188_E	0.617	0.57
380_I	393_A	0.617	0.57
171_L	177_T	0.617	0.57
127_T	142_R	0.616	0.57
412_S	420_T	0.616	0.57
205_V	354_E	0.612	0.56
6_V	120_K	0.610	0.56
5_V	244_A	0.609	0.56
206_V	210_A	0.609	0.56
410_I	422_V	0.608	0.56
22_F	412_S	0.607	0.56
33_Y	412_S	0.603	0.55
19_I	412_S	0.601	0.55
52_L	59_I	0.600	0.55
81_T	84_A	0.598	0.55
233_T	269_T	0.597	0.55
148_A	200_V	0.597	0.55
109_H	138_D	0.597	0.55
70_N	230_D	0.596	0.55
69_G	250_V	0.595	0.54
119_R	169_R	0.593	0.54
168_N	175_Y	0.593	0.54
404_T	408_L	0.592	0.54
50_Y	298_T	0.591	0.54
236_F	274_D	0.591	0.54
389_L	393_A	0.590	0.54
342_I	402_Q	0.587	0.53
361_K	364_A	0.584	0.53
380_I	413_V	0.584	0.53
100_N	359_S	0.584	0.53
109_H	221_G	0.582	0.53
408_L	411_F	0.582	0.53
34_Q	52_L	0.580	0.53
326_L	400_V	0.580	0.53
344_V	347_R	0.579	0.52
121_G	274_D	0.579	0.52
361_K	365_E	0.579	0.52
34_Q	109_H	0.578	0.52
130_K	299_T	0.578	0.52
53_H	81_T	0.577	0.52
19_I	327_S	0.577	0.52
312_V	356_F	0.577	0.52
311_S	404_T	0.576	0.52
125_I	142_R	0.575	0.52
53_H	298_T	0.575	0.52
205_V	208_N	0.575	0.52
396_Y	400_V	0.574	0.52
289_I	340_L	0.573	0.52
351_E	367_E	0.573	0.52
155_A	158_E	0.572	0.52
181_K	190_Y	0.572	0.52
307_G	310_D	0.572	0.52
335_A	413_V	0.572	0.52
115_V	118_E	0.571	0.51
295_E	302_R	0.571	0.51
168_N	180_F	0.569	0.51
100_N	151_L	0.569	0.51
162_R	165_E	0.566	0.51
109_H	135_A	0.566	0.51
391_E	398_E	0.565	0.51
365_E	381_T	0.565	0.51
309_F	342_I	0.565	0.51
77_K	189_Y	0.564	0.51
124_K	129_K	0.564	0.51
24_S	27_A	0.563	0.50
9_T	224_G	0.563	0.50
413_V	420_T	0.563	0.50
9_T	314_V	0.563	0.50
294_R	303_P	0.561	0.50
258_I	261_V	0.561	0.50
342_I	371_E	0.561	0.50
335_A	381_T	0.560	0.50
37_N	167_K	0.560	0.50
3_S	217_V	0.559	0.50
55_I	277_F	0.558	0.50
140_A	143_I	0.558	0.50
10_Q	142_R	0.558	0.50
24_S	61_Y	0.558	0.50
45_F	48_I	0.558	0.50
224_G	412_S	0.556	0.50
178_E	181_K	0.556	0.50
343_C	370_Y	0.555	0.49
349_K	359_S	0.554	0.49
230_D	241_N	0.553	0.49
339_T	395_H	0.551	0.49
123_N	162_R	0.550	0.49
268_Y	293_G	0.550	0.49
367_E	371_E	0.550	0.49
107_P	185_I	0.550	0.49
61_Y	137_M	0.549	0.49
64_K	199_Y	0.549	0.49
12_G	16_K	0.549	0.49
347_R	371_E	0.548	0.49
161_E	187_D	0.545	0.48
67_V	97_R	0.544	0.48
116_E	166_E	0.543	0.48
63_D	95_N	0.543	0.48
43_I	50_Y	0.541	0.48
386_L	411_F	0.541	0.48
384_K	421_N	0.541	0.48
70_N	99_S	0.539	0.47
110_L	130_K	0.539	0.47
211_L	288_Q	0.538	0.47
54_L	73_V	0.538	0.47
65_T	215_R	0.538	0.47
12_G	15_G	0.537	0.47
290_R	313_V	0.537	0.47
272_V	302_R	0.534	0.47
330_S	334_L	0.534	0.47
81_T	88_E	0.533	0.47
53_H	130_K	0.533	0.47
318_R	404_T	0.532	0.47
106_L	163_N	0.532	0.47
383_A	423_L	0.532	0.47
393_A	413_V	0.531	0.46
148_A	359_S	0.531	0.46
166_E	170_L	0.530	0.46
165_E	169_R	0.530	0.46
59_I	91_V	0.529	0.46
383_A	402_Q	0.528	0.46
44_K	416_D	0.527	0.46
278_P	366_C	0.526	0.46
209_D	355_E	0.526	0.46
20_T	43_I	0.526	0.46
25_E	394_R	0.526	0.46
248_Q	253_S	0.526	0.46
120_K	364_A	0.525	0.46
395_H	399_R	0.523	0.45
281_L	308_W	0.523	0.45
67_V	148_A	0.523	0.45
272_V	300_T	0.523	0.45
43_I	243_V	0.521	0.45
154_D	352_I	0.520	0.45
264_V	329_N	0.520	0.45
37_N	110_L	0.519	0.45
6_V	78_A	0.518	0.45
143_I	166_E	0.518	0.45
32_R	109_H	0.518	0.45
133_G	271_R	0.517	0.45
8_G	12_G	0.517	0.45
266_K	295_E	0.517	0.45
192_Y	196_I	0.517	0.45
152_D	155_A	0.515	0.44
151_L	193_G	0.515	0.44
19_I	22_F	0.515	0.44
279_T	343_C	0.515	0.44
195_Q	198_K	0.515	0.44
206_V	209_D	0.514	0.44
256_P	261_V	0.514	0.44
243_V	248_Q	0.514	0.44
248_Q	258_I	0.514	0.44
77_K	191_E	0.513	0.44
68_I	96_L	0.513	0.44
37_N	135_A	0.512	0.44
34_Q	221_G	0.512	0.44
202_D	316_H	0.512	0.44
37_N	121_G	0.512	0.44
128_T	134_P	0.510	0.44
114_E	118_E	0.510	0.44
270_T	329_N	0.509	0.44
167_K	242_P	0.508	0.44
34_Q	57_S	0.508	0.44
253_S	257_K	0.508	0.44
401_S	407_P	0.508	0.44
20_T	30_I	0.507	0.43
6_V	23_L	0.507	0.43
43_I	49_T	0.507	0.43
75_D	107_P	0.506	0.43
160_L	185_I	0.506	0.43
172_E	178_E	0.505	0.43
237_V	271_R	0.505	0.43
152_D	359_S	0.505	0.43
59_I	93_T	0.504	0.43
286_G	330_S	0.504	0.43
164_L	181_K	0.504	0.43
104_V	145_I	0.504	0.43
43_I	51_K	0.504	0.43
222_A	233_T	0.504	0.43
145_I	149_D	0.503	0.43
243_V	356_F	0.503	0.43
248_Q	251_L	0.503	0.43
266_K	272_V	0.502	0.43
380_I	389_L	0.502	0.43
158_E	161_E	0.502	0.43
88_E	216_R	0.501	0.43
248_Q	321_S	0.500	0.43
76_P	104_V	0.500	0.43
326_L	408_L	0.500	0.43
137_M	166_E	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4m9dA	2	0.9953	100	0.004	Contact Map
3hidA	2	0.9791	100	0.008	Contact Map
3ue9A	2	0.9721	100	0.009	Contact Map
1p9bA	2	0.9698	100	0.024	Contact Map
2v40A	2	0.9558	100	0.024	Contact Map
3r7tA	4	0.9465	100	0.028	Contact Map
1dj2A	2	0.9814	100	0.03	Contact Map
2d7uA	2	0.7419	100	0.203	Contact Map
1f8mA	4	0.6349	42.5	0.98	Contact Map
3dfzA	2	0.4116	26.6	0.982	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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