GREMLIN Database
SUBV - Minor extracellular protease vpr
UniProt: P29141 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 806 (626)
Sequences: 2327 (1801)
Seq/√Len: 72.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
320_S537_S5.3411.00
421_A426_A5.1431.00
185_V241_V4.7131.00
345_A487_A4.6191.00
543_A588_A4.1821.00
262_L268_G4.1511.00
344_G506_S4.0801.00
143_D320_S3.8861.00
238_A258_A3.8081.00
320_S536_A3.8051.00
206_Y210_D3.7531.00
606_S612_K3.6241.00
188_I261_V3.5351.00
516_I528_G3.5201.00
410_G417_K3.3581.00
608_G612_K3.3491.00
186_A285_A3.2931.00
486_V506_S3.0701.00
606_S611_L3.0631.00
281_V315_V3.0191.00
605_Y608_G2.9741.00
345_A489_F2.9721.00
657_P660_Q2.9591.00
409_R433_N2.8771.00
487_A510_V2.8561.00
137_N271_E2.8521.00
179_T253_D2.8461.00
626_E661_T2.8141.00
608_G611_L2.7341.00
316_V341_I2.7281.00
453_L461_L2.6301.00
181_K253_D2.6191.00
634_S655_V2.5971.00
605_Y612_K2.5391.00
420_N423_K2.5081.00
207_K210_D2.5031.00
540_I588_A2.5001.00
229_E232_D2.4971.00
548_K559_I2.4961.00
409_R414_F2.4841.00
261_V276_G2.4691.00
543_A590_I2.4261.00
206_Y211_F2.4251.00
78_S82_L2.3961.00
345_A510_V2.3641.00
609_T612_K2.3411.00
606_S610_F2.3311.00
131_V134_V2.3261.00
605_Y611_L2.3081.00
508_P512_I2.3061.00
516_I530_K2.2391.00
316_V544_V2.2151.00
207_K211_F2.2071.00
164_S167_Y2.2001.00
409_R417_K2.1901.00
210_D216_Y2.1901.00
484_E587_S2.1491.00
455_L459_E2.1331.00
273_V292_L2.1221.00
606_S609_T2.1001.00
243_A515_T2.0971.00
555_S558_Q2.0861.00
236_H535_M2.0681.00
63_K130_D2.0651.00
195_N228_G2.0451.00
568_V589_R2.0401.00
489_F510_V2.0321.00
684_V698_T2.0171.00
213_D216_Y1.9931.00
187_I241_V1.9871.00
604_S608_G1.9861.00
589_R592_N1.9851.00
257_L285_A1.9541.00
419_D423_K1.9541.00
173_A594_I1.9511.00
414_F444_P1.9231.00
122_I134_V1.9111.00
505_I540_I1.9001.00
454_S457_D1.9001.00
414_F417_K1.8971.00
222_P225_D1.8931.00
414_F431_V1.8901.00
199_L515_T1.8891.00
408_K462_V1.8761.00
182_G255_T1.8741.00
543_A563_I1.8721.00
417_K433_N1.8671.00
611_L614_N1.8561.00
347_Q510_V1.8441.00
404_V428_G1.8321.00
656_I660_Q1.8281.00
430_V451_I1.8241.00
86_R90_K1.8231.00
346_T506_S1.8161.00
319_T340_A1.8091.00
140_Y270_T1.8001.00
386_E408_K1.7891.00
406_V432_Y1.7841.00
624_T661_T1.7831.00
210_D221_T1.7831.00
382_V427_I1.7581.00
600_V696_V1.7131.00
277_V307_L1.7111.00
318_V541_A1.7041.00
554_W562_A1.7011.00
505_I563_I1.6941.00
259_Y283_D1.6801.00
604_S612_K1.6641.00
86_R89_A1.6611.00
418_A450_T1.6531.00
86_R105_E1.6441.00
605_Y609_T1.6421.00
210_D215_D1.6190.99
104_R275_A1.6110.99
193_E228_G1.6090.99
602_P606_S1.6070.99
274_I306_A1.6020.99
598_S635_Y1.5830.99
407_V429_M1.5820.99
624_T663_K1.5780.99
239_G515_T1.5720.99
688_E692_T1.5680.99
337_S340_A1.5560.99
188_I276_G1.5280.99
405_A427_I1.5260.99
625_I654_V1.5260.99
199_L239_G1.5250.99
261_V292_L1.5180.99
165_A168_I1.5130.99
620_N667_K1.5090.99
287_V316_V1.5070.99
218_P221_T1.5040.99
408_K432_Y1.4920.99
550_A594_I1.4860.99
605_Y610_F1.4820.99
580_H681_E1.4810.99
281_V309_W1.4800.99
124_K127_A1.4760.99
208_G211_F1.4520.99
239_G514_S1.4510.99
402_G427_I1.4390.99
457_D460_K1.4380.99
185_V254_A1.4380.99
540_I563_I1.4360.99
281_V310_A1.4340.99
199_L238_A1.4320.99
564_M585_A1.4310.99
537_S541_A1.4290.99
390_G393_K1.4190.99
123_P126_L1.4170.99
410_G433_N1.4130.98
277_V290_L1.4040.98
241_V542_G1.3950.98
507_A540_I1.3950.98
240_T539_H1.3900.98
664_A668_V1.3780.98
390_G394_D1.3780.98
604_S610_F1.3670.98
114_S271_E1.3630.98
547_I559_I1.3590.98
192_V258_A1.3570.98
407_V421_A1.3550.98
235_T517_P1.3470.98
142_T262_L1.3150.98
607_Y611_L1.3100.97
211_F221_T1.3100.97
184_K257_L1.3070.97
106_Y114_S1.3050.97
489_F531_Q1.3010.97
506_S536_A1.2990.97
604_S609_T1.2980.97
386_E432_Y1.2970.97
602_P612_K1.2970.97
341_I540_I1.2920.97
551_K554_W1.2850.97
86_R111_S1.2800.97
381_E473_T1.2770.97
148_K250_V1.2760.97
446_M450_T1.2640.97
279_R282_Q1.2620.97
414_F433_N1.2560.97
606_S614_N1.2560.97
230_A264_P1.2550.97
666_A670_V1.2490.97
285_A315_V1.2470.97
242_A256_L1.2460.97
108_Q278_E1.2450.97
289_N537_S1.2430.97
217_D220_E1.2420.97
206_Y221_T1.2390.96
422_K447_S1.2320.96
106_Y112_G1.2310.96
216_Y221_T1.2300.96
383_E403_K1.2300.96
78_S86_R1.2280.96
487_A531_Q1.2230.96
432_Y462_V1.2190.96
666_A684_V1.2130.96
560_K564_M1.2120.96
610_F613_E1.2090.96
492_R582_A1.2090.96
304_S337_S1.2080.96
240_T535_M1.2010.96
674_K678_G1.2000.96
63_K132_K1.1970.96
168_I172_D1.1940.96
416_D420_N1.1940.96
453_L457_D1.1920.96
598_S625_I1.1890.96
636_T653_R1.1880.96
505_I588_A1.1860.95
89_A93_A1.1850.95
346_T587_S1.1820.95
405_A426_A1.1780.95
104_R114_S1.1760.95
327_N330_T1.1740.95
606_S613_E1.1740.95
608_G614_N1.1690.95
547_I594_I1.1670.95
616_N619_K1.1620.95
405_A421_A1.1510.95
109_V278_E1.1510.95
406_V465_L1.1500.95
318_V537_S1.1460.95
486_V490_S1.1430.94
396_E399_D1.1380.94
167_Y172_D1.1380.94
210_D213_D1.1340.94
139_T269_T1.1310.94
363_A453_L1.1300.94
418_A429_M1.1290.94
418_A446_M1.1270.94
412_I420_N1.1270.94
109_V281_V1.1260.94
142_T268_G1.1240.94
250_V543_A1.1240.94
675_T678_G1.1220.94
308_D339_E1.1200.94
277_V288_M1.1190.94
57_T116_K1.1180.94
64_E85_A1.1180.94
206_Y255_T1.1170.94
625_I686_V1.1160.94
216_Y219_K1.1150.94
186_A280_A1.1130.94
211_F279_R1.1120.94
433_N437_G1.1120.94
604_S611_L1.1080.94
78_S81_K1.1060.93
190_T231_T1.1030.93
222_P226_P1.1010.93
409_R434_N1.1000.93
630_S659_H1.1000.93
273_V290_L1.0970.93
664_A686_V1.0970.93
664_A670_V1.0970.93
602_P611_L1.0950.93
61_E135_Y1.0940.93
326_P330_T1.0940.93
251_A545_A1.0870.93
206_Y209_Y1.0860.93
663_K666_A1.0850.93
637_L684_V1.0850.93
654_V664_A1.0820.93
279_R283_D1.0790.93
187_I238_A1.0780.93
206_Y216_Y1.0780.93
187_I237_V1.0770.93
654_V662_G1.0730.92
558_Q626_E1.0730.92
207_K257_L1.0720.92
410_G414_F1.0710.92
417_K431_V1.0710.92
295_S324_S1.0690.92
633_K688_E1.0680.92
236_H240_T1.0670.92
382_V385_V1.0650.92
418_A448_V1.0640.92
414_F434_N1.0640.92
183_I545_A1.0590.92
138_V270_T1.0540.92
513_V529_S1.0520.92
211_F216_Y1.0500.92
486_V582_A1.0490.92
85_A88_K1.0470.91
620_N665_T1.0410.91
82_L86_R1.0380.91
242_A254_A1.0370.91
422_K448_V1.0370.91
307_L340_A1.0360.91
387_A395_F1.0360.91
595_K692_T1.0350.91
61_E110_F1.0340.91
268_G272_N1.0340.91
87_T91_N1.0310.91
82_L85_A1.0240.90
557_E601_S1.0200.90
602_P605_Y1.0140.90
85_A90_K1.0120.90
648_T698_T1.0060.90
434_N437_G1.0050.90
184_K285_A1.0040.90
197_P526_G1.0030.90
180_G546_V0.9990.89
615_G619_K0.9970.89
688_E691_K0.9930.89
561_A565_N0.9910.89
681_E699_L0.9890.89
263_G272_N0.9850.89
612_K615_G0.9820.89
186_A288_M0.9800.88
465_L468_G0.9800.88
409_R452_K0.9760.88
459_E463_S0.9720.88
638_E685_I0.9700.88
400_L403_K0.9690.88
394_D420_N0.9680.88
625_I653_R0.9660.88
318_V540_I0.9650.88
409_R444_P0.9640.88
206_Y213_D0.9630.88
238_A256_L0.9630.88
635_Y688_E0.9560.87
318_V544_V0.9560.87
277_V310_A0.9560.87
61_E132_K0.9540.87
316_V556_V0.9520.87
432_Y458_G0.9520.87
137_N140_Y0.9470.87
236_H514_S0.9470.87
125_L131_V0.9460.87
413_A416_D0.9450.87
637_L664_A0.9420.86
395_F424_A0.9390.86
195_N518_T0.9380.86
287_V541_A0.9360.86
67_L71_K0.9360.86
414_F452_K0.9360.86
147_D250_V0.9350.86
605_Y613_E0.9330.86
168_I543_A0.9300.86
215_D218_P0.9300.86
301_W304_S0.9290.86
400_L405_A0.9270.86
213_D221_T0.9250.85
661_T664_A0.9220.85
235_T515_T0.9140.85
344_G486_V0.9100.84
62_L113_F0.9080.84
565_N623_F0.9060.84
405_A424_A0.9050.84
210_D214_N0.9040.84
326_P492_R0.9010.84
142_T190_T0.9000.84
95_K125_L0.8960.84
348_L512_I0.8950.83
260_R263_G0.8950.83
518_T526_G0.8920.83
430_V453_L0.8900.83
514_S535_M0.8890.83
268_G273_V0.8890.83
274_I277_V0.8890.83
638_E687_R0.8890.83
68_A71_K0.8890.83
417_K420_N0.8860.83
166_P172_D0.8860.83
70_A73_A0.8840.83
308_D337_S0.8820.83
608_G613_E0.8820.83
311_M316_V0.8810.82
166_P170_A0.8790.82
341_I560_K0.8730.82
501_I585_A0.8710.82
138_V301_W0.8690.82
603_G606_S0.8690.82
600_V694_A0.8680.82
548_K552_P0.8660.81
346_T486_V0.8640.81
143_D293_G0.8640.81
272_N275_A0.8640.81
389_I393_K0.8610.81
273_V276_G0.8610.81
598_S601_S0.8580.81
345_A531_Q0.8580.81
422_K446_M0.8570.81
240_T514_S0.8550.81
108_Q282_Q0.8530.80
169_G172_D0.8520.80
188_I288_M0.8510.80
602_P610_F0.8500.80
88_K91_N0.8500.80
686_V694_A0.8490.80
501_I699_L0.8480.80
117_L121_E0.8480.80
558_Q599_L0.8460.80
209_Y213_D0.8440.80
66_S111_S0.8430.80
192_V199_L0.8420.80
395_F407_V0.8410.79
563_I593_A0.8400.79
547_I593_A0.8380.79
210_D218_P0.8380.79
289_N318_V0.8370.79
190_T266_G0.8340.79
289_N541_A0.8330.79
682_G686_V0.8280.78
357_F360_Y0.8270.78
176_L595_K0.8260.78
118_P121_E0.8240.78
117_L125_L0.8240.78
632_R657_P0.8230.78
562_A566_T0.8230.78
600_V686_V0.8230.78
324_S491_S0.8230.78
602_P608_G0.8220.78
632_R658_A0.8210.78
419_D422_K0.8210.78
434_N455_L0.8200.78
579_P582_A0.8170.77
269_T272_N0.8130.77
83_K86_R0.8110.77
603_G608_G0.8110.77
207_K216_Y0.8110.77
551_K562_A0.8090.77
309_W315_V0.8080.77
186_A257_L0.8080.77
609_T613_E0.8080.77
85_A89_A0.8070.77
164_S168_I0.8070.77
507_A536_A0.8060.77
508_P539_H0.8060.77
415_V444_P0.8060.77
395_F405_A0.8020.76
320_S324_S0.8000.76
343_V505_I0.8000.76
121_E124_K0.8000.76
135_Y302_A0.8000.76
656_I662_G0.7990.76
490_S536_A0.7970.76
403_K427_I0.7970.76
277_V306_A0.7950.76
208_G216_Y0.7930.75
656_I686_V0.7930.75
578_Y583_Q0.7930.75
342_S504_D0.7920.75
395_F400_L0.7910.75
331_V336_T0.7910.75
78_S90_K0.7900.75
662_G665_T0.7900.75
600_V625_I0.7860.75
562_A596_A0.7860.75
363_A367_G0.7860.75
412_I416_D0.7850.75
360_Y663_K0.7850.75
185_V242_A0.7830.74
622_T665_T0.7820.74
217_D221_T0.7820.74
78_S85_A0.7800.74
393_K397_G0.7790.74
260_R264_P0.7750.74
433_N458_G0.7750.74
108_Q281_V0.7740.74
409_R425_G0.7720.73
468_G471_K0.7720.73
180_G251_A0.7720.73
141_K295_S0.7710.73
170_A174_W0.7700.73
165_A170_A0.7690.73
391_E411_S0.7680.73
566_T593_A0.7670.73
250_V539_H0.7660.73
504_D560_K0.7660.73
622_T663_K0.7650.73
309_W312_S0.7640.73
596_A694_A0.7610.72
418_A452_K0.7610.72
441_A452_K0.7610.72
101_K116_K0.7590.72
625_I660_Q0.7580.72
71_K74_G0.7580.72
256_L276_G0.7570.72
285_A339_E0.7550.72
237_V536_A0.7550.72
169_G589_R0.7550.72
69_E72_E0.7540.72
320_S451_I0.7540.72
173_A591_M0.7510.71
634_S653_R0.7500.71
240_T530_K0.7500.71
462_V466_K0.7490.71
414_F429_M0.7450.71
306_A310_A0.7450.71
208_G258_A0.7450.71
192_V256_L0.7450.71
512_I539_H0.7440.71
184_K255_T0.7440.71
376_A384_L0.7430.70
402_G502_K0.7420.70
495_V517_P0.7420.70
131_V648_T0.7420.70
627_N633_K0.7400.70
91_N95_K0.7400.70
465_L469_E0.7400.70
607_Y612_K0.7400.70
581_N699_L0.7380.70
650_G667_K0.7380.70
241_V254_A0.7380.70
569_T695_K0.7370.70
579_P681_E0.7360.70
124_K380_K0.7350.70
578_Y582_A0.7340.70
391_E412_I0.7330.69
685_I695_K0.7320.69
400_L424_A0.7310.69
146_K149_D0.7310.69
90_K105_E0.7300.69
183_I549_Q0.7290.69
103_N114_S0.7270.69
209_Y221_T0.7250.69
188_I277_V0.7250.69
206_Y212_V0.7250.69
610_F614_N0.7240.69
321_N342_S0.7240.69
598_S694_A0.7200.68
273_V530_K0.7200.68
501_I580_H0.7200.68
679_T701_I0.7200.68
597_D601_S0.7190.68
591_M595_K0.7180.68
187_I258_A0.7180.68
213_D219_K0.7170.68
432_Y453_L0.7170.68
407_V420_N0.7160.68
208_G213_D0.7160.68
319_T333_S0.7140.67
80_S83_K0.7140.67
285_A308_D0.7130.67
661_T666_A0.7110.67
625_I664_A0.7100.67
192_V238_A0.7100.67
355_V358_G0.7100.67
80_S89_A0.7060.67
409_R458_G0.7040.66
194_Y199_L0.7040.66
294_N297_N0.7030.66
226_P230_A0.7020.66
609_T614_N0.7020.66
270_T302_A0.7000.66
294_N332_G0.7000.66
287_V559_I0.6990.66
207_K255_T0.6990.66
497_D500_M0.6970.66
194_Y228_G0.6960.65
118_P122_I0.6950.65
637_L686_V0.6950.65
86_R107_E0.6950.65
57_T137_N0.6950.65
250_V542_G0.6920.65
61_E309_W0.6920.65
421_A425_G0.6920.65
414_F418_A0.6920.65
213_D218_P0.6910.65
650_G665_T0.6900.65
216_Y220_E0.6870.64
288_M310_A0.6860.64
233_H236_H0.6850.64
169_G591_M0.6850.64
408_K459_E0.6850.64
259_Y280_A0.6830.64
599_L628_Q0.6830.64
140_Y268_G0.6830.64
394_D398_K0.6820.64
206_Y257_L0.6820.64
429_M450_T0.6820.64
351_N480_K0.6820.64
293_G333_S0.6800.64
361_S460_K0.6790.64
226_P229_E0.6780.63
213_D220_E0.6780.63
329_W496_M0.6780.63
68_A72_E0.6780.63
144_N350_L0.6770.63
193_E196_H0.6770.63
186_A557_E0.6770.63
371_E376_A0.6760.63
106_Y275_A0.6760.63
186_A305_T0.6750.63
682_G697_P0.6740.63
410_G416_D0.6730.63
262_L510_V0.6710.63
307_L319_T0.6710.63
405_A431_V0.6700.63
102_V105_E0.6700.63
597_D623_F0.6700.63
362_S370_K0.6660.62
88_K127_A0.6660.62
173_A176_L0.6650.62
395_F420_N0.6650.62
405_A414_F0.6640.62
512_I535_M0.6640.62
180_G252_P0.6630.62
54_K119_A0.6630.62
604_S607_Y0.6620.62
663_K669_K0.6620.62
394_D397_G0.6600.61
434_N454_S0.6600.61
502_K560_K0.6590.61
447_S536_A0.6590.61
312_S668_V0.6570.61
388_G406_V0.6560.61
237_V320_S0.6540.61
231_T344_G0.6520.60
65_K68_A0.6510.60
197_P200_K0.6500.60
346_T570_L0.6490.60
273_V294_N0.6480.60
554_W558_Q0.6480.60
174_W179_T0.6470.60
164_S539_H0.6470.60
211_F214_N0.6460.60
341_I564_M0.6460.60
321_N331_V0.6450.60
198_D247_I0.6440.59
504_D564_M0.6430.59
359_S365_V0.6430.59
198_D245_G0.6420.59
168_I250_V0.6410.59
194_Y210_D0.6390.59
382_V387_A0.6390.59
284_G315_V0.6380.59
67_L72_E0.6370.59
637_L666_A0.6360.59
377_L382_V0.6360.59
459_E462_V0.6350.58
165_A172_D0.6350.58
603_G612_K0.6340.58
122_I126_L0.6340.58
84_T91_N0.6340.58
209_Y214_N0.6330.58
406_V461_L0.6320.58
280_A288_M0.6310.58
140_Y273_V0.6300.58
598_S692_T0.6300.58
190_T293_G0.6290.58
290_L307_L0.6290.58
107_E111_S0.6280.58
323_N534_S0.6280.58
446_M452_K0.6270.57
403_K433_N0.6270.57
418_A422_K0.6260.57
92_K128_V0.6260.57
342_S560_K0.6250.57
360_Y363_A0.6240.57
535_M538_P0.6240.57
347_Q404_V0.6230.57
581_N681_E0.6220.57
66_S72_E0.6220.57
68_A74_G0.6220.57
565_N598_S0.6210.57
460_K464_A0.6210.57
319_T336_T0.6210.57
201_K204_G0.6200.57
207_K213_D0.6200.57
407_V431_V0.6190.56
85_A94_I0.6190.56
188_I273_V0.6180.56
383_E386_E0.6180.56
336_T497_D0.6170.56
379_N382_V0.6160.56
168_I171_N0.6160.56
237_V240_T0.6160.56
87_T90_K0.6150.56
288_M292_L0.6140.56
358_G365_V0.6130.56
81_K84_T0.6120.56
212_V216_Y0.6120.56
293_G332_G0.6110.56
238_A545_A0.6110.56
618_T669_K0.6110.56
568_V587_S0.6100.55
439_I442_N0.6100.55
492_R579_P0.6100.55
400_L420_N0.6100.55
385_V512_I0.6100.55
508_P566_T0.6090.55
63_K66_S0.6090.55
428_G470_T0.6080.55
654_V686_V0.6080.55
56_T119_A0.6070.55
406_V472_T0.6070.55
229_E243_A0.6060.55
174_W546_V0.6060.55
146_K349_P0.6040.55
346_T510_V0.6040.55
518_T524_P0.6040.55
80_S86_R0.6030.55
417_K424_A0.6030.55
686_V696_V0.6020.54
590_I593_A0.6020.54
355_V451_I0.6010.54
320_S488_D0.6000.54
429_M448_V0.6000.54
390_G395_F0.6000.54
569_T683_T0.6000.54
657_P662_G0.5980.54
174_W178_Y0.5980.54
623_F686_V0.5980.54
398_K401_T0.5980.54
581_N679_T0.5980.54
167_Y174_W0.5970.54
64_E81_K0.5960.54
183_I548_K0.5960.54
383_E387_A0.5960.54
539_H543_A0.5950.54
593_A627_N0.5950.54
355_V363_A0.5950.54
103_N121_E0.5950.54
262_L292_L0.5940.53
580_H583_Q0.5930.53
610_F615_G0.5920.53
211_F215_D0.5920.53
456_E478_V0.5910.53
633_K692_T0.5900.53
110_F135_Y0.5900.53
259_Y279_R0.5890.53
82_L93_A0.5870.53
237_V289_N0.5870.53
512_I635_Y0.5860.52
392_A398_K0.5860.52
122_I131_V0.5850.52
278_E282_Q0.5850.52
289_N437_G0.5840.52
232_D243_A0.5840.52
194_Y200_K0.5840.52
392_A416_D0.5830.52
62_L180_G0.5830.52
199_L243_A0.5830.52
683_T695_K0.5820.52
79_K82_L0.5820.52
178_Y549_Q0.5820.52
603_G610_F0.5810.52
418_A444_P0.5810.52
268_G345_A0.5810.52
210_D219_K0.5800.52
649_S652_S0.5800.52
605_Y614_N0.5800.52
431_V444_P0.5800.52
81_K85_A0.5790.52
138_V185_V0.5790.52
311_M317_A0.5780.51
383_E461_L0.5770.51
542_G547_I0.5760.51
453_L573_S0.5760.51
325_G491_S0.5750.51
281_V306_A0.5750.51
287_V343_V0.5750.51
81_K86_R0.5750.51
621_E699_L0.5750.51
124_K658_A0.5750.51
304_S307_L0.5730.51
232_D516_I0.5730.51
65_K74_G0.5720.51
308_D338_R0.5720.51
596_A692_T0.5700.50
408_K455_L0.5690.50
209_Y279_R0.5690.50
663_K667_K0.5690.50
173_A546_V0.5690.50
433_N452_K0.5680.50
380_K647_S0.5680.50
649_S669_K0.5670.50
310_A345_A0.5670.50
184_K203_F0.5660.50
178_Y594_I0.5660.50
651_T656_I0.5650.50
381_E385_V0.5640.50
593_A688_E0.5630.50
495_V498_T0.5630.50
333_S342_S0.5620.50
207_K221_T0.5610.49
463_S467_A0.5600.49
378_N381_E0.5600.49
381_E471_K0.5590.49
431_V441_A0.5590.49
385_V388_G0.5590.49
66_S74_G0.5590.49
421_A429_M0.5590.49
389_I433_N0.5580.49
511_N531_Q0.5580.49
353_Y478_V0.5570.49
236_H530_K0.5570.49
530_K535_M0.5570.49
188_I257_L0.5570.49
193_E518_T0.5540.49
184_K341_I0.5530.48
92_K547_I0.5520.48
130_D134_V0.5520.48
80_S84_T0.5520.48
368_Y649_S0.5520.48
81_K89_A0.5510.48
121_E684_V0.5510.48
572_D582_A0.5510.48
268_G294_N0.5500.48
176_L591_M0.5500.48
173_A547_I0.5500.48
420_N424_A0.5500.48
87_T105_E0.5490.48
62_L89_A0.5490.48
603_G607_Y0.5480.48
281_V284_G0.5460.48
90_K102_V0.5460.48
208_G292_L0.5460.48
275_A279_R0.5450.47
307_L313_E0.5450.47
174_W406_V0.5440.47
477_T588_A0.5420.47
192_V203_F0.5410.47
548_K555_S0.5410.47
639_Y678_G0.5400.47
358_G464_A0.5400.47
287_V309_W0.5400.47
474_F547_I0.5390.47
525_Y528_G0.5390.47
58_V115_M0.5390.47
636_T687_R0.5380.47
656_I661_T0.5370.46
321_N344_G0.5370.46
185_V545_A0.5370.46
86_R93_A0.5360.46
106_Y110_F0.5360.46
360_Y368_Y0.5360.46
190_T235_T0.5350.46
242_A258_A0.5350.46
173_A652_S0.5350.46
655_V658_A0.5340.46
341_I556_V0.5330.46
498_T610_F0.5330.46
233_H323_N0.5330.46
355_V365_V0.5330.46
397_G400_L0.5330.46
72_E81_K0.5330.46
565_N600_V0.5320.46
640_S683_T0.5320.46
298_N304_S0.5310.46
198_D515_T0.5300.46
414_F426_A0.5290.45
67_L78_S0.5290.45
338_R555_S0.5290.45
97_V102_V0.5290.45
629_S633_K0.5290.45
631_I652_S0.5280.45
654_V684_V0.5270.45
400_L427_I0.5260.45
393_K420_N0.5260.45
464_A467_A0.5260.45
67_L82_L0.5260.45
507_A512_I0.5260.45
516_I536_A0.5250.45
231_T269_T0.5250.45
682_G698_T0.5250.45
431_V452_K0.5240.45
440_E488_D0.5240.45
59_I110_F0.5230.45
409_R437_G0.5220.45
54_K126_L0.5220.45
208_G212_V0.5210.44
410_G450_T0.5210.44
314_G556_V0.5200.44
186_A259_Y0.5200.44
664_A667_K0.5200.44
339_E623_F0.5200.44
648_T668_V0.5190.44
494_P699_L0.5180.44
510_V531_Q0.5180.44
307_L337_S0.5180.44
57_T103_N0.5170.44
384_L453_L0.5170.44
210_D220_E0.5170.44
381_E384_L0.5170.44
393_K396_E0.5170.44
634_S663_K0.5160.44
363_A370_K0.5160.44
102_V217_D0.5160.44
316_V548_K0.5160.44
228_G232_D0.5150.44
391_E416_D0.5150.44
276_G578_Y0.5150.44
109_V309_W0.5150.44
560_K565_N0.5140.44
494_P513_V0.5140.44
168_I539_H0.5140.44
386_E462_V0.5130.44
414_F439_I0.5130.44
546_V590_I0.5130.44
547_I590_I0.5120.43
62_L86_R0.5120.43
390_G407_V0.5110.43
596_A686_V0.5110.43
639_Y648_T0.5100.43
235_T264_P0.5100.43
168_I588_A0.5100.43
324_S537_S0.5100.43
465_L471_K0.5100.43
250_V627_N0.5100.43
81_K91_N0.5090.43
184_K201_K0.5090.43
394_D412_I0.5090.43
409_R431_V0.5090.43
641_F644_S0.5080.43
611_L699_L0.5070.43
412_I417_K0.5070.43
216_Y263_G0.5070.43
126_L134_V0.5070.43
389_I410_G0.5060.43
88_K93_A0.5050.43
417_K458_G0.5050.43
53_S56_T0.5050.43
404_V427_I0.5050.43
414_F437_G0.5040.42
251_A550_A0.5040.42
444_P450_T0.5040.42
349_P483_G0.5040.42
287_V461_L0.5030.42
561_A599_L0.5030.42
410_G431_V0.5030.42
198_D257_L0.5030.42
537_S540_I0.5030.42
198_D561_A0.5030.42
110_F281_V0.5030.42
618_T655_V0.5020.42
83_K87_T0.5020.42
607_Y699_L0.5020.42
65_K69_E0.5010.42
307_L317_A0.5010.42
315_V344_G0.5000.42
646_I668_V0.5000.42
413_A417_K0.5000.42
292_L304_S0.5000.42
213_D292_L0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1xf1A 2 0.763 100 0.415 Contact Map
3i6sA 2 0.6551 100 0.489 Contact Map
3vtaA 1 0.6402 100 0.5 Contact Map
3afgA 1 0.5856 100 0.615 Contact Map
3whiA 2 0.4392 100 0.645 Contact Map
4i0wB 1 0.5186 100 0.654 Contact Map
2p4eP 2 0.6476 100 0.657 Contact Map
3wiuA 2 0.4442 100 0.661 Contact Map
3t41A 1 0.4529 100 0.662 Contact Map
1y9zA 1 0.4727 100 0.666 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0166 seconds.