GREMLIN Database
CHEA - Chemotaxis protein CheA
UniProt: P29072 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 672 (649)
Sequences: 2443 (1856)
Seq/√Len: 72.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
453_L458_I8.0411.00
525_A528_Q7.9301.00
421_L427_E7.8451.00
378_K427_E7.6741.00
419_T451_A6.8091.00
423_K527_G6.5101.00
380_E428_S6.2811.00
31_D34_D5.3901.00
91_E119_K4.9221.00
447_E531_L4.4711.00
378_K428_S4.3891.00
384_I432_V4.3591.00
225_A229_E4.2821.00
459_L468_I4.2731.00
455_R478_D4.1841.00
382_S430_K4.1541.00
461_K464_E4.1121.00
371_L499_I3.9531.00
454_N526_E3.8661.00
416_A419_T3.7251.00
580_E593_Y3.7031.00
455_R481_I3.6961.00
564_E585_R3.5691.00
224_S227_D3.5131.00
419_T422_Q3.4381.00
460_E464_E3.3441.00
459_L481_I3.3371.00
549_K628_S3.3141.00
591_V612_I3.2761.00
410_I431_V3.1801.00
457_K494_D3.1211.00
419_T423_K3.0771.00
453_L482_Y3.0291.00
379_I410_I2.8941.00
486_F520_V2.8741.00
38_V74_I2.8721.00
477_E480_Q2.8601.00
587_H621_P2.8081.00
545_V556_A2.7151.00
73_A78_D2.6981.00
456_K460_E2.5561.00
455_R459_L2.5101.00
459_L463_L2.4341.00
478_D481_I2.4281.00
612_I623_A2.4221.00
455_R526_E2.4051.00
66_L121_D2.3441.00
380_E430_K2.3301.00
482_Y524_S2.2811.00
374_E498_D2.2191.00
467_V487_A2.1981.00
379_I414_I2.1361.00
70_V120_L2.1281.00
432_V447_E2.1181.00
598_F665_I2.1021.00
436_Y445_E2.0781.00
455_R482_Y2.0601.00
467_V484_L2.0531.00
470_E474_E2.0511.00
485_I506_L2.0441.00
67_L92_A2.0021.00
29_E369_R2.0001.00
45_A64_T1.9941.00
406_I431_V1.9931.00
414_I429_G1.9531.00
17_H44_A1.9171.00
468_I476_L1.9021.00
361_F433_L1.8871.00
223_Q227_D1.8841.00
219_F228_I1.8801.00
555_F600_I1.8751.00
486_F522_V1.8641.00
42_F75_R1.8611.00
15_K104_I1.8541.00
479_N523_K1.8451.00
589_V614_V1.8141.00
35_L77_G1.8121.00
583_D586_G1.8071.00
451_A457_K1.7691.00
118_A122_V1.7431.00
368_I410_I1.7351.00
593_Y625_V1.7341.00
441_H535_Q1.7331.00
114_S118_A1.6881.00
417_P427_E1.6731.00
168_I243_V1.6591.00
557_I613_I1.6551.00
416_A451_A1.6511.00
476_L484_L1.6461.00
456_K459_L1.6451.00
610_L625_V1.6451.00
584_F614_V1.6371.00
73_A79_M1.6280.99
358_E386_A1.6050.99
363_R399_G1.5990.99
409_S532_F1.5910.99
453_L485_I1.5740.99
260_Q264_P1.5630.99
368_I406_I1.5510.99
506_L532_F1.5480.99
479_N521_S1.5410.99
165_R220_L1.5400.99
85_W123_N1.5300.99
82_T85_W1.5280.99
295_I302_L1.5260.99
461_K465_R1.5240.99
53_A61_A1.5170.99
190_L194_G1.5170.99
171_S214_D1.5030.99
67_L96_L1.4950.99
400_D508_V1.4860.99
451_A454_N1.4800.99
523_K533_S1.4740.99
464_E494_D1.4730.99
569_D572_D1.4720.99
87_D373_K1.4700.99
549_K552_E1.4670.99
316_R556_A1.4660.99
232_I235_V1.4650.99
19_Q97_E1.4630.99
458_I481_I1.4630.99
414_I451_A1.4530.99
35_L39_H1.4390.99
206_L212_G1.4370.99
164_K245_Q1.4310.99
169_K216_Q1.4290.99
74_I85_W1.4250.99
434_K445_E1.4170.99
226_E229_E1.4100.99
122_V126_H1.4060.98
29_E32_P1.3900.98
375_L410_I1.3890.98
384_I434_K1.3880.98
350_L541_S1.3850.98
418_E427_E1.3800.98
445_E533_S1.3760.98
269_P273_E1.3740.98
459_L476_L1.3710.98
360_V365_P1.3670.98
556_A634_E1.3670.98
457_K460_E1.3620.98
22_N90_F1.3590.98
262_D265_A1.3570.98
423_K451_A1.3530.98
74_I81_V1.3520.98
468_I481_I1.3490.98
562_I613_I1.3420.98
522_V532_F1.3410.98
468_I484_L1.3270.98
15_K101_Q1.3170.98
544_S634_E1.3060.98
547_L656_L1.3050.98
227_D231_L1.3040.98
582_I612_I1.3020.97
455_R524_S1.2950.97
257_E260_Q1.2870.97
226_E230_Q1.2840.97
482_Y526_E1.2810.97
556_A662_A1.2710.97
167_E216_Q1.2700.97
59_D109_G1.2670.97
113_I116_V1.2640.97
149_E155_I1.2590.97
178_L182_R1.2530.97
307_N638_K1.2530.97
565_T629_F1.2500.97
263_S278_P1.2470.97
378_K421_L1.2410.97
379_I431_V1.2390.97
615_V667_C1.2380.97
227_D230_Q1.2380.97
72_D76_N1.2360.97
166_Y221_T1.2340.97
262_D267_A1.2290.96
202_S205_V1.2250.96
418_E421_L1.2240.96
155_I158_A1.2140.96
434_K447_E1.2110.96
46_H49_K1.2110.96
232_I241_V1.2070.96
349_I352_M1.2060.96
364_F433_L1.2050.96
43_R46_H1.2010.96
482_Y522_V1.2000.96
262_D266_A1.1950.96
148_D152_R1.1940.96
398_I512_K1.1930.96
461_K494_D1.1910.96
563_I616_K1.1830.96
355_V395_I1.1830.96
417_P421_L1.1780.95
318_R334_T1.1710.95
364_F371_L1.1680.95
595_K602_D1.1670.95
493_A496_I1.1660.95
182_R185_M1.1650.95
520_V532_F1.1630.95
58_T62_H1.1480.95
381_L406_I1.1440.95
257_E262_D1.1410.95
148_D151_E1.1390.95
556_A635_V1.1390.95
551_E600_I1.1360.94
463_L468_I1.1360.94
457_K464_E1.1330.94
263_S267_A1.1290.94
258_S263_S1.1280.94
17_H20_T1.1200.94
394_V398_I1.1170.94
367_M371_L1.1130.94
411_D500_S1.1090.94
258_S262_D1.1080.94
545_V635_V1.1070.94
516_L536_L1.1030.94
10_F52_S1.1010.94
33_T80_E1.1000.93
182_R186_V1.0970.93
52_S61_A1.0950.93
18_L96_L1.0910.93
239_E243_V1.0910.93
262_D273_E1.0890.93
270_A275_Q1.0860.93
447_E528_Q1.0860.93
147_Y150_F1.0800.93
460_E463_L1.0770.93
557_I624_F1.0700.93
463_L476_L1.0690.92
26_L29_E1.0680.92
319_L334_T1.0670.92
382_S432_V1.0660.92
261_E265_A1.0640.92
154_V160_E1.0610.92
179_K182_R1.0550.92
168_I172_L1.0540.92
237_E241_V1.0500.92
463_L470_E1.0480.92
134_E137_E1.0460.92
361_F564_E1.0450.92
43_R49_K1.0420.91
195_E220_L1.0400.91
113_I117_S1.0360.91
278_P281_N1.0360.91
438_S535_Q1.0330.91
45_A71_L1.0330.91
280_K283_E1.0310.91
118_A121_D1.0280.91
232_I238_I1.0280.91
257_E265_A1.0280.91
230_Q234_G1.0270.91
431_V530_S1.0270.91
178_L181_V1.0260.91
47_T51_M1.0230.91
546_L613_I1.0230.91
49_K68_E1.0220.91
6_Y54_T1.0220.91
17_H51_M1.0220.91
93_L97_E1.0210.91
364_F367_M1.0200.91
277_Q280_K1.0190.91
119_K122_V1.0180.91
54_T71_L1.0170.90
511_N520_V1.0170.90
67_L89_L1.0160.90
177_M183_V1.0150.90
213_T228_I1.0150.90
259_K263_S1.0150.90
177_M180_A1.0130.90
612_I625_V1.0090.90
166_Y225_A1.0050.90
40_D52_S1.0020.90
46_H65_H1.0020.90
22_N97_E1.0010.90
316_R634_E0.9970.90
465_R481_I0.9950.89
549_K630_I0.9940.89
521_S535_Q0.9930.89
315_D338_M0.9930.89
180_A183_V0.9930.89
152_R155_I0.9880.89
457_K465_R0.9870.89
418_E422_Q0.9860.89
308_L348_I0.9820.89
90_F406_I0.9810.89
316_R545_V0.9810.89
517_G637_L0.9800.89
46_H50_G0.9790.89
458_I485_I0.9760.89
43_R65_H0.9730.88
256_E262_D0.9710.88
95_H116_V0.9640.88
135_P268_V0.9610.88
207_E211_F0.9590.88
106_G110_K0.9540.87
79_M85_W0.9540.87
231_L234_G0.9500.87
302_L641_G0.9490.87
611_H629_F0.9470.87
638_K657_G0.9460.87
346_Q635_V0.9430.87
168_I217_V0.9420.87
580_E596_E0.9390.87
264_P270_A0.9380.87
264_P269_P0.9380.87
485_I661_V0.9370.86
550_L600_I0.9340.86
258_S266_A0.9340.86
21_C349_I0.9320.86
165_R245_Q0.9320.86
260_Q266_A0.9290.86
125_A128_E0.9290.86
228_I237_E0.9260.86
260_Q268_V0.9250.86
426_P430_K0.9240.86
454_N482_Y0.9230.86
555_F598_F0.9220.86
322_I331_L0.9210.86
498_D536_L0.9210.86
60_L100_V0.9190.85
545_V634_E0.9180.85
261_E266_A0.9170.85
266_A269_P0.9150.85
94_D366_R0.9140.85
595_K605_K0.9120.85
135_P140_S0.9110.85
147_Y151_E0.9090.85
57_Y61_A0.9090.85
61_A64_T0.9080.85
366_R370_Q0.9070.85
255_P267_A0.9070.85
352_M355_V0.9020.84
156_Q159_E0.9010.84
523_K531_L0.9010.84
179_K183_V0.8990.84
554_T630_I0.8990.84
221_T243_V0.8990.84
20_T44_A0.8970.84
378_K417_P0.8940.84
39_H508_V0.8920.84
24_K37_L0.8920.84
555_F592_V0.8910.84
205_V210_D0.8900.84
268_V273_E0.8870.83
130_A269_P0.8850.83
203_A206_L0.8850.83
59_D103_I0.8840.83
266_A271_K0.8830.83
57_Y64_T0.8830.83
269_P275_Q0.8820.83
485_I522_V0.8820.83
272_Q283_E0.8810.83
45_A54_T0.8800.83
201_P206_L0.8800.83
480_Q483_E0.8800.83
47_T643_Y0.8800.83
598_F649_A0.8790.83
6_Y51_M0.8780.83
189_K192_E0.8770.83
71_L445_E0.8750.82
51_M55_M0.8750.82
24_K40_D0.8740.82
465_R490_F0.8740.82
71_L661_V0.8720.82
547_L556_A0.8710.82
368_I372_Q0.8700.82
494_D531_L0.8700.82
162_G165_R0.8690.82
6_Y55_M0.8680.82
261_E275_Q0.8670.82
155_I159_E0.8670.82
121_D125_A0.8630.82
460_E470_E0.8630.82
354_M538_L0.8620.82
258_S264_P0.8620.82
11_I103_I0.8610.81
394_V399_G0.8600.81
14_S48_L0.8590.81
39_H615_V0.8580.81
493_A497_S0.8580.81
592_V670_L0.8580.81
653_A663_L0.8570.81
439_G490_F0.8560.81
478_D525_A0.8560.81
131_A264_P0.8560.81
71_L85_W0.8550.81
88_I123_N0.8540.81
346_Q506_L0.8540.81
540_L636_V0.8540.81
63_L67_L0.8530.81
38_V651_S0.8480.80
106_G109_G0.8470.80
73_A124_G0.8450.80
47_T318_R0.8430.80
267_A270_A0.8390.80
101_Q105_D0.8370.80
43_R50_G0.8360.79
167_E244_I0.8340.79
314_I633_Q0.8330.79
543_I641_G0.8320.79
172_L176_C0.8310.79
168_I219_F0.8310.79
281_N284_Q0.8300.79
163_F222_H0.8300.79
208_T213_T0.8300.79
159_E162_G0.8290.79
315_D318_R0.8280.79
115_E119_K0.8280.79
263_S275_Q0.8270.79
118_A133_A0.8270.79
313_V346_Q0.8270.79
224_S256_E0.8260.79
272_Q276_K0.8250.79
181_V185_M0.8250.79
28_L32_P0.8240.79
166_Y172_L0.8230.78
318_R403_V0.8220.78
228_I243_V0.8220.78
51_M632_Q0.8210.78
150_F154_V0.8200.78
258_S265_A0.8180.78
165_R170_I0.8170.78
236_S239_E0.8170.78
264_P268_V0.8160.78
172_L177_M0.8150.78
51_M54_T0.8140.78
169_K214_D0.8140.78
168_I190_L0.8130.78
228_I233_N0.8130.78
390_L542_I0.8120.77
185_M189_K0.8080.77
229_E236_S0.8070.77
46_H68_E0.8060.77
219_F234_G0.8050.77
132_S136_A0.8050.77
55_M183_V0.8040.77
476_L481_I0.8030.77
361_F585_R0.8020.77
49_K65_H0.8020.77
354_M375_L0.8020.77
215_F221_T0.8010.77
301_R651_S0.8000.76
276_K283_E0.8000.76
317_G392_R0.7980.76
262_D278_P0.7960.76
276_K281_N0.7960.76
221_T228_I0.7960.76
261_E267_A0.7950.76
542_I636_V0.7950.76
299_I517_G0.7940.76
277_Q281_N0.7940.76
5_Q12_D0.7940.76
318_R634_E0.7930.76
219_F242_E0.7920.76
262_D272_Q0.7920.76
158_A162_G0.7920.76
256_E276_K0.7910.76
263_S268_V0.7900.76
193_V219_F0.7890.75
63_L95_H0.7880.75
235_V238_I0.7880.75
444_I573_I0.7870.75
135_P138_A0.7850.75
266_A283_E0.7840.75
94_D370_Q0.7830.75
525_A531_L0.7820.75
17_H47_T0.7820.75
388_T439_G0.7800.75
493_A499_I0.7800.75
178_L183_V0.7690.74
170_I176_C0.7690.74
75_R508_V0.7690.74
295_I392_R0.7680.73
459_L623_A0.7660.73
259_K278_P0.7650.73
321_Q658_D0.7640.73
520_V639_S0.7630.73
263_S270_A0.7630.73
29_E387_E0.7620.73
471_K474_E0.7620.73
221_T395_I0.7620.73
26_L90_F0.7610.73
565_T634_E0.7610.73
169_K242_E0.7600.73
261_E270_A0.7600.73
437_H540_L0.7600.73
199_T204_E0.7590.73
168_I232_I0.7590.73
354_M388_T0.7560.72
613_I626_V0.7550.72
512_K520_V0.7550.72
64_T96_L0.7510.72
178_L191_N0.7510.72
323_A331_L0.7500.72
256_E263_S0.7480.71
388_T540_L0.7480.71
171_S240_H0.7460.71
553_E664_I0.7450.71
64_T405_L0.7440.71
193_V231_L0.7410.71
133_A137_E0.7410.71
593_Y596_E0.7390.71
546_L562_I0.7390.71
266_A272_Q0.7380.70
464_E495_Q0.7370.70
269_P272_Q0.7360.70
52_S57_Y0.7360.70
133_A573_I0.7350.70
21_C71_L0.7350.70
136_A139_Q0.7340.70
257_E269_P0.7340.70
440_N512_K0.7340.70
301_R512_K0.7330.70
546_L616_K0.7320.70
81_V85_W0.7310.70
266_A422_Q0.7300.70
266_A277_Q0.7300.70
478_D482_Y0.7300.70
354_M437_H0.7290.70
256_E271_K0.7290.70
463_L471_K0.7270.69
259_K264_P0.7260.69
541_S637_L0.7230.69
553_E600_I0.7220.69
581_V657_G0.7220.69
69_N72_D0.7200.69
284_Q287_H0.7200.69
322_I557_I0.7200.69
259_K265_A0.7200.69
42_F65_H0.7190.68
256_E282_D0.7170.68
54_T61_A0.7160.68
456_K478_D0.7150.68
257_E271_K0.7150.68
147_Y157_E0.7140.68
234_G243_V0.7140.68
255_P266_A0.7140.68
636_V664_I0.7130.68
7_L57_Y0.7120.68
276_K280_K0.7120.68
43_R47_T0.7120.68
510_K514_E0.7120.68
234_G241_V0.7110.68
221_T224_S0.7110.68
128_E284_Q0.7090.67
294_T345_L0.7080.67
346_Q350_L0.7070.67
258_S271_K0.7070.67
279_A601_E0.7070.67
559_I634_E0.7070.67
45_A67_L0.7060.67
376_N418_E0.7050.67
559_I632_Q0.7030.67
175_N178_L0.7020.67
154_V158_A0.7020.67
445_E531_L0.7020.67
132_S257_E0.7010.67
261_E264_P0.7000.66
208_T211_F0.7000.66
208_T232_I0.6990.66
70_V479_N0.6990.66
134_E272_Q0.6980.66
228_I234_G0.6970.66
154_V159_E0.6970.66
257_E261_E0.6960.66
267_A272_Q0.6950.66
437_H651_S0.6940.66
90_F661_V0.6940.66
168_I228_I0.6910.65
405_L653_A0.6890.65
322_I334_T0.6880.65
440_N540_L0.6870.65
43_R68_E0.6860.65
368_I431_V0.6850.65
270_A274_K0.6850.65
271_K276_K0.6820.64
232_I237_E0.6820.64
162_G166_Y0.6810.64
97_E101_Q0.6800.64
437_H538_L0.6790.64
50_G65_H0.6790.64
346_Q565_T0.6770.64
458_I468_I0.6770.64
26_L38_V0.6770.64
22_N512_K0.6770.64
228_I231_L0.6760.64
265_A268_V0.6740.63
126_H129_S0.6740.63
454_N460_E0.6740.63
130_A270_A0.6730.63
272_Q279_A0.6730.63
344_D405_L0.6720.63
395_I540_L0.6720.63
338_M342_S0.6680.63
162_G168_I0.6680.63
14_S17_H0.6670.63
148_D157_E0.6670.63
433_L564_E0.6670.63
26_L370_Q0.6660.63
259_K270_A0.6650.62
595_K604_R0.6650.62
205_V255_P0.6650.62
137_E140_S0.6650.62
152_R156_Q0.6630.62
64_T390_L0.6620.62
321_Q325_E0.6620.62
258_S272_Q0.6610.62
44_A665_I0.6610.62
454_N478_D0.6600.62
51_M355_V0.6590.62
29_E370_Q0.6590.62
136_A140_S0.6590.62
559_I637_L0.6580.62
346_Q365_P0.6580.62
467_V566_A0.6580.62
180_A215_F0.6570.61
316_R339_T0.6570.61
229_E240_H0.6570.61
133_A264_P0.6550.61
354_M623_A0.6540.61
184_Y187_F0.6540.61
4_N347_S0.6540.61
546_L653_A0.6530.61
302_L318_R0.6530.61
188_E191_N0.6520.61
400_D541_S0.6510.61
354_M370_Q0.6510.61
222_H274_K0.6510.61
308_L414_I0.6500.61
309_F347_S0.6500.61
13_E42_F0.6490.61
308_L543_I0.6490.61
653_A661_V0.6490.61
263_S271_K0.6480.60
62_H414_I0.6480.60
147_Y155_I0.6480.60
183_V239_E0.6470.60
215_F234_G0.6460.60
265_A273_E0.6460.60
183_V238_I0.6460.60
309_F541_S0.6450.60
554_T660_E0.6440.60
267_A275_Q0.6430.60
268_V271_K0.6430.60
219_F243_V0.6430.60
14_S100_V0.6420.60
274_K278_P0.6410.60
34_D39_H0.6410.60
335_V632_Q0.6410.60
498_D513_L0.6400.59
160_E163_F0.6390.59
375_L499_I0.6390.59
215_F219_F0.6390.59
207_E210_D0.6380.59
234_G238_I0.6380.59
343_G634_E0.6370.59
411_D507_D0.6360.59
595_K610_L0.6350.59
405_L532_F0.6350.59
444_I661_V0.6340.59
432_V446_V0.6340.59
267_A277_Q0.6330.59
409_S619_D0.6330.59
172_L180_A0.6320.59
436_Y443_F0.6320.59
65_H68_E0.6320.59
138_A245_Q0.6310.58
455_R458_I0.6290.58
269_P276_K0.6290.58
275_Q278_P0.6270.58
221_T231_L0.6270.58
440_N565_T0.6250.58
440_N545_V0.6250.58
221_T234_G0.6230.57
316_R544_S0.6230.57
57_Y103_I0.6220.57
131_A134_E0.6210.57
262_D284_Q0.6210.57
82_T242_E0.6210.57
99_M103_I0.6200.57
186_V190_L0.6190.57
140_S258_S0.6190.57
138_A274_K0.6190.57
312_L345_L0.6190.57
261_E272_Q0.6180.57
22_N51_M0.6170.57
55_M182_R0.6170.57
278_P283_E0.6160.57
225_A245_Q0.6160.57
544_S556_A0.6160.57
268_V427_E0.6150.56
190_L219_F0.6140.56
320_E339_T0.6130.56
332_T592_V0.6130.56
256_E280_K0.6120.56
255_P272_Q0.6120.56
534_I540_L0.6120.56
314_I654_T0.6120.56
273_E276_K0.6110.56
346_Q638_K0.6110.56
129_S275_Q0.6100.56
400_D512_K0.6100.56
641_G661_V0.6090.56
262_D271_K0.6090.56
53_A508_V0.6080.56
92_A589_V0.6080.56
431_V589_V0.6070.55
372_Q566_A0.6070.55
390_L562_I0.6060.55
157_E162_G0.6050.55
201_P207_E0.6050.55
157_E273_E0.6050.55
115_E271_K0.6030.55
259_K273_E0.6030.55
80_E125_A0.6010.55
396_D512_K0.6010.55
179_K237_E0.6010.55
172_L232_I0.6000.55
150_F153_T0.5990.55
355_V651_S0.5990.55
131_A156_Q0.5970.54
481_I576_T0.5970.54
582_I623_A0.5970.54
189_K194_G0.5960.54
318_R344_D0.5950.54
261_E281_N0.5940.54
228_I241_V0.5940.54
54_T346_Q0.5930.54
130_A136_A0.5930.54
355_V633_Q0.5920.54
398_I548_I0.5920.54
423_K426_P0.5920.54
427_E430_K0.5910.54
265_A269_P0.5910.54
52_S629_F0.5910.54
409_S530_S0.5900.53
9_V17_H0.5900.53
233_N236_S0.5900.53
483_E510_K0.5900.53
166_Y228_I0.5900.53
48_L512_K0.5890.53
570_R608_E0.5890.53
301_R351_N0.5880.53
208_T215_F0.5880.53
666_D669_A0.5870.53
122_V127_A0.5860.53
457_K461_K0.5860.53
309_F345_L0.5840.53
229_E232_I0.5840.53
83_S552_E0.5830.53
55_M306_M0.5830.53
274_K287_H0.5830.53
256_E287_H0.5820.52
157_E272_Q0.5810.52
262_D270_A0.5810.52
593_Y610_L0.5810.52
388_T534_I0.5810.52
165_R276_K0.5800.52
615_V624_F0.5800.52
264_P273_E0.5800.52
217_V221_T0.5780.52
206_L211_F0.5780.52
75_R504_V0.5780.52
19_Q23_E0.5770.52
545_V636_V0.5760.52
301_R343_G0.5760.52
649_A666_D0.5750.52
50_G68_E0.5750.52
274_K277_Q0.5740.51
263_S272_Q0.5740.51
262_D277_Q0.5740.51
235_V496_I0.5730.51
454_N494_D0.5730.51
414_I417_P0.5720.51
197_A220_L0.5720.51
263_S269_P0.5710.51
274_K280_K0.5710.51
363_R585_R0.5710.51
151_E155_I0.5710.51
27_L30_K0.5710.51
543_I635_V0.5700.51
317_G352_M0.5700.51
319_L335_V0.5700.51
54_T64_T0.5690.51
259_K456_K0.5690.51
268_V272_Q0.5690.51
361_F364_F0.5690.51
259_K262_D0.5680.51
410_I417_P0.5680.51
270_A273_E0.5680.51
17_H93_L0.5680.51
150_F159_E0.5680.51
36_Q39_H0.5680.51
103_I431_V0.5670.51
231_L239_E0.5660.50
227_D232_I0.5660.50
326_L331_L0.5650.50
170_I243_V0.5650.50
639_S644_L0.5640.50
479_N483_E0.5630.50
273_E282_D0.5630.50
400_D542_I0.5620.50
351_N545_V0.5610.50
358_E367_M0.5610.50
559_I640_L0.5600.50
514_E623_A0.5600.50
313_V598_F0.5590.50
245_Q274_K0.5580.49
70_V431_V0.5580.49
65_H94_D0.5580.49
131_A160_E0.5570.49
430_K457_K0.5570.49
259_K272_Q0.5570.49
563_I661_V0.5570.49
265_A270_A0.5560.49
76_N371_L0.5560.49
350_L611_H0.5560.49
148_D155_I0.5560.49
170_I174_E0.5550.49
13_E65_H0.5550.49
22_N644_L0.5550.49
542_I666_D0.5540.49
461_K467_V0.5530.49
274_K279_A0.5530.49
442_V485_I0.5530.49
47_T347_S0.5530.49
256_E259_K0.5530.49
317_G633_Q0.5520.49
178_L184_Y0.5520.49
546_L565_T0.5520.49
279_A282_D0.5510.49
553_E639_S0.5510.49
565_T611_H0.5510.49
9_V639_S0.5510.49
103_I109_G0.5490.48
318_R565_T0.5480.48
479_N482_Y0.5480.48
233_N239_E0.5470.48
393_T497_S0.5470.48
228_I235_V0.5470.48
379_I409_S0.5470.48
6_Y21_C0.5460.48
312_L548_I0.5460.48
423_K427_E0.5460.48
170_I183_V0.5460.48
127_A131_A0.5460.48
572_D575_Q0.5460.48
314_I661_V0.5460.48
177_M182_R0.5460.48
463_L474_E0.5450.48
267_A273_E0.5450.48
397_E644_L0.5450.48
130_A601_E0.5450.48
66_L69_N0.5450.48
20_T23_E0.5440.48
208_T271_K0.5440.48
150_F155_I0.5440.48
568_I610_L0.5440.48
431_V603_T0.5430.48
231_L237_E0.5430.48
244_I278_P0.5420.47
316_R390_L0.5420.47
201_P212_G0.5420.47
454_N497_S0.5420.47
256_E265_A0.5400.47
212_G215_F0.5400.47
91_E596_E0.5390.47
361_F388_T0.5390.47
517_G654_T0.5390.47
47_T343_G0.5390.47
183_V234_G0.5380.47
255_P273_E0.5380.47
550_L595_K0.5380.47
512_K545_V0.5380.47
379_I613_I0.5370.47
463_L522_V0.5360.47
559_I565_T0.5360.47
266_A275_Q0.5360.47
394_V405_L0.5360.47
264_P286_K0.5360.47
260_Q271_K0.5360.47
276_K282_D0.5350.47
398_I589_V0.5350.47
403_V508_V0.5350.47
133_A166_Y0.5340.46
398_I520_V0.5330.46
134_E148_D0.5330.46
563_I621_P0.5330.46
314_I544_S0.5330.46
200_I206_L0.5330.46
63_L96_L0.5320.46
632_Q635_V0.5320.46
90_F366_R0.5320.46
228_I232_I0.5320.46
357_V399_G0.5320.46
133_A152_R0.5310.46
89_L533_S0.5310.46
173_N239_E0.5300.46
71_L644_L0.5300.46
438_S443_F0.5300.46
299_I302_L0.5300.46
27_L128_E0.5280.46
75_R400_D0.5280.46
159_E164_K0.5280.46
313_V649_A0.5270.46
193_V228_I0.5270.46
272_Q278_P0.5260.46
161_Q280_K0.5260.46
42_F94_D0.5260.46
244_I264_P0.5250.45
101_Q104_I0.5250.45
243_V262_D0.5250.45
352_M544_S0.5240.45
137_E261_E0.5240.45
240_H277_Q0.5230.45
220_L274_K0.5230.45
58_T410_I0.5230.45
258_S261_E0.5230.45
173_N240_H0.5220.45
559_I666_D0.5210.45
92_A560_S0.5210.45
70_V79_M0.5200.45
351_N544_S0.5200.45
140_S151_E0.5200.45
561_S615_V0.5190.45
397_E512_K0.5190.45
207_E213_T0.5180.45
95_H113_I0.5180.45
345_L433_L0.5170.44
409_S493_A0.5170.44
281_N287_H0.5160.44
223_Q235_V0.5150.44
212_G216_Q0.5140.44
21_C41_I0.5140.44
267_A271_K0.5130.44
228_I236_S0.5120.44
155_I160_E0.5120.44
47_T403_V0.5120.44
346_Q349_I0.5110.44
137_E264_P0.5110.44
172_L183_V0.5110.44
166_Y232_I0.5110.44
84_D128_E0.5100.44
261_E269_P0.5100.44
216_Q614_V0.5090.43
263_S266_A0.5090.43
280_K456_K0.5080.43
630_I662_A0.5080.43
453_L532_F0.5080.43
310_E616_K0.5080.43
116_V123_N0.5080.43
219_F235_V0.5070.43
256_E278_P0.5070.43
25_L422_Q0.5060.43
316_R644_L0.5060.43
180_A232_I0.5050.43
72_D75_R0.5050.43
216_Q242_E0.5050.43
171_S202_S0.5050.43
51_M182_R0.5040.43
169_K172_L0.5040.43
131_A260_Q0.5030.43
383_I406_I0.5030.43
521_S524_S0.5030.43
23_E592_V0.5030.43
301_R318_R0.5030.43
281_N477_E0.5020.43
548_I557_I0.5020.43
53_A547_L0.5020.43
298_N349_I0.5020.43
568_I608_E0.5020.43
135_P279_A0.5010.42
354_M542_I0.5010.42
613_I631_G0.5010.42
139_Q147_Y0.5000.42
79_M454_N0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1b3qA 2 0.564 100 0.514 Contact Map
2lp4A 1 0.3304 100 0.831 Contact Map
1i58A 2 0.2812 100 0.837 Contact Map
1i5nA 1 0.192 100 0.859 Contact Map
3kyjA 1 0.1875 99.9 0.866 Contact Map
2ld6A 1 0.1949 99.9 0.869 Contact Map
2lchA 1 0.1667 99.9 0.878 Contact Map
4jpbW 1 0.1905 99.9 0.882 Contact Map
2qdlA 1 0.2039 99.9 0.887 Contact Map
2ho9A 1 0.2113 99.9 0.887 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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