GREMLIN Database
MOTB - Motility protein B
UniProt: P28612 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 261 (225)
Sequences: 4266 (3428)
Seq/√Len: 228.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
146_D153_R5.5611.00
233_S239_G3.7921.00
232_A239_G3.5641.00
234_N239_G3.4861.00
198_S224_G3.4121.00
161_K208_L3.3881.00
225_Y229_K3.2081.00
184_M240_R3.0611.00
160_A208_L2.7741.00
206_M222_A2.6521.00
236_T239_G2.6001.00
147_S184_M2.5311.00
180_H229_K2.4851.00
177_I206_M2.4731.00
150_A200_M2.4551.00
196_H207_G2.3321.00
182_D194_N2.3091.00
152_I208_L2.2551.00
110_K114_E2.2281.00
232_A242_K2.2261.00
199_V203_V2.1611.00
234_N240_R2.1151.00
22_Y26_L2.1121.00
138_T247_E2.0721.00
183_N240_R1.9521.00
148_G193_S1.8911.00
32_L36_L1.8831.00
22_Y27_T1.8351.00
108_N112_Q1.8151.00
199_V224_G1.8151.00
178_S225_Y1.7931.00
161_K212_N1.7891.00
193_S196_H1.7451.00
235_K239_G1.7351.00
42_I47_F1.6891.00
191_F200_M1.6221.00
152_I156_D1.5911.00
192_Q200_M1.5811.00
150_A191_F1.5681.00
164_S209_L1.5591.00
79_G82_E1.5301.00
178_S249_L1.5061.00
176_I223_K1.5001.00
210_I220_F1.4931.00
154_K157_V1.4801.00
54_F57_V1.4721.00
21_P25_I1.4601.00
163_I167_L1.4511.00
216_D219_V1.4461.00
21_P30_L1.4251.00
104_E107_E1.3901.00
20_V23_A1.3571.00
146_D149_K1.3561.00
176_I221_S1.3491.00
32_L35_V1.3381.00
188_N192_Q1.3301.00
208_L212_N1.3251.00
196_H200_M1.3241.00
193_S207_G1.3121.00
210_I217_A1.3051.00
232_A240_R1.2971.00
103_Q107_E1.2931.00
192_Q196_H1.2701.00
16_E19_L1.2701.00
26_L32_L1.2651.00
208_L211_E1.2411.00
230_P243_N1.2381.00
217_A228_Y1.2351.00
157_V208_L1.2321.00
160_A205_F1.2311.00
183_N234_N1.2221.00
236_T240_R1.2201.00
28_L34_I1.2191.00
43_D46_K1.2151.00
108_N111_S1.2101.00
107_E111_S1.2011.00
13_H16_E1.1911.00
160_A209_L1.1851.00
186_I191_F1.1831.00
44_A48_Q1.1801.00
136_L247_E1.1601.00
17_S21_P1.1521.00
129_K138_T1.1461.00
195_W226_G1.1431.00
203_V206_M1.1421.00
133_E136_L1.1421.00
131_T134_G1.1361.00
185_P194_N1.1361.00
203_V207_G1.1321.00
107_E110_K1.1321.00
54_F58_F1.1291.00
182_D244_R1.1211.00
178_S223_K1.1151.00
97_K101_A1.0931.00
102_D105_E1.0911.00
188_N191_F1.0871.00
215_L220_F1.0771.00
215_L219_V1.0771.00
12_E16_E1.0741.00
87_K90_K1.0631.00
206_M220_F1.0631.00
180_H226_G1.0621.00
233_S236_T1.0571.00
97_K100_A1.0531.00
14_V17_S1.0521.00
30_L34_I1.0501.00
15_D20_V1.0431.00
12_E15_D1.0371.00
17_S26_L1.0361.00
199_V222_A1.0291.00
163_I166_L1.0281.00
89_E92_K1.0231.00
200_M203_V1.0221.00
94_K98_E1.0181.00
180_H230_P1.0151.00
20_V31_A1.0101.00
102_D117_I1.0091.00
136_L249_L0.9941.00
155_E158_P0.9891.00
11_D15_D0.9851.00
147_S194_N0.9821.00
205_F246_V0.9801.00
178_S247_E0.9741.00
111_S115_K0.9701.00
147_S182_D0.9691.00
217_A227_E0.9571.00
128_T135_L0.9541.00
186_I192_Q0.9531.00
102_D106_L0.9471.00
34_I38_A0.9351.00
162_E165_N0.9301.00
78_D85_K0.9201.00
32_L38_A0.9121.00
96_E99_K0.9121.00
221_S251_L0.9111.00
152_I205_F0.9050.99
16_E21_P0.9050.99
20_V25_I0.8970.99
21_P38_A0.8960.99
81_D84_K0.8950.99
186_I193_S0.8880.99
16_E35_V0.8830.99
95_K99_K0.8780.99
185_P193_S0.8740.99
167_L215_L0.8710.99
183_N239_G0.8670.99
184_M237_A0.8650.99
44_A47_F0.8610.99
83_V87_K0.8560.99
150_A197_L0.8530.99
128_T131_T0.8380.99
11_D16_E0.8370.99
98_E102_D0.8370.99
158_P162_E0.8330.99
179_G246_V0.8300.99
207_G211_E0.8290.99
86_E89_E0.8250.99
48_Q51_S0.8250.99
159_L162_E0.8230.99
88_E91_E0.8200.99
82_E86_E0.8170.99
81_D86_E0.8120.99
239_G242_K0.8100.99
80_I84_K0.8070.99
50_L54_F0.7950.99
104_E108_N0.7920.99
145_F205_F0.7920.99
78_D83_V0.7900.99
51_S55_N0.7880.99
111_S114_E0.7870.99
13_H17_S0.7870.99
49_M52_K0.7860.99
95_K98_E0.7770.98
21_P28_L0.7740.98
195_W228_Y0.7700.98
19_L28_L0.7610.98
164_S215_L0.7590.98
78_D84_K0.7590.98
202_A224_G0.7580.98
144_F156_D0.7550.98
192_Q207_G0.7540.98
82_E85_K0.7540.98
80_I86_E0.7510.98
85_K88_E0.7460.98
134_G249_L0.7460.98
110_K130_M0.7440.98
14_V19_L0.7420.98
20_V35_V0.7380.98
81_D89_E0.7340.98
176_I249_L0.7340.98
16_E20_V0.7310.98
145_F179_G0.7270.98
105_E112_Q0.7270.98
38_A41_S0.7260.98
84_K87_K0.7260.98
194_N244_R0.7250.98
53_S57_V0.7170.97
53_S58_F0.7170.97
21_P26_L0.7130.97
133_E178_S0.7120.97
230_P240_R0.7090.97
14_V21_P0.7060.97
195_W199_V0.7040.97
52_K55_N0.7020.97
41_S44_A0.6990.97
77_S85_K0.6980.97
11_D14_V0.6960.97
106_L112_Q0.6950.97
158_P161_K0.6890.97
84_K88_E0.6850.96
145_F246_V0.6840.96
80_I87_K0.6830.96
38_A42_I0.6810.96
165_N168_V0.6790.96
186_I189_S0.6750.96
21_P32_L0.6720.96
78_D87_K0.6700.96
230_P245_R0.6700.96
101_A105_E0.6700.96
79_G86_E0.6680.96
221_S225_Y0.6650.96
112_Q170_N0.6620.96
47_F50_L0.6600.96
105_E108_N0.6570.96
25_I31_A0.6560.96
16_E26_L0.6540.95
177_I222_A0.6500.95
236_T243_N0.6500.95
21_P35_V0.6490.95
174_N253_R0.6470.95
181_T226_G0.6460.95
25_I37_Y0.6430.95
138_T231_V0.6410.95
106_L110_K0.6360.95
115_K119_D0.6320.95
18_W31_A0.6320.95
195_W222_A0.6280.94
157_V161_K0.6270.94
130_M135_L0.6260.94
231_V245_R0.6240.94
168_V215_L0.6240.94
51_S54_F0.6230.94
148_G186_I0.6230.94
152_I160_A0.6210.94
178_S229_K0.6190.94
96_E100_A0.6150.94
144_F178_S0.6120.94
116_F119_D0.6110.94
36_L39_S0.6100.93
79_G87_K0.6060.93
52_K56_E0.6010.93
180_H228_Y0.5990.93
37_Y40_S0.5970.93
100_A104_E0.5950.93
81_D85_K0.5950.93
181_T224_G0.5940.93
99_K103_Q0.5930.92
82_E88_E0.5920.92
93_N96_E0.5900.92
78_D81_D0.5890.92
31_A35_V0.5880.92
94_K97_K0.5870.92
78_D89_E0.5840.92
83_V88_E0.5800.92
148_G194_N0.5790.92
231_V242_K0.5770.91
85_K89_E0.5760.91
237_A240_R0.5740.91
31_A37_Y0.5740.91
181_T227_E0.5740.91
77_S84_K0.5700.91
181_T243_N0.5690.91
79_G90_K0.5690.91
102_D119_D0.5680.91
176_I251_L0.5660.91
139_I144_F0.5650.91
153_R158_P0.5650.91
164_S212_N0.5640.91
203_V222_A0.5630.90
152_I157_V0.5620.90
168_V214_K0.5620.90
21_P47_F0.5600.90
139_I248_V0.5600.90
138_T173_R0.5600.90
22_Y25_I0.5590.90
19_L38_A0.5590.90
129_K136_L0.5580.90
14_V26_L0.5570.90
149_K190_E0.5560.90
19_L25_I0.5560.90
133_E137_I0.5560.90
45_A49_M0.5540.90
193_S223_K0.5540.90
41_S45_A0.5540.90
109_V112_Q0.5520.90
232_A235_K0.5520.90
33_F36_L0.5520.90
77_S81_D0.5500.89
93_N97_K0.5500.89
147_S186_I0.5470.89
17_S30_L0.5460.89
157_V212_N0.5450.89
48_Q52_K0.5440.89
19_L27_T0.5430.89
206_M210_I0.5420.89
230_P236_T0.5390.88
210_I214_K0.5370.88
21_P37_Y0.5370.88
116_F120_K0.5360.88
28_L32_L0.5360.88
156_D178_S0.5350.88
118_K123_E0.5340.88
79_G83_V0.5340.88
211_E242_K0.5330.88
20_V30_L0.5330.88
83_V89_E0.5330.88
146_D151_T0.5300.88
209_L215_L0.5290.88
183_N230_P0.5230.87
80_I88_E0.5220.87
17_S25_I0.5220.87
94_K99_K0.5220.87
22_Y36_L0.5190.87
42_I46_K0.5180.86
234_N243_N0.5180.86
79_G84_K0.5160.86
183_N236_T0.5130.86
182_D185_P0.5110.86
24_D33_F0.5080.85
160_A212_N0.5070.85
106_L116_F0.5060.85
190_E200_M0.5040.85
50_L53_S0.5030.85
204_N207_G0.5030.85
79_G91_E0.5030.85
183_N237_A0.5010.85
133_E249_L0.5010.85
77_S83_V0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3wpwA 2 0.567 100 0.41 Contact Map
3s0yA 4 0.6743 100 0.449 Contact Map
4b62A 1 0.5479 100 0.451 Contact Map
3khnA 2 0.613 100 0.456 Contact Map
3ldtA 2 0.5517 100 0.462 Contact Map
2k1sA 1 0.5709 100 0.464 Contact Map
3s06A 3 0.5747 100 0.47 Contact Map
2zvyA 2 0.6475 100 0.472 Contact Map
1r1mA 1 0.4598 100 0.476 Contact Map
2zovA 2 0.5785 100 0.476 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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