GREMLIN Database
CH60 - 60 kDa chaperonin
UniProt: P28598 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 544 (531)
Sequences: 2877 (1049)
Seq/√Len: 45.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
134_S494_T5.6521.00
272_V323_V5.0101.00
476_N479_T4.8071.00
130_L494_T4.5581.00
129_N132_E4.1381.00
483_V488_K4.0181.00
457_L475_F3.8531.00
462_I482_W3.8471.00
476_N483_V3.7891.00
429_A437_I3.7581.00
475_F480_G3.7351.00
448_I466_L3.4551.00
484_N487_E3.4351.00
336_E339_K3.3281.00
119_M505_A3.3241.00
465_R468_N3.2751.00
50_N55_I3.1621.00
120_E509_A3.0971.00
20_D24_D3.0441.00
425_A441_L2.8511.00
121_Q433_A2.8061.00
123_V505_A2.7891.00
285_A288_E2.7581.00
424_V437_I2.7031.00
337_T341_S2.6541.00
17_R66_E2.6481.00
17_R21_A2.6481.00
483_V490_I2.6251.00
16_L20_D2.6191.00
164_M405_V2.6101.00
215_N243_K2.5471.00
324_T327_N2.5021.00
20_D96_Q2.4921.00
248_I290_I2.4771.00
457_L480_G2.4461.00
220_I296_G2.4421.00
114_G433_A2.4401.00
144_A158_S2.4341.00
130_L416_A2.4271.00
27_K96_Q2.4231.00
211_A272_V2.3931.00
213_L246_L2.3601.00
98_M119_M2.2991.00
14_A17_R2.2941.00
126_A444_L2.2941.00
392_L395_E2.2881.00
417_L497_T2.2801.00
45_S385_T2.2371.00
485_M490_I2.1911.00
99_I511_F2.1841.00
71_K74_A2.1651.00
101_E442_R2.1581.00
445_E467_K2.1571.00
142_S145_Q2.1441.00
297_E314_Q2.1261.00
9_E13_R2.1241.00
418_V448_I2.1201.00
427_V430_E2.1181.00
357_E360_R2.1011.00
476_N490_I2.0851.00
116_R120_E2.0710.99
427_V431_G2.0510.99
5_I516_A2.0440.99
319_S332_E2.0420.99
452_A459_G2.0390.99
39_L518_V2.0360.99
426_A430_E2.0280.99
311_Q314_Q2.0120.99
140_K165_E2.0010.99
299_I310_T1.9950.99
237_Q311_Q1.9630.99
318_A330_I1.9490.99
469_E473_V1.9460.99
452_A457_L1.9430.99
105_N435_T1.9260.99
220_I290_I1.9240.99
125_V128_E1.9170.99
409_I491_V1.9060.99
154_E158_S1.8940.99
354_T360_R1.8740.99
124_A128_E1.8580.99
47_L392_L1.8560.99
139_G142_S1.8230.99
119_M440_V1.8160.99
528_G531_M1.8120.99
158_S162_E1.8090.99
4_E521_K1.8030.99
24_D96_Q1.7900.98
347_I367_L1.7830.98
415_T419_N1.7770.98
19_V511_F1.7680.98
184_E378_K1.7630.98
100_R446_E1.7570.98
529_A532_P1.7490.98
105_N110_A1.7490.98
98_M440_V1.7490.98
351_V367_L1.7390.98
135_K142_S1.7310.98
419_N471_I1.7190.98
418_V467_K1.7080.98
81_N392_L1.7040.98
129_N133_I1.7030.98
138_E142_S1.6870.98
122_A440_V1.6630.98
218_I318_A1.6560.97
426_A437_I1.6490.97
217_Y317_R1.6450.97
193_F274_V1.6400.97
472_G484_N1.6330.97
81_N399_N1.6320.97
243_K317_R1.6310.97
128_E132_E1.6230.97
126_A420_V1.6210.97
226_T253_E1.6170.97
445_E449_R1.6070.97
434_Q438_N1.5680.96
317_R334_A1.5510.96
129_N423_K1.5490.96
464_E468_N1.5370.96
4_E519_A1.5360.96
381_A387_L1.5350.96
237_Q240_Q1.5230.96
68_M519_A1.5110.96
62_E524_E1.5070.96
438_N441_L1.5010.95
428_E431_G1.4960.95
68_M517_V1.4890.95
6_K65_F1.4870.95
527_G530_G1.4750.95
448_I452_A1.4640.95
451_I477_A1.4480.94
392_L399_N1.4470.94
526_G529_A1.4330.94
424_V441_L1.4280.94
465_R469_E1.4230.94
186_E378_K1.4230.94
348_R371_A1.4220.94
110_A435_T1.4210.94
344_V371_A1.4120.94
20_D100_R1.4090.94
114_G478_A1.3970.93
398_L402_R1.3970.93
220_I248_I1.3920.93
419_N472_G1.3770.93
140_K162_E1.3760.93
65_F519_A1.3720.93
476_N488_K1.3710.93
81_N395_E1.3670.93
246_L323_V1.3660.93
42_K64_A1.3640.93
135_K486_I1.3530.92
50_N392_L1.3380.92
110_A432_D1.3330.92
131_K498_R1.3220.91
351_V357_E1.3210.91
4_E520_D1.3160.91
14_A63_D1.3120.91
114_G117_K1.3050.91
215_N317_R1.3050.91
442_R446_E1.3030.91
421_Y444_L1.2990.91
341_S345_T1.2970.90
62_E521_K1.2900.90
126_A424_V1.2870.90
216_P318_A1.2860.90
426_A431_G1.2850.90
16_L103_L1.2850.90
205_D208_K1.2800.90
321_V330_I1.2750.90
406_E495_K1.2750.90
361_E364_Q1.2720.90
41_K58_E1.2610.89
498_R502_Q1.2600.89
220_I298_V1.2600.89
338_D341_S1.2590.89
65_F517_V1.2540.89
214_D320_K1.2520.89
264_K270_N1.2500.89
362_K365_E1.2480.89
339_K342_A1.2460.89
428_E434_Q1.2450.89
128_E131_K1.2440.89
170_D348_R1.2440.89
223_K301_E1.2390.88
197_Y209_M1.2380.88
205_D212_V1.2300.88
418_V421_Y1.2260.88
222_D310_T1.2250.88
141_E487_E1.2220.88
127_I131_K1.2170.87
120_E124_A1.2170.87
389_E393_R1.2140.87
127_I502_Q1.2080.87
306_D309_S1.2040.87
212_V320_K1.2030.87
125_V423_K1.1980.87
198_A252_V1.1960.86
457_L462_I1.1930.86
264_K267_G1.1880.86
338_D342_A1.1840.86
419_N466_L1.1830.86
299_I305_L1.1610.85
290_I330_I1.1600.85
49_T389_E1.1590.85
258_A262_V1.1570.85
133_I136_P1.1570.85
163_A185_L1.1520.84
464_E467_K1.1500.84
305_L314_Q1.1380.84
213_L272_V1.1320.83
511_F517_V1.1140.82
466_L469_E1.1130.82
16_L100_R1.1110.82
310_T314_Q1.1060.82
166_R189_E1.1050.82
299_I314_Q1.1020.82
481_E488_K1.0990.81
421_Y467_K1.0990.81
178_S387_L1.0980.81
250_E283_R1.0980.81
524_E527_G1.0970.81
227_N230_E1.0930.81
520_D523_E1.0870.81
422_N425_A1.0840.81
140_K158_S1.0840.81
335_G340_I1.0800.80
427_V434_Q1.0800.80
80_T503_N1.0770.80
407_E498_R1.0650.79
55_I392_L1.0610.79
521_K526_G1.0590.79
344_V348_R1.0590.79
148_A154_E1.0580.79
247_L271_A1.0570.79
21_A66_E1.0520.78
164_M173_I1.0510.78
466_L482_W1.0500.78
246_L272_V1.0460.78
522_P526_G1.0320.77
430_E437_I1.0280.77
345_T349_A1.0270.77
144_A147_A1.0230.76
251_D275_K1.0190.76
228_I259_T1.0160.76
146_V409_I1.0020.75
211_A323_V1.0010.75
305_L310_T1.0000.75
130_L420_V0.9990.75
49_T392_L0.9980.75
288_E339_K0.9970.75
426_A429_A0.9950.74
216_P321_V0.9940.74
528_G532_P0.9810.73
427_V437_I0.9810.73
125_V132_E0.9790.73
471_I484_N0.9790.73
121_Q429_A0.9770.73
191_M293_L0.9750.73
318_A321_V0.9730.73
27_K450_Q0.9720.73
119_M436_G0.9720.73
466_L473_V0.9700.73
223_K296_G0.9700.73
282_R359_D0.9670.72
217_Y243_K0.9630.72
527_G531_M0.9610.72
288_E350_Q0.9590.72
350_Q353_E0.9580.72
77_A92_T0.9540.71
10_E14_A0.9390.70
288_E292_V0.9320.70
221_T225_I0.9310.69
6_K14_A0.9300.69
473_V483_V0.9280.69
22_L73_V0.9240.69
465_R473_V0.9210.69
448_I463_V0.9200.68
159_L185_L0.9200.68
428_E437_I0.9190.68
23_A96_Q0.9160.68
432_D435_T0.9160.68
217_Y241_Q0.9160.68
278_G286_M0.9120.68
179_K183_T0.9110.68
288_E303_L0.9100.68
282_R365_E0.9040.67
39_L58_E0.9020.67
48_I385_T0.9010.67
40_E65_F0.8990.67
222_D305_L0.8950.66
434_Q437_I0.8900.66
117_K120_E0.8890.66
149_I152_A0.8880.66
479_T490_I0.8840.65
242_G270_N0.8820.65
133_I420_V0.8790.65
241_Q244_P0.8770.65
110_A431_G0.8750.65
324_T378_K0.8740.64
155_E183_T0.8730.64
298_V303_L0.8730.64
418_V463_V0.8720.64
345_T348_R0.8650.64
259_T262_V0.8640.64
300_T303_L0.8630.63
469_E482_W0.8620.63
234_V310_T0.8600.63
106_V115_V0.8590.63
192_Q327_N0.8590.63
123_V501_L0.8590.63
218_I330_I0.8590.63
123_V440_V0.8590.63
132_E470_E0.8570.63
173_I405_V0.8570.63
218_I246_L0.8530.63
129_N420_V0.8490.62
520_D526_G0.8450.62
49_T74_A0.8450.62
40_E520_D0.8450.62
305_L309_S0.8440.62
349_A353_E0.8440.62
458_E463_V0.8420.62
55_I202_M0.8410.61
51_D54_T0.8390.61
16_L99_I0.8390.61
113_V509_A0.8380.61
14_A66_E0.8300.60
42_K523_E0.8270.60
222_D298_V0.8250.60
381_A512_L0.8220.60
241_Q312_I0.8210.60
262_V266_R0.8160.59
10_E13_R0.8120.59
39_L54_T0.8080.58
421_Y445_E0.8020.58
523_E526_G0.8010.58
47_L395_E0.8000.58
238_V245_L0.8000.58
418_V445_E0.8000.58
203_V209_M0.7970.57
122_A437_I0.7920.57
61_L66_E0.7920.57
521_K525_N0.7910.57
4_E14_A0.7900.57
319_S334_A0.7880.56
476_N485_M0.7880.56
288_E346_Q0.7850.56
245_L271_A0.7820.56
13_R16_L0.7820.56
36_N513_T0.7750.55
180_G319_S0.7740.55
445_E458_E0.7740.55
217_Y238_V0.7720.55
483_V487_E0.7710.55
73_V511_F0.7700.55
17_R20_D0.7690.55
476_N481_E0.7660.54
526_G530_G0.7660.54
64_A175_I0.7630.54
7_F181_F0.7600.54
431_G434_Q0.7590.54
228_I232_L0.7580.54
299_I311_Q0.7570.53
416_A420_V0.7570.53
300_T305_L0.7560.53
19_V73_V0.7560.53
178_S228_I0.7540.53
449_R460_S0.7540.53
252_V273_A0.7530.53
411_S415_T0.7520.53
6_K10_E0.7510.53
422_N467_K0.7500.53
53_V56_A0.7480.53
503_N512_L0.7460.52
526_G531_M0.7460.52
420_V444_L0.7440.52
291_A296_G0.7420.52
54_T58_E0.7410.52
15_M99_I0.7410.52
437_I441_L0.7390.52
136_P139_G0.7370.52
6_K517_V0.7360.51
147_A248_I0.7360.51
125_V437_I0.7350.51
121_Q437_I0.7350.51
349_A352_E0.7350.51
344_V367_L0.7340.51
28_V516_A0.7340.51
422_N470_E0.7330.51
261_V402_R0.7320.51
133_I411_S0.7320.51
463_V466_L0.7300.51
442_R445_E0.7270.51
64_A522_P0.7270.51
6_K40_E0.7270.51
322_V331_V0.7270.51
98_M511_F0.7260.50
452_A462_I0.7240.50
20_D23_A0.7230.50
296_G314_Q0.7230.50
416_A494_T0.7230.50
2_A5_I0.7220.50
71_K402_R0.7220.50
208_K491_V0.7160.49
181_F184_E0.7160.49
115_V440_V0.7150.49
234_V238_V0.7130.49
180_G432_D0.7110.49
431_G435_T0.7110.49
117_K433_A0.7080.49
288_E302_D0.7070.49
440_V444_L0.7060.48
246_L253_E0.7060.48
25_A516_A0.7060.48
526_G532_P0.7010.48
13_R387_L0.7000.48
429_A434_Q0.6980.48
160_I377_I0.6960.48
159_L183_T0.6960.48
470_E473_V0.6960.48
99_I222_D0.6950.47
499_S502_Q0.6930.47
125_V427_V0.6930.47
213_L321_V0.6920.47
40_E240_Q0.6910.47
274_V323_V0.6900.47
33_K480_G0.6870.47
181_F382_A0.6860.47
415_T466_L0.6860.47
141_E390_R0.6820.46
121_Q125_V0.6820.46
18_G69_G0.6810.46
188_V398_L0.6800.46
324_T329_T0.6800.46
4_E64_A0.6800.46
221_T250_E0.6790.46
98_M505_A0.6780.46
30_L90_T0.6760.46
178_S181_F0.6750.45
216_P243_K0.6740.45
292_V324_T0.6730.45
446_E449_R0.6710.45
438_N442_R0.6710.45
354_T367_L0.6700.45
331_V515_E0.6700.45
57_K223_K0.6690.45
68_M398_L0.6690.45
140_K161_A0.6680.45
426_A441_L0.6680.45
440_V490_I0.6680.45
21_A62_E0.6680.45
143_I405_V0.6680.45
226_T252_V0.6670.45
50_N202_M0.6670.45
440_V505_A0.6670.45
249_A252_V0.6650.44
162_E166_R0.6640.44
525_N530_G0.6640.44
19_V99_I0.6640.44
497_T516_A0.6640.44
462_I477_A0.6640.44
65_F68_M0.6630.44
213_L244_P0.6630.44
341_S344_V0.6620.44
276_A287_L0.6620.44
473_V482_W0.6610.44
131_K134_S0.6590.44
118_G436_G0.6590.44
155_E162_E0.6580.44
12_R515_E0.6570.44
131_K494_T0.6570.44
113_V116_R0.6570.44
55_I399_N0.6560.44
2_A491_V0.6550.44
2_A521_K0.6550.44
15_M21_A0.6550.44
521_K527_G0.6550.44
126_A425_A0.6530.43
244_P510_M0.6490.43
128_E238_V0.6490.43
126_A441_L0.6470.43
424_V427_V0.6460.43
4_E13_R0.6460.43
39_L59_I0.6450.43
67_N71_K0.6450.43
38_V55_I0.6450.43
207_D388_K0.6440.42
175_I394_I0.6440.42
381_A390_R0.6420.42
182_T202_M0.6410.42
410_V416_A0.6400.42
147_A405_V0.6400.42
64_A523_E0.6400.42
246_L274_V0.6400.42
198_A251_D0.6390.42
81_N499_S0.6370.42
124_A502_Q0.6360.42
388_K395_E0.6350.42
238_V242_G0.6340.42
150_S376_V0.6330.41
415_T473_V0.6330.41
346_Q353_E0.6320.41
288_E300_T0.6310.41
291_A298_V0.6310.41
111_N405_V0.6300.41
134_S334_A0.6300.41
179_K182_T0.6290.41
152_A232_L0.6290.41
446_E450_Q0.6290.41
104_K293_L0.6280.41
377_I517_V0.6280.41
527_G532_P0.6270.41
265_L479_T0.6260.41
431_G437_I0.6250.41
231_I234_V0.6250.41
219_L245_L0.6240.41
68_M71_K0.6240.41
178_S184_E0.6230.40
132_E428_E0.6200.40
221_T231_I0.6190.40
421_Y441_L0.6190.40
316_G408_G0.6180.40
376_V507_V0.6180.40
110_A517_V0.6180.40
41_K47_L0.6170.40
215_N319_S0.6170.40
83_V499_S0.6160.40
49_T55_I0.6150.40
143_I164_M0.6150.40
38_V511_F0.6140.40
42_K507_V0.6140.40
420_V423_K0.6140.40
433_A437_I0.6130.40
222_D300_T0.6130.40
417_L421_Y0.6120.39
136_P142_S0.6110.39
50_N99_I0.6110.39
159_L443_A0.6110.39
479_T483_V0.6100.39
237_Q312_I0.6100.39
284_K302_D0.6090.39
15_M517_V0.6070.39
93_V446_E0.6070.39
419_N469_E0.6060.39
125_V129_N0.6060.39
246_L321_V0.6050.39
425_A438_N0.6050.39
6_K9_E0.6050.39
389_E392_L0.6050.39
433_A446_E0.6020.39
229_Q281_D0.6020.39
143_I406_E0.6000.38
205_D210_E0.5980.38
244_P323_V0.5980.38
50_N152_A0.5950.38
73_V76_V0.5950.38
389_E420_V0.5950.38
21_A470_E0.5940.38
177_E387_L0.5940.38
39_L258_A0.5940.38
81_N147_A0.5930.38
99_I437_I0.5930.38
70_A91_A0.5920.38
152_A239_V0.5920.38
151_A157_G0.5910.37
366_R408_G0.5900.37
185_L246_L0.5890.37
244_P272_V0.5890.37
212_V322_V0.5890.37
525_N528_G0.5890.37
104_K108_A0.5880.37
392_L420_V0.5880.37
424_V468_N0.5870.37
289_D408_G0.5850.37
212_V271_A0.5850.37
6_K98_M0.5840.37
176_E282_R0.5840.37
383_T507_V0.5840.37
105_N108_A0.5830.37
222_D358_F0.5830.37
114_G432_D0.5820.37
16_L511_F0.5810.37
164_M401_T0.5800.36
126_A423_K0.5790.36
98_M439_I0.5790.36
73_V84_A0.5780.36
289_D366_R0.5780.36
72_L387_L0.5770.36
415_T448_I0.5760.36
123_V127_I0.5750.36
49_T89_T0.5740.36
440_V508_A0.5730.36
7_F17_R0.5730.36
140_K182_T0.5730.36
8_S62_E0.5730.36
118_G489_G0.5720.36
419_N422_N0.5720.36
164_M398_L0.5720.36
139_G490_I0.5720.36
155_E462_I0.5710.36
106_V478_A0.5700.36
419_N473_V0.5700.36
309_S323_V0.5680.35
133_I416_A0.5680.35
322_V490_I0.5680.35
220_I324_T0.5670.35
159_L214_D0.5660.35
217_Y312_I0.5660.35
126_A129_N0.5660.35
255_E259_T0.5650.35
115_V424_V0.5640.35
130_L445_E0.5640.35
22_L91_A0.5640.35
418_V510_M0.5640.35
304_G307_L0.5630.35
33_K59_I0.5630.35
282_R361_E0.5620.35
8_S511_F0.5620.35
336_E434_Q0.5620.35
342_A354_T0.5610.35
336_E341_S0.5610.35
246_L348_R0.5600.35
148_A175_I0.5600.35
105_N512_L0.5580.35
65_F458_E0.5580.35
170_D231_I0.5570.34
262_V384_E0.5560.34
208_K228_I0.5550.34
429_A433_A0.5540.34
465_R481_E0.5540.34
13_R17_R0.5540.34
178_S207_D0.5530.34
442_R449_R0.5530.34
149_I490_I0.5530.34
167_V171_G0.5530.34
296_G339_K0.5520.34
47_L238_V0.5510.34
235_L263_N0.5510.34
415_T475_F0.5500.34
201_Y325_K0.5490.34
57_K201_Y0.5490.34
89_T396_D0.5490.34
181_F378_K0.5480.34
298_V305_L0.5470.34
100_R502_Q0.5470.34
297_E305_L0.5470.34
62_E66_E0.5460.33
225_I231_I0.5460.33
76_V458_E0.5450.33
218_I321_V0.5450.33
165_E516_A0.5450.33
186_E527_G0.5450.33
92_T495_K0.5450.33
338_D453_H0.5440.33
21_A170_D0.5440.33
148_A322_V0.5430.33
54_T214_D0.5430.33
288_E297_E0.5430.33
6_K521_K0.5420.33
174_T376_V0.5410.33
93_V97_A0.5410.33
169_N395_E0.5410.33
133_I471_I0.5410.33
227_N430_E0.5410.33
97_A446_E0.5400.33
99_I510_M0.5400.33
68_M180_G0.5390.33
57_K78_S0.5380.33
231_I312_I0.5380.33
298_V310_T0.5380.33
452_A455_A0.5370.33
459_G463_V0.5370.33
15_M319_S0.5370.33
129_N422_N0.5370.33
71_K517_V0.5370.33
81_N149_I0.5360.33
54_T459_G0.5360.33
340_I355_T0.5360.33
403_A407_E0.5360.33
399_N509_A0.5360.33
448_I482_W0.5360.33
145_Q185_L0.5350.33
176_E304_G0.5350.33
144_A154_E0.5350.33
433_A483_V0.5340.32
230_E268_T0.5340.32
474_G485_M0.5340.32
107_T466_L0.5330.32
99_I272_V0.5330.32
231_I269_F0.5330.32
140_K159_L0.5330.32
525_N529_A0.5320.32
332_E335_G0.5320.32
114_G195_R0.5320.32
139_G420_V0.5320.32
262_V300_T0.5320.32
80_T409_I0.5320.32
168_G417_L0.5320.32
76_V91_A0.5310.32
470_E487_E0.5310.32
47_L81_N0.5310.32
445_E460_S0.5300.32
228_I348_R0.5300.32
449_R453_H0.5300.32
281_D284_K0.5300.32
460_S464_E0.5300.32
43_F111_N0.5290.32
192_Q203_V0.5290.32
234_V302_D0.5290.32
252_V443_A0.5290.32
55_I105_N0.5280.32
162_E347_I0.5280.32
56_A88_T0.5280.32
132_E336_E0.5270.32
15_M68_M0.5270.32
258_A363_L0.5270.32
137_I155_E0.5270.32
69_G474_G0.5260.32
8_S103_L0.5260.32
430_E434_Q0.5260.32
283_R359_D0.5250.32
183_T390_R0.5250.32
481_E487_E0.5240.32
277_P380_G0.5240.32
33_K64_A0.5240.32
446_E453_H0.5240.32
191_M369_K0.5230.31
204_T264_K0.5230.31
96_Q116_R0.5220.31
121_Q214_D0.5220.31
36_N152_A0.5220.31
347_I363_L0.5220.31
55_I59_I0.5210.31
171_G447_P0.5200.31
333_G336_E0.5200.31
110_A137_I0.5190.31
55_I99_I0.5190.31
72_L507_V0.5190.31
159_L377_I0.5180.31
216_P317_R0.5180.31
38_V324_T0.5170.31
24_D28_V0.5170.31
200_P390_R0.5170.31
387_L390_R0.5160.31
121_Q484_N0.5160.31
133_I419_N0.5150.31
200_P258_A0.5150.31
336_E443_A0.5150.31
410_V494_T0.5140.31
166_R187_V0.5140.31
228_I231_I0.5140.31
4_E522_P0.5140.31
162_E342_A0.5130.31
124_A433_A0.5130.31
472_G486_I0.5120.31
278_G281_D0.5120.31
76_V96_Q0.5120.31
183_T187_V0.5110.30
84_A178_S0.5110.30
163_A323_V0.5100.30
50_N389_E0.5100.30
14_A237_Q0.5090.30
114_G518_V0.5090.30
40_E64_A0.5090.30
6_K519_A0.5090.30
351_V364_Q0.5090.30
185_L192_Q0.5080.30
313_A339_K0.5080.30
15_M208_K0.5070.30
472_G497_T0.5070.30
260_L271_A0.5070.30
21_A218_I0.5070.30
207_D349_A0.5070.30
321_V528_G0.5060.30
37_V516_A0.5060.30
52_G56_A0.5040.30
344_V422_N0.5040.30
59_I518_V0.5040.30
56_A389_E0.5030.30
63_D432_D0.5030.30
239_V268_T0.5030.30
232_L239_V0.5030.30
194_D359_D0.5030.30
104_K107_T0.5030.30
212_V438_N0.5020.30
265_L409_I0.5020.30
391_K451_I0.5020.30
143_I173_I0.5020.30
16_L159_L0.5020.30
301_E309_S0.5020.30
146_V400_S0.5020.30
448_I464_E0.5020.30
79_K83_V0.5010.30
152_A183_T0.5010.30
236_E240_Q0.5000.30
522_P527_G0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1kp8A 5 0.9614 100 0.165 Contact Map
1iokA 5 0.8805 100 0.169 Contact Map
3rtkA 2 0.8254 100 0.174 Contact Map
1we3A 5 0.9614 100 0.184 Contact Map
4pj1A 6 0.9596 100 0.213 Contact Map
3ruvA 6 0.8401 100 0.337 Contact Map
1q3qA 4 0.8419 100 0.342 Contact Map
1a6dA 2 0.8309 100 0.35 Contact Map
3p9dC 1 0.8382 100 0.353 Contact Map
3j1bA 4 0.8382 100 0.358 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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