CH60 - BACSU - GREMLIN Contacts

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CH60 - 60 kDa chaperonin

UniProt:	P28598	Sequences: MAKEIKFSEEARRAMLRGVDALADAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPVGVRKGMEQAVAVAIENLKEISKPIEGKESIAQVAAISAADEEVGSLIAEAMERVGNDGVITIEESKGFTTELEVVEGMQFDRGYASPYMVTDSDKMEAVLDNPYILITDKKITNIQEILPVLEQVVQQGKPLLLIAEDVEGEALATLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDIAVLTGGEVITEDLGLDLKSTQIAQLGRASKVVVTKENTTIVEGAGETDKISARVTQIRAQVEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVSGGGTALVNVYNKVAAVEAEGDAQTGINIVLRALEEPIRQIAHNAGLEGSVIVERLKNEEIGVGFNAATGEWVNMIEKGIVDPTKVTRSALQNAASVAAMFLTTEAVVADKPEENGGGAGMPDMGGMGGMGGMM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	544 (531)
Sequences:	2877 (1049)
Seq/√Len:	45.5

ECOLI - CH60
BACSU - CH60
HALSA - THSA
SULSO - THSG THSB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
134_S	494_T	5.652	1.00
272_V	323_V	5.010	1.00
476_N	479_T	4.807	1.00
130_L	494_T	4.558	1.00
129_N	132_E	4.138	1.00
483_V	488_K	4.018	1.00
457_L	475_F	3.853	1.00
462_I	482_W	3.847	1.00
476_N	483_V	3.789	1.00
429_A	437_I	3.758	1.00
475_F	480_G	3.735	1.00
448_I	466_L	3.455	1.00
484_N	487_E	3.435	1.00
336_E	339_K	3.328	1.00
119_M	505_A	3.324	1.00
465_R	468_N	3.275	1.00
50_N	55_I	3.162	1.00
120_E	509_A	3.097	1.00
20_D	24_D	3.044	1.00
425_A	441_L	2.851	1.00
121_Q	433_A	2.806	1.00
123_V	505_A	2.789	1.00
285_A	288_E	2.758	1.00
424_V	437_I	2.703	1.00
337_T	341_S	2.654	1.00
17_R	66_E	2.648	1.00
17_R	21_A	2.648	1.00
483_V	490_I	2.625	1.00
16_L	20_D	2.619	1.00
164_M	405_V	2.610	1.00
215_N	243_K	2.547	1.00
324_T	327_N	2.502	1.00
20_D	96_Q	2.492	1.00
248_I	290_I	2.477	1.00
457_L	480_G	2.446	1.00
220_I	296_G	2.442	1.00
114_G	433_A	2.440	1.00
144_A	158_S	2.434	1.00
130_L	416_A	2.427	1.00
27_K	96_Q	2.423	1.00
211_A	272_V	2.393	1.00
213_L	246_L	2.360	1.00
98_M	119_M	2.299	1.00
14_A	17_R	2.294	1.00
126_A	444_L	2.294	1.00
392_L	395_E	2.288	1.00
417_L	497_T	2.280	1.00
45_S	385_T	2.237	1.00
485_M	490_I	2.191	1.00
99_I	511_F	2.184	1.00
71_K	74_A	2.165	1.00
101_E	442_R	2.158	1.00
445_E	467_K	2.157	1.00
142_S	145_Q	2.144	1.00
297_E	314_Q	2.126	1.00
9_E	13_R	2.124	1.00
418_V	448_I	2.120	1.00
427_V	430_E	2.118	1.00
357_E	360_R	2.101	1.00
476_N	490_I	2.085	1.00
116_R	120_E	2.071	0.99
427_V	431_G	2.051	0.99
5_I	516_A	2.044	0.99
319_S	332_E	2.042	0.99
452_A	459_G	2.039	0.99
39_L	518_V	2.036	0.99
426_A	430_E	2.028	0.99
311_Q	314_Q	2.012	0.99
140_K	165_E	2.001	0.99
299_I	310_T	1.995	0.99
237_Q	311_Q	1.963	0.99
318_A	330_I	1.949	0.99
469_E	473_V	1.946	0.99
452_A	457_L	1.943	0.99
105_N	435_T	1.926	0.99
220_I	290_I	1.924	0.99
125_V	128_E	1.917	0.99
409_I	491_V	1.906	0.99
154_E	158_S	1.894	0.99
354_T	360_R	1.874	0.99
124_A	128_E	1.858	0.99
47_L	392_L	1.856	0.99
139_G	142_S	1.823	0.99
119_M	440_V	1.816	0.99
528_G	531_M	1.812	0.99
158_S	162_E	1.809	0.99
4_E	521_K	1.803	0.99
24_D	96_Q	1.790	0.98
347_I	367_L	1.783	0.98
415_T	419_N	1.777	0.98
19_V	511_F	1.768	0.98
184_E	378_K	1.763	0.98
100_R	446_E	1.757	0.98
529_A	532_P	1.749	0.98
105_N	110_A	1.749	0.98
98_M	440_V	1.749	0.98
351_V	367_L	1.739	0.98
135_K	142_S	1.731	0.98
419_N	471_I	1.719	0.98
418_V	467_K	1.708	0.98
81_N	392_L	1.704	0.98
129_N	133_I	1.703	0.98
138_E	142_S	1.687	0.98
122_A	440_V	1.663	0.98
218_I	318_A	1.656	0.97
426_A	437_I	1.649	0.97
217_Y	317_R	1.645	0.97
193_F	274_V	1.640	0.97
472_G	484_N	1.633	0.97
81_N	399_N	1.632	0.97
243_K	317_R	1.631	0.97
128_E	132_E	1.623	0.97
126_A	420_V	1.621	0.97
226_T	253_E	1.617	0.97
445_E	449_R	1.607	0.97
434_Q	438_N	1.568	0.96
317_R	334_A	1.551	0.96
129_N	423_K	1.549	0.96
464_E	468_N	1.537	0.96
4_E	519_A	1.536	0.96
381_A	387_L	1.535	0.96
237_Q	240_Q	1.523	0.96
68_M	519_A	1.511	0.96
62_E	524_E	1.507	0.96
438_N	441_L	1.501	0.95
428_E	431_G	1.496	0.95
68_M	517_V	1.489	0.95
6_K	65_F	1.487	0.95
527_G	530_G	1.475	0.95
448_I	452_A	1.464	0.95
451_I	477_A	1.448	0.94
392_L	399_N	1.447	0.94
526_G	529_A	1.433	0.94
424_V	441_L	1.428	0.94
465_R	469_E	1.423	0.94
186_E	378_K	1.423	0.94
348_R	371_A	1.422	0.94
110_A	435_T	1.421	0.94
344_V	371_A	1.412	0.94
20_D	100_R	1.409	0.94
114_G	478_A	1.397	0.93
398_L	402_R	1.397	0.93
220_I	248_I	1.392	0.93
419_N	472_G	1.377	0.93
140_K	162_E	1.376	0.93
65_F	519_A	1.372	0.93
476_N	488_K	1.371	0.93
81_N	395_E	1.367	0.93
246_L	323_V	1.366	0.93
42_K	64_A	1.364	0.93
135_K	486_I	1.353	0.92
50_N	392_L	1.338	0.92
110_A	432_D	1.333	0.92
131_K	498_R	1.322	0.91
351_V	357_E	1.321	0.91
4_E	520_D	1.316	0.91
14_A	63_D	1.312	0.91
114_G	117_K	1.305	0.91
215_N	317_R	1.305	0.91
442_R	446_E	1.303	0.91
421_Y	444_L	1.299	0.91
341_S	345_T	1.297	0.90
62_E	521_K	1.290	0.90
126_A	424_V	1.287	0.90
216_P	318_A	1.286	0.90
426_A	431_G	1.285	0.90
16_L	103_L	1.285	0.90
205_D	208_K	1.280	0.90
321_V	330_I	1.275	0.90
406_E	495_K	1.275	0.90
361_E	364_Q	1.272	0.90
41_K	58_E	1.261	0.89
498_R	502_Q	1.260	0.89
220_I	298_V	1.260	0.89
338_D	341_S	1.259	0.89
65_F	517_V	1.254	0.89
214_D	320_K	1.252	0.89
264_K	270_N	1.250	0.89
362_K	365_E	1.248	0.89
339_K	342_A	1.246	0.89
428_E	434_Q	1.245	0.89
128_E	131_K	1.244	0.89
170_D	348_R	1.244	0.89
223_K	301_E	1.239	0.88
197_Y	209_M	1.238	0.88
205_D	212_V	1.230	0.88
418_V	421_Y	1.226	0.88
222_D	310_T	1.225	0.88
141_E	487_E	1.222	0.88
127_I	131_K	1.217	0.87
120_E	124_A	1.217	0.87
389_E	393_R	1.214	0.87
127_I	502_Q	1.208	0.87
306_D	309_S	1.204	0.87
212_V	320_K	1.203	0.87
125_V	423_K	1.198	0.87
198_A	252_V	1.196	0.86
457_L	462_I	1.193	0.86
264_K	267_G	1.188	0.86
338_D	342_A	1.184	0.86
419_N	466_L	1.183	0.86
299_I	305_L	1.161	0.85
290_I	330_I	1.160	0.85
49_T	389_E	1.159	0.85
258_A	262_V	1.157	0.85
133_I	136_P	1.157	0.85
163_A	185_L	1.152	0.84
464_E	467_K	1.150	0.84
305_L	314_Q	1.138	0.84
213_L	272_V	1.132	0.83
511_F	517_V	1.114	0.82
466_L	469_E	1.113	0.82
16_L	100_R	1.111	0.82
310_T	314_Q	1.106	0.82
166_R	189_E	1.105	0.82
299_I	314_Q	1.102	0.82
481_E	488_K	1.099	0.81
421_Y	467_K	1.099	0.81
178_S	387_L	1.098	0.81
250_E	283_R	1.098	0.81
524_E	527_G	1.097	0.81
227_N	230_E	1.093	0.81
520_D	523_E	1.087	0.81
422_N	425_A	1.084	0.81
140_K	158_S	1.084	0.81
335_G	340_I	1.080	0.80
427_V	434_Q	1.080	0.80
80_T	503_N	1.077	0.80
407_E	498_R	1.065	0.79
55_I	392_L	1.061	0.79
521_K	526_G	1.059	0.79
344_V	348_R	1.059	0.79
148_A	154_E	1.058	0.79
247_L	271_A	1.057	0.79
21_A	66_E	1.052	0.78
164_M	173_I	1.051	0.78
466_L	482_W	1.050	0.78
246_L	272_V	1.046	0.78
522_P	526_G	1.032	0.77
430_E	437_I	1.028	0.77
345_T	349_A	1.027	0.77
144_A	147_A	1.023	0.76
251_D	275_K	1.019	0.76
228_I	259_T	1.016	0.76
146_V	409_I	1.002	0.75
211_A	323_V	1.001	0.75
305_L	310_T	1.000	0.75
130_L	420_V	0.999	0.75
49_T	392_L	0.998	0.75
288_E	339_K	0.997	0.75
426_A	429_A	0.995	0.74
216_P	321_V	0.994	0.74
528_G	532_P	0.981	0.73
427_V	437_I	0.981	0.73
125_V	132_E	0.979	0.73
471_I	484_N	0.979	0.73
121_Q	429_A	0.977	0.73
191_M	293_L	0.975	0.73
318_A	321_V	0.973	0.73
27_K	450_Q	0.972	0.73
119_M	436_G	0.972	0.73
466_L	473_V	0.970	0.73
223_K	296_G	0.970	0.73
282_R	359_D	0.967	0.72
217_Y	243_K	0.963	0.72
527_G	531_M	0.961	0.72
288_E	350_Q	0.959	0.72
350_Q	353_E	0.958	0.72
77_A	92_T	0.954	0.71
10_E	14_A	0.939	0.70
288_E	292_V	0.932	0.70
221_T	225_I	0.931	0.69
6_K	14_A	0.930	0.69
473_V	483_V	0.928	0.69
22_L	73_V	0.924	0.69
465_R	473_V	0.921	0.69
448_I	463_V	0.920	0.68
159_L	185_L	0.920	0.68
428_E	437_I	0.919	0.68
23_A	96_Q	0.916	0.68
432_D	435_T	0.916	0.68
217_Y	241_Q	0.916	0.68
278_G	286_M	0.912	0.68
179_K	183_T	0.911	0.68
288_E	303_L	0.910	0.68
282_R	365_E	0.904	0.67
39_L	58_E	0.902	0.67
48_I	385_T	0.901	0.67
40_E	65_F	0.899	0.67
222_D	305_L	0.895	0.66
434_Q	437_I	0.890	0.66
117_K	120_E	0.889	0.66
149_I	152_A	0.888	0.66
479_T	490_I	0.884	0.65
242_G	270_N	0.882	0.65
133_I	420_V	0.879	0.65
241_Q	244_P	0.877	0.65
110_A	431_G	0.875	0.65
324_T	378_K	0.874	0.64
155_E	183_T	0.873	0.64
298_V	303_L	0.873	0.64
418_V	463_V	0.872	0.64
345_T	348_R	0.865	0.64
259_T	262_V	0.864	0.64
300_T	303_L	0.863	0.63
469_E	482_W	0.862	0.63
234_V	310_T	0.860	0.63
106_V	115_V	0.859	0.63
192_Q	327_N	0.859	0.63
123_V	501_L	0.859	0.63
218_I	330_I	0.859	0.63
123_V	440_V	0.859	0.63
132_E	470_E	0.857	0.63
173_I	405_V	0.857	0.63
218_I	246_L	0.853	0.63
129_N	420_V	0.849	0.62
520_D	526_G	0.845	0.62
49_T	74_A	0.845	0.62
40_E	520_D	0.845	0.62
305_L	309_S	0.844	0.62
349_A	353_E	0.844	0.62
458_E	463_V	0.842	0.62
55_I	202_M	0.841	0.61
51_D	54_T	0.839	0.61
16_L	99_I	0.839	0.61
113_V	509_A	0.838	0.61
14_A	66_E	0.830	0.60
42_K	523_E	0.827	0.60
222_D	298_V	0.825	0.60
381_A	512_L	0.822	0.60
241_Q	312_I	0.821	0.60
262_V	266_R	0.816	0.59
10_E	13_R	0.812	0.59
39_L	54_T	0.808	0.58
421_Y	445_E	0.802	0.58
523_E	526_G	0.801	0.58
47_L	395_E	0.800	0.58
238_V	245_L	0.800	0.58
418_V	445_E	0.800	0.58
203_V	209_M	0.797	0.57
122_A	437_I	0.792	0.57
61_L	66_E	0.792	0.57
521_K	525_N	0.791	0.57
4_E	14_A	0.790	0.57
319_S	334_A	0.788	0.56
476_N	485_M	0.788	0.56
288_E	346_Q	0.785	0.56
245_L	271_A	0.782	0.56
13_R	16_L	0.782	0.56
36_N	513_T	0.775	0.55
180_G	319_S	0.774	0.55
445_E	458_E	0.774	0.55
217_Y	238_V	0.772	0.55
483_V	487_E	0.771	0.55
73_V	511_F	0.770	0.55
17_R	20_D	0.769	0.55
476_N	481_E	0.766	0.54
526_G	530_G	0.766	0.54
64_A	175_I	0.763	0.54
7_F	181_F	0.760	0.54
431_G	434_Q	0.759	0.54
228_I	232_L	0.758	0.54
299_I	311_Q	0.757	0.53
416_A	420_V	0.757	0.53
300_T	305_L	0.756	0.53
19_V	73_V	0.756	0.53
178_S	228_I	0.754	0.53
449_R	460_S	0.754	0.53
252_V	273_A	0.753	0.53
411_S	415_T	0.752	0.53
6_K	10_E	0.751	0.53
422_N	467_K	0.750	0.53
53_V	56_A	0.748	0.53
503_N	512_L	0.746	0.52
526_G	531_M	0.746	0.52
420_V	444_L	0.744	0.52
291_A	296_G	0.742	0.52
54_T	58_E	0.741	0.52
15_M	99_I	0.741	0.52
437_I	441_L	0.739	0.52
136_P	139_G	0.737	0.52
6_K	517_V	0.736	0.51
147_A	248_I	0.736	0.51
125_V	437_I	0.735	0.51
121_Q	437_I	0.735	0.51
349_A	352_E	0.735	0.51
344_V	367_L	0.734	0.51
28_V	516_A	0.734	0.51
422_N	470_E	0.733	0.51
261_V	402_R	0.732	0.51
133_I	411_S	0.732	0.51
463_V	466_L	0.730	0.51
442_R	445_E	0.727	0.51
64_A	522_P	0.727	0.51
6_K	40_E	0.727	0.51
322_V	331_V	0.727	0.51
98_M	511_F	0.726	0.50
452_A	462_I	0.724	0.50
20_D	23_A	0.723	0.50
296_G	314_Q	0.723	0.50
416_A	494_T	0.723	0.50
2_A	5_I	0.722	0.50
71_K	402_R	0.722	0.50
208_K	491_V	0.716	0.49
181_F	184_E	0.716	0.49
115_V	440_V	0.715	0.49
234_V	238_V	0.713	0.49
180_G	432_D	0.711	0.49
431_G	435_T	0.711	0.49
117_K	433_A	0.708	0.49
288_E	302_D	0.707	0.49
440_V	444_L	0.706	0.48
246_L	253_E	0.706	0.48
25_A	516_A	0.706	0.48
526_G	532_P	0.701	0.48
13_R	387_L	0.700	0.48
429_A	434_Q	0.698	0.48
160_I	377_I	0.696	0.48
159_L	183_T	0.696	0.48
470_E	473_V	0.696	0.48
99_I	222_D	0.695	0.47
499_S	502_Q	0.693	0.47
125_V	427_V	0.693	0.47
213_L	321_V	0.692	0.47
40_E	240_Q	0.691	0.47
274_V	323_V	0.690	0.47
33_K	480_G	0.687	0.47
181_F	382_A	0.686	0.47
415_T	466_L	0.686	0.47
141_E	390_R	0.682	0.46
121_Q	125_V	0.682	0.46
18_G	69_G	0.681	0.46
188_V	398_L	0.680	0.46
324_T	329_T	0.680	0.46
4_E	64_A	0.680	0.46
221_T	250_E	0.679	0.46
98_M	505_A	0.678	0.46
30_L	90_T	0.676	0.46
178_S	181_F	0.675	0.45
216_P	243_K	0.674	0.45
292_V	324_T	0.673	0.45
446_E	449_R	0.671	0.45
438_N	442_R	0.671	0.45
354_T	367_L	0.670	0.45
331_V	515_E	0.670	0.45
57_K	223_K	0.669	0.45
68_M	398_L	0.669	0.45
140_K	161_A	0.668	0.45
426_A	441_L	0.668	0.45
440_V	490_I	0.668	0.45
21_A	62_E	0.668	0.45
143_I	405_V	0.668	0.45
226_T	252_V	0.667	0.45
50_N	202_M	0.667	0.45
440_V	505_A	0.667	0.45
249_A	252_V	0.665	0.44
162_E	166_R	0.664	0.44
525_N	530_G	0.664	0.44
19_V	99_I	0.664	0.44
497_T	516_A	0.664	0.44
462_I	477_A	0.664	0.44
65_F	68_M	0.663	0.44
213_L	244_P	0.663	0.44
341_S	344_V	0.662	0.44
276_A	287_L	0.662	0.44
473_V	482_W	0.661	0.44
131_K	134_S	0.659	0.44
118_G	436_G	0.659	0.44
155_E	162_E	0.658	0.44
12_R	515_E	0.657	0.44
131_K	494_T	0.657	0.44
113_V	116_R	0.657	0.44
55_I	399_N	0.656	0.44
2_A	491_V	0.655	0.44
2_A	521_K	0.655	0.44
15_M	21_A	0.655	0.44
521_K	527_G	0.655	0.44
126_A	425_A	0.653	0.43
244_P	510_M	0.649	0.43
128_E	238_V	0.649	0.43
126_A	441_L	0.647	0.43
424_V	427_V	0.646	0.43
4_E	13_R	0.646	0.43
39_L	59_I	0.645	0.43
67_N	71_K	0.645	0.43
38_V	55_I	0.645	0.43
207_D	388_K	0.644	0.42
175_I	394_I	0.644	0.42
381_A	390_R	0.642	0.42
182_T	202_M	0.641	0.42
410_V	416_A	0.640	0.42
147_A	405_V	0.640	0.42
64_A	523_E	0.640	0.42
246_L	274_V	0.640	0.42
198_A	251_D	0.639	0.42
81_N	499_S	0.637	0.42
124_A	502_Q	0.636	0.42
388_K	395_E	0.635	0.42
238_V	242_G	0.634	0.42
150_S	376_V	0.633	0.41
415_T	473_V	0.633	0.41
346_Q	353_E	0.632	0.41
288_E	300_T	0.631	0.41
291_A	298_V	0.631	0.41
111_N	405_V	0.630	0.41
134_S	334_A	0.630	0.41
179_K	182_T	0.629	0.41
152_A	232_L	0.629	0.41
446_E	450_Q	0.629	0.41
104_K	293_L	0.628	0.41
377_I	517_V	0.628	0.41
527_G	532_P	0.627	0.41
265_L	479_T	0.626	0.41
431_G	437_I	0.625	0.41
231_I	234_V	0.625	0.41
219_L	245_L	0.624	0.41
68_M	71_K	0.624	0.41
178_S	184_E	0.623	0.40
132_E	428_E	0.620	0.40
221_T	231_I	0.619	0.40
421_Y	441_L	0.619	0.40
316_G	408_G	0.618	0.40
376_V	507_V	0.618	0.40
110_A	517_V	0.618	0.40
41_K	47_L	0.617	0.40
215_N	319_S	0.617	0.40
83_V	499_S	0.616	0.40
49_T	55_I	0.615	0.40
143_I	164_M	0.615	0.40
38_V	511_F	0.614	0.40
42_K	507_V	0.614	0.40
420_V	423_K	0.614	0.40
433_A	437_I	0.613	0.40
222_D	300_T	0.613	0.40
417_L	421_Y	0.612	0.39
136_P	142_S	0.611	0.39
50_N	99_I	0.611	0.39
159_L	443_A	0.611	0.39
479_T	483_V	0.610	0.39
237_Q	312_I	0.610	0.39
284_K	302_D	0.609	0.39
15_M	517_V	0.607	0.39
93_V	446_E	0.607	0.39
419_N	469_E	0.606	0.39
125_V	129_N	0.606	0.39
246_L	321_V	0.605	0.39
425_A	438_N	0.605	0.39
6_K	9_E	0.605	0.39
389_E	392_L	0.605	0.39
433_A	446_E	0.602	0.39
229_Q	281_D	0.602	0.39
143_I	406_E	0.600	0.38
205_D	210_E	0.598	0.38
244_P	323_V	0.598	0.38
50_N	152_A	0.595	0.38
73_V	76_V	0.595	0.38
389_E	420_V	0.595	0.38
21_A	470_E	0.594	0.38
177_E	387_L	0.594	0.38
39_L	258_A	0.594	0.38
81_N	147_A	0.593	0.38
99_I	437_I	0.593	0.38
70_A	91_A	0.592	0.38
152_A	239_V	0.592	0.38
151_A	157_G	0.591	0.37
366_R	408_G	0.590	0.37
185_L	246_L	0.589	0.37
244_P	272_V	0.589	0.37
212_V	322_V	0.589	0.37
525_N	528_G	0.589	0.37
104_K	108_A	0.588	0.37
392_L	420_V	0.588	0.37
424_V	468_N	0.587	0.37
289_D	408_G	0.585	0.37
212_V	271_A	0.585	0.37
6_K	98_M	0.584	0.37
176_E	282_R	0.584	0.37
383_T	507_V	0.584	0.37
105_N	108_A	0.583	0.37
222_D	358_F	0.583	0.37
114_G	432_D	0.582	0.37
16_L	511_F	0.581	0.37
164_M	401_T	0.580	0.36
126_A	423_K	0.579	0.36
98_M	439_I	0.579	0.36
73_V	84_A	0.578	0.36
289_D	366_R	0.578	0.36
72_L	387_L	0.577	0.36
415_T	448_I	0.576	0.36
123_V	127_I	0.575	0.36
49_T	89_T	0.574	0.36
440_V	508_A	0.573	0.36
7_F	17_R	0.573	0.36
140_K	182_T	0.573	0.36
8_S	62_E	0.573	0.36
118_G	489_G	0.572	0.36
419_N	422_N	0.572	0.36
164_M	398_L	0.572	0.36
139_G	490_I	0.572	0.36
155_E	462_I	0.571	0.36
106_V	478_A	0.570	0.36
419_N	473_V	0.570	0.36
309_S	323_V	0.568	0.35
133_I	416_A	0.568	0.35
322_V	490_I	0.568	0.35
220_I	324_T	0.567	0.35
159_L	214_D	0.566	0.35
217_Y	312_I	0.566	0.35
126_A	129_N	0.566	0.35
255_E	259_T	0.565	0.35
115_V	424_V	0.564	0.35
130_L	445_E	0.564	0.35
22_L	91_A	0.564	0.35
418_V	510_M	0.564	0.35
304_G	307_L	0.563	0.35
33_K	59_I	0.563	0.35
282_R	361_E	0.562	0.35
8_S	511_F	0.562	0.35
336_E	434_Q	0.562	0.35
342_A	354_T	0.561	0.35
336_E	341_S	0.561	0.35
246_L	348_R	0.560	0.35
148_A	175_I	0.560	0.35
105_N	512_L	0.558	0.35
65_F	458_E	0.558	0.35
170_D	231_I	0.557	0.34
262_V	384_E	0.556	0.34
208_K	228_I	0.555	0.34
429_A	433_A	0.554	0.34
465_R	481_E	0.554	0.34
13_R	17_R	0.554	0.34
178_S	207_D	0.553	0.34
442_R	449_R	0.553	0.34
149_I	490_I	0.553	0.34
167_V	171_G	0.553	0.34
296_G	339_K	0.552	0.34
47_L	238_V	0.551	0.34
235_L	263_N	0.551	0.34
415_T	475_F	0.550	0.34
201_Y	325_K	0.549	0.34
57_K	201_Y	0.549	0.34
89_T	396_D	0.549	0.34
181_F	378_K	0.548	0.34
298_V	305_L	0.547	0.34
100_R	502_Q	0.547	0.34
297_E	305_L	0.547	0.34
62_E	66_E	0.546	0.33
225_I	231_I	0.546	0.33
76_V	458_E	0.545	0.33
218_I	321_V	0.545	0.33
165_E	516_A	0.545	0.33
186_E	527_G	0.545	0.33
92_T	495_K	0.545	0.33
338_D	453_H	0.544	0.33
21_A	170_D	0.544	0.33
148_A	322_V	0.543	0.33
54_T	214_D	0.543	0.33
288_E	297_E	0.543	0.33
6_K	521_K	0.542	0.33
174_T	376_V	0.541	0.33
93_V	97_A	0.541	0.33
169_N	395_E	0.541	0.33
133_I	471_I	0.541	0.33
227_N	430_E	0.541	0.33
97_A	446_E	0.540	0.33
99_I	510_M	0.540	0.33
68_M	180_G	0.539	0.33
57_K	78_S	0.538	0.33
231_I	312_I	0.538	0.33
298_V	310_T	0.538	0.33
452_A	455_A	0.537	0.33
459_G	463_V	0.537	0.33
15_M	319_S	0.537	0.33
129_N	422_N	0.537	0.33
71_K	517_V	0.537	0.33
81_N	149_I	0.536	0.33
54_T	459_G	0.536	0.33
340_I	355_T	0.536	0.33
403_A	407_E	0.536	0.33
399_N	509_A	0.536	0.33
448_I	482_W	0.536	0.33
145_Q	185_L	0.535	0.33
176_E	304_G	0.535	0.33
144_A	154_E	0.535	0.33
433_A	483_V	0.534	0.32
230_E	268_T	0.534	0.32
474_G	485_M	0.534	0.32
107_T	466_L	0.533	0.32
99_I	272_V	0.533	0.32
231_I	269_F	0.533	0.32
140_K	159_L	0.533	0.32
525_N	529_A	0.532	0.32
332_E	335_G	0.532	0.32
114_G	195_R	0.532	0.32
139_G	420_V	0.532	0.32
262_V	300_T	0.532	0.32
80_T	409_I	0.532	0.32
168_G	417_L	0.532	0.32
76_V	91_A	0.531	0.32
470_E	487_E	0.531	0.32
47_L	81_N	0.531	0.32
445_E	460_S	0.530	0.32
228_I	348_R	0.530	0.32
449_R	453_H	0.530	0.32
281_D	284_K	0.530	0.32
460_S	464_E	0.530	0.32
43_F	111_N	0.529	0.32
192_Q	203_V	0.529	0.32
234_V	302_D	0.529	0.32
252_V	443_A	0.529	0.32
55_I	105_N	0.528	0.32
162_E	347_I	0.528	0.32
56_A	88_T	0.528	0.32
132_E	336_E	0.527	0.32
15_M	68_M	0.527	0.32
258_A	363_L	0.527	0.32
137_I	155_E	0.527	0.32
69_G	474_G	0.526	0.32
8_S	103_L	0.526	0.32
430_E	434_Q	0.526	0.32
283_R	359_D	0.525	0.32
183_T	390_R	0.525	0.32
481_E	487_E	0.524	0.32
277_P	380_G	0.524	0.32
33_K	64_A	0.524	0.32
446_E	453_H	0.524	0.32
191_M	369_K	0.523	0.31
204_T	264_K	0.523	0.31
96_Q	116_R	0.522	0.31
121_Q	214_D	0.522	0.31
36_N	152_A	0.522	0.31
347_I	363_L	0.522	0.31
55_I	59_I	0.521	0.31
171_G	447_P	0.520	0.31
333_G	336_E	0.520	0.31
110_A	137_I	0.519	0.31
55_I	99_I	0.519	0.31
72_L	507_V	0.519	0.31
159_L	377_I	0.518	0.31
216_P	317_R	0.518	0.31
38_V	324_T	0.517	0.31
24_D	28_V	0.517	0.31
200_P	390_R	0.517	0.31
387_L	390_R	0.516	0.31
121_Q	484_N	0.516	0.31
133_I	419_N	0.515	0.31
200_P	258_A	0.515	0.31
336_E	443_A	0.515	0.31
410_V	494_T	0.514	0.31
166_R	187_V	0.514	0.31
228_I	231_I	0.514	0.31
4_E	522_P	0.514	0.31
162_E	342_A	0.513	0.31
124_A	433_A	0.513	0.31
472_G	486_I	0.512	0.31
278_G	281_D	0.512	0.31
76_V	96_Q	0.512	0.31
183_T	187_V	0.511	0.30
84_A	178_S	0.511	0.30
163_A	323_V	0.510	0.30
50_N	389_E	0.510	0.30
14_A	237_Q	0.509	0.30
114_G	518_V	0.509	0.30
40_E	64_A	0.509	0.30
6_K	519_A	0.509	0.30
351_V	364_Q	0.509	0.30
185_L	192_Q	0.508	0.30
313_A	339_K	0.508	0.30
15_M	208_K	0.507	0.30
472_G	497_T	0.507	0.30
260_L	271_A	0.507	0.30
21_A	218_I	0.507	0.30
207_D	349_A	0.507	0.30
321_V	528_G	0.506	0.30
37_V	516_A	0.506	0.30
52_G	56_A	0.504	0.30
344_V	422_N	0.504	0.30
59_I	518_V	0.504	0.30
56_A	389_E	0.503	0.30
63_D	432_D	0.503	0.30
239_V	268_T	0.503	0.30
232_L	239_V	0.503	0.30
194_D	359_D	0.503	0.30
104_K	107_T	0.503	0.30
212_V	438_N	0.502	0.30
265_L	409_I	0.502	0.30
391_K	451_I	0.502	0.30
143_I	173_I	0.502	0.30
16_L	159_L	0.502	0.30
301_E	309_S	0.502	0.30
146_V	400_S	0.502	0.30
448_I	464_E	0.502	0.30
79_K	83_V	0.501	0.30
152_A	183_T	0.501	0.30
236_E	240_Q	0.500	0.30
522_P	527_G	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kp8A	5	0.9614	100	0.165	Contact Map
1iokA	5	0.8805	100	0.169	Contact Map
3rtkA	2	0.8254	100	0.174	Contact Map
1we3A	5	0.9614	100	0.184	Contact Map
4pj1A	6	0.9596	100	0.213	Contact Map
3ruvA	6	0.8401	100	0.337	Contact Map
1q3qA	4	0.8419	100	0.342	Contact Map
1a6dA	2	0.8309	100	0.35	Contact Map
3p9dC	1	0.8382	100	0.353	Contact Map
3j1bA	4	0.8382	100	0.358	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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