GREMLIN Database
SP5G - Putative septation protein SpoVG
UniProt: P28015 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 97 (88)
Sequences: 530 (314)
Seq/√Len: 33.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
79_E82_R3.9841.00
70_G74_D3.4801.00
28_E71_K2.6191.00
29_F61_T2.2430.99
68_T72_I2.0100.98
25_L31_V2.0060.98
19_A36_V1.9870.98
9_R32_H1.9120.97
2_E71_K1.8950.97
28_E68_T1.7950.96
83_L86_T1.7910.96
74_D78_N1.7300.95
8_L84_G1.6550.94
2_E27_H1.6540.94
79_E83_L1.6130.93
13_T57_F1.5520.91
78_N82_R1.5020.90
32_H46_A1.4630.89
32_H62_H1.4500.88
7_R30_V1.4300.87
42_G73_Q1.4110.87
8_L19_A1.3980.86
34_I45_V1.3440.84
33_D58_R1.3430.84
17_M22_S1.3380.84
65_N68_T1.3310.83
33_D68_T1.3260.83
15_G21_A1.3260.83
45_V68_T1.2870.81
6_V72_I1.2870.81
7_R24_T1.2230.78
3_V25_L1.2140.77
24_T30_V1.1960.76
85_D88_A1.1820.75
23_I75_A1.1710.75
9_R46_A1.1460.73
46_A59_D1.1410.73
5_D15_G1.1260.72
37_I46_A1.1220.71
56_E73_Q1.1210.71
25_L75_A1.0980.70
25_L68_T1.0980.70
67_S71_K1.0700.68
2_E77_L1.0680.68
70_G73_Q1.0510.66
74_D81_H1.0380.65
29_F42_G1.0350.65
78_N81_H1.0330.65
71_K75_A1.0210.64
5_D9_R1.0080.63
61_T65_N0.9930.62
24_T32_H0.9650.60
64_I73_Q0.9640.59
8_L21_A0.9590.59
67_S70_G0.9540.59
17_M53_P0.9130.55
20_I68_T0.9040.55
30_V64_I0.8990.54
34_I76_V0.8870.53
16_R46_A0.8690.52
32_H64_I0.8670.51
23_I72_I0.8640.51
37_I69_R0.8550.50
19_A24_T0.8490.50
18_R38_D0.8180.47
25_L40_N0.8180.47
75_A79_E0.7950.45
66_S70_G0.7830.44
25_L30_V0.7580.42
6_V75_A0.7530.42
17_M54_D0.7530.42
78_N84_G0.7520.42
13_T45_V0.7520.42
46_A61_T0.7420.41
41_N53_P0.7390.41
22_S53_P0.7350.40
20_I32_H0.7260.40
39_G44_F0.7230.40
9_R64_I0.7230.40
20_I34_I0.7130.39
45_V79_E0.7110.39
15_G76_V0.7110.39
13_T25_L0.7050.38
52_T57_F0.7010.38
8_L85_D0.7010.38
9_R17_M0.6970.37
62_H69_R0.6940.37
41_N78_N0.6930.37
22_S33_D0.6930.37
18_R34_I0.6860.37
34_I57_F0.6790.36
33_D50_K0.6780.36
5_D35_R0.6640.35
20_I58_R0.6600.35
26_D50_K0.6560.34
41_N75_A0.6550.34
28_E67_S0.6550.34
25_L72_I0.6540.34
45_V65_N0.6510.34
31_V61_T0.6480.34
30_V73_Q0.6460.34
8_L83_L0.6460.34
82_R86_T0.6330.33
16_R39_G0.6330.33
9_R33_D0.6280.32
33_D64_I0.6260.32
3_V41_N0.6110.31
78_N86_T0.6080.31
17_M20_I0.6050.31
38_D42_G0.5980.30
35_R40_N0.5940.30
81_H85_D0.5930.30
16_R35_R0.5820.29
7_R72_I0.5750.28
37_I73_Q0.5700.28
33_D73_Q0.5660.28
21_A84_G0.5640.28
71_K74_D0.5630.28
2_E82_R0.5630.28
16_R73_Q0.5540.27
2_E16_R0.5530.27
37_I61_T0.5470.27
65_N73_Q0.5450.26
21_A73_Q0.5400.26
27_H31_V0.5270.25
40_N84_G0.5240.25
34_I77_L0.5190.25
22_S58_R0.5180.25
77_L83_L0.5100.24
77_L85_D0.5100.24
43_L81_H0.5030.24
1_M4_T0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ia9A 2 1 100 0.088 Contact Map
2i9zA 2 0.8969 100 0.123 Contact Map
2i9xA 2 0.866 100 0.136 Contact Map
1ez4A 4 0.9278 13.6 0.929 Contact Map
7mdhA 3 0.9794 13.2 0.929 Contact Map
1ybxA 2 0.7216 12.1 0.93 Contact Map
3d0oA 4 0.866 10.7 0.932 Contact Map
4m1qA 4 0.8763 10.1 0.933 Contact Map
3ju0A 1 0.7732 9.4 0.934 Contact Map
1a5zA 3 0.9072 8.9 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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