DPPC - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DPPC - Dipeptide transport system permease protein DppC

UniProt:	P26904	Sequences: MNLPVQTDERQPEQHNQVPDEWFVLNQEKNREADSVKRPSLSYTQDAWRRLKKNKLAMAGLFILLFLFVMAVIGPFLSPHSVVRQSLTEQNLPPSADHWFGTDELGRDVFTRTWYGARISLFVGVMAALIDFLIGVIYGGVAGYKGGRIDSIMMRIIEVLYGLPYLLVVILLMVLMGPGLGTIIVALTVTGWVGMARIVRGQVLQIKNYEYVLASKTFGAKTFRIIRKNLLPNTMGAIIVQMTLTVPAAIFAESFLSFLGLGIQAPFASWGVMANDGLPTILSGHWWRLFFPAFFISLTMYAFNVLGDGLQDALDPKLRR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	320 (252)
Sequences:	28207 (17586)
Seq/√Len:	1107.8

ECOLI - DPPC YEJE SAPC GSID DDPC OPPC NIKC YEJB DDPB DPPB NIKB GSIC SAPB OPPB
BACSU - DPPC APPC OPPC OPPB APPB DPPB
HALSA - Q9HMW2 Q9HMI1 Q9HMX1 Q9HMI2 Q9HMX0 Q9HMW3
SULSO - Q97UH2 Q97YP2 Q97UG3 Q97VK7 Q97YP9 Q97VF6 Q97VF8 Q97VK6 Q97UH1 Q97YP1 Q97YQ0 Q97UG4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
203_V	230_L	2.809	1.00
150_D	200_R	2.774	1.00
216_K	222_T	2.489	1.00
206_I	211_Y	2.452	1.00
224_R	228_K	2.425	1.00
220_A	224_R	2.415	1.00
138_Y	153_M	2.392	1.00
126_M	184_I	2.355	1.00
206_I	209_Y	2.350	1.00
130_I	188_T	2.306	1.00
119_I	258_F	2.294	1.00
221_K	224_R	2.262	1.00
223_F	227_R	2.229	1.00
86_S	89_E	2.228	1.00
210_E	213_L	2.125	1.00
272_V	276_D	2.118	1.00
212_V	230_L	2.062	1.00
212_V	225_I	2.007	1.00
112_R	273_M	1.994	1.00
243_T	307_G	1.993	1.00
140_G	203_V	1.983	1.00
96_A	99_W	1.957	1.00
145_K	222_T	1.939	1.00
141_V	145_K	1.882	1.00
145_K	149_I	1.871	1.00
108_D	111_T	1.863	1.00
133_L	137_I	1.845	1.00
195_M	245_T	1.843	1.00
81_S	84_R	1.784	1.00
103_D	107_R	1.779	1.00
148_R	152_I	1.778	1.00
211_Y	233_N	1.768	1.00
143_G	203_V	1.753	1.00
144_Y	222_T	1.741	1.00
71_A	117_A	1.714	1.00
206_I	234_T	1.713	1.00
65_L	69_V	1.706	1.00
100_F	291_F	1.662	1.00
134_I	137_I	1.662	1.00
110_F	114_W	1.645	1.00
134_I	192_W	1.644	1.00
98_H	108_D	1.631	1.00
105_L	112_R	1.611	1.00
207_K	230_L	1.606	1.00
149_I	153_M	1.603	1.00
109_V	291_F	1.601	1.00
141_V	149_I	1.580	1.00
131_D	191_G	1.579	1.00
184_I	188_T	1.563	1.00
122_F	126_M	1.562	1.00
132_F	242_M	1.548	1.00
202_Q	205_Q	1.545	1.00
144_Y	226_I	1.539	1.00
153_M	196_A	1.522	1.00
57_A	309_G	1.505	1.00
157_I	196_A	1.504	1.00
115_Y	118_R	1.503	1.00
104_E	276_D	1.494	1.00
277_G	288_R	1.492	1.00
107_R	111_T	1.445	1.00
135_G	195_M	1.425	1.00
274_A	292_P	1.418	1.00
128_A	242_M	1.414	1.00
205_Q	209_Y	1.412	1.00
73_I	76_F	1.399	1.00
139_G	143_G	1.395	1.00
60_G	302_A	1.383	1.00
155_R	158_E	1.378	1.00
200_R	204_L	1.375	1.00
214_A	218_F	1.361	1.00
143_G	207_K	1.338	1.00
89_E	92_L	1.337	1.00
139_G	199_V	1.327	1.00
135_G	199_V	1.326	1.00
167_L	171_L	1.322	1.00
67_L	297_S	1.301	1.00
240_V	311_Q	1.301	1.00
206_I	212_V	1.287	1.00
58_M	62_F	1.278	1.00
119_I	122_F	1.276	1.00
100_F	110_F	1.274	1.00
138_Y	196_A	1.268	1.00
206_I	230_L	1.267	1.00
140_G	226_I	1.266	1.00
311_Q	315_D	1.263	1.00
148_R	151_S	1.258	1.00
188_T	192_W	1.257	1.00
181_G	185_V	1.253	1.00
198_I	241_Q	1.246	1.00
113_T	295_F	1.242	1.00
142_A	153_M	1.241	1.00
310_L	313_A	1.240	1.00
69_V	73_I	1.235	1.00
286_W	290_F	1.230	1.00
146_G	207_K	1.217	1.00
239_I	314_L	1.211	1.00
172_L	186_A	1.210	1.00
55_K	58_M	1.190	1.00
215_S	229_N	1.186	1.00
123_V	253_E	1.154	1.00
140_G	231_L	1.154	1.00
107_R	112_R	1.151	1.00
203_V	234_T	1.147	1.00
95_S	100_F	1.146	1.00
215_S	225_I	1.129	1.00
160_L	193_V	1.126	1.00
64_L	298_L	1.107	1.00
309_G	313_A	1.107	1.00
151_S	155_R	1.103	1.00
107_R	115_Y	1.098	1.00
215_S	220_A	1.096	1.00
199_V	238_I	1.091	1.00
213_L	216_K	1.084	1.00
186_A	190_T	1.080	1.00
199_V	203_V	1.073	1.00
100_F	113_T	1.072	1.00
292_P	296_I	1.065	1.00
136_V	199_V	1.060	1.00
179_G	182_T	1.055	1.00
202_Q	206_I	1.054	1.00
218_F	229_N	1.050	1.00
74_G	115_Y	1.049	1.00
67_L	299_T	1.046	1.00
104_E	280_T	1.043	1.00
224_R	227_R	1.042	1.00
137_I	140_G	1.039	1.00
60_G	309_G	1.032	1.00
277_G	289_L	1.027	1.00
64_L	302_A	1.026	1.00
181_G	184_I	1.025	1.00
273_M	288_R	1.024	1.00
169_V	186_A	1.024	1.00
163_L	168_V	1.023	1.00
150_D	154_M	1.022	1.00
109_V	273_M	1.020	1.00
109_V	288_R	1.017	1.00
192_W	196_A	1.017	1.00
246_V	303_F	1.016	1.00
156_I	160_L	1.014	1.00
78_S	111_T	1.008	1.00
118_R	122_F	0.991	1.00
127_A	188_T	0.990	1.00
102_T	108_D	0.988	1.00
154_M	196_A	0.988	1.00
215_S	218_F	0.981	1.00
62_F	66_F	0.980	1.00
122_F	180_L	0.979	1.00
80_H	97_D	0.979	1.00
150_D	204_L	0.978	1.00
199_V	234_T	0.976	1.00
63_I	302_A	0.975	1.00
62_F	65_L	0.972	1.00
216_K	225_I	0.971	1.00
111_T	115_Y	0.966	1.00
112_R	288_R	0.963	1.00
59_A	62_F	0.955	1.00
152_I	156_I	0.952	1.00
236_G	311_Q	0.949	1.00
127_A	187_L	0.944	1.00
275_N	279_P	0.941	1.00
287_W	291_F	0.940	1.00
60_G	305_V	0.939	1.00
61_L	65_L	0.939	1.00
146_G	208_N	0.938	1.00
60_G	301_Y	0.938	1.00
127_A	131_D	0.938	1.00
147_G	150_D	0.937	1.00
113_T	291_F	0.933	1.00
95_S	98_H	0.931	1.00
149_I	152_I	0.929	1.00
116_G	273_M	0.929	1.00
176_M	182_T	0.926	1.00
291_F	294_F	0.923	1.00
122_F	125_V	0.913	1.00
302_A	306_L	0.912	1.00
220_A	225_I	0.910	1.00
139_G	203_V	0.906	1.00
165_Y	252_A	0.906	1.00
66_F	70_M	0.900	1.00
151_S	154_M	0.898	1.00
63_I	298_L	0.893	1.00
92_L	95_S	0.890	1.00
222_T	225_I	0.889	1.00
98_H	102_T	0.884	1.00
88_T	92_L	0.878	1.00
132_F	136_V	0.875	1.00
147_G	151_S	0.871	1.00
136_V	238_I	0.867	1.00
157_I	193_V	0.859	1.00
95_S	99_W	0.856	1.00
303_F	307_G	0.855	1.00
70_M	114_W	0.852	1.00
187_L	252_A	0.848	1.00
234_T	237_A	0.848	1.00
239_I	307_G	0.846	1.00
61_L	306_L	0.844	1.00
80_H	98_H	0.843	1.00
201_G	204_L	0.841	1.00
133_L	136_V	0.837	1.00
117_A	299_T	0.837	1.00
178_P	182_T	0.834	1.00
111_T	114_W	0.828	1.00
112_R	115_Y	0.826	1.00
102_T	106_G	0.822	1.00
57_A	305_V	0.818	1.00
177_G	182_T	0.815	1.00
180_L	184_I	0.812	1.00
165_Y	169_V	0.812	1.00
222_T	226_I	0.811	1.00
241_Q	245_T	0.810	1.00
185_V	188_T	0.808	1.00
203_V	207_K	0.807	1.00
143_G	204_L	0.802	1.00
114_W	118_R	0.800	1.00
290_F	294_F	0.800	1.00
80_H	111_T	0.800	1.00
227_R	230_L	0.798	1.00
213_L	217_T	0.797	1.00
132_F	137_I	0.794	1.00
276_D	279_P	0.789	1.00
209_Y	213_L	0.786	1.00
76_F	286_W	0.786	1.00
91_N	94_P	0.784	1.00
172_L	182_T	0.775	1.00
57_A	61_L	0.774	1.00
182_T	185_V	0.771	1.00
120_S	124_G	0.768	1.00
73_I	77_L	0.768	1.00
138_Y	192_W	0.766	1.00
206_I	233_N	0.764	1.00
126_M	258_F	0.763	1.00
273_M	292_P	0.758	1.00
142_A	150_D	0.758	1.00
125_V	129_L	0.757	1.00
127_A	249_A	0.756	1.00
132_F	195_M	0.754	1.00
220_A	229_N	0.750	1.00
72_V	76_F	0.750	1.00
137_I	141_V	0.748	1.00
275_N	278_L	0.748	1.00
103_D	285_H	0.746	1.00
296_I	300_M	0.738	1.00
126_M	129_L	0.737	1.00
99_W	110_F	0.736	1.00
130_I	184_I	0.736	1.00
70_M	117_A	0.733	1.00
312_D	318_L	0.729	1.00
202_Q	237_A	0.723	1.00
199_V	202_Q	0.721	1.00
79_P	111_T	0.720	1.00
291_F	295_F	0.719	1.00
68_F	294_F	0.716	1.00
59_A	63_I	0.715	1.00
276_D	280_T	0.714	1.00
223_F	226_I	0.712	1.00
161_Y	193_V	0.711	1.00
94_P	287_W	0.710	1.00
225_I	230_L	0.709	1.00
114_W	117_A	0.704	1.00
243_T	303_F	0.698	1.00
56_L	60_G	0.694	1.00
306_L	310_L	0.694	1.00
90_Q	94_P	0.693	1.00
89_E	98_H	0.692	1.00
202_Q	234_T	0.690	1.00
134_I	188_T	0.690	1.00
88_T	91_N	0.687	1.00
135_G	139_G	0.682	1.00
95_S	294_F	0.680	1.00
298_L	302_A	0.680	1.00
64_L	303_F	0.677	1.00
79_P	110_F	0.675	1.00
67_L	298_L	0.674	1.00
131_D	188_T	0.673	1.00
311_Q	318_L	0.673	1.00
251_F	254_S	0.666	1.00
55_K	59_A	0.661	1.00
154_M	157_I	0.661	1.00
93_P	287_W	0.659	1.00
60_G	63_I	0.656	1.00
113_T	292_P	0.653	1.00
253_E	257_S	0.649	1.00
142_A	154_M	0.648	1.00
191_G	194_G	0.646	1.00
99_W	108_D	0.645	1.00
134_I	138_Y	0.644	1.00
289_L	293_A	0.643	1.00
300_M	304_N	0.641	1.00
290_F	293_A	0.640	1.00
128_A	245_T	0.638	1.00
190_T	193_V	0.637	1.00
87_L	90_Q	0.634	1.00
86_S	90_Q	0.631	1.00
63_I	67_L	0.626	1.00
145_K	226_I	0.625	1.00
183_I	253_E	0.624	1.00
144_Y	207_K	0.623	1.00
80_H	284_G	0.621	1.00
91_N	285_H	0.620	1.00
58_M	61_L	0.617	1.00
128_A	246_V	0.617	1.00
165_Y	168_V	0.617	1.00
204_L	207_K	0.614	1.00
220_A	223_F	0.613	1.00
153_M	157_I	0.609	1.00
195_M	199_V	0.607	1.00
178_P	181_G	0.606	1.00
121_L	125_V	0.605	1.00
252_A	255_F	0.604	1.00
152_I	155_R	0.599	1.00
251_F	255_F	0.599	1.00
249_A	252_A	0.599	1.00
75_P	118_R	0.598	1.00
144_Y	227_R	0.597	1.00
157_I	192_W	0.597	1.00
129_L	133_L	0.596	1.00
254_S	272_V	0.590	1.00
146_G	204_L	0.588	1.00
195_M	241_Q	0.587	1.00
168_V	190_T	0.586	1.00
132_F	238_I	0.586	1.00
274_A	296_I	0.583	1.00
78_S	115_Y	0.580	1.00
194_G	245_T	0.577	1.00
146_G	150_D	0.576	1.00
70_M	74_G	0.574	1.00
71_A	293_A	0.574	1.00
155_R	159_V	0.573	1.00
160_L	192_W	0.573	1.00
182_T	186_A	0.572	1.00
117_A	121_L	0.571	1.00
171_L	175_L	0.569	1.00
124_G	249_A	0.568	1.00
273_M	276_D	0.568	1.00
254_S	275_N	0.567	1.00
126_M	181_G	0.564	1.00
240_V	243_T	0.562	1.00
142_A	200_R	0.557	1.00
189_V	192_W	0.557	1.00
227_R	232_P	0.555	1.00
118_R	121_L	0.552	1.00
250_I	254_S	0.548	1.00
305_V	309_G	0.545	1.00
191_G	245_T	0.545	1.00
135_G	196_A	0.543	1.00
143_G	150_D	0.542	1.00
158_E	161_Y	0.541	1.00
273_M	277_G	0.537	1.00
308_D	311_Q	0.536	1.00
75_P	115_Y	0.536	1.00
173_M	177_G	0.535	1.00
165_Y	189_V	0.535	1.00
123_V	183_I	0.534	1.00
74_G	77_L	0.532	1.00
91_N	288_R	0.528	1.00
193_V	196_A	0.528	1.00
212_V	216_K	0.527	1.00
198_I	202_Q	0.526	1.00
154_M	158_E	0.525	1.00
221_K	225_I	0.524	1.00
92_L	102_T	0.523	1.00
128_A	132_F	0.522	1.00
254_S	276_D	0.520	1.00
123_V	184_I	0.520	1.00
138_Y	141_V	0.520	1.00
185_V	189_V	0.519	1.00
67_L	71_A	0.519	1.00
287_W	290_F	0.515	1.00
68_F	72_V	0.514	1.00
56_L	305_V	0.513	1.00
112_R	276_D	0.507	1.00
112_R	116_G	0.507	1.00
194_G	241_Q	0.506	1.00
84_R	88_T	0.503	1.00
129_L	132_F	0.501	1.00
167_L	170_I	0.501	1.00
116_G	272_V	0.500	1.00
247_P	300_M	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4tquM	1	0.7906	99.9	0.644	Contact Map
3d31C	2	0.7219	99.9	0.658	Contact Map
3tuiA	2	0.6344	99.9	0.67	Contact Map
3rlfF	1	0.9281	99.9	0.67	Contact Map
2onkC	2	0.7406	99.9	0.675	Contact Map
4tquN	1	0.8094	99.9	0.695	Contact Map
3rlfG	1	0.7906	99.9	0.695	Contact Map
4ymuD	2	0.6438	99.9	0.701	Contact Map
3j9pD	4	0.7688	73.4	0.94	Contact Map
2kogA	1	0.2437	27.5	0.955	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0093 seconds.