ASPA - BACSU - GREMLIN Contacts

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ASPA - Aspartate ammonia-lyase

UniProt:	P26899	Sequences: MLNGQKEYRVEKDFLGEKQIEADVYYGIQTLRASENFPITGYKIHEEMINALAIVKKAAALANMDVKRLYEGIGQAIVQAADEILEGKWHDQFIVDPIQGGAGTSMNMNANEVIGNRALEIMGHKKGDYIHLSPNTHVNMSQSTNDVFPTAIHISTLKLLEKLLKTMEDMHSVFKQKAQEFDSVIKMGRTHLQDAVPIRLGQEFEAYSRVLERDIKRIKQSRQHLYEVNMGATAVGTGLNADPEYIKQVVKHLADISGLPLVGADHLVDATQNTDAYTEVSASLKVCMMNMSKIANDLRLMASGPRAGLAEISLPARQPGSSIMPGKVNPVMAELINQIAFQVIGNDNTICLASEAGQLELNVMEPVLVFNLLQSISIMNNGFRSFTDNCLKGIEANEKRMKQYVEKSAGVITAVNPHLGYEAAARIAREAIMTGQSVRDLCLQHDVLTEEELDIILNPYEMTKPGIAGKELLEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	475 (403)
Sequences:	10905 (5739)
Seq/√Len:	285.9

ECOLI - FUMC ASPA ARLY PUR8
BACSU - ASPA FUMC ARLY PUR8
HALSA - FUMC ARLY Q9HS42
SULSO - FUMC Q980P8 ARLY

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
64_M	74_G	3.877	1.00
73_I	137_H	3.466	1.00
65_D	252_H	3.324	1.00
57_K	82_D	3.307	1.00
61_L	78_V	3.237	1.00
400_R	403_Q	3.206	1.00
51_A	158_K	2.877	1.00
168_E	215_I	2.840	1.00
61_L	256_I	2.744	1.00
288_M	343_V	2.728	1.00
171_H	212_E	2.717	1.00
164_L	219_K	2.620	1.00
402_K	406_E	2.617	1.00
160_L	280_V	2.608	1.00
173_V	392_K	2.607	1.00
47_E	377_S	2.595	1.00
117_R	121_I	2.539	1.00
161_E	222_R	2.517	1.00
449_T	452_E	2.513	1.00
346_N	375_S	2.486	1.00
224_H	279_E	2.482	1.00
200_L	396_A	2.477	1.00
252_H	255_D	2.419	1.00
164_L	215_I	2.390	1.00
339_I	382_G	2.295	1.00
177_K	180_E	2.293	1.00
285_K	347_D	2.257	1.00
70_Y	73_I	2.242	1.00
157_L	226_Y	2.227	1.00
183_S	398_E	2.198	1.00
64_M	71_E	2.192	1.00
226_Y	260_P	2.153	1.00
313_S	395_E	2.070	1.00
168_E	219_K	2.055	1.00
403_Q	407_K	2.038	1.00
166_T	384_R	2.005	1.00
342_Q	371_N	2.005	1.00
171_H	215_I	1.998	1.00
71_E	75_Q	1.966	1.00
176_Q	392_K	1.964	1.00
173_V	387_T	1.951	1.00
436_Q	444_Q	1.946	1.00
176_Q	180_E	1.936	1.00
452_E	455_I	1.924	1.00
252_H	256_I	1.922	1.00
400_R	404_Y	1.907	1.00
173_V	391_L	1.891	1.00
289_M	344_I	1.890	1.00
220_Q	224_H	1.881	1.00
295_A	336_I	1.872	1.00
215_I	219_K	1.859	1.00
415_V	418_H	1.830	1.00
54_I	158_K	1.819	1.00
75_Q	79_Q	1.806	1.00
217_R	279_E	1.792	1.00
83_E	121_I	1.751	1.00
167_M	287_C	1.746	1.00
175_K	212_E	1.740	1.00
402_K	460_Y	1.735	1.00
57_K	78_V	1.733	1.00
228_V	254_A	1.731	1.00
220_Q	223_Q	1.731	1.00
181_F	184_V	1.706	1.00
423_A	426_R	1.704	1.00
387_T	392_K	1.701	1.00
450_E	454_D	1.699	1.00
291_M	336_I	1.688	1.00
171_H	208_S	1.661	1.00
446_D	449_T	1.655	1.00
398_E	402_K	1.652	1.00
439_R	454_D	1.650	1.00
458_N	461_E	1.649	1.00
436_Q	441_L	1.642	1.00
278_T	354_S	1.631	1.00
214_D	290_N	1.627	1.00
61_L	252_H	1.618	1.00
264_A	270_A	1.617	1.00
74_G	78_V	1.610	1.00
227_E	262_V	1.610	1.00
213_R	269_D	1.606	1.00
169_D	387_T	1.575	1.00
230_M	249_V	1.556	1.00
251_K	255_D	1.554	1.00
76_A	122_M	1.542	1.00
443_L	450_E	1.530	1.00
57_K	85_L	1.522	1.00
166_T	380_N	1.520	1.00
232_A	270_A	1.495	1.00
349_T	367_V	1.494	1.00
430_E	445_H	1.475	1.00
177_K	181_F	1.474	1.00
178_A	208_S	1.469	1.00
348_N	352_L	1.438	1.00
62_A	252_H	1.437	1.00
430_E	434_T	1.433	1.00
223_Q	260_P	1.429	1.00
285_K	351_C	1.415	1.00
221_S	283_S	1.407	1.00
159_L	380_N	1.388	1.00
213_R	275_D	1.378	1.00
117_R	120_E	1.378	1.00
333_A	390_C	1.374	1.00
274_T	365_E	1.356	1.00
82_D	86_E	1.346	1.00
281_S	350_I	1.343	1.00
216_K	224_H	1.335	1.00
87_G	121_I	1.327	1.00
50_N	54_I	1.321	1.00
397_N	400_R	1.320	1.00
399_K	403_Q	1.316	1.00
300_L	358_Q	1.311	1.00
171_H	211_L	1.307	1.00
47_E	159_L	1.306	1.00
57_K	61_L	1.303	1.00
295_A	386_F	1.296	1.00
156_T	280_V	1.293	1.00
282_A	286_V	1.288	1.00
451_E	454_D	1.280	1.00
76_A	79_Q	1.275	1.00
204_F	207_Y	1.275	1.00
289_M	354_S	1.267	1.00
52_L	147_V	1.266	1.00
278_T	286_V	1.265	1.00
60_A	69_L	1.258	1.00
164_L	222_R	1.258	1.00
169_D	392_K	1.257	1.00
175_K	179_Q	1.254	1.00
42_Y	374_Q	1.246	1.00
50_N	85_L	1.241	1.00
342_Q	374_Q	1.238	1.00
207_Y	360_E	1.236	1.00
423_A	447_V	1.234	1.00
437_S	440_D	1.231	1.00
173_V	176_Q	1.230	1.00
344_I	352_L	1.228	1.00
110_A	114_I	1.226	1.00
419_L	427_I	1.217	1.00
184_V	398_E	1.214	1.00
311_E	397_N	1.213	1.00
200_L	204_F	1.212	1.00
345_G	349_T	1.212	1.00
167_M	211_L	1.208	1.00
311_E	395_E	1.208	1.00
436_Q	440_D	1.200	1.00
141_S	241_A	1.197	1.00
179_Q	182_D	1.197	1.00
53_A	85_L	1.194	1.00
181_F	398_E	1.176	1.00
53_A	110_A	1.172	1.00
218_I	287_C	1.162	1.00
68_R	140_M	1.161	1.00
53_A	84_I	1.159	1.00
156_T	372_L	1.152	1.00
254_A	260_P	1.149	1.00
166_T	387_T	1.146	1.00
71_E	74_G	1.146	1.00
350_I	372_L	1.145	1.00
83_E	117_R	1.142	1.00
445_H	449_T	1.141	1.00
336_I	382_G	1.139	1.00
194_D	305_P	1.128	1.00
175_K	208_S	1.123	1.00
83_E	88_K	1.123	1.00
200_L	401_M	1.114	1.00
168_E	172_S	1.113	1.00
141_S	242_D	1.106	1.00
182_D	201_G	1.106	1.00
347_D	351_C	1.096	1.00
166_T	169_D	1.094	1.00
164_L	168_E	1.094	1.00
174_F	294_I	1.092	1.00
298_L	333_A	1.086	1.00
250_V	254_A	1.084	1.00
417_P	452_E	1.081	1.00
80_A	83_E	1.081	1.00
186_K	401_M	1.079	1.00
170_M	211_L	1.076	1.00
82_D	85_L	1.074	1.00
157_L	259_L	1.074	1.00
340_A	344_I	1.072	1.00
169_D	384_R	1.071	1.00
159_L	162_K	1.065	1.00
50_N	89_W	1.063	1.00
58_A	256_I	1.060	1.00
209_R	265_D	1.059	1.00
76_A	80_A	1.058	1.00
183_S	201_G	1.055	1.00
277_Y	372_L	1.048	1.00
197_P	405_V	1.048	1.00
439_R	443_L	1.048	1.00
170_M	391_L	1.047	1.00
434_T	441_L	1.042	1.00
162_K	380_N	1.041	1.00
207_Y	294_I	1.040	1.00
216_K	223_Q	1.038	1.00
51_A	154_I	1.035	1.00
55_V	147_V	1.031	1.00
46_E	90_H	1.028	1.00
445_H	448_L	1.026	1.00
150_T	228_V	1.024	1.00
75_Q	78_V	1.023	1.00
283_S	287_C	1.023	1.00
194_D	304_G	1.013	1.00
152_I	369_V	1.012	1.00
182_D	199_R	1.010	1.00
418_H	456_I	1.009	1.00
226_Y	259_L	1.009	1.00
177_K	204_F	1.008	1.00
184_V	401_M	1.008	1.00
160_L	222_R	1.007	1.00
78_V	82_D	1.006	1.00
292_S	337_N	1.004	1.00
177_K	391_L	1.003	1.00
198_I	235_V	0.996	1.00
198_I	268_V	0.994	1.00
79_Q	121_I	0.992	1.00
199_R	463_T	0.992	1.00
65_D	256_I	0.990	1.00
440_D	444_Q	0.988	1.00
50_N	158_K	0.988	1.00
191_H	334_E	0.985	1.00
64_M	75_Q	0.980	1.00
419_L	424_A	0.980	1.00
94_I	119_L	0.978	1.00
157_L	222_R	0.977	1.00
300_L	359_L	0.977	1.00
317_R	389_N	0.974	1.00
415_V	419_L	0.974	1.00
313_S	397_N	0.974	1.00
152_I	277_Y	0.972	1.00
83_E	87_G	0.971	1.00
228_V	253_L	0.970	1.00
54_I	256_I	0.968	1.00
188_G	198_I	0.967	1.00
209_R	213_R	0.965	1.00
291_M	383_F	0.965	1.00
167_M	215_I	0.964	1.00
222_R	226_Y	0.963	1.00
280_V	372_L	0.963	1.00
298_L	394_I	0.958	1.00
185_I	463_T	0.955	1.00
437_S	441_L	0.954	1.00
76_A	134_P	0.946	1.00
220_Q	279_E	0.942	1.00
160_L	218_I	0.942	1.00
46_E	50_N	0.941	1.00
94_I	97_P	0.935	1.00
216_K	220_Q	0.932	1.00
79_Q	83_E	0.927	1.00
54_I	253_L	0.926	1.00
52_L	110_A	0.924	1.00
438_V	441_L	0.924	1.00
108_M	111_N	0.923	1.00
202_Q	267_L	0.923	1.00
189_R	194_D	0.918	1.00
66_V	242_D	0.913	1.00
55_V	150_T	0.909	1.00
312_I	394_I	0.909	1.00
282_A	347_D	0.907	1.00
47_E	158_K	0.899	1.00
171_H	175_K	0.898	1.00
111_N	115_G	0.897	1.00
172_S	176_Q	0.894	1.00
281_S	347_D	0.893	1.00
262_V	265_D	0.888	1.00
342_Q	370_F	0.887	1.00
174_F	204_F	0.886	1.00
70_Y	137_H	0.886	1.00
54_I	85_L	0.885	1.00
52_L	55_V	0.883	1.00
406_E	439_R	0.879	1.00
62_A	66_V	0.878	1.00
430_E	444_Q	0.877	1.00
72_G	75_Q	0.874	1.00
180_E	395_E	0.871	1.00
281_S	372_L	0.870	1.00
178_A	205_E	0.869	1.00
405_V	459_P	0.869	1.00
184_V	396_A	0.868	1.00
189_R	305_P	0.868	1.00
62_A	249_V	0.863	1.00
287_C	383_F	0.862	1.00
208_S	212_E	0.861	1.00
451_E	455_I	0.859	1.00
93_F	97_P	0.859	1.00
51_A	155_S	0.855	1.00
430_E	441_L	0.852	1.00
418_H	452_E	0.849	1.00
439_R	450_E	0.848	1.00
268_V	360_E	0.846	1.00
441_L	444_Q	0.845	1.00
203_E	360_E	0.843	1.00
158_K	161_E	0.835	1.00
192_L	300_L	0.835	1.00
133_S	136_T	0.833	1.00
152_I	372_L	0.827	1.00
370_F	374_Q	0.824	1.00
292_S	355_E	0.823	1.00
440_D	450_E	0.820	1.00
452_E	456_I	0.812	0.99
336_I	386_F	0.812	0.99
194_D	408_S	0.811	0.99
119_L	135_N	0.811	0.99
263_G	267_L	0.809	0.99
174_F	208_S	0.805	0.99
174_F	391_L	0.805	0.99
289_M	351_C	0.804	0.99
249_V	253_L	0.803	0.99
273_N	290_N	0.802	0.99
86_E	90_H	0.802	0.99
282_A	351_C	0.800	0.99
173_V	177_K	0.799	0.99
185_I	405_V	0.794	0.99
312_I	393_G	0.791	0.99
64_M	69_L	0.790	0.99
181_F	396_A	0.790	0.99
294_I	386_F	0.789	0.99
83_E	89_W	0.789	0.99
50_N	90_H	0.784	0.99
65_D	71_E	0.783	0.99
341_F	349_T	0.782	0.99
87_G	117_R	0.781	0.99
346_N	374_Q	0.781	0.99
203_E	301_M	0.780	0.99
89_W	117_R	0.779	0.99
279_E	282_A	0.778	0.99
349_T	371_N	0.774	0.99
59_A	142_Q	0.773	0.99
233_T	323_I	0.772	0.99
60_A	74_G	0.771	0.99
192_L	303_S	0.771	0.99
227_E	276_A	0.770	0.99
115_G	118_A	0.766	0.99
213_R	227_E	0.766	0.99
73_I	134_P	0.766	0.99
187_M	307_A	0.761	0.99
180_E	398_E	0.760	0.99
342_Q	346_N	0.758	0.99
72_G	76_A	0.755	0.99
229_N	270_A	0.755	0.99
313_S	393_G	0.753	0.99
426_R	430_E	0.748	0.99
344_I	348_N	0.745	0.99
416_N	419_L	0.745	0.99
226_Y	254_A	0.744	0.99
80_A	122_M	0.744	0.99
167_M	383_F	0.743	0.99
308_G	397_N	0.743	0.99
183_S	460_Y	0.741	0.99
301_M	359_L	0.740	0.99
453_L	457_L	0.739	0.99
186_K	203_E	0.736	0.99
250_V	263_G	0.730	0.99
313_S	316_A	0.729	0.99
57_K	256_I	0.726	0.99
58_A	61_L	0.725	0.99
189_R	304_G	0.724	0.99
275_D	290_N	0.724	0.99
390_C	394_I	0.724	0.99
443_L	454_D	0.722	0.99
160_L	221_S	0.722	0.99
73_I	77_I	0.722	0.99
272_Q	360_E	0.722	0.99
341_F	353_A	0.720	0.99
77_I	134_P	0.720	0.99
69_L	140_M	0.720	0.99
353_A	367_V	0.719	0.99
61_L	65_D	0.719	0.99
269_D	275_D	0.719	0.99
436_Q	442_C	0.719	0.99
448_L	456_I	0.715	0.99
269_D	290_N	0.713	0.99
280_V	284_L	0.711	0.99
295_A	333_A	0.708	0.99
81_A	84_I	0.708	0.99
250_V	253_L	0.707	0.99
44_I	370_F	0.707	0.99
184_V	199_R	0.706	0.99
211_L	383_F	0.706	0.99
48_M	148_F	0.704	0.99
315_P	393_G	0.702	0.99
280_V	377_S	0.700	0.99
87_G	92_Q	0.700	0.99
116_N	120_E	0.699	0.98
85_L	89_W	0.698	0.98
163_L	380_N	0.696	0.98
206_A	293_K	0.694	0.98
277_Y	350_I	0.693	0.98
170_M	387_T	0.693	0.98
294_I	391_L	0.692	0.98
399_K	402_K	0.692	0.98
162_K	166_T	0.690	0.98
176_Q	179_Q	0.690	0.98
65_D	242_D	0.688	0.98
84_I	114_I	0.688	0.98
396_A	401_M	0.688	0.98
163_L	376_I	0.688	0.98
346_N	376_I	0.687	0.98
153_H	276_A	0.686	0.98
217_R	275_D	0.685	0.98
172_S	175_K	0.685	0.98
57_K	74_G	0.682	0.98
210_V	290_N	0.680	0.98
168_E	212_E	0.679	0.98
210_V	273_N	0.679	0.98
342_Q	378_I	0.675	0.98
68_R	242_D	0.675	0.98
134_P	137_H	0.673	0.98
211_L	214_D	0.673	0.98
296_N	337_N	0.669	0.98
419_L	423_A	0.668	0.98
278_T	350_I	0.666	0.98
204_F	401_M	0.666	0.98
253_L	256_I	0.665	0.98
223_Q	226_Y	0.664	0.98
214_D	286_V	0.664	0.98
230_M	253_L	0.663	0.98
60_A	77_I	0.663	0.98
157_L	161_E	0.662	0.98
184_V	402_K	0.661	0.98
287_C	379_M	0.660	0.98
174_F	211_L	0.660	0.98
344_I	351_C	0.654	0.98
181_F	200_L	0.654	0.98
168_E	171_H	0.654	0.98
216_K	219_K	0.653	0.98
73_I	76_A	0.652	0.98
460_Y	464_K	0.651	0.98
383_F	387_T	0.648	0.98
372_L	376_I	0.646	0.97
161_E	259_L	0.646	0.97
157_L	260_P	0.644	0.97
66_V	252_H	0.643	0.97
304_G	308_G	0.642	0.97
169_D	173_V	0.642	0.97
160_L	225_L	0.642	0.97
227_E	264_A	0.642	0.97
155_S	376_I	0.640	0.97
42_Y	370_F	0.640	0.97
187_M	405_V	0.640	0.97
186_K	198_I	0.637	0.97
348_N	351_C	0.636	0.97
249_V	252_H	0.636	0.97
278_T	282_A	0.635	0.97
170_M	383_F	0.635	0.97
133_S	422_E	0.632	0.97
448_L	452_E	0.632	0.97
310_A	397_N	0.631	0.97
400_R	407_K	0.631	0.97
292_S	352_L	0.630	0.97
341_F	352_L	0.628	0.97
163_L	284_L	0.624	0.97
221_S	225_L	0.624	0.97
210_V	272_Q	0.623	0.97
84_I	90_H	0.623	0.97
217_R	220_Q	0.622	0.97
61_L	74_G	0.622	0.97
159_L	376_I	0.621	0.97
336_I	390_C	0.620	0.97
60_A	138_V	0.617	0.97
455_I	461_E	0.617	0.97
137_H	140_M	0.616	0.97
81_A	114_I	0.614	0.97
308_G	400_R	0.613	0.97
68_R	141_S	0.613	0.97
160_L	164_L	0.611	0.97
249_V	254_A	0.607	0.96
64_M	78_V	0.605	0.96
349_T	368_L	0.604	0.96
216_K	227_E	0.603	0.96
438_V	442_C	0.602	0.96
285_K	289_M	0.602	0.96
332_M	386_F	0.602	0.96
291_M	387_T	0.602	0.96
178_A	182_D	0.601	0.96
217_R	224_H	0.600	0.96
404_Y	407_K	0.600	0.96
405_V	410_G	0.599	0.96
112_E	116_N	0.599	0.96
278_T	351_C	0.598	0.96
214_D	217_R	0.596	0.96
345_G	348_N	0.596	0.96
69_L	74_G	0.595	0.96
349_T	353_A	0.595	0.96
280_V	376_I	0.595	0.96
165_K	169_D	0.595	0.96
69_L	77_I	0.594	0.96
207_Y	210_V	0.594	0.96
317_R	393_G	0.593	0.96
221_S	280_V	0.590	0.96
420_G	423_A	0.590	0.96
406_E	437_S	0.590	0.96
308_G	312_I	0.589	0.96
179_Q	183_S	0.588	0.96
185_I	459_P	0.588	0.96
115_G	119_L	0.587	0.96
337_N	364_M	0.587	0.96
164_L	283_S	0.586	0.96
53_A	81_A	0.586	0.96
69_L	73_I	0.585	0.96
108_M	112_E	0.584	0.95
70_Y	74_G	0.583	0.95
163_L	379_M	0.581	0.95
284_L	379_M	0.581	0.95
177_K	394_I	0.580	0.95
218_I	283_S	0.579	0.95
175_K	178_A	0.579	0.95
425_A	429_R	0.578	0.95
455_I	458_N	0.577	0.95
430_E	436_Q	0.577	0.95
288_M	379_M	0.577	0.95
284_L	287_C	0.577	0.95
279_E	286_V	0.575	0.95
398_E	401_M	0.575	0.95
461_E	464_K	0.574	0.95
441_L	445_H	0.573	0.95
109_N	115_G	0.572	0.95
203_E	297_D	0.571	0.95
55_V	151_A	0.565	0.95
53_A	90_H	0.563	0.95
109_N	114_I	0.563	0.95
282_A	285_K	0.563	0.95
332_M	390_C	0.561	0.94
211_L	287_C	0.561	0.94
86_E	89_W	0.561	0.94
60_A	78_V	0.559	0.94
47_E	162_K	0.557	0.94
156_T	225_L	0.557	0.94
369_V	373_L	0.557	0.94
371_N	374_Q	0.557	0.94
116_N	123_G	0.556	0.94
167_M	218_I	0.555	0.94
49_I	88_K	0.555	0.94
212_E	216_K	0.552	0.94
448_L	453_L	0.550	0.94
211_L	291_M	0.550	0.94
54_I	58_A	0.550	0.94
295_A	337_N	0.549	0.94
194_D	410_G	0.549	0.94
217_R	286_V	0.549	0.94
339_I	378_I	0.549	0.94
51_A	54_I	0.548	0.94
53_A	87_G	0.548	0.94
144_T	229_N	0.547	0.94
170_M	173_V	0.547	0.94
292_S	356_A	0.547	0.94
234_A	323_I	0.547	0.94
286_V	354_S	0.546	0.94
440_D	443_L	0.545	0.94
223_Q	227_E	0.545	0.94
204_F	394_I	0.542	0.93
108_M	115_G	0.541	0.93
443_L	453_L	0.541	0.93
199_R	464_K	0.540	0.93
191_H	363_V	0.538	0.93
391_L	394_I	0.537	0.93
119_L	123_G	0.537	0.93
55_V	230_M	0.537	0.93
445_H	453_L	0.536	0.93
453_L	456_I	0.536	0.93
209_R	212_E	0.535	0.93
229_N	271_T	0.535	0.93
77_I	122_M	0.534	0.93
426_R	445_H	0.533	0.93
122_M	134_P	0.533	0.93
298_L	391_L	0.531	0.93
186_K	301_M	0.531	0.93
111_N	114_I	0.530	0.93
93_F	113_V	0.529	0.93
254_A	257_S	0.528	0.92
184_V	201_G	0.528	0.92
281_S	375_S	0.527	0.92
54_I	257_S	0.527	0.92
221_S	279_E	0.526	0.92
192_L	358_Q	0.526	0.92
107_N	315_P	0.524	0.92
300_L	303_S	0.522	0.92
89_W	92_Q	0.521	0.92
59_A	253_L	0.518	0.92
219_K	223_Q	0.518	0.92
354_S	365_E	0.517	0.92
157_L	225_L	0.516	0.92
198_I	202_Q	0.516	0.92
244_E	255_D	0.515	0.92
205_E	208_S	0.514	0.91
286_V	290_N	0.512	0.91
298_L	386_F	0.511	0.91
164_L	171_H	0.510	0.91
195_A	235_V	0.510	0.91
213_R	224_H	0.508	0.91
275_D	279_E	0.508	0.91
318_Q	331_V	0.508	0.91
432_I	435_G	0.507	0.91
412_I	424_A	0.506	0.91
142_Q	147_V	0.505	0.91
228_V	263_G	0.504	0.91
395_E	398_E	0.504	0.91
166_T	385_S	0.503	0.91
164_L	167_M	0.502	0.90
254_A	259_L	0.502	0.90
449_T	455_I	0.502	0.90
233_T	241_A	0.501	0.90
336_I	340_A	0.500	0.90
74_G	77_I	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1furA	4	0.9642	100	0.164	Contact Map
1yfmA	4	0.9411	100	0.165	Contact Map
1vdkA	4	0.9621	100	0.169	Contact Map
3r6qA	4	0.9747	100	0.173	Contact Map
3gtdA	4	0.9558	100	0.178	Contact Map
4hgvA	4	0.9684	100	0.178	Contact Map
3e04A	4	0.9663	100	0.18	Contact Map
1jswA	4	0.9621	100	0.181	Contact Map
3ocfA	4	0.9411	100	0.192	Contact Map
4admA	4	0.9537	100	0.194	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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