GREMLIN Database
COMGD - ComG operon protein 4
UniProt: P25956 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 143 (133)
Sequences: 237 (213)
Seq/√Len: 18.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
116_G133_L4.2171.00
53_D88_R3.5531.00
57_T68_T3.2420.99
113_P131_V3.2390.99
54_I70_I2.9180.99
131_V138_V2.6740.98
55_M59_Q2.6500.98
49_Q88_R2.5700.97
130_T139_N2.3870.95
10_G13_L2.3250.95
132_Y139_N2.2680.94
49_Q53_D2.1870.93
11_F14_L2.1330.92
24_S28_V2.1160.91
11_F17_L2.0450.90
53_D79_L2.0320.90
79_L88_R2.0280.90
12_T15_E1.8850.86
50_L129_I1.8520.85
61_A94_L1.7260.80
57_T70_I1.6810.78
61_A136_G1.6580.77
42_A81_I1.6120.75
90_Y96_I1.5570.73
30_V50_L1.5380.72
116_G132_Y1.5270.71
15_E19_V1.5020.70
61_A132_Y1.4710.68
118_K137_R1.4420.67
100_T117_G1.4230.66
11_F15_E1.3980.64
40_N71_L1.3790.63
59_Q102_K1.3620.62
50_L140_V1.3450.61
10_G15_E1.3320.60
21_S24_S1.3290.60
124_H127_Y1.2920.58
22_L98_L1.2890.58
25_I126_V1.2860.57
46_A134_G1.2770.57
107_F113_P1.2550.56
32_T43_V1.2170.53
26_L121_V1.2160.53
120_R133_L1.2160.53
85_V98_L1.1970.52
21_S54_I1.1860.51
44_R62_I1.1770.51
59_Q116_G1.1750.51
88_R100_T1.1720.50
133_L136_G1.1170.47
56_L60_T1.1010.46
58_Q134_G1.0920.45
118_K128_D1.0780.45
127_Y139_N1.0780.45
10_G53_D1.0720.44
22_L82_G1.0320.42
77_Y133_L1.0230.41
53_D134_G1.0070.40
55_M138_V1.0050.40
46_A121_V1.0030.40
12_T17_L1.0020.40
67_R106_E1.0020.40
62_I114_N0.9870.39
57_T107_F0.9820.39
15_E111_G0.9790.39
132_Y136_G0.9790.39
16_S112_H0.9760.38
79_L86_I0.9700.38
79_L117_G0.9630.38
112_H132_Y0.9550.37
128_D139_N0.9530.37
102_K119_I0.9170.35
68_T79_L0.9160.35
51_K134_G0.9000.34
17_L71_L0.8930.34
96_I110_K0.8900.34
113_P127_Y0.8800.33
121_V140_V0.8740.33
46_A94_L0.8590.32
127_Y135_S0.8560.32
23_A105_L0.8530.31
105_L116_G0.8530.31
32_T91_A0.8490.31
57_T72_F0.8490.31
100_T121_V0.8450.31
50_L113_P0.8400.31
74_K110_K0.8360.31
102_K133_L0.8300.30
65_Q110_K0.8260.30
23_A108_N0.8170.30
51_K105_L0.8130.29
132_Y138_V0.8130.29
122_K129_I0.8060.29
38_Y113_P0.8020.29
19_V69_K0.8020.29
14_L18_L0.8000.29
37_A131_V0.7980.29
14_L119_I0.7980.29
105_L138_V0.7830.28
10_G58_Q0.7830.28
47_A140_V0.7810.28
46_A59_Q0.7790.28
93_G140_V0.7730.27
43_V135_S0.7720.27
78_Q87_E0.7720.27
46_A91_A0.7710.27
68_T132_Y0.7700.27
56_L135_S0.7700.27
113_P138_V0.7700.27
11_F130_T0.7690.27
59_Q100_T0.7670.27
118_K129_I0.7670.27
20_L80_V0.7650.27
21_S86_I0.7630.27
21_S34_L0.7610.27
45_Q119_I0.7540.26
16_S19_V0.7480.26
40_N128_D0.7410.26
40_N89_P0.7400.26
54_I60_T0.7380.26
66_Q80_V0.7360.26
90_Y94_L0.7320.25
16_S47_A0.7240.25
59_Q133_L0.7230.25
44_R75_K0.7160.25
45_Q97_E0.7150.25
75_K90_Y0.7100.24
63_S73_H0.7090.24
18_L65_Q0.7000.24
94_L98_L0.6950.24
13_L45_Q0.6920.24
70_I123_G0.6910.23
111_G136_G0.6900.23
15_E20_L0.6890.23
100_T116_G0.6890.23
23_A136_G0.6870.23
48_S116_G0.6860.23
61_A68_T0.6860.23
30_V113_P0.6850.23
28_V32_T0.6810.23
60_T64_R0.6800.23
38_Y96_I0.6730.23
59_Q132_Y0.6650.22
33_T44_R0.6620.22
126_V129_I0.6610.22
18_L43_V0.6570.22
89_P107_F0.6490.22
84_T99_L0.6490.22
65_Q112_H0.6430.21
107_F132_Y0.6410.21
58_Q132_Y0.6400.21
29_A34_L0.6350.21
50_L127_Y0.6250.21
7_E14_L0.6100.20
46_A58_Q0.6080.20
9_K64_R0.6030.20
74_K91_A0.6030.20
21_S62_I0.6030.20
113_P116_G0.5970.20
43_V127_Y0.5960.20
53_D116_G0.5940.19
84_T107_F0.5930.19
110_K115_A0.5870.19
16_S35_P0.5850.19
60_T129_I0.5760.19
7_E11_F0.5730.19
91_A94_L0.5720.19
16_S102_K0.5700.19
94_L107_F0.5650.18
29_A124_H0.5640.18
37_A105_L0.5590.18
34_L125_A0.5580.18
81_I117_G0.5560.18
107_F111_G0.5540.18
52_N116_G0.5520.18
119_I133_L0.5510.18
16_S33_T0.5480.18
70_I96_I0.5460.18
45_Q90_Y0.5460.18
13_L22_L0.5440.18
77_Y139_N0.5400.17
49_Q126_V0.5390.17
47_A112_H0.5370.17
33_T51_K0.5370.17
17_L88_R0.5360.17
62_I116_G0.5360.17
82_G133_L0.5240.17
74_K107_F0.5240.17
33_T126_V0.5190.17
61_A114_N0.5190.17
91_A128_D0.5190.17
14_L28_V0.5170.17
31_F44_R0.5170.17
52_N55_M0.5140.16
28_V104_R0.5080.16
42_A70_I0.5080.16
64_R107_F0.5080.16
16_S130_T0.5050.16
108_N128_D0.5030.16
70_I91_A0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1oqwA 1 0.8601 97.8 0.805 Contact Map
4dq9A 2 0.7273 97.6 0.815 Contact Map
2m7gA 1 0.4266 97.3 0.825 Contact Map
4ipuA 1 0.7692 97.2 0.826 Contact Map
2hi2A 1 0.8741 96.8 0.837 Contact Map
3sokA 1 0.8392 96.7 0.84 Contact Map
2knqA 1 0.7762 91.3 0.878 Contact Map
3aqyA 1 0.4406 8.3 0.943 Contact Map
3ie4A 1 0.4476 8.2 0.943 Contact Map
3tzgA 1 0.4615 7 0.945 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0063 seconds.