GREMLIN Database
MNMG - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
UniProt: P25812 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 628 (615)
Sequences: 3085 (1712)
Seq/√Len: 69.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
253_E257_S4.9601.00
576_D590_K4.7871.00
218_I241_P4.6131.00
453_H460_D4.3791.00
386_M414_I3.7111.00
8_Y120_T3.5971.00
407_D451_I3.3901.00
193_F359_T3.3131.00
259_L285_V3.2281.00
246_Y292_R3.1581.00
249_P291_P3.1071.00
250_E253_E3.1001.00
403_L408_A3.0731.00
460_D464_A2.9371.00
574_D577_A2.9251.00
251_T327_T2.8881.00
113_L121_L2.8761.00
211_I307_V2.7131.00
75_I100_A2.6771.00
67_L452_G2.5801.00
194_D349_V2.5551.00
248_S329_P2.5471.00
453_H463_Y2.5371.00
352_Q361_K2.5181.00
363_T394_K2.5001.00
393_R398_K2.4721.00
74_N109_M2.4461.00
128_R187_H2.4401.00
261_R319_D2.4221.00
356_T400_E2.3951.00
452_G458_I2.3591.00
231_E462_R2.3581.00
149_A152_V2.3461.00
209_D305_Q2.3391.00
194_D352_Q2.3371.00
393_R401_V2.3091.00
471_A475_A2.3061.00
450_E454_R2.3041.00
450_E470_K2.2831.00
325_L334_V2.2821.00
476_E479_R2.2751.00
297_L331_L2.2371.00
77_K108_E2.2231.00
213_Y307_V2.2191.00
212_D215_K2.2061.00
60_V382_G2.1931.00
33_T119_L2.1901.00
31_A396_L2.1881.00
193_F361_K2.1771.00
216_T297_L2.1691.00
446_L470_K2.1191.00
32_K118_N2.1101.00
43_V121_L2.0981.00
24_L70_E2.0951.00
326_A334_V2.0891.00
132_E137_R2.0551.00
481_H510_T2.0541.00
7_Q148_R2.0531.00
463_Y467_E2.0471.00
215_K329_P2.0461.00
168_D261_R2.0441.00
555_L559_E2.0411.00
20_V44_A2.0351.00
325_L336_M2.0331.00
354_W358_E2.0031.00
401_V451_I1.9881.00
356_T366_Y1.9881.00
386_M410_I1.9751.00
257_S323_R1.9631.00
64_I381_A1.9591.00
196_V347_A1.9531.00
207_K210_T1.9511.00
161_R189_E1.9481.00
220_P241_P1.9451.00
135_E363_T1.9391.00
60_V428_L1.9221.00
169_L318_E1.9181.00
366_Y394_K1.8861.00
519_N522_T1.8811.00
208_S213_Y1.8761.00
185_S195_L1.8621.00
386_M408_A1.8551.00
34_L122_L1.8521.00
254_I327_T1.8501.00
355_P595_L1.8351.00
548_E552_E1.8281.00
153_V395_A1.8201.00
110_K114_E1.8131.00
265_Y285_V1.8121.00
128_R140_I1.8101.00
140_I146_H1.8081.00
128_R190_E1.8041.00
215_K332_E1.7991.00
204_P325_L1.7971.00
11_I149_A1.7971.00
108_E111_N1.7951.00
449_T458_I1.7941.00
151_A394_K1.7861.00
569_I573_I1.7841.00
151_A366_Y1.7681.00
585_A606_V1.7571.00
392_G396_L1.7531.00
7_Q150_K1.7481.00
393_R454_R1.7301.00
31_A392_G1.7151.00
40_L121_L1.7111.00
207_K335_Q1.7111.00
207_K305_Q1.7001.00
151_A395_A1.6951.00
259_L265_Y1.6951.00
510_T545_V1.6831.00
534_P537_V1.6720.99
29_Q393_R1.6650.99
449_T462_R1.6610.99
568_K595_L1.6590.99
13_I126_V1.6580.99
297_L307_V1.6510.99
472_A537_V1.6500.99
164_I173_S1.6370.99
250_E323_R1.6300.99
401_V455_I1.6270.99
77_K112_T1.6160.99
306_E337_M1.6160.99
64_I385_I1.5810.99
386_M403_L1.5760.99
116_E119_L1.5720.99
500_G517_E1.5680.99
131_V191_L1.5450.99
211_I216_T1.5440.99
10_V26_S1.5440.99
451_I454_R1.5410.99
322_Q336_M1.5360.99
227_A232_T1.5250.99
539_E543_I1.5220.99
189_E195_L1.5130.99
212_D333_N1.5080.99
75_I98_A1.5050.99
124_G141_T1.5030.99
484_I508_R1.5000.99
46_M100_A1.4860.99
576_D586_R1.4820.99
472_A534_P1.4770.99
445_D469_K1.4700.99
70_E74_N1.4690.99
597_V615_L1.4690.99
206_V211_I1.4680.99
358_E394_K1.4680.99
393_R396_L1.4450.98
552_E555_L1.4420.98
588_K603_I1.4340.98
364_N394_K1.4320.98
240_L302_R1.4260.98
36_L126_V1.4210.98
569_I590_K1.4180.98
73_R231_E1.4130.98
476_E541_V1.4090.98
206_V334_V1.4060.98
39_N42_M1.4030.98
476_E520_Y1.3960.98
52_V71_M1.3940.98
438_L558_V1.3900.98
104_Q107_H1.3890.98
80_I302_R1.3890.98
498_L522_T1.3890.98
469_K536_D1.3860.98
78_T108_E1.3860.98
231_E449_T1.3840.98
467_E470_K1.3840.98
314_T340_G1.3830.98
28_R70_E1.3820.98
385_I389_I1.3710.98
172_S180_P1.3670.98
216_T245_T1.3640.98
80_I240_L1.3610.98
231_E458_I1.3600.98
474_E478_K1.3590.98
585_A610_D1.3570.98
74_N112_T1.3550.98
208_S304_T1.3450.98
524_T538_A1.3430.98
187_H190_E1.3420.98
70_E112_T1.3380.97
483_V509_G1.3370.97
8_Y34_L1.3340.97
258_N261_R1.3340.97
355_P418_V1.3320.97
74_N108_E1.3310.97
476_E533_V1.3270.97
186_E190_E1.3240.97
13_I154_M1.3240.97
24_L116_E1.3240.97
130_I138_G1.3230.97
598_A602_R1.3090.97
204_P324_M1.3090.97
404_S562_K1.3040.97
470_K474_E1.3040.97
256_D288_N1.3030.97
468_K472_A1.3020.97
540_Q543_I1.2980.97
68_G459_S1.2960.97
590_K593_R1.2880.97
521_E538_A1.2850.97
463_Y466_F1.2850.97
81_Q221_G1.2840.97
61_V71_M1.2820.97
103_F303_N1.2780.97
172_S182_I1.2740.97
31_A395_A1.2730.97
449_T466_F1.2700.97
70_E109_M1.2620.96
412_V433_A1.2620.96
218_I243_W1.2570.96
9_D31_A1.2570.96
249_P253_E1.2560.96
79_H82_M1.2520.96
130_I146_H1.2510.96
253_E256_D1.2490.96
583_T587_Q1.2470.96
131_V362_I1.2440.96
36_L147_Y1.2390.96
26_S33_T1.2370.96
348_I367_T1.2310.96
460_D463_Y1.2280.96
227_A235_Y1.2270.96
38_I125_I1.2260.96
459_S462_R1.2180.96
350_P421_G1.2150.96
559_E562_K1.2150.96
245_T331_L1.2120.95
204_P334_V1.2100.95
473_I541_V1.2090.95
163_R170_S1.2080.95
208_S307_V1.2050.95
156_T371_I1.2040.95
181_S185_S1.2010.95
404_S407_D1.1990.95
478_K481_H1.1960.95
24_L28_R1.1910.95
297_L309_V1.1770.95
354_W595_L1.1730.95
464_A468_K1.1720.95
78_T104_Q1.1710.95
263_P266_S1.1710.95
382_G413_L1.1700.95
519_N542_E1.1700.95
583_T586_R1.1580.94
84_M441_H1.1580.94
98_A221_G1.1500.94
161_R182_I1.1490.94
161_R185_S1.1470.94
249_P256_D1.1450.94
356_T393_R1.1430.94
478_K482_S1.1430.94
587_Q591_N1.1390.94
573_I617_Y1.1330.94
446_L540_Q1.1320.93
131_V134_G1.1290.93
9_D150_K1.1240.93
187_H191_L1.1220.93
124_G143_T1.1140.93
40_L123_Q1.1110.93
233_V465_A1.1100.93
446_L544_Q1.1100.93
29_Q396_L1.1100.93
183_K186_E1.1100.93
392_G395_A1.1090.93
496_R502_E1.1090.93
250_E327_T1.1040.93
573_I578_I1.1020.93
571_D595_L1.0990.92
481_H548_E1.0960.92
153_V366_Y1.0930.92
40_L110_K1.0880.92
96_L441_H1.0860.92
312_L328_I1.0810.92
29_Q455_I1.0810.92
20_V113_L1.0810.92
477_K544_Q1.0790.92
11_I34_L1.0790.92
132_E148_R1.0760.92
479_R520_Y1.0720.92
20_V109_M1.0720.92
258_N320_V1.0700.91
322_Q326_A1.0690.91
252_H256_D1.0660.91
52_V61_V1.0660.91
255_I280_I1.0650.91
552_E556_Q1.0640.91
248_S252_H1.0620.91
569_I575_Y1.0610.91
446_L473_I1.0580.91
102_K300_E1.0570.91
244_L294_Q1.0550.91
597_V611_I1.0540.91
136_C364_N1.0530.91
36_L122_L1.0530.91
94_R539_E1.0520.91
162_G180_P1.0500.91
572_R593_R1.0480.91
211_I297_L1.0460.90
565_E602_R1.0460.90
231_E461_E1.0450.90
186_E189_E1.0410.90
312_L325_L1.0390.90
35_V113_L1.0390.90
103_F107_H1.0360.90
70_E73_R1.0360.90
464_A467_E1.0350.90
468_K471_A1.0350.90
58_G228_F1.0330.90
406_S562_K1.0330.90
561_L598_A1.0280.90
154_M188_L1.0220.89
26_S31_A1.0220.89
565_E598_A1.0200.89
127_E142_Q1.0160.89
139_V152_V1.0140.89
208_S305_Q1.0120.89
586_R590_K1.0030.89
41_D123_Q1.0010.88
131_V187_H0.9950.88
477_K481_H0.9920.88
130_I137_R0.9910.88
494_Y498_L0.9880.88
389_I457_L0.9830.88
10_V395_A0.9780.87
10_V151_A0.9760.87
68_G73_R0.9720.87
159_Y175_P0.9700.87
36_L124_G0.9670.87
433_A439_L0.9660.87
129_L149_A0.9650.87
398_K454_R0.9580.86
366_Y395_A0.9560.86
114_E121_L0.9560.86
40_L114_E0.9530.86
322_Q335_Q0.9510.86
322_Q325_L0.9480.86
206_V331_L0.9460.85
127_E183_K0.9450.85
301_G304_T0.9450.85
476_E530_E0.9430.85
32_K120_T0.9420.85
599_Q602_R0.9380.85
315_S342_A0.9340.85
130_I140_I0.9280.84
64_I71_M0.9280.84
312_L324_M0.9270.84
130_I148_R0.9260.84
582_A585_A0.9250.84
422_T588_K0.9170.84
569_I618_L0.9160.84
175_P178_Q0.9150.83
168_D260_H0.9140.83
198_F347_A0.9130.83
295_I312_L0.9130.83
29_Q457_L0.9130.83
410_I414_I0.9120.83
141_T147_Y0.9110.83
55_P95_A0.9070.83
6_G32_K0.9020.83
193_F348_I0.9010.83
194_D361_K0.9000.82
52_V75_I0.8990.82
393_R455_I0.8970.82
193_F367_T0.8950.82
136_C363_T0.8950.82
150_K395_A0.8950.82
245_T295_I0.8950.82
554_S557_Q0.8940.82
161_R195_L0.8930.82
211_I331_L0.8930.82
15_A35_V0.8880.82
137_R148_R0.8870.82
165_I268_M0.8870.82
182_I185_S0.8850.81
288_N292_R0.8840.81
484_I506_G0.8840.81
452_G460_D0.8810.81
318_E322_Q0.8800.81
261_R320_V0.8790.81
120_T335_Q0.8760.81
82_M429_L0.8760.81
216_T331_L0.8750.81
518_M522_T0.8720.80
195_L348_I0.8720.80
601_S611_I0.8690.80
445_D449_T0.8670.80
324_M327_T0.8670.80
20_V74_N0.8660.80
592_V603_I0.8650.80
452_G457_L0.8630.80
580_G586_R0.8630.80
170_S268_M0.8600.79
453_H459_S0.8590.79
480_L509_G0.8580.79
453_H467_E0.8550.79
571_D593_R0.8520.79
450_E453_H0.8510.79
216_T328_I0.8490.79
55_P429_L0.8470.78
125_I183_K0.8470.78
36_L139_V0.8470.78
495_I500_G0.8460.78
24_L113_L0.8440.78
221_G239_Q0.8440.78
607_N610_D0.8430.78
111_N115_K0.8410.78
122_L147_Y0.8400.78
422_T604_S0.8400.78
137_R363_T0.8380.78
207_K337_M0.8370.78
125_I142_Q0.8360.78
153_V389_I0.8360.78
612_S616_V0.8360.78
494_Y497_S0.8320.77
522_T525_K0.8310.77
260_H263_P0.8300.77
326_A335_Q0.8300.77
11_I147_Y0.8270.77
572_R621_G0.8270.77
354_W571_D0.8260.77
520_Y538_A0.8250.77
389_I393_R0.8240.77
78_T100_A0.8200.76
406_S561_L0.8170.76
322_Q339_A0.8160.76
450_E467_E0.8160.76
104_Q108_E0.8140.76
396_L454_R0.8120.75
336_M339_A0.8110.75
129_L152_V0.8060.75
326_A333_N0.8050.75
56_A59_I0.8050.75
350_P422_T0.8030.75
389_I401_V0.8020.75
474_E477_K0.8010.74
386_M401_V0.7990.74
150_K364_N0.7980.74
60_V413_L0.7970.74
472_A475_A0.7970.74
59_I95_A0.7950.74
193_F362_I0.7930.74
348_I352_Q0.7920.74
123_Q306_E0.7910.74
84_M96_L0.7910.74
131_V137_R0.7890.73
138_G152_V0.7890.73
33_T116_E0.7870.73
206_V309_V0.7870.73
513_M545_V0.7870.73
354_W363_T0.7860.73
266_S285_V0.7850.73
45_F176_N0.7790.72
138_G149_A0.7780.72
168_D266_S0.7770.72
579_K586_R0.7760.72
250_E257_S0.7750.72
592_V599_Q0.7740.72
231_E465_A0.7710.72
250_E254_I0.7680.71
47_P429_L0.7680.71
149_A364_N0.7660.71
318_E339_A0.7660.71
216_T329_P0.7650.71
40_L337_M0.7650.71
295_I309_V0.7650.71
404_S561_L0.7640.71
161_R186_E0.7640.71
129_L136_C0.7620.71
446_L466_F0.7620.71
466_F470_K0.7620.71
255_I284_V0.7580.70
367_T371_I0.7580.70
503_L507_V0.7580.70
475_A478_K0.7570.70
24_L112_T0.7540.70
62_R96_L0.7530.70
163_R172_S0.7510.70
558_V561_L0.7510.70
42_M178_Q0.7500.70
288_N291_P0.7490.69
243_W307_V0.7480.69
477_K541_V0.7480.69
25_A457_L0.7480.69
382_G428_L0.7470.69
108_E112_T0.7470.69
129_L138_G0.7470.69
210_T335_Q0.7450.69
40_L113_L0.7430.69
603_I606_V0.7430.69
570_P593_R0.7410.69
107_H303_N0.7410.69
399_E454_R0.7390.68
449_T452_G0.7390.68
34_L147_Y0.7380.68
73_R112_T0.7350.68
110_K337_M0.7350.68
115_K305_Q0.7350.68
56_A428_L0.7350.68
102_K309_V0.7350.68
51_S310_Q0.7330.68
68_G462_R0.7320.68
12_V26_S0.7320.68
559_E563_K0.7310.68
542_E546_K0.7290.67
137_R150_K0.7270.67
204_P340_G0.7260.67
404_S598_A0.7250.67
137_R140_I0.7250.67
477_K545_V0.7250.67
134_G363_T0.7250.67
498_L518_M0.7240.67
224_V535_Q0.7220.67
309_V334_V0.7210.66
154_M367_T0.7190.66
165_I343_I0.7190.66
238_D302_R0.7160.66
265_Y282_D0.7160.66
435_Y558_V0.7160.66
366_Y393_R0.7160.66
168_D268_M0.7150.66
11_I139_V0.7150.66
419_T599_Q0.7140.66
469_K540_Q0.7140.66
165_I170_S0.7140.66
29_Q392_G0.7130.66
501_S517_E0.7130.66
213_Y243_W0.7100.65
62_R441_H0.7100.65
486_K506_G0.7100.65
96_L310_Q0.7090.65
479_R483_V0.7090.65
409_Y433_A0.7090.65
252_H284_V0.7090.65
521_E535_Q0.7080.65
561_L611_I0.7080.65
585_A607_N0.7070.65
497_S525_K0.7030.65
509_G527_A0.7020.64
245_T329_P0.7020.64
413_L428_L0.7000.64
168_D263_P0.7000.64
514_K548_E0.7000.64
41_D110_K0.6970.64
305_Q337_M0.6960.64
13_I156_T0.6950.64
209_D335_Q0.6940.64
166_L339_A0.6930.63
58_G84_M0.6930.63
38_I42_M0.6920.63
80_I301_G0.6920.63
141_T263_P0.6910.63
70_E113_L0.6910.63
42_M45_F0.6880.63
453_H466_F0.6880.63
540_Q544_Q0.6870.63
266_S282_D0.6860.63
356_T401_V0.6850.63
556_Q559_E0.6850.63
429_L607_N0.6850.63
142_Q179_Q0.6850.63
11_I126_V0.6840.62
68_G457_L0.6820.62
357_L414_I0.6820.62
47_P55_P0.6810.62
140_I187_H0.6810.62
44_A102_K0.6810.62
420_K604_S0.6800.62
175_P343_I0.6780.62
359_T362_I0.6770.62
87_T94_R0.6770.62
78_T98_A0.6760.61
15_A109_M0.6760.61
349_V352_Q0.6750.61
217_E292_R0.6750.61
282_D315_S0.6750.61
10_V31_A0.6740.61
208_S243_W0.6730.61
250_E329_P0.6710.61
530_E533_V0.6710.61
264_M319_D0.6700.61
136_C152_V0.6700.61
325_L340_G0.6700.61
408_A412_V0.6680.61
487_P503_L0.6660.60
382_G410_I0.6660.60
450_E466_F0.6650.60
252_H292_R0.6650.60
59_I428_L0.6650.60
355_P419_T0.6650.60
75_I228_F0.6640.60
360_K592_V0.6640.60
323_R326_A0.6630.60
323_R327_T0.6630.60
309_V610_D0.6620.60
485_I493_E0.6610.60
446_L450_E0.6590.60
489_P493_E0.6590.60
62_R84_M0.6590.60
489_P492_Q0.6590.60
319_D323_R0.6580.59
192_G352_Q0.6570.59
306_E338_R0.6570.59
513_M523_V0.6560.59
77_K111_N0.6560.59
489_P506_G0.6560.59
64_I382_G0.6550.59
74_N100_A0.6550.59
572_R618_L0.6540.59
280_I314_T0.6520.59
81_Q239_Q0.6510.59
83_R219_Q0.6500.58
261_R317_P0.6500.58
317_P320_V0.6490.58
220_P223_D0.6470.58
399_E568_K0.6460.58
160_L181_S0.6450.58
413_L588_K0.6450.58
82_M98_A0.6440.58
512_L518_M0.6440.58
111_N303_N0.6430.58
104_Q302_R0.6430.58
518_M523_V0.6410.57
28_R116_E0.6410.57
252_H288_N0.6390.57
159_Y162_G0.6390.57
242_C299_P0.6390.57
255_I324_M0.6390.57
247_T280_I0.6380.57
110_K123_Q0.6380.57
127_E140_I0.6380.57
582_A607_N0.6380.57
372_N383_Q0.6380.57
175_P429_L0.6370.57
458_I466_F0.6370.57
533_V538_A0.6370.57
493_E496_R0.6360.57
266_S271_G0.6360.57
349_V421_G0.6340.57
248_S327_T0.6340.57
24_L74_N0.6340.57
194_D591_N0.6330.56
110_K207_K0.6320.56
359_T371_I0.6320.56
367_T429_L0.6310.56
164_I343_I0.6310.56
246_Y291_P0.6310.56
10_V153_V0.6290.56
359_T367_T0.6280.56
388_G391_A0.6260.56
492_Q495_I0.6250.56
15_A44_A0.6250.56
309_V312_L0.6250.56
359_T363_T0.6240.55
258_N265_Y0.6240.55
47_P82_M0.6210.55
513_M518_M0.6200.55
271_G382_G0.6190.55
159_Y178_Q0.6190.55
471_A474_E0.6190.55
258_N316_L0.6190.55
579_K613_I0.6180.55
508_R581_I0.6170.55
533_V537_V0.6160.54
45_F123_Q0.6160.54
199_K313_S0.6150.54
155_T347_A0.6150.54
47_P175_P0.6140.54
464_A475_A0.6130.54
453_H458_I0.6120.54
474_E481_H0.6120.54
187_H362_I0.6120.54
351_T421_G0.6110.54
215_K330_G0.6110.54
70_E116_E0.6090.54
450_E463_Y0.6090.54
258_N324_M0.6080.54
130_I152_V0.6080.54
94_R441_H0.6070.53
98_A228_F0.6070.53
251_T254_I0.6060.53
268_M271_G0.6060.53
47_P310_Q0.6050.53
259_L266_S0.6050.53
55_P82_M0.6040.53
479_R530_E0.6040.53
263_P268_M0.6040.53
51_S55_P0.6020.53
153_V392_G0.6010.53
569_I576_D0.6010.53
493_E497_S0.6010.53
408_A422_T0.6000.53
79_H225_P0.5990.52
261_R323_R0.5990.52
612_S615_L0.5980.52
264_M315_S0.5980.52
487_P506_G0.5980.52
26_S151_A0.5970.52
168_D319_D0.5970.52
23_A35_V0.5960.52
327_T334_V0.5960.52
476_E480_L0.5950.52
47_P159_Y0.5950.52
82_M96_L0.5950.52
256_D284_V0.5940.52
123_Q338_R0.5930.52
257_S260_H0.5920.52
187_H195_L0.5910.51
38_I181_S0.5900.51
127_E144_G0.5900.51
328_I332_E0.5900.51
13_I152_V0.5900.51
237_T302_R0.5890.51
227_A428_L0.5880.51
578_I581_I0.5880.51
45_F102_K0.5880.51
51_S80_I0.5880.51
165_I429_L0.5870.51
214_S333_N0.5850.51
435_Y554_S0.5850.51
44_A109_M0.5840.51
47_P96_L0.5830.51
511_D514_K0.5830.51
348_I597_V0.5830.51
26_S34_L0.5820.50
535_Q539_E0.5820.50
422_T438_L0.5820.50
199_K269_I0.5810.50
274_P313_S0.5800.50
442_D540_Q0.5800.50
284_V314_T0.5790.50
324_M328_I0.5790.50
467_E471_A0.5790.50
323_R329_P0.5770.50
403_L455_I0.5770.50
533_V541_V0.5770.50
261_R264_M0.5760.50
165_I310_Q0.5750.50
175_P347_A0.5750.50
520_Y533_V0.5750.50
235_Y238_D0.5750.50
219_Q242_C0.5720.49
537_V540_Q0.5720.49
520_Y531_V0.5720.49
129_L154_M0.5710.49
207_K304_T0.5710.49
163_R173_S0.5700.49
472_A541_V0.5690.49
26_S30_G0.5690.49
13_I603_I0.5680.49
95_A429_L0.5680.49
129_L187_H0.5680.49
55_P58_G0.5680.49
488_S492_Q0.5680.49
132_E146_H0.5670.49
159_Y429_L0.5670.49
15_A43_V0.5670.49
245_T328_I0.5670.49
163_R270_K0.5660.48
315_S319_D0.5660.48
504_K507_V0.5650.48
185_S189_E0.5650.48
382_G385_I0.5650.48
163_R181_S0.5650.48
527_A530_E0.5650.48
401_V454_R0.5630.48
395_A398_K0.5630.48
461_E464_A0.5630.48
11_I129_L0.5620.48
388_G392_G0.5610.48
267_G342_A0.5600.48
166_L169_L0.5590.48
267_G282_D0.5590.48
55_P96_L0.5590.48
348_I359_T0.5580.47
130_I149_A0.5580.47
318_E336_M0.5560.47
109_M113_L0.5560.47
225_P235_Y0.5560.47
122_L335_Q0.5550.47
29_Q386_M0.5550.47
487_P495_I0.5540.47
183_K188_L0.5540.47
175_P310_Q0.5520.47
258_N323_R0.5500.47
136_C149_A0.5490.46
15_A121_L0.5490.46
112_T115_K0.5480.46
201_G313_S0.5470.46
492_Q503_L0.5470.46
503_L506_G0.5460.46
315_S550_Y0.5450.46
520_Y542_E0.5450.46
141_T145_A0.5450.46
6_G145_A0.5440.46
429_L441_H0.5440.46
257_S320_V0.5440.46
20_V23_A0.5440.46
568_K596_S0.5440.46
45_F106_Q0.5430.46
231_E459_S0.5430.46
567_K618_L0.5430.46
51_S297_L0.5430.46
217_E244_L0.5430.46
117_P209_D0.5420.46
355_P402_I0.5410.45
104_Q303_N0.5410.45
579_K617_Y0.5400.45
280_I296_F0.5380.45
56_A95_A0.5380.45
191_L362_I0.5380.45
56_A375_S0.5360.45
264_M342_A0.5360.45
310_Q429_L0.5360.45
503_L515_R0.5360.45
497_S502_E0.5360.45
258_N266_S0.5350.45
399_E471_A0.5340.45
203_P313_S0.5340.45
71_M105_Y0.5340.45
403_L407_D0.5340.45
209_D304_T0.5330.45
163_R271_G0.5330.45
309_V325_L0.5330.45
544_Q548_E0.5330.45
510_T514_K0.5330.45
569_I621_G0.5320.44
60_V155_T0.5320.44
79_H429_L0.5300.44
156_T348_I0.5300.44
170_S262_S0.5300.44
509_G518_M0.5300.44
138_G146_H0.5290.44
181_S187_H0.5270.44
66_A445_D0.5270.44
435_Y553_K0.5260.44
296_F314_T0.5260.44
273_G313_S0.5250.44
47_P198_F0.5250.44
254_I323_R0.5250.44
458_I462_R0.5240.43
6_G120_T0.5240.43
413_L604_S0.5240.43
55_P94_R0.5240.43
435_Y565_E0.5240.43
25_A28_R0.5240.43
59_I409_Y0.5230.43
45_F178_Q0.5230.43
575_Y590_K0.5230.43
9_D32_K0.5230.43
505_D511_D0.5230.43
181_S189_E0.5230.43
285_V431_S0.5230.43
135_E394_K0.5220.43
356_T396_L0.5220.43
82_M165_I0.5220.43
164_I171_Y0.5220.43
126_V139_V0.5220.43
73_R77_K0.5220.43
414_I498_L0.5210.43
326_A336_M0.5200.43
310_Q328_I0.5200.43
577_A621_G0.5200.43
488_S495_I0.5190.43
347_A429_L0.5190.43
280_I316_L0.5190.43
360_K599_Q0.5180.43
134_G137_R0.5170.43
461_E465_A0.5170.43
294_Q439_L0.5170.43
357_L386_M0.5160.42
47_P347_A0.5160.42
442_D543_I0.5160.42
143_T318_E0.5150.42
58_G88_G0.5150.42
320_V323_R0.5140.42
422_T603_I0.5140.42
264_M269_I0.5140.42
245_T309_V0.5140.42
566_N578_I0.5130.42
150_K454_R0.5130.42
109_M112_T0.5120.42
259_L324_M0.5120.42
255_I316_L0.5120.42
173_S553_K0.5110.42
272_T587_Q0.5100.42
487_P505_D0.5100.42
13_I23_A0.5100.42
473_I544_Q0.5100.42
250_E471_A0.5090.42
264_M282_D0.5090.42
162_G542_E0.5090.42
451_I455_I0.5080.42
510_T548_E0.5080.42
129_L146_H0.5080.42
389_I455_I0.5060.41
137_R149_A0.5060.41
102_K216_T0.5060.41
162_G166_L0.5050.41
441_H607_N0.5050.41
282_D296_F0.5040.41
479_R533_V0.5040.41
258_N319_D0.5040.41
246_Y288_N0.5040.41
286_R583_T0.5040.41
103_F106_Q0.5040.41
446_L469_K0.5040.41
149_A523_V0.5040.41
105_Y109_M0.5040.41
490_E495_I0.5030.41
274_P375_S0.5020.41
288_N413_L0.5020.41
91_P442_D0.5020.41
536_D568_K0.5010.41
262_S315_S0.5010.41
262_S268_M0.5010.41
282_D342_A0.5010.41
71_M75_I0.5010.41
529_P532_P0.5010.41
606_V609_A0.5000.41
423_N588_K0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cesA 2 0.828 100 0.365 Contact Map
3cp8A 2 0.9586 100 0.372 Contact Map
2zxiA 2 0.949 100 0.401 Contact Map
3g5sA 1 0.6162 100 0.724 Contact Map
2culA 1 0.3535 100 0.88 Contact Map
3v76A 2 0.5318 100 0.892 Contact Map
3nlcA 1 0.5844 100 0.894 Contact Map
4cnkA 2 0.5414 100 0.908 Contact Map
2i0zA 1 0.5541 99.8 0.931 Contact Map
3gyxA 2 0.7707 99.7 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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