MNMG - BACSU - GREMLIN Contacts

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MNMG - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

UniProt:	P25812	Sequences: MGYEAGQYDVIVIGAGHAGVEAALASARQGAKTLVLTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTHIQMRMLNTGKGPAVRALRAQADKFQYQHEMKNTLEKEPNLTLLQGIVERLIVEDGECRGVITQTGAHYRAKAVVMTTGTYLRGRIILGDLSYSSGPNNQQPSIKLSEHLEELGFDLVRFKTGTPPRVKSDTIDYSKTEIQPGDDVPRAFSYETVEYITDQLPCWLTYTSPETHEIIDSNLHRSPMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQQRMLATIPGLENVQMMRAGYAIEYDAIVPTQLWPTLETKKITNLYTAGQINGTSGYEEAAGQGIMAGINAGRKALGKEEVILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTEIGHRIGLISDERYAAFEKKKAAIEAEKKRLHSVIIKPSPENQEYIRSLGGSELKDGVRGTDLMKRPEMNYETVTKLAPPEVPVPQDVAEQVEIQVKYEGYIEKSLQQVEKLKKMENKKIPDRIDYDAIKGIATEARQKLKNVRPLSVAQASRISGVNPADISILLVYLEQGRIAKIAE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	628 (615)
Sequences:	3085 (1712)
Seq/√Len:	69.0

ECOLI - MNMG
BACSU - MNMG TRMFO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
253_E	257_S	4.960	1.00
576_D	590_K	4.787	1.00
218_I	241_P	4.613	1.00
453_H	460_D	4.379	1.00
386_M	414_I	3.711	1.00
8_Y	120_T	3.597	1.00
407_D	451_I	3.390	1.00
193_F	359_T	3.313	1.00
259_L	285_V	3.228	1.00
246_Y	292_R	3.158	1.00
249_P	291_P	3.107	1.00
250_E	253_E	3.100	1.00
403_L	408_A	3.073	1.00
460_D	464_A	2.937	1.00
574_D	577_A	2.925	1.00
251_T	327_T	2.888	1.00
113_L	121_L	2.876	1.00
211_I	307_V	2.713	1.00
75_I	100_A	2.677	1.00
67_L	452_G	2.580	1.00
194_D	349_V	2.555	1.00
248_S	329_P	2.547	1.00
453_H	463_Y	2.537	1.00
352_Q	361_K	2.518	1.00
363_T	394_K	2.500	1.00
393_R	398_K	2.472	1.00
74_N	109_M	2.446	1.00
128_R	187_H	2.440	1.00
261_R	319_D	2.422	1.00
356_T	400_E	2.395	1.00
452_G	458_I	2.359	1.00
231_E	462_R	2.358	1.00
149_A	152_V	2.346	1.00
209_D	305_Q	2.339	1.00
194_D	352_Q	2.337	1.00
393_R	401_V	2.309	1.00
471_A	475_A	2.306	1.00
450_E	454_R	2.304	1.00
450_E	470_K	2.283	1.00
325_L	334_V	2.282	1.00
476_E	479_R	2.275	1.00
297_L	331_L	2.237	1.00
77_K	108_E	2.223	1.00
213_Y	307_V	2.219	1.00
212_D	215_K	2.206	1.00
60_V	382_G	2.193	1.00
33_T	119_L	2.190	1.00
31_A	396_L	2.188	1.00
193_F	361_K	2.177	1.00
216_T	297_L	2.169	1.00
446_L	470_K	2.119	1.00
32_K	118_N	2.110	1.00
43_V	121_L	2.098	1.00
24_L	70_E	2.095	1.00
326_A	334_V	2.089	1.00
132_E	137_R	2.055	1.00
481_H	510_T	2.054	1.00
7_Q	148_R	2.053	1.00
463_Y	467_E	2.047	1.00
215_K	329_P	2.046	1.00
168_D	261_R	2.044	1.00
555_L	559_E	2.041	1.00
20_V	44_A	2.035	1.00
325_L	336_M	2.033	1.00
354_W	358_E	2.003	1.00
401_V	451_I	1.988	1.00
356_T	366_Y	1.988	1.00
386_M	410_I	1.975	1.00
257_S	323_R	1.963	1.00
64_I	381_A	1.959	1.00
196_V	347_A	1.953	1.00
207_K	210_T	1.951	1.00
161_R	189_E	1.948	1.00
220_P	241_P	1.945	1.00
135_E	363_T	1.939	1.00
60_V	428_L	1.922	1.00
169_L	318_E	1.918	1.00
366_Y	394_K	1.886	1.00
519_N	522_T	1.881	1.00
208_S	213_Y	1.876	1.00
185_S	195_L	1.862	1.00
386_M	408_A	1.855	1.00
34_L	122_L	1.852	1.00
254_I	327_T	1.850	1.00
355_P	595_L	1.835	1.00
548_E	552_E	1.828	1.00
153_V	395_A	1.820	1.00
110_K	114_E	1.813	1.00
265_Y	285_V	1.812	1.00
128_R	140_I	1.810	1.00
140_I	146_H	1.808	1.00
128_R	190_E	1.804	1.00
215_K	332_E	1.799	1.00
204_P	325_L	1.797	1.00
11_I	149_A	1.797	1.00
108_E	111_N	1.795	1.00
449_T	458_I	1.794	1.00
151_A	394_K	1.786	1.00
569_I	573_I	1.784	1.00
151_A	366_Y	1.768	1.00
585_A	606_V	1.757	1.00
392_G	396_L	1.753	1.00
7_Q	150_K	1.748	1.00
393_R	454_R	1.730	1.00
31_A	392_G	1.715	1.00
40_L	121_L	1.711	1.00
207_K	335_Q	1.711	1.00
207_K	305_Q	1.700	1.00
151_A	395_A	1.695	1.00
259_L	265_Y	1.695	1.00
510_T	545_V	1.683	1.00
534_P	537_V	1.672	0.99
29_Q	393_R	1.665	0.99
449_T	462_R	1.661	0.99
568_K	595_L	1.659	0.99
13_I	126_V	1.658	0.99
297_L	307_V	1.651	0.99
472_A	537_V	1.650	0.99
164_I	173_S	1.637	0.99
250_E	323_R	1.630	0.99
401_V	455_I	1.627	0.99
77_K	112_T	1.616	0.99
306_E	337_M	1.616	0.99
64_I	385_I	1.581	0.99
386_M	403_L	1.576	0.99
116_E	119_L	1.572	0.99
500_G	517_E	1.568	0.99
131_V	191_L	1.545	0.99
211_I	216_T	1.544	0.99
10_V	26_S	1.544	0.99
451_I	454_R	1.541	0.99
322_Q	336_M	1.536	0.99
227_A	232_T	1.525	0.99
539_E	543_I	1.522	0.99
189_E	195_L	1.513	0.99
212_D	333_N	1.508	0.99
75_I	98_A	1.505	0.99
124_G	141_T	1.503	0.99
484_I	508_R	1.500	0.99
46_M	100_A	1.486	0.99
576_D	586_R	1.482	0.99
472_A	534_P	1.477	0.99
445_D	469_K	1.470	0.99
70_E	74_N	1.469	0.99
597_V	615_L	1.469	0.99
206_V	211_I	1.468	0.99
358_E	394_K	1.468	0.99
393_R	396_L	1.445	0.98
552_E	555_L	1.442	0.98
588_K	603_I	1.434	0.98
364_N	394_K	1.432	0.98
240_L	302_R	1.426	0.98
36_L	126_V	1.421	0.98
569_I	590_K	1.418	0.98
73_R	231_E	1.413	0.98
476_E	541_V	1.409	0.98
206_V	334_V	1.406	0.98
39_N	42_M	1.403	0.98
476_E	520_Y	1.396	0.98
52_V	71_M	1.394	0.98
438_L	558_V	1.390	0.98
104_Q	107_H	1.389	0.98
80_I	302_R	1.389	0.98
498_L	522_T	1.389	0.98
469_K	536_D	1.386	0.98
78_T	108_E	1.386	0.98
231_E	449_T	1.384	0.98
467_E	470_K	1.384	0.98
314_T	340_G	1.383	0.98
28_R	70_E	1.382	0.98
385_I	389_I	1.371	0.98
172_S	180_P	1.367	0.98
216_T	245_T	1.364	0.98
80_I	240_L	1.361	0.98
231_E	458_I	1.360	0.98
474_E	478_K	1.359	0.98
585_A	610_D	1.357	0.98
74_N	112_T	1.355	0.98
208_S	304_T	1.345	0.98
524_T	538_A	1.343	0.98
187_H	190_E	1.342	0.98
70_E	112_T	1.338	0.97
483_V	509_G	1.337	0.97
8_Y	34_L	1.334	0.97
258_N	261_R	1.334	0.97
355_P	418_V	1.332	0.97
74_N	108_E	1.331	0.97
476_E	533_V	1.327	0.97
186_E	190_E	1.324	0.97
13_I	154_M	1.324	0.97
24_L	116_E	1.324	0.97
130_I	138_G	1.323	0.97
598_A	602_R	1.309	0.97
204_P	324_M	1.309	0.97
404_S	562_K	1.304	0.97
470_K	474_E	1.304	0.97
256_D	288_N	1.303	0.97
468_K	472_A	1.302	0.97
540_Q	543_I	1.298	0.97
68_G	459_S	1.296	0.97
590_K	593_R	1.288	0.97
521_E	538_A	1.285	0.97
463_Y	466_F	1.285	0.97
81_Q	221_G	1.284	0.97
61_V	71_M	1.282	0.97
103_F	303_N	1.278	0.97
172_S	182_I	1.274	0.97
31_A	395_A	1.273	0.97
449_T	466_F	1.270	0.97
70_E	109_M	1.262	0.96
412_V	433_A	1.262	0.96
218_I	243_W	1.257	0.96
9_D	31_A	1.257	0.96
249_P	253_E	1.256	0.96
79_H	82_M	1.252	0.96
130_I	146_H	1.251	0.96
253_E	256_D	1.249	0.96
583_T	587_Q	1.247	0.96
131_V	362_I	1.244	0.96
36_L	147_Y	1.239	0.96
26_S	33_T	1.237	0.96
348_I	367_T	1.231	0.96
460_D	463_Y	1.228	0.96
227_A	235_Y	1.227	0.96
38_I	125_I	1.226	0.96
459_S	462_R	1.218	0.96
350_P	421_G	1.215	0.96
559_E	562_K	1.215	0.96
245_T	331_L	1.212	0.95
204_P	334_V	1.210	0.95
473_I	541_V	1.209	0.95
163_R	170_S	1.208	0.95
208_S	307_V	1.205	0.95
156_T	371_I	1.204	0.95
181_S	185_S	1.201	0.95
404_S	407_D	1.199	0.95
478_K	481_H	1.196	0.95
24_L	28_R	1.191	0.95
297_L	309_V	1.177	0.95
354_W	595_L	1.173	0.95
464_A	468_K	1.172	0.95
78_T	104_Q	1.171	0.95
263_P	266_S	1.171	0.95
382_G	413_L	1.170	0.95
519_N	542_E	1.170	0.95
583_T	586_R	1.158	0.94
84_M	441_H	1.158	0.94
98_A	221_G	1.150	0.94
161_R	182_I	1.149	0.94
161_R	185_S	1.147	0.94
249_P	256_D	1.145	0.94
356_T	393_R	1.143	0.94
478_K	482_S	1.143	0.94
587_Q	591_N	1.139	0.94
573_I	617_Y	1.133	0.94
446_L	540_Q	1.132	0.93
131_V	134_G	1.129	0.93
9_D	150_K	1.124	0.93
187_H	191_L	1.122	0.93
124_G	143_T	1.114	0.93
40_L	123_Q	1.111	0.93
233_V	465_A	1.110	0.93
446_L	544_Q	1.110	0.93
29_Q	396_L	1.110	0.93
183_K	186_E	1.110	0.93
392_G	395_A	1.109	0.93
496_R	502_E	1.109	0.93
250_E	327_T	1.104	0.93
573_I	578_I	1.102	0.93
571_D	595_L	1.099	0.92
481_H	548_E	1.096	0.92
153_V	366_Y	1.093	0.92
40_L	110_K	1.088	0.92
96_L	441_H	1.086	0.92
312_L	328_I	1.081	0.92
29_Q	455_I	1.081	0.92
20_V	113_L	1.081	0.92
477_K	544_Q	1.079	0.92
11_I	34_L	1.079	0.92
132_E	148_R	1.076	0.92
479_R	520_Y	1.072	0.92
20_V	109_M	1.072	0.92
258_N	320_V	1.070	0.91
322_Q	326_A	1.069	0.91
252_H	256_D	1.066	0.91
52_V	61_V	1.066	0.91
255_I	280_I	1.065	0.91
552_E	556_Q	1.064	0.91
248_S	252_H	1.062	0.91
569_I	575_Y	1.061	0.91
446_L	473_I	1.058	0.91
102_K	300_E	1.057	0.91
244_L	294_Q	1.055	0.91
597_V	611_I	1.054	0.91
136_C	364_N	1.053	0.91
36_L	122_L	1.053	0.91
94_R	539_E	1.052	0.91
162_G	180_P	1.050	0.91
572_R	593_R	1.048	0.91
211_I	297_L	1.046	0.90
565_E	602_R	1.046	0.90
231_E	461_E	1.045	0.90
186_E	189_E	1.041	0.90
312_L	325_L	1.039	0.90
35_V	113_L	1.039	0.90
103_F	107_H	1.036	0.90
70_E	73_R	1.036	0.90
464_A	467_E	1.035	0.90
468_K	471_A	1.035	0.90
58_G	228_F	1.033	0.90
406_S	562_K	1.033	0.90
561_L	598_A	1.028	0.90
154_M	188_L	1.022	0.89
26_S	31_A	1.022	0.89
565_E	598_A	1.020	0.89
127_E	142_Q	1.016	0.89
139_V	152_V	1.014	0.89
208_S	305_Q	1.012	0.89
586_R	590_K	1.003	0.89
41_D	123_Q	1.001	0.88
131_V	187_H	0.995	0.88
477_K	481_H	0.992	0.88
130_I	137_R	0.991	0.88
494_Y	498_L	0.988	0.88
389_I	457_L	0.983	0.88
10_V	395_A	0.978	0.87
10_V	151_A	0.976	0.87
68_G	73_R	0.972	0.87
159_Y	175_P	0.970	0.87
36_L	124_G	0.967	0.87
433_A	439_L	0.966	0.87
129_L	149_A	0.965	0.87
398_K	454_R	0.958	0.86
366_Y	395_A	0.956	0.86
114_E	121_L	0.956	0.86
40_L	114_E	0.953	0.86
322_Q	335_Q	0.951	0.86
322_Q	325_L	0.948	0.86
206_V	331_L	0.946	0.85
127_E	183_K	0.945	0.85
301_G	304_T	0.945	0.85
476_E	530_E	0.943	0.85
32_K	120_T	0.942	0.85
599_Q	602_R	0.938	0.85
315_S	342_A	0.934	0.85
130_I	140_I	0.928	0.84
64_I	71_M	0.928	0.84
312_L	324_M	0.927	0.84
130_I	148_R	0.926	0.84
582_A	585_A	0.925	0.84
422_T	588_K	0.917	0.84
569_I	618_L	0.916	0.84
175_P	178_Q	0.915	0.83
168_D	260_H	0.914	0.83
198_F	347_A	0.913	0.83
295_I	312_L	0.913	0.83
29_Q	457_L	0.913	0.83
410_I	414_I	0.912	0.83
141_T	147_Y	0.911	0.83
55_P	95_A	0.907	0.83
6_G	32_K	0.902	0.83
193_F	348_I	0.901	0.83
194_D	361_K	0.900	0.82
52_V	75_I	0.899	0.82
393_R	455_I	0.897	0.82
193_F	367_T	0.895	0.82
136_C	363_T	0.895	0.82
150_K	395_A	0.895	0.82
245_T	295_I	0.895	0.82
554_S	557_Q	0.894	0.82
161_R	195_L	0.893	0.82
211_I	331_L	0.893	0.82
15_A	35_V	0.888	0.82
137_R	148_R	0.887	0.82
165_I	268_M	0.887	0.82
182_I	185_S	0.885	0.81
288_N	292_R	0.884	0.81
484_I	506_G	0.884	0.81
452_G	460_D	0.881	0.81
318_E	322_Q	0.880	0.81
261_R	320_V	0.879	0.81
120_T	335_Q	0.876	0.81
82_M	429_L	0.876	0.81
216_T	331_L	0.875	0.81
518_M	522_T	0.872	0.80
195_L	348_I	0.872	0.80
601_S	611_I	0.869	0.80
445_D	449_T	0.867	0.80
324_M	327_T	0.867	0.80
20_V	74_N	0.866	0.80
592_V	603_I	0.865	0.80
452_G	457_L	0.863	0.80
580_G	586_R	0.863	0.80
170_S	268_M	0.860	0.79
453_H	459_S	0.859	0.79
480_L	509_G	0.858	0.79
453_H	467_E	0.855	0.79
571_D	593_R	0.852	0.79
450_E	453_H	0.851	0.79
216_T	328_I	0.849	0.79
55_P	429_L	0.847	0.78
125_I	183_K	0.847	0.78
36_L	139_V	0.847	0.78
495_I	500_G	0.846	0.78
24_L	113_L	0.844	0.78
221_G	239_Q	0.844	0.78
607_N	610_D	0.843	0.78
111_N	115_K	0.841	0.78
122_L	147_Y	0.840	0.78
422_T	604_S	0.840	0.78
137_R	363_T	0.838	0.78
207_K	337_M	0.837	0.78
125_I	142_Q	0.836	0.78
153_V	389_I	0.836	0.78
612_S	616_V	0.836	0.78
494_Y	497_S	0.832	0.77
522_T	525_K	0.831	0.77
260_H	263_P	0.830	0.77
326_A	335_Q	0.830	0.77
11_I	147_Y	0.827	0.77
572_R	621_G	0.827	0.77
354_W	571_D	0.826	0.77
520_Y	538_A	0.825	0.77
389_I	393_R	0.824	0.77
78_T	100_A	0.820	0.76
406_S	561_L	0.817	0.76
322_Q	339_A	0.816	0.76
450_E	467_E	0.816	0.76
104_Q	108_E	0.814	0.76
396_L	454_R	0.812	0.75
336_M	339_A	0.811	0.75
129_L	152_V	0.806	0.75
326_A	333_N	0.805	0.75
56_A	59_I	0.805	0.75
350_P	422_T	0.803	0.75
389_I	401_V	0.802	0.75
474_E	477_K	0.801	0.74
386_M	401_V	0.799	0.74
150_K	364_N	0.798	0.74
60_V	413_L	0.797	0.74
472_A	475_A	0.797	0.74
59_I	95_A	0.795	0.74
193_F	362_I	0.793	0.74
348_I	352_Q	0.792	0.74
123_Q	306_E	0.791	0.74
84_M	96_L	0.791	0.74
131_V	137_R	0.789	0.73
138_G	152_V	0.789	0.73
33_T	116_E	0.787	0.73
206_V	309_V	0.787	0.73
513_M	545_V	0.787	0.73
354_W	363_T	0.786	0.73
266_S	285_V	0.785	0.73
45_F	176_N	0.779	0.72
138_G	149_A	0.778	0.72
168_D	266_S	0.777	0.72
579_K	586_R	0.776	0.72
250_E	257_S	0.775	0.72
592_V	599_Q	0.774	0.72
231_E	465_A	0.771	0.72
250_E	254_I	0.768	0.71
47_P	429_L	0.768	0.71
149_A	364_N	0.766	0.71
318_E	339_A	0.766	0.71
216_T	329_P	0.765	0.71
40_L	337_M	0.765	0.71
295_I	309_V	0.765	0.71
404_S	561_L	0.764	0.71
161_R	186_E	0.764	0.71
129_L	136_C	0.762	0.71
446_L	466_F	0.762	0.71
466_F	470_K	0.762	0.71
255_I	284_V	0.758	0.70
367_T	371_I	0.758	0.70
503_L	507_V	0.758	0.70
475_A	478_K	0.757	0.70
24_L	112_T	0.754	0.70
62_R	96_L	0.753	0.70
163_R	172_S	0.751	0.70
558_V	561_L	0.751	0.70
42_M	178_Q	0.750	0.70
288_N	291_P	0.749	0.69
243_W	307_V	0.748	0.69
477_K	541_V	0.748	0.69
25_A	457_L	0.748	0.69
382_G	428_L	0.747	0.69
108_E	112_T	0.747	0.69
129_L	138_G	0.747	0.69
210_T	335_Q	0.745	0.69
40_L	113_L	0.743	0.69
603_I	606_V	0.743	0.69
570_P	593_R	0.741	0.69
107_H	303_N	0.741	0.69
399_E	454_R	0.739	0.68
449_T	452_G	0.739	0.68
34_L	147_Y	0.738	0.68
73_R	112_T	0.735	0.68
110_K	337_M	0.735	0.68
115_K	305_Q	0.735	0.68
56_A	428_L	0.735	0.68
102_K	309_V	0.735	0.68
51_S	310_Q	0.733	0.68
68_G	462_R	0.732	0.68
12_V	26_S	0.732	0.68
559_E	563_K	0.731	0.68
542_E	546_K	0.729	0.67
137_R	150_K	0.727	0.67
204_P	340_G	0.726	0.67
404_S	598_A	0.725	0.67
137_R	140_I	0.725	0.67
477_K	545_V	0.725	0.67
134_G	363_T	0.725	0.67
498_L	518_M	0.724	0.67
224_V	535_Q	0.722	0.67
309_V	334_V	0.721	0.66
154_M	367_T	0.719	0.66
165_I	343_I	0.719	0.66
238_D	302_R	0.716	0.66
265_Y	282_D	0.716	0.66
435_Y	558_V	0.716	0.66
366_Y	393_R	0.716	0.66
168_D	268_M	0.715	0.66
11_I	139_V	0.715	0.66
419_T	599_Q	0.714	0.66
469_K	540_Q	0.714	0.66
165_I	170_S	0.714	0.66
29_Q	392_G	0.713	0.66
501_S	517_E	0.713	0.66
213_Y	243_W	0.710	0.65
62_R	441_H	0.710	0.65
486_K	506_G	0.710	0.65
96_L	310_Q	0.709	0.65
479_R	483_V	0.709	0.65
409_Y	433_A	0.709	0.65
252_H	284_V	0.709	0.65
521_E	535_Q	0.708	0.65
561_L	611_I	0.708	0.65
585_A	607_N	0.707	0.65
497_S	525_K	0.703	0.65
509_G	527_A	0.702	0.64
245_T	329_P	0.702	0.64
413_L	428_L	0.700	0.64
168_D	263_P	0.700	0.64
514_K	548_E	0.700	0.64
41_D	110_K	0.697	0.64
305_Q	337_M	0.696	0.64
13_I	156_T	0.695	0.64
209_D	335_Q	0.694	0.64
166_L	339_A	0.693	0.63
58_G	84_M	0.693	0.63
38_I	42_M	0.692	0.63
80_I	301_G	0.692	0.63
141_T	263_P	0.691	0.63
70_E	113_L	0.691	0.63
42_M	45_F	0.688	0.63
453_H	466_F	0.688	0.63
540_Q	544_Q	0.687	0.63
266_S	282_D	0.686	0.63
356_T	401_V	0.685	0.63
556_Q	559_E	0.685	0.63
429_L	607_N	0.685	0.63
142_Q	179_Q	0.685	0.63
11_I	126_V	0.684	0.62
68_G	457_L	0.682	0.62
357_L	414_I	0.682	0.62
47_P	55_P	0.681	0.62
140_I	187_H	0.681	0.62
44_A	102_K	0.681	0.62
420_K	604_S	0.680	0.62
175_P	343_I	0.678	0.62
359_T	362_I	0.677	0.62
87_T	94_R	0.677	0.62
78_T	98_A	0.676	0.61
15_A	109_M	0.676	0.61
349_V	352_Q	0.675	0.61
217_E	292_R	0.675	0.61
282_D	315_S	0.675	0.61
10_V	31_A	0.674	0.61
208_S	243_W	0.673	0.61
250_E	329_P	0.671	0.61
530_E	533_V	0.671	0.61
264_M	319_D	0.670	0.61
136_C	152_V	0.670	0.61
325_L	340_G	0.670	0.61
408_A	412_V	0.668	0.61
487_P	503_L	0.666	0.60
382_G	410_I	0.666	0.60
450_E	466_F	0.665	0.60
252_H	292_R	0.665	0.60
59_I	428_L	0.665	0.60
355_P	419_T	0.665	0.60
75_I	228_F	0.664	0.60
360_K	592_V	0.664	0.60
323_R	326_A	0.663	0.60
323_R	327_T	0.663	0.60
309_V	610_D	0.662	0.60
485_I	493_E	0.661	0.60
446_L	450_E	0.659	0.60
489_P	493_E	0.659	0.60
62_R	84_M	0.659	0.60
489_P	492_Q	0.659	0.60
319_D	323_R	0.658	0.59
192_G	352_Q	0.657	0.59
306_E	338_R	0.657	0.59
513_M	523_V	0.656	0.59
77_K	111_N	0.656	0.59
489_P	506_G	0.656	0.59
64_I	382_G	0.655	0.59
74_N	100_A	0.655	0.59
572_R	618_L	0.654	0.59
280_I	314_T	0.652	0.59
81_Q	239_Q	0.651	0.59
83_R	219_Q	0.650	0.58
261_R	317_P	0.650	0.58
317_P	320_V	0.649	0.58
220_P	223_D	0.647	0.58
399_E	568_K	0.646	0.58
160_L	181_S	0.645	0.58
413_L	588_K	0.645	0.58
82_M	98_A	0.644	0.58
512_L	518_M	0.644	0.58
111_N	303_N	0.643	0.58
104_Q	302_R	0.643	0.58
518_M	523_V	0.641	0.57
28_R	116_E	0.641	0.57
252_H	288_N	0.639	0.57
159_Y	162_G	0.639	0.57
242_C	299_P	0.639	0.57
255_I	324_M	0.639	0.57
247_T	280_I	0.638	0.57
110_K	123_Q	0.638	0.57
127_E	140_I	0.638	0.57
582_A	607_N	0.638	0.57
372_N	383_Q	0.638	0.57
175_P	429_L	0.637	0.57
458_I	466_F	0.637	0.57
533_V	538_A	0.637	0.57
493_E	496_R	0.636	0.57
266_S	271_G	0.636	0.57
349_V	421_G	0.634	0.57
248_S	327_T	0.634	0.57
24_L	74_N	0.634	0.57
194_D	591_N	0.633	0.56
110_K	207_K	0.632	0.56
359_T	371_I	0.632	0.56
367_T	429_L	0.631	0.56
164_I	343_I	0.631	0.56
246_Y	291_P	0.631	0.56
10_V	153_V	0.629	0.56
359_T	367_T	0.628	0.56
388_G	391_A	0.626	0.56
492_Q	495_I	0.625	0.56
15_A	44_A	0.625	0.56
309_V	312_L	0.625	0.56
359_T	363_T	0.624	0.55
258_N	265_Y	0.624	0.55
47_P	82_M	0.621	0.55
513_M	518_M	0.620	0.55
271_G	382_G	0.619	0.55
159_Y	178_Q	0.619	0.55
471_A	474_E	0.619	0.55
258_N	316_L	0.619	0.55
579_K	613_I	0.618	0.55
508_R	581_I	0.617	0.55
533_V	537_V	0.616	0.54
45_F	123_Q	0.616	0.54
199_K	313_S	0.615	0.54
155_T	347_A	0.615	0.54
47_P	175_P	0.614	0.54
464_A	475_A	0.613	0.54
453_H	458_I	0.612	0.54
474_E	481_H	0.612	0.54
187_H	362_I	0.612	0.54
351_T	421_G	0.611	0.54
215_K	330_G	0.611	0.54
70_E	116_E	0.609	0.54
450_E	463_Y	0.609	0.54
258_N	324_M	0.608	0.54
130_I	152_V	0.608	0.54
94_R	441_H	0.607	0.53
98_A	228_F	0.607	0.53
251_T	254_I	0.606	0.53
268_M	271_G	0.606	0.53
47_P	310_Q	0.605	0.53
259_L	266_S	0.605	0.53
55_P	82_M	0.604	0.53
479_R	530_E	0.604	0.53
263_P	268_M	0.604	0.53
51_S	55_P	0.602	0.53
153_V	392_G	0.601	0.53
569_I	576_D	0.601	0.53
493_E	497_S	0.601	0.53
408_A	422_T	0.600	0.53
79_H	225_P	0.599	0.52
261_R	323_R	0.599	0.52
612_S	615_L	0.598	0.52
264_M	315_S	0.598	0.52
487_P	506_G	0.598	0.52
26_S	151_A	0.597	0.52
168_D	319_D	0.597	0.52
23_A	35_V	0.596	0.52
327_T	334_V	0.596	0.52
476_E	480_L	0.595	0.52
47_P	159_Y	0.595	0.52
82_M	96_L	0.595	0.52
256_D	284_V	0.594	0.52
123_Q	338_R	0.593	0.52
257_S	260_H	0.592	0.52
187_H	195_L	0.591	0.51
38_I	181_S	0.590	0.51
127_E	144_G	0.590	0.51
328_I	332_E	0.590	0.51
13_I	152_V	0.590	0.51
237_T	302_R	0.589	0.51
227_A	428_L	0.588	0.51
578_I	581_I	0.588	0.51
45_F	102_K	0.588	0.51
51_S	80_I	0.588	0.51
165_I	429_L	0.587	0.51
214_S	333_N	0.585	0.51
435_Y	554_S	0.585	0.51
44_A	109_M	0.584	0.51
47_P	96_L	0.583	0.51
511_D	514_K	0.583	0.51
348_I	597_V	0.583	0.51
26_S	34_L	0.582	0.50
535_Q	539_E	0.582	0.50
422_T	438_L	0.582	0.50
199_K	269_I	0.581	0.50
274_P	313_S	0.580	0.50
442_D	540_Q	0.580	0.50
284_V	314_T	0.579	0.50
324_M	328_I	0.579	0.50
467_E	471_A	0.579	0.50
323_R	329_P	0.577	0.50
403_L	455_I	0.577	0.50
533_V	541_V	0.577	0.50
261_R	264_M	0.576	0.50
165_I	310_Q	0.575	0.50
175_P	347_A	0.575	0.50
520_Y	533_V	0.575	0.50
235_Y	238_D	0.575	0.50
219_Q	242_C	0.572	0.49
537_V	540_Q	0.572	0.49
520_Y	531_V	0.572	0.49
129_L	154_M	0.571	0.49
207_K	304_T	0.571	0.49
163_R	173_S	0.570	0.49
472_A	541_V	0.569	0.49
26_S	30_G	0.569	0.49
13_I	603_I	0.568	0.49
95_A	429_L	0.568	0.49
129_L	187_H	0.568	0.49
55_P	58_G	0.568	0.49
488_S	492_Q	0.568	0.49
132_E	146_H	0.567	0.49
159_Y	429_L	0.567	0.49
15_A	43_V	0.567	0.49
245_T	328_I	0.567	0.49
163_R	270_K	0.566	0.48
315_S	319_D	0.566	0.48
504_K	507_V	0.565	0.48
185_S	189_E	0.565	0.48
382_G	385_I	0.565	0.48
163_R	181_S	0.565	0.48
527_A	530_E	0.565	0.48
401_V	454_R	0.563	0.48
395_A	398_K	0.563	0.48
461_E	464_A	0.563	0.48
11_I	129_L	0.562	0.48
388_G	392_G	0.561	0.48
267_G	342_A	0.560	0.48
166_L	169_L	0.559	0.48
267_G	282_D	0.559	0.48
55_P	96_L	0.559	0.48
348_I	359_T	0.558	0.47
130_I	149_A	0.558	0.47
318_E	336_M	0.556	0.47
109_M	113_L	0.556	0.47
225_P	235_Y	0.556	0.47
122_L	335_Q	0.555	0.47
29_Q	386_M	0.555	0.47
487_P	495_I	0.554	0.47
183_K	188_L	0.554	0.47
175_P	310_Q	0.552	0.47
258_N	323_R	0.550	0.47
136_C	149_A	0.549	0.46
15_A	121_L	0.549	0.46
112_T	115_K	0.548	0.46
201_G	313_S	0.547	0.46
492_Q	503_L	0.547	0.46
503_L	506_G	0.546	0.46
315_S	550_Y	0.545	0.46
520_Y	542_E	0.545	0.46
141_T	145_A	0.545	0.46
6_G	145_A	0.544	0.46
429_L	441_H	0.544	0.46
257_S	320_V	0.544	0.46
20_V	23_A	0.544	0.46
568_K	596_S	0.544	0.46
45_F	106_Q	0.543	0.46
231_E	459_S	0.543	0.46
567_K	618_L	0.543	0.46
51_S	297_L	0.543	0.46
217_E	244_L	0.543	0.46
117_P	209_D	0.542	0.46
355_P	402_I	0.541	0.45
104_Q	303_N	0.541	0.45
579_K	617_Y	0.540	0.45
280_I	296_F	0.538	0.45
56_A	95_A	0.538	0.45
191_L	362_I	0.538	0.45
56_A	375_S	0.536	0.45
264_M	342_A	0.536	0.45
310_Q	429_L	0.536	0.45
503_L	515_R	0.536	0.45
497_S	502_E	0.536	0.45
258_N	266_S	0.535	0.45
399_E	471_A	0.534	0.45
203_P	313_S	0.534	0.45
71_M	105_Y	0.534	0.45
403_L	407_D	0.534	0.45
209_D	304_T	0.533	0.45
163_R	271_G	0.533	0.45
309_V	325_L	0.533	0.45
544_Q	548_E	0.533	0.45
510_T	514_K	0.533	0.45
569_I	621_G	0.532	0.44
60_V	155_T	0.532	0.44
79_H	429_L	0.530	0.44
156_T	348_I	0.530	0.44
170_S	262_S	0.530	0.44
509_G	518_M	0.530	0.44
138_G	146_H	0.529	0.44
181_S	187_H	0.527	0.44
66_A	445_D	0.527	0.44
435_Y	553_K	0.526	0.44
296_F	314_T	0.526	0.44
273_G	313_S	0.525	0.44
47_P	198_F	0.525	0.44
254_I	323_R	0.525	0.44
458_I	462_R	0.524	0.43
6_G	120_T	0.524	0.43
413_L	604_S	0.524	0.43
55_P	94_R	0.524	0.43
435_Y	565_E	0.524	0.43
25_A	28_R	0.524	0.43
59_I	409_Y	0.523	0.43
45_F	178_Q	0.523	0.43
575_Y	590_K	0.523	0.43
9_D	32_K	0.523	0.43
505_D	511_D	0.523	0.43
181_S	189_E	0.523	0.43
285_V	431_S	0.523	0.43
135_E	394_K	0.522	0.43
356_T	396_L	0.522	0.43
82_M	165_I	0.522	0.43
164_I	171_Y	0.522	0.43
126_V	139_V	0.522	0.43
73_R	77_K	0.522	0.43
414_I	498_L	0.521	0.43
326_A	336_M	0.520	0.43
310_Q	328_I	0.520	0.43
577_A	621_G	0.520	0.43
488_S	495_I	0.519	0.43
347_A	429_L	0.519	0.43
280_I	316_L	0.519	0.43
360_K	599_Q	0.518	0.43
134_G	137_R	0.517	0.43
461_E	465_A	0.517	0.43
294_Q	439_L	0.517	0.43
357_L	386_M	0.516	0.42
47_P	347_A	0.516	0.42
442_D	543_I	0.516	0.42
143_T	318_E	0.515	0.42
58_G	88_G	0.515	0.42
320_V	323_R	0.514	0.42
422_T	603_I	0.514	0.42
264_M	269_I	0.514	0.42
245_T	309_V	0.514	0.42
566_N	578_I	0.513	0.42
150_K	454_R	0.513	0.42
109_M	112_T	0.512	0.42
259_L	324_M	0.512	0.42
255_I	316_L	0.512	0.42
173_S	553_K	0.511	0.42
272_T	587_Q	0.510	0.42
487_P	505_D	0.510	0.42
13_I	23_A	0.510	0.42
473_I	544_Q	0.510	0.42
250_E	471_A	0.509	0.42
264_M	282_D	0.509	0.42
162_G	542_E	0.509	0.42
451_I	455_I	0.508	0.42
510_T	548_E	0.508	0.42
129_L	146_H	0.508	0.42
389_I	455_I	0.506	0.41
137_R	149_A	0.506	0.41
102_K	216_T	0.506	0.41
162_G	166_L	0.505	0.41
441_H	607_N	0.505	0.41
282_D	296_F	0.504	0.41
479_R	533_V	0.504	0.41
258_N	319_D	0.504	0.41
246_Y	288_N	0.504	0.41
286_R	583_T	0.504	0.41
103_F	106_Q	0.504	0.41
446_L	469_K	0.504	0.41
149_A	523_V	0.504	0.41
105_Y	109_M	0.504	0.41
490_E	495_I	0.503	0.41
274_P	375_S	0.502	0.41
288_N	413_L	0.502	0.41
91_P	442_D	0.502	0.41
536_D	568_K	0.501	0.41
262_S	315_S	0.501	0.41
262_S	268_M	0.501	0.41
282_D	342_A	0.501	0.41
71_M	75_I	0.501	0.41
529_P	532_P	0.501	0.41
606_V	609_A	0.500	0.41
423_N	588_K	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3cesA	2	0.828	100	0.365	Contact Map
3cp8A	2	0.9586	100	0.372	Contact Map
2zxiA	2	0.949	100	0.401	Contact Map
3g5sA	1	0.6162	100	0.724	Contact Map
2culA	1	0.3535	100	0.88	Contact Map
3v76A	2	0.5318	100	0.892	Contact Map
3nlcA	1	0.5844	100	0.894	Contact Map
4cnkA	2	0.5414	100	0.908	Contact Map
2i0zA	1	0.5541	99.8	0.931	Contact Map
3gyxA	2	0.7707	99.7	0.938	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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