MNME - BACSU - GREMLIN Contacts

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MNME - tRNA modification GTPase MnmE

UniProt:	P25811	Sequences: MDTIAAISTPMGEGAIAIVRLSGPEAIQIADKIYKGPKGKTLSSVESHTIHYGHIVDRPSDRVVEEVMVSVLKAPRTFTREDVIEINCHGGIVTVNQVLQLALREGARLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAMNQMEGRLSALVRRLRSEILETLAHVEVNIDYPEYDDVEEMTHQILVEKATAVKKEIETLLRTSEQGKILREGLSTVIIGRPNVGKSSLLNSLVHEAKAIVTDIPGTTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSRQVLKEADLILLVLNYSEELSEEDVKLFEAVEGMDVIVILNKTDLEPKIDTERVRELANGRPVVTTSLLKEEGINDLEEAIQSLFYTGAIESGDLTYVSNTRHITILQQAKRAIEDALSGIEQDVPIDMVQIDLTRCWELLGEIIGDSVHESLIDQLFSQFCLGK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	459 (442)
Sequences:	4718 (3527)
Seq/√Len:	167.8

ECOLI - MNME
BACSU - MNME

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
50_I	70_S	4.741	1.00
17_A	95_V	4.032	1.00
289_I	292_E	4.017	1.00
25_E	28_Q	3.788	1.00
29_I	107_A	3.402	1.00
78_F	116_T	3.166	1.00
251_D	285_I	3.127	1.00
128_S	157_S	3.030	1.00
5_A	99_L	3.015	1.00
240_S	368_I	2.997	1.00
267_R	376_Q	2.859	1.00
46_E	49_T	2.853	1.00
21_L	30_A	2.691	1.00
305_L	375_I	2.686	1.00
367_G	370_D	2.634	1.00
374_A	377_S	2.614	1.00
206_E	405_K	2.598	1.00
180_Y	457_L	2.565	1.00
335_N	362_L	2.537	1.00
305_L	333_I	2.490	1.00
356_P	374_A	2.405	1.00
5_A	102_A	2.376	1.00
202_K	405_K	2.343	1.00
35_K	56_V	2.318	1.00
307_V	335_N	2.283	1.00
27_I	71_V	2.268	1.00
70_S	87_N	2.267	1.00
202_K	409_E	2.262	1.00
252_I	284_D	2.251	1.00
80_R	124_R	2.238	1.00
21_L	102_A	2.172	1.00
195_V	416_E	2.164	1.00
10_P	14_G	2.158	1.00
52_Y	66_E	2.133	1.00
58_R	61_D	2.120	1.00
199_T	412_L	2.099	1.00
310_Y	334_L	2.096	1.00
205_I	401_L	2.091	1.00
62_R	146_N	2.076	1.00
227_I	298_L	2.059	1.00
34_Y	53_G	2.049	1.00
222_L	379_F	2.049	1.00
101_L	105_E	2.033	1.00
282_T	291_V	2.031	1.00
296_Q	300_E	2.017	1.00
399_T	403_Q	2.015	1.00
202_K	412_L	1.987	1.00
3_T	25_E	1.954	1.00
259_V	274_V	1.940	1.00
240_S	365_E	1.904	1.00
333_I	358_V	1.890	1.00
116_T	133_V	1.887	1.00
166_E	197_K	1.877	1.00
161_R	441_D	1.873	1.00
3_T	26_A	1.857	1.00
26_A	84_I	1.828	1.00
18_I	87_N	1.824	1.00
450_Q	454_Q	1.814	1.00
405_K	409_E	1.813	1.00
295_R	324_A	1.786	1.00
166_E	204_E	1.768	1.00
111_E	117_K	1.753	1.00
136_L	145_M	1.750	1.00
292_E	296_Q	1.743	1.00
316_E	319_V	1.732	1.00
78_F	133_V	1.726	1.00
50_I	68_M	1.713	1.00
159_L	204_E	1.703	1.00
54_H	63_V	1.701	1.00
134_M	138_R	1.683	1.00
187_E	190_T	1.674	1.00
68_M	72_L	1.670	1.00
225_V	301_A	1.657	1.00
67_V	86_I	1.650	1.00
303_L	375_I	1.649	1.00
202_K	408_I	1.647	1.00
166_E	200_A	1.643	1.00
32_K	105_E	1.639	1.00
403_Q	437_E	1.616	1.00
319_V	323_E	1.614	1.00
195_V	412_L	1.604	1.00
337_T	359_T	1.600	1.00
373_E	377_S	1.599	1.00
269_V	380_Y	1.586	1.00
164_R	168_L	1.584	1.00
55_I	67_V	1.584	1.00
77_T	80_R	1.584	1.00
288_R	292_E	1.584	1.00
145_M	149_M	1.576	1.00
407_A	430_R	1.576	1.00
246_K	262_E	1.575	1.00
142_D	145_M	1.563	1.00
250_T	286_V	1.547	1.00
206_E	210_R	1.531	1.00
26_A	30_A	1.527	1.00
238_L	247_A	1.525	1.00
285_I	288_R	1.523	1.00
403_Q	434_L	1.496	1.00
93_V	145_M	1.485	1.00
7_I	95_V	1.467	1.00
407_A	427_D	1.459	1.00
103_L	109_L	1.457	1.00
21_L	86_I	1.455	1.00
206_E	409_E	1.453	1.00
224_T	271_L	1.446	1.00
310_Y	337_T	1.437	1.00
117_K	121_L	1.435	1.00
309_N	312_E	1.429	1.00
172_A	450_Q	1.408	1.00
243_H	372_E	1.408	1.00
57_D	62_R	1.398	1.00
223_S	272_R	1.396	1.00
259_V	297_V	1.380	1.00
202_K	206_E	1.380	1.00
30_A	84_I	1.377	1.00
413_S	417_Q	1.370	1.00
242_V	246_K	1.370	1.00
337_T	366_E	1.364	1.00
58_R	101_L	1.359	1.00
157_S	161_R	1.354	1.00
45_V	71_V	1.350	1.00
3_T	29_I	1.348	1.00
411_A	424_V	1.340	1.00
74_A	82_D	1.338	1.00
434_L	437_E	1.335	1.00
334_L	359_T	1.327	1.00
331_I	374_A	1.322	1.00
230_P	253_P	1.321	1.00
267_R	373_E	1.311	1.00
398_I	402_Q	1.309	1.00
410_D	413_S	1.297	1.00
297_V	300_E	1.296	1.00
310_Y	340_E	1.292	1.00
410_D	427_D	1.287	1.00
198_A	408_I	1.283	1.00
414_G	427_D	1.281	1.00
161_R	165_S	1.278	1.00
135_D	219_R	1.277	1.00
56_V	63_V	1.274	1.00
75_P	82_D	1.272	1.00
165_S	450_Q	1.267	1.00
409_E	412_L	1.264	1.00
334_L	357_V	1.264	1.00
187_E	191_H	1.246	1.00
125_I	133_V	1.244	1.00
176_V	180_Y	1.242	1.00
308_L	332_V	1.242	1.00
265_N	268_G	1.241	1.00
252_I	285_I	1.236	1.00
236_S	362_L	1.235	1.00
396_R	400_I	1.231	1.00
392_V	401_L	1.229	1.00
358_V	374_A	1.225	1.00
240_S	362_L	1.224	1.00
5_A	103_L	1.223	1.00
165_S	169_E	1.220	1.00
293_R	297_V	1.217	1.00
296_Q	299_K	1.213	1.00
47_S	73_K	1.213	1.00
178_I	183_Y	1.210	1.00
400_I	434_L	1.210	1.00
263_Y	270_P	1.207	1.00
286_V	289_I	1.203	1.00
229_R	315_S	1.201	1.00
27_I	73_K	1.193	1.00
141_T	265_N	1.192	1.00
364_K	367_G	1.184	1.00
395_T	399_T	1.182	1.00
303_L	331_I	1.182	1.00
126_D	130_A	1.181	1.00
282_T	285_I	1.181	1.00
331_I	375_I	1.180	1.00
265_N	270_P	1.180	1.00
30_A	69_V	1.168	1.00
263_Y	272_R	1.162	1.00
47_S	71_V	1.159	1.00
102_A	107_A	1.158	1.00
26_A	29_I	1.154	1.00
74_A	80_R	1.150	1.00
127_L	131_E	1.146	1.00
73_K	82_D	1.144	1.00
64_V	101_L	1.141	1.00
101_L	104_R	1.141	1.00
28_Q	32_K	1.141	1.00
312_E	315_S	1.138	1.00
133_V	137_I	1.137	1.00
62_R	97_Q	1.122	1.00
394_N	397_H	1.116	1.00
57_D	104_R	1.113	1.00
407_A	410_D	1.107	1.00
7_I	17_A	1.106	1.00
72_L	77_T	1.102	1.00
132_A	136_L	1.101	1.00
97_Q	142_D	1.100	1.00
67_V	70_S	1.097	1.00
28_Q	31_D	1.095	1.00
248_I	289_I	1.091	1.00
142_D	146_N	1.089	1.00
86_I	98_V	1.087	1.00
108_R	111_E	1.086	1.00
229_R	318_D	1.083	1.00
147_V	151_Q	1.083	1.00
45_V	51_H	1.082	1.00
317_E	320_K	1.082	1.00
325_V	330_V	1.081	1.00
162_R	166_E	1.079	1.00
36_G	53_G	1.077	1.00
131_E	396_R	1.072	1.00
229_R	317_E	1.067	1.00
5_A	21_L	1.063	0.99
29_I	102_A	1.061	0.99
158_A	162_R	1.061	0.99
15_A	83_V	1.060	0.99
130_A	133_V	1.055	0.99
447_L	451_L	1.054	0.99
93_V	97_Q	1.051	0.99
399_T	402_Q	1.050	0.99
179_D	182_E	1.044	0.99
180_Y	183_Y	1.043	0.99
141_T	144_A	1.038	0.99
311_S	339_L	1.038	0.99
271_L	375_I	1.037	0.99
57_D	101_L	1.030	0.99
3_T	24_P	1.029	0.99
125_I	129_Q	1.028	0.99
310_Y	341_P	1.022	0.99
316_E	320_K	1.019	0.99
80_R	125_I	1.018	0.99
224_T	273_L	1.017	0.99
95_V	98_V	1.017	0.99
88_C	98_V	1.012	0.99
306_L	332_V	1.006	0.99
175_E	429_T	1.005	0.99
7_I	99_L	1.003	0.99
151_Q	393_S	1.001	0.99
224_T	303_L	1.000	0.99
120_F	127_L	0.992	0.99
395_T	398_I	0.986	0.99
129_Q	133_V	0.986	0.99
15_A	18_I	0.986	0.99
115_F	119_A	0.985	0.99
190_T	193_I	0.984	0.99
143_R	146_N	0.981	0.99
436_G	440_G	0.979	0.99
120_F	124_R	0.979	0.99
241_L	368_I	0.977	0.99
116_T	120_F	0.971	0.99
171_L	432_W	0.963	0.99
123_G	127_L	0.962	0.99
129_Q	132_A	0.961	0.99
148_A	152_M	0.959	0.99
185_D	190_T	0.958	0.99
406_R	410_D	0.958	0.99
374_A	378_L	0.956	0.99
110_A	114_E	0.951	0.99
289_I	293_R	0.949	0.99
285_I	289_I	0.948	0.99
175_E	182_E	0.945	0.99
137_I	141_T	0.944	0.99
198_A	411_A	0.943	0.99
33_I	102_A	0.941	0.99
436_G	442_S	0.938	0.99
261_E	297_V	0.931	0.99
390_T	393_S	0.926	0.99
100_Q	395_T	0.926	0.99
160_V	435_L	0.911	0.98
193_I	197_K	0.911	0.98
56_V	61_D	0.910	0.98
150_N	155_R	0.909	0.98
8_S	16_I	0.908	0.98
360_T	363_L	0.895	0.98
131_E	135_D	0.891	0.98
175_E	179_D	0.891	0.98
229_R	232_V	0.891	0.98
282_T	288_R	0.887	0.98
236_S	360_T	0.884	0.98
216_K	244_E	0.884	0.98
175_E	178_I	0.883	0.98
183_Y	186_V	0.883	0.98
185_D	189_M	0.882	0.98
320_K	324_A	0.882	0.98
242_V	262_E	0.876	0.98
140_K	144_A	0.873	0.98
298_L	304_I	0.870	0.98
115_F	118_R	0.868	0.98
426_I	432_W	0.868	0.98
19_V	99_L	0.867	0.98
100_Q	142_D	0.866	0.98
203_K	206_E	0.866	0.98
27_I	31_D	0.865	0.98
37_P	45_V	0.864	0.98
179_D	186_V	0.857	0.98
405_K	408_I	0.848	0.97
90_G	94_T	0.848	0.97
333_I	371_L	0.847	0.97
128_S	132_A	0.847	0.97
159_L	163_L	0.846	0.97
97_Q	101_L	0.843	0.97
155_R	159_L	0.843	0.97
113_G	116_T	0.843	0.97
124_R	128_S	0.842	0.97
205_I	404_A	0.842	0.97
98_V	102_A	0.841	0.97
123_G	126_D	0.839	0.97
209_L	402_Q	0.830	0.97
205_I	408_I	0.829	0.97
264_V	273_L	0.826	0.97
162_R	204_E	0.826	0.97
274_V	297_V	0.825	0.97
174_V	425_Q	0.824	0.97
169_E	454_Q	0.821	0.97
122_N	126_D	0.819	0.97
115_F	137_I	0.816	0.97
124_R	127_L	0.816	0.97
91_G	98_V	0.814	0.97
91_G	95_V	0.814	0.97
195_V	199_T	0.809	0.97
223_S	297_V	0.809	0.97
118_R	122_N	0.808	0.97
175_E	451_L	0.807	0.97
196_E	199_T	0.806	0.97
155_R	158_A	0.806	0.97
108_R	113_G	0.805	0.97
130_A	134_M	0.803	0.96
114_E	118_R	0.803	0.96
252_I	286_V	0.802	0.96
333_I	360_T	0.801	0.96
80_R	122_N	0.801	0.96
406_R	409_E	0.800	0.96
136_L	149_M	0.800	0.96
320_K	323_E	0.800	0.96
410_D	430_R	0.798	0.96
126_D	154_G	0.795	0.96
25_E	29_I	0.791	0.96
223_S	300_E	0.790	0.96
173_H	177_N	0.790	0.96
266_V	372_E	0.789	0.96
306_L	322_F	0.789	0.96
193_I	196_E	0.789	0.96
154_G	157_S	0.788	0.96
323_E	453_S	0.787	0.96
411_A	428_L	0.784	0.96
173_H	176_V	0.782	0.96
237_L	307_V	0.782	0.96
135_D	394_N	0.782	0.96
409_E	413_S	0.782	0.96
393_S	397_H	0.780	0.96
371_L	375_I	0.780	0.96
114_E	119_A	0.779	0.96
146_N	150_N	0.779	0.96
271_L	379_F	0.778	0.96
72_L	83_V	0.776	0.96
141_T	148_A	0.776	0.96
108_R	112_P	0.775	0.96
199_T	202_K	0.770	0.96
113_G	118_R	0.770	0.96
238_L	260_I	0.770	0.96
407_A	434_L	0.767	0.95
370_D	374_A	0.765	0.95
91_G	96_N	0.765	0.95
260_I	294_S	0.764	0.95
141_T	149_M	0.764	0.95
158_A	161_R	0.762	0.95
48_H	51_H	0.762	0.95
135_D	139_A	0.761	0.95
163_L	201_V	0.760	0.95
71_V	74_A	0.760	0.95
308_L	334_L	0.759	0.95
26_A	83_V	0.758	0.95
85_E	90_G	0.755	0.95
307_V	360_T	0.754	0.95
133_V	136_L	0.753	0.95
197_K	200_A	0.753	0.95
120_F	126_D	0.752	0.95
331_I	358_V	0.750	0.95
96_N	100_Q	0.750	0.95
186_V	193_I	0.748	0.95
169_E	450_Q	0.746	0.95
412_L	416_E	0.744	0.95
33_I	36_G	0.741	0.95
67_V	88_C	0.741	0.95
113_G	126_D	0.739	0.94
401_L	404_A	0.737	0.94
187_E	192_Q	0.737	0.94
110_A	118_R	0.735	0.94
177_N	181_P	0.734	0.94
189_M	192_Q	0.732	0.94
238_L	246_K	0.731	0.94
323_E	326_E	0.731	0.94
113_G	117_K	0.728	0.94
109_L	113_G	0.726	0.94
261_E	272_R	0.725	0.94
69_V	86_I	0.721	0.94
123_G	131_E	0.720	0.94
308_L	343_I	0.720	0.94
11_M	14_G	0.719	0.94
229_R	312_E	0.719	0.94
294_S	297_V	0.718	0.94
19_V	98_V	0.716	0.93
116_T	130_A	0.716	0.93
27_I	30_A	0.715	0.93
144_A	148_A	0.715	0.93
125_I	130_A	0.710	0.93
151_Q	156_L	0.708	0.93
31_D	45_V	0.708	0.93
21_L	26_A	0.706	0.93
131_E	139_A	0.705	0.93
363_L	366_E	0.704	0.93
408_I	431_C	0.703	0.93
369_N	372_E	0.703	0.93
196_E	200_A	0.703	0.93
120_F	137_I	0.703	0.93
410_D	414_G	0.702	0.93
90_G	99_L	0.701	0.93
241_L	372_E	0.695	0.92
58_R	104_R	0.690	0.92
151_Q	397_H	0.689	0.92
16_I	68_M	0.685	0.92
426_I	429_T	0.684	0.92
127_L	135_D	0.683	0.92
130_A	137_I	0.679	0.92
366_E	370_D	0.678	0.92
164_R	432_W	0.677	0.91
153_E	158_A	0.676	0.91
7_I	19_V	0.676	0.91
307_V	362_L	0.674	0.91
225_V	297_V	0.672	0.91
186_V	191_H	0.669	0.91
111_E	115_F	0.668	0.91
8_S	83_V	0.667	0.91
287_E	290_G	0.667	0.91
172_A	175_E	0.666	0.91
362_L	365_E	0.666	0.91
86_I	90_G	0.665	0.91
104_R	402_Q	0.664	0.91
430_R	434_L	0.664	0.91
227_I	304_I	0.664	0.91
123_G	130_A	0.663	0.91
175_E	181_P	0.663	0.91
329_D	378_L	0.663	0.91
293_R	296_Q	0.658	0.90
111_E	114_E	0.658	0.90
121_L	124_R	0.657	0.90
110_A	119_A	0.657	0.90
209_L	398_I	0.655	0.90
132_A	151_Q	0.654	0.90
236_S	240_S	0.653	0.90
313_E	342_K	0.651	0.90
198_A	202_K	0.650	0.90
48_H	52_Y	0.649	0.90
159_L	162_R	0.649	0.90
139_A	148_A	0.648	0.90
70_S	77_T	0.648	0.90
156_L	160_V	0.647	0.90
100_Q	104_R	0.646	0.89
315_S	318_D	0.646	0.89
365_E	368_I	0.644	0.89
127_L	139_A	0.644	0.89
116_T	122_N	0.643	0.89
46_E	51_H	0.643	0.89
226_I	294_S	0.642	0.89
172_A	176_V	0.641	0.89
201_V	208_L	0.641	0.89
114_E	122_N	0.641	0.89
120_F	123_G	0.640	0.89
314_L	318_D	0.640	0.89
141_T	145_M	0.640	0.89
226_I	238_L	0.640	0.89
5_A	107_A	0.639	0.89
82_D	90_G	0.637	0.89
77_T	81_E	0.636	0.89
21_L	107_A	0.634	0.89
160_V	163_L	0.634	0.89
74_A	77_T	0.634	0.89
247_A	260_I	0.634	0.89
110_A	116_T	0.633	0.88
141_T	270_P	0.633	0.88
360_T	368_I	0.632	0.88
268_G	373_E	0.632	0.88
192_Q	196_E	0.632	0.88
163_L	167_I	0.629	0.88
164_R	167_I	0.629	0.88
185_D	191_H	0.629	0.88
345_T	359_T	0.628	0.88
227_I	306_L	0.628	0.88
115_F	126_D	0.627	0.88
166_E	169_E	0.627	0.88
318_D	321_L	0.625	0.88
113_G	120_F	0.625	0.88
136_L	140_K	0.624	0.88
225_V	274_V	0.622	0.88
420_P	423_M	0.622	0.88
127_L	137_I	0.621	0.88
402_Q	405_K	0.621	0.88
171_L	425_Q	0.620	0.87
75_P	79_T	0.619	0.87
90_G	113_G	0.617	0.87
139_A	143_R	0.616	0.87
411_A	414_G	0.615	0.87
115_F	127_L	0.614	0.87
108_R	118_R	0.614	0.87
75_P	83_V	0.613	0.87
150_N	154_G	0.612	0.87
115_F	120_F	0.612	0.87
283_E	288_R	0.611	0.87
127_L	132_A	0.610	0.87
368_I	372_E	0.609	0.87
118_R	124_R	0.608	0.86
154_G	158_A	0.605	0.86
143_R	147_V	0.605	0.86
397_H	438_I	0.603	0.86
303_L	379_F	0.602	0.86
232_V	279_I	0.601	0.86
442_S	446_S	0.600	0.86
48_H	76_R	0.599	0.86
8_S	15_A	0.598	0.86
286_V	293_R	0.598	0.86
5_A	19_V	0.596	0.85
226_I	307_V	0.596	0.85
192_Q	195_V	0.595	0.85
403_Q	406_R	0.595	0.85
405_K	412_L	0.594	0.85
116_T	123_G	0.593	0.85
456_C	459_K	0.592	0.85
55_I	101_L	0.592	0.85
124_R	129_Q	0.591	0.85
433_E	442_S	0.589	0.85
54_H	66_E	0.589	0.85
52_Y	67_V	0.588	0.85
267_R	372_E	0.587	0.84
50_I	87_N	0.587	0.84
393_S	398_I	0.586	0.84
113_G	119_A	0.586	0.84
174_V	179_D	0.585	0.84
132_A	137_I	0.584	0.84
108_R	114_E	0.583	0.84
119_A	123_G	0.580	0.84
81_E	89_H	0.580	0.84
439_I	442_S	0.579	0.84
118_R	127_L	0.578	0.84
266_V	269_V	0.577	0.83
202_K	205_I	0.577	0.83
118_R	126_D	0.576	0.83
103_L	106_G	0.576	0.83
153_E	157_S	0.576	0.83
171_L	175_E	0.575	0.83
86_I	89_H	0.575	0.83
72_L	124_R	0.572	0.83
99_L	102_A	0.571	0.83
170_T	181_P	0.570	0.83
75_P	80_R	0.570	0.83
132_A	135_D	0.569	0.83
359_T	370_D	0.569	0.83
119_A	131_E	0.569	0.83
85_E	113_G	0.567	0.82
148_A	151_Q	0.565	0.82
223_S	274_V	0.565	0.82
89_H	94_T	0.565	0.82
294_S	298_L	0.565	0.82
33_I	55_I	0.564	0.82
85_E	130_A	0.564	0.82
191_H	194_L	0.563	0.82
171_L	428_L	0.563	0.82
304_I	330_V	0.560	0.82
91_G	94_T	0.557	0.81
201_V	205_I	0.556	0.81
241_L	264_V	0.556	0.81
126_D	129_Q	0.556	0.81
75_P	81_E	0.556	0.81
110_A	115_F	0.554	0.81
426_I	430_R	0.553	0.81
9_T	12_G	0.552	0.81
85_E	89_H	0.552	0.81
110_A	122_N	0.552	0.81
115_F	124_R	0.551	0.81
321_L	325_V	0.551	0.81
111_E	437_E	0.550	0.80
126_D	137_I	0.550	0.80
304_I	328_M	0.549	0.80
210_R	213_E	0.548	0.80
177_N	185_D	0.548	0.80
148_A	154_G	0.547	0.80
211_T	214_Q	0.546	0.80
243_H	365_E	0.544	0.80
356_P	378_L	0.544	0.80
89_H	127_L	0.543	0.80
167_I	428_L	0.543	0.80
225_V	294_S	0.543	0.80
34_Y	69_V	0.543	0.80
299_K	328_M	0.542	0.80
203_K	207_T	0.542	0.80
87_N	91_G	0.541	0.79
89_H	108_R	0.541	0.79
35_K	61_D	0.540	0.79
15_A	21_L	0.540	0.79
132_A	148_A	0.540	0.79
128_S	133_V	0.538	0.79
167_I	431_C	0.538	0.79
162_R	165_S	0.537	0.79
114_E	124_R	0.537	0.79
113_G	121_L	0.536	0.79
174_V	178_I	0.535	0.79
120_F	131_E	0.533	0.78
218_L	270_P	0.533	0.78
143_R	149_M	0.532	0.78
340_E	344_D	0.531	0.78
110_A	126_D	0.531	0.78
81_E	91_G	0.531	0.78
72_L	79_T	0.530	0.78
34_Y	55_I	0.528	0.78
149_M	153_E	0.528	0.78
344_D	359_T	0.527	0.78
79_T	82_D	0.526	0.77
306_L	325_V	0.526	0.77
370_D	373_E	0.526	0.77
171_L	178_I	0.526	0.77
89_H	99_L	0.524	0.77
22_S	81_E	0.524	0.77
45_V	49_T	0.523	0.77
383_A	386_S	0.523	0.77
110_A	113_G	0.523	0.77
21_L	84_I	0.522	0.77
176_V	181_P	0.522	0.77
291_V	295_R	0.522	0.77
80_R	90_G	0.521	0.77
113_G	137_I	0.520	0.77
31_D	37_P	0.519	0.77
21_L	29_I	0.518	0.76
122_N	128_S	0.517	0.76
87_N	90_G	0.517	0.76
178_I	182_E	0.516	0.76
246_K	259_V	0.516	0.76
91_G	99_L	0.515	0.76
115_F	123_G	0.515	0.76
89_H	110_A	0.515	0.76
332_V	357_V	0.515	0.76
200_A	203_K	0.515	0.76
169_E	197_K	0.514	0.76
90_G	119_A	0.514	0.76
392_V	398_I	0.514	0.76
455_F	458_G	0.513	0.76
176_V	183_Y	0.513	0.76
306_L	321_L	0.512	0.76
229_R	321_L	0.512	0.76
237_L	360_T	0.512	0.76
25_E	32_K	0.511	0.75
443_V	448_I	0.510	0.75
118_R	131_E	0.507	0.75
432_W	439_I	0.507	0.75
141_T	146_N	0.506	0.75
318_D	324_A	0.506	0.75
127_L	130_A	0.506	0.75
103_L	107_A	0.506	0.75
279_I	295_R	0.505	0.75
433_E	441_D	0.505	0.75
16_I	87_N	0.505	0.75
30_A	45_V	0.504	0.74
119_A	122_N	0.503	0.74
145_M	148_A	0.503	0.74
64_V	97_Q	0.503	0.74
440_G	451_L	0.501	0.74
48_H	71_V	0.500	0.74
358_V	371_L	0.500	0.74

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3gehA	2	0.9455	100	0.174	Contact Map
1xzpA	4	0.976	100	0.179	Contact Map
3geeA	2	0.9063	100	0.183	Contact Map
3j4jA	1	0.6558	100	0.716	Contact Map
3j65o	1	0.695	100	0.723	Contact Map
4kjzA	1	0.6318	100	0.727	Contact Map
4b43A	1	0.6253	100	0.733	Contact Map
2qtfA	1	0.6187	100	0.743	Contact Map
2e87A	1	0.7146	100	0.744	Contact Map
3wbiA	1	0.4662	100	0.746	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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